Cheap flights from New York LaGuardia Airport to St. Louis from $139

In general, August is the cheapest month to fly from New York LaGuardia Airport to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $301. The month of October is another great option to travel to St. Louis, with average flight prices from New York LaGuardia Airport averaging around $305.

The cheapest day to depart on your flight to St. Louis is on a Wednesday when prices can be found for as low as $322. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $445. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Flying to St. Louis from New York LaGuardia Airport in the morning is the least expensive time of day to depart. momondo users have found prices as low as $354 when looking at flights departing in the morning. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $372 per ticket.

Fly from New York LaGuardia to Lambert-St Louis for the best New York LaGuardia - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from New York LaGuardia Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $351 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from New York LaGuardia Airport for as low as $264 on momondo.

There are 4 cabin classes available to choose from on New York LaGuardia to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 12% on your flight if you consider stops on a New York LaGuardia Airport to St. Louis flight.

As of March 2026, prices for New York LaGuardia Airport to St. Louis flights are approximately 18% cheaper when compared to flights at the same time last year.

United Airlines, Southwest, and Delta are the most popular carriers operating from New York LaGuardia to Lambert-St Louis

Delta, American Airlines and Southwest are the top three most popular airlines that fly to St. Louis from New York LaGuardia Airport according to our data. Delta is the first choice among our users, with 42% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 4 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

As of March 2026, there are 11 flights per day flying from New York LaGuardia Airport to St. Louis. The most common time of day flights depart is 10:00AM, with 50% of flights taking off at noon.

81 flights are operational weekly from New York LaGuardia Airport to St. Louis as of March 2026. The most popular departure day for this route is Mon, with 19% of flights per week taking off on this day.