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Cheap flights from Santa Ana, California to Louisville from $161

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Louisville departing on 2/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Ana, California to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:45 am - 5:21 pm
SNA
-
SDF
6h 36m
1 stop
American Airlines Logo
6:00 am - 10:05 am
SDF
-
SNA
7h 05m
1 stop
$367American Airlines
Tue, Feb 17 - Tue, Feb 24
American Airlines Logo
12:52 pm - 12:13 am
SNA
-
SDF
8h 21m
1 stop
American Airlines Logo
6:00 am - 12:37 pm
SDF
-
SNA
9h 37m
2 stops
$372American Airlines
Tue, Feb 17 - Tue, Feb 24
American Airlines Logo
1:27 pm - 12:13 am
SNA
-
SDF
7h 46m
2 stops
American Airlines Logo
6:00 am - 12:37 pm
SDF
-
SNA
9h 37m
2 stops
$378American Airlines
Tue, Feb 17 - Tue, Feb 24
American Airlines Logo
8:17 am - 5:37 pm
SNA
-
SDF
6h 20m
1 stop
American Airlines Logo
7:40 am - 1:57 pm
SDF
-
SNA
9h 17m
1 stop
$389American Airlines
Tue, Mar 24 - Sat, Mar 28
American Airlines Logo
1:30 pm - 11:27 pm
SNA
-
SDF
6h 57m
1 stop
American Airlines Logo
6:00 am - 10:05 am
SDF
-
SNA
7h 05m
1 stop
$398American Airlines
Wed, Apr 22 - Thu, Apr 23
Delta Logo
9:45 pm - 10:16 am
SNA
-
SDF
9h 31m
1 stop
Delta Logo
3:15 pm - 10:11 pm
SDF
-
SNA
9h 56m
1 stop
$399Delta
Thu, Apr 23 - Mon, Apr 27
American Airlines Logo
12:27 pm - 11:27 pm
SNA
-
SDF
8h 00m
2 stops
American Airlines Logo
6:00 am - 10:05 am
SDF
-
SNA
7h 05m
1 stop
$403American Airlines
Wed, Apr 22 - Thu, Apr 23
American Airlines Logo
11:41 am - 11:16 pm
SNA
-
SDF
8h 35m
1 stop
American Airlines Logo
6:00 am - 12:37 pm
SDF
-
SNA
9h 37m
2 stops
$404American Airlines
Thu, Feb 12 - Sat, Feb 14
American Airlines Logo
1:27 pm - 11:58 pm
SNA
-
SDF
7h 31m
2 stops
American Airlines Logo
6:00 am - 10:05 am
SDF
-
SNA
7h 05m
1 stop
$418American Airlines
Tue, Mar 24 - Sat, Mar 28
Southwest Logo
11:00 am - 10:25 pm
SNA
-
SDF
8h 25m
2 stops
Southwest Logo
10:35 am - 2:35 pm
SDF
-
SNA
7h 00m
1 stop
$423Southwest
Mon, Mar 2 - Thu, Mar 5

Southwest flights from Santa Ana, California to Louisville

Our best Southwest deals on Santa Ana, California to Louisville flight tickets
Southwest
Mar 2
SNA11:00 amSanta Ana J. Wayne/Orange Cnty
8h 25m
2 stops
SDF10:25 pmLouisville Intl
Mar 5
SDF10:35 amLouisville Intl
7h 00m
1 stop
SNA2:35 pmSanta Ana J. Wayne/Orange Cnty
$423
Southwest
May 11
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
12h 35m
2 stops
SDF10:20 pmLouisville Intl
May 15
SDF2:40 pmLouisville Intl
8h 40m
2 stops
SNA8:20 pmSanta Ana J. Wayne/Orange Cnty
$434
Southwest
Mar 2
SNA11:00 amSanta Ana J. Wayne/Orange Cnty
8h 25m
2 stops
SDF10:25 pmLouisville Intl
Mar 5
SDF3:35 pmLouisville Intl
9h 40m
2 stops
SNA10:15 pmSanta Ana J. Wayne/Orange Cnty
$458

Spirit Airlines flights from Santa Ana, California to Louisville

Our best Spirit Airlines deals on Santa Ana, California to Louisville flight tickets
Spirit Airlines
Jan 31
SNA4:37 pmSanta Ana J. Wayne/Orange Cnty
19h 04m
3 stops
SDF2:41 pmLouisville Intl
Feb 2
SDF1:55 pmLouisville Intl
28h 47m
3 stops
SNA3:42 pmSanta Ana J. Wayne/Orange Cnty
$523
Spirit Airlines
Jan 31
SNA4:37 pmSanta Ana J. Wayne/Orange Cnty
19h 04m
2 stops
SDF2:41 pmLouisville Intl
Feb 2
SDF1:55 pmLouisville Intl
25h 30m
3 stops
SNA12:25 pmSanta Ana J. Wayne/Orange Cnty
$575

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 16, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Tue 2/17

7:45 am-5:21 pm

1 stop6h 36m

Louisville Intl

Tue 2/24

6:00 am-10:05 am

1 stop7h 05m

$367

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Tue 2/17

12:52 pm-12:13 am

1 stop8h 21m

Louisville Intl

Tue 2/24

6:00 am-12:37 pm

2 stops9h 37m

$372

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Tue 2/17

1:27 pm-12:13 am

2 stops7h 46m

Louisville Intl

Tue 2/24

6:00 am-12:37 pm

2 stops9h 37m

$378

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Tue 3/24

8:17 am-5:37 pm

1 stop6h 20m

Louisville Intl

Sat 3/28

7:40 am-1:57 pm

1 stop9h 17m

$389

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Wed 4/22

1:30 pm-11:27 pm

1 stop6h 57m

Louisville Intl

Thu 4/23

6:00 am-10:05 am

1 stop7h 05m

$398

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Thu 4/23

9:45 pm-10:16 am

1 stop9h 31m

Louisville Intl

Mon 4/27

3:15 pm-10:11 pm

1 stop9h 56m

$399

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Wed 4/22

12:27 pm-11:27 pm

2 stops8h 00m

Louisville Intl

Thu 4/23

6:00 am-10:05 am

1 stop7h 05m

$403

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Thu 2/12

11:41 am-11:16 pm

1 stop8h 35m

Louisville Intl

Sat 2/14

6:00 am-12:37 pm

2 stops9h 37m

$404

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Tue 3/24

1:27 pm-11:58 pm

2 stops7h 31m

Louisville Intl

Sat 3/28

6:00 am-10:05 am

1 stop7h 05m

$418

Santa AnaLouisville

SNA - SDF

SNASDF

Santa Ana J. Wayne/Orange Cnty

Mon 3/2

11:00 am-10:25 pm

2 stops8h 25m

Louisville Intl

Thu 3/5

10:35 am-2:35 pm

1 stop7h 00m

$423

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from Santa Ana, California to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Louisville?

If you are unable to visit Louisville during the month of May, then departing from Santa Ana, California during the month September is also very affordable. Most momondo users find prices during this month for around $403.

What is the cheapest day to depart on your flight to Louisville?

On average, the least expensive day to fly to Louisville from Santa Ana, California is on a Friday. momondo users have found tickets for Friday departures for as low as $138. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from Santa Ana, California to Louisville on a Monday will generally be more expensive and average around $240. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Louisville?

Our data shows that the cheapest Santa Ana, California to Louisville flights are usually those with departure times at noon. Our users have found flights to Louisville at noon for as low as $132. In the morning is when there is more demand to fly to Louisville, so prices are often more expensive at around $190 per ticket.

How have Santa Ana, California to Louisville flight prices changed over time?

When to book flights from Santa Ana, California to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Louisville (SNA to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Louisville

Fastest flight time

6h 05m

Direct flights

None
The fastest flight from Santa Ana, California to Louisville takes 6h 05m
There are no direct flights from Santa Ana, California to Louisville. There are no popular flight routes from Santa Ana, California to Louisville.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Louisville Intl by plane?

    Santa Ana J. Wayne/Orange Cnty and Louisville Intl are 1811.3 mi apart from one another. A reasonable flight in good conditions will take 6h 05m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Louisville Intl Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Louisville Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Louisville Intl Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Louisville Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The travel and health documents required for your trip to Louisville Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Louisville Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santa Ana, California to Louisville?

Best airlines flying from Santa Ana, California to Louisville

Compare and see reviews for airlines that fly from Santa Ana, California to Louisville with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $114Free CancellationRating
6.3
8,321 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $260Free CancellationRating
7.4
9,163 reviews
Search United Airlines flights
American AirlinesPriceFrom $324Free CancellationRating
7.2
11,138 reviews
Search American Airlines flights
DeltaPriceFrom $342Free CancellationRating
7.9
8,054 reviews
Search Delta flights
SouthwestPriceFrom $402Free CancellationRating
8.0
4,260 reviews
Search Southwest flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
West Baden Springs
Bardstown
Jeffersonville
Shepherdsville
New Albany
Corydon
Elizabeth
Charlestown
Brandenburg
Springfield
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Louisville?

Finding the right flight to Louisville from Santa Ana is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Louisville quick and easy, saving you time and money.

Can I find flights from Santa Ana to Louisville with flexible booking policies on momondo?

Flights from Santa Ana to Louisville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santa Ana to Louisville?

momondo helps you find the best flight between Santa Ana and Louisville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santa Ana to Louisville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santa Ana to Louisville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Louisville and let you know when they change.

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