What airlines fly to Iowa?

American Airlines, United Airlines and Allegiant Air are the top three most popular airlines that fly to Iowa from Santa Ana, California according to our data. American Airlines is the first choice among our users, with 56% of people opting to fly with this airline when traveling to Iowa. Keep in mind that there are 7 different airlines that fly to Iowa on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to Iowa?

Frontier, American Airlines, and Southwest are the most popular carriers operating from Santa Ana J. Wayne/Orange Cnty to Iowa

When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Iowa?

Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Iowa are updated daily.

How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Iowa?

As of October 2026, there are 3 operators available to choose from for flights from Santa Ana J. Wayne/Orange Cnty Airport to Iowa.

How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Iowa?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to Iowa.

What documentation or ID do you need to fly to Iowa?

The required travel and health documents for your Iowa trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Iowa. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$125 Cheap Flights from Santa Ana, California to Iowa in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Ana, California to Iowa

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:50 pm - 10:07 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

3h 17mnonstop

1:42 pm - 3:20 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 38mnonstop

$156Allegiant Air

Thu, Nov 12 - Sun, Nov 15

4:50 pm - 10:07 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

3h 17mnonstop

1:42 pm - 3:20 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 38mnonstop

$167Allegiant Air

Thu, Nov 12 - Sun, Nov 15

11:38 am - 7:35 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

5h 57m1 stop Denver Intl

1:42 pm - 3:20 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 38mnonstop

$209Multiple Airlines

Fri, Nov 13 - Sun, Nov 15

4:50 pm - 10:07 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

3h 17mnonstop

1:42 pm - 3:20 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 38mnonstop

$215Allegiant Air

Thu, Nov 5 - Sun, Nov 8

11:38 am - 7:35 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

5h 57m1 stop Denver Intl

8:04 pm - 3:03 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

20h 59m1 stop Las Vegas Harry Reid Intl

$234Multiple Airlines

Fri, Nov 13 - Mon, Nov 16

7:30 am - 8:04 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

10h 34m1 stop Las Vegas Harry Reid Intl

1:42 pm - 3:20 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 38mnonstop

$243Multiple Airlines

Thu, Nov 12 - Sun, Nov 15

1:23 pm - 8:18 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

4h 55m1 stop Phoenix Sky Harbor Intl

3:31 pm - 10:34 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

9h 03m1 stop Dallas/Fort Worth

$355American Airlines

Sat, Nov 14 - Mon, Nov 16

1:25 pm - 8:59 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

5h 34m1 stop Phoenix Sky Harbor Intl

2:05 pm - 9:32 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

9h 27m1 stop Chicago O'Hare Intl

$355American Airlines

Sat, Dec 5 - Sat, Dec 12

2:22 pm - 10:59 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

6h 37m1 stop Chicago O'Hare Intl

5:09 pm - 9:19 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

6h 10m1 stop Denver Intl

$355United Airlines

Sat, Nov 14 - Mon, Nov 16

2:22 pm - 10:59 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

6h 37m1 stop Chicago O'Hare Intl

5:09 pm - 9:19 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

6h 10m1 stop Denver Intl

$355United Airlines

Thu, Nov 5 - Thu, Nov 12

Cheap last minute flights

Enter your travel dates to find the best prices.

4:30 pm - 11:59 pmSNA Santa Ana J. Wayne/Orange Cnty-CID Cedar Rapids

5h 29m1 stop Phoenix Sky Harbor Intl

3:56 pm - 10:29 pmCID Cedar Rapids-SNA Santa Ana J. Wayne/Orange Cnty

8h 33m1 stop Dallas/Fort Worth

$469American Airlines

Wed, Oct 21 - Sat, Oct 24

11:32 am - 9:56 pmSNA Santa Ana J. Wayne/Orange Cnty-CID Cedar Rapids

8h 24m1 stop Atlanta Hartsfield-Jackson

11:00 am - 10:30 pmCID Cedar Rapids-SNA Santa Ana J. Wayne/Orange Cnty

13h 30m2 stops Minneapolis St Paul Seattle/Tacoma Intl

$525Delta

Wed, Oct 21 - Sat, Oct 24

1:25 pm - 11:00 pmSNA Santa Ana J. Wayne/Orange Cnty-CID Cedar Rapids

7h 35m2 stops Salt Lake City Minneapolis St Paul

5:30 am - 4:05 pmCID Cedar Rapids-SNA Santa Ana J. Wayne/Orange Cnty

12h 35m2 stops Atlanta Hartsfield-Jackson Salt Lake City

$528Delta

Fri, Oct 16 - Tue, Oct 20

3:30 pm - 12:20 amSNA Santa Ana J. Wayne/Orange Cnty-CID Cedar Rapids

6h 50m1 stop Chicago O'Hare Intl

3:56 pm - 10:29 pmCID Cedar Rapids-SNA Santa Ana J. Wayne/Orange Cnty

8h 33m1 stop Dallas/Fort Worth

$557American Airlines

Fri, Oct 16 - Fri, Oct 23

11:29 am - 8:51 pmSNA Santa Ana J. Wayne/Orange Cnty-CID Cedar Rapids

7h 22m1 stop Denver Intl

5:30 am - 9:29 amCID Cedar Rapids-SNA Santa Ana J. Wayne/Orange Cnty

5h 59m1 stop Denver Intl

$581United Airlines

Sat, Oct 17 - Wed, Oct 21

6:45 am - 5:23 pmSNA Santa Ana J. Wayne/Orange Cnty-CID Cedar Rapids

8h 38m1 stop Chicago O'Hare Intl

9:07 am - 3:13 pmCID Cedar Rapids-SNA Santa Ana J. Wayne/Orange Cnty

8h 06m1 stop Denver Intl

$581United Airlines

Sat, Oct 17 - Tue, Oct 20

11:29 am - 10:47 pmSNA Santa Ana J. Wayne/Orange Cnty-CID Cedar Rapids

9h 18m2 stops Denver Intl Chicago O'Hare Intl

5:30 am - 9:29 amCID Cedar Rapids-SNA Santa Ana J. Wayne/Orange Cnty

5h 59m1 stop Denver Intl

$582United Airlines

Fri, Oct 16 - Fri, Oct 23

11:32 am - 9:56 pmSNA Santa Ana J. Wayne/Orange Cnty-CID Cedar Rapids

8h 24m1 stop Atlanta Hartsfield-Jackson

5:30 am - 4:05 pmCID Cedar Rapids-SNA Santa Ana J. Wayne/Orange Cnty

12h 35m2 stops Atlanta Hartsfield-Jackson Salt Lake City

$665Delta

Fri, Oct 16 - Tue, Oct 20

8:00 am - 7:00 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

9h 00m1 stop Dallas/Fort Worth

5:06 am - 11:45 amDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

8h 39m1 stop Phoenix Sky Harbor Intl

$1,648American Airlines

Wed, Oct 21 - Wed, Oct 28

3:30 pm - 12:14 amSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

6h 44m1 stop Chicago O'Hare Intl

6:29 pm - 9:59 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

5h 30m1 stop Phoenix Sky Harbor Intl

$1,651American Airlines

Mon, Oct 19 - Sun, Oct 25

Cheap direct flights

Enter your travel dates to find the best prices.

4:50 pm - 10:07 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

3h 17mnonstop

1:42 pm - 3:20 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 38mnonstop

$156Allegiant Air

Thu, Nov 12 - Sun, Nov 15

4:50 pm - 10:07 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

3h 17mnonstop

1:42 pm - 3:20 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 38mnonstop

$167Allegiant Air

Thu, Nov 12 - Sun, Nov 15

4:50 pm - 10:07 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

3h 17mnonstop

1:42 pm - 3:20 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 38mnonstop

$215Allegiant Air

Thu, Nov 5 - Sun, Nov 8

4:50 pm - 10:07 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

3h 17mnonstop

2:22 pm - 4:00 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 38mnonstop

$225Allegiant Air

Thu, Nov 5 - Thu, Nov 12

4:10 pm - 9:27 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

3h 17mnonstop

2:22 pm - 4:00 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 38mnonstop

$297Allegiant Air

Sun, Nov 8 - Thu, Nov 12

10:10 am - 3:29 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

3h 19mnonstop

7:30 am - 9:20 amDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 50mnonstop

$385Allegiant Air

Wed, Dec 23 - Wed, Dec 30

10:10 am - 3:29 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

3h 19mnonstop

2:32 pm - 4:22 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 50mnonstop

$429Allegiant Air

Sat, Dec 26 - Mon, Dec 28

10:10 am - 3:29 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

3h 19mnonstop

2:32 pm - 4:22 pmDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 50mnonstop

$480Allegiant Air

Wed, Dec 23 - Mon, Dec 28

10:10 am - 3:29 pmSNA Santa Ana J. Wayne/Orange Cnty-DSM Des Moines

3h 19mnonstop

7:30 am - 9:20 amDSM Des Moines-SNA Santa Ana J. Wayne/Orange Cnty

3h 50mnonstop

$513Allegiant Air

Wed, Dec 23 - Sat, Dec 26

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Allegiant Air flights from Santa Ana, California to Iowa

Our best Allegiant Air deals on Santa Ana, California to Iowa flight tickets

Allegiant Air

Nov 12

SNA4:50 pmSanta Ana J. Wayne/Orange Cnty

3h 17m

DSM10:07 pmDes Moines

Nov 15

DSM1:42 pmDes Moines

3h 38m

SNA3:20 pmSanta Ana J. Wayne/Orange Cnty

$156

Allegiant Air

Nov 12

SNA4:50 pmSanta Ana J. Wayne/Orange Cnty

3h 17m

DSM10:07 pmDes Moines

Nov 15

DSM1:42 pmDes Moines

3h 38m

SNA3:20 pmSanta Ana J. Wayne/Orange Cnty

$167

Allegiant Air

Nov 5

SNA4:50 pmSanta Ana J. Wayne/Orange Cnty

3h 17m

DSM10:07 pmDes Moines

Nov 8

DSM1:42 pmDes Moines

3h 38m

SNA3:20 pmSanta Ana J. Wayne/Orange Cnty

$215

Delta flights from Santa Ana, California to Iowa

Our best Delta deals on Santa Ana, California to Iowa flight tickets

Delta

Nov 13

SNA12:47 pmSanta Ana J. Wayne/Orange Cnty

6h 26m

1 stop

DSM9:13 pmDes Moines

Nov 14

DSM4:00 pmDes Moines

6h 55m

1 stop

SNA8:55 pmSanta Ana J. Wayne/Orange Cnty

$355

Delta

Nov 9

SNA9:53 amSanta Ana J. Wayne/Orange Cnty

9h 20m

2 stops

DSM9:13 pmDes Moines

Nov 17

DSM2:48 pmDes Moines

8h 07m

1 stop

SNA8:55 pmSanta Ana J. Wayne/Orange Cnty

$360

Delta

Nov 9

SNA9:53 amSanta Ana J. Wayne/Orange Cnty

9h 20m

2 stops

DSM9:13 pmDes Moines

Nov 13

DSM11:00 amDes Moines

13h 30m

2 stops

SNA10:30 pmSanta Ana J. Wayne/Orange Cnty

$366

momondo Fare Finder

Use the filters below to find and compare flights from Santa Ana, California to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 11/12

4:50 pm-10:07 pm

Nonstop3h 17m

Des Moines

Sun 11/15

1:42 pm-3:20 pm

Nonstop3h 38m

$156

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 11/12

4:50 pm-10:07 pm

Nonstop3h 17m

Des Moines

Sun 11/15

1:42 pm-3:20 pm

Nonstop3h 38m

$167

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Fri 11/13

11:38 am-7:35 pm

1 stop5h 57m

Des Moines

Sun 11/15

1:42 pm-3:20 pm

Nonstop3h 38m

$209

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 11/5

4:50 pm-10:07 pm

Nonstop3h 17m

Des Moines

Sun 11/8

1:42 pm-3:20 pm

Nonstop3h 38m

$215

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Fri 11/13

11:38 am-7:35 pm

1 stop5h 57m

Des Moines

Mon 11/16

8:04 pm-3:03 pm

1 stop20h 59m

$234

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 11/12

7:30 am-8:04 pm

1 stop10h 34m

Des Moines

Sun 11/15

1:42 pm-3:20 pm

Nonstop3h 38m

$243

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Sat 11/14

1:23 pm-8:18 pm

1 stop4h 55m

Des Moines

Mon 11/16

3:31 pm-10:34 pm

1 stop9h 03m

$355

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Sat 12/5

1:25 pm-8:59 pm

1 stop5h 34m

Des Moines

Sat 12/12

2:05 pm-9:32 pm

1 stop9h 27m

$355

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Sat 11/14

2:22 pm-10:59 pm

1 stop6h 37m

Des Moines

Mon 11/16

5:09 pm-9:19 pm

1 stop6h 10m

$355

Santa AnaDes Moines

SNA Santa Ana J. Wayne/Orange Cnty - DSM Des Moines

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 11/5

2:22 pm-10:59 pm

1 stop6h 37m

Des Moines

Thu 11/12

5:09 pm-9:19 pm

1 stop6h 10m

$355

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santa Ana, California to Iowa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Iowa?

The month of October is another great option to travel to Iowa, with average flight prices from Santa Ana, California averaging around $287.

What is the cheapest day to depart on your flight to Iowa?

The cheapest day to depart from Santa Ana, California to Iowa is on a Monday when prices can be found for as low as $162. If your travel schedule is flexible, try to avoid departing on a Wednesday because tickets tend to average around $462. These prices are subject to change though, so be sure to set up a Price Alert for flights to Iowa.

What is the cheapest time of day to depart on your flight to Iowa?

Our most recent data shows that the best time of day to fly to Iowa is in the morning. Flights from Santa Ana, California to Iowa during this time can be as low as $199. Try not to purchase tickets in the afternoon because they tend to be around $220. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Santa Ana J. Wayne/Orange Cnty to Iowa flight route?

Fly from Santa Ana J. Wayne/Orange Cnty to Des Moines for the best Santa Ana J. Wayne/Orange Cnty - Iowa flight prices

What cabin class options are available on Santa Ana, California to Iowa flights?

There is only 1 cabin class available to choose from on Santa Ana, California to Iowa flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santa Ana, California to Iowa flights?

No. A direct flight is the cheapest option for a flight between Santa Ana, California to Iowa.

Cheap Santa Ana, California to Iowa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Iowa

Best Price Found	$125
Fastest flight time	3h 15m
Direct flights	Mon, Thu, Fri, Sat and Sun
Airports in Iowa	41 airports

The best one-way flight to Iowa from Santa Ana, California in the past 72 hours is $125. The best round-trip flight deal from Santa Ana, California to Iowa found on momondo in the last 72 hours is $156.

The fastest flight from Santa Ana, California to Iowa takes 3h 15m

Direct flights go from Santa Ana, California to Iowa on Monday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.

There are 41 airports in Iowa. From Santa Ana, California there are direct flights to Des Moines (DSM).

Search flight deals

Frequently asked questions about flying from Santa Ana, California to Iowa

When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Iowa?
Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Iowa are updated daily.
How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Iowa?
As of October 2026, there are 3 operators available to choose from for flights from Santa Ana J. Wayne/Orange Cnty Airport to Iowa.
How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Iowa?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Ana J. Wayne/Orange Cnty Airport to Iowa.
What documentation or ID do you need to fly to Iowa?
The required travel and health documents for your Iowa trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Iowa. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Santa Ana, California to Iowa?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Santa Ana, California to Iowa is Airbus A320-100/200 (64.58% of total bookings). The next most popular plane models are Embraer 175 (12.50%), Airbus A319 (8.33%), and Embraer 175 (Enhanced Winglets) (8.33%).

Best airlines flying from Santa Ana, California to Iowa

Compare and see reviews for airlines that fly from Santa Ana, California to Iowa with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $141	Free Cancellation	Rating 7.3 677 reviews	Search Allegiant Air flights
American Airlines	PriceFrom $260	Free Cancellation	Rating 7.0 12,169 reviews	Search American Airlines flights
United Airlines	PriceFrom $330	Free Cancellation	Rating 7.4 10,369 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Iowa?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Iowa from Santa Ana.

Can I find flights from Santa Ana to Iowa with flexible booking policies on momondo?

momondo does allow users to show only those flights to Iowa from Santa Ana which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santa Ana to Iowa?

Once all potential Santa Ana to Iowa flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Ana to Iowa right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santa Ana to Iowa now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Iowa and let you know when they change.