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Cheap flights from Chicago O'Hare Intl Airport to Des Moines from $105

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Chicago O'Hare Intl Airport to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
8:55 am - 10:37 amORD  Chicago O'Hare Intl-DSM Des Moines
1h 42mnonstop
United Airlines Logo
11:22 am - 1:00 pmDSM  Des Moines-ORD Chicago O'Hare Intl
1h 38mnonstop
$218United Airlines
Wed, Dec 16 - Wed, Jan 13
American Airlines Logo
11:50 am - 1:35 pmORD  Chicago O'Hare Intl-DSM Des Moines
1h 45mnonstop
American Airlines Logo
7:31 pm - 9:24 pmDSM  Des Moines-ORD Chicago O'Hare Intl
1h 53mnonstop
$237American Airlines
Sat, Dec 12 - Sat, Dec 12
United Airlines Logo
7:55 pm - 9:25 pmORD  Chicago O'Hare Intl-DSM Des Moines
1h 30mnonstop
United Airlines Logo
6:18 pm - 7:59 pmDSM  Des Moines-ORD Chicago O'Hare Intl
1h 41mnonstop
$237United Airlines
Fri, Dec 11 - Mon, Dec 14
United Airlines Logo
7:45 pm - 9:23 pmORD  Chicago O'Hare Intl-DSM Des Moines
1h 38mnonstop
United Airlines Logo
3:10 pm - 4:48 pmDSM  Des Moines-ORD Chicago O'Hare Intl
1h 38mnonstop
$237United Airlines
Mon, Jan 11 - Tue, Jan 26
American Airlines Logo
10:45 pm - 12:19 amORD  Chicago O'Hare Intl-DSM Des Moines
1h 34mnonstop
American Airlines Logo
7:24 pm - 9:14 pmDSM  Des Moines-ORD Chicago O'Hare Intl
1h 50mnonstop
$237American Airlines
Wed, Nov 25 - Fri, Nov 27
American Airlines Logo
7:20 am - 8:55 amORD  Chicago O'Hare Intl-DSM Des Moines
1h 35mnonstop
American Airlines Logo
7:24 pm - 9:14 pmDSM  Des Moines-ORD Chicago O'Hare Intl
1h 50mnonstop
$237American Airlines
Sat, Nov 21 - Mon, Nov 23
United Airlines Logo
9:20 pm - 10:51 pmORD  Chicago O'Hare Intl-DSM Des Moines
1h 31mnonstop
United Airlines Logo
6:30 pm - 8:11 pmDSM  Des Moines-ORD Chicago O'Hare Intl
1h 41mnonstop
$237United Airlines
Thu, Feb 11 - Mon, Feb 15
Delta Logo
5:33 pm - 9:31 pmORD  Chicago O'Hare Intl-DSM Des Moines
3h 58m1 stop Minneapolis St Paul
Delta Logo
4:53 pm - 9:35 pmDSM  Des Moines-ORD Chicago O'Hare Intl
4h 42m1 stop Minneapolis St Paul
$257Delta
Thu, Dec 3 - Mon, Dec 7
Delta Logo
6:20 am - 10:21 amORD  Chicago O'Hare Intl-DSM Des Moines
4h 01m1 stop Minneapolis St Paul
Delta Logo
4:53 pm - 9:35 pmDSM  Des Moines-ORD Chicago O'Hare Intl
4h 42m1 stop Minneapolis St Paul
$257Delta
Thu, Dec 3 - Mon, Dec 7
Delta Logo
12:34 pm - 4:11 pmORD  Chicago O'Hare Intl-DSM Des Moines
3h 37m1 stop Minneapolis St Paul
Delta Logo
4:53 pm - 9:35 pmDSM  Des Moines-ORD Chicago O'Hare Intl
4h 42m1 stop Minneapolis St Paul
$257Delta
Fri, Dec 11 - Mon, Dec 14

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Delta flights from Chicago O'Hare Intl Airport to Des Moines

Our best Delta deals on Chicago O'Hare Intl Airport to Des Moines flight tickets
Delta
Dec 3
ORD6:20 amChicago O'Hare Intl
4h 01m
1 stop
DSM10:21 amDes Moines
Dec 7
DSM4:53 pmDes Moines
4h 42m
1 stop
ORD9:35 pmChicago O'Hare Intl
$257
Delta
Dec 14
ORD12:34 pmChicago O'Hare Intl
3h 37m
1 stop
DSM4:11 pmDes Moines
Dec 17
DSM6:41 amDes Moines
5h 03m
1 stop
ORD11:44 amChicago O'Hare Intl
$294
Delta
Dec 4
ORD3:47 pmChicago O'Hare Intl
5h 44m
1 stop
DSM9:31 pmDes Moines
Dec 6
DSM6:41 amDes Moines
5h 03m
1 stop
ORD11:44 amChicago O'Hare Intl
$308

Frontier flights from Chicago O'Hare Intl Airport to Des Moines

Our best Frontier deals on Chicago O'Hare Intl Airport to Des Moines flight tickets
Frontier
Dec 3
ORD7:00 amChicago O'Hare Intl
12h 40m
1 stop
DSM7:40 pmDes Moines
Dec 7
DSM7:31 pmDes Moines
1h 53m
ORD9:24 pmChicago O'Hare Intl
$339
Frontier
Nov 16
ORD6:30 amChicago O'Hare Intl
13h 05m
1 stop
DSM7:35 pmDes Moines
Nov 22
DSM8:28 pmDes Moines
28h 25m
1 stop
ORD12:53 amChicago O'Hare Intl
$340
Frontier
Nov 6
ORD6:30 amChicago O'Hare Intl
13h 05m
1 stop
DSM7:35 pmDes Moines
Nov 9
DSM8:30 pmDes Moines
27h 51m
1 stop
ORD12:21 amChicago O'Hare Intl
$383

momondo Fare Finder

 
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Wed 12/16

8:55 am-10:37 am

Nonstop1h 42m

Des Moines

Wed 1/13

11:22 am-1:00 pm

Nonstop1h 38m

$218

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Sat 12/12

11:50 am-1:35 pm

Nonstop1h 45m

Des Moines

Sat 12/12

7:31 pm-9:24 pm

Nonstop1h 53m

$237
Quickest round-trip

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Fri 12/11

7:55 pm-9:25 pm

Nonstop1h 30m

Des Moines

Mon 12/14

6:18 pm-7:59 pm

Nonstop1h 41m

$237

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Mon 1/11

7:45 pm-9:23 pm

Nonstop1h 38m

Des Moines

Tue 1/26

3:10 pm-4:48 pm

Nonstop1h 38m

$237

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Wed 11/25

10:45 pm-12:19 am

Nonstop1h 34m

Des Moines

Fri 11/27

7:24 pm-9:14 pm

Nonstop1h 50m

$237

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Sat 11/21

7:20 am-8:55 am

Nonstop1h 35m

Des Moines

Mon 11/23

7:24 pm-9:14 pm

Nonstop1h 50m

$237

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Thu 2/11

9:20 pm-10:51 pm

Nonstop1h 31m

Des Moines

Mon 2/15

6:30 pm-8:11 pm

Nonstop1h 41m

$237

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Thu 12/3

5:33 pm-9:31 pm

1 stop3h 58m

Des Moines

Mon 12/7

4:53 pm-9:35 pm

1 stop4h 42m

$257

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Thu 12/3

6:20 am-10:21 am

1 stop4h 01m

Des Moines

Mon 12/7

4:53 pm-9:35 pm

1 stop4h 42m

$257

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Fri 12/11

12:34 pm-4:11 pm

1 stop3h 37m

Des Moines

Mon 12/14

4:53 pm-9:35 pm

1 stop4h 42m

$257

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago O'Hare Intl Airport and Des Moines?

Prices are currently low for flights on this route.

Typical prices usually range from $334 to $470.
The lowest price recently found on this route was $195.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in December, then February is your next best option. Flight prices from Chicago O'Hare Intl Airport to Des Moines during February average around $364.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Chicago O'Hare Intl Airport to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $313. Flights from Chicago O'Hare Intl Airport to Des Moines on a Tuesday will generally be more expensive and average around $470. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Chicago O'Hare Intl Airport to Des Moines at noon for as low as $249. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $478. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago O'Hare Intl to Des Moines flight route?

Fly from Chicago O'Hare Intl to Des Moines for the best Chicago O'Hare Intl - Des Moines flight prices

What cabin class options are available on Chicago O'Hare Intl Airport to Des Moines flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl Airport to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Des Moines flights?

You could potentially save up to 22% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Des Moines flight.

How have Chicago O'Hare Intl Airport to Des Moines flight prices changed over time?

As of November 2026, prices for Chicago O'Hare Intl Airport to Des Moines flights are approximately 18% cheaper when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Des Moines (ORD to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Des Moines

Best Price Found

$105

Fastest flight time

1h 28m

Direct flights

Every day

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Chicago O'Hare Intl Airport in the past 72 hours is $105. The best round-trip flight deal from Chicago O'Hare Intl Airport to Des Moines found on momondo in the last 72 hours is $218.
The fastest flight from Chicago O'Hare Intl Airport to Des Moines takes 1h 28m
Direct flights go from Chicago O'Hare Intl Airport to Des Moines every day.
There is 1 airport in Des Moines. From Chicago O'Hare Intl Airport there are direct flights to Des Moines (DSM).
Search flight deals

Frequently asked questions about flying from Chicago O'Hare Intl Airport to Des Moines

  • How far is Chicago O'Hare Intl to Des Moines by plane?

    A flight from Chicago O'Hare Intl to Des Moines will travel around 295.9 mi. A reasonable flight in good conditions will take 1h 28m.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Des Moines Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Des Moines Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Des Moines?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Des Moines?

Best airlines flying from Chicago O'Hare Intl Airport to Des Moines

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $211Free CancellationRating
7.0
12,230 reviews
Search American Airlines flights
United AirlinesPriceFrom $217Free CancellationRating
7.3
10,459 reviews
Search United Airlines flights

  • United Airlines Flights From Chicago O'Hare Intl Airport to Des Moines

    Across 26 United Airlines flights from Chicago O'Hare Intl Airport to Des Moines this week, the average price was $455, with the best United Airlines deals starting from $217 round-trip. 10,459 users have rated United Airlines on momondo, with an average score of 7.3/10.

  • American Airlines Flights From Chicago O'Hare Intl Airport to Des Moines

    Another popular option for Chicago O'Hare Intl Airport to Des Moines flights is American Airlines (7.0/10, 12,230 ratings). American Airlines flies from Chicago O'Hare Intl Airport to Des Moines around 26 times per week, with deals starting from $211 round-trip and rising to an average price of around $387.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Urbandale
Osceola
Boone
Johnston
Newton
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Chicago.

Can I find flights from Chicago to Des Moines with flexible booking policies on momondo?

Flights from Chicago to Des Moines with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Chicago.

I’m not ready to book a flight from Chicago to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Chicago to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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