What is the cheapest airline that flies from Chicago O'Hare Intl to Des Moines?

Frontier, Delta, and Southwest are the most popular carriers operating from Chicago O'Hare Intl to Des Moines

When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Des Moines Airport?

Prices for flights from Chicago O'Hare Intl Airport to Des Moines Airport were last updated today.

How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Des Moines Airport?

There are 2 operators available for flights from Chicago O'Hare Intl Airport to Des Moines Airport as of November 2025.

How old do you have to be to fly from Chicago O'Hare Intl Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$61 Cheap Flights from Chicago O'Hare Intl Airport to Des Moines in 2025/26

Q: How many flights depart from Chicago O'Hare Intl Airport to Des Moines on average per week?

As of November 2025, 245 flights take off from Chicago O'Hare Intl Airport and land in Des Moines each week. The most common flight departure day for this route is Thu, with 17% of weekly flights taking off on this day.

Q: How many flights depart from Chicago O'Hare Intl Airport to Des Moines on average per day?

The number of flights available between Chicago O'Hare Intl Airport and Des Moines is 35 per day as of November 2025. The most frequent departure time is 4:00PM, with 41% of daily flights leaving in the afternoon.

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Find the cheapest flights from Chicago O'Hare Intl Airport to Des Moines

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:50 am - 3:41 pmORD-DSM

6h 51m1 stop

6:19 am - 1:21 pmDSM-ORD

7h 02m1 stop

$179Delta

Find Deal

Wed, Feb 4 - Wed, Feb 18

10:09 am - 11:42 amORD-DSM

1h 33mnonstop

5:40 am - 7:23 amDSM-ORD

1h 43mnonstop

$189American Airlines

Find Deal

Fri, Dec 5 - Fri, Dec 12

7:00 am - 7:03 pmORD-DSM

12h 03m1 stop

7:58 pm - 10:24 pmDSM-ORD

26h 26m2 stops

$190Frontier

Find Deal

Fri, Dec 5 - Fri, Dec 12

9:21 am - 7:03 pmORD-DSM

33h 42m2 stops

4:21 pm - 2:16 pmDSM-ORD

21h 55m1 stop

$213Multiple Airlines

Find Deal

Thu, Dec 4 - Thu, Dec 11

8:05 pm - 9:32 pmORD-DSM

1h 27mnonstop

1:05 pm - 2:40 pmDSM-ORD

1h 35mnonstop

$219United Airlines

Find Deal

Thu, Nov 20 - Sat, Nov 22

7:00 am - 7:24 pmORD-DSM

12h 24m1 stop

2:56 pm - 12:09 amDSM-ORD

9h 13m1 stop

$222Multiple Airlines

Find Deal

Sun, Nov 23 - Thu, Dec 11

7:00 am - 7:24 pmORD-DSM

12h 24m1 stop

2:00 pm - 10:36 pmDSM-ORD

32h 36m2 stops

$241Frontier

Find Deal

Sun, Nov 23 - Wed, Nov 26

9:06 am - 10:30 amORD-DSM

1h 24mnonstop

6:50 pm - 8:25 pmDSM-ORD

1h 35mnonstop

$249United Airlines

Find Deal

Mon, Dec 1 - Fri, Dec 12

5:15 pm - 12:05 amORD-DSM

6h 50m2 stops

6:15 am - 12:15 pmDSM-ORD

6h 00m2 stops

$315Southwest

Find Deal

Mon, Dec 1 - Fri, Dec 5

1:45 pm - 11:35 pmORD-DSM

9h 50m2 stops

6:15 am - 12:15 pmDSM-ORD

6h 00m2 stops

$328Southwest

Find Deal

Sun, Nov 23 - Thu, Dec 11

Delta flights from Chicago O'Hare Intl Airport to Des Moines

Our best Delta deals on Chicago O'Hare Intl Airport to Des Moines flight tickets

Delta

Feb 4

ORD8:50 amChicago O'Hare Intl

6h 51m

1 stop

DSM3:41 pmDes Moines

Feb 18

DSM6:19 amDes Moines

7h 02m

1 stop

ORD1:21 pmChicago O'Hare Intl

$179

Find similar

Delta

Dec 1

ORD2:35 pmChicago O'Hare Intl

6h 12m

1 stop

DSM8:47 pmDes Moines

Dec 5

DSM2:59 pmDes Moines

6h 41m

1 stop

ORD9:40 pmChicago O'Hare Intl

$195

Find similar

Delta

Dec 5

ORD11:00 amChicago O'Hare Intl

6h 03m

1 stop

DSM5:03 pmDes Moines

Dec 12

DSM4:59 pmDes Moines

4h 41m

1 stop

ORD9:40 pmChicago O'Hare Intl

$209

Find similar

American Airlines flights from Chicago O'Hare Intl Airport to Des Moines

Our best American Airlines deals on Chicago O'Hare Intl Airport to Des Moines flight tickets

American Airlines

Dec 5

ORD10:09 amChicago O'Hare Intl

1h 33m

DSM11:42 amDes Moines

Dec 12

DSM5:40 amDes Moines

1h 43m

ORD7:23 amChicago O'Hare Intl

$189

Find similar

American Airlines

Nov 20

ORD11:02 amChicago O'Hare Intl

1h 34m

DSM12:36 pmDes Moines

Nov 27

DSM5:41 amDes Moines

1h 42m

ORD7:23 amChicago O'Hare Intl

$204

Find similar

American Airlines

Nov 23

ORD11:50 amChicago O'Hare Intl

1h 26m

DSM1:16 pmDes Moines

Dec 11

DSM12:15 pmDes Moines

1h 51m

ORD2:06 pmChicago O'Hare Intl

$205

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Wed 2/4

8:50 am-3:41 pm

1 stop6h 51m

Des Moines

Wed 2/18

6:19 am-1:21 pm

1 stop7h 02m

$179

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Fri 12/5

10:09 am-11:42 am

Nonstop1h 33m

Des Moines

Fri 12/12

5:40 am-7:23 am

Nonstop1h 43m

$189

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Fri 12/5

7:00 am-7:03 pm

1 stop12h 03m

Des Moines

Fri 12/12

7:58 pm-10:24 pm

2 stops26h 26m

$190

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 12/4

9:21 am-7:03 pm

2 stops33h 42m

Des Moines

Thu 12/11

4:21 pm-2:16 pm

1 stop21h 55m

$213

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 11/20

8:05 pm-9:32 pm

Nonstop1h 27m

Des Moines

Sat 11/22

1:05 pm-2:40 pm

Nonstop1h 35m

$219

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Sun 11/23

7:00 am-7:24 pm

1 stop12h 24m

Des Moines

Thu 12/11

2:56 pm-12:09 am

1 stop9h 13m

$222

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Sun 11/23

7:00 am-7:24 pm

1 stop12h 24m

Des Moines

Wed 11/26

2:00 pm-10:36 pm

2 stops32h 36m

$241

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Mon 12/1

9:06 am-10:30 am

Nonstop1h 24m

Des Moines

Fri 12/12

6:50 pm-8:25 pm

Nonstop1h 35m

$249

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Mon 12/1

5:15 pm-12:05 am

2 stops6h 50m

Des Moines

Fri 12/5

6:15 am-12:15 pm

2 stops6h 00m

$315

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Sun 11/23

1:45 pm-11:35 pm

2 stops9h 50m

Des Moines

Thu 12/11

6:15 am-12:15 pm

2 stops6h 00m

$328

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then January is your next best option. Flight prices from Chicago O'Hare Intl Airport to Des Moines during January average around $249.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Chicago O'Hare Intl Airport to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $249. Flights from Chicago O'Hare Intl Airport to Des Moines on a Tuesday will generally be more expensive and average around $466. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Chicago O'Hare Intl Airport to Des Moines at noon for as low as $249. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $304. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago O'Hare Intl to Des Moines flight route?

Fly from Chicago O'Hare Intl to Des Moines for the best Chicago O'Hare Intl - Des Moines flight prices

What cabin class options are available on Chicago O'Hare Intl to Des Moines flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Des Moines flights?

You could potentially save up to 43% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Des Moines flight.

How have Chicago O'Hare Intl Airport to Des Moines flight prices changed over time?

As of November 2025, prices for Chicago O'Hare Intl Airport to Des Moines flights are approximately 89% more expensive when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Des Moines (ORD to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Des Moines

Best Price Found	$253
Fastest flight time	1h 20m
Direct flights	Mon, Tue, Wed, Thu, Fri and Sat
Airports in Des Moines	1 airport

The best one-way flight to Des Moines from Chicago O'Hare Intl Airport in the past 72 hours is $253. The best round-trip flight deal from Chicago O'Hare Intl Airport to Des Moines found on momondo in the last 72 hours is $193.

The fastest flight from Chicago O'Hare Intl Airport to Des Moines takes 1h 20m

Direct flights go from Chicago O'Hare Intl Airport to Des Moines on Monday, Tuesday, Wednesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.

There is 1 airport near Des Moines: Des Moines (DSM)

Search flight deals

How far is Chicago O'Hare Intl to Des Moines by plane?
A flight from Chicago O'Hare Intl to Des Moines will travel around 295.9 mi. A reasonable flight in good conditions will take 1h 20m.
When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Des Moines Airport?
Prices for flights from Chicago O'Hare Intl Airport to Des Moines Airport were last updated today.
How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Des Moines Airport?
There are 2 operators available for flights from Chicago O'Hare Intl Airport to Des Moines Airport as of November 2025.
How old do you have to be to fly from Chicago O'Hare Intl Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Chicago O'Hare Intl Airport to Des Moines?
Based on momondo bookings for flights between Chicago O'Hare Intl Airport and Des Moines, the leading plane model is Airbus A319, making up 23.03% of the total bookings. Other popular models include Boeing 737-800 with 18.94%, Canadair (Bombardier) Regional Jet 700 with 15.30%, and Embraer 175 (Enhanced Winglets) with 13.48%.
What is the most popular airline from Chicago O'Hare Intl Airport to Des Moines?
momondo data reveals that the most frequently booked airline on the route from Chicago O'Hare Intl Airport to Des Moines is United Airlines, representing 50% of all bookings. The subsequent popular airline is American Airlines at 50%.

Best airlines flying from Chicago O'Hare Intl Airport to Des Moines

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $189	Free Cancellation	Rating 7.2 11,040 reviews		Search American Airlines flights
United Airlines	PriceFrom $189	Free Cancellation	Rating 7.4 9,007 reviews		Search United Airlines flights

United Airlines Flights From Chicago O'Hare Intl Airport to Des Moines
Across 29 United Airlines flights from Chicago O'Hare Intl Airport to Des Moines this week, the average price was $270, with the best United Airlines deals starting from $189 round-trip. 9,007 users have rated United Airlines on momondo, with an average score of 7.4/10.
American Airlines Flights From Chicago O'Hare Intl Airport to Des Moines
Another popular option for Chicago O'Hare Intl Airport to Des Moines flights is American Airlines (7.2/10, 11,040 ratings). American Airlines flies from Chicago O'Hare Intl Airport to Des Moines around 27 times per week, with deals starting from $189 round-trip and rising to an average price of around $279.

West Des Moines

Ames

Ankeny

Altoona

Urbandale

Clive

Newton

Pella

Johnston

Osceola

Boone

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Chicago.

Can I find flights from Chicago to Des Moines with flexible booking policies on momondo?

Flights from Chicago to Des Moines with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Chicago.

I’m not ready to book a flight from Chicago to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Chicago to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

An easier way to manage your Des Moines trip

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Cheap flights from Chicago O'Hare Intl Airport to Des Moines from $61

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Filter for what you want

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Find the cheapest flights from Chicago O'Hare Intl Airport to Des Moines

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

Delta flights from Chicago O'Hare Intl Airport to Des Moines

Our best Delta deals on Chicago O'Hare Intl Airport to Des Moines flight tickets

American Airlines flights from Chicago O'Hare Intl Airport to Des Moines

Our best American Airlines deals on Chicago O'Hare Intl Airport to Des Moines flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Des Moines that are best for you.

See travel insights to Des Moines from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then January is your next best option. Flight prices from Chicago O'Hare Intl Airport to Des Moines during January average around $249.

What is the cheapest day to depart on your flight to Des Moines?

What is the cheapest time of day to depart on your flight to Des Moines?

What is the cheapest Chicago O'Hare Intl to Des Moines flight route?

Fly from Chicago O'Hare Intl to Des Moines for the best Chicago O'Hare Intl - Des Moines flight prices

What cabin class options are available on Chicago O'Hare Intl to Des Moines flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Des Moines flights?

You could potentially save up to 43% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Des Moines flight.

How have Chicago O'Hare Intl Airport to Des Moines flight prices changed over time?

As of November 2025, prices for Chicago O'Hare Intl Airport to Des Moines flights are approximately 89% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Chicago O'Hare Intl to Des Moines?

Frontier, Delta, and Southwest are the most popular carriers operating from Chicago O'Hare Intl to Des Moines

How many flights depart from Chicago O'Hare Intl Airport to Des Moines on average per day?

The number of flights available between Chicago O'Hare Intl Airport and Des Moines is 35 per day as of November 2025. The most frequent departure time is 4:00PM, with 41% of daily flights leaving in the afternoon.

How many flights depart from Chicago O'Hare Intl Airport to Des Moines on average per week?

As of November 2025, 245 flights take off from Chicago O'Hare Intl Airport and land in Des Moines each week. The most common flight departure day for this route is Thu, with 17% of weekly flights taking off on this day.

When to book flights from Chicago O'Hare Intl Airport to Des Moines

Cheap Chicago O'Hare Intl Airport to Des Moines (ORD to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Des Moines

Best Price Found

Fastest flight time

Direct flights

Airports in Des Moines

How far is Chicago O'Hare Intl to Des Moines by plane?

When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Des Moines Airport?

How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Des Moines Airport?

How old do you have to be to fly from Chicago O'Hare Intl Airport to Des Moines Airport?

What documentation or ID do you need to fly to Des Moines Airport?

What is the most popular plane model from Chicago O'Hare Intl Airport to Des Moines?

What is the most popular airline from Chicago O'Hare Intl Airport to Des Moines?

Best airlines flying from Chicago O'Hare Intl Airport to Des Moines

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Des Moines with momondo

United Airlines Flights From Chicago O'Hare Intl Airport to Des Moines

American Airlines Flights From Chicago O'Hare Intl Airport to Des Moines

Traveling to a place near Des Moines?

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Des Moines?

Can I find flights from Chicago to Des Moines with flexible booking policies on momondo?

How can momondo help me find flights from Chicago to Des Moines?

I’m not ready to book a flight from Chicago to Des Moines right now. Can momondo alert me if prices change?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

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