What is the cheapest airline that flies from Chicago O'Hare Intl to Des Moines?

Frontier, Delta, and Southwest are the most popular carriers operating from Chicago O'Hare Intl to Des Moines

When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Des Moines Airport?

Prices for flights from Chicago O'Hare Intl Airport to Des Moines Airport were last updated today.

How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Des Moines Airport?

There are 2 operators available for flights from Chicago O'Hare Intl Airport to Des Moines Airport as of October 2025.

How old do you have to be to fly from Chicago O'Hare Intl Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$54 Cheap Flights from Chicago O'Hare Intl Airport to Des Moines in 2025/26

Q: How many flights depart from Chicago O'Hare Intl Airport to Des Moines on average per day?

The number of flights available between Chicago O'Hare Intl Airport and Des Moines is 42 per day as of October 2025. The most frequent departure time is 4:00PM, with 43% of daily flights leaving in the afternoon.

Q: How many flights depart from Chicago O'Hare Intl Airport to Des Moines on average per week?

As of October 2025, 298 flights take off from Chicago O'Hare Intl Airport and land in Des Moines each week. The most common flight departure day for this route is Mon, with 15% of weekly flights taking off on this day.

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Find the cheapest flights from Chicago O'Hare Intl Airport to Des Moines

Round-trip

One-way

Last minute

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Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 1:56 pmORD-DSM

7h 56m1 stop

9:03 pm - 10:42 amDSM-ORD

13h 39m1 stop

$170Multiple Airlines

Find Deal

Thu, Nov 6 - Sun, Nov 9

6:00 am - 1:56 pmORD-DSM

7h 56m1 stop

9:03 pm - 10:42 amDSM-ORD

13h 39m1 stop

$174Multiple Airlines

Find Deal

Thu, Nov 6 - Sun, Nov 9

11:46 am - 1:16 pmORD-DSM

1h 30mnonstop

4:02 pm - 5:34 pmDSM-ORD

1h 32mnonstop

$189American Airlines

Find Deal

Thu, Nov 6 - Sun, Nov 9

11:46 am - 1:16 pmORD-DSM

1h 30mnonstop

6:40 pm - 8:31 pmDSM-ORD

1h 51mnonstop

$190American Airlines

Find Deal

Thu, Nov 6 - Sun, Nov 9

6:00 am - 1:47 pmORD-DSM

7h 47m1 stop

2:32 pm - 12:15 amDSM-ORD

9h 43m1 stop

$191Frontier

Find Deal

Mon, Nov 10 - Mon, Nov 17

12:59 pm - 2:19 pmORD-DSM

1h 20mnonstop

3:15 pm - 4:46 pmDSM-ORD

1h 31mnonstop

$194United Airlines

Find Deal

Sat, Nov 1 - Mon, Nov 3

6:00 am - 10:22 amORD-DSM

4h 22m1 stop

10:55 am - 2:56 pmDSM-ORD

4h 01m1 stop

$209Delta

Find Deal

Tue, Mar 3 - Wed, Mar 4

1:25 pm - 8:35 pmORD-DSM

7h 10m1 stop

3:30 pm - 9:19 pmDSM-ORD

5h 49m1 stop

$219Delta

Find Deal

Tue, Oct 28 - Sat, Nov 1

6:50 am - 1:52 pmORD-DSM

7h 02m1 stop

2:32 pm - 12:43 amDSM-ORD

10h 11m1 stop

$228Frontier

Find Deal

Sun, Oct 26 - Thu, Oct 30

9:06 am - 10:30 amORD-DSM

1h 24mnonstop

3:15 pm - 4:46 pmDSM-ORD

1h 31mnonstop

$251United Airlines

Find Deal

Thu, Nov 6 - Sun, Nov 9

American Airlines flights from Chicago O'Hare Intl Airport to Des Moines

Our best American Airlines deals on Chicago O'Hare Intl Airport to Des Moines flight tickets

American Airlines

Nov 6

ORD11:46 amChicago O'Hare Intl

1h 30m

DSM1:16 pmDes Moines

Nov 9

DSM4:02 pmDes Moines

1h 32m

ORD5:34 pmChicago O'Hare Intl

$189

Find similar

American Airlines

Nov 6

ORD11:46 amChicago O'Hare Intl

1h 30m

DSM1:16 pmDes Moines

Nov 9

DSM6:40 pmDes Moines

1h 51m

ORD8:31 pmChicago O'Hare Intl

$190

Find similar

American Airlines

Oct 28

ORD8:55 pmChicago O'Hare Intl

1h 28m

DSM10:23 pmDes Moines

Nov 1

DSM11:58 amDes Moines

1h 33m

ORD1:31 pmChicago O'Hare Intl

$199

Find similar

Frontier flights from Chicago O'Hare Intl Airport to Des Moines

Our best Frontier deals on Chicago O'Hare Intl Airport to Des Moines flight tickets

Frontier

Nov 10

ORD6:00 amChicago O'Hare Intl

7h 47m

1 stop

DSM1:47 pmDes Moines

Nov 17

DSM2:32 pmDes Moines

9h 43m

1 stop

ORD12:15 amChicago O'Hare Intl

$191

Find similar

Frontier

Oct 26

ORD6:50 amChicago O'Hare Intl

7h 02m

1 stop

DSM1:52 pmDes Moines

Oct 30

DSM2:32 pmDes Moines

10h 11m

1 stop

ORD12:43 amChicago O'Hare Intl

$228

Find similar

Frontier

Nov 10

ORD6:00 amChicago O'Hare Intl

7h 47m

1 stop

DSM1:47 pmDes Moines

Nov 17

DSM2:32 pmDes Moines

20h 42m

2 stops

ORD11:14 amChicago O'Hare Intl

$256

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 11/6

6:00 am-1:56 pm

1 stop7h 56m

Des Moines

Sun 11/9

9:03 pm-10:42 am

1 stop13h 39m

$170

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 11/6

6:00 am-1:56 pm

1 stop7h 56m

Des Moines

Sun 11/9

9:03 pm-10:42 am

1 stop13h 39m

$174

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 11/6

11:46 am-1:16 pm

Nonstop1h 30m

Des Moines

Sun 11/9

4:02 pm-5:34 pm

Nonstop1h 32m

$189

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 11/6

11:46 am-1:16 pm

Nonstop1h 30m

Des Moines

Sun 11/9

6:40 pm-8:31 pm

Nonstop1h 51m

$190

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Mon 11/10

6:00 am-1:47 pm

1 stop7h 47m

Des Moines

Mon 11/17

2:32 pm-12:15 am

1 stop9h 43m

$191

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Sat 11/1

12:59 pm-2:19 pm

Nonstop1h 20m

Des Moines

Mon 11/3

3:15 pm-4:46 pm

Nonstop1h 31m

$194

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Tue 3/3

6:00 am-10:22 am

1 stop4h 22m

Des Moines

Wed 3/4

10:55 am-2:56 pm

1 stop4h 01m

$209

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Tue 10/28

1:25 pm-8:35 pm

1 stop7h 10m

Des Moines

Sat 11/1

3:30 pm-9:19 pm

1 stop5h 49m

$219

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Sun 10/26

6:50 am-1:52 pm

1 stop7h 02m

Des Moines

Thu 10/30

2:32 pm-12:43 am

1 stop10h 11m

$228

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 11/6

9:06 am-10:30 am

Nonstop1h 24m

Des Moines

Sun 11/9

3:15 pm-4:46 pm

Nonstop1h 31m

$251

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then January is your next best option. Flight prices from Chicago O'Hare Intl Airport to Des Moines during January average around $249.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Chicago O'Hare Intl Airport to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $239. Flights from Chicago O'Hare Intl Airport to Des Moines on a Tuesday will generally be more expensive and average around $466. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the evening. momondo users have found flights departing from Chicago O'Hare Intl Airport to Des Moines in the evening for as low as $255. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $304. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago O'Hare Intl to Des Moines flight route?

Fly from Chicago O'Hare Intl to Des Moines for the best Chicago O'Hare Intl - Des Moines flight prices

What cabin class options are available on Chicago O'Hare Intl to Des Moines flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Chicago O'Hare Intl Airport to Des Moines.

How have Chicago O'Hare Intl Airport to Des Moines flight prices changed over time?

As of October 2025, prices for Chicago O'Hare Intl Airport to Des Moines flights are approximately 144% more expensive when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Des Moines (ORD to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Des Moines

Best Price Found	$280
Fastest flight time	1h 20m
Direct flights	Mon, Wed, Thu, Fri, Sat and Sun
Airports in Des Moines	1 airport

The best one-way flight to Des Moines from Chicago O'Hare Intl Airport in the past 72 hours is $280. The best round-trip flight deal from Chicago O'Hare Intl Airport to Des Moines found on momondo in the last 72 hours is $199.

The fastest flight from Chicago O'Hare Intl Airport to Des Moines takes 1h 20m

Direct flights go from Chicago O'Hare Intl Airport to Des Moines on Monday, Wednesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.

There is 1 airport near Des Moines: Des Moines (DSM)

Search flight deals

How far is Chicago O'Hare Intl to Des Moines by plane?
A flight from Chicago O'Hare Intl to Des Moines will travel around 295.9 mi. A reasonable flight in good conditions will take 1h 20m.
When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Des Moines Airport?
Prices for flights from Chicago O'Hare Intl Airport to Des Moines Airport were last updated today.
How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Des Moines Airport?
There are 2 operators available for flights from Chicago O'Hare Intl Airport to Des Moines Airport as of October 2025.
How old do you have to be to fly from Chicago O'Hare Intl Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Chicago O'Hare Intl Airport to Des Moines?
Based on momondo bookings for flights between Chicago O'Hare Intl Airport and Des Moines, the leading plane model is Airbus A319, making up 24.71% of the total bookings. Other popular models include Boeing 737-800 with 15.92%, Canadair (Bombardier) Regional Jet 700 with 15.42%, and Embraer 175 (Enhanced Winglets) with 11.94%.
What is the most popular airline from Chicago O'Hare Intl Airport to Des Moines?
momondo data reveals that the most frequently booked airline on the route from Chicago O'Hare Intl Airport to Des Moines is United Airlines, representing 53% of all bookings. The subsequent popular airline is American Airlines at 47%.

Best airlines flying from Chicago O'Hare Intl Airport to Des Moines

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $189	Free Cancellation	Rating 7.2 11,046 reviews		Search American Airlines flights
United Airlines	PriceFrom $189	Free Cancellation	Rating 7.4 8,970 reviews		Search United Airlines flights

United Airlines Flights From Chicago O'Hare Intl Airport to Des Moines
Across 31 United Airlines flights from Chicago O'Hare Intl Airport to Des Moines this week, the average price was $286, with the best United Airlines deals starting from $189 round-trip. 8,970 users have rated United Airlines on momondo, with an average score of 7.4/10.
American Airlines Flights From Chicago O'Hare Intl Airport to Des Moines
Another popular option for Chicago O'Hare Intl Airport to Des Moines flights is American Airlines (7.2/10, 11,046 ratings). American Airlines flies from Chicago O'Hare Intl Airport to Des Moines around 32 times per week, with deals starting from $189 round-trip and rising to an average price of around $249.

West Des Moines

Ames

Ankeny

Altoona

Clive

Urbandale

Pella

Newton

Johnston

Osceola

Boone

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Chicago.

Can I find flights from Chicago to Des Moines with flexible booking policies on momondo?

Flights from Chicago to Des Moines with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Chicago.

I’m not ready to book a flight from Chicago to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Chicago to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

An easier way to manage your Des Moines trip

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Cheap flights from Chicago O'Hare Intl Airport to Des Moines from $54

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Big names and deals

Filter for what you want

Filter for what you want

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Find the cheapest flights from Chicago O'Hare Intl Airport to Des Moines

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

American Airlines flights from Chicago O'Hare Intl Airport to Des Moines

Our best American Airlines deals on Chicago O'Hare Intl Airport to Des Moines flight tickets

Frontier flights from Chicago O'Hare Intl Airport to Des Moines

Our best Frontier deals on Chicago O'Hare Intl Airport to Des Moines flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Des Moines that are best for you.

See travel insights to Des Moines from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then January is your next best option. Flight prices from Chicago O'Hare Intl Airport to Des Moines during January average around $249.

What is the cheapest day to depart on your flight to Des Moines?

What is the cheapest time of day to depart on your flight to Des Moines?

What is the cheapest Chicago O'Hare Intl to Des Moines flight route?

Fly from Chicago O'Hare Intl to Des Moines for the best Chicago O'Hare Intl - Des Moines flight prices

What cabin class options are available on Chicago O'Hare Intl to Des Moines flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Chicago O'Hare Intl Airport to Des Moines.

How have Chicago O'Hare Intl Airport to Des Moines flight prices changed over time?

As of October 2025, prices for Chicago O'Hare Intl Airport to Des Moines flights are approximately 144% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Chicago O'Hare Intl to Des Moines?

Frontier, Delta, and Southwest are the most popular carriers operating from Chicago O'Hare Intl to Des Moines

How many flights depart from Chicago O'Hare Intl Airport to Des Moines on average per day?

The number of flights available between Chicago O'Hare Intl Airport and Des Moines is 42 per day as of October 2025. The most frequent departure time is 4:00PM, with 43% of daily flights leaving in the afternoon.

How many flights depart from Chicago O'Hare Intl Airport to Des Moines on average per week?

As of October 2025, 298 flights take off from Chicago O'Hare Intl Airport and land in Des Moines each week. The most common flight departure day for this route is Mon, with 15% of weekly flights taking off on this day.

When to book flights from Chicago O'Hare Intl Airport to Des Moines

Cheap Chicago O'Hare Intl Airport to Des Moines (ORD to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Des Moines

Best Price Found

Fastest flight time

Direct flights

Airports in Des Moines

How far is Chicago O'Hare Intl to Des Moines by plane?

When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Des Moines Airport?

How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Des Moines Airport?

How old do you have to be to fly from Chicago O'Hare Intl Airport to Des Moines Airport?

What documentation or ID do you need to fly to Des Moines Airport?

What is the most popular plane model from Chicago O'Hare Intl Airport to Des Moines?

What is the most popular airline from Chicago O'Hare Intl Airport to Des Moines?

Best airlines flying from Chicago O'Hare Intl Airport to Des Moines

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Des Moines with momondo

United Airlines Flights From Chicago O'Hare Intl Airport to Des Moines

American Airlines Flights From Chicago O'Hare Intl Airport to Des Moines

Traveling to a place near Des Moines?

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Des Moines?

Can I find flights from Chicago to Des Moines with flexible booking policies on momondo?

How can momondo help me find flights from Chicago to Des Moines?

I’m not ready to book a flight from Chicago to Des Moines right now. Can momondo alert me if prices change?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

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