Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Santa Ana, California to Greenville from $179

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Greenville departing on 1/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Santa Ana, California to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:45 am - 11:59 pm
SNA
-
GSP
14h 14m2 stops
United Airlines Logo
2:51 pm - 10:08 pm
GSP
-
SNA
10h 17m2 stops
$417United Airlines
sáb., feb. 14 - mié., feb. 18
Delta Logo
9:20 pm - 9:19 am
SNA
-
GSP
8h 59m1 stop
Delta Logo
5:12 pm - 10:15 pm
GSP
-
SNA
8h 03m1 stop
$420Delta
jue., ene. 29 - dom., feb. 1
Delta Logo
9:20 pm - 9:19 am
SNA
-
GSP
8h 59m1 stop
Delta Logo
5:40 am - 11:49 am
GSP
-
SNA
9h 09m1 stop
$437Delta
vie., ene. 9 - sáb., ene. 17
Delta Logo
9:51 am - 11:55 pm
SNA
-
GSP
11h 04m2 stops
Delta Logo
5:40 am - 11:49 am
GSP
-
SNA
9h 09m1 stop
$442Delta
vie., ene. 9 - sáb., ene. 17
United Airlines Logo
9:00 am - 8:47 pm
SNA
-
GSP
8h 47m2 stops
United Airlines Logo
6:20 am - 3:10 pm
GSP
-
SNA
11h 50m2 stops
$447United Airlines
vie., ene. 9 - sáb., ene. 17
United Airlines Logo
7:50 pm - 10:16 am
SNA
-
GSP
11h 26m2 stops
United Airlines Logo
6:49 am - 11:21 am
GSP
-
SNA
7h 32m1 stop
$452United Airlines
vie., ene. 30 - dom., feb. 1
Southwest Logo
6:55 pm - 10:10 am
SNA
-
GSP
12h 15m2 stops
Southwest Logo
10:45 am - 5:25 pm
GSP
-
SNA
9h 40m2 stops
$457Southwest
vie., ene. 30 - dom., feb. 1
Southwest Logo
9:45 am - 9:40 pm
SNA
-
GSP
8h 55m2 stops
Southwest Logo
6:45 am - 1:10 pm
GSP
-
SNA
9h 25m2 stops
$467Southwest
mié., may. 13 - mié., may. 20
American Airlines Logo
8:01 pm - 8:07 am
SNA
-
GSP
9h 06m2 stops
American Airlines Logo
7:59 am - 12:14 pm
GSP
-
SNA
7h 15m1 stop
$473American Airlines
mié., may. 13 - mié., may. 20
Delta Logo
9:20 pm - 9:19 am
SNA
-
GSP
8h 59m1 stop
Delta Logo
5:12 pm - 10:15 pm
GSP
-
SNA
8h 03m1 stop
$476Delta
jue., ene. 29 - lun., feb. 2

Delta flights from Santa Ana, California to Greenville

Our best Delta deals on Santa Ana, California to Greenville flight tickets
Delta
Jan 29
SNA9:20 pmSanta Ana J. Wayne/Orange Cnty
8h 59m
1 stop
GSP9:19 amGreenville
Feb 1
GSP5:12 pmGreenville
8h 03m
1 stop
SNA10:15 pmSanta Ana J. Wayne/Orange Cnty
$420
Find similar
Delta
Jan 9
SNA9:20 pmSanta Ana J. Wayne/Orange Cnty
8h 59m
1 stop
GSP9:19 amGreenville
Jan 17
GSP5:40 amGreenville
9h 09m
1 stop
SNA11:49 amSanta Ana J. Wayne/Orange Cnty
$437
Find similar
Delta
Jan 9
SNA9:51 amSanta Ana J. Wayne/Orange Cnty
11h 04m
2 stops
GSP11:55 pmGreenville
Jan 17
GSP5:40 amGreenville
9h 09m
1 stop
SNA11:49 amSanta Ana J. Wayne/Orange Cnty
$442
Find similar

American Airlines flights from Santa Ana, California to Greenville

Our best American Airlines deals on Santa Ana, California to Greenville flight tickets
American Airlines
May 13
SNA8:01 pmSanta Ana J. Wayne/Orange Cnty
9h 06m
2 stops
GSP8:07 amGreenville
May 20
GSP7:59 amGreenville
7h 15m
1 stop
SNA12:14 pmSanta Ana J. Wayne/Orange Cnty
$473
Find similar
American Airlines
May 24
SNA8:07 amSanta Ana J. Wayne/Orange Cnty
7h 48m
1 stop
GSP6:55 pmGreenville
May 31
GSP7:57 amGreenville
9h 04m
1 stop
SNA2:01 pmSanta Ana J. Wayne/Orange Cnty
$522
Find similar
American Airlines
Jan 6
SNA9:30 amSanta Ana J. Wayne/Orange Cnty
8h 26m
1 stop
GSP8:56 pmGreenville
Jan 10
GSP6:32 amGreenville
8h 30m
1 stop
SNA12:02 pmSanta Ana J. Wayne/Orange Cnty
$567
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 23, 2025.
Use the filters below to find and compare flights from Santa Ana, California to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

sáb. 2/14

6:45 am-11:59 pm

2 stops14h 14m

Greenville

mié. 2/18

2:51 pm-10:08 pm

2 stops10h 17m

$417

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

jue. 1/29

9:20 pm-9:19 am

1 stop8h 59m

Greenville

dom. 2/1

5:12 pm-10:15 pm

1 stop8h 03m

$420

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

vie. 1/9

9:20 pm-9:19 am

1 stop8h 59m

Greenville

sáb. 1/17

5:40 am-11:49 am

1 stop9h 09m

$437

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

vie. 1/9

9:51 am-11:55 pm

2 stops11h 04m

Greenville

sáb. 1/17

5:40 am-11:49 am

1 stop9h 09m

$442

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

vie. 1/9

9:00 am-8:47 pm

2 stops8h 47m

Greenville

sáb. 1/17

6:20 am-3:10 pm

2 stops11h 50m

$447

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

vie. 1/30

7:50 pm-10:16 am

2 stops11h 26m

Greenville

dom. 2/1

6:49 am-11:21 am

1 stop7h 32m

$452

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

vie. 1/30

6:55 pm-10:10 am

2 stops12h 15m

Greenville

dom. 2/1

10:45 am-5:25 pm

2 stops9h 40m

$457

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

mié. 5/13

9:45 am-9:40 pm

2 stops8h 55m

Greenville

mié. 5/20

6:45 am-1:10 pm

2 stops9h 25m

$467

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

mié. 5/13

8:01 pm-8:07 am

2 stops9h 06m

Greenville

mié. 5/20

7:59 am-12:14 pm

1 stop7h 15m

$473

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

jue. 1/29

9:20 pm-9:19 am

1 stop8h 59m

Greenville

lun. 2/2

5:12 pm-10:15 pm

1 stop8h 03m

$476

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

See travel insights to Greenville from

How to get the cheapest flight ticket from Santa Ana, California to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of September is another great option to travel to Greenville, with average flight prices from Santa Ana, California averaging around $424.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Thursday is the cheapest day to fly to Greenville from Santa Ana, California. The lowest ticket price found for a Thursday departure recently was $122. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $307. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Santa Ana, California to Greenville during this time can be as low as $224. Flights to Greenville are more costly in the evening, with an average ticket price of $439. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on Santa Ana, California to Greenville flights?

You could potentially save up to 26% on your flight if you consider stops on a Santa Ana, California to Greenville flight.

When to book flights from Santa Ana, California to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Greenville (SNA to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Greenville

Fastest flight time

6h 11m

Direct flights

None
The fastest flight from Santa Ana, California to Greenville takes 6h 11m
There are no direct flights from Santa Ana, California to Greenville. There are no popular flight routes from Santa Ana, California to Greenville.
Search flight deals

  • How far is Santa Ana J. Wayne/Orange Cnty to Greenville by plane?

    Greenville is 2014.2 mi away from Santa Ana J. Wayne/Orange Cnty. Flights usually cover this in 6h 11m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Greenville Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Greenville Airport were last updated today.

  • How many operators does momondo search for flights from Santa Ana J. Wayne/Orange Cnty Airport to Greenville Airport?

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Ana, California to Greenville?

Best airlines flying from Santa Ana, California to Greenville

Compare and see reviews for airlines that fly from Santa Ana, California to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $324Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
DeltaPriceFrom $337Free CancellationRating
7.9
8,014 reviews
Search Delta flights
United AirlinesPriceFrom $426Free CancellationRating
7.4
9,105 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santa Ana to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santa Ana to Greenville with flexible booking policies on momondo?

Flights from Santa Ana to Greenville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santa Ana to Greenville?

momondo helps you find the best flight between Santa Ana and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santa Ana to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santa Ana to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.

An easier way to manage your Greenville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
jue. 1/22
jue. 1/29
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States