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Cheap flights from San Francisco to South America from $180

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to South America departing on 12/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
1:35 am - 4:00 pmSFO-BOG
11h 25m1 stop
Avianca Logo
4:00 am - 12:00 pmBOG-SFO
11h 00m1 stop
$444Avianca
Find Deal
Thu, Jan 29 - Fri, Mar 6
Avianca Logo
12:10 am - 11:50 amSFO-BOG
9h 40m1 stop
Avianca Logo
1:30 pm - 11:40 pmBOG-SFO
12h 10m1 stop
$446Avianca
Find Deal
Tue, Mar 10 - Tue, Mar 17
Copa Airlines Logo
12:42 am - 2:15 pmSFO-MDE
10h 33m1 stop
Copa Airlines Logo
6:20 pm - 11:20 pmMDE-SFO
32h 00m1 stop
$454Copa Airlines
Find Deal
Tue, Feb 3 - Wed, Feb 4
United Airlines Logo
1:19 pm - 5:10 amSFO-BOG
12h 51m1 stop
United Airlines Logo
8:15 am - 7:00 pmBOG-SFO
13h 45m1 stop
$459United Airlines
Find Deal
Fri, Jan 23 - Sat, Jan 31
LATAM Airlines Logo
4:02 pm - 7:30 pmSFO-BOG
24h 28m2 stops
LATAM Airlines Logo
7:00 am - 7:56 pmBOG-SFO
15h 56m2 stops
$460LATAM Airlines
Find Deal
Wed, Feb 25 - Wed, Mar 4
LATAM Airlines Logo
10:00 pm - 4:45 pmSFO-BOG
15h 45m2 stops
LATAM Airlines Logo
10:55 am - 11:37 pmBOG-SFO
15h 42m2 stops
$468LATAM Airlines
Find Deal
Wed, Jan 21 - Fri, Jan 30
Copa Airlines Logo
12:36 am - 12:20 amSFO-BOG
20h 44m1 stop
Copa Airlines Logo
10:00 am - 11:17 pmBOG-SFO
16h 17m1 stop
$469Copa Airlines
Find Deal
Sun, Dec 7 - Mon, Dec 15
United Airlines Logo
12:45 am - 9:10 pmSFO-MDE
18h 25m1 stop
United Airlines Logo
9:45 am - 10:39 pmMDE-SFO
14h 54m1 stop
$470United Airlines
Find Deal
Sat, Mar 28 - Fri, May 15
American Airlines Logo
12:17 am - 9:10 pmSFO-MDE
17h 53m2 stops
American Airlines Logo
12:20 am - 2:12 pmMDE-SFO
15h 52m2 stops
$495American Airlines
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Tue, Feb 3 - Tue, Mar 10
American Airlines Logo
12:17 am - 11:30 pmSFO-BOG
20h 13m1 stop
American Airlines Logo
11:55 pm - 5:24 pmBOG-SFO
20h 29m1 stop
$503American Airlines
Find Deal
Wed, Jan 28 - Sun, Feb 1

Copa Airlines flights from San Francisco to South America

Our best Copa Airlines deals on San Francisco to South America flight tickets
Copa Airlines
Feb 3
SFO12:42 amSan Francisco
10h 33m
1 stop
MDE2:15 pmMedellín Jose Maria Cordova Intl
Feb 4
MDE6:20 pmMedellín Jose Maria Cordova Intl
32h 00m
1 stop
SFO11:20 pmSan Francisco
$454
Find similar
Copa Airlines
Nov 17
SFO12:36 amSan Francisco
31h 31m
1 stop
BOG11:07 amBogotá El Dorado
Nov 25
BOG6:10 amBogotá El Dorado
20h 07m
1 stop
SFO11:17 pmSan Francisco
$457
Find similar
Copa Airlines
Dec 7
SFO12:36 amSan Francisco
20h 44m
1 stop
BOG12:20 amBogotá El Dorado
Dec 15
BOG10:00 amBogotá El Dorado
16h 17m
1 stop
SFO11:17 pmSan Francisco
$469
Find similar

Avianca flights from San Francisco to South America

Our best Avianca deals on San Francisco to South America flight tickets
Avianca
Jan 29
SFO1:35 amSan Francisco
11h 25m
1 stop
BOG4:00 pmBogotá El Dorado
Mar 6
BOG4:00 amBogotá El Dorado
11h 00m
1 stop
SFO12:00 pmSan Francisco
$444
Find similar
Avianca
Mar 10
SFO12:10 amSan Francisco
9h 40m
1 stop
BOG11:50 amBogotá El Dorado
Mar 17
BOG1:30 pmBogotá El Dorado
12h 10m
1 stop
SFO11:40 pmSan Francisco
$446
Find similar
Avianca
Jan 29
SFO1:35 amSan Francisco
11h 25m
1 stop
BOG4:00 pmBogotá El Dorado
Jan 31
BOG4:00 amBogotá El Dorado
11h 00m
1 stop
SFO12:00 pmSan Francisco
$447
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 10, 2025.
Use the filters below to find and compare flights from San Francisco to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 1/29

1:35 am-4:00 pm

1 stop11h 25m

Bogotá El Dorado

Fri 3/6

4:00 am-12:00 pm

1 stop11h 00m

$444

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Tue 3/10

12:10 am-11:50 am

1 stop9h 40m

Bogotá El Dorado

Tue 3/17

1:30 pm-11:40 pm

1 stop12h 10m

$446

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Tue 2/3

12:42 am-2:15 pm

1 stop10h 33m

Medellín Jose Maria Cordova Intl

Wed 2/4

6:20 pm-11:20 pm

1 stop32h 00m

$454

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Fri 1/23

1:19 pm-5:10 am

1 stop12h 51m

Bogotá El Dorado

Sat 1/31

8:15 am-7:00 pm

1 stop13h 45m

$459

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Wed 2/25

4:02 pm-7:30 pm

2 stops24h 28m

Bogotá El Dorado

Wed 3/4

7:00 am-7:56 pm

2 stops15h 56m

$460

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Wed 1/21

10:00 pm-4:45 pm

2 stops15h 45m

Bogotá El Dorado

Fri 1/30

10:55 am-11:37 pm

2 stops15h 42m

$468

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Sun 12/7

12:36 am-12:20 am

1 stop20h 44m

Bogotá El Dorado

Mon 12/15

10:00 am-11:17 pm

1 stop16h 17m

$469

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sat 3/28

12:45 am-9:10 pm

1 stop18h 25m

Medellín Jose Maria Cordova Intl

Fri 5/15

9:45 am-10:39 pm

1 stop14h 54m

$470

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Tue 2/3

12:17 am-9:10 pm

2 stops17h 53m

Medellín Jose Maria Cordova Intl

Tue 3/10

12:20 am-2:12 pm

2 stops15h 52m

$495

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Wed 1/28

12:17 am-11:30 pm

1 stop20h 13m

Bogotá El Dorado

Sun 2/1

11:55 pm-5:24 pm

1 stop20h 29m

$503

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from San Francisco to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from San Francisco to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $617. If you aren’t able to travel during the month of September, then book flights to South America from San Francisco during October instead. Flights to South America in October, while not as cheap as those in September, still average around $642.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from San Francisco to South America is on a Tuesday when prices can be found for as low as $688. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Francisco to South America for around $773.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest San Francisco to South America flights are usually those with departure times in the morning. Our users have found flights to South America in the morning for as low as $726. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $738 on average. Flights to South America from San Francisco at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $718 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from San Francisco for as low as $634 on momondo.

Can stopping save me money on San Francisco to South America flights?

You could potentially save up to 5% on your flight if you consider stops on a San Francisco to South America flight.

Cheap San Francisco to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to South America

Direct flights

None
There are no direct flights from San Francisco to South America. There are no popular flight routes from San Francisco to South America.
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  • When did momondo last update prices for flights from San Francisco Airport to South America?

    Prices for flights from San Francisco Airport to South America are updated daily.

  • How many operators does momondo search for flights from San Francisco Airport to South America?

  • How old do you have to be to fly from San Francisco Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Francisco to South America

Compare and see reviews for airlines that fly from San Francisco to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $366Free CancellationRating
7.9
8,007 reviews
Search Delta flights
AviancaPriceFrom $381Free CancellationRating
6.6
2,473 reviews
Search Avianca flights
United AirlinesPriceFrom $392Free CancellationRating
7.4
9,012 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $399Free CancellationRating
7.5
1,872 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $403Free CancellationRating
7.6
1,562 reviews
Search Copa Airlines flights
JetBluePriceFrom $409Free CancellationRating
7.2
2,907 reviews
Search JetBlue flights
American AirlinesPriceFrom $463Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights
Air CanadaPriceFrom $531Free CancellationRating
7.1
10,437 reviews
Search Air Canada flights
AeromexicoPriceFrom $652Free CancellationRating
7.4
1,672 reviews
Search Aeromexico flights
GOLPriceFrom $765Free CancellationRating
7.3
1,127 reviews
Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to South America?

It is quick and easy to find San Francisco to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from San Francisco to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Francisco to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from San Francisco to South America?

momondo provides multiple filters to help you find the best flight to South America from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
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