What is the cheapest airline that flies from San Francisco to South America?

United Airlines, Copa Airlines, and Delta are the most popular carriers operating from San Francisco to South America

What airlines fly to South America?

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to South America from San Francisco according to our data. Copa Airlines is the first choice among our users, with 33% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 10 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from San Francisco Airport to South America?

Prices for flights from San Francisco Airport to South America are updated daily.

How many operators does momondo search for flights from San Francisco Airport to South America?

There are 10 operators available for flights from San Francisco Airport to South America as of May 2026.

How old do you have to be to fly from San Francisco Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.

What documentation or ID do you need to fly to South America?

The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$161 Cheap Flights from San Francisco to South America in 2026

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Find the cheapest flights from San Francisco to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:14 am - 11:39 pm

SFO

MDE

13h 25m

2 stops

7:00 am - 8:14 pm

MDE

SFO

16h 14m

2 stops

$364American Airlines

Sun, Nov 1 - Sat, Nov 7

7:30 am - 10:57 pm

SFO

BOG

13h 27m

1 stop

11:55 pm - 9:25 am

BOG

SFO

12h 30m

1 stop

$371American Airlines

Tue, Oct 27 - Mon, Nov 2

6:30 pm - 4:54 am

SFO

BOG

32h 24m

1 stop

8:30 am - 9:45 pm

BOG

SFO

15h 15m

1 stop

$382United Airlines

Sat, Oct 17 - Wed, Oct 21

12:45 am - 7:20 pm

SFO

BOG

16h 35m

1 stop

8:30 am - 12:16 am

BOG

SFO

17h 46m

1 stop

$391United Airlines

Thu, Aug 20 - Wed, Sep 9

11:59 pm - 8:10 pm

SFO

BOG

18h 11m

2 stops

2:55 pm - 1:31 pm

BOG

SFO

24h 36m

2 stops

$400LATAM Airlines

Sat, Jul 11 - Sun, Aug 9

7:00 am - 10:10 pm

SFO

LIM

13h 10m

1 stop

12:15 am - 7:24 pm

LIM

SFO

21h 09m

2 stops

$533LATAM Airlines

Mon, Sep 14 - Mon, Sep 21

8:16 pm - 2:09 pm

SFO

UIO

15h 53m

1 stop

3:09 pm - 11:40 pm

UIO

SFO

10h 31m

1 stop

$567Copa Airlines

Wed, Jun 3 - Wed, Jun 10

8:21 pm - 7:15 pm

SFO

LIM

20h 54m

1 stop

2:35 am - 11:40 pm

LIM

SFO

23h 05m

1 stop

$568Copa Airlines

Tue, Aug 25 - Mon, Sep 21

2:15 pm - 2:55 am

SFO

UIO

10h 40m

1 stop

4:05 am - 12:50 pm

UIO

SFO

10h 45m

1 stop

$605Avianca

Mon, Aug 17 - Sat, Aug 29

11:55 pm - 12:30 am

SFO

GIG

20h 35m

2 stops

7:20 am - 10:35 pm

GIG

SFO

19h 15m

2 stops

$765Avianca

Wed, Aug 12 - Thu, Aug 27

Avianca flights from San Francisco to South America

Our best Avianca deals on San Francisco to South America flight tickets

Avianca

May 23

SFO2:15 pmSan Francisco

9h 45m

1 stop

BOG2:00 amBogotá El Dorado

Jun 1

BOG4:25 amBogotá El Dorado

10h 25m

1 stop

SFO12:50 pmSan Francisco

$573

Avianca

May 16

SFO11:55 pmSan Francisco

14h 05m

1 stop

BOG4:00 pmBogotá El Dorado

Jun 1

BOG4:25 amBogotá El Dorado

10h 25m

1 stop

SFO12:50 pmSan Francisco

$590

Avianca

May 19

SFO11:55 pmSan Francisco

14h 05m

1 stop

BOG4:00 pmBogotá El Dorado

May 26

BOG4:25 amBogotá El Dorado

10h 25m

1 stop

SFO12:50 pmSan Francisco

$597

LATAM Airlines flights from San Francisco to South America

Our best LATAM Airlines deals on San Francisco to South America flight tickets

LATAM Airlines

Jul 11

SFO11:59 pmSan Francisco

18h 11m

2 stops

BOG8:10 pmBogotá El Dorado

Aug 11

BOG11:00 amBogotá El Dorado

14h 54m

2 stops

SFO11:54 pmSan Francisco

$400

LATAM Airlines

Jun 1

SFO6:20 pmSan Francisco

22h 55m

2 stops

BOG7:15 pmBogotá El Dorado

Jun 7

BOG2:55 pmBogotá El Dorado

11h 50m

1 stop

SFO12:45 amSan Francisco

$426

LATAM Airlines

Jun 22

SFO10:59 pmSan Francisco

19h 11m

2 stops

BOG8:10 pmBogotá El Dorado

Jul 23

BOG11:00 amBogotá El Dorado

15h 36m

2 stops

SFO12:36 amSan Francisco

$431

momondo Fare Finder

Use the filters below to find and compare flights from San Francisco to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sun 11/1

7:14 am-11:39 pm

2 stops13h 25m

Medellín Jose Maria Cordova Intl

Sat 11/7

7:00 am-8:14 pm

2 stops16h 14m

$364

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Tue 10/27

7:30 am-10:57 pm

1 stop13h 27m

Bogotá El Dorado

Mon 11/2

11:55 pm-9:25 am

1 stop12h 30m

$371

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Sat 10/17

6:30 pm-4:54 am

1 stop32h 24m

Bogotá El Dorado

Wed 10/21

8:30 am-9:45 pm

1 stop15h 15m

$382

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 8/20

12:45 am-7:20 pm

1 stop16h 35m

Bogotá El Dorado

Wed 9/9

8:30 am-12:16 am

1 stop17h 46m

$391

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Sat 7/11

11:59 pm-8:10 pm

2 stops18h 11m

Bogotá El Dorado

Sun 8/9

2:55 pm-1:31 pm

2 stops24h 36m

$400

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

Mon 9/14

7:00 am-10:10 pm

1 stop13h 10m

Lima J Chavez Intl

Mon 9/21

12:15 am-7:24 pm

2 stops21h 09m

$533

San FranciscoQuito

SFO - UIO

SFOUIO

San Francisco

Wed 6/3

8:16 pm-2:09 pm

1 stop15h 53m

Quito Mariscal Sucr

Wed 6/10

3:09 pm-11:40 pm

1 stop10h 31m

$567

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

Tue 8/25

8:21 pm-7:15 pm

1 stop20h 54m

Lima J Chavez Intl

Mon 9/21

2:35 am-11:40 pm

1 stop23h 05m

$568

Quickest round-trip

San FranciscoQuito

SFO - UIO

SFOUIO

San Francisco

Mon 8/17

2:15 pm-2:55 am

1 stop10h 40m

Quito Mariscal Sucr

Sat 8/29

4:05 am-12:50 pm

1 stop10h 45m

$605

San FranciscoRio de Janeiro

SFO - GIG

SFOGIG

San Francisco

Wed 8/12

11:55 pm-12:30 am

2 stops20h 35m

Rio de Janeiro–Galeão Intl

Thu 8/27

7:20 am-10:35 pm

2 stops19h 15m

$765

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Francisco to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, May is the cheapest month to fly from San Francisco to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $577. If you aren’t able to travel during the month of May, then book flights to South America from San Francisco during April instead. Flights to South America in April, while not as cheap as those in May, still average around $599.

How far in advance should I book a flight from San Francisco to South America?

You are more likely to see cheaper flights to South America from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $691 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from San Francisco for as low as $633 on momondo.

Can stopping save me money on San Francisco to South America flights?

You could potentially save up to 10% on your flight if you consider stops on a San Francisco to South America flight.

Cheap San Francisco to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to South America

Fastest flight time	9h 45m
Direct flights	None

The fastest flight from San Francisco to South America takes 9h 45m

There are no direct flights from San Francisco to South America. There are no popular flight routes from San Francisco to South America.

Search flight deals

Frequently asked questions about flying from San Francisco to South America

When did momondo last update prices for flights from San Francisco Airport to South America?
Prices for flights from San Francisco Airport to South America are updated daily.
How many operators does momondo search for flights from San Francisco Airport to South America?
There are 10 operators available for flights from San Francisco Airport to South America as of May 2026.
How old do you have to be to fly from San Francisco Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.
What documentation or ID do you need to fly to South America?
The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Francisco to South America

Compare and see reviews for airlines that fly from San Francisco to South America with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $214	Free Cancellation	Rating 7.4 9,727 reviews	Search United Airlines flights
Delta	PriceFrom $223	Free Cancellation	Rating 7.9 8,455 reviews	Search Delta flights
LATAM Airlines	PriceFrom $234	Free Cancellation	Rating 7.4 1,923 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $271	Free Cancellation	Rating 7.5 1,584 reviews	Search Copa Airlines flights
Avianca	PriceFrom $290	Free Cancellation	Rating 6.5 2,527 reviews	Search Avianca flights
JetBlue	PriceFrom $292	Free Cancellation	Rating 7.1 2,977 reviews	Search JetBlue flights
GOL	PriceFrom $415	Free Cancellation	Rating 7.3 1,219 reviews	Search GOL flights
American Airlines	PriceFrom $459	Free Cancellation	Rating 7.1 11,662 reviews	Search American Airlines flights
Air Canada	PriceFrom $576	Free Cancellation	Rating 7.1 11,046 reviews	Search Air Canada flights
Aeromexico	PriceFrom $602	Free Cancellation	Rating 7.4 1,511 reviews	Search Aeromexico flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to South America?

It is quick and easy to find San Francisco to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from San Francisco to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Francisco to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from San Francisco to South America?

momondo provides multiple filters to help you find the best flight to South America from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.