What airlines fly to South America?

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to South America from San Francisco according to our data. Copa Airlines is the first choice among our users, with 34% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 10 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from San Francisco to South America?

United Airlines, Copa Airlines, and Azul are the most popular carriers operating from San Francisco to South America

When did momondo last update prices for flights from San Francisco Airport to South America?

Prices for flights from San Francisco Airport to South America are updated daily.

How many operators does momondo search for flights from San Francisco Airport to South America?

There are 10 operators available for flights from San Francisco Airport to South America as of May 2026.

How old do you have to be to fly from San Francisco Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.

What documentation or ID do you need to fly to South America?

The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$222 Cheap Flights from San Francisco to South America in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from San Francisco to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:14 am - 11:39 pm

SFO

MDE

13h 25m

2 stops

7:00 am - 8:14 pm

MDE

SFO

16h 14m

2 stops

$364American Airlines

Sun, Nov 1 - Sat, Nov 7

6:45 am - 10:57 pm

SFO

BOG

14h 12m

2 stops

11:45 pm - 12:37 pm

BOG

SFO

14h 52m

2 stops

$376American Airlines

Wed, Sep 9 - Mon, Sep 21

8:21 pm - 5:07 pm

SFO

BOG

18h 46m

1 stop

12:08 pm - 11:40 pm

BOG

SFO

13h 32m

1 stop

$441Copa Airlines

Thu, Aug 20 - Tue, Sep 8

4:20 pm - 10:00 pm

SFO

BOG

27h 40m

1 stop

11:10 pm - 12:14 pm

BOG

SFO

15h 04m

1 stop

$445United Airlines

Sun, Jun 14 - Mon, Jun 29

11:59 pm - 7:20 pm

SFO

BOG

17h 21m

1 stop

11:10 pm - 12:14 pm

BOG

SFO

15h 04m

1 stop

$453United Airlines

Mon, Jun 1 - Tue, Jun 30

7:21 pm - 12:31 am

SFO

UIO

26h 10m

1 stop

8:34 am - 5:28 pm

UIO

SFO

11h 54m

1 stop

$567Copa Airlines

Wed, Nov 4 - Wed, Nov 11

6:00 am - 6:59 pm

SFO

UIO

10h 59m

1 stop

9:00 am - 11:54 am

UIO

SFO

28h 54m

2 stops

$604LATAM Airlines

Tue, Oct 6 - Sun, Oct 11

1:20 pm - 2:50 am

SFO

UIO

10h 30m

1 stop

4:00 am - 12:00 pm

UIO

SFO

11h 00m

1 stop

$607Avianca

Tue, Nov 3 - Thu, Nov 12

8:55 am - 5:35 am

SFO

SCL

16h 40m

1 stop

7:45 am - 11:11 pm

SCL

SFO

19h 26m

2 stops

$675LATAM Airlines

Tue, Sep 15 - Wed, Oct 14

11:55 pm - 12:30 am

SFO

GIG

20h 35m

2 stops

7:20 am - 10:35 pm

GIG

SFO

19h 15m

2 stops

$759Avianca

Sun, Oct 4 - Sat, Oct 24

Copa Airlines flights from San Francisco to South America

Our best Copa Airlines deals on San Francisco to South America flight tickets

Copa Airlines

Aug 20

SFO8:21 pmSan Francisco

21h 49m

1 stop

BOG8:10 pmBogotá El Dorado

Sep 8

BOG6:10 amBogotá El Dorado

19h 30m

1 stop

SFO11:40 pmSan Francisco

$441

Copa Airlines

Sep 24

SFO1:12 amSan Francisco

10h 17m

1 stop

BOG1:29 pmBogotá El Dorado

Oct 10

BOG4:45 pmBogotá El Dorado

27h 25m

1 stop

SFO6:10 pmSan Francisco

$501

Copa Airlines

Aug 27

SFO1:12 amSan Francisco

31h 54m

1 stop

BOG11:06 amBogotá El Dorado

Sep 12

BOG6:17 pmBogotá El Dorado

31h 23m

1 stop

SFO11:40 pmSan Francisco

$515

United Airlines flights from San Francisco to South America

Our best United Airlines deals on San Francisco to South America flight tickets

United Airlines

May 19

SFO4:45 pmSan Francisco

24h 35m

1 stop

BOG7:20 pmBogotá El Dorado

May 25

BOG12:14 amBogotá El Dorado

33h 08m

1 stop

SFO7:22 amSan Francisco

$441

United Airlines

May 19

SFO2:28 pmSan Francisco

26h 52m

1 stop

BOG7:20 pmBogotá El Dorado

May 26

BOG8:30 amBogotá El Dorado

24h 52m

1 stop

SFO7:22 amSan Francisco

$443

United Airlines

May 19

SFO2:28 pmSan Francisco

26h 52m

1 stop

BOG7:20 pmBogotá El Dorado

May 26

BOG8:30 amBogotá El Dorado

17h 45m

1 stop

SFO12:15 amSan Francisco

$445

momondo Fare Finder

Use the filters below to find and compare flights from San Francisco to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sun 11/1

7:14 am-11:39 pm

2 stops13h 25m

Medellín Jose Maria Cordova Intl

Sat 11/7

7:00 am-8:14 pm

2 stops16h 14m

$364

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Wed 9/9

6:45 am-10:57 pm

2 stops14h 12m

Bogotá El Dorado

Mon 9/21

11:45 pm-12:37 pm

2 stops14h 52m

$376

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 8/20

8:21 pm-5:07 pm

1 stop18h 46m

Bogotá El Dorado

Tue 9/8

12:08 pm-11:40 pm

1 stop13h 32m

$441

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Sun 6/14

4:20 pm-10:00 pm

1 stop27h 40m

Bogotá El Dorado

Mon 6/29

11:10 pm-12:14 pm

1 stop15h 04m

$445

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Mon 6/1

11:59 pm-7:20 pm

1 stop17h 21m

Bogotá El Dorado

Tue 6/30

11:10 pm-12:14 pm

1 stop15h 04m

$453

San FranciscoQuito

SFO - UIO

SFOUIO

San Francisco

Wed 11/4

7:21 pm-12:31 am

1 stop26h 10m

Quito Mariscal Sucr

Wed 11/11

8:34 am-5:28 pm

1 stop11h 54m

$567

San FranciscoQuito

SFO - UIO

SFOUIO

San Francisco

Tue 10/6

6:00 am-6:59 pm

1 stop10h 59m

Quito Mariscal Sucr

Sun 10/11

9:00 am-11:54 am

2 stops28h 54m

$604

Quickest round-trip

San FranciscoQuito

SFO - UIO

SFOUIO

San Francisco

Tue 11/3

1:20 pm-2:50 am

1 stop10h 30m

Quito Mariscal Sucr

Thu 11/12

4:00 am-12:00 pm

1 stop11h 00m

$607

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Tue 9/15

8:55 am-5:35 am

1 stop16h 40m

Santiago Arturo Merino Benitez

Wed 10/14

7:45 am-11:11 pm

2 stops19h 26m

$675

San FranciscoRio de Janeiro

SFO - GIG

SFOGIG

San Francisco

Sun 10/4

11:55 pm-12:30 am

2 stops20h 35m

Rio de Janeiro–Galeão Intl

Sat 10/24

7:20 am-10:35 pm

2 stops19h 15m

$759

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Francisco to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, May is the cheapest month to fly from San Francisco to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $575. If you aren’t able to travel during the month of May, then book flights to South America from San Francisco during April instead. Flights to South America in April, while not as cheap as those in May, still average around $598.

How far in advance should I book a flight from San Francisco to South America?

You are more likely to see cheaper flights to South America from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $692 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from San Francisco for as low as $633 on momondo.

Can stopping save me money on San Francisco to South America flights?

You could potentially save up to 15% on your flight if you consider stops on a San Francisco to South America flight.

Cheap San Francisco to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to South America

Fastest flight time	9h 59m
Direct flights	None

The fastest flight from San Francisco to South America takes 9h 59m

There are no direct flights from San Francisco to South America. There are no popular flight routes from San Francisco to South America.

Search flight deals

Frequently asked questions about flying from San Francisco to South America

When did momondo last update prices for flights from San Francisco Airport to South America?
Prices for flights from San Francisco Airport to South America are updated daily.
How many operators does momondo search for flights from San Francisco Airport to South America?
There are 10 operators available for flights from San Francisco Airport to South America as of May 2026.
How old do you have to be to fly from San Francisco Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.
What documentation or ID do you need to fly to South America?
The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Francisco to South America

Compare and see reviews for airlines that fly from San Francisco to South America with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $214	Free Cancellation	Rating 7.4 9,732 reviews	Search United Airlines flights
Delta	PriceFrom $223	Free Cancellation	Rating 7.9 8,452 reviews	Search Delta flights
LATAM Airlines	PriceFrom $234	Free Cancellation	Rating 7.4 1,924 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $273	Free Cancellation	Rating 7.5 1,577 reviews	Search Copa Airlines flights
Avianca	PriceFrom $290	Free Cancellation	Rating 6.5 2,528 reviews	Search Avianca flights
JetBlue	PriceFrom $292	Free Cancellation	Rating 7.2 2,982 reviews	Search JetBlue flights
GOL	PriceFrom $415	Free Cancellation	Rating 7.3 1,222 reviews	Search GOL flights
American Airlines	PriceFrom $448	Free Cancellation	Rating 7.1 11,645 reviews	Search American Airlines flights
Air Canada	PriceFrom $576	Free Cancellation	Rating 7.1 11,062 reviews	Search Air Canada flights
Aeromexico	PriceFrom $652	Free Cancellation	Rating 7.4 1,505 reviews	Search Aeromexico flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to South America?

It is quick and easy to find San Francisco to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from San Francisco to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Francisco to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from San Francisco to South America?

momondo provides multiple filters to help you find the best flight to South America from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.