What airlines fly to South America?

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to South America from San Francisco according to our data. Copa Airlines is the first choice among our users, with 35% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 10 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from San Francisco to South America?

Copa Airlines, American Airlines, and Delta are the most popular carriers operating from San Francisco to South America

When did momondo last update prices for flights from San Francisco Airport to South America?

Prices for flights from San Francisco Airport to South America are updated daily.

How many operators does momondo search for flights from San Francisco Airport to South America?

There are 10 operators available for flights from San Francisco Airport to South America as of June 2026.

How old do you have to be to fly from San Francisco Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.

What documentation or ID do you need to fly to South America?

The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$210 Cheap Flights from San Francisco to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:21 pm - 8:05 am

SFO

CTG

9h 44m

1 stop

6:20 am - 11:40 pm

CTG

SFO

19h 20m

1 stop

$461Copa Airlines

Wed, Sep 16 - Tue, Sep 22

11:59 pm - 12:05 pm

SFO

CTG

10h 06m

1 stop

2:05 pm - 10:59 pm

CTG

SFO

10h 54m

1 stop

$473American Airlines

Mon, Oct 5 - Thu, Oct 8

2:30 am - 4:00 pm

SFO

BOG

11h 30m

1 stop

9:05 am - 10:35 pm

BOG

SFO

15h 30m

1 stop

$516Avianca

Tue, Jul 28 - Fri, Aug 21

7:45 am - 2:00 am

SFO

BOG

16h 15m

2 stops

1:40 pm - 10:35 pm

BOG

SFO

10h 55m

1 stop

$517Avianca

Thu, Jul 30 - Wed, Aug 12

7:13 am - 10:10 pm

SFO

LIM

12h 57m

1 stop

8:15 am - 11:58 pm

LIM

SFO

17h 43m

2 stops

$553LATAM Airlines

Tue, Aug 18 - Thu, Sep 3

7:13 am - 5:00 am

SFO

LIM

19h 47m

2 stops

8:15 am - 11:58 pm

LIM

SFO

17h 43m

2 stops

$558Delta

Tue, Aug 18 - Tue, Aug 25

7:13 am - 10:10 pm

SFO

LIM

12h 57m

1 stop

8:15 am - 11:58 pm

LIM

SFO

17h 43m

2 stops

$575Delta

Tue, Aug 18 - Thu, Sep 3

10:00 pm - 8:05 am

SFO

LIM

32h 05m

2 stops

1:30 pm - 3:49 pm

LIM

SFO

28h 19m

2 stops

$578LATAM Airlines

Sat, Aug 29 - Mon, Sep 14

11:59 pm - 7:50 am

SFO

SCL

27h 51m

1 stop

10:45 pm - 6:47 pm

SCL

SFO

25h 02m

1 stop

$747United Airlines

Fri, Oct 30 - Mon, Nov 16

6:00 am - 4:45 pm

SFO

SDU

30h 45m

2 stops

1:45 pm - 11:25 am

SDU

SFO

25h 40m

2 stops

$1,171United Airlines

Wed, Sep 9 - Wed, Sep 23

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Avianca flights from San Francisco to South America

Our best Avianca deals on San Francisco to South America flight tickets

Avianca

Jul 28

SFO2:30 amSan Francisco

11h 30m

1 stop

BOG4:00 pmBogotá El Dorado

Aug 21

BOG9:05 amBogotá El Dorado

15h 30m

1 stop

SFO10:35 pmSan Francisco

$516

Avianca

Jul 30

SFO7:45 amSan Francisco

16h 15m

2 stops

BOG2:00 amBogotá El Dorado

Aug 12

BOG1:40 pmBogotá El Dorado

10h 55m

1 stop

SFO10:35 pmSan Francisco

$517

Avianca

Jul 30

SFO7:45 amSan Francisco

16h 15m

2 stops

BOG2:00 amBogotá El Dorado

Aug 18

BOG9:05 amBogotá El Dorado

15h 30m

1 stop

SFO10:35 pmSan Francisco

$529

Delta flights from San Francisco to South America

Our best Delta deals on San Francisco to South America flight tickets

Delta

Aug 18

SFO7:13 amSan Francisco

19h 47m

2 stops

LIM5:00 amLima J Chavez Intl

Aug 25

LIM8:15 amLima J Chavez Intl

17h 43m

2 stops

SFO11:58 pmSan Francisco

$558

Delta

Dec 2

SFO6:50 pmSan Francisco

22h 30m

2 stops

BOG8:20 pmBogotá El Dorado

Dec 17

BOG9:00 amBogotá El Dorado

18h 15m

1 stop

SFO12:15 amSan Francisco

$570

Delta

Aug 25

SFO7:13 amSan Francisco

12h 57m

1 stop

LIM10:10 pmLima J Chavez Intl

Sep 1

LIM12:00 pmLima J Chavez Intl

12h 15m

1 stop

SFO10:15 pmSan Francisco

$582

momondo Fare Finder

Use the filters below to find and compare flights from San Francisco to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoCartagena

SFO - CTG

SFOCTG

San Francisco

Wed 9/16

8:21 pm-8:05 am

1 stop9h 44m

Cartagena Rafael Nunez

Tue 9/22

6:20 am-11:40 pm

1 stop19h 20m

$461

Quickest round-trip

San FranciscoCartagena

SFO - CTG

SFOCTG

San Francisco

Mon 10/5

11:59 pm-12:05 pm

1 stop10h 06m

Cartagena Rafael Nunez

Thu 10/8

2:05 pm-10:59 pm

1 stop10h 54m

$473

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Tue 7/28

2:30 am-4:00 pm

1 stop11h 30m

Bogotá El Dorado

Fri 8/21

9:05 am-10:35 pm

1 stop15h 30m

$516

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 7/30

7:45 am-2:00 am

2 stops16h 15m

Bogotá El Dorado

Wed 8/12

1:40 pm-10:35 pm

1 stop10h 55m

$517

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

Tue 8/18

7:13 am-10:10 pm

1 stop12h 57m

Lima J Chavez Intl

Thu 9/3

8:15 am-11:58 pm

2 stops17h 43m

$553

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

Tue 8/18

7:13 am-5:00 am

2 stops19h 47m

Lima J Chavez Intl

Tue 8/25

8:15 am-11:58 pm

2 stops17h 43m

$558

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

Tue 8/18

7:13 am-10:10 pm

1 stop12h 57m

Lima J Chavez Intl

Thu 9/3

8:15 am-11:58 pm

2 stops17h 43m

$575

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

Sat 8/29

10:00 pm-8:05 am

2 stops32h 05m

Lima J Chavez Intl

Mon 9/14

1:30 pm-3:49 pm

2 stops28h 19m

$578

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Fri 10/30

11:59 pm-7:50 am

1 stop27h 51m

Santiago Arturo Merino Benitez

Mon 11/16

10:45 pm-6:47 pm

1 stop25h 02m

$747

San FranciscoRio de Janeiro

SFO - SDU

SFOSDU

San Francisco

Wed 9/9

6:00 am-4:45 pm

2 stops30h 45m

Rio de Janeiro Santos Dumont

Wed 9/23

1:45 pm-11:25 am

2 stops25h 40m

$1,171

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Francisco to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, May is the cheapest month to fly from San Francisco to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $576. If you aren’t able to travel during the month of May, then book flights to South America from San Francisco during April instead. Flights to South America in April, while not as cheap as those in May, still average around $601.

How far in advance should I book a flight from San Francisco to South America?

You are more likely to see cheaper flights to South America from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $691 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from San Francisco for as low as $662 on momondo.

Can stopping save me money on San Francisco to South America flights?

You could potentially save up to 4% on your flight if you consider stops on a San Francisco to South America flight.

Cheap San Francisco to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to South America

Fastest flight time	9h 44m
Direct flights	None

The fastest flight from San Francisco to South America takes 9h 44m

There are no direct flights from San Francisco to South America. There are no popular flight routes from San Francisco to South America.

Search flight deals

Frequently asked questions about flying from San Francisco to South America

When did momondo last update prices for flights from San Francisco Airport to South America?
Prices for flights from San Francisco Airport to South America are updated daily.
How many operators does momondo search for flights from San Francisco Airport to South America?
There are 10 operators available for flights from San Francisco Airport to South America as of June 2026.
How old do you have to be to fly from San Francisco Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.
What documentation or ID do you need to fly to South America?
The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Francisco to South America

Compare and see reviews for airlines that fly from San Francisco to South America with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $214	Free Cancellation	Rating 7.4 9,826 reviews	Search United Airlines flights
Delta	PriceFrom $223	Free Cancellation	Rating 7.9 8,397 reviews	Search Delta flights
LATAM Airlines	PriceFrom $233	Free Cancellation	Rating 7.4 1,933 reviews	Search LATAM Airlines flights
Avianca	PriceFrom $284	Free Cancellation	Rating 6.5 2,532 reviews	Search Avianca flights
Copa Airlines	PriceFrom $286	Free Cancellation	Rating 7.5 1,570 reviews	Search Copa Airlines flights
JetBlue	PriceFrom $292	Free Cancellation	Rating 7.1 2,985 reviews	Search JetBlue flights
GOL	PriceFrom $415	Free Cancellation	Rating 7.3 1,230 reviews	Search GOL flights
American Airlines	PriceFrom $448	Free Cancellation	Rating 7.1 11,662 reviews	Search American Airlines flights
Air Canada	PriceFrom $602	Free Cancellation	Rating 7.1 11,193 reviews	Search Air Canada flights
Aeromexico	PriceFrom $652	Free Cancellation	Rating 7.4 1,487 reviews	Search Aeromexico flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to South America?

It is quick and easy to find San Francisco to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from San Francisco to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Francisco to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from San Francisco to South America?

momondo provides multiple filters to help you find the best flight to South America from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.