What airlines fly to South America?

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to South America from San Francisco according to our data. Copa Airlines is the first choice among our users, with 33% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 10 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from San Francisco to South America?

United Airlines, LATAM Airlines, and Delta are the most popular carriers operating from San Francisco to South America

When did momondo last update prices for flights from San Francisco Airport to South America?

Prices for flights from San Francisco Airport to South America are updated daily.

How many operators does momondo search for flights from San Francisco Airport to South America?

There are 10 operators available for flights from San Francisco Airport to South America as of April 2026.

How old do you have to be to fly from San Francisco Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.

What documentation or ID do you need to fly to South America?

The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$161 Cheap Flights from San Francisco to South America in 2026

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Find the cheapest flights from San Francisco to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:00 am - 8:35 pm

SFO

BOG

11h 35m

1 stop

8:40 am - 10:14 pm

BOG

SFO

15h 34m

1 stop

$347Multiple Airlines

Tue, Oct 6 - Tue, Oct 20

1:40 pm - 12:48 pm

SFO

MDE

21h 08m

2 stops

1:53 pm - 12:16 pm

MDE

SFO

24h 23m

2 stops

$360GOL

Sat, May 2 - Tue, May 12

1:16 pm - 12:48 pm

SFO

MDE

21h 32m

2 stops

11:59 pm - 10:58 pm

MDE

SFO

24h 59m

1 stop

$370GOL

Sat, May 9 - Tue, May 26

12:45 am - 9:10 pm

SFO

MDE

18h 25m

1 stop

9:45 am - 6:29 pm

MDE

SFO

10h 44m

1 stop

$373United Airlines

Sun, Aug 16 - Thu, Aug 27

7:15 am - 9:10 pm

SFO

MDE

11h 55m

1 stop

9:45 am - 7:15 am

MDE

SFO

23h 30m

1 stop

$382United Airlines

Tue, May 5 - Fri, May 8

7:15 am - 10:10 pm

SFO

LIM

12h 55m

1 stop

12:50 am - 3:56 pm

LIM

SFO

17h 06m

1 stop

$548LATAM Airlines

Thu, May 14 - Sun, May 24

6:20 pm - 8:05 am

SFO

LIM

11h 45m

1 stop

12:00 pm - 11:41 pm

LIM

SFO

13h 41m

1 stop

$551LATAM Airlines

Wed, May 27 - Fri, Jun 19

1:12 am - 5:32 pm

SFO

UIO

14h 20m

1 stop

3:07 am - 6:14 pm

UIO

SFO

17h 07m

1 stop

$605Copa Airlines

Mon, May 18 - Tue, May 26

2:15 pm - 2:55 am

SFO

UIO

10h 40m

1 stop

4:05 am - 12:50 pm

UIO

SFO

10h 45m

1 stop

$606Avianca

Mon, May 4 - Mon, May 18

2:15 pm - 2:55 am

SFO

UIO

10h 40m

1 stop

4:05 am - 12:50 pm

UIO

SFO

10h 45m

1 stop

$607Avianca

Sun, May 10 - Tue, May 19

American Airlines flights from San Francisco to South America

Our best American Airlines deals on San Francisco to South America flight tickets

American Airlines

Sep 9

SFO7:30 amSan Francisco

13h 27m

1 stop

BOG10:57 pmBogotá El Dorado

Sep 21

BOG11:45 pmBogotá El Dorado

11h 10m

1 stop

SFO8:55 amSan Francisco

$377

American Airlines

Aug 17

SFO6:36 amSan Francisco

15h 15m

2 stops

MDE11:51 pmMedellín Jose Maria Cordova Intl

Aug 27

MDE12:30 amMedellín Jose Maria Cordova Intl

12h 04m

1 stop

SFO10:34 amSan Francisco

$378

American Airlines

Sep 9

SFO6:45 amSan Francisco

14h 12m

2 stops

BOG10:57 pmBogotá El Dorado

Sep 21

BOG11:45 pmBogotá El Dorado

14h 52m

2 stops

SFO12:37 pmSan Francisco

$388

Delta flights from San Francisco to South America

Our best Delta deals on San Francisco to South America flight tickets

Delta

May 16

SFO11:59 pmSan Francisco

17h 16m

1 stop

BOG7:15 pmBogotá El Dorado

Jun 2

BOG8:40 amBogotá El Dorado

15h 43m

2 stops

SFO10:23 pmSan Francisco

$386

Delta

Sep 8

SFO6:00 amSan Francisco

11h 15m

1 stop

BOG7:15 pmBogotá El Dorado

Sep 22

BOG10:35 amBogotá El Dorado

15h 17m

2 stops

SFO11:52 pmSan Francisco

$389

Delta

May 11

SFO11:59 pmSan Francisco

17h 16m

1 stop

BOG7:15 pmBogotá El Dorado

May 27

BOG8:40 amBogotá El Dorado

17h 10m

2 stops

SFO11:50 pmSan Francisco

$400

momondo Fare Finder

Use the filters below to find and compare flights from San Francisco to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Tue 10/6

7:00 am-8:35 pm

1 stop11h 35m

Bogotá El Dorado

Tue 10/20

8:40 am-10:14 pm

1 stop15h 34m

$347

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sat 5/2

1:40 pm-12:48 pm

2 stops21h 08m

Medellín Jose Maria Cordova Intl

Tue 5/12

1:53 pm-12:16 pm

2 stops24h 23m

$360

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sat 5/9

1:16 pm-12:48 pm

2 stops21h 32m

Medellín Jose Maria Cordova Intl

Tue 5/26

11:59 pm-10:58 pm

1 stop24h 59m

$370

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sun 8/16

12:45 am-9:10 pm

1 stop18h 25m

Medellín Jose Maria Cordova Intl

Thu 8/27

9:45 am-6:29 pm

1 stop10h 44m

$373

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Tue 5/5

7:15 am-9:10 pm

1 stop11h 55m

Medellín Jose Maria Cordova Intl

Fri 5/8

9:45 am-7:15 am

1 stop23h 30m

$382

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

Thu 5/14

7:15 am-10:10 pm

1 stop12h 55m

Lima J Chavez Intl

Sun 5/24

12:50 am-3:56 pm

1 stop17h 06m

$548

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

Wed 5/27

6:20 pm-8:05 am

1 stop11h 45m

Lima J Chavez Intl

Fri 6/19

12:00 pm-11:41 pm

1 stop13h 41m

$551

San FranciscoQuito

SFO - UIO

SFOUIO

San Francisco

Mon 5/18

1:12 am-5:32 pm

1 stop14h 20m

Quito Mariscal Sucr

Tue 5/26

3:07 am-6:14 pm

1 stop17h 07m

$605

Quickest round-trip

San FranciscoQuito

SFO - UIO

SFOUIO

San Francisco

Mon 5/4

2:15 pm-2:55 am

1 stop10h 40m

Quito Mariscal Sucr

Mon 5/18

4:05 am-12:50 pm

1 stop10h 45m

$606

San FranciscoQuito

SFO - UIO

SFOUIO

San Francisco

Sun 5/10

2:15 pm-2:55 am

1 stop10h 40m

Quito Mariscal Sucr

Tue 5/19

4:05 am-12:50 pm

1 stop10h 45m

$607

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Francisco to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from San Francisco to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $612. If you aren’t able to travel during the month of February, then book flights to South America from San Francisco during September instead. Flights to South America in September, while not as cheap as those in February, still average around $633.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $691 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from San Francisco for as low as $649 on momondo.

Can stopping save me money on San Francisco to South America flights?

You could potentially save up to 19% on your flight if you consider stops on a San Francisco to South America flight.

Cheap San Francisco to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to South America

Fastest flight time	10h 14m
Direct flights	None

The fastest flight from San Francisco to South America takes 10h 14m

There are no direct flights from San Francisco to South America. There are no popular flight routes from San Francisco to South America.

Search flight deals

Frequently asked questions about flying from San Francisco to South America

When did momondo last update prices for flights from San Francisco Airport to South America?
Prices for flights from San Francisco Airport to South America are updated daily.
How many operators does momondo search for flights from San Francisco Airport to South America?
There are 10 operators available for flights from San Francisco Airport to South America as of April 2026.
How old do you have to be to fly from San Francisco Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.
What documentation or ID do you need to fly to South America?
The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Francisco to South America

Compare and see reviews for airlines that fly from San Francisco to South America with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $214	Free Cancellation	Rating 7.4 9,613 reviews	Search United Airlines flights
Delta	PriceFrom $223	Free Cancellation	Rating 7.9 8,434 reviews	Search Delta flights
LATAM Airlines	PriceFrom $234	Free Cancellation	Rating 7.4 1,910 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $269	Free Cancellation	Rating 7.5 1,580 reviews	Search Copa Airlines flights
Avianca	PriceFrom $290	Free Cancellation	Rating 6.5 2,514 reviews	Search Avianca flights
JetBlue	PriceFrom $373	Free Cancellation	Rating 7.2 2,948 reviews	Search JetBlue flights
GOL	PriceFrom $415	Free Cancellation	Rating 7.3 1,204 reviews	Search GOL flights
American Airlines	PriceFrom $459	Free Cancellation	Rating 7.1 11,646 reviews	Search American Airlines flights
Air Canada	PriceFrom $565	Free Cancellation	Rating 7.1 10,947 reviews	Search Air Canada flights
Aeromexico	PriceFrom $652	Free Cancellation	Rating 7.4 1,541 reviews	Search Aeromexico flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to South America?

It is quick and easy to find San Francisco to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from San Francisco to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Francisco to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from San Francisco to South America?

momondo provides multiple filters to help you find the best flight to South America from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.