Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from San Francisco to South America from $148

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to South America departing on 1/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from San Francisco to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:40 am - 10:35 pmSFO-BOG
13h 55m1 stop
United Airlines Logo
8:15 am - 10:58 pmBOG-SFO
17h 43m1 stop
$450United Airlines
Find Deal
Wed, Feb 4 - Fri, Feb 20
LATAM Airlines Logo
9:30 pm - 7:30 pmSFO-BOG
19h 00m1 stop
LATAM Airlines Logo
8:35 am - 7:54 pmBOG-SFO
14h 19m2 stops
$453LATAM Airlines
Find Deal
Thu, Feb 19 - Tue, Feb 24
Delta Logo
6:45 pm - 4:45 pmSFO-BOG
19h 00m2 stops
Delta Logo
3:55 pm - 10:34 amBOG-SFO
21h 39m1 stop
$454Delta
Find Deal
Thu, Feb 5 - Mon, Feb 23
Avianca Logo
1:35 am - 4:00 pmSFO-BOG
11h 25m1 stop
Avianca Logo
4:00 am - 12:00 pmBOG-SFO
11h 00m1 stop
$457Avianca
Find Deal
Thu, Feb 5 - Fri, Feb 20
Avianca Logo
1:35 am - 4:00 pmSFO-BOG
11h 25m1 stop
Avianca Logo
9:10 am - 9:50 pmBOG-SFO
15h 40m1 stop
$461Avianca
Find Deal
Sat, Feb 14 - Sun, Feb 22
Delta Logo
6:00 am - 12:05 pmSFO-BOG
27h 05m2 stops
Delta Logo
5:00 am - 11:25 pmBOG-SFO
21h 25m2 stops
$463Delta
Find Deal
Tue, Jan 27 - Fri, Jan 30
American Airlines Logo
7:00 am - 8:15 amSFO-SCL
20h 15m2 stops
American Airlines Logo
10:30 pm - 7:12 pmSCL-SFO
25h 42m1 stop
$499American Airlines
Find Deal
Mon, Jan 12 - Mon, Feb 2
Copa Airlines Logo
1:54 am - 3:58 amSFO-SCL
22h 04m1 stop
Copa Airlines Logo
3:35 am - 11:40 pmSCL-SFO
24h 05m1 stop
$502Copa Airlines
Find Deal
Mon, Mar 23 - Mon, Mar 30
American Airlines Logo
12:17 am - 8:15 amSFO-SCL
26h 58m1 stop
American Airlines Logo
10:35 pm - 9:26 pmSCL-SFO
27h 51m1 stop
$506American Airlines
Find Deal
Sun, Jan 11 - Mon, Feb 9
Copa Airlines Logo
1:23 am - 11:26 pmSFO-SCL
19h 03m1 stop
Copa Airlines Logo
12:38 am - 11:40 pmSCL-SFO
26h 02m1 stop
$522Copa Airlines
Find Deal
Sun, Apr 19 - Sun, May 3

United Airlines flights from San Francisco to South America

Our best United Airlines deals on San Francisco to South America flight tickets
United Airlines
Feb 4
SFO5:40 amSan Francisco
13h 55m
1 stop
BOG10:35 pmBogotá El Dorado
Feb 20
BOG8:15 amBogotá El Dorado
17h 43m
1 stop
SFO10:58 pmSan Francisco
$450
Find similar
United Airlines
Mar 3
SFO7:18 amSan Francisco
12h 17m
1 stop
BOG10:35 pmBogotá El Dorado
Mar 31
BOG8:30 amBogotá El Dorado
17h 24m
1 stop
SFO11:54 pmSan Francisco
$459
Find similar
United Airlines
Dec 11
SFO7:10 pmSan Francisco
23h 55m
1 stop
MDE10:05 pmMedellín Jose Maria Cordova Intl
Dec 15
MDE1:15 amMedellín Jose Maria Cordova Intl
16h 39m
1 stop
SFO2:54 pmSan Francisco
$463
Find similar

LATAM Airlines flights from San Francisco to South America

Our best LATAM Airlines deals on San Francisco to South America flight tickets
LATAM Airlines
Feb 19
SFO9:30 pmSan Francisco
19h 00m
1 stop
BOG7:30 pmBogotá El Dorado
Feb 24
BOG8:35 amBogotá El Dorado
14h 19m
2 stops
SFO7:54 pmSan Francisco
$453
Find similar
LATAM Airlines
Mar 4
SFO6:00 amSan Francisco
10h 30m
1 stop
BOG7:30 pmBogotá El Dorado
Mar 11
BOG7:00 amBogotá El Dorado
15h 23m
2 stops
SFO8:23 pmSan Francisco
$460
Find similar
LATAM Airlines
Mar 22
SFO10:35 pmSan Francisco
13h 58m
1 stop
BOG2:33 pmBogotá El Dorado
Mar 26
BOG3:55 pmBogotá El Dorado
25h 08m
2 stops
SFO3:03 pmSan Francisco
$468
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 1, 2025.
Use the filters below to find and compare flights from San Francisco to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Wed 2/4

5:40 am-10:35 pm

1 stop13h 55m

Bogotá El Dorado

Fri 2/20

8:15 am-10:58 pm

1 stop17h 43m

$450

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 2/19

9:30 pm-7:30 pm

1 stop19h 00m

Bogotá El Dorado

Tue 2/24

8:35 am-7:54 pm

2 stops14h 19m

$453

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 2/5

6:45 pm-4:45 pm

2 stops19h 00m

Bogotá El Dorado

Mon 2/23

3:55 pm-10:34 am

1 stop21h 39m

$454

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 2/5

1:35 am-4:00 pm

1 stop11h 25m

Bogotá El Dorado

Fri 2/20

4:00 am-12:00 pm

1 stop11h 00m

$457

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Sat 2/14

1:35 am-4:00 pm

1 stop11h 25m

Bogotá El Dorado

Sun 2/22

9:10 am-9:50 pm

1 stop15h 40m

$461

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Tue 1/27

6:00 am-12:05 pm

2 stops27h 05m

Bogotá El Dorado

Fri 1/30

5:00 am-11:25 pm

2 stops21h 25m

$463

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Mon 1/12

7:00 am-8:15 am

2 stops20h 15m

Santiago Arturo Merino Benitez

Mon 2/2

10:30 pm-7:12 pm

1 stop25h 42m

$499

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Mon 3/23

1:54 am-3:58 am

1 stop22h 04m

Santiago Arturo Merino Benitez

Mon 3/30

3:35 am-11:40 pm

1 stop24h 05m

$502

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Sun 1/11

12:17 am-8:15 am

1 stop26h 58m

Santiago Arturo Merino Benitez

Mon 2/9

10:35 pm-9:26 pm

1 stop27h 51m

$506

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Sun 4/19

1:23 am-11:26 pm

1 stop19h 03m

Santiago Arturo Merino Benitez

Sun 5/3

12:38 am-11:40 pm

1 stop26h 02m

$522

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

How to get the cheapest flight ticket from San Francisco to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from San Francisco to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $616. If you aren’t able to travel during the month of September, then book flights to South America from San Francisco during October instead. Flights to South America in October, while not as cheap as those in September, still average around $642.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from San Francisco to South America is on a Tuesday when prices can be found for as low as $688. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Francisco to South America for around $773.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest San Francisco to South America flights are usually those with departure times in the morning. Our users have found flights to South America in the morning for as low as $726. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $738 on average. Flights to South America from San Francisco at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $714 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from San Francisco for as low as $634 on momondo.

Can stopping save me money on San Francisco to South America flights?

You could potentially save up to 11% on your flight if you consider stops on a San Francisco to South America flight.

Cheap San Francisco to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to South America

Fastest flight time

9h 30m

Direct flights

None
The fastest flight from San Francisco to South America takes 9h 30m
There are no direct flights from San Francisco to South America. There are no popular flight routes from San Francisco to South America.
Search flight deals

  • When did momondo last update prices for flights from San Francisco Airport to South America?

    Prices for flights from San Francisco Airport to South America are updated daily.

  • How many operators does momondo search for flights from San Francisco Airport to South America?

  • How old do you have to be to fly from San Francisco Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Francisco to South America

Compare and see reviews for airlines that fly from San Francisco to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $366Free CancellationRating
7.9
8,010 reviews
Search Delta flights
AviancaPriceFrom $381Free CancellationRating
6.6
2,475 reviews
Search Avianca flights
United AirlinesPriceFrom $392Free CancellationRating
7.4
9,065 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $402Free CancellationRating
7.6
1,560 reviews
Search Copa Airlines flights
JetBluePriceFrom $409Free CancellationRating
7.2
2,904 reviews
Search JetBlue flights
LATAM AirlinesPriceFrom $420Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $463Free CancellationRating
7.2
11,041 reviews
Search American Airlines flights
Air CanadaPriceFrom $531Free CancellationRating
7.1
10,493 reviews
Search Air Canada flights
AeromexicoPriceFrom $652Free CancellationRating
7.4
1,653 reviews
Search Aeromexico flights
GOLPriceFrom $747Free CancellationRating
7.3
1,131 reviews
Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to South America?

It is quick and easy to find San Francisco to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from San Francisco to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Francisco to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from San Francisco to South America?

momondo provides multiple filters to help you find the best flight to South America from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 12/31
Wed 1/7
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $282
Flights to Buenos Airesfrom $459
Flights to Bogotáfrom $200
Flights to Sao Paulofrom $344
Flights to Rio de Janeirofrom $396
Flights to Medellínfrom $165
Flights to Santiagofrom $334
Flights to Cartagenafrom $182
Flights to Quitofrom $266
Flights to Cuscofrom $375
Flights to Guayaquilfrom $204
Flights to Califrom $202