Cheap flights from San Francisco to South America

Round-trip
1 adult
Economy
From?
To?
Tue 9/21
Tue 9/28

Flight information for San Francisco to South America

Find info about flight duration, direct flights, and airports for your flight from San Francisco to South America
Fastest flight time9h 30mThe fastest flight from San Francisco to South America takes 9h 30m
Direct flightsNoneThere are no direct flights from San Francisco to South America. Popular non-direct routes for this connection are San Francisco Airport - Sao Paulo Guarulhos Intl Airport, San Francisco Airport - Medellín Jose Maria Cordova Intl Airport and San Francisco Airport - Lima J Chavez Intl Airport.

How to get the cheapest flight ticket from San Francisco to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies to South America from San Francisco?

Interjet

Aeromexico, Avianca, and Interjet are the most popular carriers operating from San Francisco to South America

What is the cheapest San Francisco to South America flight route?

San Francisco - Medellín Jose Maria Cordova Intl

Fly from San Francisco to Medellín Jose Maria Cordova Intl for the best San Francisco - South America flight prices


Easily compare round-trip flights from San Francisco to South America

Below you can see the best fares for your round-trip flight route over the next three months. All fares were found on momondo this week. Browse the quickest and cheapest flights from San Francisco to South America by changing tabs
Multiple Airlines
Oct 5
SFO8:49 pmSan Francisco
41h 22m
2 stops
MDE2:11 pmMedellín Jose Maria Cordova Intl
Oct 12
MDE9:20 pmMedellín Jose Maria Cordova Intl
32h 21m
2 stops
SFO5:41 amSan Francisco
Copa Airlines
Nov 1
SFO9:14 pmSan Francisco
33h 24m
1 stop
LIM6:38 amLima J Chavez Intl
Nov 16
LIM11:15 amLima J Chavez Intl
33h 50m
1 stop
SFO9:05 pmSan Francisco
Multiple Airlines
Oct 8
SFO8:51 pmSan Francisco
58h 09m
3 stops
MDE7:00 amMedellín Jose Maria Cordova Intl
Oct 29
MDE3:08 pmMedellín Jose Maria Cordova Intl
44h 15m
3 stops
SFO11:23 amSan Francisco
Copa Airlines
Nov 3
SFO9:14 pmSan Francisco
16h 06m
1 stop
LIM1:20 pmLima J Chavez Intl
Nov 10
LIM1:50 amLima J Chavez Intl
19h 15m
1 stop
SFO9:05 pmSan Francisco
Multiple Airlines
Sep 28
SFO1:06 pmSan Francisco
16h 08m
2 stops
MDE5:14 amMedellín Jose Maria Cordova Intl
Oct 12
MDE10:04 amMedellín Jose Maria Cordova Intl
21h 32m
2 stops
SFO7:36 amSan Francisco
Copa Airlines
Nov 2
SFO9:14 pmSan Francisco
33h 24m
1 stop
LIM6:38 amLima J Chavez Intl
Nov 30
LIM11:15 amLima J Chavez Intl
34h 03m
1 stop
SFO9:18 pmSan Francisco

Find the cheapest one-way flights from San Francisco to South America

If you're looking for one-way flights from San Francisco to South America, view some of our deals below.
Multiple Airlines
Sep 28
SFO8:49 pmSan Francisco
34h 11m
3 stops
BOG7:00 amBogotá El Dorado
Multiple Airlines
Sep 29
SFO12:42 pmSan Francisco
17h 58m
2 stops
BOG6:40 amBogotá El Dorado
Multiple Airlines
Oct 12
SFO10:06 amSan Francisco
21h 04m
2 stops
BOG7:10 amBogotá El Dorado

Search last-minute flights to South America from San Francisco

Find and compare flight prices for your last-minute flight from San Francisco to South America
Multiple Airlines
Sep 21
SFO1:06 pmSan Francisco
16h 08m
2 stops
MDE5:14 amMedellín Jose Maria Cordova Intl
Oct 6
MDE9:44 amMedellín Jose Maria Cordova Intl
25h 39m
2 stops
SFO11:23 amSan Francisco
Avianca
Sep 23
SFO9:30 amSan Francisco
15h 35m
1 stop
BOG1:05 amBogotá El Dorado
Nov 14
BOG11:35 pmBogotá El Dorado
10h 20m
1 stop
SFO9:55 amSan Francisco
Multiple Airlines
Sep 22
SFO12:42 pmSan Francisco
17h 53m
2 stops
MDE6:35 amMedellín Jose Maria Cordova Intl
Sep 29
MDE8:13 amMedellín Jose Maria Cordova Intl
21h 34m
2 stops
SFO5:47 amSan Francisco
Multiple Airlines
Sep 22
SFO12:42 pmSan Francisco
18h 18m
2 stops
BOG7:00 amBogotá El Dorado
Oct 6
BOG6:00 amBogotá El Dorado
23h 41m
2 stops
SFO5:41 amSan Francisco
Avianca
Sep 23
SFO9:30 amSan Francisco
15h 35m
1 stop
BOG1:05 amBogotá El Dorado
Nov 15
BOG8:40 amBogotá El Dorado
13h 29m
1 stop
SFO10:09 pmSan Francisco
Multiple Airlines
Sep 21
SFO1:06 pmSan Francisco
16h 08m
2 stops
MDE5:14 amMedellín Jose Maria Cordova Intl
Sep 23
MDE9:35 amMedellín Jose Maria Cordova Intl
20h 48m
2 stops
SFO6:23 amSan Francisco

Best airlines flying from San Francisco to South America

Compare and see reviews for airlines that fly from San Francisco to South America with momondo
AirlineRatingFree CancellationPrice
Interjet
PriceFrom $256
Free Cancellation
Rating
6.8
6.9

Boarding

7.0

Comfort

7.5

Crew

5.8

Entertainment

6.5

Food

Reviews

Pros: I was really happy with the over all flight. Everything was fast and smooth

1 / 10
Aeromexico
PriceFrom $392
Free Cancellation
Rating
7.6
7.4

Boarding

7.6

Comfort

8.3

Crew

7.5

Entertainment

7.2

Food

Reviews

EVERYTHING WAS VERY GOOD

1 / 10
Copa Airlines
PriceFrom $415
Free Cancellation
Rating
7.9
8.2

Boarding

7.8

Comfort

8.3

Crew

7.4

Entertainment

7.7

Food

Reviews

I like that I have the whole line for me; didn’t have passengers seated next to me Could improve the service on board, like food could be served a little warm instead of a cold sandwich and offer more than a round of sotf drinks

1 / 10
LATAM Airlines
PriceFrom $416
Free Cancellation
Rating
7.5
7.5

Boarding

7.3

Comfort

8.0

Crew

7.2

Entertainment

6.9

Food

Reviews

Clean and “new plane” compared to my preview’s experiene. Thank ypu

1 / 10
United Airlines
PriceFrom $427
Free Cancellation
Rating
6.8
7.2

Boarding

6.6

Comfort

7.5

Crew

6.6

Entertainment

6.1

Food

Reviews

Not because the flight is going to Africa we can’t get better service on board

1 / 10
American Airlines
PriceFrom $427
Free Cancellation
Rating
7.2
7.4

Boarding

7.1

Comfort

7.8

Crew

7.1

Entertainment

6.8

Food

Reviews

Flight attendant for first class is definitely not a morning person. Oh and the WiFi DID NOT WORK!

1 / 10
Delta
PriceFrom $433
Free Cancellation
Rating
8.3
8.3

Boarding

8.5

Comfort

8.4

Crew

8.1

Entertainment

8.1

Food

Reviews

Great

1 / 10
Avianca
PriceFrom $463
Free Cancellation
Rating
8.5
8.4

Boarding

8.5

Comfort

8.8

Crew

8.2

Entertainment

8.1

Food

Reviews

Orden y organización

1 / 10
JetBlue
PriceFrom $552
Free Cancellation
Rating
7.0
7.3

Boarding

7.6

Comfort

7.9

Crew

7.2

Entertainment

6.8

Food

Reviews

Although Westchester Airport is smaller than others I love the convenience of location. Flight was great…got in about 20 min. ahead of schedule w/minimal turbulence. Only real downside is that none of the tv’s/airline wi-fi worked so unable to watch tv or movies.

1 / 10
LATAM Airlines Brasil
PriceFrom $591
Free Cancellation
Rating
7.6
8.0

Boarding

7.1

Comfort

8.8

Crew

7.5

Entertainment

6.3

Food

Reviews

Pros: Everything

Cons: Nothing

1 / 4

  • Are airlines flying from San Francisco to South America offering flexible cancellation due to COVID-19?

    Due to the global impact of COVID-19, some of our airline partners operating flights from San Francisco to South America, such as Copa Airlines, American Airlines, and Aeromexico may have put in place flexible cancellation policies. Use our site to search for all of the airlines offering this flexibility to you.


Alternative routes for San Francisco to South America

Compare alternative flights to and from nearby airports and cities to discover the best prices and most convenient flight times
Los Angeles to Bogotá Flights
Fastest flight time6h 45m
Cheapest price$179
Los Angeles to Medellín Flights
Fastest flight time10h 37m
Cheapest price$191
Los Angeles to Guayaquil Flights
Fastest flight time10h 09m
Cheapest price$197
Los Angeles to Cartagena Flights
Fastest flight time8h 19m
Cheapest price$204
San Francisco to Medellín Flights
Fastest flight time12h 04m
Cheapest price$295
Los Angeles to Lima Flights
Fastest flight time8h 35m
Cheapest price$313
San Francisco to Bogotá Flights
Fastest flight time10h 38m
Cheapest price$334
San Francisco to Lima Flights
Fastest flight time12h 30m
Cheapest price$363
Los Angeles to Quito Flights
Fastest flight time11h 20m
Cheapest price$369
San Francisco to Cartagena Flights
Fastest flight time9h 46m
Cheapest price$403
Los Angeles to Santiago Flights
Fastest flight time10h 25m
Cheapest price$406
San Francisco to Quito Flights
Fastest flight time9h 30m
Cheapest price$440