What airlines fly to South America?

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to South America from San Francisco according to our data. Copa Airlines is the first choice among our users, with 34% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 10 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from San Francisco to South America?

Copa Airlines, JetBlue, and United Airlines are the most popular carriers operating from San Francisco to South America

When did momondo last update prices for flights from San Francisco Airport to South America?

Prices for flights from San Francisco Airport to South America are updated daily.

How many operators does momondo search for flights from San Francisco Airport to South America?

There are 10 operators available for flights from San Francisco Airport to South America as of July 2026.

How old do you have to be to fly from San Francisco Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.

What documentation or ID do you need to fly to South America?

The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$217 Cheap Flights from San Francisco to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:59 am - 11:35 am

SFO

CTG

22h 36m

1 stop

2:00 pm - 11:19 pm

CTG

SFO

11h 19m

1 stop

$482JetBlue

Sat, Aug 29 - Fri, Sep 11

6:00 am - 11:30 pm

SFO

BOG

14h 30m

1 stop

11:55 pm - 9:26 am

BOG

SFO

12h 31m

1 stop

$499American Airlines

Thu, Dec 3 - Thu, Dec 10

2:15 pm - 2:00 am

SFO

BOG

9h 45m

1 stop

1:40 pm - 10:35 pm

BOG

SFO

10h 55m

1 stop

$550Avianca

Mon, Aug 31 - Mon, Sep 14

11:55 pm - 4:00 pm

SFO

BOG

14h 05m

1 stop

4:25 am - 12:50 pm

BOG

SFO

10h 25m

1 stop

$552Avianca

Mon, Aug 3 - Wed, Aug 19

8:21 pm - 11:06 am

SFO

BOG

12h 45m

1 stop

6:17 pm - 11:40 pm

BOG

SFO

31h 23m

1 stop

$566Copa Airlines

Thu, Aug 27 - Wed, Sep 9

8:21 pm - 10:55 am

SFO

MDE

12h 34m

1 stop

3:10 pm - 11:40 pm

MDE

SFO

10h 30m

1 stop

$627Copa Airlines

Thu, Sep 10 - Thu, Sep 17

1:00 pm - 8:05 am

SFO

LIM

16h 05m

1 stop

12:15 am - 3:08 pm

LIM

SFO

17h 53m

2 stops

$648LATAM Airlines

Fri, Jan 1 - Wed, Feb 3

7:05 am - 4:00 am

SFO

SCL

16h 55m

2 stops

6:30 am - 10:07 pm

SCL

SFO

20h 37m

2 stops

$648LATAM Airlines

Mon, Oct 26 - Wed, Nov 4

7:05 am - 8:15 am

SFO

GIG

21h 10m

1 stop

9:05 pm - 11:39 am

GIG

SFO

18h 34m

1 stop

$751United Airlines

Wed, Sep 9 - Mon, Sep 14

6:30 pm - 8:15 am

SFO

GIG

33h 45m

1 stop

9:05 pm - 2:49 pm

GIG

SFO

21h 44m

1 stop

$762United Airlines

Wed, Aug 12 - Thu, Aug 27

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Avianca flights from San Francisco to South America

Our best Avianca deals on San Francisco to South America flight tickets

Avianca

Aug 31

SFO2:15 pmSan Francisco

9h 45m

1 stop

BOG2:00 amBogotá El Dorado

Sep 14

BOG1:40 pmBogotá El Dorado

10h 55m

1 stop

SFO10:35 pmSan Francisco

$550

Avianca

Aug 3

SFO11:55 pmSan Francisco

14h 05m

1 stop

BOG4:00 pmBogotá El Dorado

Aug 19

BOG4:25 amBogotá El Dorado

10h 25m

1 stop

SFO12:50 pmSan Francisco

$552

Avianca

Aug 19

SFO2:15 pmSan Francisco

9h 45m

1 stop

BOG2:00 amBogotá El Dorado

Aug 24

BOG1:40 pmBogotá El Dorado

10h 55m

1 stop

SFO10:35 pmSan Francisco

$555

LATAM Airlines flights from San Francisco to South America

Our best LATAM Airlines deals on San Francisco to South America flight tickets

LATAM Airlines

Aug 18

SFO11:15 pmSan Francisco

16h 35m

2 stops

BOG5:50 pmBogotá El Dorado

Sep 28

BOG8:40 amBogotá El Dorado

17h 18m

2 stops

SFO11:58 pmSan Francisco

$570

LATAM Airlines

Aug 20

SFO10:00 pmSan Francisco

17h 50m

2 stops

BOG5:50 pmBogotá El Dorado

Aug 27

BOG11:00 amBogotá El Dorado

14h 58m

2 stops

SFO11:58 pmSan Francisco

$591

LATAM Airlines

Jan 1

SFO1:00 pmSan Francisco

16h 05m

1 stop

LIM8:05 amLima J Chavez Intl

Feb 3

LIM12:15 amLima J Chavez Intl

17h 53m

2 stops

SFO3:08 pmSan Francisco

$648

momondo Fare Finder

Use the filters below to find and compare flights from San Francisco to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoCartagena

SFO - CTG

SFOCTG

San Francisco

Sat 8/29

10:59 am-11:35 am

1 stop22h 36m

Cartagena Rafael Nunez

Fri 9/11

2:00 pm-11:19 pm

1 stop11h 19m

$482

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 12/3

6:00 am-11:30 pm

1 stop14h 30m

Bogotá El Dorado

Thu 12/10

11:55 pm-9:26 am

1 stop12h 31m

$499

Quickest round-trip

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Mon 8/31

2:15 pm-2:00 am

1 stop9h 45m

Bogotá El Dorado

Mon 9/14

1:40 pm-10:35 pm

1 stop10h 55m

$550

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Mon 8/3

11:55 pm-4:00 pm

1 stop14h 05m

Bogotá El Dorado

Wed 8/19

4:25 am-12:50 pm

1 stop10h 25m

$552

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 8/27

8:21 pm-11:06 am

1 stop12h 45m

Bogotá El Dorado

Wed 9/9

6:17 pm-11:40 pm

1 stop31h 23m

$566

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Thu 9/10

8:21 pm-10:55 am

1 stop12h 34m

Medellín Jose Maria Cordova Intl

Thu 9/17

3:10 pm-11:40 pm

1 stop10h 30m

$627

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

Fri 1/1

1:00 pm-8:05 am

1 stop16h 05m

Lima J Chavez Intl

Wed 2/3

12:15 am-3:08 pm

2 stops17h 53m

$648

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Mon 10/26

7:05 am-4:00 am

2 stops16h 55m

Santiago Arturo Merino Benitez

Wed 11/4

6:30 am-10:07 pm

2 stops20h 37m

$648

San FranciscoRio de Janeiro

SFO - GIG

SFOGIG

San Francisco

Wed 9/9

7:05 am-8:15 am

1 stop21h 10m

Rio de Janeiro–Galeão Intl

Mon 9/14

9:05 pm-11:39 am

1 stop18h 34m

$751

San FranciscoRio de Janeiro

SFO - GIG

SFOGIG

San Francisco

Wed 8/12

6:30 pm-8:15 am

1 stop33h 45m

Rio de Janeiro–Galeão Intl

Thu 8/27

9:05 pm-2:49 pm

1 stop21h 44m

$762

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Francisco to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, May is the cheapest month to fly from San Francisco to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $576. If you aren’t able to travel during the month of May, then book flights to South America from San Francisco during April instead. Flights to South America in April, while not as cheap as those in May, still average around $601.

How far in advance should I book a flight from San Francisco to South America?

You are more likely to see cheaper flights to South America from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $691 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from San Francisco for as low as $665 on momondo.

Can stopping save me money on San Francisco to South America flights?

You could potentially save up to 15% on your flight if you consider stops on a San Francisco to South America flight.

Cheap San Francisco to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to South America

Fastest flight time	9h 54m
Direct flights	None

The fastest flight from San Francisco to South America takes 9h 54m

There are no direct flights from San Francisco to South America. There are no popular flight routes from San Francisco to South America.

Search flight deals

Frequently asked questions about flying from San Francisco to South America

When did momondo last update prices for flights from San Francisco Airport to South America?
Prices for flights from San Francisco Airport to South America are updated daily.
How many operators does momondo search for flights from San Francisco Airport to South America?
There are 10 operators available for flights from San Francisco Airport to South America as of July 2026.
How old do you have to be to fly from San Francisco Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.
What documentation or ID do you need to fly to South America?
The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Francisco to South America

Compare and see reviews for airlines that fly from San Francisco to South America with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $214	Free Cancellation	Rating 7.4 9,955 reviews	Search United Airlines flights
Delta	PriceFrom $223	Free Cancellation	Rating 7.8 8,453 reviews	Search Delta flights
LATAM Airlines	PriceFrom $233	Free Cancellation	Rating 7.4 1,949 reviews	Search LATAM Airlines flights
Avianca	PriceFrom $284	Free Cancellation	Rating 6.5 2,523 reviews	Search Avianca flights
JetBlue	PriceFrom $292	Free Cancellation	Rating 7.1 3,011 reviews	Search JetBlue flights
Copa Airlines	PriceFrom $302	Free Cancellation	Rating 7.6 1,566 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $448	Free Cancellation	Rating 7.1 11,788 reviews	Search American Airlines flights
Air Canada	PriceFrom $482	Free Cancellation	Rating 7.1 11,321 reviews	Search Air Canada flights
GOL	PriceFrom $499	Free Cancellation	Rating 7.3 1,257 reviews	Search GOL flights
Aeromexico	PriceFrom $652	Free Cancellation	Rating 7.4 1,480 reviews	Search Aeromexico flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to South America?

It is quick and easy to find San Francisco to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from San Francisco to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Francisco to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from San Francisco to South America?

momondo provides multiple filters to help you find the best flight to South America from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.