What is the cheapest airline that flies from San Francisco to South America?

Avianca, United Airlines, and American Airlines are the most popular carriers operating from San Francisco to South America

What airlines fly to South America?

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to South America from San Francisco according to our data. Copa Airlines is the first choice among our users, with 33% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 10 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from San Francisco Airport to South America?

Prices for flights from San Francisco Airport to South America are updated daily.

How many operators does momondo search for flights from San Francisco Airport to South America?

There are 10 operators available for flights from San Francisco Airport to South America as of April 2026.

How old do you have to be to fly from San Francisco Airport to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.

What documentation or ID do you need to fly to South America?

The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$138 Cheap Flights from San Francisco to South America in 2026

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Find the cheapest flights from San Francisco to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:55 pm - 1:10 pm

SFO

MDE

11h 15m

1 stop

2:10 pm - 10:35 pm

MDE

SFO

10h 25m

1 stop

$322Avianca

Thu, May 14 - Mon, May 18

11:55 pm - 1:10 pm

SFO

MDE

11h 15m

1 stop

2:10 pm - 10:35 pm

MDE

SFO

10h 25m

1 stop

$323Avianca

Sat, Apr 18 - Fri, May 1

5:00 am - 9:10 pm

SFO

MDE

14h 10m

1 stop

9:45 am - 7:05 pm

MDE

SFO

11h 20m

1 stop

$353United Airlines

Sat, May 2 - Wed, May 6

9:50 pm - 11:50 am

SFO

BOG

12h 00m

1 stop

6:30 am - 11:59 pm

BOG

SFO

19h 29m

1 stop

$365GOL

Mon, Jun 1 - Thu, Jun 4

6:54 pm - 4:54 am

SFO

BOG

32h 00m

1 stop

8:30 am - 12:15 am

BOG

SFO

17h 45m

1 stop

$372United Airlines

Sat, Jun 6 - Wed, Jun 10

8:13 pm - 11:50 am

SFO

BOG

13h 37m

2 stops

2:10 pm - 10:56 am

BOG

SFO

22h 46m

1 stop

$375American Airlines

Mon, Jun 1 - Thu, Jun 4

10:55 pm - 8:35 pm

SFO

BOG

19h 40m

2 stops

8:40 am - 9:04 pm

BOG

SFO

14h 24m

2 stops

$400LATAM Airlines

Mon, Jun 1 - Thu, Jun 4

8:00 am - 10:38 pm

SFO

BOG

12h 38m

1 stop

6:30 am - 11:48 pm

BOG

SFO

19h 18m

1 stop

$439American Airlines

Wed, Jun 10 - Wed, Jul 15

12:21 pm - 4:10 am

SFO

LIM

13h 49m

2 stops

10:00 pm - 3:25 pm

LIM

SFO

19h 25m

2 stops

$521GOL

Wed, Apr 15 - Mon, Apr 20

11:36 pm - 9:55 pm

SFO

LIM

20h 19m

1 stop

12:05 pm - 10:37 am

LIM

SFO

24h 32m

1 stop

$525LATAM Airlines

Sun, Apr 19 - Wed, Apr 22

American Airlines flights from San Francisco to South America

Our best American Airlines deals on San Francisco to South America flight tickets

American Airlines

Jun 1

SFO8:13 pmSan Francisco

13h 37m

2 stops

BOG11:50 amBogotá El Dorado

Jun 4

BOG2:10 pmBogotá El Dorado

22h 46m

1 stop

SFO10:56 amSan Francisco

$375

American Airlines

Jun 10

SFO8:00 amSan Francisco

12h 38m

1 stop

BOG10:38 pmBogotá El Dorado

Jul 15

BOG6:30 amBogotá El Dorado

19h 18m

1 stop

SFO11:48 pmSan Francisco

$439

American Airlines

Apr 15

SFO6:15 amSan Francisco

12h 00m

1 stop

MDE8:15 pmMedellín Jose Maria Cordova Intl

May 26

MDE6:00 amMedellín Jose Maria Cordova Intl

18h 58m

1 stop

SFO10:58 pmSan Francisco

$448

LATAM Airlines flights from San Francisco to South America

Our best LATAM Airlines deals on San Francisco to South America flight tickets

LATAM Airlines

Jun 1

SFO10:55 pmSan Francisco

19h 40m

2 stops

BOG8:35 pmBogotá El Dorado

Jun 4

BOG8:40 amBogotá El Dorado

14h 24m

2 stops

SFO9:04 pmSan Francisco

$400

LATAM Airlines

Apr 25

SFO5:50 pmSan Francisco

22h 00m

2 stops

BOG5:50 pmBogotá El Dorado

May 8

BOG11:00 amBogotá El Dorado

15h 46m

2 stops

SFO12:46 amSan Francisco

$511

LATAM Airlines

Apr 7

SFO11:35 pmSan Francisco

17h 40m

1 stop

BOG7:15 pmBogotá El Dorado

Apr 25

BOG9:00 amBogotá El Dorado

13h 24m

1 stop

SFO8:24 pmSan Francisco

$514

momondo Fare Finder

Use the filters below to find and compare flights from San Francisco to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Thu 5/14

11:55 pm-1:10 pm

1 stop11h 15m

Medellín Jose Maria Cordova Intl

Mon 5/18

2:10 pm-10:35 pm

1 stop10h 25m

$322

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sat 4/18

11:55 pm-1:10 pm

1 stop11h 15m

Medellín Jose Maria Cordova Intl

Fri 5/1

2:10 pm-10:35 pm

1 stop10h 25m

$323

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sat 5/2

5:00 am-9:10 pm

1 stop14h 10m

Medellín Jose Maria Cordova Intl

Wed 5/6

9:45 am-7:05 pm

1 stop11h 20m

$353

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Mon 6/1

9:50 pm-11:50 am

1 stop12h 00m

Bogotá El Dorado

Thu 6/4

6:30 am-11:59 pm

1 stop19h 29m

$365

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Sat 6/6

6:54 pm-4:54 am

1 stop32h 00m

Bogotá El Dorado

Wed 6/10

8:30 am-12:15 am

1 stop17h 45m

$372

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Mon 6/1

8:13 pm-11:50 am

2 stops13h 37m

Bogotá El Dorado

Thu 6/4

2:10 pm-10:56 am

1 stop22h 46m

$375

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Mon 6/1

10:55 pm-8:35 pm

2 stops19h 40m

Bogotá El Dorado

Thu 6/4

8:40 am-9:04 pm

2 stops14h 24m

$400

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Wed 6/10

8:00 am-10:38 pm

1 stop12h 38m

Bogotá El Dorado

Wed 7/15

6:30 am-11:48 pm

1 stop19h 18m

$439

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

Wed 4/15

12:21 pm-4:10 am

2 stops13h 49m

Lima J Chavez Intl

Mon 4/20

10:00 pm-3:25 pm

2 stops19h 25m

$521

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

Sun 4/19

11:36 pm-9:55 pm

1 stop20h 19m

Lima J Chavez Intl

Wed 4/22

12:05 pm-10:37 am

1 stop24h 32m

$525

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Francisco to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from San Francisco to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $612. If you aren’t able to travel during the month of February, then book flights to South America from San Francisco during March instead. Flights to South America in March, while not as cheap as those in February, still average around $629.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $691 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from San Francisco for as low as $661 on momondo.

Can stopping save me money on San Francisco to South America flights?

You could potentially save up to 4% on your flight if you consider stops on a San Francisco to South America flight.

Cheap San Francisco to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to South America

Fastest flight time	9h 49m
Direct flights	None

The fastest flight from San Francisco to South America takes 9h 49m

There are no direct flights from San Francisco to South America. There are no popular flight routes from San Francisco to South America.

Search flight deals

Frequently asked questions about flying from San Francisco to South America

When did momondo last update prices for flights from San Francisco Airport to South America?
Prices for flights from San Francisco Airport to South America are updated daily.
How many operators does momondo search for flights from San Francisco Airport to South America?
There are 10 operators available for flights from San Francisco Airport to South America as of April 2026.
How old do you have to be to fly from San Francisco Airport to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to South America.
What documentation or ID do you need to fly to South America?
The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from San Francisco to South America

Compare and see reviews for airlines that fly from San Francisco to South America with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $214	Free Cancellation	Rating 7.4 9,542 reviews	Search United Airlines flights
JetBlue	PriceFrom $224	Free Cancellation	Rating 7.2 2,913 reviews	Search JetBlue flights
LATAM Airlines	PriceFrom $234	Free Cancellation	Rating 7.4 1,908 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $269	Free Cancellation	Rating 7.5 1,578 reviews	Search Copa Airlines flights
Delta	PriceFrom $282	Free Cancellation	Rating 7.9 8,375 reviews	Search Delta flights
Avianca	PriceFrom $311	Free Cancellation	Rating 6.5 2,505 reviews	Search Avianca flights
GOL	PriceFrom $415	Free Cancellation	Rating 7.3 1,195 reviews	Search GOL flights
Aeromexico	PriceFrom $453	Free Cancellation	Rating 7.4 1,550 reviews	Search Aeromexico flights
American Airlines	PriceFrom $459	Free Cancellation	Rating 7.1 11,553 reviews	Search American Airlines flights
Air Canada	PriceFrom $565	Free Cancellation	Rating 7.1 10,889 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to South America?

It is quick and easy to find San Francisco to South America flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South America that suits you.

Can I find flights from San Francisco to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Francisco to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from San Francisco to South America?

momondo provides multiple filters to help you find the best flight to South America from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Francisco to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.