Cheap flights from San Francisco to Louisville from $109

If you are unable to visit Louisville during the month of September, then departing from San Francisco during the month August is also very affordable. Most momondo users find prices during this month for around $363.

On average, the least expensive day to fly to Louisville from San Francisco is on a Saturday. momondo users have found tickets for Saturday departures for as low as $136. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from San Francisco to Louisville on a Monday will generally be more expensive and average around $383. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

Our data shows that the cheapest San Francisco to Louisville flights are usually those with departure times in the morning. Our users have found flights to Louisville in the morning for as low as $301. At noon is when there is more demand to fly to Louisville, so prices are often more expensive at around $430 per ticket.

Fly from San Francisco to Louisville Intl for the best San Francisco - Louisville Intl flight prices

You are more likely to see cheaper flights to Louisville from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Louisville for around $481 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Louisville from San Francisco for as low as $283 on momondo.

There are 2 cabin classes available to choose from on San Francisco to Louisville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 18% on your flight if you consider stops on a San Francisco to Louisville flight.

As of August 2026, prices for San Francisco to Louisville flights are approximately 48% more expensive when compared to flights at the same time last year.

Breeze Airways and American Airlines are the most popular carriers operating from San Francisco to Louisville Intl

Delta, American Airlines and Breeze Airways are the top three most popular airlines that fly to Louisville from San Francisco according to our data. Delta is the first choice among our users, with 29% of people opting to fly with this airline when traveling to Louisville. Keep in mind that there are 7 different airlines that fly to Louisville on a routine basis, so you have a few additional options to choose from.

Chicago (MDW) was the most common stop: 40% of momondo users choosing 1-stop flights on this route connected there.

Flights via Nashville (BNA) offer the lowest average round-trip price of $394.

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 7h 32m.

Dallas (DFW) has the shortest average layover time for this route: 1h 26m.