Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from San Francisco to Des Moines from $130

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
12:00 pm - 7:30 pmSFO  San Francisco-DSM Des Moines
5h 30m1 stop Denver Intl
Frontier Logo
8:30 pm - 12:20 amDSM  Des Moines-SFO San Francisco
5h 50m1 stop Denver Intl
$238Frontier
Mon, Oct 26 - Mon, Nov 2
Frontier Logo
6:00 am - 7:30 pmSFO  San Francisco-DSM Des Moines
11h 30m1 stop Denver Intl
Frontier Logo
8:25 pm - 11:05 amDSM  Des Moines-SFO San Francisco
16h 40m1 stop Denver Intl
$239Frontier
Mon, Oct 12 - Mon, Oct 19
Multiple Airlines Logo
7:14 pm - 10:50 pmSFO  San Francisco-DSM Des Moines
25h 36m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
9:11 pm - 6:19 pmDSM  Des Moines-SFO San Francisco
23h 08m1 stop Las Vegas Harry Reid Intl
$251Multiple Airlines
Wed, Oct 28 - Mon, Nov 2
Multiple Airlines Logo
1:35 pm - 10:01 pmSFO  San Francisco-DSM Des Moines
6h 26m1 stop Santa Ana J. Wayne/Orange Cnty
Multiple Airlines Logo
9:11 pm - 8:19 amDSM  Des Moines-SFO San Francisco
13h 08m1 stop Las Vegas Harry Reid Intl
$259Multiple Airlines
Thu, Oct 22 - Mon, Oct 26
United Airlines Logo
12:45 pm - 8:21 pmSFO  San Francisco-DSM Des Moines
5h 36m1 stop Denver Intl
United Airlines Logo
8:00 am - 3:04 pmDSM  Des Moines-SFO San Francisco
9h 04m1 stop Houston George Bush Intcntl
$332United Airlines
Wed, Dec 9 - Thu, Dec 10
American Airlines Logo
11:36 pm - 8:56 amSFO  San Francisco-DSM Des Moines
7h 20m1 stop Chicago O'Hare Intl
American Airlines Logo
2:01 pm - 8:11 pmDSM  Des Moines-SFO San Francisco
8h 10m1 stop Chicago O'Hare Intl
$337American Airlines
Sat, Oct 17 - Sat, Oct 24
American Airlines Logo
1:29 pm - 12:04 amSFO  San Francisco-DSM Des Moines
8h 35m1 stop Chicago O'Hare Intl
American Airlines Logo
10:30 am - 6:09 pmDSM  Des Moines-SFO San Francisco
9h 39m1 stop Chicago O'Hare Intl
$337American Airlines
Wed, Sep 23 - Tue, Sep 29
United Airlines Logo
12:35 am - 10:30 amSFO  San Francisco-DSM Des Moines
7h 55m1 stop Chicago O'Hare Intl
United Airlines Logo
1:27 pm - 5:23 pmDSM  Des Moines-SFO San Francisco
5h 56m1 stop Denver Intl
$337United Airlines
Wed, Sep 23 - Sat, Sep 26
Southwest Logo
10:15 am - 5:50 pmSFO  San Francisco-DSM Des Moines
5h 35m1 stop Las Vegas Harry Reid Intl
Southwest Logo
6:00 am - 12:50 pmDSM  Des Moines-SFO San Francisco
8h 50m1 stop Chicago Midway
$337Southwest
Wed, Dec 9 - Thu, Dec 10
Southwest Logo
7:40 am - 5:15 pmSFO  San Francisco-DSM Des Moines
7h 35m2 stops San Diego Las Vegas Harry Reid Intl
Southwest Logo
5:55 pm - 9:15 pmDSM  Des Moines-SFO San Francisco
5h 20m1 stop Denver Intl
$342Southwest
Sat, Oct 17 - Sat, Oct 24

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Frontier flights from San Francisco to Des Moines

Our best Frontier deals on San Francisco to Des Moines flight tickets
Frontier
Oct 26
SFO12:00 pmSan Francisco
5h 30m
1 stop
DSM7:30 pmDes Moines
Nov 2
DSM8:30 pmDes Moines
5h 50m
1 stop
SFO12:20 amSan Francisco
$238
Frontier
Oct 12
SFO6:00 amSan Francisco
11h 30m
1 stop
DSM7:30 pmDes Moines
Oct 19
DSM8:25 pmDes Moines
16h 40m
1 stop
SFO11:05 amSan Francisco
$239
Frontier
Oct 23
SFO12:00 pmSan Francisco
5h 30m
1 stop
DSM7:30 pmDes Moines
Oct 26
DSM8:25 pmDes Moines
5h 50m
1 stop
SFO12:15 amSan Francisco
$254

Delta flights from San Francisco to Des Moines

Our best Delta deals on San Francisco to Des Moines flight tickets
Delta
Sep 23
SFO12:05 amSan Francisco
8h 12m
1 stop
DSM10:17 amDes Moines
Sep 26
DSM10:57 amDes Moines
8h 22m
1 stop
SFO5:19 pmSan Francisco
$337
Delta
Sep 25
SFO10:59 pmSan Francisco
8h 39m
1 stop
DSM9:38 amDes Moines
Sep 26
DSM4:10 pmDes Moines
9h 47m
1 stop
SFO11:57 pmSan Francisco
$353

momondo Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Mon 10/26

12:00 pm-7:30 pm

1 stop5h 30m

Des Moines

Mon 11/2

8:30 pm-12:20 am

1 stop5h 50m

$238

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Mon 10/12

6:00 am-7:30 pm

1 stop11h 30m

Des Moines

Mon 10/19

8:25 pm-11:05 am

1 stop16h 40m

$239

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Wed 10/28

7:14 pm-10:50 pm

1 stop25h 36m

Des Moines

Mon 11/2

9:11 pm-6:19 pm

1 stop23h 08m

$251

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Thu 10/22

1:35 pm-10:01 pm

1 stop6h 26m

Des Moines

Mon 10/26

9:11 pm-8:19 am

1 stop13h 08m

$259

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Wed 12/9

12:45 pm-8:21 pm

1 stop5h 36m

Des Moines

Thu 12/10

8:00 am-3:04 pm

1 stop9h 04m

$332

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Sat 10/17

11:36 pm-8:56 am

1 stop7h 20m

Des Moines

Sat 10/24

2:01 pm-8:11 pm

1 stop8h 10m

$337

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Wed 9/23

1:29 pm-12:04 am

1 stop8h 35m

Des Moines

Tue 9/29

10:30 am-6:09 pm

1 stop9h 39m

$337

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Wed 9/23

12:35 am-10:30 am

1 stop7h 55m

Des Moines

Sat 9/26

1:27 pm-5:23 pm

1 stop5h 56m

$337

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Wed 12/9

10:15 am-5:50 pm

1 stop5h 35m

Des Moines

Thu 12/10

6:00 am-12:50 pm

1 stop8h 50m

$337

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Sat 10/17

7:40 am-5:15 pm

2 stops7h 35m

Des Moines

Sat 10/24

5:55 pm-9:15 pm

1 stop5h 20m

$342

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from San Francisco to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Des Moines?

Prices are currently low for flights on this route.

Typical prices usually range from $323 to $526.
The lowest price recently found on this route was $238.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in February, then September is your next best option. Flight prices from San Francisco to Des Moines during September average around $420.

How have San Francisco to Des Moines flight prices changed over time?

As of September 2026, prices for San Francisco to Des Moines flights are approximately 14% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Des Moines (SFO to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Des Moines

Best Price Found

$130

Fastest flight time

5h 10m

Direct flights

None
The best one-way flight to Des Moines from San Francisco in the past 72 hours is $130. The best round-trip flight deal from San Francisco to Des Moines found on momondo in the last 72 hours is $238.
The fastest flight from San Francisco to Des Moines takes 5h 10m
There are no direct flights from San Francisco to Des Moines. There are no popular flight routes from San Francisco to Des Moines.
Search flight deals

Frequently asked questions about flying from San Francisco to Des Moines

  • How far is San Francisco to Des Moines by plane?

    The distance between San Francisco and Des Moines is about 1543.9 mi. A reasonable flight in good conditions will take 5h 10m.

  • When did momondo last update prices for flights from San Francisco Airport to Des Moines Airport?

    Prices for flights from San Francisco Airport to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Des Moines Airport?

  • How old do you have to be to fly from San Francisco Airport to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Des Moines?

Best airlines flying from San Francisco to Des Moines

Compare and see reviews for airlines that fly from San Francisco to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $201Free CancellationRating
5.6
2,615 reviews
Search Frontier flights
United AirlinesPriceFrom $324Free CancellationRating
7.4
10,173 reviews
Search United Airlines flights
American AirlinesPriceFrom $341Free CancellationRating
7.1
12,042 reviews
Search American Airlines flights
SouthwestPriceFrom $358Free CancellationRating
8.0
4,197 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Osceola
Urbandale
Newton
Johnston
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Francisco to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Francisco to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Des Moines?

Once all potential San Francisco to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Francisco to Des Moines right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of San Francisco to Des Moines flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 10/7
Wed 10/14
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States