Cheap flights from San Francisco to Des Moines from $94
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Des Moines departing on 12/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Wed 11/4
3:05 pm-7:34 pm
1 stop26h 29m
Des Moines
Wed 11/11
2:45 pm-8:19 am
1 stop19h 34m
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Mon 11/2
6:02 am-7:35 pm
1 stop11h 33m
Des Moines
Mon 11/9
8:04 pm-6:19 pm
1 stop24h 15m
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Fri 10/30
12:20 pm-7:35 pm
1 stop5h 15m
Des Moines
Fri 11/6
8:30 pm-11:17 am
1 stop16h 47m
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Mon 10/26
12:00 pm-7:30 pm
1 stop5h 30m
Des Moines
Mon 11/2
8:30 pm-12:20 am
1 stop5h 50m
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Tue 11/10
12:55 am-10:32 am
1 stop7h 37m
Des Moines
Wed 11/11
5:09 pm-11:09 pm
1 stop8h 00m
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Tue 10/27
2:18 pm-12:14 am
1 stop7h 56m
Des Moines
Thu 10/29
2:30 pm-7:39 pm
1 stop7h 09m
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Tue 11/3
12:05 pm-8:18 pm
1 stop6h 13m
Des Moines
Tue 11/10
1:58 pm-7:59 pm
1 stop8h 01m
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Sat 12/12
6:20 am-1:40 pm
1 stop5h 20m
Des Moines
Tue 12/15
6:30 pm-10:10 pm
1 stop5h 40m
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Tue 10/27
11:00 am-8:40 pm
1 stop7h 40m
Des Moines
Thu 10/29
2:00 pm-9:05 pm
2 stops9h 05m
San FranciscoDes Moines
SFO San Francisco - DSM Des Moines
SFODSM
San Francisco
Tue 10/27
10:45 am-8:36 pm
1 stop7h 51m
Des Moines
Thu 10/29
6:45 pm-11:56 pm
1 stop7h 11m
See travel insights to Des Moines from
How to get the cheapest flight ticket from San Francisco to Des Moines
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the typical price of a round-trip flight between San Francisco and Des Moines?
Prices are currently low for flights on this route.
Typical prices usually range from $368 to $692.The lowest price recently found on this route was $211.
What is the cheapest month to fly to Des Moines?
If you’re not able to fly to Des Moines in February, then December is your next best option. Flight prices from San Francisco to Des Moines during December average around $406.
How have San Francisco to Des Moines flight prices changed over time?
As of October 2026, prices for San Francisco to Des Moines flights are approximately 4% more expensive when compared to flights at the same time last year.
What is the cheapest airline that flies from San Francisco to Des Moines?
Delta and Southwest are the most popular carriers operating from San Francisco to Des Moines
What airlines fly to Des Moines?
American Airlines, Southwest and United Airlines are the top three most popular airlines that fly to Des Moines from San Francisco according to our data. American Airlines is the first choice among our users, with 34% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.
Which airport is the most popular layover for flights between San Francisco and Des Moines?
Denver (DEN) was the most common stop: 89% of momondo users choosing 1-stop flights on this route connected there.
Which layover airport offers the lowest fares from San Francisco to Des Moines?
Flights via Denver (DEN) offer the lowest average round-trip price of $355.
Which layover airport has the shortest travel time from San Francisco to Des Moines?
Flights connecting via Phoenix (PHX) have the shortest average one-way travel time: 5h 41m.
Which layover airport has the shortest connection time from San Francisco to Des Moines?
Phoenix (PHX) has the shortest average layover time for this route: 0h 47m.
When to book flights from San Francisco to Des Moines
Cheap San Francisco to Des Moines (SFO to DSM) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from San Francisco to Des Moines
Frequently asked questions about flying from San Francisco to Des Moines
How far is San Francisco to Des Moines by plane?
The distance between San Francisco and Des Moines is about 1543.9 mi. A reasonable flight in good conditions will take 5h 30m.
When did momondo last update prices for flights from San Francisco Airport to Des Moines Airport?
Prices for flights from San Francisco Airport to Des Moines Airport refresh daily.
How many operators does momondo search for flights from San Francisco Airport to Des Moines Airport?
As of October 2026, there are 4 operators available to choose from for flights from San Francisco Airport to Des Moines Airport.
How old do you have to be to fly from San Francisco Airport to Des Moines Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from San Francisco to Des Moines?
Based on momondo bookings for this flight route, the most popular airline on flight routes from San Francisco to Des Moines is American Airlines (39% of total bookings). The next most popular airlines are United Airlines (31%), Frontier (15%), and Southwest (15%).
Best airlines flying from San Francisco to Des Moines
Compare and see reviews for airlines that fly from San Francisco to Des Moines with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $230 | Free Cancellation | Rating 5.6 2,551 reviews | |||
| PriceFrom $324 | Free Cancellation | Rating 7.4 10,329 reviews | |||
| PriceFrom $326 | Free Cancellation | Rating 7.0 12,148 reviews | |||
| PriceFrom $358 | Free Cancellation | Rating 7.9 4,225 reviews |
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from San Francisco to Des Moines?
momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Francisco to Des Moines. Millions of users trust and use momondo every year so you are in good hands.
Can I find flights from San Francisco to Des Moines with flexible booking policies on momondo?
Yes. All flights to Des Moines from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.
How can momondo help me find flights from San Francisco to Des Moines?
Once all potential San Francisco to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.
I’m not ready to book a flight from San Francisco to Des Moines right now. Can momondo alert me if prices change?
Of course. momondo tracks the price of San Francisco to Des Moines flights. All you need is a valid email address and we will do the rest; it is that quick and easy.