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Cheap flights from San Francisco to Des Moines from $98

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:35 am - 10:26 pmSFO  San Francisco-DSM Des Moines
9h 51m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
3:40 pm - 5:43 pmDSM  Des Moines-SFO San Francisco
28h 03m2 stops Phoenix-Mesa Gateway Las Vegas Harry Reid Intl
$230Multiple Airlines
Thu, Dec 3 - Tue, Dec 8
Multiple Airlines Logo
9:06 pm - 8:28 pmSFO  San Francisco-DSM Des Moines
21h 22m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
9:18 pm - 1:27 pmDSM  Des Moines-SFO San Francisco
18h 09m1 stop Las Vegas Harry Reid Intl
$230Multiple Airlines
Thu, Dec 3 - Mon, Dec 7
Frontier Logo
6:30 am - 7:42 pmSFO  San Francisco-DSM Des Moines
11h 12m1 stop Denver Intl
Frontier Logo
8:26 pm - 12:35 amDSM  Des Moines-SFO San Francisco
6h 09m1 stop Denver Intl
$245Frontier
Thu, Dec 10 - Thu, Dec 17
Frontier Logo
6:15 am - 7:31 pmSFO  San Francisco-DSM Des Moines
11h 16m1 stop Denver Intl
Frontier Logo
8:17 pm - 12:35 amDSM  Des Moines-SFO San Francisco
6h 18m1 stop Denver Intl
$270Frontier
Thu, Dec 17 - Thu, Jan 7
American Airlines Logo
7:03 am - 7:10 pmSFO  San Francisco-DSM Des Moines
10h 07m1 stop Los Angeles
American Airlines Logo
2:05 pm - 10:11 pmDSM  Des Moines-SFO San Francisco
10h 06m1 stop Chicago O'Hare Intl
$356American Airlines
Mon, Dec 7 - Thu, Dec 10
American Airlines Logo
10:52 pm - 9:12 amSFO  San Francisco-DSM Des Moines
8h 20m1 stop Chicago O'Hare Intl
American Airlines Logo
9:16 pm - 9:09 amDSM  Des Moines-SFO San Francisco
13h 53m1 stop Los Angeles
$361American Airlines
Tue, Dec 29 - Tue, Jan 5
United Airlines Logo
12:10 am - 10:37 amSFO  San Francisco-DSM Des Moines
8h 27m1 stop Chicago O'Hare Intl
United Airlines Logo
5:15 pm - 9:23 pmDSM  Des Moines-SFO San Francisco
6h 08m1 stop Denver Intl
$364United Airlines
Wed, Dec 2 - Thu, Dec 3
Southwest Logo
2:20 pm - 9:40 pmSFO  San Francisco-DSM Des Moines
5h 20m1 stop Denver Intl
Southwest Logo
7:10 pm - 10:55 pmDSM  Des Moines-SFO San Francisco
5h 45m1 stop Denver Intl
$369Southwest
Mon, Feb 8 - Fri, Feb 12
Southwest Logo
10:10 am - 5:50 pmSFO  San Francisco-DSM Des Moines
5h 40m1 stop Las Vegas Harry Reid Intl
Southwest Logo
7:00 am - 3:45 pmDSM  Des Moines-SFO San Francisco
10h 45m2 stops Denver Intl San Diego
$374Southwest
Wed, Dec 2 - Sat, Dec 5
United Airlines Logo
6:15 am - 4:13 pmSFO  San Francisco-DSM Des Moines
7h 58m1 stop Denver Intl
United Airlines Logo
8:00 am - 3:04 pmDSM  Des Moines-SFO San Francisco
9h 04m1 stop Houston George Bush Intcntl
$489United Airlines
Mon, Dec 7 - Thu, Dec 10

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American Airlines flights from San Francisco to Des Moines

Our best American Airlines deals on San Francisco to Des Moines flight tickets
American Airlines
Nov 21
SFO11:25 pmSan Francisco
7h 42m
1 stop
DSM9:07 amDes Moines
Dec 1
DSM7:16 pmDes Moines
7h 31m
1 stop
SFO12:47 amSan Francisco
$557
American Airlines
Nov 19
SFO1:54 pmSan Francisco
8h 25m
1 stop
DSM12:19 amDes Moines
Dec 1
DSM7:16 pmDes Moines
7h 31m
1 stop
SFO12:47 amSan Francisco
$564
American Airlines
Nov 21
SFO8:29 amSan Francisco
6h 48m
1 stop
DSM5:17 pmDes Moines
Nov 28
DSM5:00 amDes Moines
7h 09m
1 stop
SFO10:09 amSan Francisco
$697

United Airlines flights from San Francisco to Des Moines

Our best United Airlines deals on San Francisco to Des Moines flight tickets
United Airlines
Nov 21
SFO10:45 pmSan Francisco
9h 47m
1 stop
DSM10:32 amDes Moines
Dec 1
DSM5:15 pmDes Moines
16h 06m
2 stops
SFO7:21 amSan Francisco
$716
United Airlines
Nov 19
SFO12:27 pmSan Francisco
7h 28m
1 stop
DSM9:55 pmDes Moines
Dec 1
DSM8:00 amDes Moines
13h 47m
2 stops
SFO7:47 pmSan Francisco
$802
United Airlines
Nov 16
SFO2:24 pmSan Francisco
7h 18m
1 stop
DSM11:42 pmDes Moines
Nov 19
DSM5:30 amDes Moines
5h 59m
1 stop
SFO9:29 amSan Francisco
$816

momondo Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Thu 12/3

10:35 am-10:26 pm

1 stop9h 51m

Des Moines

Tue 12/8

3:40 pm-5:43 pm

2 stops28h 03m

$230

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Thu 12/3

9:06 pm-8:28 pm

1 stop21h 22m

Des Moines

Mon 12/7

9:18 pm-1:27 pm

1 stop18h 09m

$230

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Thu 12/10

6:30 am-7:42 pm

1 stop11h 12m

Des Moines

Thu 12/17

8:26 pm-12:35 am

1 stop6h 09m

$245

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Thu 12/17

6:15 am-7:31 pm

1 stop11h 16m

Des Moines

Thu 1/7

8:17 pm-12:35 am

1 stop6h 18m

$270

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Mon 12/7

7:03 am-7:10 pm

1 stop10h 07m

Des Moines

Thu 12/10

2:05 pm-10:11 pm

1 stop10h 06m

$356

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Tue 12/29

10:52 pm-9:12 am

1 stop8h 20m

Des Moines

Tue 1/5

9:16 pm-9:09 am

1 stop13h 53m

$361

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Wed 12/2

12:10 am-10:37 am

1 stop8h 27m

Des Moines

Thu 12/3

5:15 pm-9:23 pm

1 stop6h 08m

$364
Quickest round-trip

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Mon 2/8

2:20 pm-9:40 pm

1 stop5h 20m

Des Moines

Fri 2/12

7:10 pm-10:55 pm

1 stop5h 45m

$369

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Wed 12/2

10:10 am-5:50 pm

1 stop5h 40m

Des Moines

Sat 12/5

7:00 am-3:45 pm

2 stops10h 45m

$374

San FranciscoDes Moines

SFO San Francisco - DSM Des Moines

SFODSM

San Francisco

Mon 12/7

6:15 am-4:13 pm

1 stop7h 58m

Des Moines

Thu 12/10

8:00 am-3:04 pm

1 stop9h 04m

$489

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from San Francisco to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Des Moines?

Prices are currently low for flights on this route.

Typical prices usually range from $467 to $822.
The lowest price recently found on this route was $215.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in February, then June is your next best option. Flight prices from San Francisco to Des Moines during June average around $466.

How have San Francisco to Des Moines flight prices changed over time?

As of November 2026, prices for San Francisco to Des Moines flights are approximately 15% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Des Moines (SFO to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Des Moines

Best Price Found

$98

Fastest flight time

5h 34m

Direct flights

None
The best one-way flight to Des Moines from San Francisco in the past 72 hours is $98. The best round-trip flight deal from San Francisco to Des Moines found on momondo in the last 72 hours is $230.
The fastest flight from San Francisco to Des Moines takes 5h 34m
There are no direct flights from San Francisco to Des Moines. There are no popular flight routes from San Francisco to Des Moines.
Search flight deals

Frequently asked questions about flying from San Francisco to Des Moines

  • How far is San Francisco to Des Moines by plane?

    The distance between San Francisco and Des Moines is about 1543.9 mi. A reasonable flight in good conditions will take 5h 34m.

  • When did momondo last update prices for flights from San Francisco Airport to Des Moines Airport?

    Prices for flights from San Francisco Airport to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Des Moines Airport?

  • How old do you have to be to fly from San Francisco Airport to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Des Moines?

Best airlines flying from San Francisco to Des Moines

Compare and see reviews for airlines that fly from San Francisco to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $230Free CancellationRating
5.5
2,510 reviews
Search Frontier flights
American AirlinesPriceFrom $326Free CancellationRating
7.0
12,227 reviews
Search American Airlines flights
SouthwestPriceFrom $358Free CancellationRating
8.0
4,216 reviews
Search Southwest flights
United AirlinesPriceFrom $406Free CancellationRating
7.3
10,472 reviews
Search United Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Osceola
Urbandale
Johnston
Boone
Newton
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Francisco to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Francisco to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Des Moines?

Once all potential San Francisco to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Francisco to Des Moines right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of San Francisco to Des Moines flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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