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Cheap flights from San Diego to St. Louis from $60

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to St. Louis departing on 2/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Diego to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
4:47 pm - 10:02 amSAN-STL
15h 15m1 stop
Frontier Logo
3:43 pm - 11:07 pmSTL-SAN
9h 24m1 stop
$116Frontier
Find Deal
Fri, Jan 9 - Wed, Jan 14
Frontier Logo
12:00 pm - 2:48 pmSAN-STL
24h 48m1 stop
Frontier Logo
3:43 pm - 11:07 pmSTL-SAN
9h 24m1 stop
$122Frontier
Find Deal
Tue, Jan 13 - Sat, Jan 17
Frontier Logo
4:47 pm - 10:02 amSAN-STL
15h 15m1 stop
Frontier Logo
3:43 pm - 11:07 pmSTL-SAN
9h 24m1 stop
$127Frontier
Find Deal
Fri, Jan 9 - Sat, Jan 17
Frontier Logo
4:47 pm - 10:02 amSAN-STL
15h 15m1 stop
Frontier Logo
7:43 pm - 5:09 pmSTL-SAN
23h 26m1 stop
$130Frontier
Find Deal
Fri, Jan 9 - Mon, Jan 12
Frontier Logo
12:00 pm - 2:48 pmSAN-STL
24h 48m1 stop
Frontier Logo
7:27 pm - 12:15 amSTL-SAN
6h 48m1 stop
$135Frontier
Find Deal
Tue, Jan 13 - Fri, Jan 16
Frontier Logo
4:47 pm - 10:02 amSAN-STL
15h 15m1 stop
Frontier Logo
7:27 pm - 12:15 amSTL-SAN
6h 48m1 stop
$140Frontier
Find Deal
Fri, Jan 9 - Fri, Jan 16
Frontier Logo
11:47 am - 10:02 amSAN-STL
20h 15m1 stop
Frontier Logo
3:43 pm - 11:07 pmSTL-SAN
9h 24m1 stop
$141Frontier
Find Deal
Sun, Jan 11 - Sat, Jan 17
Frontier Logo
7:00 am - 10:02 amSAN-STL
25h 02m1 stop
Frontier Logo
9:03 pm - 2:12 pmSTL-SAN
19h 09m1 stop
$146Frontier
Find Deal
Tue, Jan 6 - Fri, Jan 16
Frontier Logo
6:30 am - 6:44 pmSAN-STL
10h 14m1 stop
Frontier Logo
9:32 pm - 8:51 amSTL-SAN
13h 19m1 stop
$148Frontier
Find Deal
Fri, Jan 30 - Sun, Feb 1
Frontier Logo
2:56 pm - 8:48 pmSAN-STL
27h 52m1 stop
Frontier Logo
9:32 pm - 8:51 amSTL-SAN
13h 19m1 stop
$149Frontier
Find Deal
Thu, Jan 29 - Sun, Feb 1

Frontier flights from San Diego to St. Louis

Our best Frontier deals on San Diego to St. Louis flight tickets
Frontier
Jan 9
SAN4:47 pmSan Diego
15h 15m
1 stop
STL10:02 amLambert-St Louis
Jan 14
STL3:43 pmLambert-St Louis
9h 24m
1 stop
SAN11:07 pmSan Diego
$116
Find similar
Frontier
Jan 13
SAN12:00 pmSan Diego
24h 48m
1 stop
STL2:48 pmLambert-St Louis
Jan 17
STL3:43 pmLambert-St Louis
9h 24m
1 stop
SAN11:07 pmSan Diego
$122
Find similar
Frontier
Jan 9
SAN4:47 pmSan Diego
15h 15m
1 stop
STL10:02 amLambert-St Louis
Jan 17
STL3:43 pmLambert-St Louis
9h 24m
1 stop
SAN11:07 pmSan Diego
$127
Find similar

Delta flights from San Diego to St. Louis

Our best Delta deals on San Diego to St. Louis flight tickets
Delta
Dec 17
SAN7:05 pmSan Diego
12h 05m
2 stops
STL9:10 amLambert-St Louis
Jan 7
STL7:00 amLambert-St Louis
11h 40m
2 stops
SAN4:40 pmSan Diego
$511
Find similar
Delta
Dec 17
SAN12:24 pmSan Diego
7h 33m
1 stop
STL9:57 pmLambert-St Louis
Dec 24
STL7:00 amLambert-St Louis
10h 21m
1 stop
SAN3:21 pmSan Diego
$514
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 3, 2025.
Use the filters below to find and compare flights from San Diego to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Fri 1/9

4:47 pm-10:02 am

1 stop15h 15m

Lambert-St Louis

Wed 1/14

3:43 pm-11:07 pm

1 stop9h 24m

$116

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Tue 1/13

12:00 pm-2:48 pm

1 stop24h 48m

Lambert-St Louis

Sat 1/17

3:43 pm-11:07 pm

1 stop9h 24m

$122

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Fri 1/9

4:47 pm-10:02 am

1 stop15h 15m

Lambert-St Louis

Sat 1/17

3:43 pm-11:07 pm

1 stop9h 24m

$127

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Fri 1/9

4:47 pm-10:02 am

1 stop15h 15m

Lambert-St Louis

Mon 1/12

7:43 pm-5:09 pm

1 stop23h 26m

$130

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Tue 1/13

12:00 pm-2:48 pm

1 stop24h 48m

Lambert-St Louis

Fri 1/16

7:27 pm-12:15 am

1 stop6h 48m

$135

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Fri 1/9

4:47 pm-10:02 am

1 stop15h 15m

Lambert-St Louis

Fri 1/16

7:27 pm-12:15 am

1 stop6h 48m

$140

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Sun 1/11

11:47 am-10:02 am

1 stop20h 15m

Lambert-St Louis

Sat 1/17

3:43 pm-11:07 pm

1 stop9h 24m

$141

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Tue 1/6

7:00 am-10:02 am

1 stop25h 02m

Lambert-St Louis

Fri 1/16

9:03 pm-2:12 pm

1 stop19h 09m

$146

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Fri 1/30

6:30 am-6:44 pm

1 stop10h 14m

Lambert-St Louis

Sun 2/1

9:32 pm-8:51 am

1 stop13h 19m

$148

San DiegoSt. Louis

SAN - STL

SANSTL

San Diego

Thu 1/29

2:56 pm-8:48 pm

1 stop27h 52m

Lambert-St Louis

Sun 2/1

9:32 pm-8:51 am

1 stop13h 19m

$149

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from San Diego to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from San Diego to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $271. The month of February is another great option to travel to St. Louis, with average flight prices from San Diego averaging around $307.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $429. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $556. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from San Diego in the evening is the least expensive time of day to depart. momondo users have found prices as low as $198 when looking at flights departing in the evening. In the afternoon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $492 per ticket.

What is the cheapest San Diego to Lambert-St Louis flight route?

Fly from San Diego to Lambert-St Louis for the best San Diego - Lambert-St Louis flight prices

How far in advance should I book a flight to St. Louis?

You are more likely to see cheaper flights to St. Louis from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $382 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from San Diego for as low as $306 on momondo.

What cabin class options are available on San Diego to Lambert-St Louis flights?

There is only 1 cabin class available to choose from on San Diego to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to St. Louis flights?

No. A direct flight is the cheapest option for a flight between San Diego to St. Louis.

How have San Diego to St. Louis flight prices changed over time?

As of December 2025, prices for San Diego to St. Louis flights are approximately 106% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to St. Louis (SAN to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to St. Louis

Best Price Found

$226

Fastest flight time

3h 30m

Direct flights

Every day

Airports in St. Louis

1 airport
The best one-way flight to St. Louis from San Diego in the past 72 hours is $226. The best round-trip flight deal from San Diego to St. Louis found on momondo in the last 72 hours is $419.
The fastest flight from San Diego to St. Louis takes 3h 30m
Direct flights go from San Diego to St. Louis every day.
There is 1 airport near St. Louis: Lambert-St Louis (STL)
Search flight deals

  • How far is San Diego to Lambert-St Louis by plane?

    Lambert-St Louis is 1560.0 mi away from San Diego. 5h 46m is a normal flight duration for this route.

  • When did momondo last update prices for flights from San Diego Airport to Lambert-St Louis Airport?

    Prices for flights from San Diego Airport to Lambert-St Louis Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from San Diego Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Diego Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents you'll need for your trip to Lambert-St Louis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Lambert-St Louis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from San Diego to St. Louis?

  • What is the most popular airline from San Diego to St. Louis?

Best airlines flying from San Diego to St. Louis

Compare and see reviews for airlines that fly from San Diego to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $117Free CancellationRating
5.8
3,094 reviews
Search Frontier flights
DeltaPriceFrom $184Free CancellationRating
7.9
8,011 reviews
Search Delta flights
American AirlinesPriceFrom $249Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights
United AirlinesPriceFrom $256Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights
SouthwestPriceFrom $306Free CancellationRating
8.0
4,253 reviews
Search Southwest flights

  • Southwest Flights From San Diego to St. Louis

    Southwest is one of the most popular airlines flying from San Diego to St. Louis, operating 6 flights/week on average for this route. A good Southwest flight deal for San Diego to St. Louis starts from $306 round-trip, up to an average price of $479. Our users have rated Southwest at 8.0/10.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
O'Fallon
Florissant
Fenton
Wentzville
Collinsville
St. Peters
Alton
Farmington
Clayton
Festus
Glencoe
Edwardsville
Eureka
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to St. Louis?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from San Diego to St. Louis. momondo saves you time and could save you money on your trip.

Can I find flights from San Diego to St. Louis with flexible booking policies on momondo?

Flights from San Diego to St. Louis with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Diego to St. Louis?

Once all potential San Diego to St. Louis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to St. Louis right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Diego to St. Louis now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to St. Louis and let you know when they change.

An easier way to manage your St. Louis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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