What is the most punctual flight time for San Diego to Knoxville flights?

Generally, flights departing in the morning tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

How often are flights from San Diego to Knoxville delayed?

Historically, on average around 0% of flights between San Diego and Knoxville have experienced a delay on any given week. The average delay length over the past 12 months has been 0 minutes.

What is the cheapest airline that flies from San Diego to Knoxville McGhee Tyson?

United Airlines, Delta, and Southwest are the most popular carriers operating from San Diego to Knoxville McGhee Tyson

Which layover airport offers the lowest fares from San Diego to Knoxville?

Flights via Denver (DEN) offer the lowest average round-trip price of $593.

What day of the week experiences the fewest flight delays on this route?

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Saturday has historically seen more delays on average compared to the rest of the week.

What airlines fly to Knoxville?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from San Diego according to our data. American Airlines is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 6 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from San Diego to Knoxville?

Flights connecting via Denver (DEN) have the shortest average one-way travel time: 6h 17m.

Which airport is the most popular layover for flights between San Diego and Knoxville?

Dallas (DFW) was the most common stop: 33% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest connection time from San Diego to Knoxville?

Atlanta (ATL) has the shortest average layover time for this route: 1h 08m.

When did momondo last update prices for flights from San Diego Airport to Knoxville McGhee Tyson Airport?

Prices for flights from San Diego Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

How many operators does momondo search for flights from San Diego Airport to Knoxville McGhee Tyson Airport?

As of August 2026, there are 6 operators available to choose from for flights from San Diego Airport to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from San Diego Airport to Knoxville McGhee Tyson Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Diego Airport to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$108 Cheap Flights from San Diego to Knoxville in 2026

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Find the cheapest flights from San Diego to Knoxville

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:32 pm - 1:11 pm-

13h 39m

6:30 am - 3:41 pm-

12h 11m

$248Multiple Airlines

Wed, Oct 28 - Sun, Nov 1

6:25 am - 10:52 pm-

13h 27m

8:00 am - 9:05 am-

28h 05m

$258Multiple Airlines

Thu, Aug 27 - Mon, Aug 31

11:00 am - 11:18 pm-

9h 18m

8:10 am - 12:48 pm-

7h 38m

$363American Airlines

Sat, Aug 29 - Wed, Sep 2

10:20 pm - 9:43 am-

8h 23m

6:03 am - 11:57 am-

8h 54m

$363American Airlines

Wed, Aug 26 - Sat, Aug 29

11:48 am - 11:00 pm-

8h 12m

6:20 am - 10:44 am-

7h 24m

$363Delta

Sat, Sep 5 - Sat, Sep 12

10:56 am - 8:15 pm-

6h 19m

4:40 pm - 9:19 pm-

7h 39m

$363Delta

Wed, Sep 9 - Wed, Sep 16

12:33 pm - 10:29 pm-

6h 56m

1:59 pm - 6:30 pm-

7h 31m

$363United Airlines

Tue, Aug 25 - Sat, Aug 29

11:30 am - 9:00 pm-

6h 30m

7:25 pm - 12:30 am-

8h 05m

$363Southwest

Tue, Oct 20 - Mon, Oct 26

6:20 am - 5:40 pm-

8h 20m

3:00 pm - 8:30 pm-

8h 30m

$368Southwest

Sat, Aug 29 - Wed, Sep 2

10:16 am - 9:57 pm-

8h 41m

4:25 pm - 10:28 pm-

9h 03m

$404United Airlines

Thu, Nov 26 - Tue, Dec 1

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Southwest flights from San Diego to Knoxville

Our best Southwest deals on San Diego to Knoxville flight tickets

Southwest

Aug 27

SAN7:50 amSan Diego

7h 45m

2 stops

TYS6:35 pmKnoxville McGhee Tyson

Sep 3

TYS2:05 pmKnoxville McGhee Tyson

8h 50m

2 stops

SAN7:55 pmSan Diego

$373

Southwest

Aug 19

SAN7:05 amSan Diego

8h 50m

2 stops

TYS6:55 pmKnoxville McGhee Tyson

Sep 28

TYS4:50 pmKnoxville McGhee Tyson

8h 15m

1 stop

SAN10:05 pmSan Diego

$397

Southwest

Aug 16

SAN8:55 pmSan Diego

13h 30m

2 stops

TYS1:25 pmKnoxville McGhee Tyson

Aug 19

TYS3:00 pmKnoxville McGhee Tyson

9h 05m

2 stops

SAN9:05 pmSan Diego

$491

Frontier flights from San Diego to Knoxville

Our best Frontier deals on San Diego to Knoxville flight tickets

Frontier

Aug 12

SAN6:25 amSan Diego

9h 59m

1 stop

TYS7:24 pmKnoxville McGhee Tyson

Aug 17

TYS8:19 pmKnoxville McGhee Tyson

6h 32m

1 stop

SAN11:51 pmSan Diego

$345

Frontier

Aug 12

SAN6:25 amSan Diego

9h 59m

1 stop

TYS7:24 pmKnoxville McGhee Tyson

Aug 17

TYS8:19 pmKnoxville McGhee Tyson

6h 32m

1 stop

SAN11:51 pmSan Diego

$372

Frontier

Aug 7

SAN10:10 amSan Diego

6h 14m

1 stop

TYS7:24 pmKnoxville McGhee Tyson

Aug 10

TYS8:19 pmKnoxville McGhee Tyson

6h 32m

1 stop

SAN11:51 pmSan Diego

$402

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Wed 10/28

8:32 pm-1:11 pm

1 stop13h 39m

Knoxville McGhee Tyson

Sun 11/1

6:30 am-3:41 pm

1 stop12h 11m

$248

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Thu 8/27

6:25 am-10:52 pm

1 stop13h 27m

Knoxville McGhee Tyson

Mon 8/31

8:00 am-9:05 am

2 stops28h 05m

$258

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Sat 8/29

11:00 am-11:18 pm

1 stop9h 18m

Knoxville McGhee Tyson

Wed 9/2

8:10 am-12:48 pm

1 stop7h 38m

$363

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Wed 8/26

10:20 pm-9:43 am

1 stop8h 23m

Knoxville McGhee Tyson

Sat 8/29

6:03 am-11:57 am

1 stop8h 54m

$363

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Sat 9/5

11:48 am-11:00 pm

1 stop8h 12m

Knoxville McGhee Tyson

Sat 9/12

6:20 am-10:44 am

1 stop7h 24m

$363

Quickest round-trip

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Wed 9/9

10:56 am-8:15 pm

1 stop6h 19m

Knoxville McGhee Tyson

Wed 9/16

4:40 pm-9:19 pm

1 stop7h 39m

$363

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Tue 8/25

12:33 pm-10:29 pm

1 stop6h 56m

Knoxville McGhee Tyson

Sat 8/29

1:59 pm-6:30 pm

1 stop7h 31m

$363

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Tue 10/20

11:30 am-9:00 pm

1 stop6h 30m

Knoxville McGhee Tyson

Mon 10/26

7:25 pm-12:30 am

1 stop8h 05m

$363

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Sat 8/29

6:20 am-5:40 pm

2 stops8h 20m

Knoxville McGhee Tyson

Wed 9/2

3:00 pm-8:30 pm

1 stop8h 30m

$368

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Thu 11/26

10:16 am-9:57 pm

1 stop8h 41m

Knoxville McGhee Tyson

Tue 12/1

4:25 pm-10:28 pm

1 stop9h 03m

$404

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Diego to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

Layovers

What is the typical price of a round-trip flight between San Diego and Knoxville?

Prices are currently low for flights on this route.

Typical prices usually range from $399 to $543.
The lowest price recently found on this route was $248.

What is the cheapest month to fly to Knoxville?

The month of May is, on average, the cheapest month to fly to Knoxville from San Diego, with most prices found around $414. If you aren’t able to travel during the month of May, then book flights to Knoxville from San Diego during December instead. Flights to Knoxville in December, while not as cheap as those in May, still average around $417.

What is the cheapest San Diego to Knoxville McGhee Tyson flight route?

Fly from San Diego to Knoxville McGhee Tyson for the best San Diego - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight from San Diego to Knoxville?

You are more likely to see cheaper flights to Knoxville from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $473 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from San Diego for as low as $398 on momondo.

What cabin class options are available on San Diego to Knoxville flights?

There is only 1 cabin class available to choose from on San Diego to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have San Diego to Knoxville flight prices changed over time?

As of August 2026, prices for San Diego to Knoxville flights are approximately 36% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap San Diego to Knoxville (SAN to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Knoxville

Fastest flight time	5h 55m
Direct flights	None

The fastest flight from San Diego to Knoxville takes 5h 55m

There are no direct flights from San Diego to Knoxville. There are no popular flight routes from San Diego to Knoxville.

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Frequently asked questions about flying from San Diego to Knoxville

How far is San Diego to Knoxville McGhee Tyson by plane?
There are 1898.9 mi between San Diego and Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 5h 55m.
When did momondo last update prices for flights from San Diego Airport to Knoxville McGhee Tyson Airport?
Prices for flights from San Diego Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.
How many operators does momondo search for flights from San Diego Airport to Knoxville McGhee Tyson Airport?
As of August 2026, there are 6 operators available to choose from for flights from San Diego Airport to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from San Diego Airport to Knoxville McGhee Tyson Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Diego Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from San Diego to Knoxville?
Based on momondo bookings for this flight route, the most popular airline on flight routes from San Diego to Knoxville is American Airlines (47% of total bookings). The next most popular airlines are Delta (20%), United Airlines (16%), and Frontier (9%).

Best airlines flying from San Diego to Knoxville

Compare and see reviews for airlines that fly from San Diego to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $65	Free Cancellation	Rating 5.6 2,738 reviews	Search Frontier flights
Delta	PriceFrom $276	Free Cancellation	Rating 7.8 8,483 reviews	Search Delta flights
United Airlines	PriceFrom $277	Free Cancellation	Rating 7.4 10,060 reviews	Search United Airlines flights
American Airlines	PriceFrom $277	Free Cancellation	Rating 7.1 11,851 reviews	Search American Airlines flights
Southwest	PriceFrom $336	Free Cancellation	Rating 8.0 4,222 reviews	Search Southwest flights
Alaska Airlines	PriceFrom $496	Free Cancellation	Rating 7.9 12,762 reviews	Search Alaska Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Alcoa

Maryville

Crossville

Murphy

Oak Ridge

Kodak

Newport

Lenoir City

Dandridge

Clinton

Jefferson City

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Diego to Knoxville for you.

Can I find flights from San Diego to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Diego to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from San Diego. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Diego to Knoxville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Knoxville from San Diego. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Cheap flights from San Diego to Knoxville from $108

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Knoxville departing on 9/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Southwest flights from San Diego to Knoxville

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How to get the cheapest flight ticket from San Diego to Knoxville

What is the typical price of a round-trip flight between San Diego and Knoxville?

What is the cheapest month to fly to Knoxville?

What is the cheapest San Diego to Knoxville McGhee Tyson flight route?

How far in advance should I book a flight from San Diego to Knoxville?

What cabin class options are available on San Diego to Knoxville flights?

How have San Diego to Knoxville flight prices changed over time?

What is the cheapest airline that flies from San Diego to Knoxville McGhee Tyson?

What airlines fly to Knoxville?

How often are flights from San Diego to Knoxville delayed?

What is the most punctual flight time for San Diego to Knoxville flights?

What day of the week experiences the fewest flight delays on this route?

Which airport is the most popular layover for flights between San Diego and Knoxville?

Which layover airport offers the lowest fares from San Diego to Knoxville?

Which layover airport has the shortest travel time from San Diego to Knoxville?

Which layover airport has the shortest connection time from San Diego to Knoxville?

When to book flights from San Diego to Knoxville

Cheap San Diego to Knoxville (SAN to TYS) flight deals and tips

Fastest flight time

Direct flights

Frequently asked questions about flying from San Diego to Knoxville

Best airlines flying from San Diego to Knoxville

Compare and see reviews for airlines that fly from San Diego to Knoxville with momondo

Traveling to a place near Knoxville?

Why use momondo?

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

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List of cabin classes available on flights landing in Knoxville. Availability may vary depending on flight origin and airline.

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