Cheap flights from San Diego to Knoxville from $126
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Knoxville departing on 6/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
Discover deals from 900+ travel sites with momondo.
Save money when you book flights with momondo
Big names and deals
Big names and deals
Search 100s of travel sites to compare prices.Filter for what you want
Filter for what you want
Free Wi-Fi? Stopover? Instantly customize your results.Trusted and free
Trusted and free
We’re completely free to use - no hidden charges or fees.Price Alerts
Price Alerts
Not ready to book? to track prices.Find the cheapest flights from San Diego to Knoxville
Cheap round-trip flights
Cheap one-way flights
Cheap last minute flights
Alaska Airlines flights from San Diego to Knoxville
Our best Alaska Airlines deals on San Diego to Knoxville flight tickets
Frontier flights from San Diego to Knoxville
Our best Frontier deals on San Diego to Knoxville flight tickets
See travel insights to Knoxville from
How to get the cheapest flight ticket from San Diego to Knoxville
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Knoxville?
The month of January is, on average, the cheapest month to fly to Knoxville from San Diego, with most prices found around $318. If you aren’t able to travel during the month of January, then book flights to Knoxville from San Diego during July instead. Flights to Knoxville in July, while not as cheap as those in January, still average around $381.
What is the cheapest day to depart on your flight to Knoxville?
The cheapest day to depart from San Diego to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $391. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to Knoxville for around $660.
What is the cheapest time of day to depart on your flight to Knoxville?
At noon is the cheapest time of day to fly from San Diego to Knoxville when you can find flight prices for as low as $413. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $528.
How far in advance should I book a flight to Knoxville?
You are more likely to see cheaper flights to Knoxville from San Diego when booking 21 weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $426 when searching 21 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from San Diego for as low as $338 on momondo.
What is the cheapest airline that flies from San Diego to Knoxville McGhee Tyson?
Delta, United Airlines, and American Airlines are the most popular carriers operating from San Diego to Knoxville McGhee Tyson
What airlines fly to Knoxville?
American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Knoxville from San Diego according to our data. American Airlines is the first choice among our users, with 69% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 5 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.
When to book flights from San Diego to Knoxville
Cheap San Diego to Knoxville (SAN to TYS) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from San Diego to Knoxville
How far is San Diego to Knoxville McGhee Tyson by plane?
There are 1898.9 mi between San Diego and Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 6h 05m.
When did momondo last update prices for flights from San Diego Airport to Knoxville McGhee Tyson Airport?
Prices for flights from San Diego Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.
How many operators does momondo search for flights from San Diego Airport to Knoxville McGhee Tyson Airport?
As of June 2025, there are 5 operators available to choose from for flights from San Diego Airport to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from San Diego Airport to Knoxville McGhee Tyson Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from San Diego Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from San Diego to Knoxville?
Based on momondo bookings for this flight route, the most popular airline on flight routes from San Diego to Knoxville is American Airlines (66% of total bookings). The next most popular airlines are Delta (16%), United Airlines (13%), and Frontier (3%).
Best airlines flying from San Diego to Knoxville
Compare and see reviews for airlines that fly from San Diego to Knoxville with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $84 | Free Cancellation | Rating 5.9 3,295 reviews | |||
| PriceFrom $228 | Free Cancellation | Rating 7.4 8,790 reviews | |||
| PriceFrom $273 | Free Cancellation | Rating 7.2 10,000 reviews | |||
| PriceFrom $276 | Free Cancellation | Rating 8.0 7,946 reviews | |||
| PriceFrom $378 | Free Cancellation | Rating 8.0 10,000 reviews |
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from San Diego to Knoxville?
We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Diego to Knoxville for you.
Can I find flights from San Diego to Knoxville with flexible booking policies on momondo?
Yes. All flights to Knoxville from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.
How can momondo help me find flights from San Diego to Knoxville?
momondo provides multiple filters to help you find the best flight to Knoxville from San Diego. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.
I’m not ready to book a flight from San Diego to Knoxville right now. Can momondo alert me if prices change?
Yes momondo offers price alerts on flights to Knoxville from San Diego. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.