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Cheap flights from San Diego to Des Moines from $138

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Des Moines departing on 2/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from San Diego to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:35 am - 7:04 pm
SAN
-
DSM
8h 29m1 stop
Frontier Logo
7:27 pm - 12:08 am
DSM
-
SAN
6h 41m1 stop
$138Frontier
Fri, Feb 27 - Sun, Mar 1
Frontier Logo
11:59 am - 7:04 pm
SAN
-
DSM
29h 05m1 stop
Frontier Logo
7:27 pm - 12:08 am
DSM
-
SAN
6h 41m1 stop
$141Frontier
Thu, Feb 26 - Sun, Mar 1
Frontier Logo
6:36 pm - 7:04 pm
SAN
-
DSM
22h 28m2 stops
Frontier Logo
7:27 pm - 10:45 am
DSM
-
SAN
17h 18m1 stop
$177Frontier
Thu, Feb 26 - Sun, Mar 1
Frontier Logo
6:25 am - 6:47 pm
SAN
-
DSM
10h 22m1 stop
Frontier Logo
7:32 pm - 12:08 am
DSM
-
SAN
6h 36m1 stop
$210Frontier
Thu, Feb 12 - Thu, Feb 19
Frontier Logo
6:25 am - 6:47 pm
SAN
-
DSM
10h 22m1 stop
Frontier Logo
7:32 pm - 7:40 am
DSM
-
SAN
14h 08m1 stop
$213Frontier
Thu, Feb 12 - Thu, Feb 19
Multiple Airlines Logo
12:00 pm - 10:09 pm
SAN
-
DSM
32h 09m2 stops
Multiple Airlines Logo
4:30 pm - 7:31 pm
DSM
-
SAN
29h 01m1 stop
$227Multiple Airlines
Wed, Jan 14 - Sun, Jan 18
Multiple Airlines Logo
2:56 pm - 10:19 am
SAN
-
DSM
17h 23m2 stops
Multiple Airlines Logo
8:30 am - 8:51 am
DSM
-
SAN
26h 21m1 stop
$236Multiple Airlines
Thu, Jan 22 - Sun, Jan 25
Frontier Logo
6:36 pm - 6:19 pm
SAN
-
DSM
21h 43m2 stops
Frontier Logo
7:32 pm - 12:08 am
DSM
-
SAN
6h 36m1 stop
$250Frontier
Thu, Feb 12 - Thu, Feb 19
Multiple Airlines Logo
2:56 pm - 3:40 pm
SAN
-
DSM
22h 44m1 stop
Multiple Airlines Logo
4:30 pm - 1:57 pm
DSM
-
SAN
23h 27m1 stop
$260Multiple Airlines
Thu, Jan 22 - Sun, Jan 25
Multiple Airlines Logo
9:45 pm - 4:50 pm
SAN
-
DSM
17h 05m1 stop
Multiple Airlines Logo
8:30 am - 8:50 pm
DSM
-
SAN
14h 20m2 stops
$273Multiple Airlines
Fri, Feb 6 - Sun, Feb 8

United Airlines flights from San Diego to Des Moines

Our best United Airlines deals on San Diego to Des Moines flight tickets
United Airlines
Jan 31
SAN12:11 pmSan Diego
8h 19m
1 stop
DSM10:30 pmDes Moines
Feb 10
DSM5:09 pmDes Moines
5h 33m
1 stop
SAN8:42 pmSan Diego
$297
Find similar
United Airlines
Jan 31
SAN11:08 amSan Diego
9h 22m
2 stops
DSM10:30 pmDes Moines
Feb 10
DSM5:09 pmDes Moines
5h 33m
1 stop
SAN8:42 pmSan Diego
$302
Find similar
United Airlines
Feb 14
SAN11:30 amSan Diego
6h 37m
1 stop
DSM8:07 pmDes Moines
Feb 18
DSM3:24 pmDes Moines
9h 20m
1 stop
SAN10:44 pmSan Diego
$335
Find similar

Delta flights from San Diego to Des Moines

Our best Delta deals on San Diego to Des Moines flight tickets
Delta
Jun 25
SAN10:30 pmSan Diego
8h 49m
1 stop
DSM9:19 amDes Moines
Jun 30
DSM2:35 pmDes Moines
7h 46m
1 stop
SAN8:21 pmSan Diego
$415
Find similar
Delta
May 22
SAN10:30 pmSan Diego
8h 49m
1 stop
DSM9:19 amDes Moines
May 25
DSM2:35 pmDes Moines
7h 46m
1 stop
SAN8:21 pmSan Diego
$445
Find similar
Delta
Jun 25
SAN10:30 pmSan Diego
8h 49m
1 stop
DSM9:19 amDes Moines
Jun 30
DSM2:35 pmDes Moines
7h 46m
1 stop
SAN8:21 pmSan Diego
$461
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from San Diego to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Fri 2/27

8:35 am-7:04 pm

1 stop8h 29m

Des Moines

Sun 3/1

7:27 pm-12:08 am

1 stop6h 41m

$138

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 2/26

11:59 am-7:04 pm

1 stop29h 05m

Des Moines

Sun 3/1

7:27 pm-12:08 am

1 stop6h 41m

$141

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 2/26

6:36 pm-7:04 pm

2 stops22h 28m

Des Moines

Sun 3/1

7:27 pm-10:45 am

1 stop17h 18m

$177

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 2/12

6:25 am-6:47 pm

1 stop10h 22m

Des Moines

Thu 2/19

7:32 pm-12:08 am

1 stop6h 36m

$210

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 2/12

6:25 am-6:47 pm

1 stop10h 22m

Des Moines

Thu 2/19

7:32 pm-7:40 am

1 stop14h 08m

$213

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Wed 1/14

12:00 pm-10:09 pm

2 stops32h 09m

Des Moines

Sun 1/18

4:30 pm-7:31 pm

1 stop29h 01m

$227

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 1/22

2:56 pm-10:19 am

2 stops17h 23m

Des Moines

Sun 1/25

8:30 am-8:51 am

1 stop26h 21m

$236

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 2/12

6:36 pm-6:19 pm

2 stops21h 43m

Des Moines

Thu 2/19

7:32 pm-12:08 am

1 stop6h 36m

$250

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 1/22

2:56 pm-3:40 pm

1 stop22h 44m

Des Moines

Sun 1/25

4:30 pm-1:57 pm

1 stop23h 27m

$260

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Fri 2/6

9:45 pm-4:50 pm

1 stop17h 05m

Des Moines

Sun 2/8

8:30 am-8:50 pm

2 stops14h 20m

$273

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from San Diego to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in November, then July is your next best option. Flight prices from San Diego to Des Moines during July average around $329.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from San Diego to Des Moines is on a Sunday. Travelers who choose to depart for Des Moines on a Sunday will often find tickets for as low as $140. Flights from San Diego to Des Moines on a Monday will generally be more expensive and average around $171. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest San Diego to Des Moines flight route?

Fly from San Diego to Des Moines for the best San Diego - Des Moines flight prices

What cabin class options are available on San Diego to Des Moines flights?

There is only 1 cabin class available to choose from on San Diego to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Des Moines flights?

No. A direct flight is the cheapest option for a flight between San Diego to Des Moines.

How have San Diego to Des Moines flight prices changed over time?

As of December 2025, prices for San Diego to Des Moines flights are approximately 14% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Des Moines (SAN to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Des Moines

Fastest flight time

8h 49m

Direct flights

None
The fastest flight from San Diego to Des Moines takes 8h 49m
There are no direct flights from San Diego to Des Moines. There are no popular flight routes from San Diego to Des Moines.
Search flight deals

  • How far is San Diego to Des Moines by plane?

    San Diego and Des Moines are 1426.2 mi apart from one another. Typically, this will take 8h 49m by plane in normal conditions.

  • When did momondo last update prices for flights from San Diego Airport to Des Moines Airport?

    Prices for flights from San Diego Airport to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Des Moines Airport?

  • How old do you have to be to fly from San Diego Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from San Diego to Des Moines?

  • What is the most popular airline from San Diego to Des Moines?

Best airlines flying from San Diego to Des Moines

Compare and see reviews for airlines that fly from San Diego to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $75Free CancellationRating
7.2
701 reviews
Search Allegiant Air flights
DeltaPriceFrom $148Free CancellationRating
7.9
8,013 reviews
Search Delta flights
FrontierPriceFrom $162Free CancellationRating
5.7
3,069 reviews
Search Frontier flights
SouthwestPriceFrom $286Free CancellationRating
8.0
4,251 reviews
Search Southwest flights
United AirlinesPriceFrom $286Free CancellationRating
7.4
9,124 reviews
Search United Airlines flights
American AirlinesPriceFrom $286Free CancellationRating
7.2
11,075 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Diego to Des Moines?

momondo helps you find the best flight between San Diego and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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