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Cheap flights from San Diego to Des Moines from $96

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Des Moines departing on 8/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Diego to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:51 pm - 8:31 pm
SAN
-
DSM
21h 40m
1 stop
Multiple Airlines Logo
10:06 pm - 2:08 pm
DSM
-
SAN
18h 02m
1 stop
$237Multiple Airlines
Thu, Aug 6 - Mon, Aug 10
Multiple Airlines Logo
8:51 pm - 8:31 pm
SAN
-
DSM
21h 40m
1 stop
Multiple Airlines Logo
10:06 pm - 2:08 pm
DSM
-
SAN
18h 02m
1 stop
$243Multiple Airlines
Thu, Aug 6 - Mon, Aug 10
Multiple Airlines Logo
9:43 pm - 7:48 pm
SAN
-
DSM
20h 05m
1 stop
Multiple Airlines Logo
9:56 pm - 8:48 pm
DSM
-
SAN
24h 52m
1 stop
$249Multiple Airlines
Thu, Sep 17 - Sun, Sep 20
Multiple Airlines Logo
8:51 pm - 8:31 pm
SAN
-
DSM
21h 40m
1 stop
Multiple Airlines Logo
10:06 pm - 3:43 pm
DSM
-
SAN
19h 37m
2 stops
$257Multiple Airlines
Thu, Aug 6 - Mon, Aug 10
Frontier Logo
6:25 am - 1:34 pm
SAN
-
DSM
5h 09m
1 stop
Frontier Logo
2:19 pm - 9:10 am
DSM
-
SAN
20h 51m
1 stop
$259Frontier
Wed, Jul 22 - Wed, Aug 5
Multiple Airlines Logo
8:51 pm - 8:31 pm
SAN
-
DSM
21h 40m
1 stop
Multiple Airlines Logo
10:06 pm - 3:43 pm
DSM
-
SAN
19h 37m
2 stops
$262Multiple Airlines
Thu, Aug 6 - Mon, Aug 10
Frontier Logo
10:10 am - 1:34 pm
SAN
-
DSM
25h 24m
1 stop
Frontier Logo
2:19 pm - 11:51 pm
DSM
-
SAN
11h 32m
1 stop
$269Frontier
Thu, Aug 13 - Mon, Aug 17
Multiple Airlines Logo
8:51 pm - 9:16 pm
SAN
-
DSM
22h 25m
1 stop
Multiple Airlines Logo
10:06 pm - 8:15 pm
DSM
-
SAN
24h 09m
2 stops
$277Multiple Airlines
Thu, Aug 13 - Mon, Aug 17
Multiple Airlines Logo
4:12 pm - 3:02 pm
SAN
-
DSM
20h 50m
1 stop
Multiple Airlines Logo
9:33 pm - 8:06 pm
DSM
-
SAN
24h 33m
1 stop
$280Multiple Airlines
Thu, Jul 30 - Sun, Aug 2
Multiple Airlines Logo
3:03 pm - 8:43 pm
SAN
-
DSM
27h 40m
1 stop
Multiple Airlines Logo
10:01 pm - 2:08 pm
DSM
-
SAN
18h 07m
1 stop
$285Multiple Airlines
Wed, Jul 29 - Mon, Aug 3

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American Airlines flights from San Diego to Des Moines

Our best American Airlines deals on San Diego to Des Moines flight tickets
American Airlines
Aug 11
SAN10:45 pmSan Diego
9h 11m
1 stop
DSM9:56 amDes Moines
Aug 18
DSM6:55 amDes Moines
7h 26m
1 stop
SAN12:21 pmSan Diego
$341
American Airlines
Aug 11
SAN10:45 pmSan Diego
9h 11m
1 stop
DSM9:56 amDes Moines
Aug 18
DSM6:55 amDes Moines
7h 26m
1 stop
SAN12:21 pmSan Diego
$347
American Airlines
Aug 18
SAN2:23 pmSan Diego
7h 02m
1 stop
DSM11:25 pmDes Moines
Aug 20
DSM5:30 amDes Moines
5h 20m
1 stop
SAN8:50 amSan Diego
$361

Frontier flights from San Diego to Des Moines

Our best Frontier deals on San Diego to Des Moines flight tickets
Frontier
Jul 22
SAN6:25 amSan Diego
5h 09m
1 stop
DSM1:34 pmDes Moines
Aug 5
DSM2:19 pmDes Moines
20h 51m
1 stop
SAN9:10 amSan Diego
$259
Frontier
Aug 13
SAN10:10 amSan Diego
25h 24m
1 stop
DSM1:34 pmDes Moines
Aug 17
DSM2:19 pmDes Moines
11h 32m
1 stop
SAN11:51 pmSan Diego
$269
Frontier
Jul 29
SAN6:25 amSan Diego
5h 09m
1 stop
DSM1:34 pmDes Moines
Aug 5
DSM2:19 pmDes Moines
20h 51m
1 stop
SAN9:10 amSan Diego
$288

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 3, 2026.
Use the filters below to find and compare flights from San Diego to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 8/6

8:51 pm-8:31 pm

1 stop21h 40m

Des Moines

Mon 8/10

10:06 pm-2:08 pm

1 stop18h 02m

$237

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 8/6

8:51 pm-8:31 pm

1 stop21h 40m

Des Moines

Mon 8/10

10:06 pm-2:08 pm

1 stop18h 02m

$243

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 9/17

9:43 pm-7:48 pm

1 stop20h 05m

Des Moines

Sun 9/20

9:56 pm-8:48 pm

1 stop24h 52m

$249

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 8/6

8:51 pm-8:31 pm

1 stop21h 40m

Des Moines

Mon 8/10

10:06 pm-3:43 pm

2 stops19h 37m

$257
Quickest round-trip

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Wed 7/22

6:25 am-1:34 pm

1 stop5h 09m

Des Moines

Wed 8/5

2:19 pm-9:10 am

1 stop20h 51m

$259

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 8/6

8:51 pm-8:31 pm

1 stop21h 40m

Des Moines

Mon 8/10

10:06 pm-3:43 pm

2 stops19h 37m

$262

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 8/13

10:10 am-1:34 pm

1 stop25h 24m

Des Moines

Mon 8/17

2:19 pm-11:51 pm

1 stop11h 32m

$269

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 8/13

8:51 pm-9:16 pm

1 stop22h 25m

Des Moines

Mon 8/17

10:06 pm-8:15 pm

2 stops24h 09m

$277

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 7/30

4:12 pm-3:02 pm

1 stop20h 50m

Des Moines

Sun 8/2

9:33 pm-8:06 pm

1 stop24h 33m

$280

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Wed 7/29

3:03 pm-8:43 pm

1 stop27h 40m

Des Moines

Mon 8/3

10:01 pm-2:08 pm

1 stop18h 07m

$285

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from San Diego to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in November, then October is your next best option. Flight prices from San Diego to Des Moines during October average around $358.

What is the cheapest San Diego to Des Moines flight route?

Fly from San Diego to Des Moines for the best San Diego - Des Moines flight prices

What cabin class options are available on San Diego to Des Moines flights?

There is only 1 cabin class available to choose from on San Diego to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Des Moines flights?

No. A direct flight is the cheapest option for a flight between San Diego to Des Moines.

How have San Diego to Des Moines flight prices changed over time?

As of July 2026, prices for San Diego to Des Moines flights are approximately 17% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Des Moines (SAN to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Des Moines

Fastest flight time

7h 39m

Direct flights

None
The fastest flight from San Diego to Des Moines takes 7h 39m
There are no direct flights from San Diego to Des Moines. There are no popular flight routes from San Diego to Des Moines.
Search flight deals

Frequently asked questions about flying from San Diego to Des Moines

  • How far is San Diego to Des Moines by plane?

    San Diego and Des Moines are 1426.2 mi apart from one another. Typically, this will take 7h 39m by plane in normal conditions.

  • When did momondo last update prices for flights from San Diego Airport to Des Moines Airport?

    Prices for flights from San Diego Airport to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Des Moines Airport?

  • How old do you have to be to fly from San Diego Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from San Diego to Des Moines?

  • What is the most popular airline from San Diego to Des Moines?

Best airlines flying from San Diego to Des Moines

Compare and see reviews for airlines that fly from San Diego to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $148Free CancellationRating
7.8
8,453 reviews
Search Delta flights
FrontierPriceFrom $158Free CancellationRating
5.6
2,847 reviews
Search Frontier flights
SouthwestPriceFrom $247Free CancellationRating
7.9
4,250 reviews
Search Southwest flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
9,927 reviews
Search United Airlines flights
American AirlinesPriceFrom $296Free CancellationRating
7.1
11,764 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Osceola
Urbandale
Newton
Johnston
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Diego to Des Moines?

momondo helps you find the best flight between San Diego and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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