Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from San Diego to Des Moines from $122

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Des Moines departing on 1/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from San Diego to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
4:10 pm - 11:44 pm
SAN
-
DSM
5h 34m1 stop
United Airlines Logo
3:04 pm - 9:56 pm
DSM
-
SAN
8h 52m1 stop
$276United Airlines
Tue, Jan 13 - Tue, Jan 20
United Airlines Logo
11:08 am - 11:44 pm
SAN
-
DSM
10h 36m2 stops
United Airlines Logo
1:35 pm - 5:28 pm
DSM
-
SAN
5h 53m1 stop
$281United Airlines
Tue, Jan 13 - Tue, Jan 20
Southwest Logo
7:10 am - 2:40 pm
SAN
-
DSM
5h 30m1 stop
Southwest Logo
2:20 pm - 8:20 pm
DSM
-
SAN
8h 00m1 stop
$316Southwest
Wed, Feb 4 - Mon, Feb 9
Southwest Logo
9:40 am - 7:20 pm
SAN
-
DSM
7h 40m2 stops
Southwest Logo
2:20 pm - 8:20 pm
DSM
-
SAN
8h 00m1 stop
$321Southwest
Wed, Feb 4 - Mon, Feb 9
Frontier Logo
4:47 pm - 7:44 pm
SAN
-
DSM
24h 57m1 stop
Frontier Logo
8:29 pm - 2:34 pm
DSM
-
SAN
20h 05m1 stop
$326Frontier
Thu, Jan 1 - Mon, Jan 5
Frontier Logo
6:25 am - 7:44 pm
SAN
-
DSM
11h 19m1 stop
Frontier Logo
8:29 pm - 11:59 pm
DSM
-
SAN
5h 30m1 stop
$332Frontier
Sat, Dec 27 - Sat, Jan 3
United Airlines Logo
1:51 pm - 10:30 pm
SAN
-
DSM
6h 39m1 stop
United Airlines Logo
5:30 am - 9:20 am
DSM
-
SAN
5h 50m1 stop
$334United Airlines
Thu, Feb 5 - Tue, Feb 10
United Airlines Logo
1:00 pm - 8:34 pm
SAN
-
DSM
5h 34m1 stop
United Airlines Logo
3:35 pm - 10:33 pm
DSM
-
SAN
8h 58m1 stop
$335United Airlines
Fri, Feb 6 - Mon, Feb 9
United Airlines Logo
1:51 pm - 10:30 pm
SAN
-
DSM
6h 39m1 stop
United Airlines Logo
5:30 am - 12:49 pm
DSM
-
SAN
9h 19m2 stops
$339United Airlines
Thu, Feb 5 - Tue, Feb 10
United Airlines Logo
1:00 pm - 8:34 pm
SAN
-
DSM
5h 34m1 stop
United Airlines Logo
5:09 pm - 11:42 pm
DSM
-
SAN
8h 33m2 stops
$340United Airlines
Fri, Feb 6 - Mon, Feb 9

Frontier flights from San Diego to Des Moines

Our best Frontier deals on San Diego to Des Moines flight tickets
Frontier
Feb 19
SAN6:25 amSan Diego
10h 22m
1 stop
DSM6:47 pmDes Moines
Feb 23
DSM7:17 pmDes Moines
6h 51m
1 stop
SAN12:08 amSan Diego
$182
Find similar
Frontier
Jan 1
SAN4:47 pmSan Diego
24h 57m
1 stop
DSM7:44 pmDes Moines
Jan 5
DSM8:29 pmDes Moines
20h 05m
1 stop
SAN2:34 pmSan Diego
$326
Find similar
Frontier
Dec 27
SAN6:25 amSan Diego
11h 19m
1 stop
DSM7:44 pmDes Moines
Jan 3
DSM8:29 pmDes Moines
5h 30m
1 stop
SAN11:59 pmSan Diego
$332
Find similar

United Airlines flights from San Diego to Des Moines

Our best United Airlines deals on San Diego to Des Moines flight tickets
United Airlines
Jan 13
SAN4:10 pmSan Diego
5h 34m
1 stop
DSM11:44 pmDes Moines
Jan 20
DSM3:04 pmDes Moines
8h 52m
1 stop
SAN9:56 pmSan Diego
$276
Find similar
United Airlines
Jan 13
SAN11:08 amSan Diego
10h 36m
2 stops
DSM11:44 pmDes Moines
Jan 20
DSM1:35 pmDes Moines
5h 53m
1 stop
SAN5:28 pmSan Diego
$281
Find similar
United Airlines
Jan 16
SAN11:08 amSan Diego
9h 22m
2 stops
DSM10:30 pmDes Moines
Jan 18
DSM1:35 pmDes Moines
8h 19m
2 stops
SAN7:54 pmSan Diego
$305
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from San Diego to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Tue 1/13

4:10 pm-11:44 pm

1 stop5h 34m

Des Moines

Tue 1/20

3:04 pm-9:56 pm

1 stop8h 52m

$276

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Tue 1/13

11:08 am-11:44 pm

2 stops10h 36m

Des Moines

Tue 1/20

1:35 pm-5:28 pm

1 stop5h 53m

$281

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Wed 2/4

7:10 am-2:40 pm

1 stop5h 30m

Des Moines

Mon 2/9

2:20 pm-8:20 pm

1 stop8h 00m

$316

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Wed 2/4

9:40 am-7:20 pm

2 stops7h 40m

Des Moines

Mon 2/9

2:20 pm-8:20 pm

1 stop8h 00m

$321

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 1/1

4:47 pm-7:44 pm

1 stop24h 57m

Des Moines

Mon 1/5

8:29 pm-2:34 pm

1 stop20h 05m

$326

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Sat 12/27

6:25 am-7:44 pm

1 stop11h 19m

Des Moines

Sat 1/3

8:29 pm-11:59 pm

1 stop5h 30m

$332

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 2/5

1:51 pm-10:30 pm

1 stop6h 39m

Des Moines

Tue 2/10

5:30 am-9:20 am

1 stop5h 50m

$334

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Fri 2/6

1:00 pm-8:34 pm

1 stop5h 34m

Des Moines

Mon 2/9

3:35 pm-10:33 pm

1 stop8h 58m

$335

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 2/5

1:51 pm-10:30 pm

1 stop6h 39m

Des Moines

Tue 2/10

5:30 am-12:49 pm

2 stops9h 19m

$339

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Fri 2/6

1:00 pm-8:34 pm

1 stop5h 34m

Des Moines

Mon 2/9

5:09 pm-11:42 pm

2 stops8h 33m

$340

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from San Diego to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in November, then July is your next best option. Flight prices from San Diego to Des Moines during July average around $329.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from San Diego to Des Moines is on a Sunday. Travelers who choose to depart for Des Moines on a Sunday will often find tickets for as low as $140. Flights from San Diego to Des Moines on a Wednesday will generally be more expensive and average around $436. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from San Diego to Des Moines in the afternoon for as low as $171. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the evening because they tend to be around $562. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest San Diego to Des Moines flight route?

Fly from San Diego to Des Moines for the best San Diego - Des Moines flight prices

What cabin class options are available on San Diego to Des Moines flights?

There is only 1 cabin class available to choose from on San Diego to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Des Moines flights?

You could potentially save up to 24% on your flight if you consider stops on a San Diego to Des Moines flight.

How have San Diego to Des Moines flight prices changed over time?

As of December 2025, prices for San Diego to Des Moines flights are approximately 2% cheaper when compared to flights at the same time last year.

When to book flights from San Diego to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Des Moines (SAN to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Des Moines

Fastest flight time

5h 20m

Direct flights

None
The fastest flight from San Diego to Des Moines takes 5h 20m
There are no direct flights from San Diego to Des Moines. There are no popular flight routes from San Diego to Des Moines.
Search flight deals

  • How far is San Diego to Des Moines by plane?

    San Diego and Des Moines are 1426.2 mi apart from one another. Typically, this will take 5h 20m by plane in normal conditions.

  • When did momondo last update prices for flights from San Diego Airport to Des Moines Airport?

    Prices for flights from San Diego Airport to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Des Moines Airport?

  • How old do you have to be to fly from San Diego Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from San Diego to Des Moines?

  • What is the most popular airline from San Diego to Des Moines?

Best airlines flying from San Diego to Des Moines

Compare and see reviews for airlines that fly from San Diego to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $75Free CancellationRating
7.2
700 reviews
Search Allegiant Air flights
DeltaPriceFrom $148Free CancellationRating
7.9
8,006 reviews
Search Delta flights
FrontierPriceFrom $162Free CancellationRating
5.8
3,082 reviews
Search Frontier flights
SouthwestPriceFrom $286Free CancellationRating
7.9
4,249 reviews
Search Southwest flights
United AirlinesPriceFrom $286Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights
American AirlinesPriceFrom $286Free CancellationRating
7.2
11,053 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Diego to Des Moines?

momondo helps you find the best flight between San Diego and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 1/17
Sat 1/24
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States