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Cheap flights from San Diego to Des Moines from $83

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Des Moines departing on 6/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Diego to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
9:37 am - 1:31 pm
SAN
-
DSM
25h 54m
1 stop
Frontier Logo
2:16 pm - 8:42 am
DSM
-
SAN
20h 26m
1 stop
$185Frontier
Tue, May 26 - Fri, May 29
Frontier Logo
6:25 am - 1:31 pm
SAN
-
DSM
5h 06m
1 stop
Frontier Logo
2:16 pm - 11:50 pm
DSM
-
SAN
11h 34m
1 stop
$210Frontier
Wed, May 27 - Wed, Jun 3
Multiple Airlines Logo
6:25 am - 10:31 pm
SAN
-
DSM
38h 06m
2 stops
Multiple Airlines Logo
2:16 pm - 11:50 pm
DSM
-
SAN
11h 34m
1 stop
$241Multiple Airlines
Wed, May 27 - Wed, Jun 3
Frontier Logo
6:25 am - 1:31 pm
SAN
-
DSM
5h 06m
1 stop
Frontier Logo
2:16 pm - 9:09 am
DSM
-
SAN
20h 53m
1 stop
$250Frontier
Fri, Jun 19 - Mon, Jun 22
American Airlines Logo
7:28 am - 6:36 pm
SAN
-
DSM
9h 08m
1 stop
American Airlines Logo
1:37 pm - 9:48 pm
DSM
-
SAN
10h 11m
1 stop
$251American Airlines
Tue, Jun 2 - Tue, Jun 9
Multiple Airlines Logo
4:17 pm - 12:59 pm
SAN
-
DSM
18h 42m
2 stops
Multiple Airlines Logo
2:16 pm - 8:42 am
DSM
-
SAN
20h 26m
1 stop
$263Multiple Airlines
Tue, May 26 - Fri, May 29
American Airlines Logo
10:45 pm - 8:13 am
SAN
-
DSM
7h 28m
1 stop
American Airlines Logo
4:48 pm - 11:59 pm
DSM
-
SAN
9h 11m
1 stop
$277American Airlines
Tue, May 26 - Sat, May 30
Multiple Airlines Logo
6:25 am - 10:31 pm
SAN
-
DSM
38h 06m
2 stops
Multiple Airlines Logo
10:26 pm - 6:41 pm
DSM
-
SAN
22h 15m
1 stop
$282Multiple Airlines
Wed, May 27 - Sun, May 31
Frontier Logo
6:25 am - 1:31 pm
SAN
-
DSM
5h 06m
1 stop
Frontier Logo
2:16 pm - 11:50 pm
DSM
-
SAN
11h 34m
1 stop
$290Frontier
Mon, Jun 1 - Mon, Jun 8
Multiple Airlines Logo
10:07 pm - 8:44 pm
SAN
-
DSM
20h 37m
1 stop
Multiple Airlines Logo
10:26 pm - 6:41 pm
DSM
-
SAN
22h 15m
1 stop
$294Multiple Airlines
Wed, May 27 - Sun, May 31

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Frontier flights from San Diego to Des Moines

Our best Frontier deals on San Diego to Des Moines flight tickets
Frontier
May 26
SAN9:37 amSan Diego
25h 54m
1 stop
DSM1:31 pmDes Moines
May 29
DSM2:16 pmDes Moines
20h 26m
1 stop
SAN8:42 amSan Diego
$185
Frontier
May 27
SAN6:25 amSan Diego
5h 06m
1 stop
DSM1:31 pmDes Moines
Jun 3
DSM2:16 pmDes Moines
11h 34m
1 stop
SAN11:50 pmSan Diego
$210
Frontier
Jun 19
SAN6:25 amSan Diego
5h 06m
1 stop
DSM1:31 pmDes Moines
Jun 22
DSM2:16 pmDes Moines
20h 53m
1 stop
SAN9:09 amSan Diego
$250

United Airlines flights from San Diego to Des Moines

Our best United Airlines deals on San Diego to Des Moines flight tickets
United Airlines
Jun 2
SAN10:55 amSan Diego
7h 35m
1 stop
DSM8:30 pmDes Moines
Jun 9
DSM5:17 pmDes Moines
8h 37m
2 stops
SAN11:54 pmSan Diego
$432
United Airlines
May 16
SAN12:10 pmSan Diego
8h 35m
1 stop
DSM10:45 pmDes Moines
May 23
DSM5:17 pmDes Moines
8h 37m
2 stops
SAN11:54 pmSan Diego
$462
United Airlines
May 16
SAN10:55 amSan Diego
8h 40m
2 stops
DSM9:35 pmDes Moines
May 23
DSM5:17 pmDes Moines
8h 37m
2 stops
SAN11:54 pmSan Diego
$468

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from San Diego to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Tue 5/26

9:37 am-1:31 pm

1 stop25h 54m

Des Moines

Fri 5/29

2:16 pm-8:42 am

1 stop20h 26m

$185

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Wed 5/27

6:25 am-1:31 pm

1 stop5h 06m

Des Moines

Wed 6/3

2:16 pm-11:50 pm

1 stop11h 34m

$210

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Wed 5/27

6:25 am-10:31 pm

2 stops38h 06m

Des Moines

Wed 6/3

2:16 pm-11:50 pm

1 stop11h 34m

$241

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Fri 6/19

6:25 am-1:31 pm

1 stop5h 06m

Des Moines

Mon 6/22

2:16 pm-9:09 am

1 stop20h 53m

$250

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Tue 6/2

7:28 am-6:36 pm

1 stop9h 08m

Des Moines

Tue 6/9

1:37 pm-9:48 pm

1 stop10h 11m

$251

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Tue 5/26

4:17 pm-12:59 pm

2 stops18h 42m

Des Moines

Fri 5/29

2:16 pm-8:42 am

1 stop20h 26m

$263
Quickest round-trip

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Tue 5/26

10:45 pm-8:13 am

1 stop7h 28m

Des Moines

Sat 5/30

4:48 pm-11:59 pm

1 stop9h 11m

$277

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Wed 5/27

6:25 am-10:31 pm

2 stops38h 06m

Des Moines

Sun 5/31

10:26 pm-6:41 pm

1 stop22h 15m

$282

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Mon 6/1

6:25 am-1:31 pm

1 stop5h 06m

Des Moines

Mon 6/8

2:16 pm-11:50 pm

1 stop11h 34m

$290

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Wed 5/27

10:07 pm-8:44 pm

1 stop20h 37m

Des Moines

Sun 5/31

10:26 pm-6:41 pm

1 stop22h 15m

$294

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from San Diego to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in November, then July is your next best option. Flight prices from San Diego to Des Moines during July average around $303.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from San Diego to Des Moines is on a Sunday. Travelers who choose to depart for Des Moines on a Sunday will often find tickets for as low as $140. Flights from San Diego to Des Moines on a Monday will generally be more expensive and average around $171. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest San Diego to Des Moines flight route?

Fly from San Diego to Des Moines for the best San Diego - Des Moines flight prices

Can stopping save me money on San Diego to Des Moines flights?

No. A direct flight is the cheapest option for a flight between San Diego to Des Moines.

How have San Diego to Des Moines flight prices changed over time?

As of April 2026, prices for San Diego to Des Moines flights are approximately 114% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Des Moines (SAN to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Des Moines

Fastest flight time

5h 33m

Direct flights

None
The fastest flight from San Diego to Des Moines takes 5h 33m
There are no direct flights from San Diego to Des Moines. There are no popular flight routes from San Diego to Des Moines.
Search flight deals

Frequently asked questions about flying from San Diego to Des Moines

  • How far is San Diego to Des Moines by plane?

    San Diego and Des Moines are 1426.2 mi apart from one another. Typically, this will take 5h 33m by plane in normal conditions.

  • When did momondo last update prices for flights from San Diego Airport to Des Moines Airport?

    Prices for flights from San Diego Airport to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Des Moines Airport?

  • How old do you have to be to fly from San Diego Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from San Diego to Des Moines?

  • What is the most popular airline from San Diego to Des Moines?

Best airlines flying from San Diego to Des Moines

Compare and see reviews for airlines that fly from San Diego to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $69Free CancellationRating
7.3
706 reviews
Search Allegiant Air flights
DeltaPriceFrom $148Free CancellationRating
7.9
8,466 reviews
Search Delta flights
FrontierPriceFrom $158Free CancellationRating
5.6
2,970 reviews
Search Frontier flights
SouthwestPriceFrom $247Free CancellationRating
8.0
4,314 reviews
Search Southwest flights
United AirlinesPriceFrom $286Free CancellationRating
7.4
9,675 reviews
Search United Airlines flights
American AirlinesPriceFrom $286Free CancellationRating
7.1
11,676 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Diego to Des Moines?

momondo helps you find the best flight between San Diego and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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