Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from San Diego to Des Moines from $75

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Des Moines departing on 1/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from San Diego to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:34 am - 7:03 pmSAN-DSM
10h 29m1 stop
Frontier Logo
7:58 pm - 11:59 pmDSM-SAN
6h 01m1 stop
$127Frontier
Find Deal
Fri, Dec 5 - Mon, Dec 8
Frontier Logo
6:34 am - 7:03 pmSAN-DSM
10h 29m1 stop
Frontier Logo
7:58 pm - 5:53 pmDSM-SAN
23h 55m2 stops
$158Frontier
Find Deal
Fri, Dec 5 - Mon, Dec 8
Delta Logo
7:50 am - 5:03 pmSAN-DSM
7h 13m1 stop
Delta Logo
10:20 am - 6:21 pmDSM-SAN
10h 01m1 stop
$297Delta
Find Deal
Wed, Dec 10 - Wed, Dec 17
Delta Logo
6:20 am - 5:03 pmSAN-DSM
8h 43m1 stop
Delta Logo
11:23 am - 6:18 pmDSM-SAN
8h 55m1 stop
$301Delta
Find Deal
Thu, Dec 11 - Tue, Dec 16
United Airlines Logo
11:02 am - 8:48 pmSAN-DSM
7h 46m2 stops
United Airlines Logo
5:45 am - 9:15 amDSM-SAN
5h 30m1 stop
$302United Airlines
Find Deal
Tue, Dec 2 - Tue, Dec 9
United Airlines Logo
11:02 am - 8:48 pmSAN-DSM
7h 46m2 stops
United Airlines Logo
1:31 pm - 7:52 pmDSM-SAN
8h 21m2 stops
$307United Airlines
Find Deal
Tue, Dec 2 - Tue, Dec 9
American Airlines Logo
10:07 am - 11:59 pmSAN-DSM
11h 52m1 stop
American Airlines Logo
3:38 pm - 8:16 pmDSM-SAN
6h 38m1 stop
$316American Airlines
Find Deal
Thu, Dec 11 - Tue, Dec 16
American Airlines Logo
10:07 am - 11:59 pmSAN-DSM
11h 52m1 stop
American Airlines Logo
5:10 am - 3:21 pmDSM-SAN
12h 11m1 stop
$335American Airlines
Find Deal
Thu, Dec 11 - Mon, Dec 15
Southwest Logo
10:50 am - 9:35 pmSAN-DSM
8h 45m1 stop
Southwest Logo
4:40 pm - 10:20 pmDSM-SAN
7h 40m2 stops
$343Southwest
Find Deal
Tue, Dec 16 - Mon, Jan 19
Southwest Logo
10:30 am - 7:55 pmSAN-DSM
7h 25m2 stops
Southwest Logo
4:40 pm - 10:20 pmDSM-SAN
7h 40m2 stops
$348Southwest
Find Deal
Tue, Dec 16 - Mon, Jan 19

United Airlines flights from San Diego to Des Moines

Our best United Airlines deals on San Diego to Des Moines flight tickets
United Airlines
Dec 2
SAN11:02 amSan Diego
7h 46m
2 stops
DSM8:48 pmDes Moines
Dec 9
DSM5:45 amDes Moines
5h 30m
1 stop
SAN9:15 amSan Diego
$302
Find similar
United Airlines
Dec 2
SAN11:02 amSan Diego
7h 46m
2 stops
DSM8:48 pmDes Moines
Dec 9
DSM1:31 pmDes Moines
8h 21m
2 stops
SAN7:52 pmSan Diego
$307
Find similar
United Airlines
Dec 10
SAN11:11 amSan Diego
7h 37m
1 stop
DSM8:48 pmDes Moines
Dec 17
DSM9:00 amDes Moines
11h 28m
2 stops
SAN6:28 pmSan Diego
$382
Find similar

Southwest flights from San Diego to Des Moines

Our best Southwest deals on San Diego to Des Moines flight tickets
Southwest
Dec 16
SAN10:50 amSan Diego
8h 45m
1 stop
DSM9:35 pmDes Moines
Jan 19
DSM4:40 pmDes Moines
7h 40m
2 stops
SAN10:20 pmSan Diego
$343
Find similar
Southwest
Dec 16
SAN10:30 amSan Diego
7h 25m
2 stops
DSM7:55 pmDes Moines
Jan 19
DSM4:40 pmDes Moines
7h 40m
2 stops
SAN10:20 pmSan Diego
$348
Find similar
Southwest
Dec 5
SAN10:30 amSan Diego
7h 25m
2 stops
DSM7:55 pmDes Moines
Dec 8
DSM8:20 amDes Moines
7h 00m
2 stops
SAN1:20 pmSan Diego
$416
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from San Diego to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Fri 12/5

6:34 am-7:03 pm

1 stop10h 29m

Des Moines

Mon 12/8

7:58 pm-11:59 pm

1 stop6h 01m

$127

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Fri 12/5

6:34 am-7:03 pm

1 stop10h 29m

Des Moines

Mon 12/8

7:58 pm-5:53 pm

2 stops23h 55m

$158

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Wed 12/10

7:50 am-5:03 pm

1 stop7h 13m

Des Moines

Wed 12/17

10:20 am-6:21 pm

1 stop10h 01m

$297

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 12/11

6:20 am-5:03 pm

1 stop8h 43m

Des Moines

Tue 12/16

11:23 am-6:18 pm

1 stop8h 55m

$301

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Tue 12/2

11:02 am-8:48 pm

2 stops7h 46m

Des Moines

Tue 12/9

5:45 am-9:15 am

1 stop5h 30m

$302

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Tue 12/2

11:02 am-8:48 pm

2 stops7h 46m

Des Moines

Tue 12/9

1:31 pm-7:52 pm

2 stops8h 21m

$307

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 12/11

10:07 am-11:59 pm

1 stop11h 52m

Des Moines

Tue 12/16

3:38 pm-8:16 pm

1 stop6h 38m

$316

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 12/11

10:07 am-11:59 pm

1 stop11h 52m

Des Moines

Mon 12/15

5:10 am-3:21 pm

1 stop12h 11m

$335

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Tue 12/16

10:50 am-9:35 pm

1 stop8h 45m

Des Moines

Mon 1/19

4:40 pm-10:20 pm

2 stops7h 40m

$343

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Tue 12/16

10:30 am-7:55 pm

2 stops7h 25m

Des Moines

Mon 1/19

4:40 pm-10:20 pm

2 stops7h 40m

$348

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from San Diego to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in July, then May is your next best option. Flight prices from San Diego to Des Moines during May average around $339.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from San Diego to Des Moines is on a Sunday. Travelers who choose to depart for Des Moines on a Sunday will often find tickets for as low as $140. Flights from San Diego to Des Moines on a Wednesday will generally be more expensive and average around $436. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from San Diego to Des Moines in the afternoon for as low as $171. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the evening because they tend to be around $562. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest San Diego to Des Moines flight route?

Fly from San Diego to Des Moines for the best San Diego - Des Moines flight prices

How far in advance should I book a flight to Des Moines?

You are more likely to see cheaper flights to Des Moines from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Des Moines for around $405 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Des Moines from San Diego for as low as $198 on momondo.

What cabin class options are available on San Diego to Des Moines flights?

There is only 1 cabin class available to choose from on San Diego to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Des Moines flights?

No. A direct flight is the cheapest option for a flight between San Diego to Des Moines.

How have San Diego to Des Moines flight prices changed over time?

As of November 2025, prices for San Diego to Des Moines flights are approximately 37% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Des Moines (SAN to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Des Moines

Direct flights

None
There are no direct flights from San Diego to Des Moines. There are no popular flight routes from San Diego to Des Moines.
Search flight deals

  • How far is San Diego to Des Moines by plane?

    San Diego and Des Moines are 1426.2 mi apart from one another. Typically, this will take 6h 36m by plane in normal conditions.

  • When did momondo last update prices for flights from San Diego Airport to Des Moines Airport?

    Prices for flights from San Diego Airport to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Des Moines Airport?

  • How old do you have to be to fly from San Diego Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from San Diego to Des Moines?

  • What is the most popular airline from San Diego to Des Moines?

Best airlines flying from San Diego to Des Moines

Compare and see reviews for airlines that fly from San Diego to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $75Free CancellationRating
7.2
696 reviews
Search Allegiant Air flights
DeltaPriceFrom $148Free CancellationRating
7.9
8,004 reviews
Search Delta flights
FrontierPriceFrom $158Free CancellationRating
5.8
3,115 reviews
Search Frontier flights
United AirlinesPriceFrom $286Free CancellationRating
7.4
9,001 reviews
Search United Airlines flights
American AirlinesPriceFrom $286Free CancellationRating
7.2
11,039 reviews
Search American Airlines flights
SouthwestPriceFrom $306Free CancellationRating
8.0
4,239 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Newton
Pella
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Diego to Des Moines?

momondo helps you find the best flight between San Diego and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 12/5
Fri 12/12
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States