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Cheap flights from San Diego to Des Moines from $119

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Diego to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:25 am - 7:35 pmSAN  San Diego-DSM Des Moines
11h 10m1 stop Denver Intl
Frontier Logo
8:30 pm - 3:58 pmDSM  Des Moines-SAN San Diego
21h 28m1 stop Denver Intl
$219Frontier
Mon, Nov 9 - Fri, Nov 13
Frontier Logo
6:25 am - 7:35 pmSAN  San Diego-DSM Des Moines
11h 10m1 stop Denver Intl
Frontier Logo
8:30 pm - 11:57 pmDSM  Des Moines-SAN San Diego
5h 27m1 stop Denver Intl
$246Frontier
Mon, Nov 2 - Fri, Nov 6
Multiple Airlines Logo
6:25 am - 7:30 pmSAN  San Diego-DSM Des Moines
11h 05m1 stop Denver Intl
Multiple Airlines Logo
9:11 pm - 10:11 amDSM  Des Moines-SAN San Diego
39h 00m2 stops Las Vegas Harry Reid Intl Phoenix Sky Harbor Intl
$324Multiple Airlines
Fri, Oct 23 - Mon, Oct 26
Multiple Airlines Logo
1:02 pm - 7:33 pmSAN  San Diego-DSM Des Moines
28h 31m2 stops Phoenix Sky Harbor Intl Denver Intl
Multiple Airlines Logo
9:39 pm - 7:20 amDSM  Des Moines-SAN San Diego
11h 41m1 stop Las Vegas Harry Reid Intl
$340Multiple Airlines
Sat, Nov 21 - Mon, Nov 30
American Airlines Logo
10:40 pm - 8:46 amSAN  San Diego-DSM Des Moines
8h 06m1 stop Chicago O'Hare Intl
American Airlines Logo
9:37 am - 3:41 pmDSM  Des Moines-SAN San Diego
8h 04m1 stop Dallas/Fort Worth
$355American Airlines
Thu, Nov 12 - Sat, Nov 14
American Airlines Logo
6:20 am - 3:11 pmSAN  San Diego-DSM Des Moines
6h 51m1 stop Dallas/Fort Worth
American Airlines Logo
6:14 am - 10:27 amDSM  Des Moines-SAN San Diego
6h 13m1 stop Dallas/Fort Worth
$355American Airlines
Sat, Oct 24 - Tue, Oct 27
United Airlines Logo
4:18 pm - 11:42 pmSAN  San Diego-DSM Des Moines
5h 24m1 stop Denver Intl
United Airlines Logo
9:00 am - 12:56 pmDSM  Des Moines-SAN San Diego
5h 56m1 stop Denver Intl
$355United Airlines
Sat, Nov 14 - Wed, Nov 18
United Airlines Logo
11:00 am - 8:33 pmSAN  San Diego-DSM Des Moines
7h 33m1 stop Denver Intl
United Airlines Logo
9:30 am - 3:12 pmDSM  Des Moines-SAN San Diego
7h 42m1 stop Chicago O'Hare Intl
$355United Airlines
Tue, Dec 1 - Sat, Dec 5
Southwest Logo
12:10 pm - 7:55 pmSAN  San Diego-DSM Des Moines
5h 45m1 stop Denver Intl
Southwest Logo
5:35 am - 11:45 amDSM  Des Moines-SAN San Diego
8h 10m2 stops Chicago Midway Denver Intl
$360Southwest
Sat, Oct 24 - Tue, Oct 27
Southwest Logo
10:40 pm - 11:30 amSAN  San Diego-DSM Des Moines
10h 50m1 stop Chicago Midway
Southwest Logo
7:10 pm - 12:15 amDSM  Des Moines-SAN San Diego
7h 05m2 stops Denver Intl Phoenix Sky Harbor Intl
$366Southwest
Mon, Oct 26 - Thu, Oct 29

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Frontier flights from San Diego to Des Moines

Our best Frontier deals on San Diego to Des Moines flight tickets
Frontier
Nov 9
SAN6:25 amSan Diego
11h 10m
1 stop
DSM7:35 pmDes Moines
Nov 13
DSM8:30 pmDes Moines
21h 28m
1 stop
SAN3:58 pmSan Diego
$219
Frontier
Nov 2
SAN6:25 amSan Diego
11h 10m
1 stop
DSM7:35 pmDes Moines
Nov 6
DSM8:30 pmDes Moines
5h 27m
1 stop
SAN11:57 pmSan Diego
$246
Frontier
Nov 9
SAN6:25 amSan Diego
11h 10m
1 stop
DSM7:35 pmDes Moines
Nov 13
DSM8:30 pmDes Moines
15h 41m
2 stops
SAN10:11 amSan Diego
$260

United Airlines flights from San Diego to Des Moines

Our best United Airlines deals on San Diego to Des Moines flight tickets
United Airlines
Oct 28
SAN6:20 amSan Diego
9h 07m
2 stops
DSM5:27 pmDes Moines
Nov 7
DSM1:27 pmDes Moines
5h 48m
1 stop
SAN5:15 pmSan Diego
$360
United Airlines
Oct 28
SAN8:45 amSan Diego
5h 22m
1 stop
DSM4:07 pmDes Moines
Oct 30
DSM1:27 pmDes Moines
9h 04m
2 stops
SAN8:31 pmSan Diego
$370
United Airlines
Nov 25
SAN4:18 pmSan Diego
5h 24m
1 stop
DSM11:42 pmDes Moines
Nov 26
DSM5:30 amDes Moines
8h 01m
2 stops
SAN11:31 amSan Diego
$381

momondo Fare Finder

 
Use the filters below to find and compare flights from San Diego to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoDes Moines

SAN San Diego - DSM Des Moines

SANDSM

San Diego

Mon 11/9

6:25 am-7:35 pm

1 stop11h 10m

Des Moines

Fri 11/13

8:30 pm-3:58 pm

1 stop21h 28m

$219

San DiegoDes Moines

SAN San Diego - DSM Des Moines

SANDSM

San Diego

Mon 11/2

6:25 am-7:35 pm

1 stop11h 10m

Des Moines

Fri 11/6

8:30 pm-11:57 pm

1 stop5h 27m

$246

San DiegoDes Moines

SAN San Diego - DSM Des Moines

SANDSM

San Diego

Fri 10/23

6:25 am-7:30 pm

1 stop11h 05m

Des Moines

Mon 10/26

9:11 pm-10:11 am

2 stops39h 00m

$324

San DiegoDes Moines

SAN San Diego - DSM Des Moines

SANDSM

San Diego

Sat 11/21

1:02 pm-7:33 pm

2 stops28h 31m

Des Moines

Mon 11/30

9:39 pm-7:20 am

1 stop11h 41m

$340

San DiegoDes Moines

SAN San Diego - DSM Des Moines

SANDSM

San Diego

Thu 11/12

10:40 pm-8:46 am

1 stop8h 06m

Des Moines

Sat 11/14

9:37 am-3:41 pm

1 stop8h 04m

$355

San DiegoDes Moines

SAN San Diego - DSM Des Moines

SANDSM

San Diego

Sat 10/24

6:20 am-3:11 pm

1 stop6h 51m

Des Moines

Tue 10/27

6:14 am-10:27 am

1 stop6h 13m

$355
Quickest round-trip

San DiegoDes Moines

SAN San Diego - DSM Des Moines

SANDSM

San Diego

Sat 11/14

4:18 pm-11:42 pm

1 stop5h 24m

Des Moines

Wed 11/18

9:00 am-12:56 pm

1 stop5h 56m

$355

San DiegoDes Moines

SAN San Diego - DSM Des Moines

SANDSM

San Diego

Tue 12/1

11:00 am-8:33 pm

1 stop7h 33m

Des Moines

Sat 12/5

9:30 am-3:12 pm

1 stop7h 42m

$355

San DiegoDes Moines

SAN San Diego - DSM Des Moines

SANDSM

San Diego

Sat 10/24

12:10 pm-7:55 pm

1 stop5h 45m

Des Moines

Tue 10/27

5:35 am-11:45 am

2 stops8h 10m

$360

San DiegoDes Moines

SAN San Diego - DSM Des Moines

SANDSM

San Diego

Mon 10/26

10:40 pm-11:30 am

1 stop10h 50m

Des Moines

Thu 10/29

7:10 pm-12:15 am

2 stops7h 05m

$366

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from San Diego to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Diego and Des Moines?

Prices are currently low for flights on this route.

Typical prices usually range from $346 to $718.
The lowest price recently found on this route was $219.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in November, then September is your next best option. Flight prices from San Diego to Des Moines during September average around $354.

How have San Diego to Des Moines flight prices changed over time?

As of October 2026, prices for San Diego to Des Moines flights are approximately 146% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Des Moines (SAN to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Des Moines

Best Price Found

$119

Fastest flight time

6h 00m

Direct flights

None
The best one-way flight to Des Moines from San Diego in the past 72 hours is $119. The best round-trip flight deal from San Diego to Des Moines found on momondo in the last 72 hours is $219.
The fastest flight from San Diego to Des Moines takes 6h 00m
There are no direct flights from San Diego to Des Moines. There are no popular flight routes from San Diego to Des Moines.
Search flight deals

Frequently asked questions about flying from San Diego to Des Moines

  • How far is San Diego to Des Moines by plane?

    San Diego and Des Moines are 1426.2 mi apart from one another. Typically, this will take 6h 00m by plane in normal conditions.

  • When did momondo last update prices for flights from San Diego Airport to Des Moines Airport?

    Prices for flights from San Diego Airport to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Des Moines Airport?

  • How old do you have to be to fly from San Diego Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from San Diego to Des Moines?

  • What is the most popular airline from San Diego to Des Moines?

Best airlines flying from San Diego to Des Moines

Compare and see reviews for airlines that fly from San Diego to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $95Free CancellationRating
5.6
2,566 reviews
Search Frontier flights
DeltaPriceFrom $148Free CancellationRating
7.8
8,615 reviews
Search Delta flights
American AirlinesPriceFrom $208Free CancellationRating
7.0
12,096 reviews
Search American Airlines flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
10,270 reviews
Search United Airlines flights
SouthwestPriceFrom $310Free CancellationRating
8.0
4,207 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Osceola
Urbandale
Newton
Boone
Johnston
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Diego to Des Moines?

momondo helps you find the best flight between San Diego and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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