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Cheap flights from San Diego to Des Moines from $89

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Des Moines departing on 3/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from San Diego to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:25 am - 6:42 pm
SAN
-
DSM
10h 17m
1 stop
Frontier Logo
8:21 pm - 9:14 pm
DSM
-
SAN
26h 53m
1 stop
$169Frontier
Thu, Mar 5 - Mon, Mar 9
Frontier Logo
9:18 pm - 7:16 pm
SAN
-
DSM
19h 58m
1 stop
Frontier Logo
8:21 pm - 8:33 pm
DSM
-
SAN
26h 12m
1 stop
$177Frontier
Fri, Mar 13 - Fri, Mar 20
Frontier Logo
6:25 am - 6:42 pm
SAN
-
DSM
10h 17m
1 stop
Frontier Logo
8:21 pm - 2:31 pm
DSM
-
SAN
44h 10m
2 stops
$203Frontier
Thu, Mar 5 - Mon, Mar 9
Frontier Logo
2:50 pm - 7:16 pm
SAN
-
DSM
26h 26m
2 stops
Frontier Logo
8:21 pm - 9:14 pm
DSM
-
SAN
26h 53m
1 stop
$219Frontier
Thu, Mar 26 - Mon, Mar 30
Frontier Logo
6:25 am - 6:42 pm
SAN
-
DSM
10h 17m
1 stop
Frontier Logo
11:00 am - 8:33 pm
DSM
-
SAN
35h 33m
2 stops
$246Frontier
Thu, Mar 5 - Sun, Mar 8
Frontier Logo
9:58 pm - 7:16 pm
SAN
-
DSM
19h 18m
2 stops
Frontier Logo
8:21 pm - 9:14 pm
DSM
-
SAN
26h 53m
1 stop
$251Frontier
Fri, Mar 27 - Mon, Mar 30
Multiple Airlines Logo
6:25 am - 7:16 pm
SAN
-
DSM
10h 51m
1 stop
Multiple Airlines Logo
8:22 pm - 8:33 pm
DSM
-
SAN
26h 11m
2 stops
$268Multiple Airlines
Fri, Mar 13 - Fri, Mar 20
Frontier Logo
9:18 pm - 7:16 pm
SAN
-
DSM
19h 58m
1 stop
Frontier Logo
8:21 pm - 9:14 pm
DSM
-
SAN
26h 53m
1 stop
$273Frontier
Fri, Mar 27 - Mon, Mar 30
Delta Logo
6:15 am - 3:42 pm
SAN
-
DSM
7h 27m
1 stop
Delta Logo
5:20 pm - 11:09 pm
DSM
-
SAN
7h 49m
1 stop
$297Delta
Wed, Mar 25 - Tue, Mar 31
Frontier Logo
6:25 am - 7:16 pm
SAN
-
DSM
10h 51m
1 stop
Frontier Logo
8:21 pm - 9:14 pm
DSM
-
SAN
26h 53m
1 stop
$312Frontier
Sat, Mar 28 - Mon, Mar 30

American Airlines flights from San Diego to Des Moines

Our best American Airlines deals on San Diego to Des Moines flight tickets
American Airlines
Apr 16
SAN3:12 pmSan Diego
6h 37m
1 stop
DSM11:49 pmDes Moines
Apr 20
DSM2:38 pmDes Moines
5h 47m
1 stop
SAN6:25 pmSan Diego
$337
American Airlines
Apr 20
SAN10:40 pmSan Diego
9h 46m
1 stop
DSM10:26 amDes Moines
Apr 23
DSM6:26 pmDes Moines
5h 29m
1 stop
SAN9:55 pmSan Diego
$350
American Airlines
Apr 17
SAN10:40 pmSan Diego
9h 46m
1 stop
DSM10:26 amDes Moines
Apr 20
DSM7:05 pmDes Moines
6h 51m
1 stop
SAN11:56 pmSan Diego
$357

Delta flights from San Diego to Des Moines

Our best Delta deals on San Diego to Des Moines flight tickets
Delta
Mar 25
SAN6:15 amSan Diego
7h 27m
1 stop
DSM3:42 pmDes Moines
Mar 31
DSM5:20 pmDes Moines
7h 49m
1 stop
SAN11:09 pmSan Diego
$297
Delta
Mar 30
SAN10:10 pmSan Diego
9h 36m
1 stop
DSM9:46 amDes Moines
Apr 7
DSM5:20 pmDes Moines
7h 49m
1 stop
SAN11:09 pmSan Diego
$317
Delta
Mar 30
SAN10:10 pmSan Diego
9h 36m
1 stop
DSM9:46 amDes Moines
Apr 7
DSM10:28 amDes Moines
9h 23m
1 stop
SAN5:51 pmSan Diego
$347

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from San Diego to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 3/5

6:25 am-6:42 pm

1 stop10h 17m

Des Moines

Mon 3/9

8:21 pm-9:14 pm

1 stop26h 53m

$169

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Fri 3/13

9:18 pm-7:16 pm

1 stop19h 58m

Des Moines

Fri 3/20

8:21 pm-8:33 pm

1 stop26h 12m

$177

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 3/5

6:25 am-6:42 pm

1 stop10h 17m

Des Moines

Mon 3/9

8:21 pm-2:31 pm

2 stops44h 10m

$203

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 3/26

2:50 pm-7:16 pm

2 stops26h 26m

Des Moines

Mon 3/30

8:21 pm-9:14 pm

1 stop26h 53m

$219

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Thu 3/5

6:25 am-6:42 pm

1 stop10h 17m

Des Moines

Sun 3/8

11:00 am-8:33 pm

2 stops35h 33m

$246

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Fri 3/27

9:58 pm-7:16 pm

2 stops19h 18m

Des Moines

Mon 3/30

8:21 pm-9:14 pm

1 stop26h 53m

$251

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Fri 3/13

6:25 am-7:16 pm

1 stop10h 51m

Des Moines

Fri 3/20

8:22 pm-8:33 pm

2 stops26h 11m

$268

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Fri 3/27

9:18 pm-7:16 pm

1 stop19h 58m

Des Moines

Mon 3/30

8:21 pm-9:14 pm

1 stop26h 53m

$273

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Wed 3/25

6:15 am-3:42 pm

1 stop7h 27m

Des Moines

Tue 3/31

5:20 pm-11:09 pm

1 stop7h 49m

$297

San DiegoDes Moines

SAN - DSM

SANDSM

San Diego

Sat 3/28

6:25 am-7:16 pm

1 stop10h 51m

Des Moines

Mon 3/30

8:21 pm-9:14 pm

1 stop26h 53m

$312

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from San Diego to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in November, then May is your next best option. Flight prices from San Diego to Des Moines during May average around $310.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from San Diego to Des Moines is on a Sunday. Travelers who choose to depart for Des Moines on a Sunday will often find tickets for as low as $140. Flights from San Diego to Des Moines on a Monday will generally be more expensive and average around $171. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest San Diego to Des Moines flight route?

Fly from San Diego to Des Moines for the best San Diego - Des Moines flight prices

What cabin class options are available on San Diego to Des Moines flights?

There is only 1 cabin class available to choose from on San Diego to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Des Moines flights?

No. A direct flight is the cheapest option for a flight between San Diego to Des Moines.

How have San Diego to Des Moines flight prices changed over time?

As of February 2026, prices for San Diego to Des Moines flights are approximately 50% cheaper when compared to flights at the same time last year.

When to book flights from San Diego to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Des Moines (SAN to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Des Moines

Fastest flight time

5h 04m

Direct flights

None
The fastest flight from San Diego to Des Moines takes 5h 04m
There are no direct flights from San Diego to Des Moines. There are no popular flight routes from San Diego to Des Moines.
Search flight deals

  • How far is San Diego to Des Moines by plane?

    San Diego and Des Moines are 1426.2 mi apart from one another. Typically, this will take 5h 04m by plane in normal conditions.

  • When did momondo last update prices for flights from San Diego Airport to Des Moines Airport?

    Prices for flights from San Diego Airport to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Des Moines Airport?

  • How old do you have to be to fly from San Diego Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from San Diego to Des Moines?

  • What is the most popular airline from San Diego to Des Moines?

Best airlines flying from San Diego to Des Moines

Compare and see reviews for airlines that fly from San Diego to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $75Free CancellationRating
7.2
711 reviews
Search Allegiant Air flights
DeltaPriceFrom $148Free CancellationRating
7.9
8,205 reviews
Search Delta flights
FrontierPriceFrom $158Free CancellationRating
5.7
3,051 reviews
Search Frontier flights
SouthwestPriceFrom $247Free CancellationRating
8.0
4,286 reviews
Search Southwest flights
United AirlinesPriceFrom $286Free CancellationRating
7.4
9,295 reviews
Search United Airlines flights
American AirlinesPriceFrom $286Free CancellationRating
7.2
11,296 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Boone
Osceola
Norwalk
Oskaloosa
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from San Diego on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Diego to Des Moines?

momondo helps you find the best flight between San Diego and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Diego to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from San Diego are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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