Cheap flights from San Antonio to Knoxville from $125
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Antonio to Knoxville departing on 7/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
Discover deals from 900+ travel sites with momondo.
Save money when you book flights with momondo
Big names and deals
Big names and deals
Search 100s of travel sites to compare prices.Filter for what you want
Filter for what you want
Free Wi-Fi? Stopover? Instantly customize your results.Trusted and free
Trusted and free
We’re completely free to use - no hidden charges or fees.Price Alerts
Price Alerts
Not ready to book? to track prices.Find the cheapest flights from San Antonio to Knoxville
Cheap round-trip flights
Cheap one-way flights
American Airlines flights from San Antonio to Knoxville
Our best American Airlines deals on San Antonio to Knoxville flight tickets
Delta flights from San Antonio to Knoxville
Our best Delta deals on San Antonio to Knoxville flight tickets
See travel insights to Knoxville from
How to get the cheapest flight ticket from San Antonio to Knoxville
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Knoxville?
The month of January is, on average, the cheapest month to fly to Knoxville from San Antonio, with most prices found around $258. If you aren’t able to travel during the month of January, then book flights to Knoxville from San Antonio during September instead. Flights to Knoxville in September, while not as cheap as those in January, still average around $296.
What is the cheapest day to depart on your flight to Knoxville?
The cheapest day to depart from San Antonio to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $288. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from San Antonio to Knoxville for around $510.
What is the cheapest time of day to depart on your flight to Knoxville?
In the evening is the cheapest time of day to fly from San Antonio to Knoxville when you can find flight prices for as low as $268. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $358.
How far in advance should I book a flight to Knoxville?
You are more likely to see cheaper flights to Knoxville from San Antonio when booking 11 weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $354 when searching 11 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from San Antonio for as low as $222 on momondo.
What is the cheapest airline that flies from San Antonio to Knoxville McGhee Tyson?
Delta and United Airlines are the most popular carriers operating from San Antonio to Knoxville McGhee Tyson
What airlines fly to Knoxville?
American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to Knoxville from San Antonio according to our data. American Airlines is the first choice among our users, with 49% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 4 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.
When to book flights from San Antonio to Knoxville
Cheap San Antonio to Knoxville (SAT to TYS) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from San Antonio to Knoxville
How far is San Antonio to Knoxville McGhee Tyson by plane?
A flight from San Antonio to Knoxville McGhee Tyson will travel around 958.1 mi. 4h 31m is a normal flight duration for this route.
When did momondo last update prices for flights from San Antonio Airport to Knoxville McGhee Tyson Airport?
Prices for flights from San Antonio Airport to Knoxville McGhee Tyson Airport were last updated today.
How many operators does momondo search for flights from San Antonio Airport to Knoxville McGhee Tyson Airport?
As of June 2025, there are 3 operators available to choose from for flights from San Antonio Airport to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from San Antonio Airport to Knoxville McGhee Tyson Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Antonio Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from San Antonio to Knoxville?
momondo data reveals that the most frequently booked airline on the route from San Antonio to Knoxville is American Airlines, representing 61% of all bookings. The subsequent popular airlines are Delta at 29% and United Airlines at 10%.
Best airlines flying from San Antonio to Knoxville
Compare and see reviews for airlines that fly from San Antonio to Knoxville with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $236 | Free Cancellation | Rating 8.0 7,950 reviews | |||
| PriceFrom $248 | Free Cancellation | Rating 7.2 10,000 reviews | |||
| PriceFrom $258 | Free Cancellation | Rating 7.4 8,790 reviews |
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from San Antonio to Knoxville?
It is quick and easy to find San Antonio to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.
Can I find flights from San Antonio to Knoxville with flexible booking policies on momondo?
Flights from San Antonio to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.
How can momondo help me find flights from San Antonio to Knoxville?
momondo provides multiple filters to help you find the best flight to Knoxville from San Antonio. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.
I’m not ready to book a flight from San Antonio to Knoxville right now. Can momondo alert me if prices change?
Yes. momondo can track prices for San Antonio to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.