What is the cheapest airline that flies from Roanoke to Florida Keys?

United Airlines is the most popular carrier operating from Roanoke to Florida Keys

When did momondo last update prices for flights from Roanoke Airport to Florida Keys?

Prices for flights from Roanoke Airport to Florida Keys refresh daily.

How many operators does momondo search for flights from Roanoke Airport to Florida Keys?

The number of operators available for flights from Roanoke Airport to Florida Keys is 3 as of September 2026.

How old do you have to be to fly from Roanoke Airport to Florida Keys?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$284 Cheap Flights from Roanoke to Florida Keys in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Roanoke to Florida Keys

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:18 pm - 10:37 pmROA Roanoke-MIA Miami

8h 19m1 stop Chicago O'Hare Intl

2:10 pm - 8:39 pmMIA Miami-ROA Roanoke

6h 29m1 stop Chicago O'Hare Intl

$319United Airlines

Wed, Feb 3 - Wed, Feb 24

2:01 pm - 10:31 pmROA Roanoke-MIA Miami

8h 30m1 stop Chicago O'Hare Intl

1:25 pm - 7:07 pmMIA Miami-ROA Roanoke

5h 42m1 stop Washington, D.C. Dulles Intl

$319United Airlines

Sat, Oct 31 - Wed, Nov 4

6:00 am - 10:46 amROA Roanoke-EYW Key West

4h 46m1 stop Atlanta Hartsfield-Jackson

7:40 am - 2:52 pmEYW Key West-ROA Roanoke

7h 12m1 stop Atlanta Hartsfield-Jackson

$319Delta

Fri, Oct 2 - Tue, Oct 6

10:51 am - 9:03 amROA Roanoke-EYW Key West

22h 12m1 stop Tampa St. Petersburg

6:11 pm - 8:22 amEYW Key West-ROA Roanoke

14h 11m1 stop Orlando Sanford Intl

$331Allegiant Air

Sun, Sep 20 - Thu, Sep 24

11:13 am - 5:15 pmROA Roanoke-EYW Key West

6h 02m1 stop Atlanta Hartsfield-Jackson

6:10 pm - 12:27 amEYW Key West-ROA Roanoke

6h 17m1 stop Atlanta Hartsfield-Jackson

$339Delta

Fri, Oct 23 - Fri, Oct 30

6:49 am - 2:59 pmROA Roanoke-MIA Miami

8h 10m1 stop Chicago O'Hare Intl

4:01 pm - 10:59 pmMIA Miami-ROA Roanoke

6h 58m1 stop Chicago O'Hare Intl

$339United Airlines

Wed, Oct 7 - Wed, Oct 14

11:13 am - 5:15 pmROA Roanoke-EYW Key West

6h 02m1 stop Atlanta Hartsfield-Jackson

6:10 pm - 12:27 amEYW Key West-ROA Roanoke

6h 17m1 stop Atlanta Hartsfield-Jackson

$388Delta

Fri, Oct 23 - Fri, Oct 30

3:48 pm - 1:43 pmROA Roanoke-EYW Key West

45h 55m2 stops Orlando Sanford Intl Asheville Regional

8:29 am - 2:58 pmEYW Key West-ROA Roanoke

6h 29m1 stop Orlando Sanford Intl

$393Allegiant Air

Fri, Oct 23 - Fri, Oct 30

11:15 am - 5:55 pmROA Roanoke-EYW Key West

6h 40m1 stop Charlotte Douglas

4:39 pm - 10:48 pmEYW Key West-ROA Roanoke

6h 09m1 stop Charlotte Douglas

$394American Airlines

Wed, Sep 23 - Sat, Sep 26

4:12 pm - 8:51 pmROA Roanoke-MIA Miami

4h 39m1 stop Charlotte Douglas

6:15 am - 10:29 amMIA Miami-ROA Roanoke

4h 14m1 stop Charlotte Douglas

$423American Airlines

Sat, Oct 10 - Sat, Oct 17

Cheap last minute flights

Enter your travel dates to find the best prices.

6:15 am - 11:11 amROA Roanoke-MIA Miami

4h 56m1 stop Washington, D.C. Dulles Intl

1:44 pm - 7:06 pmMIA Miami-ROA Roanoke

5h 22m1 stop Washington, D.C. Dulles Intl

$509United Airlines

Sat, Sep 12 - Tue, Sep 15

6:40 am - 2:51 pmROA Roanoke-MIA Miami

8h 11m1 stop Chicago O'Hare Intl

3:57 pm - 11:06 pmMIA Miami-ROA Roanoke

7h 09m1 stop Chicago O'Hare Intl

$509United Airlines

Sat, Sep 12 - Thu, Sep 17

6:40 am - 2:51 pmROA Roanoke-MIA Miami

8h 11m1 stop Chicago O'Hare Intl

3:57 pm - 11:11 pmMIA Miami-ROA Roanoke

7h 14m1 stop Chicago O'Hare Intl

$509United Airlines

Sat, Sep 12 - Wed, Sep 16

6:15 am - 11:11 amROA Roanoke-MIA Miami

4h 56m1 stop Washington, D.C. Dulles Intl

1:44 pm - 7:06 pmMIA Miami-ROA Roanoke

5h 22m1 stop Washington, D.C. Dulles Intl

$509United Airlines

Sat, Sep 12 - Sun, Sep 13

11:15 am - 5:55 pmROA Roanoke-EYW Key West

6h 40m1 stop Charlotte Douglas

6:27 pm - 10:48 pmEYW Key West-ROA Roanoke

4h 21m1 stop Charlotte Douglas

$519American Airlines

Fri, Sep 11 - Mon, Sep 14

12:11 pm - 5:55 pmROA Roanoke-EYW Key West

5h 44m1 stop Charlotte Douglas

6:31 pm - 10:48 pmEYW Key West-ROA Roanoke

4h 17m1 stop Charlotte Douglas

$519American Airlines

Fri, Sep 11 - Sat, Sep 12

12:11 pm - 5:55 pmROA Roanoke-EYW Key West

5h 44m1 stop Charlotte Douglas

10:21 am - 8:59 pmEYW Key West-ROA Roanoke

10h 38m2 stops Miami Charlotte Douglas

$548American Airlines

Fri, Sep 11 - Sat, Sep 12

11:12 am - 5:23 pmROA Roanoke-EYW Key West

6h 11m1 stop Atlanta Hartsfield-Jackson

7:40 am - 2:51 pmEYW Key West-ROA Roanoke

7h 11m1 stop Atlanta Hartsfield-Jackson

$613Delta

Fri, Sep 11 - Sun, Sep 13

6:00 am - 10:58 amROA Roanoke-MIA Miami

4h 58m1 stop Atlanta Hartsfield-Jackson

4:35 pm - 10:31 amMIA Miami-ROA Roanoke

17h 56m1 stop Atlanta Hartsfield-Jackson

$720Delta

Sat, Sep 12 - Sat, Sep 12

6:00 am - 10:58 amROA Roanoke-MIA Miami

4h 58m1 stop Atlanta Hartsfield-Jackson

4:35 pm - 10:31 amMIA Miami-ROA Roanoke

17h 56m1 stop Atlanta Hartsfield-Jackson

$835Delta

Fri, Sep 11 - Fri, Sep 11

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

American Airlines flights from Roanoke to Florida Keys

Our best American Airlines deals on Roanoke to Florida Keys flight tickets

American Airlines

Sep 23

ROA11:15 amRoanoke

6h 40m

1 stop

EYW5:55 pmKey West

Sep 26

EYW4:39 pmKey West

6h 09m

1 stop

ROA10:48 pmRoanoke

$394

American Airlines

Oct 10

ROA4:12 pmRoanoke

4h 39m

1 stop

MIA8:51 pmMiami

Oct 17

MIA6:15 amMiami

4h 14m

1 stop

ROA10:29 amRoanoke

$423

American Airlines

Sep 22

ROA6:20 amRoanoke

6h 51m

1 stop

EYW1:11 pmKey West

Sep 26

EYW4:39 pmKey West

4h 20m

1 stop

ROA8:59 pmRoanoke

$427

United Airlines flights from Roanoke to Florida Keys

Our best United Airlines deals on Roanoke to Florida Keys flight tickets

United Airlines

Oct 31

ROA2:01 pmRoanoke

8h 30m

1 stop

MIA10:31 pmMiami

Nov 4

MIA1:25 pmMiami

5h 42m

1 stop

ROA7:07 pmRoanoke

$319

United Airlines

Nov 14

ROA2:55 pmRoanoke

7h 49m

1 stop

MIA10:44 pmMiami

Nov 22

MIA7:02 amMiami

6h 24m

1 stop

ROA1:26 pmRoanoke

$339

United Airlines

Oct 14

ROA10:35 amRoanoke

8h 17m

2 stops

MIA6:52 pmMiami

Oct 21

MIA4:01 pmMiami

6h 58m

1 stop

ROA10:59 pmRoanoke

$344

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeMiami

ROA Roanoke - MIA Miami

ROAMIA

Roanoke

Wed 2/3

2:18 pm-10:37 pm

1 stop8h 19m

Miami

Wed 2/24

2:10 pm-8:39 pm

1 stop6h 29m

$319

RoanokeMiami

ROA Roanoke - MIA Miami

ROAMIA

Roanoke

Sat 10/31

2:01 pm-10:31 pm

1 stop8h 30m

Miami

Wed 11/4

1:25 pm-7:07 pm

1 stop5h 42m

$319

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Fri 10/2

6:00 am-10:46 am

1 stop4h 46m

Key West

Tue 10/6

7:40 am-2:52 pm

1 stop7h 12m

$319

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Sun 9/20

10:51 am-9:03 am

1 stop22h 12m

Key West

Thu 9/24

6:11 pm-8:22 am

1 stop14h 11m

$331

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Fri 10/23

11:13 am-5:15 pm

1 stop6h 02m

Key West

Fri 10/30

6:10 pm-12:27 am

1 stop6h 17m

$339

RoanokeMiami

ROA Roanoke - MIA Miami

ROAMIA

Roanoke

Wed 10/7

6:49 am-2:59 pm

1 stop8h 10m

Miami

Wed 10/14

4:01 pm-10:59 pm

1 stop6h 58m

$339

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Fri 10/23

11:13 am-5:15 pm

1 stop6h 02m

Key West

Fri 10/30

6:10 pm-12:27 am

1 stop6h 17m

$388

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Fri 10/23

3:48 pm-1:43 pm

2 stops45h 55m

Key West

Fri 10/30

8:29 am-2:58 pm

1 stop6h 29m

$393

RoanokeKey West

ROA Roanoke - EYW Key West

ROAEYW

Roanoke

Wed 9/23

11:15 am-5:55 pm

1 stop6h 40m

Key West

Sat 9/26

4:39 pm-10:48 pm

1 stop6h 09m

$394

Quickest round-trip

RoanokeMiami

ROA Roanoke - MIA Miami

ROAMIA

Roanoke

Sat 10/10

4:12 pm-8:51 pm

1 stop4h 39m

Miami

Sat 10/17

6:15 am-10:29 am

1 stop4h 14m

$423

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Roanoke to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from Roanoke averaging around $402.

How far in advance should I book a flight from Roanoke to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Roanoke when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $466 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Roanoke for as low as $351 on momondo.

Can stopping save me money on Roanoke to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Roanoke to Florida Keys.

Cheap Roanoke to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Florida Keys

Best Price Found	$284
Fastest flight time	4h 18m
Direct flights	None

The best one-way flight to Florida Keys from Roanoke in the past 72 hours is $284. The best round-trip flight deal from Roanoke to Florida Keys found on momondo in the last 72 hours is $319.

The fastest flight from Roanoke to Florida Keys takes 4h 18m

There are no direct flights from Roanoke to Florida Keys. There are no popular flight routes from Roanoke to Florida Keys.

Search flight deals

Frequently asked questions about flying from Roanoke to Florida Keys

When did momondo last update prices for flights from Roanoke Airport to Florida Keys?
Prices for flights from Roanoke Airport to Florida Keys refresh daily.
How many operators does momondo search for flights from Roanoke Airport to Florida Keys?
The number of operators available for flights from Roanoke Airport to Florida Keys is 3 as of September 2026.
How old do you have to be to fly from Roanoke Airport to Florida Keys?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Roanoke to Florida Keys?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Roanoke to Florida Keys is Canadair (Bombardier) Regional Jet 900 (22.03% of total bookings). The next most popular plane models are Embraer 175 (13.59%), Canadair (Bombardier) Regional Jet CRJ-550 (11.98%), and Airbus A319 (10.76%).

Best airlines flying from Roanoke to Florida Keys

Compare and see reviews for airlines that fly from Roanoke to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 12,045 reviews		Search American Airlines flights
Delta	PriceFrom $268	Free Cancellation	Rating 7.8 8,554 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Florida Keys?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Roanoke to Florida Keys. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Roanoke to Florida Keys with flexible booking policies on momondo?

Flights from Roanoke to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Roanoke to Florida Keys?

Once all potential Roanoke to Florida Keys flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Roanoke to Florida Keys right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florida Keys, momondo offers a useful price alert feature which will track prices for flights to Florida Keys from Roanoke and alert you when they change.