Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Roanoke to Florida Keys from $229

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Florida Keys departing on 1/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Roanoke to Florida Keys

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 12:14 pm
ROA
-
MIA
6h 14m1 stop
Delta Logo
8:15 am - 1:40 pm
MIA
-
ROA
5h 25m1 stop
$229Delta
Wed, Jan 7 - Thu, Jan 15
Allegiant Air Logo
3:45 pm - 9:37 pm
ROA
-
EYW
5h 52m1 stop
Allegiant Air Logo
3:09 pm - 8:19 pm
EYW
-
ROA
5h 10m1 stop
$248Allegiant Air
Thu, Feb 5 - Thu, Feb 12
Delta Logo
6:00 am - 10:40 am
ROA
-
MIA
4h 40m1 stop
Delta Logo
5:50 am - 10:39 am
MIA
-
ROA
4h 49m1 stop
$249Delta
Wed, Jan 7 - Wed, Jan 14
American Airlines Logo
5:14 pm - 10:22 pm
ROA
-
MIA
5h 08m1 stop
American Airlines Logo
7:07 am - 12:09 pm
MIA
-
ROA
5h 02m1 stop
$274American Airlines
Sat, Jan 17 - Sun, Jan 25
American Airlines Logo
3:30 pm - 9:47 pm
ROA
-
EYW
6h 17m1 stop
American Airlines Logo
6:43 pm - 10:53 pm
EYW
-
ROA
4h 10m1 stop
$283American Airlines
Sat, Jan 31 - Wed, Feb 4
Delta Logo
7:05 am - 2:35 pm
ROA
-
MIA
7h 30m1 stop
Delta Logo
7:40 am - 12:04 am
MIA
-
ROA
16h 24m2 stops
$284Delta
Wed, Jan 7 - Thu, Jan 15
American Airlines Logo
3:30 pm - 11:56 pm
ROA
-
EYW
8h 26m2 stops
American Airlines Logo
7:08 am - 1:31 pm
EYW
-
ROA
6h 23m1 stop
$288American Airlines
Sat, Jan 31 - Wed, Feb 4
Multiple Airlines Logo
3:45 pm - 1:30 pm
ROA
-
EYW
21h 45m2 stops
Multiple Airlines Logo
3:09 pm - 8:19 pm
EYW
-
ROA
5h 10m1 stop
$290Multiple Airlines
Sun, Feb 8 - Thu, Feb 12
American Airlines Logo
8:00 am - 6:06 pm
ROA
-
EYW
10h 06m2 stops
American Airlines Logo
12:00 pm - 9:15 pm
EYW
-
ROA
9h 15m2 stops
$293American Airlines
Sat, Jan 31 - Wed, Feb 4
Multiple Airlines Logo
3:53 pm - 11:56 am
ROA
-
EYW
44h 03m2 stops
Multiple Airlines Logo
3:09 pm - 8:19 pm
EYW
-
ROA
5h 10m1 stop
$296Multiple Airlines
Fri, Feb 6 - Thu, Feb 12

Delta flights from Roanoke to Florida Keys

Our best Delta deals on Roanoke to Florida Keys flight tickets
Delta
Jan 7
ROA6:00 amRoanoke
6h 14m
1 stop
MIA12:14 pmMiami
Jan 15
MIA8:15 amMiami
5h 25m
1 stop
ROA1:40 pmRoanoke
$229
Find similar
Delta
Jan 7
ROA6:00 amRoanoke
4h 40m
1 stop
MIA10:40 amMiami
Jan 14
MIA5:50 amMiami
4h 49m
1 stop
ROA10:39 amRoanoke
$249
Find similar
Delta
Jan 7
ROA7:05 amRoanoke
7h 30m
1 stop
MIA2:35 pmMiami
Jan 15
MIA7:40 amMiami
16h 24m
2 stops
ROA12:04 amRoanoke
$284
Find similar

American Airlines flights from Roanoke to Florida Keys

Our best American Airlines deals on Roanoke to Florida Keys flight tickets
American Airlines
Jan 17
ROA5:14 pmRoanoke
5h 08m
1 stop
MIA10:22 pmMiami
Jan 25
MIA7:07 amMiami
5h 02m
1 stop
ROA12:09 pmRoanoke
$274
Find similar
American Airlines
Jan 31
ROA3:30 pmRoanoke
6h 17m
1 stop
EYW9:47 pmKey West
Feb 4
EYW6:43 pmKey West
4h 10m
1 stop
ROA10:53 pmRoanoke
$283
Find similar
American Airlines
Jan 31
ROA3:30 pmRoanoke
8h 26m
2 stops
EYW11:56 pmKey West
Feb 4
EYW7:08 amKey West
6h 23m
1 stop
ROA1:31 pmRoanoke
$288
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Roanoke to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Wed 1/7

6:00 am-12:14 pm

1 stop6h 14m

Miami

Thu 1/15

8:15 am-1:40 pm

1 stop5h 25m

$229

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Thu 2/5

3:45 pm-9:37 pm

1 stop5h 52m

Key West

Thu 2/12

3:09 pm-8:19 pm

1 stop5h 10m

$248

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Wed 1/7

6:00 am-10:40 am

1 stop4h 40m

Miami

Wed 1/14

5:50 am-10:39 am

1 stop4h 49m

$249

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Sat 1/17

5:14 pm-10:22 pm

1 stop5h 08m

Miami

Sun 1/25

7:07 am-12:09 pm

1 stop5h 02m

$274

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Sat 1/31

3:30 pm-9:47 pm

1 stop6h 17m

Key West

Wed 2/4

6:43 pm-10:53 pm

1 stop4h 10m

$283

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Wed 1/7

7:05 am-2:35 pm

1 stop7h 30m

Miami

Thu 1/15

7:40 am-12:04 am

2 stops16h 24m

$284

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Sat 1/31

3:30 pm-11:56 pm

2 stops8h 26m

Key West

Wed 2/4

7:08 am-1:31 pm

1 stop6h 23m

$288

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Sun 2/8

3:45 pm-1:30 pm

2 stops21h 45m

Key West

Thu 2/12

3:09 pm-8:19 pm

1 stop5h 10m

$290

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Sat 1/31

8:00 am-6:06 pm

2 stops10h 06m

Key West

Wed 2/4

12:00 pm-9:15 pm

2 stops9h 15m

$293

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Fri 2/6

3:53 pm-11:56 am

2 stops44h 03m

Key West

Thu 2/12

3:09 pm-8:19 pm

1 stop5h 10m

$296

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

See travel insights to Florida Keys from

How to get the cheapest flight ticket from Roanoke to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from Roanoke averaging around $333.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Roanoke to Florida Keys is on a Wednesday when prices can be found for as low as $405. The most expensive day to fly to Florida Keys is Friday, with ticket prices averaging around $557.

What is the cheapest time of day to depart on your flight to Florida Keys?

According to our data, the cheapest time of day to fly to Florida Keys is in the evening. momondo users have found flights departing from Roanoke to Florida Keys in the evening for as low as $369. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the morning are often more expensive with an average ticket price of $497.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Roanoke when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $421 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Roanoke for as low as $306 on momondo.

Can stopping save me money on Roanoke to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Roanoke to Florida Keys.

Cheap Roanoke to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Florida Keys

Fastest flight time

4h 19m

Direct flights

None
The fastest flight from Roanoke to Florida Keys takes 4h 19m
There are no direct flights from Roanoke to Florida Keys. There are no popular flight routes from Roanoke to Florida Keys.
Search flight deals

  • When did momondo last update prices for flights from Roanoke Airport to Florida Keys?

    Prices for flights from Roanoke Airport to Florida Keys refresh daily.

  • How many operators does momondo search for flights from Roanoke Airport to Florida Keys?

  • How old do you have to be to fly from Roanoke Airport to Florida Keys?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Florida Keys.

  • What documentation or ID do you need to fly to Florida Keys?

    The travel and health documents you'll need for your trip to Florida Keys may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florida Keys. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Roanoke to Florida Keys?

Best airlines flying from Roanoke to Florida Keys

Compare and see reviews for airlines that fly from Roanoke to Florida Keys with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $248Free CancellationRating
7.9
8,005 reviews
Search Delta flights
American AirlinesPriceFrom $248Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Florida Keys?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Roanoke to Florida Keys. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Roanoke to Florida Keys with flexible booking policies on momondo?

Flights from Roanoke to Florida Keys with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Roanoke to Florida Keys?

Once all potential Roanoke to Florida Keys flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Roanoke to Florida Keys right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florida Keys, momondo offers a useful price alert feature which will track prices for flights to Florida Keys from Roanoke and alert you when they change.

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 1/17
Sat 1/24
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Florida Keys

Popular cities in Florida Keys

Popular flights according to clicks in the last 7 days on momondo
Flights to New Yorkfrom $45
Flights to Los Angelesfrom $48
Flights to Miamifrom $49
Flights to Chicagofrom $58
Flights to Orlandofrom $40
Flights to San Franciscofrom $58
Flights to Las Vegasfrom $49
Flights to Washington, D.C.from $57
Flights to Bostonfrom $51
Flights to Atlantafrom $46
Flights to Dallasfrom $57
Flights to Seattlefrom $58