Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Portland, Maine to Greenville from $178

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Greenville departing on 6/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Portland, Maine to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
7:00 am - 11:31 am
PWM
-
GSP
4h 31m
1 stop
Breeze Airways Logo
7:10 pm - 11:24 pm
GSP
-
PWM
4h 14m
1 stop
$253Breeze Airways
Fri, Oct 9 - Fri, Oct 16
Breeze Airways Logo
7:00 am - 11:31 am
PWM
-
GSP
4h 31m
1 stop
Breeze Airways Logo
7:10 pm - 11:24 pm
GSP
-
PWM
4h 14m
1 stop
$258Breeze Airways
Fri, Oct 9 - Fri, Oct 16
Breeze Airways Logo
7:35 am - 11:49 am
PWM
-
GSP
4h 14m
1 stop
Breeze Airways Logo
8:24 pm - 2:20 pm
GSP
-
PWM
17h 56m
2 stops
$337Breeze Airways
Tue, Sep 22 - Sat, Sep 26
American Airlines Logo
7:58 am - 2:18 pm
PWM
-
GSP
6h 20m
1 stop
American Airlines Logo
6:14 am - 12:41 pm
GSP
-
PWM
6h 27m
1 stop
$355American Airlines
Tue, Jun 9 - Tue, Jun 23
United Airlines Logo
6:00 am - 2:20 pm
PWM
-
GSP
8h 20m
2 stops
United Airlines Logo
7:40 pm - 11:51 pm
GSP
-
PWM
4h 11m
1 stop
$360United Airlines
Tue, Jun 9 - Tue, Jun 23
Breeze Airways Logo
9:48 am - 3:47 pm
PWM
-
GSP
5h 59m
1 stop
Breeze Airways Logo
10:37 am - 2:20 pm
GSP
-
PWM
3h 43m
1 stop
$364Breeze Airways
Fri, Oct 30 - Sun, Nov 1
Multiple Airlines Logo
3:11 pm - 7:11 pm
PWM
-
GSP
4h 00m
1 stop
Multiple Airlines Logo
8:19 am - 9:12 am
GSP
-
PWM
24h 53m
1 stop
$365Multiple Airlines
Thu, Jun 4 - Thu, Jun 11
Delta Logo
12:50 pm - 5:53 pm
PWM
-
GSP
5h 03m
1 stop
Delta Logo
5:05 pm - 11:09 pm
GSP
-
PWM
6h 04m
1 stop
$375Delta
Thu, May 28 - Sat, May 30
Breeze Airways Logo
3:11 pm - 7:11 pm
PWM
-
GSP
4h 00m
1 stop
Breeze Airways Logo
10:35 am - 2:26 pm
GSP
-
PWM
3h 51m
1 stop
$377Breeze Airways
Thu, Jul 2 - Sun, Jul 5
Southwest Logo
5:45 am - 4:45 pm
PWM
-
GSP
11h 00m
2 stops
Southwest Logo
6:45 am - 3:00 pm
GSP
-
PWM
8h 15m
2 stops
$381Southwest
Tue, Sep 22 - Sat, Sep 26

American Airlines flights from Portland, Maine to Greenville

Our best American Airlines deals on Portland, Maine to Greenville flight tickets
American Airlines
Jun 9
PWM7:58 amPortland
6h 20m
1 stop
GSP2:18 pmGreenville
Jun 23
GSP6:14 amGreenville
6h 27m
1 stop
PWM12:41 pmPortland
$355
American Airlines
Jun 4
PWM6:00 amPortland
4h 50m
1 stop
GSP10:50 amGreenville
Jun 11
GSP6:14 amGreenville
6h 25m
1 stop
PWM12:39 pmPortland
$391
American Airlines
Jun 13
PWM10:24 amPortland
5h 19m
1 stop
GSP3:43 pmGreenville
Jun 15
GSP7:53 amGreenville
6h 31m
1 stop
PWM2:24 pmPortland
$407

United Airlines flights from Portland, Maine to Greenville

Our best United Airlines deals on Portland, Maine to Greenville flight tickets
United Airlines
Jun 9
PWM6:00 amPortland
8h 20m
2 stops
GSP2:20 pmGreenville
Jun 23
GSP7:40 pmGreenville
4h 11m
1 stop
PWM11:51 pmPortland
$360
United Airlines
Jun 23
PWM5:15 amPortland
4h 40m
1 stop
GSP9:55 amGreenville
Jun 25
GSP7:40 pmGreenville
4h 11m
1 stop
PWM11:51 pmPortland
$371
United Airlines
Jun 23
PWM5:15 amPortland
4h 40m
1 stop
GSP9:55 amGreenville
Jun 26
GSP7:40 pmGreenville
4h 11m
1 stop
PWM11:51 pmPortland
$451

momondo Fare Finder

 
Customize your flight search to find flights from Portland, Maine to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 9, 2026.
Use the filters below to find and compare flights from Portland, Maine to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Fri 10/9

7:00 am-11:31 am

1 stop4h 31m

Greenville

Fri 10/16

7:10 pm-11:24 pm

1 stop4h 14m

$253

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Fri 10/9

7:00 am-11:31 am

1 stop4h 31m

Greenville

Fri 10/16

7:10 pm-11:24 pm

1 stop4h 14m

$258

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Tue 9/22

7:35 am-11:49 am

1 stop4h 14m

Greenville

Sat 9/26

8:24 pm-2:20 pm

2 stops17h 56m

$337

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Tue 6/9

7:58 am-2:18 pm

1 stop6h 20m

Greenville

Tue 6/23

6:14 am-12:41 pm

1 stop6h 27m

$355

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Tue 6/9

6:00 am-2:20 pm

2 stops8h 20m

Greenville

Tue 6/23

7:40 pm-11:51 pm

1 stop4h 11m

$360

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Fri 10/30

9:48 am-3:47 pm

1 stop5h 59m

Greenville

Sun 11/1

10:37 am-2:20 pm

1 stop3h 43m

$364

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Thu 6/4

3:11 pm-7:11 pm

1 stop4h 00m

Greenville

Thu 6/11

8:19 am-9:12 am

1 stop24h 53m

$365

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Thu 5/28

12:50 pm-5:53 pm

1 stop5h 03m

Greenville

Sat 5/30

5:05 pm-11:09 pm

1 stop6h 04m

$375
Quickest round-trip

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Thu 7/2

3:11 pm-7:11 pm

1 stop4h 00m

Greenville

Sun 7/5

10:35 am-2:26 pm

1 stop3h 51m

$377

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Tue 9/22

5:45 am-4:45 pm

2 stops11h 00m

Greenville

Sat 9/26

6:45 am-3:00 pm

2 stops8h 15m

$381

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Greenville from

How to get the cheapest flight ticket from Portland, Maine to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Portland, Maine and Greenville?

What is the cheapest month to fly to Greenville?

The month of September is another great option to travel to Greenville, with average flight prices from Portland, Maine averaging around $258.

How have Portland, Maine to Greenville flight prices changed over time?

When to book flights from Portland, Maine to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Greenville (PWM to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Greenville

Fastest flight time

4h 00m

Direct flights

None
The fastest flight from Portland, Maine to Greenville takes 4h 00m
There are no direct flights from Portland, Maine to Greenville. There are no popular flight routes from Portland, Maine to Greenville.
Search flight deals

Frequently asked questions about flying from Portland, Maine to Greenville

  • How far is Portland to Greenville by plane?

    Portland and Greenville are 887.7 mi apart from one another. 4h 00m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Portland Airport to Greenville Airport?

    Prices for flights from Portland Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from Portland Airport to Greenville Airport?

  • How old do you have to be to fly from Portland Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland, Maine to Greenville?

Best airlines flying from Portland, Maine to Greenville

Compare and see reviews for airlines that fly from Portland, Maine to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $213Free CancellationRating
7.9
8,457 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.1
11,669 reviews
Search American Airlines flights
United AirlinesPriceFrom $309Free CancellationRating
7.4
9,692 reviews
Search United Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Portland to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Portland to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Portland which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Portland to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Portland to Greenville.

I’m not ready to book a flight from Portland to Greenville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Portland to Greenville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Greenville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 6/8
Mon 6/15
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States