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Cheap flights from Portland, Maine to Greenville from $105

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Greenville departing on 8/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Portland, Maine to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
6:00 am - 10:31 amPWM  Portland-GSP Greenville
4h 31m1 stop Cincinnati Cinci./N. Kentucky
Breeze Airways Logo
7:10 pm - 11:24 pmGSP  Greenville-PWM Portland
4h 14m1 stop Cincinnati Cinci./N. Kentucky
$153Breeze Airways
Fri, Sep 11 - Mon, Sep 14
Breeze Airways Logo
7:35 am - 11:49 amPWM  Portland-GSP Greenville
4h 14m1 stop Pittsburgh
Breeze Airways Logo
5:54 pm - 9:37 pmGSP  Greenville-PWM Portland
3h 43m1 stop Pittsburgh
$172Breeze Airways
Tue, Sep 22 - Tue, Sep 29
Multiple Airlines Logo
7:35 am - 11:49 amPWM  Portland-GSP Greenville
4h 14m1 stop Pittsburgh
Multiple Airlines Logo
3:39 pm - 11:24 pmGSP  Greenville-PWM Portland
31h 45m2 stops Orlando Sanford Intl Cincinnati Cinci./N. Kentucky
$309Multiple Airlines
Tue, Sep 15 - Thu, Sep 24
Multiple Airlines Logo
6:30 pm - 11:26 amPWM  Portland-GSP Greenville
40h 56m2 stops Charleston Cincinnati Cinci./N. Kentucky
Multiple Airlines Logo
6:19 pm - 10:38 pmGSP  Greenville-PWM Portland
4h 19m1 stop Cincinnati Cinci./N. Kentucky
$337Multiple Airlines
Wed, Sep 2 - Mon, Sep 7
American Airlines Logo
7:00 am - 11:29 amPWM  Portland-GSP Greenville
4h 29m1 stop Charlotte Douglas
American Airlines Logo
11:02 am - 3:43 pmGSP  Greenville-PWM Portland
4h 41m1 stop Washington, D.C. Reagan-National
$365American Airlines
Wed, Sep 23 - Wed, Oct 7
American Airlines Logo
9:52 am - 5:29 pmPWM  Portland-GSP Greenville
7h 37m1 stop New York LaGuardia
American Airlines Logo
6:28 am - 12:40 pmGSP  Greenville-PWM Portland
6h 12m1 stop New York LaGuardia
$365American Airlines
Wed, Sep 2 - Mon, Sep 7
Delta Logo
5:30 pm - 10:40 pmPWM  Portland-GSP Greenville
5h 10m1 stop New York LaGuardia
Delta Logo
5:00 pm - 11:29 pmGSP  Greenville-PWM Portland
6h 29m1 stop Atlanta Hartsfield-Jackson
$365Delta
Wed, Sep 2 - Wed, Sep 9
Delta Logo
5:29 pm - 10:13 pmPWM  Portland-GSP Greenville
4h 44m1 stop New York LaGuardia
Delta Logo
7:35 am - 12:58 pmGSP  Greenville-PWM Portland
5h 23m1 stop New York LaGuardia
$365Delta
Wed, Nov 11 - Sat, Nov 14
United Airlines Logo
5:08 pm - 10:59 pmPWM  Portland-GSP Greenville
5h 51m1 stop Chicago O'Hare Intl
United Airlines Logo
1:56 pm - 9:51 pmGSP  Greenville-PWM Portland
7h 55m1 stop Chicago O'Hare Intl
$365United Airlines
Tue, Nov 10 - Sat, Nov 14
United Airlines Logo
5:08 pm - 10:59 pmPWM  Portland-GSP Greenville
5h 51m1 stop Chicago O'Hare Intl
United Airlines Logo
10:42 am - 7:02 pmGSP  Greenville-PWM Portland
8h 20m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
$370United Airlines
Tue, Nov 10 - Sat, Nov 14

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Breeze Airways flights from Portland, Maine to Greenville

Our best Breeze Airways deals on Portland, Maine to Greenville flight tickets
Breeze Airways
Sep 11
PWM6:00 amPortland
4h 31m
1 stop
GSP10:31 amGreenville
Sep 14
GSP7:10 pmGreenville
4h 14m
1 stop
PWM11:24 pmPortland
$153
Breeze Airways
Sep 22
PWM7:35 amPortland
4h 14m
1 stop
GSP11:49 amGreenville
Sep 29
GSP5:54 pmGreenville
3h 43m
1 stop
PWM9:37 pmPortland
$172
Breeze Airways
Sep 15
PWM7:35 amPortland
4h 14m
1 stop
GSP11:49 amGreenville
Sep 21
GSP7:10 pmGreenville
4h 14m
1 stop
PWM11:24 pmPortland
$182

United Airlines flights from Portland, Maine to Greenville

Our best United Airlines deals on Portland, Maine to Greenville flight tickets
United Airlines
Nov 11
PWM5:50 amPortland
5h 27m
1 stop
GSP11:17 amGreenville
Nov 15
GSP6:20 amGreenville
8h 07m
2 stops
PWM2:27 pmPortland
$396
United Airlines
Aug 25
PWM3:45 pmPortland
7h 18m
1 stop
GSP11:03 pmGreenville
Aug 29
GSP6:30 amGreenville
8h 04m
1 stop
PWM2:34 pmPortland
$400
United Airlines
Aug 19
PWM5:15 amPortland
4h 35m
1 stop
GSP9:50 amGreenville
Aug 23
GSP2:21 pmGreenville
7h 02m
1 stop
PWM9:23 pmPortland
$546

momondo Fare Finder

 
Customize your flight search to find flights from Portland, Maine to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from Portland, Maine to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandGreenville

PWM Portland - GSP Greenville

PWMGSP

Portland

Fri 9/11

6:00 am-10:31 am

1 stop4h 31m

Greenville

Mon 9/14

7:10 pm-11:24 pm

1 stop4h 14m

$153
Quickest round-trip

PortlandGreenville

PWM Portland - GSP Greenville

PWMGSP

Portland

Tue 9/22

7:35 am-11:49 am

1 stop4h 14m

Greenville

Tue 9/29

5:54 pm-9:37 pm

1 stop3h 43m

$172

PortlandGreenville

PWM Portland - GSP Greenville

PWMGSP

Portland

Tue 9/15

7:35 am-11:49 am

1 stop4h 14m

Greenville

Thu 9/24

3:39 pm-11:24 pm

2 stops31h 45m

$309

PortlandGreenville

PWM Portland - GSP Greenville

PWMGSP

Portland

Wed 9/2

6:30 pm-11:26 am

2 stops40h 56m

Greenville

Mon 9/7

6:19 pm-10:38 pm

1 stop4h 19m

$337

PortlandGreenville

PWM Portland - GSP Greenville

PWMGSP

Portland

Wed 9/23

7:00 am-11:29 am

1 stop4h 29m

Greenville

Wed 10/7

11:02 am-3:43 pm

1 stop4h 41m

$365

PortlandGreenville

PWM Portland - GSP Greenville

PWMGSP

Portland

Wed 9/2

9:52 am-5:29 pm

1 stop7h 37m

Greenville

Mon 9/7

6:28 am-12:40 pm

1 stop6h 12m

$365

PortlandGreenville

PWM Portland - GSP Greenville

PWMGSP

Portland

Wed 9/2

5:30 pm-10:40 pm

1 stop5h 10m

Greenville

Wed 9/9

5:00 pm-11:29 pm

1 stop6h 29m

$365

PortlandGreenville

PWM Portland - GSP Greenville

PWMGSP

Portland

Wed 11/11

5:29 pm-10:13 pm

1 stop4h 44m

Greenville

Sat 11/14

7:35 am-12:58 pm

1 stop5h 23m

$365

PortlandGreenville

PWM Portland - GSP Greenville

PWMGSP

Portland

Tue 11/10

5:08 pm-10:59 pm

1 stop5h 51m

Greenville

Sat 11/14

1:56 pm-9:51 pm

1 stop7h 55m

$365

PortlandGreenville

PWM Portland - GSP Greenville

PWMGSP

Portland

Tue 11/10

5:08 pm-10:59 pm

1 stop5h 51m

Greenville

Sat 11/14

10:42 am-7:02 pm

2 stops8h 20m

$370

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Portland, Maine to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Portland, Maine and Greenville?

Prices are currently low for flights on this route.

Typical prices usually range from $370 to $640.
The lowest price recently found on this route was $153.

What is the cheapest month to fly to Greenville?

The month of September is another great option to travel to Greenville, with average flight prices from Portland, Maine averaging around $258.

How have Portland, Maine to Greenville flight prices changed over time?

When to book flights from Portland, Maine to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Greenville (PWM to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Greenville

Fastest flight time

4h 14m

Direct flights

None
The fastest flight from Portland, Maine to Greenville takes 4h 14m
There are no direct flights from Portland, Maine to Greenville. There are no popular flight routes from Portland, Maine to Greenville.
Search flight deals

Frequently asked questions about flying from Portland, Maine to Greenville

  • How far is Portland to Greenville by plane?

    Portland and Greenville are 887.7 mi apart from one another. 4h 14m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Portland Airport to Greenville Airport?

    Prices for flights from Portland Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from Portland Airport to Greenville Airport?

  • How old do you have to be to fly from Portland Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland, Maine to Greenville?

Best airlines flying from Portland, Maine to Greenville

Compare and see reviews for airlines that fly from Portland, Maine to Greenville with momondo
Airline
Rating
Free Cancellation
Price
Breeze AirwaysPriceFrom $108Free CancellationRating
8.2
304 reviews
Search Breeze Airways flights
DeltaPriceFrom $218Free CancellationRating
7.8
8,496 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.1
11,873 reviews
Search American Airlines flights
United AirlinesPriceFrom $309Free CancellationRating
7.4
10,075 reviews
Search United Airlines flights

  • Breeze Airways Flights From Portland, Maine to Greenville

    Breeze Airways operates around 2 flights from Portland, Maine to Greenville every week. The average price of these flights found in the last 72 hours has been $297, but momondo users have found Breeze Airways deals from Portland, Maine to Greenville from as low as $108 round-trip. Breeze Airways has been scored 8.2/10 in 304 reviews.

  • United Airlines Flights From Portland, Maine to Greenville

    Another popular option for Portland, Maine to Greenville flights is United Airlines (7.4/10, 10,080 ratings). United Airlines flies from Portland, Maine to Greenville around 5 times per week, with deals starting from $309 round-trip and rising to an average price of around $406.

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Portland to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Portland to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Portland which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Portland to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Portland to Greenville.

I’m not ready to book a flight from Portland to Greenville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Portland to Greenville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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