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Cheap flights from Portland, Maine to Greenville from $119

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Greenville departing on 9/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Portland, Maine to Greenville

Cheap round-trip flights

Breeze Airways Logo
3:15 pm - 7:23 pmPWM-GSP
4h 08m1 stop
Breeze Airways Logo
10:33 am - 2:30 pmGSP-PWM
3h 57m1 stop
$154Breeze Airways
Find Deal
Thu, Sep 11 - Sun, Sep 14
American Airlines Logo
6:00 am - 10:52 amPWM-GSP
4h 52m1 stop
American Airlines Logo
6:05 pm - 10:59 pmGSP-PWM
4h 54m1 stop
$237American Airlines
Find Deal
Fri, Aug 22 - Tue, Sep 2
American Airlines Logo
12:27 pm - 4:59 pmPWM-GSP
4h 32m1 stop
American Airlines Logo
9:00 am - 4:50 pmGSP-PWM
7h 50m2 stops
$242American Airlines
Find Deal
Sat, Sep 6 - Sat, Sep 20
American Airlines Logo
12:27 pm - 7:13 pmPWM-GSP
6h 46m2 stops
American Airlines Logo
9:00 am - 4:50 pmGSP-PWM
7h 50m2 stops
$247American Airlines
Find Deal
Sat, Sep 6 - Sat, Sep 20
Southwest Logo
5:50 am - 6:05 pmPWM-GSP
12h 15m2 stops
Southwest Logo
10:25 am - 10:25 pmGSP-PWM
12h 00m2 stops
$333Southwest
Find Deal
Mon, Sep 8 - Tue, Sep 16
United Airlines Logo
4:56 pm - 10:46 pmPWM-GSP
5h 50m1 stop
United Airlines Logo
12:34 pm - 11:03 pmGSP-PWM
10h 29m2 stops
$334United Airlines
Find Deal
Mon, Sep 15 - Mon, Sep 22
Delta Logo
12:40 pm - 11:54 pmPWM-GSP
11h 14m2 stops
Delta Logo
7:45 pm - 12:11 amGSP-PWM
4h 26m1 stop
$337Delta
Find Deal
Fri, Sep 19 - Mon, Sep 22
Delta Logo
12:45 pm - 11:54 pmPWM-GSP
11h 09m2 stops
Delta Logo
5:45 am - 11:51 amGSP-PWM
6h 06m2 stops
$342Delta
Find Deal
Fri, Nov 7 - Wed, Nov 12
Southwest Logo
8:25 am - 6:05 pmPWM-GSP
9h 40m2 stops
Southwest Logo
10:25 am - 10:25 pmGSP-PWM
12h 00m2 stops
$372Southwest
Find Deal
Fri, Aug 22 - Tue, Sep 2
United Airlines Logo
10:05 am - 9:11 pmPWM-GSP
11h 06m2 stops
United Airlines Logo
6:02 am - 1:22 pmGSP-PWM
7h 20m2 stops
$403United Airlines
Find Deal
Mon, Sep 15 - Mon, Sep 22

United Airlines flights from Portland, Maine to Greenville

Our best United Airlines deals on Portland, Maine to Greenville flight tickets
United Airlines
Sep 15
PWM4:56 pmPortland
5h 50m
1 stop
GSP10:46 pmGreenville
Sep 22
GSP12:34 pmGreenville
10h 29m
2 stops
PWM11:03 pmPortland
$334
Find similar
United Airlines
Sep 15
PWM10:05 amPortland
11h 06m
2 stops
GSP9:11 pmGreenville
Sep 22
GSP6:02 amGreenville
7h 20m
2 stops
PWM1:22 pmPortland
$403
Find similar
United Airlines
Aug 22
PWM10:50 amPortland
6h 15m
1 stop
GSP5:05 pmGreenville
Sep 2
GSP6:08 amGreenville
7h 14m
1 stop
PWM1:22 pmPortland
$453
Find similar

Delta flights from Portland, Maine to Greenville

Our best Delta deals on Portland, Maine to Greenville flight tickets
Delta
Sep 19
PWM12:40 pmPortland
11h 14m
2 stops
GSP11:54 pmGreenville
Sep 22
GSP7:45 pmGreenville
4h 26m
1 stop
PWM12:11 amPortland
$337
Find similar
Delta
Nov 7
PWM12:45 pmPortland
11h 09m
2 stops
GSP11:54 pmGreenville
Nov 12
GSP5:45 amGreenville
6h 06m
2 stops
PWM11:51 amPortland
$342
Find similar
Delta
Sep 8
PWM6:00 amPortland
4h 24m
1 stop
GSP10:24 amGreenville
Sep 16
GSP6:00 amGreenville
4h 54m
1 stop
PWM10:54 amPortland
$422
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland, Maine to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 1, 2025.
Use the filters below to find and compare flights from Portland, Maine to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Thu 9/11

3:15 pm-7:23 pm

1 stop4h 08m

Greenville

Sun 9/14

10:33 am-2:30 pm

1 stop3h 57m

$154

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Fri 8/22

6:00 am-10:52 am

1 stop4h 52m

Greenville

Tue 9/2

6:05 pm-10:59 pm

1 stop4h 54m

$237

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Sat 9/6

12:27 pm-4:59 pm

1 stop4h 32m

Greenville

Sat 9/20

9:00 am-4:50 pm

2 stops7h 50m

$242

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Sat 9/6

12:27 pm-7:13 pm

2 stops6h 46m

Greenville

Sat 9/20

9:00 am-4:50 pm

2 stops7h 50m

$247

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Mon 9/8

5:50 am-6:05 pm

2 stops12h 15m

Greenville

Tue 9/16

10:25 am-10:25 pm

2 stops12h 00m

$333

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Mon 9/15

4:56 pm-10:46 pm

1 stop5h 50m

Greenville

Mon 9/22

12:34 pm-11:03 pm

2 stops10h 29m

$334

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Fri 9/19

12:40 pm-11:54 pm

2 stops11h 14m

Greenville

Mon 9/22

7:45 pm-12:11 am

1 stop4h 26m

$337

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Fri 11/7

12:45 pm-11:54 pm

2 stops11h 09m

Greenville

Wed 11/12

5:45 am-11:51 am

2 stops6h 06m

$342

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Fri 8/22

8:25 am-6:05 pm

2 stops9h 40m

Greenville

Tue 9/2

10:25 am-10:25 pm

2 stops12h 00m

$372

PortlandGreenville

PWM - GSP

PWMGSP

Portland

Mon 9/15

10:05 am-9:11 pm

2 stops11h 06m

Greenville

Mon 9/22

6:02 am-1:22 pm

2 stops7h 20m

$403

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Portland, Maine to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of January is another great option to travel to Greenville, with average flight prices from Portland, Maine averaging around $336.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Tuesday is the cheapest day to fly to Greenville from Portland, Maine. The lowest ticket price found for a Tuesday departure recently was $371. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $610. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the afternoon. Flights from Portland, Maine to Greenville during this time can be as low as $371. Flights to Greenville are more costly in the morning, with an average ticket price of $415. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

How have Portland, Maine to Greenville flight prices changed over time?

As of August 2025, prices for Portland, Maine to Greenville flights are approximately 7% more expensive when compared to flights at the same time last year.

When to book flights from Portland, Maine to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Greenville (PWM to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Greenville

Best Price Found

$119

Fastest flight time

4h 05m

Direct flights

None

Airports in Greenville

1 airport
The best one-way flight to Greenville from Portland, Maine in the past 72 hours is $119. The best round-trip flight deal from Portland, Maine to Greenville found on momondo in the last 72 hours is $154.
The fastest flight from Portland, Maine to Greenville takes 4h 05m
There are no direct flights from Portland, Maine to Greenville. Popular non-direct route for this connection is Portland Airport - Greenville Airport.
There is 1 airport near Greenville: Greenville (GSP)
Search flight deals

  • How far is Portland to Greenville by plane?

    Portland and Greenville are 887.7 mi apart from one another. 4h 05m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Portland Airport to Greenville Airport?

    Prices for flights from Portland Airport to Greenville Airport refresh daily.

  • How many operators does momondo search for flights from Portland Airport to Greenville Airport?

  • How old do you have to be to fly from Portland Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The required travel and health documents for your Greenville Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Greenville Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland, Maine to Greenville?

Best airlines flying from Portland, Maine to Greenville

Compare and see reviews for airlines that fly from Portland, Maine to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $270Free CancellationRating
8.0
7,981 reviews
Search Delta flights
American AirlinesPriceFrom $275Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $301Free CancellationRating
8.0
4,246 reviews
Search Southwest flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Portland to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Portland to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Portland which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Portland to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Portland to Greenville.

I’m not ready to book a flight from Portland to Greenville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Portland to Greenville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Greenville trip

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