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Cheap flights from Philadelphia to Florence from $429

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Philadelphia to Florence departing on 9/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Philadelphia to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:25 am - 1:18 pm-
4h 53m
American Airlines Logo
5:09 am - 11:39 am-
6h 30m
$473American Airlines
Wed, Sep 30 - Sat, Oct 10
American Airlines Logo
8:35 am - 2:56 pm-
6h 21m
American Airlines Logo
6:22 am - 10:06 am-
3h 44m
$535American Airlines
Sat, Aug 15 - Tue, Aug 18
American Airlines Logo
6:55 pm - 10:58 pm-
4h 03m
American Airlines Logo
5:09 am - 9:37 am-
4h 28m
$563American Airlines
Tue, Sep 29 - Sat, Oct 10
American Airlines Logo
10:30 am - 2:56 pm-
4h 26m
American Airlines Logo
2:37 pm - 6:26 pm-
3h 49m
$569American Airlines
Thu, Sep 3 - Sun, Sep 6
American Airlines Logo
10:30 am - 2:56 pm-
4h 26m
American Airlines Logo
6:24 am - 11:15 am-
4h 51m
$581American Airlines
Fri, Sep 4 - Fri, Sep 18
American Airlines Logo
4:56 pm - 10:58 pm-
6h 02m
American Airlines Logo
5:09 am - 11:39 am-
6h 30m
$607American Airlines
Tue, Sep 29 - Thu, Oct 8
American Airlines Logo
4:56 pm - 10:59 pm-
6h 03m
American Airlines Logo
6:22 am - 3:05 pm-
8h 43m
$612American Airlines
Fri, Aug 28 - Tue, Sep 1
American Airlines Logo
3:25 pm - 10:59 pm-
7h 34m
American Airlines Logo
6:22 am - 3:05 pm-
8h 43m
$617American Airlines
Fri, Aug 28 - Tue, Sep 1
American Airlines Logo
3:41 pm - 10:58 pm-
7h 17m
American Airlines Logo
5:09 am - 11:39 am-
6h 30m
$629American Airlines
Wed, Sep 30 - Sat, Oct 10
American Airlines Logo
3:25 pm - 10:59 pm-
7h 34m
American Airlines Logo
6:22 am - 12:45 pm-
6h 23m
$630American Airlines
Sat, Aug 15 - Wed, Aug 19

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American Airlines flights from Philadelphia to Florence, South Carolina

Our best American Airlines deals on Philadelphia to Florence, South Carolina flight tickets
American Airlines
Sep 30
PHL8:25 amPhiladelphia
4h 53m
1 stop
FLO1:18 pmFlorence
Oct 10
FLO5:09 amFlorence
6h 30m
1 stop
PHL11:39 amPhiladelphia
$473
American Airlines
Aug 15
PHL8:35 amPhiladelphia
6h 21m
1 stop
FLO2:56 pmFlorence
Aug 18
FLO6:22 amFlorence
3h 44m
1 stop
PHL10:06 amPhiladelphia
$535
American Airlines
Sep 29
PHL6:55 pmPhiladelphia
4h 03m
1 stop
FLO10:58 pmFlorence
Oct 10
FLO5:09 amFlorence
4h 28m
1 stop
PHL9:37 amPhiladelphia
$563

momondo Fare Finder

 
Customize your flight search to find flights from Philadelphia to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from Philadelphia to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Wed 9/30

8:25 am-1:18 pm

1 stop4h 53m

Florence

Sat 10/10

5:09 am-11:39 am

1 stop6h 30m

$473

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 8/15

8:35 am-2:56 pm

1 stop6h 21m

Florence

Tue 8/18

6:22 am-10:06 am

1 stop3h 44m

$535

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 9/29

6:55 pm-10:58 pm

1 stop4h 03m

Florence

Sat 10/10

5:09 am-9:37 am

1 stop4h 28m

$563
Quickest round-trip

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Thu 9/3

10:30 am-2:56 pm

1 stop4h 26m

Florence

Sun 9/6

2:37 pm-6:26 pm

1 stop3h 49m

$569

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Fri 9/4

10:30 am-2:56 pm

1 stop4h 26m

Florence

Fri 9/18

6:24 am-11:15 am

1 stop4h 51m

$581

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 9/29

4:56 pm-10:58 pm

1 stop6h 02m

Florence

Thu 10/8

5:09 am-11:39 am

1 stop6h 30m

$607

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Fri 8/28

4:56 pm-10:59 pm

1 stop6h 03m

Florence

Tue 9/1

6:22 am-3:05 pm

2 stops8h 43m

$612

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Fri 8/28

3:25 pm-10:59 pm

2 stops7h 34m

Florence

Tue 9/1

6:22 am-3:05 pm

2 stops8h 43m

$617

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Wed 9/30

3:41 pm-10:58 pm

2 stops7h 17m

Florence

Sat 10/10

5:09 am-11:39 am

1 stop6h 30m

$629

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 8/15

3:25 pm-10:59 pm

2 stops7h 34m

Florence

Wed 8/19

6:22 am-12:45 pm

1 stop6h 23m

$630

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Philadelphia to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Philadelphia to Florence?

American Airlines is the most popular carrier operating from Philadelphia to Florence

What airlines fly to Florence, South Carolina?

American Airlines, United Airlines and Frontier are the top three most popular airlines that fly to Florence, South Carolina from Philadelphia according to our data. American Airlines is the first choice among our users, with 41% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Philadelphia to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Philadelphia to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Philadelphia to Florence, South Carolina (PHL to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Philadelphia to Florence, South Carolina

Fastest flight time

4h 53m

Direct flights

None
The fastest flight from Philadelphia to Florence, South Carolina takes 4h 53m
There are no direct flights from Philadelphia to Florence, South Carolina. There are no popular flight routes from Philadelphia to Florence, South Carolina.
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Frequently asked questions about flying from Philadelphia to Florence, South Carolina

  • How far is Philadelphia to Florence by plane?

    There are 471.6 mi between Philadelphia and Florence. By plane, this route typically takes 4h 53m.

  • When did momondo last update prices for flights from Philadelphia Airport to Florence Airport?

    Prices for flights from Philadelphia Airport to Florence Airport were last updated today.

  • How old do you have to be to fly from Philadelphia Airport to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Philadelphia Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Philadelphia to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Philadelphia to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Philadelphia to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Philadelphia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Philadelphia to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Philadelphia to Florence.

I’m not ready to book a flight from Philadelphia to Florence right now. Can momondo alert me if prices change?

Price alerts on flights to Florence from Philadelphia are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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