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Cheap flights from Philadelphia to Florence from $364

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Philadelphia to Florence departing on 9/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Philadelphia to Florence (PHL-FLO)

Cheap round-trip flights

American Airlines Logo
1:10 pm - 5:12 pmPHL-FLO
4h 02m1 stop
American Airlines Logo
6:14 am - 12:10 pmFLO-PHL
5h 56m1 stop
$414American Airlines
Find Deal
Tue, Sep 23 - Tue, Sep 30
American Airlines Logo
6:50 pm - 11:16 pmPHL-FLO
4h 26m1 stop
American Airlines Logo
6:14 am - 2:32 pmFLO-PHL
8h 18m2 stops
$419American Airlines
Find Deal
Tue, Sep 23 - Tue, Sep 30
American Airlines Logo
9:36 am - 5:12 pmPHL-FLO
7h 36m2 stops
American Airlines Logo
6:14 am - 2:32 pmFLO-PHL
8h 18m2 stops
$424American Airlines
Find Deal
Tue, Sep 23 - Tue, Sep 30
American Airlines Logo
6:50 pm - 11:16 pmPHL-FLO
4h 26m1 stop
American Airlines Logo
5:14 am - 9:09 amFLO-PHL
3h 55m1 stop
$490American Airlines
Find Deal
Wed, Sep 10 - Sun, Sep 14
American Airlines Logo
3:44 pm - 11:16 pmPHL-FLO
7h 32m2 stops
American Airlines Logo
5:14 am - 10:42 amFLO-PHL
5h 28m1 stop
$495American Airlines
Find Deal
Wed, Sep 10 - Sun, Sep 14
American Airlines Logo
6:39 pm - 11:02 pmPHL-FLO
4h 23m1 stop
American Airlines Logo
6:14 am - 10:27 amFLO-PHL
4h 13m1 stop
$727American Airlines
Find Deal
Tue, Sep 2 - Wed, Sep 3
American Airlines Logo
6:39 pm - 11:02 pmPHL-FLO
4h 23m1 stop
American Airlines Logo
6:14 am - 2:32 pmFLO-PHL
8h 18m2 stops
$732American Airlines
Find Deal
Tue, Sep 2 - Wed, Sep 3
American Airlines Logo
7:09 pm - 12:13 amPHL-FLO
5h 04m1 stop
American Airlines Logo
5:37 pm - 11:27 pmFLO-PHL
5h 50m1 stop
$769American Airlines
Find Deal
Sun, Sep 28 - Wed, Oct 1
American Airlines Logo
7:09 pm - 12:13 amPHL-FLO
5h 04m1 stop
American Airlines Logo
6:14 am - 2:32 pmFLO-PHL
8h 18m2 stops
$774American Airlines
Find Deal
Sun, Sep 28 - Wed, Oct 1
American Airlines Logo
9:36 am - 5:12 pmPHL-FLO
7h 36m2 stops
American Airlines Logo
11:18 am - 5:47 pmFLO-PHL
6h 29m2 stops
$775American Airlines
Find Deal
Wed, Sep 10 - Sun, Sep 14

American Airlines flights from Philadelphia to Florence, South Carolina

Our best American Airlines deals on Philadelphia to Florence, South Carolina flight tickets
American Airlines
Sep 23
PHL1:10 pmPhiladelphia
4h 02m
1 stop
FLO5:12 pmFlorence
Sep 30
FLO6:14 amFlorence
5h 56m
1 stop
PHL12:10 pmPhiladelphia
$414
Find similar
American Airlines
Sep 23
PHL6:50 pmPhiladelphia
4h 26m
1 stop
FLO11:16 pmFlorence
Sep 30
FLO6:14 amFlorence
8h 18m
2 stops
PHL2:32 pmPhiladelphia
$419
Find similar
American Airlines
Sep 23
PHL9:36 amPhiladelphia
7h 36m
2 stops
FLO5:12 pmFlorence
Sep 30
FLO6:14 amFlorence
8h 18m
2 stops
PHL2:32 pmPhiladelphia
$424
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Philadelphia to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 27, 2025.
Use the filters below to find and compare flights from Philadelphia to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 9/23

1:10 pm-5:12 pm

1 stop4h 02m

Florence

Tue 9/30

6:14 am-12:10 pm

1 stop5h 56m

$414

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 9/23

6:50 pm-11:16 pm

1 stop4h 26m

Florence

Tue 9/30

6:14 am-2:32 pm

2 stops8h 18m

$419

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 9/23

9:36 am-5:12 pm

2 stops7h 36m

Florence

Tue 9/30

6:14 am-2:32 pm

2 stops8h 18m

$424

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Wed 9/10

6:50 pm-11:16 pm

1 stop4h 26m

Florence

Sun 9/14

5:14 am-9:09 am

1 stop3h 55m

$490

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Wed 9/10

3:44 pm-11:16 pm

2 stops7h 32m

Florence

Sun 9/14

5:14 am-10:42 am

1 stop5h 28m

$495

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 9/2

6:39 pm-11:02 pm

1 stop4h 23m

Florence

Wed 9/3

6:14 am-10:27 am

1 stop4h 13m

$727

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 9/2

6:39 pm-11:02 pm

1 stop4h 23m

Florence

Wed 9/3

6:14 am-2:32 pm

2 stops8h 18m

$732

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sun 9/28

7:09 pm-12:13 am

1 stop5h 04m

Florence

Wed 10/1

5:37 pm-11:27 pm

1 stop5h 50m

$769

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sun 9/28

7:09 pm-12:13 am

1 stop5h 04m

Florence

Wed 10/1

6:14 am-2:32 pm

2 stops8h 18m

$774

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Wed 9/10

9:36 am-5:12 pm

2 stops7h 36m

Florence

Sun 9/14

11:18 am-5:47 pm

2 stops6h 29m

$775

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Philadelphia to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from Philadelphia is on a Friday. momondo users have found tickets for Friday departures for as low as $410. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Monday is the most expensive day to depart from Philadelphia because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $477.

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the afternoon. momondo users have found flights departing from Philadelphia to Florence, South Carolina in the afternoon for as low as $452. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $455 per ticket.

When to book flights from Philadelphia to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Philadelphia to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Philadelphia to Florence, South Carolina (PHL to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Philadelphia to Florence, South Carolina

Direct flights

None
There are no direct flights from Philadelphia to Florence, South Carolina. There are no popular flight routes from Philadelphia to Florence, South Carolina.
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  • How far is Philadelphia to Florence by plane?

    There are 471.6 mi between Philadelphia and Florence. By plane, this route typically takes 4h 02m.

  • When did momondo last update prices for flights from Philadelphia Airport to Florence Airport?

    Prices for flights from Philadelphia Airport to Florence Airport were last updated today.

  • How many operators does momondo search for flights from Philadelphia Airport to Florence Airport?

  • How old do you have to be to fly from Philadelphia Airport to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Philadelphia Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Philadelphia to Florence, South Carolina?

Best airlines flying from Philadelphia to Florence, South Carolina

Compare and see reviews for airlines that fly from Philadelphia to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $345Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Philadelphia to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Philadelphia to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Philadelphia to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Philadelphia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Philadelphia to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Philadelphia to Florence.

I’m not ready to book a flight from Philadelphia to Florence right now. Can momondo alert me if prices change?

Price alerts on flights to Florence from Philadelphia are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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