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Cheap flights from Philadelphia to Florence from $425

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Philadelphia to Florence departing on 11/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Philadelphia to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:49 pm - 10:53 pmPHL-FLO
5h 04m1 stop
American Airlines Logo
6:33 pm - 12:10 amFLO-PHL
5h 37m1 stop
$425American Airlines
Find Deal
Tue, Nov 4 - Sat, Nov 8
American Airlines Logo
2:54 pm - 10:53 pmPHL-FLO
7h 59m2 stops
American Airlines Logo
11:11 am - 2:36 pmFLO-PHL
3h 25m1 stop
$430American Airlines
Find Deal
Tue, Nov 4 - Sat, Nov 8
American Airlines Logo
10:24 am - 2:04 pmPHL-FLO
3h 40m1 stop
American Airlines Logo
11:14 am - 4:38 pmFLO-PHL
5h 24m1 stop
$435American Airlines
Find Deal
Sat, Nov 1 - Tue, Nov 4
American Airlines Logo
10:43 am - 7:47 pmPHL-FLO
9h 04m2 stops
American Airlines Logo
11:14 am - 2:36 pmFLO-PHL
3h 22m1 stop
$440American Airlines
Find Deal
Sat, Nov 1 - Tue, Nov 4
American Airlines Logo
10:43 am - 7:47 pmPHL-FLO
9h 04m2 stops
American Airlines Logo
11:14 am - 5:59 pmFLO-PHL
6h 45m2 stops
$445American Airlines
Find Deal
Sat, Nov 1 - Tue, Nov 4
American Airlines Logo
5:49 pm - 11:41 pmPHL-FLO
5h 52m1 stop
American Airlines Logo
5:35 pm - 11:56 pmFLO-PHL
6h 21m1 stop
$479American Airlines
Find Deal
Fri, Nov 21 - Mon, Nov 24
American Airlines Logo
6:44 pm - 11:38 pmPHL-FLO
4h 54m1 stop
American Airlines Logo
11:09 am - 5:57 pmFLO-PHL
6h 48m1 stop
$483American Airlines
Find Deal
Tue, Mar 24 - Sat, Mar 28
American Airlines Logo
6:16 am - 10:45 amPHL-FLO
4h 29m1 stop
American Airlines Logo
10:29 am - 5:51 pmFLO-PHL
7h 22m2 stops
$484American Airlines
Find Deal
Fri, Nov 21 - Mon, Nov 24
American Airlines Logo
7:00 am - 2:05 pmPHL-FLO
7h 05m2 stops
American Airlines Logo
11:09 am - 4:51 pmFLO-PHL
5h 42m1 stop
$488American Airlines
Find Deal
Tue, Mar 24 - Sat, Mar 28
American Airlines Logo
7:00 am - 2:05 pmPHL-FLO
7h 05m2 stops
American Airlines Logo
11:09 am - 7:30 pmFLO-PHL
8h 21m2 stops
$489American Airlines
Find Deal
Tue, Mar 24 - Sat, Mar 28

American Airlines flights from Philadelphia to Florence, South Carolina

Our best American Airlines deals on Philadelphia to Florence, South Carolina flight tickets
American Airlines
Nov 4
PHL5:49 pmPhiladelphia
5h 04m
1 stop
FLO10:53 pmFlorence
Nov 8
FLO6:33 pmFlorence
5h 37m
1 stop
PHL12:10 amPhiladelphia
$425
Find similar
American Airlines
Nov 4
PHL2:54 pmPhiladelphia
7h 59m
2 stops
FLO10:53 pmFlorence
Nov 8
FLO11:11 amFlorence
3h 25m
1 stop
PHL2:36 pmPhiladelphia
$430
Find similar
American Airlines
Nov 1
PHL10:24 amPhiladelphia
3h 40m
1 stop
FLO2:04 pmFlorence
Nov 4
FLO11:14 amFlorence
5h 24m
1 stop
PHL4:38 pmPhiladelphia
$435
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Philadelphia to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Philadelphia to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 11/4

5:49 pm-10:53 pm

1 stop5h 04m

Florence

Sat 11/8

6:33 pm-12:10 am

1 stop5h 37m

$425

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 11/4

2:54 pm-10:53 pm

2 stops7h 59m

Florence

Sat 11/8

11:11 am-2:36 pm

1 stop3h 25m

$430

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 11/1

10:24 am-2:04 pm

1 stop3h 40m

Florence

Tue 11/4

11:14 am-4:38 pm

1 stop5h 24m

$435

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 11/1

10:43 am-7:47 pm

2 stops9h 04m

Florence

Tue 11/4

11:14 am-2:36 pm

1 stop3h 22m

$440

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 11/1

10:43 am-7:47 pm

2 stops9h 04m

Florence

Tue 11/4

11:14 am-5:59 pm

2 stops6h 45m

$445

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Fri 11/21

5:49 pm-11:41 pm

1 stop5h 52m

Florence

Mon 11/24

5:35 pm-11:56 pm

1 stop6h 21m

$479

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 3/24

6:44 pm-11:38 pm

1 stop4h 54m

Florence

Sat 3/28

11:09 am-5:57 pm

1 stop6h 48m

$483

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Fri 11/21

6:16 am-10:45 am

1 stop4h 29m

Florence

Mon 11/24

10:29 am-5:51 pm

2 stops7h 22m

$484

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 3/24

7:00 am-2:05 pm

2 stops7h 05m

Florence

Sat 3/28

11:09 am-4:51 pm

1 stop5h 42m

$488

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 3/24

7:00 am-2:05 pm

2 stops7h 05m

Florence

Sat 3/28

11:09 am-7:30 pm

2 stops8h 21m

$489

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Philadelphia to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from Philadelphia is on a Friday. momondo users have found tickets for Friday departures for as low as $410. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Monday is the most expensive day to depart from Philadelphia because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $477.

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the afternoon. momondo users have found flights departing from Philadelphia to Florence, South Carolina in the afternoon for as low as $452. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $455 per ticket.

When to book flights from Philadelphia to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Philadelphia to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Philadelphia to Florence, South Carolina (PHL to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Philadelphia to Florence, South Carolina

Direct flights

None
There are no direct flights from Philadelphia to Florence, South Carolina. There are no popular flight routes from Philadelphia to Florence, South Carolina.
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  • How far is Philadelphia to Florence by plane?

    There are 471.6 mi between Philadelphia and Florence. By plane, this route typically takes 3h 40m.

  • When did momondo last update prices for flights from Philadelphia Airport to Florence Airport?

    Prices for flights from Philadelphia Airport to Florence Airport were last updated today.

  • How old do you have to be to fly from Philadelphia Airport to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Philadelphia Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Philadelphia to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Philadelphia to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Philadelphia to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Philadelphia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Philadelphia to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Philadelphia to Florence.

I’m not ready to book a flight from Philadelphia to Florence right now. Can momondo alert me if prices change?

Price alerts on flights to Florence from Philadelphia are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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