Cheap flights from Panama to Detroit from $321

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Detroit departing on 4/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama to Detroit

Recent round-trip flight deals from Panama to Detroit

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:55 am - 9:39 pm
PTY
-
DTW
17h 44m
2 stops
Multiple Airlines Logo
5:20 am - 2:00 pm
DTW
-
PTY
33h 40m
2 stops
$527Multiple Airlines
Tue, Mar 10 - Wed, Mar 18
Multiple Airlines Logo
10:25 am - 9:39 pm
PTY
-
DTW
10h 14m
1 stop
Multiple Airlines Logo
5:20 am - 4:06 pm
DTW
-
PTY
11h 46m
1 stop
$533Multiple Airlines
Wed, Mar 11 - Wed, Mar 18
Multiple Airlines Logo
5:50 pm - 10:37 pm
PTY
-
DTW
27h 47m
3 stops
Multiple Airlines Logo
4:50 pm - 8:50 am
DTW
-
PTY
17h 00m
2 stops
$540Multiple Airlines
Wed, Mar 11 - Wed, Mar 18
Multiple Airlines Logo
5:50 pm - 10:37 pm
PTY
-
DTW
27h 47m
3 stops
Multiple Airlines Logo
6:05 am - 2:00 pm
DTW
-
PTY
32h 55m
3 stops
$554Multiple Airlines
Wed, Mar 11 - Wed, Mar 18
Multiple Airlines Logo
9:33 pm - 6:32 pm
PTY
-
DTW
19h 59m
1 stop
Multiple Airlines Logo
8:15 am - 12:40 am
DTW
-
PTY
17h 25m
2 stops
$559Multiple Airlines
Wed, Mar 11 - Wed, Mar 18
Multiple Airlines Logo
2:55 am - 8:48 pm
PTY
-
DTW
16h 53m
3 stops
Multiple Airlines Logo
2:06 pm - 8:50 am
DTW
-
PTY
19h 44m
3 stops
$577Multiple Airlines
Fri, Mar 13 - Sat, Mar 21
Multiple Airlines Logo
2:55 am - 8:48 pm
PTY
-
DTW
16h 53m
3 stops
Multiple Airlines Logo
4:50 pm - 8:50 am
DTW
-
PTY
17h 00m
2 stops
$583Multiple Airlines
Fri, Mar 13 - Sat, Mar 21
Multiple Airlines Logo
2:55 am - 8:33 pm
PTY
-
DTW
16h 38m
2 stops
Multiple Airlines Logo
4:50 pm - 8:50 am
DTW
-
PTY
17h 00m
2 stops
$629Multiple Airlines
Fri, Mar 13 - Sat, Mar 21
Multiple Airlines Logo
5:50 pm - 10:07 am
PTY
-
DTW
39h 17m
2 stops
Multiple Airlines Logo
9:36 am - 8:34 pm
DTW
-
PTY
11h 58m
1 stop
$636Multiple Airlines
Sat, Mar 14 - Sat, Mar 21
Multiple Airlines Logo
12:03 pm - 9:25 am
PTY
-
DTW
20h 22m
1 stop
Multiple Airlines Logo
5:00 am - 2:55 pm
DTW
-
PTY
10h 55m
2 stops
$648Multiple Airlines
Mon, Jun 1 - Wed, Jul 8

United Airlines flights from Panama to Detroit

Our best United Airlines deals on Panama to Detroit flight tickets
United Airlines
Jun 3
PTY10:00 amPanama City Tocumen Intl
12h 43m
2 stops
DTW11:43 pmDetroit Metropolitan Wayne County
Jul 29
DTW11:00 amDetroit Metropolitan Wayne County
18h 04m
2 stops
PTY4:04 amPanama City Tocumen Intl
$665
United Airlines
Jun 1
PTY9:45 amPanama City Tocumen Intl
9h 28m
1 stop
DTW8:13 pmDetroit Metropolitan Wayne County
Jul 8
DTW6:25 amDetroit Metropolitan Wayne County
10h 47m
1 stop
PTY4:12 pmPanama City Tocumen Intl
$733
United Airlines
Jun 17
PTY7:55 amPanama City Tocumen Intl
14h 48m
2 stops
DTW11:43 pmDetroit Metropolitan Wayne County
Jul 7
DTW9:12 pmDetroit Metropolitan Wayne County
20h 00m
2 stops
PTY4:12 pmPanama City Tocumen Intl
$736

Copa Airlines flights from Panama to Detroit

Our best Copa Airlines deals on Panama to Detroit flight tickets
Copa Airlines
Jun 12
PTY7:25 pmPanama City Tocumen Intl
12h 08m
1 stop
DTW8:33 amDetroit Metropolitan Wayne County
Jul 6
DTW11:00 amDetroit Metropolitan Wayne County
10h 41m
1 stop
PTY8:41 pmPanama City Tocumen Intl
$744
Copa Airlines
Feb 14
PTY10:00 amPanama City Tocumen Intl
13h 59m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
Feb 16
DTW11:00 amDetroit Metropolitan Wayne County
8h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
$1,444
Copa Airlines
Feb 14
PTY10:00 amPanama City Tocumen Intl
10h 22m
1 stop
DTW8:22 pmDetroit Metropolitan Wayne County
Feb 16
DTW9:10 amDetroit Metropolitan Wayne County
10h 28m
2 stops
PTY7:38 pmPanama City Tocumen Intl
$1,449

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Panama to Detroit that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 3/10

2:55 am-9:39 pm

2 stops17h 44m

Detroit Metropolitan Wayne County

Wed 3/18

5:20 am-2:00 pm

2 stops33h 40m

$527

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 3/11

10:25 am-9:39 pm

1 stop10h 14m

Detroit Metropolitan Wayne County

Wed 3/18

5:20 am-4:06 pm

1 stop11h 46m

$533

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 3/11

5:50 pm-10:37 pm

3 stops27h 47m

Detroit Metropolitan Wayne County

Wed 3/18

4:50 pm-8:50 am

2 stops17h 00m

$540

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 3/11

5:50 pm-10:37 pm

3 stops27h 47m

Detroit Metropolitan Wayne County

Wed 3/18

6:05 am-2:00 pm

3 stops32h 55m

$554

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 3/11

9:33 pm-6:32 pm

1 stop19h 59m

Detroit Metropolitan Wayne County

Wed 3/18

8:15 am-12:40 am

2 stops17h 25m

$559

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 3/13

2:55 am-8:48 pm

3 stops16h 53m

Detroit Metropolitan Wayne County

Sat 3/21

2:06 pm-8:50 am

3 stops19h 44m

$577

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 3/13

2:55 am-8:48 pm

3 stops16h 53m

Detroit Metropolitan Wayne County

Sat 3/21

4:50 pm-8:50 am

2 stops17h 00m

$583

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 3/13

2:55 am-8:33 pm

2 stops16h 38m

Detroit Metropolitan Wayne County

Sat 3/21

4:50 pm-8:50 am

2 stops17h 00m

$629

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 3/14

5:50 pm-10:07 am

2 stops39h 17m

Detroit Metropolitan Wayne County

Sat 3/21

9:36 am-8:34 pm

1 stop11h 58m

$636

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 6/1

12:03 pm-9:25 am

1 stop20h 22m

Detroit Metropolitan Wayne County

Wed 7/8

5:00 am-2:55 pm

2 stops10h 55m

$648

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Panama to Detroit

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Panama to Detroit?

United Airlines is the most popular carrier operating from Panama to Detroit

Cheap Panama to Detroit flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Detroit

Fastest flight time

12h 08m

Direct flights

None
The fastest flight from Panama to Detroit takes 12h 08m
There are no direct flights from Panama to Detroit. There are no popular flight routes from Panama to Detroit.
  • When did momondo last update prices for flights from Panama to Detroit?

    Prices for flights from Panama to Detroit are refreshed on a daily basis.

  • How old do you have to be to fly from Panama to Detroit?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama to Detroit.

  • What documentation or ID do you need to fly to Detroit?

    The travel and health documents required for your trip to Detroit can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Detroit. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Roseville
Port Huron

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Detroit?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama to Detroit for you.

Can I find flights from Panama to Detroit with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Detroit from Panama with this policy.

How can momondo help me find flights from Panama to Detroit?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama to Detroit.

I’m not ready to book a flight from Panama to Detroit right now. Can momondo alert me if prices change?

Price alerts on flights to Detroit from Panama are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Sat 3/14
Sat 3/21

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