Cheap flights from Panama to Detroit from $245

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Detroit departing on 4/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama to Detroit

Recent round-trip flight deals from Panama to Detroit

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:10 am - 9:05 pm
PTY
-
DTW
33h 55m
3 stops
Multiple Airlines Logo
8:25 am - 5:00 pm
DTW
-
PTY
33h 35m
3 stops
$499Multiple Airlines
Tue, Apr 21 - Fri, Apr 24
Multiple Airlines Logo
10:10 am - 5:18 pm
PTY
-
DTW
30h 08m
3 stops
Multiple Airlines Logo
9:50 pm - 1:55 am
DTW
-
PTY
29h 05m
3 stops
$545Multiple Airlines
Fri, May 1 - Thu, May 7
Multiple Airlines Logo
10:10 am - 2:51 pm
PTY
-
DTW
27h 41m
3 stops
Multiple Airlines Logo
9:16 am - 12:35 am
DTW
-
PTY
16h 19m
2 stops
$563Multiple Airlines
Sat, May 2 - Thu, May 7
Multiple Airlines Logo
3:10 pm - 2:51 pm
PTY
-
DTW
22h 41m
3 stops
Multiple Airlines Logo
9:50 pm - 1:55 am
DTW
-
PTY
29h 05m
3 stops
$592Multiple Airlines
Sat, May 2 - Thu, May 7
Multiple Airlines Logo
10:10 am - 8:13 pm
PTY
-
DTW
33h 03m
3 stops
Multiple Airlines Logo
9:50 pm - 1:55 am
DTW
-
PTY
29h 05m
3 stops
$597Multiple Airlines
Wed, Apr 29 - Wed, May 6
Multiple Airlines Logo
10:10 am - 10:21 am
PTY
-
DTW
23h 11m
2 stops
Multiple Airlines Logo
8:25 am - 2:15 pm
DTW
-
PTY
30h 50m
3 stops
$599Multiple Airlines
Tue, Apr 21 - Fri, Apr 24
Multiple Airlines Logo
10:10 am - 8:13 pm
PTY
-
DTW
33h 03m
3 stops
Multiple Airlines Logo
9:30 am - 2:15 pm
DTW
-
PTY
29h 45m
2 stops
$600Multiple Airlines
Wed, Apr 29 - Wed, May 6
Multiple Airlines Logo
4:25 am - 10:52 pm
PTY
-
DTW
17h 27m
2 stops
Multiple Airlines Logo
9:16 am - 5:00 pm
DTW
-
PTY
32h 44m
2 stops
$636Multiple Airlines
Sat, May 2 - Thu, May 7
Multiple Airlines Logo
5:30 am - 10:40 pm
PTY
-
DTW
16h 10m
3 stops
Multiple Airlines Logo
10:18 am - 12:35 am
DTW
-
PTY
15h 17m
2 stops
$658Multiple Airlines
Thu, May 14 - Sat, Jun 6
Multiple Airlines Logo
5:30 am - 9:05 pm
PTY
-
DTW
14h 35m
2 stops
Multiple Airlines Logo
8:25 am - 5:00 pm
DTW
-
PTY
33h 35m
2 stops
$670Multiple Airlines
Tue, Apr 21 - Fri, Apr 24

United Airlines flights from Panama to Detroit Metropolitan Wayne County Airport

Our best United Airlines deals on Panama to Detroit Metropolitan Wayne County Airport flight tickets
United Airlines
Jun 17
PTY10:00 amPanama City Tocumen Intl
11h 24m
1 stop
DTW10:24 pmDetroit Metropolitan Wayne County
Jul 7
DTW6:15 amDetroit Metropolitan Wayne County
8h 59m
1 stop
PTY2:14 pmPanama City Tocumen Intl
$819
United Airlines
Jun 17
PTY7:55 amPanama City Tocumen Intl
14h 48m
2 stops
DTW11:43 pmDetroit Metropolitan Wayne County
Jul 7
DTW6:00 amDetroit Metropolitan Wayne County
11h 12m
2 stops
PTY4:12 pmPanama City Tocumen Intl
$823
United Airlines
Jun 11
PTY7:55 amPanama City Tocumen Intl
13h 29m
1 stop
DTW10:24 pmDetroit Metropolitan Wayne County
Oct 30
DTW9:30 amDetroit Metropolitan Wayne County
10h 32m
1 stop
PTY7:02 pmPanama City Tocumen Intl
$837

Copa Airlines flights from Panama to Detroit Metropolitan Wayne County Airport

Our best Copa Airlines deals on Panama to Detroit Metropolitan Wayne County Airport flight tickets
Copa Airlines
Jun 11
PTY7:55 amPanama City Tocumen Intl
9h 04m
1 stop
DTW5:59 pmDetroit Metropolitan Wayne County
Jul 1
DTW6:40 pmDetroit Metropolitan Wayne County
22h 32m
1 stop
PTY4:12 pmPanama City Tocumen Intl
$818
Copa Airlines
Jun 12
PTY8:10 amPanama City Tocumen Intl
13h 04m
1 stop
DTW10:14 pmDetroit Metropolitan Wayne County
Jul 6
DTW8:50 amDetroit Metropolitan Wayne County
12h 51m
1 stop
PTY8:41 pmPanama City Tocumen Intl
$872
Copa Airlines
Jun 17
PTY10:10 pmPanama City Tocumen Intl
10h 42m
1 stop
DTW9:52 amDetroit Metropolitan Wayne County
Jun 23
DTW11:05 amDetroit Metropolitan Wayne County
27h 17m
1 stop
PTY1:22 pmPanama City Tocumen Intl
$951

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Panama to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 4/21

10:10 am-9:05 pm

3 stops33h 55m

Detroit Metropolitan Wayne County

Fri 4/24

8:25 am-5:00 pm

3 stops33h 35m

$499

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 5/1

10:10 am-5:18 pm

3 stops30h 08m

Detroit Metropolitan Wayne County

Thu 5/7

9:50 pm-1:55 am

3 stops29h 05m

$545

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 5/2

10:10 am-2:51 pm

3 stops27h 41m

Detroit Metropolitan Wayne County

Thu 5/7

9:16 am-12:35 am

2 stops16h 19m

$563

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 5/2

3:10 pm-2:51 pm

3 stops22h 41m

Detroit Metropolitan Wayne County

Thu 5/7

9:50 pm-1:55 am

3 stops29h 05m

$592

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 4/29

10:10 am-8:13 pm

3 stops33h 03m

Detroit Metropolitan Wayne County

Wed 5/6

9:50 pm-1:55 am

3 stops29h 05m

$597

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 4/21

10:10 am-10:21 am

2 stops23h 11m

Detroit Metropolitan Wayne County

Fri 4/24

8:25 am-2:15 pm

3 stops30h 50m

$599

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 4/29

10:10 am-8:13 pm

3 stops33h 03m

Detroit Metropolitan Wayne County

Wed 5/6

9:30 am-2:15 pm

2 stops29h 45m

$600

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 5/2

4:25 am-10:52 pm

2 stops17h 27m

Detroit Metropolitan Wayne County

Thu 5/7

9:16 am-5:00 pm

2 stops32h 44m

$636
Quickest round-trip

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 5/14

5:30 am-10:40 pm

3 stops16h 10m

Detroit Metropolitan Wayne County

Sat 6/6

10:18 am-12:35 am

2 stops15h 17m

$658

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 4/21

5:30 am-9:05 pm

2 stops14h 35m

Detroit Metropolitan Wayne County

Fri 4/24

8:25 am-5:00 pm

2 stops33h 35m

$670

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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Cheap Panama to Detroit Metropolitan Wayne County Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Detroit Metropolitan Wayne County Airport

Fastest flight time

11h 11m

Direct flights

None
The fastest flight from Panama to Detroit Metropolitan Wayne County Airport takes 11h 11m
There are no direct flights from Panama to Detroit Metropolitan Wayne County Airport. There are no popular flight routes from Panama to Detroit Metropolitan Wayne County Airport.

Frequently asked questions about flying from Panama to Detroit Metropolitan Wayne County Airport

  • When did momondo last update prices for flights from Panama to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Panama to Detroit Metropolitan Wayne County Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Panama to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The travel and health documents required for your trip to Detroit Metropolitan Wayne County Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Detroit Metropolitan Wayne County Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Frequently asked questions about flying from Panama to Detroit Metropolitan Wayne County Airport

  • How do I get Price Alerts for flights from Panama to Detroit Metropolitan Wayne County Airport?

    You can take advantage of momondo’s Price Alerts by first searching for your flights to Panama from Detroit Metropolitan Wayne County Airport. Flight offers will be shown to you in real-time. From there you can create a Price Alert by using our on-site widget.

  • How can I save money on flights from Panama to Detroit Metropolitan Wayne County Airport with momondo?

    Leverage our AI within our “Price Forecast” tool, which predicts if it’s better to book now or wait until prices decrease. You can strategically pick the best days to fly and save money on your trip by using our “Price Calendar” tool. “Explore” shows an overview of how much it costs to fly to anywhere from a selected city or airport. Our “Discover” content is a great option for travel inspiration and money-saving tips, while “Price Alerts” will update you when prices change, so you can book when fares are right.

  • How does momondo find its flight prices?

    We aggregate our prices from over 700+ competitors from airlines to OTAs. We operate in over 30 markets worldwide to show you a wide range of travel options.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Dearborn
Romulus
Troy
Monroe
Southfield
Livonia
Novi
Port Clinton
Roseville
Port Huron
Sterling Heights
Dundee
Brighton
Ypsilanti
Pontiac
Farmington Hills
Plymouth

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Detroit?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Detroit from Panama.

Can I find flights from Panama to Detroit with flexible booking policies on momondo?

momondo does allow users to show only those flights to Detroit from Panama which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama to Detroit?

Once you have performed a search for Panama to Detroit flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama to Detroit right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama to Detroit flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
Fri 5/1
Fri 5/8

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