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Cheap flights from Panama to Detroit from $415

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Detroit departing on 2/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama to Detroit

Recent round-trip flight deals from Panama to Detroit

Enter your travel dates to find the best prices.
Delta Logo
2:20 pm - 9:24 amPTY-DTW
18h 04m1 stop
Delta Logo
6:30 am - 12:55 pmDTW-PTY
7h 25m1 stop
$791Delta
Find Deal
Fri, Apr 24 - Tue, Apr 28
United Airlines Logo
10:00 am - 11:44 pmPTY-DTW
12h 44m1 stop
United Airlines Logo
2:15 pm - 4:04 amDTW-PTY
14h 49m2 stops
$796United Airlines
Find Deal
Fri, Apr 24 - Tue, Apr 28
American Airlines Logo
2:53 pm - 11:57 pmPTY-DTW
9h 04m1 stop
American Airlines Logo
5:30 am - 1:27 pmDTW-PTY
7h 57m1 stop
$864American Airlines
Find Deal
Thu, Jan 1 - Fri, Jan 30
American Airlines Logo
2:53 pm - 11:57 pmPTY-DTW
9h 04m1 stop
American Airlines Logo
6:00 am - 3:38 pmDTW-PTY
9h 38m2 stops
$869American Airlines
Find Deal
Thu, Jan 1 - Fri, Jan 30
American Airlines Logo
1:55 pm - 8:53 amPTY-DTW
17h 58m2 stops
American Airlines Logo
5:52 pm - 12:15 pmDTW-PTY
19h 23m2 stops
$887American Airlines
Find Deal
Fri, Apr 24 - Tue, Apr 28
American Airlines Logo
2:53 pm - 11:57 pmPTY-DTW
9h 04m1 stop
American Airlines Logo
5:30 am - 3:38 pmDTW-PTY
10h 08m1 stop
$892American Airlines
Find Deal
Thu, Jan 1 - Fri, Jan 30
American Airlines Logo
2:53 pm - 11:57 pmPTY-DTW
9h 04m1 stop
American Airlines Logo
6:00 am - 3:38 pmDTW-PTY
9h 38m2 stops
$897American Airlines
Find Deal
Thu, Jan 1 - Fri, Jan 30
American Airlines Logo
2:53 pm - 12:12 pmPTY-DTW
21h 19m2 stops
American Airlines Logo
6:00 am - 3:38 pmDTW-PTY
9h 38m2 stops
$929American Airlines
Find Deal
Thu, Jan 1 - Fri, Jan 30
Delta Logo
3:37 pm - 8:00 amPTY-DTW
16h 23m1 stop
Delta Logo
8:05 am - 7:59 pmDTW-PTY
11h 54m1 stop
$985Delta
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Mon, Nov 24 - Sat, Nov 29
United Airlines Logo
4:41 pm - 3:27 pmPTY-DTW
22h 46m2 stops
United Airlines Logo
2:17 pm - 2:45 pmDTW-PTY
24h 28m2 stops
$999United Airlines
Find Deal
Mon, Nov 24 - Sat, Nov 29

Delta flights from Panama to Detroit Metropolitan Wayne County Airport

Our best Delta deals on Panama to Detroit Metropolitan Wayne County Airport flight tickets
Delta
Apr 24
PTY2:20 pmPanama City Tocumen Intl
18h 04m
1 stop
DTW9:24 amDetroit Metropolitan Wayne County
Apr 28
DTW6:30 amDetroit Metropolitan Wayne County
7h 25m
1 stop
PTY12:55 pmPanama City Tocumen Intl
$791
Find similar
Delta
Nov 24
PTY3:37 pmPanama City Tocumen Intl
16h 23m
1 stop
DTW8:00 amDetroit Metropolitan Wayne County
Nov 29
DTW8:05 amDetroit Metropolitan Wayne County
11h 54m
1 stop
PTY7:59 pmPanama City Tocumen Intl
$985
Find similar

American Airlines flights from Panama to Detroit Metropolitan Wayne County Airport

Our best American Airlines deals on Panama to Detroit Metropolitan Wayne County Airport flight tickets
American Airlines
Jan 1
PTY2:53 pmPanama City Tocumen Intl
9h 04m
1 stop
DTW11:57 pmDetroit Metropolitan Wayne County
Jan 30
DTW5:30 amDetroit Metropolitan Wayne County
7h 57m
1 stop
PTY1:27 pmPanama City Tocumen Intl
$864
Find similar
American Airlines
Jan 1
PTY2:53 pmPanama City Tocumen Intl
9h 04m
1 stop
DTW11:57 pmDetroit Metropolitan Wayne County
Jan 30
DTW6:00 amDetroit Metropolitan Wayne County
9h 38m
2 stops
PTY3:38 pmPanama City Tocumen Intl
$869
Find similar
American Airlines
Apr 24
PTY1:55 pmPanama City Tocumen Intl
17h 58m
2 stops
DTW8:53 amDetroit Metropolitan Wayne County
Apr 28
DTW5:52 pmDetroit Metropolitan Wayne County
19h 23m
2 stops
PTY12:15 pmPanama City Tocumen Intl
$887
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Panama to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 4/24

2:20 pm-9:24 am

1 stop18h 04m

Detroit Metropolitan Wayne County

Tue 4/28

6:30 am-12:55 pm

1 stop7h 25m

$791

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 4/24

10:00 am-11:44 pm

1 stop12h 44m

Detroit Metropolitan Wayne County

Tue 4/28

2:15 pm-4:04 am

2 stops14h 49m

$796

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/1

2:53 pm-11:57 pm

1 stop9h 04m

Detroit Metropolitan Wayne County

Fri 1/30

5:30 am-1:27 pm

1 stop7h 57m

$864

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/1

2:53 pm-11:57 pm

1 stop9h 04m

Detroit Metropolitan Wayne County

Fri 1/30

6:00 am-3:38 pm

2 stops9h 38m

$869

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 4/24

1:55 pm-8:53 am

2 stops17h 58m

Detroit Metropolitan Wayne County

Tue 4/28

5:52 pm-12:15 pm

2 stops19h 23m

$887

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/1

2:53 pm-11:57 pm

1 stop9h 04m

Detroit Metropolitan Wayne County

Fri 1/30

5:30 am-3:38 pm

1 stop10h 08m

$892

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/1

2:53 pm-11:57 pm

1 stop9h 04m

Detroit Metropolitan Wayne County

Fri 1/30

6:00 am-3:38 pm

2 stops9h 38m

$897

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/1

2:53 pm-12:12 pm

2 stops21h 19m

Detroit Metropolitan Wayne County

Fri 1/30

6:00 am-3:38 pm

2 stops9h 38m

$929

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 11/24

3:37 pm-8:00 am

1 stop16h 23m

Detroit Metropolitan Wayne County

Sat 11/29

8:05 am-7:59 pm

1 stop11h 54m

$985

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 11/24

4:41 pm-3:27 pm

2 stops22h 46m

Detroit Metropolitan Wayne County

Sat 11/29

2:17 pm-2:45 pm

2 stops24h 28m

$999

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Panama to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Panama to Detroit Metropolitan Wayne County Airport is on a Monday when prices can be found for as low as $801. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Sunday is $1,008.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Panama in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $781 when looking at flights departing in the afternoon. Flights to Detroit Metropolitan Wayne County Airport are more costly in the morning, with an average ticket price of $1,008. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Cheap Panama to Detroit Metropolitan Wayne County Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Detroit Metropolitan Wayne County Airport

Direct flights

None
There are no direct flights from Panama to Detroit Metropolitan Wayne County Airport. There are no popular flight routes from Panama to Detroit Metropolitan Wayne County Airport.
Search flight deals

  • When did momondo last update prices for flights from Panama to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Panama to Detroit Metropolitan Wayne County Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Panama to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The travel and health documents required for your trip to Detroit Metropolitan Wayne County Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Detroit Metropolitan Wayne County Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Southfield
Troy
Dearborn
Romulus
Monroe
Novi
Livonia
Port Clinton
Port Huron
Roseville
Sterling Heights
Brighton
Ypsilanti
Pontiac
Dundee
Madison Heights
Royal Oak

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Detroit?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Detroit from Panama.

Can I find flights from Panama to Detroit with flexible booking policies on momondo?

momondo does allow users to show only those flights to Detroit from Panama which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama to Detroit?

Once you have performed a search for Panama to Detroit flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama to Detroit right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama to Detroit flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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