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Cheap flights from Panama to Buffalo from $323

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Buffalo departing on 2/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama to Buffalo

Recent round-trip flight deals from Panama to Buffalo

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:50 pm - 6:46 pm
PTY
-
BUF
22h 56m
2 stops
Multiple Airlines Logo
7:30 pm - 6:55 pm
BUF
-
PTY
24h 25m
2 stops
$554Multiple Airlines
Tue, Mar 3 - Tue, Mar 10
United Airlines Logo
3:30 pm - 10:00 am
PTY
-
BUF
17h 30m
2 stops
United Airlines Logo
5:47 pm - 4:12 pm
BUF
-
PTY
23h 25m
2 stops
$565United Airlines
Tue, Jun 16 - Mon, Jun 22
Copa Airlines Logo
4:41 pm - 8:51 pm
PTY
-
BUF
28h 10m
2 stops
Copa Airlines Logo
6:00 am - 7:02 pm
BUF
-
PTY
14h 02m
1 stop
$581Copa Airlines
Tue, Mar 3 - Tue, Mar 10
United Airlines Logo
3:30 pm - 10:00 am
PTY
-
BUF
17h 30m
2 stops
United Airlines Logo
5:47 pm - 2:14 pm
BUF
-
PTY
21h 27m
2 stops
$618United Airlines
Sat, Jun 13 - Thu, Jun 18
Copa Airlines Logo
7:55 am - 9:02 pm
PTY
-
BUF
12h 07m
2 stops
Copa Airlines Logo
6:00 am - 4:04 am
BUF
-
PTY
23h 04m
1 stop
$635Copa Airlines
Wed, Jun 17 - Sun, Jun 21
United Airlines Logo
3:30 pm - 10:00 am
PTY
-
BUF
17h 30m
2 stops
United Airlines Logo
6:00 am - 6:37 pm
BUF
-
PTY
13h 37m
2 stops
$651United Airlines
Tue, Jun 16 - Thu, Jun 25
Delta Logo
3:15 pm - 11:26 pm
PTY
-
BUF
8h 11m
1 stop
Delta Logo
6:00 am - 1:03 pm
BUF
-
PTY
8h 03m
1 stop
$673Delta
Tue, Mar 3 - Tue, Mar 10
United Airlines Logo
3:30 pm - 4:40 pm
PTY
-
BUF
24h 10m
2 stops
United Airlines Logo
5:47 pm - 4:12 pm
BUF
-
PTY
23h 25m
2 stops
$676United Airlines
Sun, Jun 14 - Thu, Jun 18
Copa Airlines Logo
3:30 pm - 10:55 pm
PTY
-
BUF
30h 25m
2 stops
Copa Airlines Logo
7:55 pm - 7:31 pm
BUF
-
PTY
24h 36m
2 stops
$740Copa Airlines
Sun, Jun 14 - Thu, Jun 18
Multiple Airlines Logo
3:50 pm - 9:02 am
PTY
-
BUF
16h 12m
2 stops
Multiple Airlines Logo
7:58 pm - 10:30 am
BUF
-
PTY
39h 32m
2 stops
$741Multiple Airlines
Sat, Mar 14 - Fri, Mar 27

United Airlines flights from Panama to Buffalo

Our best United Airlines deals on Panama to Buffalo flight tickets
United Airlines
Jun 16
PTY3:30 pmPanama City Tocumen Intl
17h 30m
2 stops
BUF10:00 amBuffalo
Jun 22
BUF5:47 pmBuffalo
23h 25m
2 stops
PTY4:12 pmPanama City Tocumen Intl
$565
United Airlines
Jun 13
PTY3:30 pmPanama City Tocumen Intl
17h 30m
2 stops
BUF10:00 amBuffalo
Jun 18
BUF5:47 pmBuffalo
21h 27m
2 stops
PTY2:14 pmPanama City Tocumen Intl
$618
United Airlines
Jun 16
PTY3:30 pmPanama City Tocumen Intl
17h 30m
2 stops
BUF10:00 amBuffalo
Jun 25
BUF6:00 amBuffalo
13h 37m
2 stops
PTY6:37 pmPanama City Tocumen Intl
$651

JetBlue flights from Panama to Buffalo

Our best JetBlue deals on Panama to Buffalo flight tickets
JetBlue
Jun 14
PTY2:20 pmPanama City Tocumen Intl
8h 38m
1 stop
BUF11:58 pmBuffalo
Jun 18
BUF7:40 pmBuffalo
18h 25m
1 stop
PTY1:05 pmPanama City Tocumen Intl
$777
JetBlue
Jun 13
PTY2:20 pmPanama City Tocumen Intl
8h 38m
1 stop
BUF11:58 pmBuffalo
Jun 18
BUF6:00 amBuffalo
8h 05m
1 stop
PTY1:05 pmPanama City Tocumen Intl
$788

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Panama to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 3/3

7:50 pm-6:46 pm

2 stops22h 56m

Buffalo

Tue 3/10

7:30 pm-6:55 pm

2 stops24h 25m

$554

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 6/16

3:30 pm-10:00 am

2 stops17h 30m

Buffalo

Mon 6/22

5:47 pm-4:12 pm

2 stops23h 25m

$565

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 3/3

4:41 pm-8:51 pm

2 stops28h 10m

Buffalo

Tue 3/10

6:00 am-7:02 pm

1 stop14h 02m

$581

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Sat 6/13

3:30 pm-10:00 am

2 stops17h 30m

Buffalo

Thu 6/18

5:47 pm-2:14 pm

2 stops21h 27m

$618

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Wed 6/17

7:55 am-9:02 pm

2 stops12h 07m

Buffalo

Sun 6/21

6:00 am-4:04 am

1 stop23h 04m

$635

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 6/16

3:30 pm-10:00 am

2 stops17h 30m

Buffalo

Thu 6/25

6:00 am-6:37 pm

2 stops13h 37m

$651

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Tue 3/3

3:15 pm-11:26 pm

1 stop8h 11m

Buffalo

Tue 3/10

6:00 am-1:03 pm

1 stop8h 03m

$673

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Sun 6/14

3:30 pm-4:40 pm

2 stops24h 10m

Buffalo

Thu 6/18

5:47 pm-4:12 pm

2 stops23h 25m

$676

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Sun 6/14

3:30 pm-10:55 pm

2 stops30h 25m

Buffalo

Thu 6/18

7:55 pm-7:31 pm

2 stops24h 36m

$740

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Sat 3/14

3:50 pm-9:02 am

2 stops16h 12m

Buffalo

Fri 3/27

7:58 pm-10:30 am

2 stops39h 32m

$741

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from Panama to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Panama to Buffalo flights?

You could potentially save up to 3% on your flight if you consider stops on a Panama to Buffalo flight.

Cheap Panama to Buffalo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Buffalo

Fastest flight time

12h 59m

Direct flights

None
The fastest flight from Panama to Buffalo takes 12h 59m
There are no direct flights from Panama to Buffalo. There are no popular flight routes from Panama to Buffalo.
Search flight deals

  • When did momondo last update prices for flights from Panama to Buffalo Airport?

    Prices for flights from Panama to Buffalo Airport are updated daily.

  • How old do you have to be to fly from Panama to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The required travel and health documents for your Buffalo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Buffalo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Grand Island
Tonawanda
Williamsville
Orchard Park
Lockport
West Seneca
Bowmansville
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Buffalo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama to Buffalo. momondo saves you time and could save you money on your trip.

Can I find flights from Panama to Buffalo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama to Buffalo flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama to Buffalo?

Once you have performed a search for Panama to Buffalo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama to Buffalo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama to Buffalo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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