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Cheap flights from Panama to Buffalo from $347

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Buffalo departing on 7/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama to Buffalo

Recent round-trip flight deals from Panama to Buffalo

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:50 pm - 8:58 am
PTY
-
BUF
16h 08m
2 stops
Multiple Airlines Logo
2:41 pm - 10:30 am
BUF
-
PTY
20h 49m
2 stops
$599Multiple Airlines
Thu, May 28 - Tue, Jun 2
Multiple Airlines Logo
3:50 pm - 1:57 pm
PTY
-
BUF
21h 07m
2 stops
Multiple Airlines Logo
6:05 am - 10:30 am
BUF
-
PTY
29h 25m
2 stops
$606Multiple Airlines
Thu, May 28 - Sun, May 31
Multiple Airlines Logo
3:50 pm - 8:58 am
PTY
-
BUF
16h 08m
2 stops
Multiple Airlines Logo
8:00 pm - 10:30 am
BUF
-
PTY
15h 30m
2 stops
$643Multiple Airlines
Thu, May 28 - Wed, Jun 3
United Airlines Logo
9:45 am - 10:31 pm
PTY
-
BUF
11h 46m
1 stop
United Airlines Logo
7:00 am - 4:04 am
BUF
-
PTY
22h 04m
2 stops
$704United Airlines
Wed, Jul 1 - Fri, Jul 3
Delta Logo
2:15 pm - 11:59 pm
PTY
-
BUF
8h 44m
1 stop
Delta Logo
6:15 am - 12:50 pm
BUF
-
PTY
7h 35m
1 stop
$718Delta
Thu, May 28 - Sun, May 31
United Airlines Logo
10:55 pm - 9:03 pm
PTY
-
BUF
21h 08m
2 stops
United Airlines Logo
6:00 am - 7:31 pm
BUF
-
PTY
14h 31m
1 stop
$731United Airlines
Fri, May 29 - Tue, Jun 2
United Airlines Logo
9:45 am - 10:31 pm
PTY
-
BUF
11h 46m
1 stop
United Airlines Logo
6:00 am - 7:31 pm
BUF
-
PTY
14h 31m
1 stop
$747United Airlines
Thu, May 21 - Mon, May 25
Multiple Airlines Logo
10:26 am - 10:39 am
PTY
-
BUF
23h 13m
1 stop
Multiple Airlines Logo
2:50 pm - 8:06 am
BUF
-
PTY
18h 16m
2 stops
$821Multiple Airlines
Sat, Jul 18 - Fri, Jul 24
United Airlines Logo
9:45 am - 10:31 pm
PTY
-
BUF
11h 46m
1 stop
United Airlines Logo
6:00 am - 7:31 pm
BUF
-
PTY
14h 31m
1 stop
$842United Airlines
Fri, May 29 - Tue, Jun 2
United Airlines Logo
10:55 pm - 9:53 am
PTY
-
BUF
9h 58m
1 stop
United Airlines Logo
6:04 pm - 4:12 pm
BUF
-
PTY
23h 08m
2 stops
$847United Airlines
Sat, Jul 18 - Fri, Jul 24

United Airlines flights from Panama to Buffalo

Our best United Airlines deals on Panama to Buffalo flight tickets
United Airlines
Jul 1
PTY9:45 amPanama City Tocumen Intl
11h 46m
1 stop
BUF10:31 pmBuffalo
Jul 3
BUF7:00 amBuffalo
22h 04m
2 stops
PTY4:04 amPanama City Tocumen Intl
$704
United Airlines
May 29
PTY10:55 pmPanama City Tocumen Intl
21h 08m
2 stops
BUF9:03 pmBuffalo
Jun 2
BUF6:00 amBuffalo
14h 31m
1 stop
PTY7:31 pmPanama City Tocumen Intl
$731
United Airlines
May 21
PTY9:45 amPanama City Tocumen Intl
11h 46m
1 stop
BUF10:31 pmBuffalo
May 25
BUF6:00 amBuffalo
14h 31m
1 stop
PTY7:31 pmPanama City Tocumen Intl
$747

American Airlines flights from Panama to Buffalo

Our best American Airlines deals on Panama to Buffalo flight tickets
American Airlines
May 28
PTY1:14 pmPanama City Tocumen Intl
9h 42m
2 stops
BUF11:56 pmBuffalo
May 31
BUF7:31 pmBuffalo
17h 43m
3 stops
PTY12:14 pmPanama City Tocumen Intl
$2,526
American Airlines
May 28
PTY1:14 pmPanama City Tocumen Intl
9h 42m
2 stops
BUF11:56 pmBuffalo
Jun 2
BUF7:40 pmBuffalo
17h 34m
3 stops
PTY12:14 pmPanama City Tocumen Intl
$2,891

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Panama to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 5/28

3:50 pm-8:58 am

2 stops16h 08m

Buffalo

Tue 6/2

2:41 pm-10:30 am

2 stops20h 49m

$599

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 5/28

3:50 pm-1:57 pm

2 stops21h 07m

Buffalo

Sun 5/31

6:05 am-10:30 am

2 stops29h 25m

$606

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 5/28

3:50 pm-8:58 am

2 stops16h 08m

Buffalo

Wed 6/3

8:00 pm-10:30 am

2 stops15h 30m

$643

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Wed 7/1

9:45 am-10:31 pm

1 stop11h 46m

Buffalo

Fri 7/3

7:00 am-4:04 am

2 stops22h 04m

$704
Quickest round-trip

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 5/28

2:15 pm-11:59 pm

1 stop8h 44m

Buffalo

Sun 5/31

6:15 am-12:50 pm

1 stop7h 35m

$718

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 5/29

10:55 pm-9:03 pm

2 stops21h 08m

Buffalo

Tue 6/2

6:00 am-7:31 pm

1 stop14h 31m

$731

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 5/21

9:45 am-10:31 pm

1 stop11h 46m

Buffalo

Mon 5/25

6:00 am-7:31 pm

1 stop14h 31m

$747

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Sat 7/18

10:26 am-10:39 am

1 stop23h 13m

Buffalo

Fri 7/24

2:50 pm-8:06 am

2 stops18h 16m

$821

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 5/29

9:45 am-10:31 pm

1 stop11h 46m

Buffalo

Tue 6/2

6:00 am-7:31 pm

1 stop14h 31m

$842

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Sat 7/18

10:55 pm-9:53 am

1 stop9h 58m

Buffalo

Fri 7/24

6:04 pm-4:12 pm

2 stops23h 08m

$847

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Panama to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Panama to Buffalo flights?

You could potentially save up to 28% on your flight if you consider stops on a Panama to Buffalo flight.

Cheap Panama to Buffalo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Buffalo

Fastest flight time

16h 46m

Direct flights

None
The fastest flight from Panama to Buffalo takes 16h 46m
There are no direct flights from Panama to Buffalo. There are no popular flight routes from Panama to Buffalo.
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Frequently asked questions about flying from Panama to Buffalo

  • When did momondo last update prices for flights from Panama to Buffalo Airport?

    Prices for flights from Panama to Buffalo Airport are updated daily.

  • How old do you have to be to fly from Panama to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The required travel and health documents for your Buffalo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Buffalo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Tonawanda
Grand Island
Williamsville
Orchard Park
Bowmansville
West Seneca
Lockport
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Buffalo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama to Buffalo. momondo saves you time and could save you money on your trip.

Can I find flights from Panama to Buffalo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama to Buffalo flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama to Buffalo?

Once you have performed a search for Panama to Buffalo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama to Buffalo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama to Buffalo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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