Latest deals
Insights
FAQs
Price Alerts

Cheap flights from Panama to Buffalo from $328

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Buffalo departing on 9/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Panama to Buffalo

Recent round-trip flight deals from Panama to Buffalo

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:50 pm - 2:37 pm
PTY
-
BUF
21h 47m
2 stops
Multiple Airlines Logo
7:30 pm - 6:55 pm
BUF
-
PTY
23h 25m
2 stops
$590Multiple Airlines
Thu, Jul 30 - Thu, Dec 3
Multiple Airlines Logo
3:50 pm - 2:26 pm
PTY
-
BUF
21h 36m
2 stops
Multiple Airlines Logo
8:00 pm - 10:30 am
BUF
-
PTY
15h 30m
2 stops
$599Multiple Airlines
Thu, Sep 17 - Mon, Sep 21
Multiple Airlines Logo
3:50 pm - 7:52 am
PTY
-
BUF
15h 02m
2 stops
Multiple Airlines Logo
7:05 am - 10:30 am
BUF
-
PTY
27h 25m
2 stops
$607Multiple Airlines
Thu, Jul 30 - Thu, Dec 3
United Airlines Logo
3:30 pm - 9:28 am
PTY
-
BUF
16h 58m
2 stops
United Airlines Logo
7:40 pm - 7:31 pm
BUF
-
PTY
24h 51m
1 stop
$701United Airlines
Thu, Sep 17 - Mon, Sep 21
American Airlines Logo
1:16 pm - 11:18 am
PTY
-
BUF
21h 02m
2 stops
American Airlines Logo
6:56 pm - 12:26 pm
BUF
-
PTY
18h 30m
2 stops
$714American Airlines
Thu, Sep 17 - Mon, Sep 21
United Airlines Logo
3:30 pm - 9:28 am
PTY
-
BUF
16h 58m
2 stops
United Airlines Logo
10:53 am - 4:04 am
BUF
-
PTY
18h 11m
1 stop
$722United Airlines
Thu, Aug 27 - Thu, Sep 3
United Airlines Logo
9:45 am - 11:11 pm
PTY
-
BUF
12h 26m
1 stop
United Airlines Logo
3:52 pm - 7:31 pm
BUF
-
PTY
28h 39m
1 stop
$725United Airlines
Wed, Sep 30 - Sun, Oct 4
Delta Logo
2:23 pm - 11:54 pm
PTY
-
BUF
8h 31m
1 stop
Delta Logo
6:05 am - 12:58 pm
BUF
-
PTY
7h 53m
1 stop
$733Delta
Fri, Sep 18 - Mon, Sep 21
United Airlines Logo
9:45 am - 11:36 pm
PTY
-
BUF
12h 51m
2 stops
United Airlines Logo
3:52 pm - 7:31 pm
BUF
-
PTY
28h 39m
1 stop
$736United Airlines
Wed, Sep 30 - Sun, Oct 4
United Airlines Logo
9:45 am - 9:45 am
PTY
-
BUF
23h 00m
2 stops
United Airlines Logo
7:59 pm - 7:31 pm
BUF
-
PTY
24h 32m
2 stops
$743United Airlines
Wed, Sep 30 - Sun, Oct 4

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

United Airlines flights from Panama to Buffalo

Our best United Airlines deals on Panama to Buffalo flight tickets
United Airlines
Sep 17
PTY3:30 pmPanama City Tocumen Intl
16h 58m
2 stops
BUF9:28 amBuffalo
Sep 21
BUF6:00 amBuffalo
14h 31m
1 stop
PTY7:31 pmPanama City Tocumen Intl
$701
United Airlines
Aug 27
PTY3:30 pmPanama City Tocumen Intl
16h 58m
2 stops
BUF9:28 amBuffalo
Sep 3
BUF10:53 amBuffalo
18h 11m
1 stop
PTY4:04 amPanama City Tocumen Intl
$722
United Airlines
Sep 30
PTY9:45 amPanama City Tocumen Intl
23h 10m
1 stop
BUF9:55 amBuffalo
Oct 4
BUF7:54 pmBuffalo
24h 37m
1 stop
PTY7:31 pmPanama City Tocumen Intl
$725

American Airlines flights from Panama to Buffalo

Our best American Airlines deals on Panama to Buffalo flight tickets
American Airlines
Sep 17
PTY1:16 pmPanama City Tocumen Intl
21h 02m
2 stops
BUF11:18 amBuffalo
Sep 21
BUF6:56 pmBuffalo
18h 30m
2 stops
PTY12:26 pmPanama City Tocumen Intl
$714
American Airlines
Jul 30
PTY1:14 pmPanama City Tocumen Intl
9h 45m
2 stops
BUF11:59 pmBuffalo
Dec 3
BUF7:20 pmBuffalo
18h 28m
3 stops
PTY1:48 pmPanama City Tocumen Intl
$2,478
American Airlines
Jul 30
PTY1:14 pmPanama City Tocumen Intl
9h 45m
2 stops
BUF11:59 pmBuffalo
Dec 3
BUF7:20 pmBuffalo
18h 28m
3 stops
PTY1:48 pmPanama City Tocumen Intl
$2,495

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 13, 2026.
Use the filters below to find and compare flights from Panama to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 7/30

3:50 pm-2:37 pm

2 stops21h 47m

Buffalo

Thu 12/3

7:30 pm-6:55 pm

2 stops23h 25m

$590

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 9/17

3:50 pm-2:26 pm

2 stops21h 36m

Buffalo

Mon 9/21

8:00 pm-10:30 am

2 stops15h 30m

$599

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 7/30

3:50 pm-7:52 am

2 stops15h 02m

Buffalo

Thu 12/3

7:05 am-10:30 am

2 stops27h 25m

$607

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 9/17

3:30 pm-9:28 am

2 stops16h 58m

Buffalo

Mon 9/21

7:40 pm-7:31 pm

1 stop24h 51m

$701

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 9/17

1:16 pm-11:18 am

2 stops21h 02m

Buffalo

Mon 9/21

6:56 pm-12:26 pm

2 stops18h 30m

$714

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 8/27

3:30 pm-9:28 am

2 stops16h 58m

Buffalo

Thu 9/3

10:53 am-4:04 am

1 stop18h 11m

$722

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Wed 9/30

9:45 am-11:11 pm

1 stop12h 26m

Buffalo

Sun 10/4

3:52 pm-7:31 pm

1 stop28h 39m

$725
Quickest round-trip

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 9/18

2:23 pm-11:54 pm

1 stop8h 31m

Buffalo

Mon 9/21

6:05 am-12:58 pm

1 stop7h 53m

$733

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Wed 9/30

9:45 am-11:36 pm

2 stops12h 51m

Buffalo

Sun 10/4

3:52 pm-7:31 pm

1 stop28h 39m

$736

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Wed 9/30

9:45 am-9:45 am

2 stops23h 00m

Buffalo

Sun 10/4

7:59 pm-7:31 pm

2 stops24h 32m

$743

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Buffalo from

How to get the cheapest flight ticket from Panama to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Panama to Buffalo flights?

You could potentially save up to 4% on your flight if you consider stops on a Panama to Buffalo flight.

Cheap Panama to Buffalo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Buffalo

Fastest flight time

8h 30m

Direct flights

None
The fastest flight from Panama to Buffalo takes 8h 30m
There are no direct flights from Panama to Buffalo. There are no popular flight routes from Panama to Buffalo.
Search flight deals

Frequently asked questions about flying from Panama to Buffalo

  • When did momondo last update prices for flights from Panama to Buffalo Airport?

    Prices for flights from Panama to Buffalo Airport are updated daily.

  • How old do you have to be to fly from Panama to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The required travel and health documents for your Buffalo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Buffalo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Tonawanda
Williamsville
Orchard Park
Grand Island
Bowmansville
West Seneca
Lockport
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Buffalo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama to Buffalo. momondo saves you time and could save you money on your trip.

Can I find flights from Panama to Buffalo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama to Buffalo flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama to Buffalo?

Once you have performed a search for Panama to Buffalo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama to Buffalo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama to Buffalo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Buffalo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 8/12
Wed 8/19
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States