Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Panama City to Charleston from $370

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Charleston departing on 9/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Panama City to Charleston

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
3:30 pm - 10:21 pmPTY  Panama City Tocumen Intl-CHS Charleston
29h 51m1 stop Houston George Bush Intcntl
United Airlines Logo
7:00 am - 7:31 pmCHS  Charleston-PTY Panama City Tocumen Intl
13h 31m1 stop Newark
$583United Airlines
Thu, Oct 1 - Wed, Oct 7
United Airlines Logo
3:30 pm - 10:21 pmPTY  Panama City Tocumen Intl-CHS Charleston
29h 51m1 stop Houston George Bush Intcntl
United Airlines Logo
4:58 pm - 2:14 pmCHS  Charleston-PTY Panama City Tocumen Intl
22h 16m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$583United Airlines
Thu, Oct 1 - Tue, Oct 6
United Airlines Logo
3:30 pm - 10:21 pmPTY  Panama City Tocumen Intl-CHS Charleston
29h 51m1 stop Houston George Bush Intcntl
United Airlines Logo
6:30 am - 7:31 pmCHS  Charleston-PTY Panama City Tocumen Intl
14h 01m2 stops Chicago O'Hare Intl Newark
$583United Airlines
Thu, Oct 1 - Wed, Oct 7
United Airlines Logo
3:30 pm - 10:21 pmPTY  Panama City Tocumen Intl-CHS Charleston
29h 51m1 stop Houston George Bush Intcntl
United Airlines Logo
7:00 am - 6:37 pmCHS  Charleston-PTY Panama City Tocumen Intl
12h 37m1 stop Houston George Bush Intcntl
$583United Airlines
Thu, Oct 1 - Tue, Oct 6
United Airlines Logo
3:30 pm - 2:04 pmPTY  Panama City Tocumen Intl-CHS Charleston
21h 34m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
3:00 pm - 2:14 pmCHS  Charleston-PTY Panama City Tocumen Intl
24h 14m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl
$583United Airlines
Thu, Oct 1 - Tue, Oct 6
Multiple Airlines Logo
3:50 pm - 10:17 amPTY  Panama City Tocumen Intl-CHS Charleston
17h 27m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl
Multiple Airlines Logo
11:09 am - 10:30 amCHS  Charleston-PTY Panama City Tocumen Intl
24h 21m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl
$589Multiple Airlines
Sat, Oct 3 - Tue, Oct 6
American Airlines Logo
1:16 pm - 11:43 pmPTY  Panama City Tocumen Intl-CHS Charleston
9h 27m1 stop Miami
American Airlines Logo
6:00 am - 1:02 pmCHS  Charleston-PTY Panama City Tocumen Intl
8h 02m1 stop Miami
$592American Airlines
Fri, Oct 2 - Tue, Oct 6
United Airlines Logo
7:55 am - 9:59 pmPTY  Panama City Tocumen Intl-CHS Charleston
13h 04m1 stop Houston George Bush Intcntl
United Airlines Logo
7:00 am - 7:02 pmCHS  Charleston-PTY Panama City Tocumen Intl
13h 02m1 stop Newark
$592United Airlines
Mon, Oct 26 - Wed, Oct 28
Multiple Airlines Logo
11:25 am - 9:59 amPTY  Panama City Tocumen Intl-CHS Charleston
21h 34m3 stops San José Juan Santamaria Intl Guatemala City La Aurora New York John F Kennedy Intl
Multiple Airlines Logo
8:25 pm - 2:55 pmCHS  Charleston-PTY Panama City Tocumen Intl
18h 30m3 stops New York John F Kennedy Intl Guatemala City La Aurora San José Juan Santamaria Intl
$594Multiple Airlines
Fri, Oct 30 - Sun, Nov 1
American Airlines Logo
1:16 pm - 11:43 pmPTY  Panama City Tocumen Intl-CHS Charleston
9h 27m1 stop Miami
American Airlines Logo
5:37 pm - 1:02 pmCHS  Charleston-PTY Panama City Tocumen Intl
20h 25m2 stops Charlotte Douglas Miami
$597American Airlines
Fri, Oct 2 - Tue, Oct 6

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Panama City to Charleston

Our best American Airlines deals on Panama City to Charleston flight tickets
American Airlines
Oct 2
PTY1:16 pmPanama City Tocumen Intl
9h 27m
1 stop
CHS11:43 pmCharleston
Oct 6
CHS5:37 pmCharleston
20h 25m
2 stops
PTY1:02 pmPanama City Tocumen Intl
$597
American Airlines
Sep 9
PTY1:16 pmPanama City Tocumen Intl
7h 20m
1 stop
CHS9:36 pmCharleston
Sep 11
CHS6:00 amCharleston
7h 16m
1 stop
PTY12:16 pmPanama City Tocumen Intl
$643
American Airlines
Oct 30
PTY2:02 pmPanama City Tocumen Intl
19h 30m
1 stop
CHS10:32 amCharleston
Nov 1
CHS11:41 amCharleston
26h 32m
1 stop
PTY2:13 pmPanama City Tocumen Intl
$667

United Airlines flights from Panama City to Charleston

Our best United Airlines deals on Panama City to Charleston flight tickets
United Airlines
Oct 1
PTY3:30 pmPanama City Tocumen Intl
29h 51m
1 stop
CHS10:21 pmCharleston
Oct 7
CHS6:30 amCharleston
14h 01m
2 stops
PTY7:31 pmPanama City Tocumen Intl
$583
United Airlines
Oct 26
PTY7:55 amPanama City Tocumen Intl
13h 04m
1 stop
CHS9:59 pmCharleston
Oct 28
CHS7:00 amCharleston
13h 02m
1 stop
PTY7:02 pmPanama City Tocumen Intl
$592
United Airlines
Oct 26
PTY7:55 amPanama City Tocumen Intl
13h 04m
1 stop
CHS9:59 pmCharleston
Oct 28
CHS7:00 amCharleston
13h 02m
1 stop
PTY7:02 pmPanama City Tocumen Intl
$613

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Thu 10/1

3:30 pm-10:21 pm

1 stop29h 51m

Charleston

Wed 10/7

7:00 am-7:31 pm

1 stop13h 31m

$583

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Thu 10/1

3:30 pm-10:21 pm

1 stop29h 51m

Charleston

Tue 10/6

4:58 pm-2:14 pm

2 stops22h 16m

$583

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Thu 10/1

3:30 pm-10:21 pm

1 stop29h 51m

Charleston

Wed 10/7

6:30 am-7:31 pm

2 stops14h 01m

$583

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Thu 10/1

3:30 pm-10:21 pm

1 stop29h 51m

Charleston

Tue 10/6

7:00 am-6:37 pm

1 stop12h 37m

$583

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Thu 10/1

3:30 pm-2:04 pm

2 stops21h 34m

Charleston

Tue 10/6

3:00 pm-2:14 pm

2 stops24h 14m

$583

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Sat 10/3

3:50 pm-10:17 am

2 stops17h 27m

Charleston

Tue 10/6

11:09 am-10:30 am

2 stops24h 21m

$589
Quickest round-trip

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Fri 10/2

1:16 pm-11:43 pm

1 stop9h 27m

Charleston

Tue 10/6

6:00 am-1:02 pm

1 stop8h 02m

$592

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Mon 10/26

7:55 am-9:59 pm

1 stop13h 04m

Charleston

Wed 10/28

7:00 am-7:02 pm

1 stop13h 02m

$592

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Fri 10/30

11:25 am-9:59 am

3 stops21h 34m

Charleston

Sun 11/1

8:25 pm-2:55 pm

3 stops18h 30m

$594

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Fri 10/2

1:16 pm-11:43 pm

1 stop9h 27m

Charleston

Tue 10/6

5:37 pm-1:02 pm

2 stops20h 25m

$597

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

See travel insights to Charleston from

How to get the cheapest flight ticket from Panama City to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Charleston?

Prices are currently typical for flights on this route.

Typical prices usually range from $555 to $683.
The lowest price recently found on this route was $583.

What is the cheapest month to fly to Charleston?

The cheapest month to fly to Charleston from Panama City is in December. Flight prices, which tend to average around $376, are often lower during this time because this is during the off-season. The month of October is another great option to travel to Charleston, with average flight prices from Panama City averaging around $392.

When to book flights from Panama City to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Charleston according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Charleston (PTY to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Charleston

Fastest flight time

13h 04m

Direct flights

None
The fastest flight from Panama City to Charleston takes 13h 04m
There are no direct flights from Panama City to Charleston. There are no popular flight routes from Panama City to Charleston.
Search flight deals

Frequently asked questions about flying from Panama City to Charleston

  • How far is Panama City Tocumen Intl to Charleston by plane?

    The distance between Panama City Tocumen Intl and Charleston is about 1643.0 mi. A reasonable flight in good conditions will take 13h 04m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Charleston Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Charleston Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Charleston Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Charleston Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The required travel and health documents for your Charleston Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Charleston Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Charleston?

Best airlines flying from Panama City to Charleston

Compare and see reviews for airlines that fly from Panama City to Charleston with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $404Free CancellationRating
7.1
11,877 reviews
Search American Airlines flights

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
North Charleston
Summerville
Isle of Palms
Mount Pleasant
Kiawah Island
Walterboro
Goose Creek
Santee
Edisto Island
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Charleston?

It is quick and easy to find Panama City to Charleston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charleston that suits you.

Can I find flights from Panama City to Charleston with flexible booking policies on momondo?

momondo does allow users to show only those flights to Charleston from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Charleston?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama City to Charleston.

I’m not ready to book a flight from Panama City to Charleston right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Charleston flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Charleston trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 9/6
Sun 9/13
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States