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Cheap flights from Panama City to Charleston from $376

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Charleston departing on 9/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Delta Logo
2:05 pm - 11:51 pmPTY-CHS
8h 46m1 stop
Delta Logo
6:20 am - 12:50 pmCHS-PTY
7h 30m1 stop
$376Delta
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Thu, Sep 4 - Mon, Sep 8
American Airlines Logo
3:31 pm - 11:37 pmPTY-CHS
7h 06m1 stop
American Airlines Logo
7:28 pm - 12:55 pmCHS-PTY
18h 27m2 stops
$390American Airlines
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Thu, Sep 4 - Mon, Sep 8
United Airlines Logo
10:00 am - 4:44 pmPTY-CHS
29h 44m1 stop
United Airlines Logo
6:30 am - 6:38 pmCHS-PTY
13h 08m1 stop
$415United Airlines
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Fri, Oct 17 - Sat, Nov 1
American Airlines Logo
3:15 pm - 9:52 amPTY-CHS
17h 37m1 stop
American Airlines Logo
6:00 am - 2:00 pmCHS-PTY
9h 00m1 stop
$472American Airlines
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Fri, Oct 17 - Sat, Nov 1
American Airlines Logo
3:30 pm - 7:00 pmPTY-CHS
26h 30m1 stop
American Airlines Logo
10:56 am - 2:30 pmCHS-PTY
28h 34m1 stop
$475American Airlines
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Thu, Aug 28 - Mon, Sep 1
American Airlines Logo
3:15 pm - 3:40 pmPTY-CHS
23h 25m2 stops
American Airlines Logo
6:00 am - 2:00 pmCHS-PTY
9h 00m1 stop
$477American Airlines
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Fri, Oct 17 - Sat, Nov 1
American Airlines Logo
3:30 pm - 2:08 pmPTY-CHS
21h 38m2 stops
American Airlines Logo
10:56 am - 2:30 pmCHS-PTY
28h 34m1 stop
$525American Airlines
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Thu, Aug 28 - Mon, Sep 1
American Airlines Logo
3:15 pm - 10:49 amPTY-CHS
18h 34m2 stops
American Airlines Logo
6:00 am - 2:00 pmCHS-PTY
9h 00m2 stops
$584American Airlines
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Fri, Oct 17 - Sat, Nov 1
American Airlines Logo
3:30 pm - 2:08 pmPTY-CHS
21h 38m2 stops
American Airlines Logo
8:25 pm - 2:30 pmCHS-PTY
19h 05m2 stops
$627American Airlines
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Thu, Aug 28 - Mon, Sep 1
Logo
9:55 am - 9:05 amPTY-CHS
22h 10m3 stops
Logo
10:10 am - 9:10 pmCHS-PTY
12h 00m2 stops
$708
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Thu, Sep 4 - Mon, Sep 8

American Airlines flights from Panama City to Charleston

Our best American Airlines deals on Panama City to Charleston flight tickets
American Airlines
Sep 4
PTY3:31 pmPanama City Tocumen Intl
7h 06m
1 stop
CHS11:37 pmCharleston
Sep 8
CHS7:28 pmCharleston
18h 27m
2 stops
PTY12:55 pmPanama City Tocumen Intl
$390
Find similar
American Airlines
Oct 17
PTY3:15 pmPanama City Tocumen Intl
17h 37m
1 stop
CHS9:52 amCharleston
Nov 1
CHS6:00 amCharleston
9h 00m
1 stop
PTY2:00 pmPanama City Tocumen Intl
$472
Find similar
American Airlines
Aug 28
PTY3:30 pmPanama City Tocumen Intl
26h 30m
1 stop
CHS7:00 pmCharleston
Sep 1
CHS10:56 amCharleston
28h 34m
1 stop
PTY2:30 pmPanama City Tocumen Intl
$475
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 2, 2025.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 9/4

2:05 pm-11:51 pm

1 stop8h 46m

Charleston

Mon 9/8

6:20 am-12:50 pm

1 stop7h 30m

$376

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 9/4

3:31 pm-11:37 pm

1 stop7h 06m

Charleston

Mon 9/8

7:28 pm-12:55 pm

2 stops18h 27m

$390

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 10/17

10:00 am-4:44 pm

1 stop29h 44m

Charleston

Sat 11/1

6:30 am-6:38 pm

1 stop13h 08m

$415

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 10/17

3:15 pm-9:52 am

1 stop17h 37m

Charleston

Sat 11/1

6:00 am-2:00 pm

1 stop9h 00m

$472

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 8/28

3:30 pm-7:00 pm

1 stop26h 30m

Charleston

Mon 9/1

10:56 am-2:30 pm

1 stop28h 34m

$475

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 10/17

3:15 pm-3:40 pm

2 stops23h 25m

Charleston

Sat 11/1

6:00 am-2:00 pm

1 stop9h 00m

$477

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 8/28

3:30 pm-2:08 pm

2 stops21h 38m

Charleston

Mon 9/1

10:56 am-2:30 pm

1 stop28h 34m

$525

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 10/17

3:15 pm-10:49 am

2 stops18h 34m

Charleston

Sat 11/1

6:00 am-2:00 pm

2 stops9h 00m

$584

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 8/28

3:30 pm-2:08 pm

2 stops21h 38m

Charleston

Mon 9/1

8:25 pm-2:30 pm

2 stops19h 05m

$627

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 9/4

9:55 am-9:05 am

3 stops22h 10m

Charleston

Mon 9/8

10:10 am-9:10 pm

2 stops12h 00m

$708

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Charleston from

How to get the cheapest flight ticket from Panama City to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Panama City to Charleston is on a Wednesday. Travelers who choose to depart for Charleston on a Wednesday will often find tickets for as low as $502. The most expensive day to fly to Charleston is Sunday, with ticket prices averaging around $552.

What is the cheapest time of day to depart on your flight to Charleston?

The cheapest time of day to fly to Charleston is in the evening when flights can be purchased for as low as $469. In the afternoon is when there is more demand to fly to Charleston, so prices are often more expensive at around $554 per ticket.

When to book flights from Panama City to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Charleston according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Charleston (PTY to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Charleston

Best Price Found

$376

Fastest flight time

7h 06m

Direct flights

None

Airports in Charleston

1 airport
The best flight deal from Panama City to Charleston found on momondo in the last 72 hours is $376
The fastest flight from Panama City to Charleston takes 7h 06m
There are no direct flights from Panama City to Charleston. Popular non-direct route for this connection is Panama City Tocumen Intl Airport - Charleston Airport.
There is 1 airport near Charleston: Charleston (CHS)
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  • How far is Panama City Tocumen Intl to Charleston by plane?

    The distance between Panama City Tocumen Intl and Charleston is about 1643.0 mi. A reasonable flight in good conditions will take 7h 06m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Charleston Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Charleston Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Charleston Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Charleston Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The required travel and health documents for your Charleston Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Charleston Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Charleston?

Best airlines flying from Panama City to Charleston

Compare and see reviews for airlines that fly from Panama City to Charleston with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $423Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Kiawah Island
Mount Pleasant
Summerville
Edisto Island
Walterboro
Edisto Beach
Goose Creek
Santee
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Charleston?

It is quick and easy to find Panama City to Charleston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charleston that suits you.

Can I find flights from Panama City to Charleston with flexible booking policies on momondo?

momondo does allow users to show only those flights to Charleston from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Charleston?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama City to Charleston.

I’m not ready to book a flight from Panama City to Charleston right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Charleston flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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