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Cheap flights from Panama City to Charleston from $241

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Charleston departing on 3/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama City to Charleston

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
4:41 pm - 3:59 pm
PTY
-
CHS
23h 18m1 stop
United Airlines Logo
4:55 pm - 2:45 pm
CHS
-
PTY
21h 50m1 stop
$377United Airlines
Wed, Jan 21 - Wed, Jan 28
American Airlines Logo
2:27 pm - 9:48 am
PTY
-
CHS
19h 21m2 stops
American Airlines Logo
7:42 pm - 3:38 pm
CHS
-
PTY
19h 56m2 stops
$390American Airlines
Wed, Jan 21 - Wed, Jan 28
American Airlines Logo
4:50 pm - 8:47 am
PTY
-
CHS
15h 57m1 stop
American Airlines Logo
9:27 am - 3:38 pm
CHS
-
PTY
6h 11m1 stop
$429American Airlines
Sun, Jan 18 - Sun, Jan 25
American Airlines Logo
2:27 pm - 11:39 am
PTY
-
CHS
21h 12m2 stops
American Airlines Logo
6:10 am - 3:38 pm
CHS
-
PTY
9h 28m2 stops
$434American Airlines
Sun, Jan 18 - Sun, Jan 25
United Airlines Logo
4:41 pm - 9:57 pm
PTY
-
CHS
29h 16m1 stop
United Airlines Logo
6:30 am - 7:38 pm
CHS
-
PTY
13h 08m1 stop
$449United Airlines
Thu, Dec 18 - Wed, Dec 31
American Airlines Logo
4:55 pm - 10:37 am
PTY
-
CHS
17h 42m2 stops
American Airlines Logo
5:30 am - 3:54 pm
CHS
-
PTY
10h 24m1 stop
$463American Airlines
Thu, Dec 18 - Wed, Dec 31
American Airlines Logo
4:43 pm - 8:45 am
PTY
-
CHS
16h 02m1 stop
American Airlines Logo
8:08 pm - 3:54 pm
CHS
-
PTY
19h 46m2 stops
$484American Airlines
Mon, Dec 15 - Mon, Dec 29
American Airlines Logo
4:43 pm - 12:46 am
PTY
-
CHS
8h 03m1 stop
American Airlines Logo
8:07 pm - 1:53 pm
CHS
-
PTY
17h 46m1 stop
$487American Airlines
Mon, Dec 15 - Mon, Dec 29
American Airlines Logo
2:50 pm - 2:52 pm
PTY
-
CHS
24h 02m2 stops
American Airlines Logo
3:45 pm - 1:22 pm
CHS
-
PTY
21h 37m2 stops
$507American Airlines
Wed, Feb 18 - Sun, Feb 22
American Airlines Logo
4:55 pm - 8:47 am
PTY
-
CHS
15h 52m1 stop
American Airlines Logo
8:08 pm - 3:54 pm
CHS
-
PTY
19h 46m2 stops
$536American Airlines
Fri, Dec 26 - Mon, Dec 29

American Airlines flights from Panama City to Charleston

Our best American Airlines deals on Panama City to Charleston flight tickets
American Airlines
Jan 21
PTY2:27 pmPanama City Tocumen Intl
19h 21m
2 stops
CHS9:48 amCharleston
Jan 28
CHS7:42 pmCharleston
19h 56m
2 stops
PTY3:38 pmPanama City Tocumen Intl
$390
Find similar
American Airlines
Jan 18
PTY4:50 pmPanama City Tocumen Intl
15h 57m
1 stop
CHS8:47 amCharleston
Jan 25
CHS9:27 amCharleston
6h 11m
1 stop
PTY3:38 pmPanama City Tocumen Intl
$429
Find similar
American Airlines
Jan 18
PTY2:27 pmPanama City Tocumen Intl
21h 12m
2 stops
CHS11:39 amCharleston
Jan 25
CHS6:10 amCharleston
9h 28m
2 stops
PTY3:38 pmPanama City Tocumen Intl
$434
Find similar

United Airlines flights from Panama City to Charleston

Our best United Airlines deals on Panama City to Charleston flight tickets
United Airlines
Jan 21
PTY4:41 pmPanama City Tocumen Intl
23h 18m
1 stop
CHS3:59 pmCharleston
Jan 28
CHS4:55 pmCharleston
21h 50m
1 stop
PTY2:45 pmPanama City Tocumen Intl
$377
Find similar
United Airlines
Dec 18
PTY4:41 pmPanama City Tocumen Intl
29h 16m
1 stop
CHS9:57 pmCharleston
Dec 31
CHS6:30 amCharleston
13h 08m
1 stop
PTY7:38 pmPanama City Tocumen Intl
$449
Find similar
United Airlines
Dec 11
PTY11:35 amPanama City Tocumen Intl
28h 49m
1 stop
CHS4:24 pmCharleston
Dec 18
CHS6:30 amCharleston
13h 08m
1 stop
PTY7:38 pmPanama City Tocumen Intl
$654
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 1/21

4:41 pm-3:59 pm

1 stop23h 18m

Charleston

Wed 1/28

4:55 pm-2:45 pm

1 stop21h 50m

$377

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 1/21

2:27 pm-9:48 am

2 stops19h 21m

Charleston

Wed 1/28

7:42 pm-3:38 pm

2 stops19h 56m

$390

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 1/18

4:50 pm-8:47 am

1 stop15h 57m

Charleston

Sun 1/25

9:27 am-3:38 pm

1 stop6h 11m

$429

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 1/18

2:27 pm-11:39 am

2 stops21h 12m

Charleston

Sun 1/25

6:10 am-3:38 pm

2 stops9h 28m

$434

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 12/18

4:41 pm-9:57 pm

1 stop29h 16m

Charleston

Wed 12/31

6:30 am-7:38 pm

1 stop13h 08m

$449

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 12/18

4:55 pm-10:37 am

2 stops17h 42m

Charleston

Wed 12/31

5:30 am-3:54 pm

1 stop10h 24m

$463

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 12/15

4:43 pm-8:45 am

1 stop16h 02m

Charleston

Mon 12/29

8:08 pm-3:54 pm

2 stops19h 46m

$484

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 12/15

4:43 pm-12:46 am

1 stop8h 03m

Charleston

Mon 12/29

8:07 pm-1:53 pm

1 stop17h 46m

$487

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 2/18

2:50 pm-2:52 pm

2 stops24h 02m

Charleston

Sun 2/22

3:45 pm-1:22 pm

2 stops21h 37m

$507

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 12/26

4:55 pm-8:47 am

1 stop15h 52m

Charleston

Mon 12/29

8:08 pm-3:54 pm

2 stops19h 46m

$536

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Charleston from

How to get the cheapest flight ticket from Panama City to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Panama City to Charleston is on a Wednesday. Travelers who choose to depart for Charleston on a Wednesday will often find tickets for as low as $502. The most expensive day to fly to Charleston is Sunday, with ticket prices averaging around $552.

What is the cheapest time of day to depart on your flight to Charleston?

The cheapest time of day to fly to Charleston is in the evening when flights can be purchased for as low as $469. In the afternoon is when there is more demand to fly to Charleston, so prices are often more expensive at around $554 per ticket.

When to book flights from Panama City to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Charleston according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Charleston (PTY to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Charleston

Fastest flight time

8h 36m

Direct flights

None
The fastest flight from Panama City to Charleston takes 8h 36m
There are no direct flights from Panama City to Charleston. There are no popular flight routes from Panama City to Charleston.
Search flight deals

  • How far is Panama City Tocumen Intl to Charleston by plane?

    The distance between Panama City Tocumen Intl and Charleston is about 1643.0 mi. A reasonable flight in good conditions will take 7h 50m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Charleston Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Charleston Airport refresh daily.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Charleston Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The required travel and health documents for your Charleston Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Charleston Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Kiawah Island
Summerville
Mount Pleasant
Edisto Island
Santee
Walterboro
Goose Creek
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Charleston?

It is quick and easy to find Panama City to Charleston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charleston that suits you.

Can I find flights from Panama City to Charleston with flexible booking policies on momondo?

momondo does allow users to show only those flights to Charleston from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Charleston?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama City to Charleston.

I’m not ready to book a flight from Panama City to Charleston right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Charleston flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Charleston trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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