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Cheap flights from Panama City to Charleston from $517

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Charleston departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City to Charleston

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
2:15 pm - 10:56 pm
PTY
-
CHS
7h 41m
1 stop
Delta Logo
5:15 am - 12:50 pm
CHS
-
PTY
8h 35m
1 stop
$517Delta
Wed, May 27 - Wed, Jun 3
United Airlines Logo
10:00 am - 10:23 am
PTY
-
CHS
23h 23m
2 stops
United Airlines Logo
10:00 am - 7:31 pm
CHS
-
PTY
10h 31m
2 stops
$530United Airlines
Wed, May 27 - Wed, Jun 3
United Airlines Logo
9:45 am - 10:16 am
PTY
-
CHS
23h 31m
2 stops
United Airlines Logo
7:47 pm - 7:31 pm
CHS
-
PTY
24h 44m
2 stops
$536United Airlines
Fri, Jun 5 - Mon, Jun 15
American Airlines Logo
1:14 pm - 12:08 pm
PTY
-
CHS
21h 54m
2 stops
American Airlines Logo
3:12 pm - 12:13 pm
CHS
-
PTY
22h 01m
2 stops
$559American Airlines
Mon, Jun 1 - Tue, Jun 16
American Airlines Logo
1:14 pm - 1:26 pm
PTY
-
CHS
23h 12m
2 stops
American Airlines Logo
12:58 pm - 12:13 pm
CHS
-
PTY
24h 15m
2 stops
$560American Airlines
Mon, Jun 1 - Tue, Jun 16
American Airlines Logo
1:14 pm - 12:08 pm
PTY
-
CHS
21h 54m
2 stops
American Airlines Logo
3:12 pm - 12:13 pm
CHS
-
PTY
22h 01m
2 stops
$561American Airlines
Mon, Jun 1 - Tue, Jun 16
Delta Logo
2:15 pm - 11:59 pm
PTY
-
CHS
8h 44m
1 stop
Delta Logo
5:15 am - 12:50 pm
CHS
-
PTY
8h 35m
1 stop
$566Delta
Wed, May 27 - Wed, Jun 3
United Airlines Logo
3:30 pm - 10:08 am
PTY
-
CHS
17h 38m
2 stops
United Airlines Logo
7:47 pm - 7:31 pm
CHS
-
PTY
24h 44m
2 stops
$573United Airlines
Mon, Jun 1 - Tue, Jun 16
American Airlines Logo
1:14 pm - 11:31 am
PTY
-
CHS
21h 17m
2 stops
American Airlines Logo
4:13 pm - 12:13 pm
CHS
-
PTY
21h 00m
2 stops
$574American Airlines
Wed, May 27 - Wed, Jun 3
American Airlines Logo
1:14 pm - 11:31 am
PTY
-
CHS
21h 17m
2 stops
American Airlines Logo
6:42 pm - 12:13 pm
CHS
-
PTY
18h 31m
2 stops
$587American Airlines
Wed, May 27 - Wed, Jun 3

American Airlines flights from Panama City to Charleston

Our best American Airlines deals on Panama City to Charleston flight tickets
American Airlines
Jun 1
PTY1:14 pmPanama City Tocumen Intl
21h 54m
2 stops
CHS12:08 pmCharleston
Jun 16
CHS3:12 pmCharleston
22h 01m
2 stops
PTY12:13 pmPanama City Tocumen Intl
$559
American Airlines
Jun 1
PTY1:14 pmPanama City Tocumen Intl
23h 12m
2 stops
CHS1:26 pmCharleston
Jun 16
CHS12:58 pmCharleston
24h 15m
2 stops
PTY12:13 pmPanama City Tocumen Intl
$560
American Airlines
Jun 1
PTY1:14 pmPanama City Tocumen Intl
21h 54m
2 stops
CHS12:08 pmCharleston
Jun 16
CHS3:12 pmCharleston
22h 01m
2 stops
PTY12:13 pmPanama City Tocumen Intl
$561

JetBlue flights from Panama City to Charleston

Our best JetBlue deals on Panama City to Charleston flight tickets
JetBlue
Jun 1
PTY2:15 pmPanama City Tocumen Intl
18h 23m
1 stop
CHS9:38 amCharleston
Jun 16
CHS5:10 amCharleston
8h 59m
1 stop
PTY1:09 pmPanama City Tocumen Intl
$646
JetBlue
Jun 5
PTY2:15 pmPanama City Tocumen Intl
18h 23m
1 stop
CHS9:38 amCharleston
Jun 15
CHS5:10 amCharleston
8h 59m
1 stop
PTY1:09 pmPanama City Tocumen Intl
$666

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

2:15 pm-10:56 pm

1 stop7h 41m

Charleston

Wed 6/3

5:15 am-12:50 pm

1 stop8h 35m

$517

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

10:00 am-10:23 am

2 stops23h 23m

Charleston

Wed 6/3

10:00 am-7:31 pm

2 stops10h 31m

$530

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 6/5

9:45 am-10:16 am

2 stops23h 31m

Charleston

Mon 6/15

7:47 pm-7:31 pm

2 stops24h 44m

$536

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

1:14 pm-12:08 pm

2 stops21h 54m

Charleston

Tue 6/16

3:12 pm-12:13 pm

2 stops22h 01m

$559

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

1:14 pm-1:26 pm

2 stops23h 12m

Charleston

Tue 6/16

12:58 pm-12:13 pm

2 stops24h 15m

$560

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

1:14 pm-12:08 pm

2 stops21h 54m

Charleston

Tue 6/16

3:12 pm-12:13 pm

2 stops22h 01m

$561

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

2:15 pm-11:59 pm

1 stop8h 44m

Charleston

Wed 6/3

5:15 am-12:50 pm

1 stop8h 35m

$566

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

3:30 pm-10:08 am

2 stops17h 38m

Charleston

Tue 6/16

7:47 pm-7:31 pm

2 stops24h 44m

$573

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

1:14 pm-11:31 am

2 stops21h 17m

Charleston

Wed 6/3

4:13 pm-12:13 pm

2 stops21h 00m

$574

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

1:14 pm-11:31 am

2 stops21h 17m

Charleston

Wed 6/3

6:42 pm-12:13 pm

2 stops18h 31m

$587

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Charleston from

How to get the cheapest flight ticket from Panama City to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Charleston?

What is the cheapest month to fly to Charleston?

The cheapest month to fly to Charleston from Panama City is in December. Flight prices, which tend to average around $376, are often lower during this time because this is during the off-season. The month of February is another great option to travel to Charleston, with average flight prices from Panama City averaging around $435.

When to book flights from Panama City to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Charleston according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Charleston (PTY to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Charleston

Fastest flight time

7h 41m

Direct flights

None
The fastest flight from Panama City to Charleston takes 7h 41m
There are no direct flights from Panama City to Charleston. There are no popular flight routes from Panama City to Charleston.
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Frequently asked questions about flying from Panama City to Charleston

  • How far is Panama City Tocumen Intl to Charleston by plane?

    The distance between Panama City Tocumen Intl and Charleston is about 1643.0 mi. A reasonable flight in good conditions will take 7h 41m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Charleston Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Charleston Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Charleston Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Charleston Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The required travel and health documents for your Charleston Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Charleston Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Charleston?

Best airlines flying from Panama City to Charleston

Compare and see reviews for airlines that fly from Panama City to Charleston with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $397Free CancellationRating
7.1
11,670 reviews
Search American Airlines flights

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
Summerville
Kiawah Island
North Charleston
Mount Pleasant
Edisto Island
Santee
Walterboro
Goose Creek
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Charleston?

It is quick and easy to find Panama City to Charleston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charleston that suits you.

Can I find flights from Panama City to Charleston with flexible booking policies on momondo?

momondo does allow users to show only those flights to Charleston from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Charleston?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama City to Charleston.

I’m not ready to book a flight from Panama City to Charleston right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Charleston flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Charleston trip

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