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Cheap flights from Panama City to Charleston from $271

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Charleston departing on 9/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama City to Charleston

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:49 pm - 12:24 am
PTY
-
CHS
9h 35m
1 stop
American Airlines Logo
4:46 pm - 12:46 pm
CHS
-
PTY
21h 00m
2 stops
$494American Airlines
Wed, May 6 - Wed, May 13
United Airlines Logo
3:30 pm - 10:08 am
PTY
-
CHS
17h 38m
2 stops
United Airlines Logo
6:30 pm - 2:14 pm
CHS
-
PTY
20h 44m
2 stops
$495United Airlines
Mon, Jun 1 - Tue, Jun 16
American Airlines Logo
1:14 pm - 11:59 pm
PTY
-
CHS
9h 45m
1 stop
American Airlines Logo
7:34 pm - 12:13 pm
CHS
-
PTY
17h 39m
1 stop
$498American Airlines
Wed, May 27 - Wed, Jun 3
United Airlines Logo
10:00 am - 10:15 pm
PTY
-
CHS
11h 15m
1 stop
United Airlines Logo
11:18 am - 7:31 pm
CHS
-
PTY
9h 13m
1 stop
$504United Airlines
Wed, May 27 - Wed, Jun 3
United Airlines Logo
10:00 am - 10:08 am
PTY
-
CHS
23h 08m
2 stops
United Airlines Logo
6:30 pm - 4:12 pm
CHS
-
PTY
22h 42m
2 stops
$509United Airlines
Wed, May 27 - Wed, Jun 3
American Airlines Logo
1:14 pm - 11:31 am
PTY
-
CHS
21h 17m
2 stops
American Airlines Logo
12:58 pm - 12:13 pm
CHS
-
PTY
24h 15m
2 stops
$512American Airlines
Wed, May 27 - Wed, Jun 3
United Airlines Logo
10:00 am - 10:15 pm
PTY
-
CHS
11h 15m
1 stop
United Airlines Logo
10:00 am - 7:31 pm
CHS
-
PTY
10h 31m
2 stops
$515United Airlines
Fri, Jun 5 - Mon, Jun 15
United Airlines Logo
10:55 pm - 9:10 am
PTY
-
CHS
9h 15m
1 stop
United Airlines Logo
6:35 am - 6:37 pm
CHS
-
PTY
13h 02m
1 stop
$524United Airlines
Sun, May 10 - Thu, May 14
United Airlines Logo
3:30 pm - 12:17 pm
PTY
-
CHS
19h 47m
2 stops
United Airlines Logo
11:15 am - 7:31 pm
CHS
-
PTY
9h 16m
1 stop
$528United Airlines
Sun, May 10 - Thu, May 14
United Airlines Logo
3:30 pm - 10:08 am
PTY
-
CHS
17h 38m
2 stops
United Airlines Logo
6:30 pm - 4:12 pm
CHS
-
PTY
22h 42m
2 stops
$531United Airlines
Mon, Jun 1 - Tue, Jun 16

American Airlines flights from Panama City to Charleston

Our best American Airlines deals on Panama City to Charleston flight tickets
American Airlines
May 6
PTY1:49 pmPanama City Tocumen Intl
9h 35m
1 stop
CHS12:24 amCharleston
May 13
CHS4:46 pmCharleston
21h 00m
2 stops
PTY12:46 pmPanama City Tocumen Intl
$494
American Airlines
May 27
PTY1:14 pmPanama City Tocumen Intl
9h 45m
1 stop
CHS11:59 pmCharleston
Jun 3
CHS7:34 pmCharleston
17h 39m
1 stop
PTY12:13 pmPanama City Tocumen Intl
$498
American Airlines
May 27
PTY1:14 pmPanama City Tocumen Intl
21h 17m
2 stops
CHS11:31 amCharleston
Jun 3
CHS12:58 pmCharleston
24h 15m
2 stops
PTY12:13 pmPanama City Tocumen Intl
$512

United Airlines flights from Panama City to Charleston

Our best United Airlines deals on Panama City to Charleston flight tickets
United Airlines
Jun 1
PTY3:30 pmPanama City Tocumen Intl
17h 38m
2 stops
CHS10:08 amCharleston
Jun 16
CHS6:30 pmCharleston
20h 44m
2 stops
PTY2:14 pmPanama City Tocumen Intl
$495
United Airlines
May 27
PTY10:00 amPanama City Tocumen Intl
11h 15m
1 stop
CHS10:15 pmCharleston
Jun 3
CHS11:18 amCharleston
9h 13m
1 stop
PTY7:31 pmPanama City Tocumen Intl
$504
United Airlines
May 27
PTY10:00 amPanama City Tocumen Intl
23h 08m
2 stops
CHS10:08 amCharleston
Jun 3
CHS6:30 pmCharleston
22h 42m
2 stops
PTY4:12 pmPanama City Tocumen Intl
$509

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/6

1:49 pm-12:24 am

1 stop9h 35m

Charleston

Wed 5/13

4:46 pm-12:46 pm

2 stops21h 00m

$494

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

3:30 pm-10:08 am

2 stops17h 38m

Charleston

Tue 6/16

6:30 pm-2:14 pm

2 stops20h 44m

$495

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

1:14 pm-11:59 pm

1 stop9h 45m

Charleston

Wed 6/3

7:34 pm-12:13 pm

1 stop17h 39m

$498
Quickest round-trip

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

10:00 am-10:15 pm

1 stop11h 15m

Charleston

Wed 6/3

11:18 am-7:31 pm

1 stop9h 13m

$504

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

10:00 am-10:08 am

2 stops23h 08m

Charleston

Wed 6/3

6:30 pm-4:12 pm

2 stops22h 42m

$509

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

1:14 pm-11:31 am

2 stops21h 17m

Charleston

Wed 6/3

12:58 pm-12:13 pm

2 stops24h 15m

$512

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 6/5

10:00 am-10:15 pm

1 stop11h 15m

Charleston

Mon 6/15

10:00 am-7:31 pm

2 stops10h 31m

$515

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 5/10

10:55 pm-9:10 am

1 stop9h 15m

Charleston

Thu 5/14

6:35 am-6:37 pm

1 stop13h 02m

$524

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 5/10

3:30 pm-12:17 pm

2 stops19h 47m

Charleston

Thu 5/14

11:15 am-7:31 pm

1 stop9h 16m

$528

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

3:30 pm-10:08 am

2 stops17h 38m

Charleston

Tue 6/16

6:30 pm-4:12 pm

2 stops22h 42m

$531

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Charleston from

How to get the cheapest flight ticket from Panama City to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Charleston?

The cheapest month to fly to Charleston from Panama City is in December. Flight prices, which tend to average around $376, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Charleston, with average flight prices from Panama City averaging around $395.

When to book flights from Panama City to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Charleston according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Charleston (PTY to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Charleston

Fastest flight time

11h 15m

Direct flights

None
The fastest flight from Panama City to Charleston takes 11h 15m
There are no direct flights from Panama City to Charleston. There are no popular flight routes from Panama City to Charleston.
Search flight deals

  • How far is Panama City Tocumen Intl to Charleston by plane?

    The distance between Panama City Tocumen Intl and Charleston is about 1643.0 mi. A reasonable flight in good conditions will take 11h 15m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Charleston Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Charleston Airport refresh daily.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Charleston Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The required travel and health documents for your Charleston Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Charleston Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Summerville
Kiawah Island
Mount Pleasant
Edisto Island
Santee
Walterboro
Goose Creek
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Charleston?

It is quick and easy to find Panama City to Charleston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charleston that suits you.

Can I find flights from Panama City to Charleston with flexible booking policies on momondo?

momondo does allow users to show only those flights to Charleston from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Charleston?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama City to Charleston.

I’m not ready to book a flight from Panama City to Charleston right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Charleston flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Charleston trip

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