Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Panama City to Cleveland from $304

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cleveland departing on 4/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama City to Cleveland

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
3:30 pm - 11:25 am
PTY
-
CLE
18h 55m
1 stop
United Airlines Logo
2:54 pm - 4:12 pm
CLE
-
PTY
26h 18m
1 stop
$581United Airlines
Mon, Apr 6 - Mon, Apr 13
Multiple Airlines Logo
12:03 pm - 11:28 pm
PTY
-
CLE
10h 25m
1 stop
Multiple Airlines Logo
4:55 pm - 1:00 am
CLE
-
PTY
33h 05m
2 stops
$596Multiple Airlines
Tue, Mar 17 - Mon, Mar 23
Multiple Airlines Logo
9:33 pm - 10:36 am
PTY
-
CLE
12h 03m
2 stops
Multiple Airlines Logo
4:38 pm - 8:06 am
CLE
-
PTY
16h 28m
1 stop
$598Multiple Airlines
Mon, Apr 6 - Mon, Apr 13
United Airlines Logo
3:41 pm - 11:26 am
PTY
-
CLE
18h 45m
1 stop
United Airlines Logo
6:00 am - 6:37 pm
CLE
-
PTY
13h 37m
1 stop
$602United Airlines
Wed, Mar 25 - Wed, Apr 1
American Airlines Logo
1:40 pm - 11:58 pm
PTY
-
CLE
9h 18m
1 stop
American Airlines Logo
7:18 pm - 3:01 pm
CLE
-
PTY
20h 43m
2 stops
$616American Airlines
Wed, Mar 25 - Wed, Apr 1
United Airlines Logo
3:41 pm - 11:26 am
PTY
-
CLE
18h 45m
1 stop
United Airlines Logo
6:09 pm - 4:07 pm
CLE
-
PTY
22h 58m
1 stop
$624United Airlines
Tue, Mar 17 - Mon, Mar 23
American Airlines Logo
3:10 pm - 11:52 am
PTY
-
CLE
19h 42m
2 stops
American Airlines Logo
6:55 pm - 12:40 pm
CLE
-
PTY
18h 45m
2 stops
$650American Airlines
Tue, Mar 17 - Mon, Mar 23
American Airlines Logo
3:51 pm - 1:01 pm
PTY
-
CLE
20h 10m
2 stops
American Airlines Logo
7:15 pm - 12:46 pm
CLE
-
PTY
18h 31m
2 stops
$669American Airlines
Mon, Apr 6 - Mon, Apr 13
Multiple Airlines Logo
9:45 am - 5:13 pm
PTY
-
CLE
30h 28m
3 stops
Multiple Airlines Logo
6:31 pm - 4:55 pm
CLE
-
PTY
23h 24m
3 stops
$746Multiple Airlines
Tue, Mar 17 - Mon, Mar 23
Multiple Airlines Logo
2:55 pm - 5:13 pm
PTY
-
CLE
25h 18m
3 stops
Multiple Airlines Logo
6:31 pm - 5:00 pm
CLE
-
PTY
23h 29m
3 stops
$906Multiple Airlines
Wed, Mar 25 - Wed, Apr 1

American Airlines flights from Panama City to Cleveland

Our best American Airlines deals on Panama City to Cleveland flight tickets
American Airlines
Mar 25
PTY1:40 pmPanama City Tocumen Intl
9h 18m
1 stop
CLE11:58 pmCleveland Hopkins Intl
Apr 1
CLE7:18 pmCleveland Hopkins Intl
20h 43m
2 stops
PTY3:01 pmPanama City Tocumen Intl
$616
American Airlines
Mar 17
PTY3:10 pmPanama City Tocumen Intl
19h 42m
2 stops
CLE11:52 amCleveland Hopkins Intl
Mar 23
CLE6:55 pmCleveland Hopkins Intl
18h 45m
2 stops
PTY12:40 pmPanama City Tocumen Intl
$650
American Airlines
Apr 6
PTY3:51 pmPanama City Tocumen Intl
20h 10m
2 stops
CLE1:01 pmCleveland Hopkins Intl
Apr 13
CLE7:15 pmCleveland Hopkins Intl
18h 31m
2 stops
PTY12:46 pmPanama City Tocumen Intl
$669

United Airlines flights from Panama City to Cleveland

Our best United Airlines deals on Panama City to Cleveland flight tickets
United Airlines
Apr 6
PTY3:30 pmPanama City Tocumen Intl
18h 55m
1 stop
CLE11:25 amCleveland Hopkins Intl
Apr 13
CLE2:54 pmCleveland Hopkins Intl
26h 18m
1 stop
PTY4:12 pmPanama City Tocumen Intl
$581
United Airlines
Mar 25
PTY3:41 pmPanama City Tocumen Intl
18h 45m
1 stop
CLE11:26 amCleveland Hopkins Intl
Apr 1
CLE6:00 amCleveland Hopkins Intl
13h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$602
United Airlines
Mar 17
PTY3:41 pmPanama City Tocumen Intl
18h 45m
1 stop
CLE11:26 amCleveland Hopkins Intl
Mar 23
CLE6:09 pmCleveland Hopkins Intl
22h 58m
1 stop
PTY4:07 pmPanama City Tocumen Intl
$624

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Panama City to Cleveland that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 4/6

3:30 pm-11:25 am

1 stop18h 55m

Cleveland Hopkins Intl

Mon 4/13

2:54 pm-4:12 pm

1 stop26h 18m

$581

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Tue 3/17

12:03 pm-11:28 pm

1 stop10h 25m

Cleveland Hopkins Intl

Mon 3/23

4:55 pm-1:00 am

2 stops33h 05m

$596

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 4/6

9:33 pm-10:36 am

2 stops12h 03m

Cleveland Hopkins Intl

Mon 4/13

4:38 pm-8:06 am

1 stop16h 28m

$598

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Wed 3/25

3:41 pm-11:26 am

1 stop18h 45m

Cleveland Hopkins Intl

Wed 4/1

6:00 am-6:37 pm

1 stop13h 37m

$602

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Wed 3/25

1:40 pm-11:58 pm

1 stop9h 18m

Cleveland Hopkins Intl

Wed 4/1

7:18 pm-3:01 pm

2 stops20h 43m

$616

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Tue 3/17

3:41 pm-11:26 am

1 stop18h 45m

Cleveland Hopkins Intl

Mon 3/23

6:09 pm-4:07 pm

1 stop22h 58m

$624

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Tue 3/17

3:10 pm-11:52 am

2 stops19h 42m

Cleveland Hopkins Intl

Mon 3/23

6:55 pm-12:40 pm

2 stops18h 45m

$650

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 4/6

3:51 pm-1:01 pm

2 stops20h 10m

Cleveland Hopkins Intl

Mon 4/13

7:15 pm-12:46 pm

2 stops18h 31m

$669

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Tue 3/17

9:45 am-5:13 pm

3 stops30h 28m

Cleveland Hopkins Intl

Mon 3/23

6:31 pm-4:55 pm

3 stops23h 24m

$746

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Wed 3/25

2:55 pm-5:13 pm

3 stops25h 18m

Cleveland Hopkins Intl

Wed 4/1

6:31 pm-5:00 pm

3 stops23h 29m

$906

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Cleveland from

How to get the cheapest flight ticket from Panama City to Cleveland

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cleveland?

In general, November is the cheapest month to fly from Panama City to Cleveland. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $504. If you’re not able to fly to Cleveland in November, then February is your next best option. Flight prices from Panama City to Cleveland during February average around $526.

When to book flights from Panama City to Cleveland

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cleveland according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cleveland (PTY to CLE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cleveland

Fastest flight time

18h 55m

Direct flights

None
The fastest flight from Panama City to Cleveland takes 18h 55m
There are no direct flights from Panama City to Cleveland. There are no popular flight routes from Panama City to Cleveland.
Search flight deals

  • How far is Panama City Tocumen Intl to Cleveland Hopkins Intl by plane?

    The distance between Panama City Tocumen Intl and Cleveland Hopkins Intl is about 2248.9 mi. By plane, this route typically takes 18h 55m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cleveland Hopkins Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cleveland Hopkins Intl Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cleveland Hopkins Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cleveland Hopkins Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cleveland Hopkins Intl Airport.

  • What documentation or ID do you need to fly to Cleveland Hopkins Intl Airport?

    The required travel and health documents for your Cleveland Hopkins Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cleveland Hopkins Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Cleveland?

Best airlines flying from Panama City to Cleveland

Compare and see reviews for airlines that fly from Panama City to Cleveland with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $613Free CancellationRating
7.4
9,344 reviews
Search United Airlines flights

Traveling to a place near Cleveland?

Book flights to Cleveland if you plan to visit one of these locations
Sandusky
Mansfield
Beachwood
Independence
Elyria
Mentor
Geneva-on-the-Lake
Westlake
Kent
Wooster
Streetsboro
North Olmsted
Cuyahoga Falls
Painesville
Willoughby
Ashland
Medina
Lakewood
Avon
Kelleys Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cleveland?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Cleveland from Panama City.

Can I find flights from Panama City to Cleveland with flexible booking policies on momondo?

All flight searches from Panama City to Cleveland on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Cleveland?

Once all potential Panama City to Cleveland flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Cleveland right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Panama City to Cleveland now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Cleveland and let you know when they change.

An easier way to manage your Cleveland trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 3/25
Wed 4/1
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States