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Cheap flights from Panama City to Cleveland from $287

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cleveland departing on 12/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
9:40 am - 7:53 pmPTY-CLE
9h 13m1 stop
Copa Airlines Logo
7:13 am - 5:53 pmCLE-PTY
11h 40m1 stop
$844Copa Airlines
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Tue, Mar 10 - Wed, Mar 11

Copa Airlines flights from Panama City to Cleveland

Our best Copa Airlines deals on Panama City to Cleveland flight tickets
Copa Airlines
Nov 9
PTY6:41 pmPanama City Tocumen Intl
15h 00m
1 stop
CLE9:41 amCleveland Hopkins Intl
Nov 10
CLE7:50 pmCleveland Hopkins Intl
17h 41m
1 stop
PTY1:31 pmPanama City Tocumen Intl
$741
Find similar
Copa Airlines
Mar 10
PTY9:40 amPanama City Tocumen Intl
9h 13m
1 stop
CLE7:53 pmCleveland Hopkins Intl
Mar 11
CLE7:13 amCleveland Hopkins Intl
11h 40m
1 stop
PTY5:53 pmPanama City Tocumen Intl
$844
Find similar

American Airlines flights from Panama City to Cleveland

Our best American Airlines deals on Panama City to Cleveland flight tickets
American Airlines
Nov 8
PTY2:49 pmPanama City Tocumen Intl
18h 23m
2 stops
CLE9:12 amCleveland Hopkins Intl
Nov 10
CLE4:34 pmCleveland Hopkins Intl
21h 15m
2 stops
PTY1:49 pmPanama City Tocumen Intl
$767
Find similar
American Airlines
Nov 8
PTY2:49 pmPanama City Tocumen Intl
9h 04m
1 stop
CLE11:53 pmCleveland Hopkins Intl
Nov 10
CLE6:06 amCleveland Hopkins Intl
7h 43m
1 stop
PTY1:49 pmPanama City Tocumen Intl
$809
Find similar
American Airlines
Nov 8
PTY2:49 pmPanama City Tocumen Intl
21h 31m
2 stops
CLE12:20 pmCleveland Hopkins Intl
Nov 11
CLE5:39 pmCleveland Hopkins Intl
20h 10m
2 stops
PTY1:49 pmPanama City Tocumen Intl
$826
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Panama City to Cleveland that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Tue 3/10

9:40 am-7:53 pm

1 stop9h 13m

Cleveland Hopkins Intl

Wed 3/11

7:13 am-5:53 pm

1 stop11h 40m

$844

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Wed 12/3

5:50 pm-11:56 pm

2 stops30h 06m

$287

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Wed 12/3

3:46 pm-12:37 am

1 stop8h 51m

$307

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 12/5

2:50 pm-11:56 pm

1 stop9h 06m

$311

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Wed 12/3

5:50 pm-3:48 pm

3 stops21h 58m

$312

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 12/5

4:43 pm-1:34 pm

2 stops20h 51m

$316

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sat 12/6

8:55 am-11:08 am

1 stop26h 13m

$328

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Tue 12/2

2:55 am-10:46 pm

2 stops19h 51m

$329

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 11/10

4:41 pm-11:04 am

1 stop18h 23m

$340

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 12/5

2:55 am-6:57 pm

2 stops16h 02m

$727

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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See travel insights to Cleveland from

How to get the cheapest flight ticket from Panama City to Cleveland

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Cleveland?

What is the cheapest month to fly to Cleveland?

In general, January is the cheapest month to fly from Panama City to Cleveland. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $489. If you’re not able to fly to Cleveland in January, then September is your next best option. Flight prices from Panama City to Cleveland during September average around $526.

What is the cheapest day to depart on your flight to Cleveland?

The cheapest day to depart from Panama City to Cleveland is on a Wednesday when prices can be found for as low as $504. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Cleveland on Friday is $680.

What is the cheapest time of day to depart on your flight to Cleveland?

Our data shows that the cheapest Panama City to Cleveland flights are usually those with departure times in the afternoon. Our users have found flights to Cleveland in the afternoon for as low as $517. In contrast, the most expensive time of day to depart to Cleveland is in the morning when prices are around $586.

When to book flights from Panama City to Cleveland

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cleveland according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cleveland (PTY to CLE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cleveland

Direct flights

None
There are no direct flights from Panama City to Cleveland. There are no popular flight routes from Panama City to Cleveland.
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  • How far is Panama City Tocumen Intl to Cleveland Hopkins Intl by plane?

    The distance between Panama City Tocumen Intl and Cleveland Hopkins Intl is about 2248.9 mi. By plane, this route typically takes 9h 13m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cleveland Hopkins Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cleveland Hopkins Intl Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cleveland Hopkins Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cleveland Hopkins Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cleveland Hopkins Intl Airport.

  • What documentation or ID do you need to fly to Cleveland Hopkins Intl Airport?

    The required travel and health documents for your Cleveland Hopkins Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cleveland Hopkins Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Cleveland?

Best airlines flying from Panama City to Cleveland

Compare and see reviews for airlines that fly from Panama City to Cleveland with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $483Free CancellationRating
7.9
8,002 reviews
Search Delta flights
United AirlinesPriceFrom $580Free CancellationRating
7.4
8,997 reviews
Search United Airlines flights

Traveling to a place near Cleveland?

Book flights to Cleveland if you plan to visit one of these locations
Sandusky
Beachwood
Mansfield
Elyria
Geneva-on-the-Lake
Mentor
Independence
Wooster
Kent
Westlake
North Olmsted
Streetsboro
Willoughby
Ashland
Cuyahoga Falls
Medina
Painesville
Lakewood
Kelleys Island
Avon

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cleveland?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Cleveland from Panama City.

Can I find flights from Panama City to Cleveland with flexible booking policies on momondo?

All flight searches from Panama City to Cleveland on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Cleveland?

Once all potential Panama City to Cleveland flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Cleveland right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Panama City to Cleveland now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Cleveland and let you know when they change.

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