Cheap flights from Panama City to Cali from $130

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cali departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

Find the cheapest flights from Panama City to Cali

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
12:29 pm - 2:10 pm
PTY
-
CLO
1h 41mnonstop
Copa Airlines Logo
5:03 am - 6:34 am
CLO
-
PTY
1h 31mnonstop
$244Copa Airlines
Fri, Feb 20 - Tue, Feb 24
Avianca Logo
9:45 am - 2:45 pm
PTY
-
CLO
5h 00m
1 stop
Avianca Logo
8:15 pm - 1:00 am
CLO
-
PTY
4h 45m
1 stop
$250Avianca
Fri, Mar 6 - Tue, Mar 10
Avianca Logo
5:50 pm - 10:35 pm
PTY
-
CLO
4h 45m
1 stop
Avianca Logo
9:50 am - 2:00 pm
CLO
-
PTY
4h 10m
1 stop
$251Avianca
Mon, Feb 16 - Fri, Feb 20
Avianca Logo
2:55 am - 9:30 am
PTY
-
CLO
6h 35m
1 stop
Avianca Logo
11:50 am - 4:55 pm
CLO
-
PTY
5h 05m
1 stop
$276Avianca
Fri, Feb 27 - Fri, Mar 13
Copa Airlines Logo
9:25 am - 11:04 am
PTY
-
CLO
1h 39mnonstop
Copa Airlines Logo
5:03 am - 6:34 am
CLO
-
PTY
1h 31mnonstop
$286Copa Airlines
Sun, Mar 1 - Sun, Mar 29
Copa Airlines Logo
9:25 am - 11:06 am
PTY
-
CLO
1h 41mnonstop
Copa Airlines Logo
3:10 pm - 4:44 pm
CLO
-
PTY
1h 34mnonstop
$287Copa Airlines
Wed, Apr 15 - Fri, May 15
Avianca Logo
2:55 pm - 7:30 pm
PTY
-
CLO
4h 35m
1 stop
Avianca Logo
6:45 pm - 1:00 am
CLO
-
PTY
6h 15m
1 stop
$302Avianca
Tue, Mar 17 - Sun, Mar 22
Multiple Airlines Logo
9:45 am - 10:03 pm
PTY
-
CLO
12h 18m
1 stop
Multiple Airlines Logo
10:51 pm - 4:55 pm
CLO
-
PTY
18h 04m
2 stops
$323Multiple Airlines
Tue, Mar 17 - Sun, Mar 22
Multiple Airlines Logo
9:45 am - 2:45 pm
PTY
-
CLO
5h 00m
1 stop
Multiple Airlines Logo
3:11 pm - 4:44 pm
CLO
-
PTY
1h 33mnonstop
$324Multiple Airlines
Fri, Mar 6 - Thu, Mar 12
Multiple Airlines Logo
2:55 am - 7:10 am
PTY
-
CLO
4h 15m
1 stop
Multiple Airlines Logo
8:48 am - 10:20 am
CLO
-
PTY
1h 32mnonstop
$325Multiple Airlines
Thu, Mar 5 - Fri, Mar 13

Copa Airlines flights from Panama City to Cali

Our best Copa Airlines deals on Panama City to Cali flight tickets
Copa Airlines
Feb 19
PTY4:00 pmPanama City Tocumen Intl
1h 50m
CLO5:50 pmCali Alfonso B. Aragon Intl
Feb 25
CLO5:03 amCali Alfonso B. Aragon Intl
1h 31m
PTY6:34 amPanama City Tocumen Intl
$244
Copa Airlines
Feb 13
PTY12:29 pmPanama City Tocumen Intl
1h 41m
CLO2:10 pmCali Alfonso B. Aragon Intl
Feb 17
CLO8:48 amCali Alfonso B. Aragon Intl
1h 32m
PTY10:20 amPanama City Tocumen Intl
$286
Copa Airlines
Apr 15
PTY9:25 amPanama City Tocumen Intl
1h 41m
CLO11:06 amCali Alfonso B. Aragon Intl
May 15
CLO3:10 pmCali Alfonso B. Aragon Intl
1h 34m
PTY4:44 pmPanama City Tocumen Intl
$287

Avianca flights from Panama City to Cali

Our best Avianca deals on Panama City to Cali flight tickets
Avianca
Mar 6
PTY9:45 amPanama City Tocumen Intl
5h 00m
1 stop
CLO2:45 pmCali Alfonso B. Aragon Intl
Mar 10
CLO8:15 pmCali Alfonso B. Aragon Intl
4h 45m
1 stop
PTY1:00 amPanama City Tocumen Intl
$250
Avianca
Feb 16
PTY5:50 pmPanama City Tocumen Intl
4h 45m
1 stop
CLO10:35 pmCali Alfonso B. Aragon Intl
Feb 20
CLO9:50 amCali Alfonso B. Aragon Intl
4h 10m
1 stop
PTY2:00 pmPanama City Tocumen Intl
$251
Avianca
Feb 13
PTY9:45 amPanama City Tocumen Intl
5h 00m
1 stop
CLO2:45 pmCali Alfonso B. Aragon Intl
Feb 17
CLO11:50 amCali Alfonso B. Aragon Intl
5h 05m
1 stop
PTY4:55 pmPanama City Tocumen Intl
$265

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Panama City to Cali that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 2/20

12:29 pm-2:10 pm

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Tue 2/24

5:03 am-6:34 am

Nonstop1h 31m

$244

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 3/6

9:45 am-2:45 pm

1 stop5h 00m

Cali Alfonso B. Aragon Intl

Tue 3/10

8:15 pm-1:00 am

1 stop4h 45m

$250

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 2/16

5:50 pm-10:35 pm

1 stop4h 45m

Cali Alfonso B. Aragon Intl

Fri 2/20

9:50 am-2:00 pm

1 stop4h 10m

$251

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 2/27

2:55 am-9:30 am

1 stop6h 35m

Cali Alfonso B. Aragon Intl

Fri 3/13

11:50 am-4:55 pm

1 stop5h 05m

$276

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sun 3/1

9:25 am-11:04 am

Nonstop1h 39m

Cali Alfonso B. Aragon Intl

Sun 3/29

5:03 am-6:34 am

Nonstop1h 31m

$286

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 4/15

9:25 am-11:06 am

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Fri 5/15

3:10 pm-4:44 pm

Nonstop1h 34m

$287

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Tue 3/17

2:55 pm-7:30 pm

1 stop4h 35m

Cali Alfonso B. Aragon Intl

Sun 3/22

6:45 pm-1:00 am

1 stop6h 15m

$302

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Tue 3/17

9:45 am-10:03 pm

1 stop12h 18m

Cali Alfonso B. Aragon Intl

Sun 3/22

10:51 pm-4:55 pm

2 stops18h 04m

$323

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 3/6

9:45 am-2:45 pm

1 stop5h 00m

Cali Alfonso B. Aragon Intl

Thu 3/12

3:11 pm-4:44 pm

Nonstop1h 33m

$324

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 3/5

2:55 am-7:10 am

1 stop4h 15m

Cali Alfonso B. Aragon Intl

Fri 3/13

8:48 am-10:20 am

Nonstop1h 32m

$325

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Cali from

How to get the cheapest flight ticket from Panama City to Cali

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Cali?

What is the cheapest month to fly to Cali?

The cheapest month to fly to Cali from Panama City is in May. Flight prices, which tend to average around $197, are often lower during this time because this is during the off-season. If you’re not able to fly to Cali in May, then February is your next best option. Flight prices from Panama City to Cali during February average around $211.

What is the cheapest day to depart on your flight to Cali?

The cheapest day to depart on your flight to Cali is on a Saturday when prices can be found for as low as $245. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $292. These prices are subject to change though, so be sure to set up a Price Alert for flights to Cali.

What is the cheapest time of day to depart on your flight to Cali?

Our most recent data shows that the best time of day to fly to Cali is in the morning. Flights from Panama City to Cali during this time can be as low as $266. In the evening is when there is more demand to fly to Cali, so prices are often more expensive at around $318 per ticket.

What is the cheapest Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl flight route?

Fly from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl for the best Panama City Tocumen Intl - Cali Alfonso B. Aragon Intl flight prices

How far in advance should I book a flight to Cali?

You are more likely to see cheaper flights to Cali from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cali for around $245 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cali from Panama City for as low as $189 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl flights?

There is only 1 cabin class available to choose from on Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Cali flights?

No. A direct flight is the cheapest option for a flight between Panama City to Cali.

How have Panama City to Cali flight prices changed over time?

As of February 2026, prices for Panama City to Cali flights are approximately 9% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Cali

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cali according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cali (PTY to CLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cali

Best Price Found

$156

Fastest flight time

1h 40m

Direct flights

Mon, Tue, Thu, Fri, Sat and Sun

Airports in Cali

1 airport
The best one-way flight to Cali from Panama City in the past 72 hours is $156. The best round-trip flight deal from Panama City to Cali found on momondo in the last 72 hours is $221.
The fastest flight from Panama City to Cali takes 1h 40m
Direct flights go from Panama City to Cali on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is Copa Airlines.
There is 1 airport in Cali. From Panama City there are direct flights to Cali Alfonso B. Aragon Intl (CLO).
  • How far is Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl by plane?

    Cali Alfonso B. Aragon Intl is 433.7 mi away from Panama City Tocumen Intl. Flights usually cover this in 1h 40m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport.

  • What documentation or ID do you need to fly to Cali Alfonso B. Aragon Intl Airport?

    The required travel and health documents for your Cali Alfonso B. Aragon Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cali Alfonso B. Aragon Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Panama City to Cali?

  • What is the most popular airline from Panama City to Cali?

Best airlines flying from Panama City to Cali

Compare and see reviews for airlines that fly from Panama City to Cali with momondo
Airline
Rating
Free Cancellation
Price
WingoPriceFrom $71Free CancellationRating
0.0
0 reviews
Search Wingo flights
Copa AirlinesPriceFrom $112Free CancellationRating
7.5
1,557 reviews
Search Copa Airlines flights
AviancaPriceFrom $162Free CancellationRating
6.5
2,499 reviews
Search Avianca flights
  • Copa Airlines Flights From Panama City to Cali

    Copa Airlines operates around 24 flights from Panama City to Cali every week. The average price of these flights found in the last 72 hours has been $266, but momondo users have found Copa Airlines deals from Panama City to Cali from as low as $112 round-trip. Copa Airlines has been scored 7.5/10 in 1,557 reviews.

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cali?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Cali. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Cali with flexible booking policies on momondo?

Yes. All flights to Cali from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Cali?

momondo provides multiple filters to help you find the best flight to Cali from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Cali right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Cali flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Cali trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 3/7
Sat 3/14

Find better results for your trip to Colombia