Cheap flights from Panama City to Cali from $145

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cali departing on 9/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Copa Airlines Logo
12:43 pm - 2:25 pmPTY-CLO
1h 42mnonstop
Copa Airlines Logo
8:48 am - 10:20 amCLO-PTY
1h 32mnonstop
$267Copa Airlines
Find Deal
Fri, Oct 24 - Sun, Nov 9
Avianca Logo
3:20 am - 7:35 amPTY-CLO
4h 15m1 stop
Avianca Logo
4:56 pm - 9:10 pmCLO-PTY
4h 14m1 stop
$273Avianca
Find Deal
Sat, Oct 18 - Fri, Oct 24
Copa Airlines Logo
9:20 am - 11:01 amPTY-CLO
1h 41mnonstop
Copa Airlines Logo
8:48 am - 10:20 amCLO-PTY
1h 32mnonstop
$278Copa Airlines
Find Deal
Fri, Dec 5 - Sun, Dec 7
Copa Airlines Logo
12:29 pm - 2:11 pmPTY-CLO
1h 42mnonstop
Copa Airlines Logo
5:01 am - 6:34 amCLO-PTY
1h 33mnonstop
$288Copa Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Avianca Logo
2:55 am - 7:10 amPTY-CLO
4h 15m1 stop
Avianca Logo
11:50 am - 4:55 pmCLO-PTY
5h 05m1 stop
$293Avianca
Find Deal
Wed, Dec 3 - Thu, Dec 11
Copa Airlines Logo
9:20 am - 11:01 amPTY-CLO
1h 41mnonstop
Copa Airlines Logo
3:12 pm - 4:44 pmCLO-PTY
1h 32mnonstop
$299Copa Airlines
Find Deal
Sat, Nov 1 - Tue, Nov 18
Copa Airlines Logo
12:43 pm - 2:21 pmPTY-CLO
1h 38mnonstop
Copa Airlines Logo
3:23 pm - 4:54 pmCLO-PTY
1h 31mnonstop
$309Copa Airlines
Find Deal
Fri, Sep 19 - Tue, Sep 23
Copa Airlines Logo
9:21 am - 10:58 amPTY-CLO
1h 37mnonstop
Copa Airlines Logo
12:01 pm - 1:32 pmCLO-PTY
1h 31mnonstop
$311Copa Airlines
Find Deal
Thu, Sep 18 - Sun, Sep 21
 Logo
2:55 am - 7:10 amPTY-CLO
4h 15m1 stop
 Logo
3:12 pm - 4:44 pmCLO-PTY
1h 32mnonstop
Wed, Oct 29 - Mon, Nov 17
Avianca Logo
2:55 am - 7:35 amPTY-CLO
4h 40m1 stop
Avianca Logo
11:50 am - 4:55 pmCLO-PTY
5h 05m1 stop
$320Avianca
Find Deal
Fri, Oct 31 - Tue, Nov 18

Avianca flights from Panama City to Cali

Our best Avianca deals on Panama City to Cali flight tickets
Avianca
Sep 25
PTY3:20 amPanama City Tocumen Intl
4h 15m
1 stop
CLO7:35 amCali Alfonso B. Aragon Intl
Sep 29
CLO11:23 amCali Alfonso B. Aragon Intl
5h 07m
1 stop
PTY4:30 pmPanama City Tocumen Intl
Avianca
Dec 3
PTY2:55 amPanama City Tocumen Intl
4h 15m
1 stop
CLO7:10 amCali Alfonso B. Aragon Intl
Dec 11
CLO11:50 amCali Alfonso B. Aragon Intl
5h 05m
1 stop
PTY4:55 pmPanama City Tocumen Intl
Avianca
Oct 31
PTY2:55 amPanama City Tocumen Intl
4h 40m
1 stop
CLO7:35 amCali Alfonso B. Aragon Intl
Nov 18
CLO11:50 amCali Alfonso B. Aragon Intl
5h 05m
1 stop
PTY4:55 pmPanama City Tocumen Intl

Copa Airlines flights from Panama City to Cali

Our best Copa Airlines deals on Panama City to Cali flight tickets
Copa Airlines
Sep 19
PTY12:43 pmPanama City Tocumen Intl
1h 38m
CLO2:21 pmCali Alfonso B. Aragon Intl
Sep 22
CLO12:01 pmCali Alfonso B. Aragon Intl
1h 31m
PTY1:32 pmPanama City Tocumen Intl
Copa Airlines
Dec 5
PTY9:20 amPanama City Tocumen Intl
1h 41m
CLO11:01 amCali Alfonso B. Aragon Intl
Dec 7
CLO8:48 amCali Alfonso B. Aragon Intl
1h 32m
PTY10:20 amPanama City Tocumen Intl
Copa Airlines
Dec 4
PTY12:29 pmPanama City Tocumen Intl
1h 42m
CLO2:11 pmCali Alfonso B. Aragon Intl
Dec 11
CLO5:01 amCali Alfonso B. Aragon Intl
1h 33m
PTY6:34 amPanama City Tocumen Intl

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Panama City to Cali that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 10/24

12:43 pm-2:25 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Sun 11/9

8:48 am-10:20 am

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sat 10/18

3:20 am-7:35 am

1 stop4h 15m

Cali Alfonso B. Aragon Intl

Fri 10/24

4:56 pm-9:10 pm

1 stop4h 14m

$273

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 12/5

9:20 am-11:01 am

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Sun 12/7

8:48 am-10:20 am

Nonstop1h 32m

$278

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 12/4

12:29 pm-2:11 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Thu 12/11

5:01 am-6:34 am

Nonstop1h 33m

$288

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 12/3

2:55 am-7:10 am

1 stop4h 15m

Cali Alfonso B. Aragon Intl

Thu 12/11

11:50 am-4:55 pm

1 stop5h 05m

$293

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sat 11/1

9:20 am-11:01 am

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Tue 11/18

3:12 pm-4:44 pm

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 9/19

12:43 pm-2:21 pm

Nonstop1h 38m

Cali Alfonso B. Aragon Intl

Tue 9/23

3:23 pm-4:54 pm

Nonstop1h 31m

$309

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 9/18

9:21 am-10:58 am

Nonstop1h 37m

Cali Alfonso B. Aragon Intl

Sun 9/21

12:01 pm-1:32 pm

Nonstop1h 31m

$311

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 10/29

2:55 am-7:10 am

1 stop4h 15m

Cali Alfonso B. Aragon Intl

Mon 11/17

3:12 pm-4:44 pm

Nonstop1h 32m

$316

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 10/31

2:55 am-7:35 am

1 stop4h 40m

Cali Alfonso B. Aragon Intl

Tue 11/18

11:50 am-4:55 pm

1 stop5h 05m

$320

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Cali from

How to get the cheapest flight ticket from Panama City to Cali

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cali?

The cheapest month to fly to Cali from Panama City is in April. Flight prices, which tend to average around $188, are often lower during this time because this is during the off-season. If you’re not able to fly to Cali in April, then May is your next best option. Flight prices from Panama City to Cali during May average around $197.

What is the cheapest day to depart on your flight to Cali?

The cheapest day to depart on your flight to Cali is on a Monday when prices can be found for as low as $266. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $370. These prices are subject to change though, so be sure to set up a Price Alert for flights to Cali.

What is the cheapest time of day to depart on your flight to Cali?

Our most recent data shows that the best time of day to fly to Cali is in the morning. Flights from Panama City to Cali during this time can be as low as $266. In the evening is when there is more demand to fly to Cali, so prices are often more expensive at around $318 per ticket.

What is the cheapest Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl flight route?

Fly from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl for the best Panama City Tocumen Intl - Cali Alfonso B. Aragon Intl flight prices

How far in advance should I book a flight to Cali?

You are more likely to see cheaper flights to Cali from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cali for around $226 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cali from Panama City for as low as $210 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl flights?

There is only 1 cabin class available to choose from on Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Cali flights?

No. A direct flight is the cheapest option for a flight between Panama City to Cali.

How have Panama City to Cali flight prices changed over time?

As of September 2025, prices for Panama City to Cali flights are approximately 18% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Cali

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cali according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cali (PTY to CLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cali

Best Price Found

$166

Fastest flight time

1h 37m

Direct flights

Every day

Airports in Cali

1 airport
The best one-way flight to Cali from Panama City in the past 72 hours is $166. The best round-trip flight deal from Panama City to Cali found on momondo in the last 72 hours is $266.
The fastest flight from Panama City to Cali takes 1h 37m
Direct flights go from Panama City to Cali every day.
There is 1 airport near Cali: Cali Alfonso B. Aragon Intl (CLO)
  • How far is Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl by plane?

    Cali Alfonso B. Aragon Intl is 433.7 mi away from Panama City Tocumen Intl. Flights usually cover this in 1h 37m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport.

  • What documentation or ID do you need to fly to Cali Alfonso B. Aragon Intl Airport?

    The required travel and health documents for your Cali Alfonso B. Aragon Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cali Alfonso B. Aragon Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Panama City to Cali?

  • What is the most popular airline from Panama City to Cali?

Best airlines flying from Panama City to Cali

Compare and see reviews for airlines that fly from Panama City to Cali with momondo
Airline
Rating
Free Cancellation
Price
WingoPriceFrom $71Free CancellationRating
7.3
136 reviews
Search Wingo flights
Copa AirlinesPriceFrom $112Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights
AviancaPriceFrom $210Free CancellationRating
6.7
2,435 reviews
Search Avianca flights
  • Copa Airlines Flights From Panama City to Cali

    Copa Airlines operates around 26 flights from Panama City to Cali every week. The average price of these flights found in the last 72 hours has been $266, but momondo users have found Copa Airlines deals from Panama City to Cali from as low as $112 round-trip. Copa Airlines has been scored 7.6/10 in 1,531 reviews.

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cali?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Cali. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Cali with flexible booking policies on momondo?

Yes. All flights to Cali from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Cali?

momondo provides multiple filters to help you find the best flight to Cali from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Cali right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Cali flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Wed 10/15
Wed 10/22

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