Cheap flights from Panama City to Cali from $161

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cali departing on 12/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Copa Airlines Logo
9:55 pm - 11:37 pm
PTY
-
CLO
1h 42mnonstop
Copa Airlines Logo
8:48 am - 10:20 am
CLO
-
PTY
1h 32mnonstop
$299Copa Airlines
Wed, Dec 31 - Thu, Jan 15
Avianca Logo
9:45 am - 2:45 pm
PTY
-
CLO
5h 00m1 stop
Avianca Logo
8:40 am - 2:00 pm
CLO
-
PTY
5h 20m1 stop
$305Avianca
Mon, Jan 5 - Mon, Mar 16
Avianca Logo
2:55 pm - 7:55 pm
PTY
-
CLO
5h 00m1 stop
Avianca Logo
8:15 pm - 12:40 am
CLO
-
PTY
4h 25m1 stop
$307Avianca
Thu, Dec 25 - Wed, Dec 31
Copa Airlines Logo
12:29 pm - 2:11 pm
PTY
-
CLO
1h 42mnonstop
Copa Airlines Logo
8:48 am - 10:20 am
CLO
-
PTY
1h 32mnonstop
$310Copa Airlines
Mon, Dec 29 - Wed, Jan 21
Avianca Logo
2:55 pm - 7:30 pm
PTY
-
CLO
4h 35m1 stop
Avianca Logo
8:15 pm - 12:40 am
CLO
-
PTY
4h 25m1 stop
$316Avianca
Wed, Dec 24 - Fri, Jan 9
Copa Airlines Logo
3:55 pm - 5:37 pm
PTY
-
CLO
1h 42mnonstop
Copa Airlines Logo
12:03 pm - 1:35 pm
CLO
-
PTY
1h 32mnonstop
$320Copa Airlines
Fri, Dec 26 - Tue, Jan 6
Avianca Logo
5:50 pm - 11:10 pm
PTY
-
CLO
5h 20m1 stop
Avianca Logo
8:15 pm - 1:00 am
CLO
-
PTY
4h 45m1 stop
$323Avianca
Wed, Dec 24 - Sun, Jan 11
Copa Airlines Logo
3:55 pm - 5:37 pm
PTY
-
CLO
1h 42mnonstop
Copa Airlines Logo
12:03 pm - 1:35 pm
CLO
-
PTY
1h 32mnonstop
$329Copa Airlines
Fri, Dec 26 - Sun, Jan 25
Copa Airlines Logo
9:20 am - 11:01 am
PTY
-
CLO
1h 41mnonstop
Copa Airlines Logo
12:03 pm - 1:35 pm
CLO
-
PTY
1h 32mnonstop
$340Copa Airlines
Sat, Dec 27 - Tue, Jan 6
Copa Airlines Logo
12:29 pm - 2:11 pm
PTY
-
CLO
1h 42mnonstop
Copa Airlines Logo
6:37 pm - 8:10 pm
CLO
-
PTY
1h 33mnonstop
$342Copa Airlines
Tue, Dec 23 - Fri, Dec 26

Avianca flights from Panama City to Cali

Our best Avianca deals on Panama City to Cali flight tickets
Avianca
Jan 5
PTY9:45 amPanama City Tocumen Intl
5h 00m
1 stop
CLO2:45 pmCali Alfonso B. Aragon Intl
Mar 16
CLO8:40 amCali Alfonso B. Aragon Intl
5h 20m
1 stop
PTY2:00 pmPanama City Tocumen Intl
Avianca
Dec 25
PTY2:55 pmPanama City Tocumen Intl
5h 00m
1 stop
CLO7:55 pmCali Alfonso B. Aragon Intl
Dec 31
CLO8:15 pmCali Alfonso B. Aragon Intl
4h 25m
1 stop
PTY12:40 amPanama City Tocumen Intl
Avianca
Dec 27
PTY2:55 pmPanama City Tocumen Intl
5h 15m
1 stop
CLO8:10 pmCali Alfonso B. Aragon Intl
Jan 9
CLO8:15 pmCali Alfonso B. Aragon Intl
4h 25m
1 stop
PTY12:40 amPanama City Tocumen Intl

Copa Airlines flights from Panama City to Cali

Our best Copa Airlines deals on Panama City to Cali flight tickets
Copa Airlines
Dec 31
PTY9:55 pmPanama City Tocumen Intl
1h 42m
CLO11:37 pmCali Alfonso B. Aragon Intl
Jan 31
CLO8:48 amCali Alfonso B. Aragon Intl
1h 32m
PTY10:20 amPanama City Tocumen Intl
Copa Airlines
Dec 29
PTY12:29 pmPanama City Tocumen Intl
1h 42m
CLO2:11 pmCali Alfonso B. Aragon Intl
Jan 21
CLO8:48 amCali Alfonso B. Aragon Intl
1h 32m
PTY10:20 amPanama City Tocumen Intl
Copa Airlines
Dec 27
PTY9:20 amPanama City Tocumen Intl
1h 41m
CLO11:01 amCali Alfonso B. Aragon Intl
Jan 20
CLO8:48 amCali Alfonso B. Aragon Intl
1h 32m
PTY10:20 amPanama City Tocumen Intl

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 17, 2025.
Use the filters below to find and compare flights from Panama City to Cali that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 12/31

9:55 pm-11:37 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Thu 1/15

8:48 am-10:20 am

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 1/5

9:45 am-2:45 pm

1 stop5h 00m

Cali Alfonso B. Aragon Intl

Mon 3/16

8:40 am-2:00 pm

1 stop5h 20m

$305

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 12/25

2:55 pm-7:55 pm

1 stop5h 00m

Cali Alfonso B. Aragon Intl

Wed 12/31

8:15 pm-12:40 am

1 stop4h 25m

$307

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 12/29

12:29 pm-2:11 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Wed 1/21

8:48 am-10:20 am

Nonstop1h 32m

$310

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 12/24

2:55 pm-7:30 pm

1 stop4h 35m

Cali Alfonso B. Aragon Intl

Fri 1/9

8:15 pm-12:40 am

1 stop4h 25m

$316

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 12/26

3:55 pm-5:37 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Tue 1/6

12:03 pm-1:35 pm

Nonstop1h 32m

$320

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 12/24

5:50 pm-11:10 pm

1 stop5h 20m

Cali Alfonso B. Aragon Intl

Sun 1/11

8:15 pm-1:00 am

1 stop4h 45m

$323

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 12/26

3:55 pm-5:37 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Sun 1/25

12:03 pm-1:35 pm

Nonstop1h 32m

$329

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sat 12/27

9:20 am-11:01 am

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Tue 1/6

12:03 pm-1:35 pm

Nonstop1h 32m

$340

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Tue 12/23

12:29 pm-2:11 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Fri 12/26

6:37 pm-8:10 pm

Nonstop1h 33m

$342

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Cali from

How to get the cheapest flight ticket from Panama City to Cali

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cali?

The cheapest month to fly to Cali from Panama City is in May. Flight prices, which tend to average around $187, are often lower during this time because this is during the off-season. If you’re not able to fly to Cali in May, then February is your next best option. Flight prices from Panama City to Cali during February average around $212.

What is the cheapest day to depart on your flight to Cali?

The cheapest day to depart on your flight to Cali is on a Saturday when prices can be found for as low as $260. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $292. These prices are subject to change though, so be sure to set up a Price Alert for flights to Cali.

What is the cheapest time of day to depart on your flight to Cali?

Our most recent data shows that the best time of day to fly to Cali is in the morning. Flights from Panama City to Cali during this time can be as low as $266. In the evening is when there is more demand to fly to Cali, so prices are often more expensive at around $318 per ticket.

What is the cheapest Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl flight route?

Fly from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl for the best Panama City Tocumen Intl - Cali Alfonso B. Aragon Intl flight prices

How far in advance should I book a flight to Cali?

You are more likely to see cheaper flights to Cali from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cali for around $241 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cali from Panama City for as low as $189 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl flights?

There is only 1 cabin class available to choose from on Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Cali flights?

No. A direct flight is the cheapest option for a flight between Panama City to Cali.

How have Panama City to Cali flight prices changed over time?

As of December 2025, prices for Panama City to Cali flights are approximately 14% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Cali

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cali according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cali (PTY to CLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cali

Best Price Found

$173

Fastest flight time

1h 29m

Direct flights

Mon, Tue, Wed, Thu, Sat and Sun

Airports in Cali

1 airport
The best one-way flight to Cali from Panama City in the past 72 hours is $173. The best round-trip flight deal from Panama City to Cali found on momondo in the last 72 hours is $298.
The fastest flight from Panama City to Cali takes 1h 29m
Direct flights go from Panama City to Cali on Monday, Tuesday, Wednesday, Thursday, Saturday and Sunday. The only airline offering direct flights is Copa Airlines.
There is 1 airport in Cali. From Panama City there are direct flights to Cali Alfonso B. Aragon Intl (CLO).
  • How far is Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl by plane?

    Cali Alfonso B. Aragon Intl is 433.7 mi away from Panama City Tocumen Intl. Flights usually cover this in 1h 29m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cali Alfonso B. Aragon Intl Airport.

  • What documentation or ID do you need to fly to Cali Alfonso B. Aragon Intl Airport?

    The required travel and health documents for your Cali Alfonso B. Aragon Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cali Alfonso B. Aragon Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Panama City to Cali?

  • What is the most popular airline from Panama City to Cali?

Best airlines flying from Panama City to Cali

Compare and see reviews for airlines that fly from Panama City to Cali with momondo
Airline
Rating
Free Cancellation
Price
WingoPriceFrom $73Free CancellationRating
0.0
0 reviews
Search Wingo flights
Copa AirlinesPriceFrom $122Free CancellationRating
7.6
1,556 reviews
Search Copa Airlines flights
AviancaPriceFrom $211Free CancellationRating
6.6
2,487 reviews
Search Avianca flights
  • Copa Airlines Flights From Panama City to Cali

    Copa Airlines operates around 29 flights from Panama City to Cali every week. The average price of these flights found in the last 72 hours has been $266, but momondo users have found Copa Airlines deals from Panama City to Cali from as low as $122 round-trip. Copa Airlines has been scored 7.6/10 in 1,556 reviews.

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cali?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Cali. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Cali with flexible booking policies on momondo?

Yes. All flights to Cali from Panama City on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama City to Cali?

momondo provides multiple filters to help you find the best flight to Cali from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Cali right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Cali flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Fri 1/16
Fri 1/23

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