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Cheap flights from Panama City, Florida to Key West from $165

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Key West departing on 8/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City, Florida to Key West

Cheap round-trip flights

Delta Logo
6:00 am - 10:56 amECP-EYW
3h 56m1 stop
Delta Logo
7:00 am - 10:34 amEYW-ECP
4h 34m1 stop
$287Delta
Find Deal
Tue, Sep 2 - Tue, Sep 9
Delta Logo
1:53 pm - 8:12 pmECP-EYW
5h 19m1 stop
Delta Logo
6:20 pm - 11:06 pmEYW-ECP
5h 46m1 stop
$297Delta
Find Deal
Thu, Sep 4 - Tue, Sep 9
American Airlines Logo
11:18 am - 6:38 pmECP-EYW
6h 20m2 stops
American Airlines Logo
8:10 am - 1:47 pmEYW-ECP
6h 37m1 stop
$302American Airlines
Find Deal
Thu, Dec 11 - Tue, Dec 16
Delta Logo
9:24 am - 5:12 pmECP-EYW
6h 48m1 stop
Delta Logo
6:20 pm - 11:06 pmEYW-ECP
5h 46m1 stop
$307Delta
Find Deal
Tue, Aug 26 - Wed, Sep 3
Delta Logo
6:00 am - 10:56 amECP-EYW
3h 56m1 stop
Delta Logo
6:20 pm - 11:06 pmEYW-ECP
5h 46m1 stop
$313Delta
Find Deal
Sat, Sep 6 - Wed, Sep 10
Delta Logo
6:00 am - 10:56 amECP-EYW
3h 56m1 stop
Delta Logo
6:20 pm - 11:06 pmEYW-ECP
5h 46m1 stop
$317Delta
Find Deal
Tue, Aug 26 - Sat, Aug 30
Delta Logo
6:00 am - 1:05 pmECP-EYW
6h 05m1 stop
Delta Logo
6:20 pm - 11:06 pmEYW-ECP
5h 46m1 stop
$329Delta
Find Deal
Sun, Aug 31 - Wed, Sep 3
Delta Logo
7:10 am - 1:05 pmECP-EYW
4h 55m1 stop
Delta Logo
6:20 pm - 2:41 pmEYW-ECP
21h 21m2 stops
$330Delta
Find Deal
Tue, Sep 2 - Sat, Sep 6
Delta Logo
6:00 am - 1:05 pmECP-EYW
6h 05m1 stop
Delta Logo
6:20 pm - 11:06 pmEYW-ECP
5h 46m1 stop
$334Delta
Find Deal
Fri, Sep 5 - Fri, Sep 5
American Airlines Logo
11:18 am - 6:30 pmECP-EYW
6h 12m1 stop
American Airlines Logo
8:10 am - 1:47 pmEYW-ECP
6h 37m1 stop
$338American Airlines
Find Deal
Thu, Dec 11 - Tue, Dec 16

Delta flights from Panama City, Florida to Key West

Our best Delta deals on Panama City, Florida to Key West flight tickets
Delta
Sep 2
ECP6:00 amPanama City NW Florida Beaches
3h 56m
1 stop
EYW10:56 amKey West
Sep 9
EYW7:00 amKey West
4h 34m
1 stop
ECP10:34 amPanama City NW Florida Beaches
$287
Find similar
Delta
Sep 4
ECP1:53 pmPanama City NW Florida Beaches
5h 19m
1 stop
EYW8:12 pmKey West
Sep 9
EYW6:20 pmKey West
5h 46m
1 stop
ECP11:06 pmPanama City NW Florida Beaches
$297
Find similar
Delta
Aug 26
ECP9:24 amPanama City NW Florida Beaches
6h 48m
1 stop
EYW5:12 pmKey West
Sep 3
EYW6:20 pmKey West
5h 46m
1 stop
ECP11:06 pmPanama City NW Florida Beaches
$307
Find similar

American Airlines flights from Panama City, Florida to Key West

Our best American Airlines deals on Panama City, Florida to Key West flight tickets
American Airlines
Dec 11
ECP11:18 amPanama City NW Florida Beaches
6h 20m
2 stops
EYW6:38 pmKey West
Dec 16
EYW8:10 amKey West
6h 37m
1 stop
ECP1:47 pmPanama City NW Florida Beaches
$302
Find similar
American Airlines
Dec 11
ECP11:18 amPanama City NW Florida Beaches
6h 12m
1 stop
EYW6:30 pmKey West
Dec 16
EYW8:10 amKey West
6h 37m
1 stop
ECP1:47 pmPanama City NW Florida Beaches
$338
Find similar
American Airlines
Dec 6
ECP11:18 amPanama City NW Florida Beaches
6h 12m
1 stop
EYW6:30 pmKey West
Dec 13
EYW8:10 amKey West
6h 37m
1 stop
ECP1:47 pmPanama City NW Florida Beaches
$343
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 9/2

6:00 am-10:56 am

1 stop3h 56m

Key West

Tue 9/9

7:00 am-10:34 am

1 stop4h 34m

$287

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 9/4

1:53 pm-8:12 pm

1 stop5h 19m

Key West

Tue 9/9

6:20 pm-11:06 pm

1 stop5h 46m

$297

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 12/11

11:18 am-6:38 pm

2 stops6h 20m

Key West

Tue 12/16

8:10 am-1:47 pm

1 stop6h 37m

$302

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 8/26

9:24 am-5:12 pm

1 stop6h 48m

Key West

Wed 9/3

6:20 pm-11:06 pm

1 stop5h 46m

$307

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Sat 9/6

6:00 am-10:56 am

1 stop3h 56m

Key West

Wed 9/10

6:20 pm-11:06 pm

1 stop5h 46m

$313

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 8/26

6:00 am-10:56 am

1 stop3h 56m

Key West

Sat 8/30

6:20 pm-11:06 pm

1 stop5h 46m

$317

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Sun 8/31

6:00 am-1:05 pm

1 stop6h 05m

Key West

Wed 9/3

6:20 pm-11:06 pm

1 stop5h 46m

$329

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 9/2

7:10 am-1:05 pm

1 stop4h 55m

Key West

Sat 9/6

6:20 pm-2:41 pm

2 stops21h 21m

$330

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Fri 9/5

6:00 am-1:05 pm

1 stop6h 05m

Key West

Fri 9/5

6:20 pm-11:06 pm

1 stop5h 46m

$334

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 12/11

11:18 am-6:30 pm

1 stop6h 12m

Key West

Tue 12/16

8:10 am-1:47 pm

1 stop6h 37m

$338

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
1
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See travel insights to Key West from

How to get the cheapest flight ticket from Panama City, Florida to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, July is the cheapest month to fly from Panama City, Florida to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $407. If you are unable to visit Key West during the month of July, then departing from Panama City, Florida during the month December is also very affordable. Most momondo users find prices during this month for around $435.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Panama City, Florida is on a Sunday. momondo users have found tickets for Sunday departures for as low as $414. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Panama City, Florida to Key West for around $628.

When to book flights from Panama City, Florida to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Key West (ECP to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Key West

Best Price Found

$165

Fastest flight time

3h 56m

Direct flights

None

Airports in Key West

1 airport
The best one-way flight to Key West from Panama City, Florida in the past 72 hours is $165. The best round-trip flight deal from Panama City, Florida to Key West found on momondo in the last 72 hours is $287.
The fastest flight from Panama City, Florida to Key West takes 3h 56m
There are no direct flights from Panama City, Florida to Key West. Popular non-direct route for this connection is Panama City NW Florida Beaches Airport - Key West Airport.
There is 1 airport near Key West: Key West (EYW)
Search flight deals

  • How far is Panama City NW Florida Beaches to Key West by plane?

    Panama City NW Florida Beaches and Key West are 453.5 mi apart from one another. 3h 56m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Key West Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Key West Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Key West Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Key West Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City NW Florida Beaches Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to Key West?

Best airlines flying from Panama City, Florida to Key West

Compare and see reviews for airlines that fly from Panama City, Florida to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $322Free CancellationRating
8.0
7,981 reviews
Search Delta flights
American AirlinesPriceFrom $358Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Key West?

It is quick and easy to find Panama City to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Panama City to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Key West?

Once all potential Panama City to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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