What airlines fly to Key West?

Silver Airways, American Airlines and Delta are the top three most popular airlines that fly to Key West from Panama City, Florida according to our data. Silver Airways is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Key West. Keep in mind that there are 3 different airlines that fly to Key West on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Key West Airport?

Prices for flights from Panama City NW Florida Beaches Airport to Key West Airport are updated daily.

How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Key West Airport?

There are 2 operators available for flights from Panama City NW Florida Beaches Airport to Key West Airport as of September 2025.

How old do you have to be to fly from Panama City NW Florida Beaches Airport to Key West Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City NW Florida Beaches Airport to Key West Airport.

What documentation or ID do you need to fly to Key West Airport?

The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$277 Cheap Flights from Panama City to Key West in 2025/26

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Find the cheapest flights from Panama City, Florida to Key West

Round-trip

One-way

Last minute

Cheap round-trip flights

1:25 pm - 8:06 pmECP-EYW

5h 41m1 stop

6:18 pm - 10:37 pmEYW-ECP

5h 19m1 stop

$307Delta

Find Deal

Tue, Nov 4 - Tue, Nov 18

1:25 pm - 8:06 pmECP-EYW

5h 41m1 stop

6:18 pm - 10:57 pmEYW-ECP

5h 39m1 stop

$317Delta

Find Deal

Tue, Nov 4 - Fri, Nov 14

7:15 am - 4:12 pmECP-EYW

7h 57m1 stop

7:00 am - 4:47 pmEYW-ECP

10h 47m2 stops

$322American Airlines

Find Deal

Thu, Dec 11 - Tue, Dec 16

7:02 am - 2:06 pmECP-EYW

6h 04m1 stop

7:25 am - 1:14 pmEYW-ECP

6h 49m1 stop

$323Delta

Find Deal

Wed, Dec 17 - Thu, Dec 25

1:25 pm - 8:06 pmECP-EYW

5h 41m1 stop

6:18 pm - 10:57 pmEYW-ECP

5h 39m1 stop

$327Delta

Find Deal

Fri, Nov 7 - Thu, Nov 13

7:15 am - 3:57 pmECP-EYW

7h 42m1 stop

6:31 am - 1:51 pmEYW-ECP

8h 20m2 stops

$332American Airlines

Find Deal

Mon, Jan 5 - Mon, Jan 12

1:59 pm - 8:56 pmECP-EYW

5h 57m1 stop

7:25 am - 1:14 pmEYW-ECP

6h 49m1 stop

$333Delta

Find Deal

Mon, Dec 22 - Thu, Dec 25

1:25 pm - 8:06 pmECP-EYW

5h 41m1 stop

6:18 pm - 1:00 pmEYW-ECP

19h 42m2 stops

$341Delta

Find Deal

Tue, Nov 4 - Tue, Nov 18

6:00 am - 1:02 pmECP-EYW

6h 02m1 stop

6:18 pm - 10:37 pmEYW-ECP

5h 19m1 stop

$348Delta

Find Deal

Mon, Nov 3 - Wed, Nov 12

1:25 pm - 8:06 pmECP-EYW

5h 41m1 stop

6:18 pm - 1:00 pmEYW-ECP

19h 42m2 stops

$351Delta

Find Deal

Fri, Nov 7 - Tue, Nov 18

American Airlines flights from Panama City, Florida to Key West

Our best American Airlines deals on Panama City, Florida to Key West flight tickets

American Airlines

Dec 11

ECP7:15 amPanama City NW Florida Beaches

7h 57m

1 stop

EYW4:12 pmKey West

Dec 16

EYW7:00 amKey West

10h 47m

2 stops

ECP4:47 pmPanama City NW Florida Beaches

$322

Find similar

American Airlines

Jan 5

ECP7:15 amPanama City NW Florida Beaches

7h 42m

1 stop

EYW3:57 pmKey West

Jan 12

EYW6:31 amKey West

8h 20m

2 stops

ECP1:51 pmPanama City NW Florida Beaches

$332

Find similar

American Airlines

Nov 5

ECP12:00 pmPanama City NW Florida Beaches

4h 51m

1 stop

EYW5:51 pmKey West

Nov 12

EYW7:31 amKey West

4h 58m

1 stop

ECP11:29 amPanama City NW Florida Beaches

$367

Find similar

Delta flights from Panama City, Florida to Key West

Our best Delta deals on Panama City, Florida to Key West flight tickets

Delta

Nov 4

ECP1:25 pmPanama City NW Florida Beaches

5h 41m

1 stop

EYW8:06 pmKey West

Nov 18

EYW6:18 pmKey West

5h 19m

1 stop

ECP10:37 pmPanama City NW Florida Beaches

$307

Find similar

Delta

Nov 4

ECP1:25 pmPanama City NW Florida Beaches

5h 41m

1 stop

EYW8:06 pmKey West

Nov 14

EYW6:18 pmKey West

5h 39m

1 stop

ECP10:57 pmPanama City NW Florida Beaches

$317

Find similar

Delta

Dec 17

ECP7:02 amPanama City NW Florida Beaches

6h 04m

1 stop

EYW2:06 pmKey West

Dec 25

EYW7:25 amKey West

6h 49m

1 stop

ECP1:14 pmPanama City NW Florida Beaches

$323

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Panama City, Florida to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 11/4

1:25 pm-8:06 pm

1 stop5h 41m

Key West

Tue 11/18

6:18 pm-10:37 pm

1 stop5h 19m

$307

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 11/4

1:25 pm-8:06 pm

1 stop5h 41m

Key West

Fri 11/14

6:18 pm-10:57 pm

1 stop5h 39m

$317

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 12/11

7:15 am-4:12 pm

1 stop7h 57m

Key West

Tue 12/16

7:00 am-4:47 pm

2 stops10h 47m

$322

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Wed 12/17

7:02 am-2:06 pm

1 stop6h 04m

Key West

Thu 12/25

7:25 am-1:14 pm

1 stop6h 49m

$323

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Fri 11/7

1:25 pm-8:06 pm

1 stop5h 41m

Key West

Thu 11/13

6:18 pm-10:57 pm

1 stop5h 39m

$327

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Mon 1/5

7:15 am-3:57 pm

1 stop7h 42m

Key West

Mon 1/12

6:31 am-1:51 pm

2 stops8h 20m

$332

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Mon 12/22

1:59 pm-8:56 pm

1 stop5h 57m

Key West

Thu 12/25

7:25 am-1:14 pm

1 stop6h 49m

$333

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 11/4

1:25 pm-8:06 pm

1 stop5h 41m

Key West

Tue 11/18

6:18 pm-1:00 pm

2 stops19h 42m

$341

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Mon 11/3

6:00 am-1:02 pm

1 stop6h 02m

Key West

Wed 11/12

6:18 pm-10:37 pm

1 stop5h 19m

$348

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Fri 11/7

1:25 pm-8:06 pm

1 stop5h 41m

Key West

Tue 11/18

6:18 pm-1:00 pm

2 stops19h 42m

$351

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Panama City, Florida to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Key West?

In general, July is the cheapest month to fly from Panama City, Florida to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $392. If you are unable to visit Key West during the month of July, then departing from Panama City, Florida during the month November is also very affordable. Most momondo users find prices during this month for around $393.

What is the cheapest day to depart on your flight to Key West?

On average, the least expensive day to fly to Key West from Panama City, Florida is on a Sunday. momondo users have found tickets for Sunday departures for as low as $414. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Panama City, Florida to Key West for around $628.

When to book flights from Panama City, Florida to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Key West according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Panama City, Florida to Key West (ECP to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Key West

Direct flights	None

There are no direct flights from Panama City, Florida to Key West. There are no popular flight routes from Panama City, Florida to Key West.

Search flight deals

How far is Panama City NW Florida Beaches to Key West by plane?
Panama City NW Florida Beaches and Key West are 453.5 mi apart from one another. 4h 40m is a normal flight duration for this route.
When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Key West Airport?
Prices for flights from Panama City NW Florida Beaches Airport to Key West Airport are updated daily.
How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Key West Airport?
There are 2 operators available for flights from Panama City NW Florida Beaches Airport to Key West Airport as of September 2025.
How old do you have to be to fly from Panama City NW Florida Beaches Airport to Key West Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City NW Florida Beaches Airport to Key West Airport.
What documentation or ID do you need to fly to Key West Airport?
The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Panama City, Florida to Key West?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Panama City, Florida to Key West is Delta (81% of total bookings). The next most popular airline is American Airlines (19%).

Best airlines flying from Panama City, Florida to Key West

Compare and see reviews for airlines that fly from Panama City, Florida to Key West with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $296	Free Cancellation	Rating 7.2 10,000 reviews		Search American Airlines flights
Delta	PriceFrom $306	Free Cancellation	Rating 7.9 7,957 reviews		Search Delta flights

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Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Key West?

It is quick and easy to find Panama City to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Panama City to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Key West?

Once all potential Panama City to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.