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Cheap flights from Panama City, Florida to Key West from $341

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Key West departing on 6/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Panama City, Florida to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 11:02 am
ECP
-
EYW
4h 02m
1 stop
Delta Logo
6:24 pm - 11:44 pm
EYW
-
ECP
6h 20m
1 stop
$341Delta
mié., jun. 10 - mié., jun. 17
Delta Logo
11:38 am - 5:23 pm
ECP
-
EYW
4h 45m
1 stop
Delta Logo
7:00 am - 10:13 am
EYW
-
ECP
4h 13m
1 stop
$347Delta
mar., ago. 4 - mié., ago. 12
Delta Logo
7:46 am - 1:29 pm
ECP
-
EYW
4h 43m
1 stop
Delta Logo
2:24 pm - 6:50 pm
EYW
-
ECP
5h 26m
1 stop
$351Delta
mar., ago. 4 - sáb., ago. 8
Delta Logo
6:00 am - 1:29 pm
ECP
-
EYW
6h 29m
1 stop
Delta Logo
2:35 pm - 7:37 pm
EYW
-
ECP
6h 02m
1 stop
$357Delta
mar., ago. 4 - jue., ago. 13
Delta Logo
2:43 pm - 7:51 pm
ECP
-
EYW
4h 08m
1 stop
Delta Logo
6:18 pm - 10:58 pm
EYW
-
ECP
5h 40m
1 stop
$361Delta
jue., ago. 6 - sáb., ago. 8
Delta Logo
2:43 pm - 7:51 pm
ECP
-
EYW
4h 08m
1 stop
Delta Logo
6:18 pm - 11:37 pm
EYW
-
ECP
6h 19m
1 stop
$367Delta
jue., ago. 6 - dom., ago. 9
Delta Logo
2:50 pm - 7:49 pm
ECP
-
EYW
3h 59m
1 stop
Delta Logo
11:48 am - 5:56 pm
EYW
-
ECP
7h 08m
1 stop
$377Delta
mié., may. 20 - jue., may. 28
Delta Logo
11:49 am - 5:23 pm
ECP
-
EYW
4h 34m
1 stop
Delta Logo
7:30 am - 12:50 pm
EYW
-
ECP
6h 20m
1 stop
$387Delta
mié., may. 20 - lun., may. 25
Delta Logo
1:50 pm - 7:49 pm
ECP
-
EYW
4h 59m
1 stop
Delta Logo
7:30 am - 10:53 am
EYW
-
ECP
4h 23m
1 stop
$403Delta
vie., may. 22 - vie., may. 29
Delta Logo
1:50 pm - 7:49 pm
ECP
-
EYW
4h 59m
1 stop
Delta Logo
6:19 pm - 11:01 pm
EYW
-
ECP
5h 42m
1 stop
$407Delta
mar., may. 12 - mar., may. 19

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Delta flights from Panama City, Florida to Key West

Our best Delta deals on Panama City, Florida to Key West flight tickets
Delta
Jun 10
ECP6:00 amPanama City NW Florida Beaches
4h 02m
1 stop
EYW11:02 amKey West
Jun 17
EYW6:24 pmKey West
6h 20m
1 stop
ECP11:44 pmPanama City NW Florida Beaches
$341
Delta
Aug 4
ECP11:38 amPanama City NW Florida Beaches
4h 45m
1 stop
EYW5:23 pmKey West
Aug 12
EYW7:00 amKey West
4h 13m
1 stop
ECP10:13 amPanama City NW Florida Beaches
$347
Delta
Aug 4
ECP7:46 amPanama City NW Florida Beaches
4h 43m
1 stop
EYW1:29 pmKey West
Aug 8
EYW2:24 pmKey West
5h 26m
1 stop
ECP6:50 pmPanama City NW Florida Beaches
$351

American Airlines flights from Panama City, Florida to Key West

Our best American Airlines deals on Panama City, Florida to Key West flight tickets
American Airlines
May 9
ECP10:50 amPanama City NW Florida Beaches
11h 08m
2 stops
EYW10:58 pmKey West
May 12
EYW5:25 pmKey West
6h 27m
1 stop
ECP10:52 pmPanama City NW Florida Beaches
$432
American Airlines
Jun 10
ECP7:05 amPanama City NW Florida Beaches
11h 05m
2 stops
EYW7:10 pmKey West
Jun 17
EYW7:29 pmKey West
5h 11m
1 stop
ECP11:40 pmPanama City NW Florida Beaches
$436
American Airlines
May 9
ECP10:50 amPanama City NW Florida Beaches
11h 08m
2 stops
EYW10:58 pmKey West
May 12
EYW3:58 pmKey West
7h 54m
2 stops
ECP10:52 pmPanama City NW Florida Beaches
$437

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated abril 30, 2026.
Use the filters below to find and compare flights from Panama City, Florida to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

mié. 6/10

6:00 am-11:02 am

1 stop4h 02m

Key West

mié. 6/17

6:24 pm-11:44 pm

1 stop6h 20m

$341
Quickest round-trip

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

mar. 8/4

11:38 am-5:23 pm

1 stop4h 45m

Key West

mié. 8/12

7:00 am-10:13 am

1 stop4h 13m

$347

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

mar. 8/4

7:46 am-1:29 pm

1 stop4h 43m

Key West

sáb. 8/8

2:24 pm-6:50 pm

1 stop5h 26m

$351

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

mar. 8/4

6:00 am-1:29 pm

1 stop6h 29m

Key West

jue. 8/13

2:35 pm-7:37 pm

1 stop6h 02m

$357

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

jue. 8/6

2:43 pm-7:51 pm

1 stop4h 08m

Key West

sáb. 8/8

6:18 pm-10:58 pm

1 stop5h 40m

$361

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

jue. 8/6

2:43 pm-7:51 pm

1 stop4h 08m

Key West

dom. 8/9

6:18 pm-11:37 pm

1 stop6h 19m

$367

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

mié. 5/20

2:50 pm-7:49 pm

1 stop3h 59m

Key West

jue. 5/28

11:48 am-5:56 pm

1 stop7h 08m

$377

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

mié. 5/20

11:49 am-5:23 pm

1 stop4h 34m

Key West

lun. 5/25

7:30 am-12:50 pm

1 stop6h 20m

$387

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

vie. 5/22

1:50 pm-7:49 pm

1 stop4h 59m

Key West

vie. 5/29

7:30 am-10:53 am

1 stop4h 23m

$403

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

mar. 5/12

1:50 pm-7:49 pm

1 stop4h 59m

Key West

mar. 5/19

6:19 pm-11:01 pm

1 stop5h 42m

$407

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Key West from

How to get the cheapest flight ticket from Panama City, Florida to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City, Florida and Key West?

What is the cheapest month to fly to Key West?

In general, February is the cheapest month to fly from Panama City, Florida to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $332. If you are unable to visit Key West during the month of February, then departing from Panama City, Florida during the month October is also very affordable. Most momondo users find prices during this month for around $346.

When to book flights from Panama City, Florida to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Key West (ECP to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Key West

Fastest flight time

3h 58m

Direct flights

None
The fastest flight from Panama City, Florida to Key West takes 3h 58m
There are no direct flights from Panama City, Florida to Key West. There are no popular flight routes from Panama City, Florida to Key West.
Search flight deals

Frequently asked questions about flying from Panama City, Florida to Key West

  • How far is Panama City NW Florida Beaches to Key West by plane?

    Panama City NW Florida Beaches and Key West are 453.5 mi apart from one another. 3h 58m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Key West Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Key West Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Key West Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Key West Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City NW Florida Beaches Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to Key West?

Best airlines flying from Panama City, Florida to Key West

Compare and see reviews for airlines that fly from Panama City, Florida to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $296Free CancellationRating
7.1
11,681 reviews
Search American Airlines flights
DeltaPriceFrom $306Free CancellationRating
7.9
8,463 reviews
Search Delta flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Key West?

It is quick and easy to find Panama City to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Panama City to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Key West?

Once all potential Panama City to Key West flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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