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Cheap flights from Palm Springs to Des Moines from $169

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Palm Springs to Des Moines departing on 3/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Palm Springs to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:05 pm - 11:59 pm
PSP
-
DSM
4h 54m
1 stop
American Airlines Logo
5:15 am - 11:45 am
DSM
-
PSP
8h 30m
1 stop
$351American Airlines
Wed, Mar 25 - Wed, Apr 1
American Airlines Logo
2:57 pm - 11:42 pm
PSP
-
DSM
6h 45m
1 stop
American Airlines Logo
5:05 am - 10:01 am
DSM
-
PSP
6h 56m
1 stop
$355American Airlines
Wed, Mar 25 - Wed, Apr 1
American Airlines Logo
6:01 am - 4:31 pm
PSP
-
DSM
8h 30m
1 stop
American Airlines Logo
2:38 pm - 6:07 pm
DSM
-
PSP
5h 29m
1 stop
$357American Airlines
Thu, Apr 16 - Mon, Apr 27
American Airlines Logo
9:34 pm - 10:26 am
PSP
-
DSM
10h 52m
2 stops
American Airlines Logo
5:30 am - 9:05 am
DSM
-
PSP
5h 35m
1 stop
$362American Airlines
Thu, Apr 16 - Mon, Apr 27
American Airlines Logo
2:57 pm - 11:42 pm
PSP
-
DSM
6h 45m
1 stop
American Airlines Logo
2:28 pm - 6:16 pm
DSM
-
PSP
5h 48m
1 stop
$368American Airlines
Wed, Mar 25 - Wed, Apr 1
American Airlines Logo
2:57 pm - 11:42 pm
PSP
-
DSM
6h 45m
1 stop
American Airlines Logo
5:05 am - 10:01 am
DSM
-
PSP
6h 56m
1 stop
$374American Airlines
Wed, Mar 25 - Wed, Apr 1
American Airlines Logo
6:01 am - 4:31 pm
PSP
-
DSM
8h 30m
1 stop
American Airlines Logo
6:26 pm - 9:38 pm
DSM
-
PSP
5h 12m
1 stop
$377American Airlines
Thu, Apr 16 - Mon, Apr 27
Southwest Logo
5:25 am - 3:40 pm
PSP
-
DSM
8h 15m
2 stops
Southwest Logo
7:15 pm - 10:20 pm
DSM
-
PSP
5h 05m
1 stop
$382Southwest
Thu, Mar 26 - Mon, Mar 30
American Airlines Logo
9:34 pm - 10:26 am
PSP
-
DSM
10h 52m
2 stops
American Airlines Logo
11:09 am - 6:07 pm
DSM
-
PSP
8h 58m
2 stops
$384American Airlines
Thu, Apr 16 - Mon, Apr 27
American Airlines Logo
9:34 pm - 10:26 am
PSP
-
DSM
10h 52m
2 stops
American Airlines Logo
11:09 am - 6:07 pm
DSM
-
PSP
8h 58m
2 stops
$387American Airlines
Thu, Apr 16 - Mon, Apr 27

American Airlines flights from Palm Springs to Des Moines

Our best American Airlines deals on Palm Springs to Des Moines flight tickets
American Airlines
Mar 25
PSP5:05 pmPalm Springs
4h 54m
1 stop
DSM11:59 pmDes Moines
Apr 1
DSM5:15 amDes Moines
8h 30m
1 stop
PSP11:45 amPalm Springs
$351
American Airlines
Mar 25
PSP2:57 pmPalm Springs
6h 45m
1 stop
DSM11:42 pmDes Moines
Apr 1
DSM5:05 amDes Moines
6h 56m
1 stop
PSP10:01 amPalm Springs
$355
American Airlines
Apr 16
PSP6:01 amPalm Springs
8h 30m
1 stop
DSM4:31 pmDes Moines
Apr 27
DSM2:38 pmDes Moines
5h 29m
1 stop
PSP6:07 pmPalm Springs
$357

United Airlines flights from Palm Springs to Des Moines

Our best United Airlines deals on Palm Springs to Des Moines flight tickets
United Airlines
Mar 25
PSP4:27 pmPalm Springs
5h 15m
1 stop
DSM11:42 pmDes Moines
Mar 31
DSM5:30 amDes Moines
6h 02m
1 stop
PSP9:32 amPalm Springs
$417
United Airlines
Mar 25
PSP4:27 pmPalm Springs
5h 15m
1 stop
DSM11:42 pmDes Moines
Mar 31
DSM5:30 amDes Moines
10h 42m
2 stops
PSP2:12 pmPalm Springs
$422
United Airlines
Mar 25
PSP4:27 pmPalm Springs
5h 15m
1 stop
DSM11:42 pmDes Moines
Mar 29
DSM3:21 pmDes Moines
9h 14m
1 stop
PSP10:35 pmPalm Springs
$462

momondo Fare Finder

 
Customize your flight search to find flights from Palm Springs to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 21, 2026.
Use the filters below to find and compare flights from Palm Springs to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Palm SpringsDes Moines

PSP - DSM

PSPDSM

Palm Springs

Wed 3/25

5:05 pm-11:59 pm

1 stop4h 54m

Des Moines

Wed 4/1

5:15 am-11:45 am

1 stop8h 30m

$351

Palm SpringsDes Moines

PSP - DSM

PSPDSM

Palm Springs

Wed 3/25

2:57 pm-11:42 pm

1 stop6h 45m

Des Moines

Wed 4/1

5:05 am-10:01 am

1 stop6h 56m

$355

Palm SpringsDes Moines

PSP - DSM

PSPDSM

Palm Springs

Thu 4/16

6:01 am-4:31 pm

1 stop8h 30m

Des Moines

Mon 4/27

2:38 pm-6:07 pm

1 stop5h 29m

$357

Palm SpringsDes Moines

PSP - DSM

PSPDSM

Palm Springs

Thu 4/16

9:34 pm-10:26 am

2 stops10h 52m

Des Moines

Mon 4/27

5:30 am-9:05 am

1 stop5h 35m

$362

Palm SpringsDes Moines

PSP - DSM

PSPDSM

Palm Springs

Wed 3/25

2:57 pm-11:42 pm

1 stop6h 45m

Des Moines

Wed 4/1

2:28 pm-6:16 pm

1 stop5h 48m

$368

Palm SpringsDes Moines

PSP - DSM

PSPDSM

Palm Springs

Wed 3/25

2:57 pm-11:42 pm

1 stop6h 45m

Des Moines

Wed 4/1

5:05 am-10:01 am

1 stop6h 56m

$374

Palm SpringsDes Moines

PSP - DSM

PSPDSM

Palm Springs

Thu 4/16

6:01 am-4:31 pm

1 stop8h 30m

Des Moines

Mon 4/27

6:26 pm-9:38 pm

1 stop5h 12m

$377

Palm SpringsDes Moines

PSP - DSM

PSPDSM

Palm Springs

Thu 3/26

5:25 am-3:40 pm

2 stops8h 15m

Des Moines

Mon 3/30

7:15 pm-10:20 pm

1 stop5h 05m

$382

Palm SpringsDes Moines

PSP - DSM

PSPDSM

Palm Springs

Thu 4/16

9:34 pm-10:26 am

2 stops10h 52m

Des Moines

Mon 4/27

11:09 am-6:07 pm

2 stops8h 58m

$384

Palm SpringsDes Moines

PSP - DSM

PSPDSM

Palm Springs

Thu 4/16

9:34 pm-10:26 am

2 stops10h 52m

Des Moines

Mon 4/27

11:09 am-6:07 pm

2 stops8h 58m

$387

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Palm Springs to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Palm Springs to Des Moines?

American Airlines and Southwest are the most popular carriers operating from Palm Springs to Des Moines

What airlines fly to Des Moines?

American Airlines, Allegiant Air and United Airlines are the top three most popular airlines that fly to Des Moines from Palm Springs according to our data. American Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 6 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When to book flights from Palm Springs to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Palm Springs to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Palm Springs to Des Moines (PSP to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Palm Springs to Des Moines

Fastest flight time

5h 05m

Direct flights

None
The fastest flight from Palm Springs to Des Moines takes 5h 05m
There are no direct flights from Palm Springs to Des Moines. There are no popular flight routes from Palm Springs to Des Moines.
Search flight deals

  • How far is Palm Springs to Des Moines by plane?

    Des Moines is 1356.2 mi away from Palm Springs. In terms of flight time, this usually takes a little over 5h 05m.

  • When did momondo last update prices for flights from Palm Springs Airport to Des Moines Airport?

    Prices for flights from Palm Springs Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Palm Springs Airport to Des Moines Airport?

  • How old do you have to be to fly from Palm Springs Airport to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Palm Springs Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Palm Springs to Des Moines?

Best airlines flying from Palm Springs to Des Moines

Compare and see reviews for airlines that fly from Palm Springs to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $316Free CancellationRating
7.4
9,335 reviews
Search United Airlines flights
American AirlinesPriceFrom $323Free CancellationRating
7.2
11,334 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Newton
Johnston
Boone
Osceola
Norwalk
Oskaloosa
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Palm Springs to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Palm Springs to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from Palm Springs to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Palm Springs on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Palm Springs to Des Moines?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Palm Springs to Des Moines.

I’m not ready to book a flight from Palm Springs to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Palm Springs to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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