Cheap flights from Orlando to St. Louis from $40

In general, February is the cheapest month to fly from Orlando to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $126. The month of December is another great option to travel to St. Louis, with average flight prices from Orlando averaging around $173.

The cheapest day to depart on your flight to St. Louis is on a Friday when prices can be found for as low as $256. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $481. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

Flying to St. Louis from Orlando in the evening is the least expensive time of day to depart. momondo users have found prices as low as $225 when looking at flights departing in the evening. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $435 per ticket.

Fly from Orlando to Lambert-St Louis for the best Orlando - Lambert-St Louis flight prices

You are more likely to see cheaper flights to St. Louis from Orlando when booking weeks ahead of your departure date. In general, you can expect to find flights to St. Louis for around $304 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to St. Louis from Orlando for as low as $214 on momondo.

There are 3 cabin classes available to choose from on Orlando to St. Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier, American Airlines, and Delta are the most popular carriers operating from Orlando to Lambert-St Louis

Frontier, Southwest and Allegiant Air are the top three most popular airlines that fly to St. Louis from Orlando according to our data. Frontier is the first choice among our users, with 52% of people opting to fly with this airline when traveling to St. Louis. Keep in mind that there are 5 different airlines that fly to St. Louis on a routine basis, so you have a few additional options to choose from.

As of September 2026, 1 flights take off from Orlando and land in St. Louis each day. The most common flight departure time for this route is 1:00PM, with 44% of daily flights taking off in the afternoon.

10 flights are operational weekly from Orlando to St. Louis as of September 2026. The most popular departure day for this route is Tue, with 50% of flights per week taking off on this day.