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Cheap flights from Ohio to Florence from $303

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Florence departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Ohio to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:00 am - 5:50 pm
PIT
-
FLO
9h 50m
2 stops
American Airlines Logo
6:20 pm - 7:30 am
FLO
-
PIT
13h 10m
2 stops
$367American Airlines
Mon, Mar 2 - Mon, Mar 9
American Airlines Logo
8:00 am - 5:21 pm
PIT
-
FLO
9h 21m
2 stops
American Airlines Logo
5:16 am - 7:13 pm
FLO
-
PIT
13h 57m
2 stops
$427American Airlines
Tue, Feb 17 - Sat, Feb 21
American Airlines Logo
1:29 pm - 11:57 pm
PIT
-
FLO
10h 28m
2 stops
American Airlines Logo
6:20 pm - 7:30 am
FLO
-
PIT
13h 10m
2 stops
$455American Airlines
Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
10:33 am - 11:08 pm
CLE
-
FLO
12h 35m
2 stops
American Airlines Logo
5:16 am - 3:27 pm
FLO
-
CLE
10h 11m
2 stops
$467American Airlines
Tue, Feb 17 - Sat, Feb 21
American Airlines Logo
6:49 am - 5:21 pm
CLE
-
FLO
10h 32m
2 stops
American Airlines Logo
5:16 am - 9:04 am
FLO
-
CLE
3h 48m
1 stop
$478American Airlines
Tue, Feb 17 - Sat, Feb 21
American Airlines Logo
4:45 pm - 11:08 pm
PIT
-
FLO
6h 23m
1 stop
American Airlines Logo
5:16 am - 9:06 am
FLO
-
PIT
3h 50m
1 stop
$489American Airlines
Tue, Feb 17 - Sat, Feb 21
American Airlines Logo
4:45 pm - 11:08 pm
PIT
-
FLO
6h 23m
1 stop
American Airlines Logo
5:16 am - 3:09 pm
FLO
-
PIT
9h 53m
2 stops
$494American Airlines
Tue, Feb 17 - Sat, Feb 21
American Airlines Logo
10:05 am - 3:50 pm
CLE
-
FLO
5h 45m
1 stop
American Airlines Logo
5:24 am - 9:15 am
FLO
-
CLE
3h 51m
1 stop
$495American Airlines
Thu, Apr 9 - Sun, Apr 12
American Airlines Logo
7:42 am - 3:50 pm
CLE
-
FLO
8h 08m
2 stops
American Airlines Logo
5:24 am - 9:15 am
FLO
-
CLE
3h 51m
1 stop
$500American Airlines
Thu, Apr 9 - Sun, Apr 12
American Airlines Logo
6:41 pm - 11:08 pm
CAK
-
FLO
4h 27m
1 stop
American Airlines Logo
6:25 pm - 10:56 pm
FLO
-
CAK
4h 31m
1 stop
$501American Airlines
Tue, Feb 17 - Sat, Feb 21

American Airlines flights from Ohio to Florence, South Carolina

Our best American Airlines deals on Ohio to Florence, South Carolina flight tickets
American Airlines
Mar 2
PIT8:00 amPittsburgh
9h 50m
2 stops
FLO5:50 pmFlorence
Mar 9
FLO6:20 pmFlorence
13h 10m
2 stops
PIT7:30 amPittsburgh
$367
American Airlines
Feb 17
PIT8:00 amPittsburgh
9h 21m
2 stops
FLO5:21 pmFlorence
Feb 21
FLO5:16 amFlorence
13h 57m
2 stops
PIT7:13 pmPittsburgh
$427
American Airlines
Mar 19
PIT1:29 pmPittsburgh
10h 28m
2 stops
FLO11:57 pmFlorence
Mar 26
FLO6:20 pmFlorence
13h 10m
2 stops
PIT7:30 amPittsburgh
$455

momondo Fare Finder

 
Customize your flight search to find flights from Ohio to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Ohio to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Mon 3/2

8:00 am-5:50 pm

2 stops9h 50m

Florence

Mon 3/9

6:20 pm-7:30 am

2 stops13h 10m

$367

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Tue 2/17

8:00 am-5:21 pm

2 stops9h 21m

Florence

Sat 2/21

5:16 am-7:13 pm

2 stops13h 57m

$427

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Thu 3/19

1:29 pm-11:57 pm

2 stops10h 28m

Florence

Thu 3/26

6:20 pm-7:30 am

2 stops13h 10m

$455

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 2/17

10:33 am-11:08 pm

2 stops12h 35m

Florence

Sat 2/21

5:16 am-3:27 pm

2 stops10h 11m

$467

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Tue 2/17

6:49 am-5:21 pm

2 stops10h 32m

Florence

Sat 2/21

5:16 am-9:04 am

1 stop3h 48m

$478

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Tue 2/17

4:45 pm-11:08 pm

1 stop6h 23m

Florence

Sat 2/21

5:16 am-9:06 am

1 stop3h 50m

$489

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Tue 2/17

4:45 pm-11:08 pm

1 stop6h 23m

Florence

Sat 2/21

5:16 am-3:09 pm

2 stops9h 53m

$494

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Thu 4/9

10:05 am-3:50 pm

1 stop5h 45m

Florence

Sun 4/12

5:24 am-9:15 am

1 stop3h 51m

$495

ClevelandFlorence

CLE - FLO

CLEFLO

Cleveland Hopkins Intl

Thu 4/9

7:42 am-3:50 pm

2 stops8h 08m

Florence

Sun 4/12

5:24 am-9:15 am

1 stop3h 51m

$500

AkronFlorence

CAK - FLO

CAKFLO

Akron/Canton

Tue 2/17

6:41 pm-11:08 pm

1 stop4h 27m

Florence

Sat 2/21

6:25 pm-10:56 pm

1 stop4h 31m

$501

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Ohio to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Ohio to Florence?

American Airlines is the most popular carrier operating from Ohio to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Breeze Airways and Allegiant Air are the top three most popular airlines that fly to Florence, South Carolina from Ohio according to our data. American Airlines is the first choice among our users, with 38% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Ohio to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Florence, South Carolina

Fastest flight time

3h 54m

Direct flights

None
The fastest flight from Ohio to Florence, South Carolina takes 3h 54m
There are no direct flights from Ohio to Florence, South Carolina. There are no popular flight routes from Ohio to Florence, South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Ohio to Florence Airport?

    Prices for flights from Ohio to Florence Airport refresh daily.

  • How many operators does momondo search for flights from Ohio to Florence Airport?

  • How old do you have to be to fly from Ohio to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Ohio to Florence, South Carolina

Compare and see reviews for airlines that fly from Ohio to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $377Free CancellationRating
7.2
11,216 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Florence?

Finding the right flight to Florence from Ohio is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florence quick and easy, saving you time and money.

Can I find flights from Ohio to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Ohio which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Ohio to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Ohio.

I’m not ready to book a flight from Ohio to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Ohio to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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