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Cheap flights from Chicago O'Hare Intl Airport to Missouri from $49

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Missouri departing on 5/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to Missouri

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:42 pm - 9:07 pm
ORD
-
STL
1h 25mnonstop
United Airlines Logo
7:40 am - 9:09 am
STL
-
ORD
1h 29mnonstop
$97United Airlines
Tue, Mar 10 - Tue, Mar 17
American Airlines Logo
7:18 am - 8:41 am
ORD
-
STL
1h 23mnonstop
American Airlines Logo
6:00 am - 7:28 am
STL
-
ORD
1h 28mnonstop
$98American Airlines
Thu, Mar 5 - Sun, Mar 8
Southwest Logo
4:15 pm - 9:25 pm
ORD
-
STL
5h 10m
1 stop
Southwest Logo
7:30 am - 12:50 pm
STL
-
ORD
5h 20m
1 stop
$117Southwest
Tue, Mar 10 - Wed, Mar 11
Contour Logo
11:50 am - 1:25 pm
ORD
-
CGI
1h 35mnonstop
Contour Logo
9:25 am - 11:10 am
CGI
-
ORD
1h 45mnonstop
$122Contour
Wed, Feb 25 - Sun, Mar 1
Contour Logo
11:50 am - 1:30 pm
ORD
-
CGI
1h 40mnonstop
Contour Logo
9:25 am - 11:10 am
CGI
-
ORD
1h 45mnonstop
$126Contour
Fri, Mar 6 - Sun, Mar 8
United Airlines Logo
8:15 pm - 9:47 pm
ORD
-
STL
1h 32mnonstop
United Airlines Logo
7:45 am - 9:11 am
STL
-
ORD
1h 26mnonstop
$134United Airlines
Wed, Apr 1 - Thu, Apr 2
American Airlines Logo
10:23 am - 11:45 am
ORD
-
STL
1h 22mnonstop
American Airlines Logo
7:05 am - 8:36 am
STL
-
ORD
1h 31mnonstop
$136American Airlines
Thu, May 7 - Wed, May 13
Contour Logo
11:50 am - 1:25 pm
ORD
-
CGI
1h 35mnonstop
Contour Logo
9:25 am - 11:10 am
CGI
-
ORD
1h 45mnonstop
$139Contour
Wed, Feb 25 - Sun, Mar 1
Frontier Logo
5:05 am - 11:49 am
ORD
-
STL
6h 44m
1 stop
Frontier Logo
2:09 pm - 8:23 am
STL
-
ORD
18h 14m
1 stop
$146Frontier
Fri, Mar 6 - Mon, Mar 9
Southwest Logo
4:15 pm - 9:25 pm
ORD
-
STL
5h 10m
1 stop
Southwest Logo
7:30 am - 12:50 pm
STL
-
ORD
5h 20m
1 stop
$154Southwest
Wed, Mar 11 - Wed, Mar 18

Frontier flights from Chicago O'Hare Intl Airport to Missouri

Our best Frontier deals on Chicago O'Hare Intl Airport to Missouri flight tickets
Frontier
Mar 6
ORD5:05 amChicago O'Hare Intl
6h 44m
1 stop
STL11:49 amLambert-St Louis
Mar 9
STL2:09 pmLambert-St Louis
18h 14m
1 stop
ORD8:23 amChicago O'Hare Intl
$146
Frontier
May 7
ORD5:01 amChicago O'Hare Intl
5h 29m
1 stop
STL10:30 amLambert-St Louis
May 9
STL8:12 pmLambert-St Louis
13h 38m
1 stop
ORD9:50 amChicago O'Hare Intl
$160
Frontier
Mar 13
ORD5:01 amChicago O'Hare Intl
8h 33m
1 stop
STL1:34 pmLambert-St Louis
Mar 23
STL12:16 pmLambert-St Louis
20h 07m
1 stop
ORD8:23 amChicago O'Hare Intl
$164

Delta flights from Chicago O'Hare Intl Airport to Missouri

Our best Delta deals on Chicago O'Hare Intl Airport to Missouri flight tickets
Delta
Apr 14
ORD7:00 amChicago O'Hare Intl
9h 50m
2 stops
STL4:50 pmLambert-St Louis
Apr 21
STL6:48 amLambert-St Louis
5h 57m
1 stop
ORD12:45 pmChicago O'Hare Intl
$162
Delta
May 16
ORD12:30 pmChicago O'Hare Intl
4h 19m
1 stop
STL4:49 pmLambert-St Louis
May 18
STL7:09 pmLambert-St Louis
4h 50m
1 stop
ORD11:59 pmChicago O'Hare Intl
$201
Delta
May 7
ORD7:00 amChicago O'Hare Intl
6h 05m
1 stop
STL1:05 pmLambert-St Louis
May 9
STL6:20 amLambert-St Louis
6h 36m
2 stops
ORD12:56 pmChicago O'Hare Intl
$206

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Tue 3/10

7:42 pm-9:07 pm

Nonstop1h 25m

Lambert-St Louis

Tue 3/17

7:40 am-9:09 am

Nonstop1h 29m

$97

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Thu 3/5

7:18 am-8:41 am

Nonstop1h 23m

Lambert-St Louis

Sun 3/8

6:00 am-7:28 am

Nonstop1h 28m

$98

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Tue 3/10

4:15 pm-9:25 pm

1 stop5h 10m

Lambert-St Louis

Wed 3/11

7:30 am-12:50 pm

1 stop5h 20m

$117

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Wed 2/25

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Sun 3/1

9:25 am-11:10 am

Nonstop1h 45m

$122

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Fri 3/6

11:50 am-1:30 pm

Nonstop1h 40m

Cape Girardeau

Sun 3/8

9:25 am-11:10 am

Nonstop1h 45m

$126

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Wed 4/1

8:15 pm-9:47 pm

Nonstop1h 32m

Lambert-St Louis

Thu 4/2

7:45 am-9:11 am

Nonstop1h 26m

$134

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Thu 5/7

10:23 am-11:45 am

Nonstop1h 22m

Lambert-St Louis

Wed 5/13

7:05 am-8:36 am

Nonstop1h 31m

$136

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Wed 2/25

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Sun 3/1

9:25 am-11:10 am

Nonstop1h 45m

$139

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Fri 3/6

5:05 am-11:49 am

1 stop6h 44m

Lambert-St Louis

Mon 3/9

2:09 pm-8:23 am

1 stop18h 14m

$146

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Wed 3/11

4:15 pm-9:25 pm

1 stop5h 10m

Lambert-St Louis

Wed 3/18

7:30 am-12:50 pm

1 stop5h 20m

$154

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Missouri from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

In general, December is the cheapest month to fly from Chicago O'Hare Intl Airport to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $213. If you aren’t able to travel to Missouri during the month of December, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $217.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Chicago O'Hare Intl Airport to Missouri is on a Wednesday when prices can be found for as low as $287. Flights from Chicago O'Hare Intl Airport to Missouri on a Tuesday will generally be more expensive and average around $491. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is at noon. momondo users have found flights departing from Chicago O'Hare Intl Airport to Missouri at noon for as low as $317. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the afternoon, with an average ticket price of $477. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Chicago O'Hare Intl to Missouri flight route?

Fly from Chicago O'Hare Intl to Fort Leonard Wood Waynesville Regional for the best Chicago O'Hare Intl - Missouri flight prices

How far in advance should I book a flight to Missouri?

You are more likely to see cheaper flights to Missouri from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $315 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from Chicago O'Hare Intl Airport for as low as $165 on momondo.

What cabin class options are available on Chicago O'Hare Intl to Missouri flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Missouri flights?

No. A direct flight is the cheapest option for a flight between Chicago O'Hare Intl Airport to Missouri.

Cheap Chicago O'Hare Intl Airport to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Missouri

Best Price Found

$86

Fastest flight time

1h 23m

Direct flights

Every day

Airports in Missouri

55 airports
The best one-way flight to Missouri from Chicago O'Hare Intl Airport in the past 72 hours is $86. The best round-trip flight deal from Chicago O'Hare Intl Airport to Missouri found on momondo in the last 72 hours is $118.
The fastest flight from Chicago O'Hare Intl Airport to Missouri takes 1h 23m
Direct flights go from Chicago O'Hare Intl Airport to Missouri every day.
There are 55 airports in Missouri. From Chicago O'Hare Intl Airport there are direct flights to Lambert-St Louis (STL).
Search flight deals

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Missouri?

    Prices for flights from Chicago O'Hare Intl Airport to Missouri are updated daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Missouri?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Missouri?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago O'Hare Intl Airport to Missouri.

  • What documentation or ID do you need to fly to Missouri?

    The travel and health documents you'll need for your trip to Missouri may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Missouri. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Missouri?

Best airlines flying from Chicago O'Hare Intl Airport to Missouri

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Missouri with momondo
Airline
Rating
Free Cancellation
Price
ContourPriceFrom $108Free CancellationRating
7.6
42 reviews
Search Contour flights
American AirlinesPriceFrom $121Free CancellationRating
7.2
11,287 reviews
Search American Airlines flights
United AirlinesPriceFrom $144Free CancellationRating
7.4
9,288 reviews
Search United Airlines flights
Southern / MokulelePriceFrom $156Free CancellationRating
0.0
0 reviews
Search Southern / Mokulele flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Missouri?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to Missouri. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to Missouri with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to Missouri flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to Missouri?

momondo helps you find the best flight between Chicago and Missouri by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Missouri right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Missouri flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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