Cheap flights from Chicago O'Hare Intl Airport to Missouri from $59
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Missouri departing on 12/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
ChicagoKirksville
ORD Chicago O'Hare Intl - IRK Kirksville Cannon Memorial
ORDIRK
Chicago O'Hare Intl
Sat 10/24
2:55 pm-4:25 pm
Nonstop1h 30m
Kirksville Cannon Memorial
Wed 10/28
12:30 pm-2:15 pm
Nonstop1h 45m
ChicagoKirksville
ORD Chicago O'Hare Intl - IRK Kirksville Cannon Memorial
ORDIRK
Chicago O'Hare Intl
Thu 10/29
2:55 pm-4:25 pm
Nonstop1h 30m
Kirksville Cannon Memorial
Thu 11/5
12:30 pm-2:15 pm
Nonstop1h 45m
ChicagoKirksville
ORD Chicago O'Hare Intl - IRK Kirksville Cannon Memorial
ORDIRK
Chicago O'Hare Intl
Thu 11/12
2:55 pm-4:25 pm
Nonstop1h 30m
Kirksville Cannon Memorial
Tue 11/17
12:30 pm-2:15 pm
Nonstop1h 45m
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Sat 11/21
9:59 am-4:41 pm
1 stop6h 42m
Lambert-St Louis
Sun 11/22
6:40 am-10:39 am
1 stop3h 59m
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Wed 10/28
6:30 am-3:23 pm
1 stop8h 53m
Lambert-St Louis
Fri 10/30
7:59 pm-6:16 pm
2 stops22h 17m
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Sat 11/21
9:59 am-4:41 pm
1 stop6h 42m
Lambert-St Louis
Sun 11/22
6:40 am-10:39 am
1 stop3h 59m
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Fri 11/6
2:12 pm-3:43 pm
Nonstop1h 31m
Lambert-St Louis
Sun 11/8
7:30 am-9:00 am
Nonstop1h 30m
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Fri 11/6
6:03 pm-7:22 pm
Nonstop1h 19m
Lambert-St Louis
Sun 11/8
8:15 pm-9:51 pm
Nonstop1h 36m
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Thu 12/3
6:30 pm-7:58 pm
Nonstop1h 28m
Lambert-St Louis
Sun 12/6
1:43 pm-3:24 pm
Nonstop1h 41m
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Tue 12/8
9:45 pm-10:59 pm
Nonstop1h 14m
Lambert-St Louis
Wed 12/9
5:25 am-6:58 am
Nonstop1h 33m
See travel insights to Missouri from
How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Missouri
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Missouri?
In general, December is the cheapest month to fly from Chicago O'Hare Intl Airport to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $324. If you aren’t able to travel to Missouri during the month of December, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $346.
What is the cheapest day to depart on your flight to Missouri?
The cheapest day to depart from Chicago O'Hare Intl Airport to Missouri is on a Saturday when prices can be found for as low as $262. Flights from Chicago O'Hare Intl Airport to Missouri on a Monday will generally be more expensive and average around $543. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.
What is the cheapest time of day to depart on your flight to Missouri?
According to our data, the cheapest time of day to fly to Missouri is at noon. momondo users have found flights departing from Chicago O'Hare Intl Airport to Missouri at noon for as low as $383. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the afternoon, with an average ticket price of $517. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.
What is the cheapest Chicago O'Hare Intl to Missouri flight route?
Fly from Chicago O'Hare Intl to Lambert-St Louis for the best Chicago O'Hare Intl - Missouri flight prices
What cabin class options are available on Chicago O'Hare Intl Airport to Missouri flights?
There are 4 cabin classes available to choose from on Chicago O'Hare Intl Airport to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
Can stopping save me money on Chicago O'Hare Intl Airport to Missouri flights?
No. A direct flight is the cheapest option for a flight between Chicago O'Hare Intl Airport to Missouri.
What is the cheapest airline that flies from Chicago O'Hare Intl to Missouri?
United Airlines, Delta, and Contour are the most popular carriers operating from Chicago O'Hare Intl to Missouri
What airlines fly to Missouri?
United Airlines, American Airlines and Contour are the top three most popular airlines that fly to Missouri from Chicago O'Hare Intl Airport according to our data. United Airlines is the first choice among our users, with 64% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 3 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.
How many flights depart from Chicago O'Hare Intl Airport to Missouri on average per day?
The number of flights available between Chicago O'Hare Intl Airport and Missouri is 132 per day as of October 2026. The most frequent departure time is 9:00PM, with 42% of daily flights leaving in the afternoon.
How many flights depart from Chicago O'Hare Intl Airport to Missouri on average per week?
As of October 2026, 925 flights take off from Chicago O'Hare Intl Airport and land in Missouri each week. The most common flight departure day for this route is Sat, with 17% of weekly flights taking off on this day.
Cheap Chicago O'Hare Intl Airport to Missouri flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Missouri
Frequently asked questions about flying from Chicago O'Hare Intl Airport to Missouri
When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Missouri?
Prices for flights from Chicago O'Hare Intl Airport to Missouri are updated daily.
How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Missouri?
There are 3 operators available for flights from Chicago O'Hare Intl Airport to Missouri as of October 2026.
How old do you have to be to fly from Chicago O'Hare Intl Airport to Missouri?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago O'Hare Intl Airport to Missouri.
What documentation or ID do you need to fly to Missouri?
The travel and health documents you'll need for your trip to Missouri may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Missouri. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Chicago O'Hare Intl Airport to Missouri?
Based on momondo bookings for flights between Chicago O'Hare Intl Airport and Missouri, the leading plane model is Airbus A319, making up 12.89% of the total bookings. Other popular models include Boeing 737-800 with 12.20%, Embraer 175 (Enhanced Winglets) with 10.46%, and Canadair (Bombardier) Regional Jet CRJ-550 with 9.74%.
Best airlines flying from Chicago O'Hare Intl Airport to Missouri
Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Missouri with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $104 | Free Cancellation | Rating 7.5 43 reviews | |||
| PriceFrom $151 | Free Cancellation | Rating 7.0 12,151 reviews | |||
| PriceFrom $172 | Free Cancellation | Rating 7.4 10,334 reviews |
Why use momondo?
Why should I use momondo to find a flight deal from Chicago to Missouri?
momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to Missouri. momondo saves you time and could save you money on your trip.
Can I find flights from Chicago to Missouri with flexible booking policies on momondo?
Yes. momondo allows you to filter the results for Chicago to Missouri flights to just show those with flexible booking policies.
How can momondo help me find flights from Chicago to Missouri?
momondo helps you find the best flight between Chicago and Missouri by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.
I’m not ready to book a flight from Chicago to Missouri right now. Can momondo alert me if prices change?
Of course. momondo tracks the price of Chicago to Missouri flights. All you need is a valid email address and we will do the rest; it is that quick and easy.