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Cheap flights from Myrtle Beach to Indianapolis from $87

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Indianapolis departing on 2/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
9:09 am - 7:23 pm
MYR
-
IND
10h 14m1 stop
Spirit Airlines Logo
6:00 am - 2:55 pm
IND
-
MYR
8h 55m1 stop
$173Spirit Airlines
Tue, Feb 17 - Fri, Feb 27
Spirit Airlines Logo
9:09 am - 7:23 pm
MYR
-
IND
10h 14m1 stop
Spirit Airlines Logo
6:00 am - 2:55 pm
IND
-
MYR
8h 55m1 stop
$174Spirit Airlines
Thu, Feb 26 - Sun, Mar 1
Multiple Airlines Logo
9:54 pm - 8:28 pm
MYR
-
IND
22h 34m2 stops
Multiple Airlines Logo
8:18 pm - 8:13 am
IND
-
MYR
11h 55m1 stop
$215Multiple Airlines
Tue, Feb 17 - Fri, Feb 27
Spirit Airlines Logo
9:09 am - 8:32 am
MYR
-
IND
23h 23m2 stops
Spirit Airlines Logo
8:18 pm - 8:13 am
IND
-
MYR
11h 55m1 stop
$220Spirit Airlines
Tue, Feb 17 - Fri, Feb 27
Multiple Airlines Logo
9:09 am - 7:23 pm
MYR
-
IND
10h 14m1 stop
Multiple Airlines Logo
9:57 pm - 8:13 am
IND
-
MYR
34h 16m2 stops
$221Multiple Airlines
Thu, Feb 26 - Sun, Mar 1
Spirit Airlines Logo
10:00 am - 12:18 am
MYR
-
IND
14h 18m1 stop
Spirit Airlines Logo
6:55 am - 2:42 pm
IND
-
MYR
7h 47m1 stop
$222Spirit Airlines
Thu, Jan 22 - Mon, Jan 26
Multiple Airlines Logo
4:01 pm - 11:43 am
MYR
-
IND
19h 42m2 stops
Multiple Airlines Logo
7:33 pm - 12:12 pm
IND
-
MYR
16h 39m1 stop
$229Multiple Airlines
Thu, Jan 22 - Mon, Jan 26
Multiple Airlines Logo
3:17 pm - 10:38 pm
MYR
-
IND
7h 21m1 stop
Multiple Airlines Logo
6:15 am - 7:37 pm
IND
-
MYR
13h 22m1 stop
$252Multiple Airlines
Wed, May 6 - Wed, May 20
Spirit Airlines Logo
10:00 am - 9:43 am
MYR
-
IND
23h 43m3 stops
Spirit Airlines Logo
6:55 am - 2:42 pm
IND
-
MYR
7h 47m1 stop
$267Spirit Airlines
Thu, Jan 22 - Mon, Jan 26
American Airlines Logo
10:27 am - 2:54 pm
MYR
-
IND
4h 27m1 stop
American Airlines Logo
8:04 pm - 11:55 pm
IND
-
MYR
3h 51m1 stop
$271American Airlines
Thu, Feb 12 - Thu, Feb 12

Southwest flights from Myrtle Beach to Indianapolis

Our best Southwest deals on Myrtle Beach to Indianapolis flight tickets
Southwest
Jan 29
MYR8:15 amMyrtle Beach Intl
6h 50m
2 stops
IND3:05 pmIndianapolis
Feb 2
IND10:30 amIndianapolis
9h 15m
2 stops
MYR7:45 pmMyrtle Beach Intl
$282
Southwest
May 6
MYR2:10 pmMyrtle Beach Intl
6h 55m
2 stops
IND9:05 pmIndianapolis
May 20
IND6:40 amIndianapolis
6h 50m
2 stops
MYR1:30 pmMyrtle Beach Intl
$306
Southwest
Feb 26
MYR1:00 pmMyrtle Beach Intl
11h 05m
2 stops
IND12:05 amIndianapolis
Mar 1
IND6:55 amIndianapolis
11h 00m
2 stops
MYR5:55 pmMyrtle Beach Intl
$383

United Airlines flights from Myrtle Beach to Indianapolis

Our best United Airlines deals on Myrtle Beach to Indianapolis flight tickets
United Airlines
Feb 5
MYR1:25 pmMyrtle Beach Intl
7h 02m
1 stop
IND8:27 pmIndianapolis
Feb 9
IND6:00 amIndianapolis
6h 41m
1 stop
MYR12:41 pmMyrtle Beach Intl
$373
United Airlines
Feb 5
MYR1:25 pmMyrtle Beach Intl
7h 02m
1 stop
IND8:27 pmIndianapolis
Feb 9
IND6:00 amIndianapolis
6h 41m
1 stop
MYR12:41 pmMyrtle Beach Intl
$382
United Airlines
Feb 5
MYR1:25 pmMyrtle Beach Intl
10h 05m
2 stops
IND11:30 pmIndianapolis
Feb 9
IND6:00 amIndianapolis
6h 41m
1 stop
MYR12:41 pmMyrtle Beach Intl
$410

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Tue 2/17

9:09 am-7:23 pm

1 stop10h 14m

Indianapolis

Fri 2/27

6:00 am-2:55 pm

1 stop8h 55m

$173

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 2/26

9:09 am-7:23 pm

1 stop10h 14m

Indianapolis

Sun 3/1

6:00 am-2:55 pm

1 stop8h 55m

$174

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Tue 2/17

9:54 pm-8:28 pm

2 stops22h 34m

Indianapolis

Fri 2/27

8:18 pm-8:13 am

1 stop11h 55m

$215

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Tue 2/17

9:09 am-8:32 am

2 stops23h 23m

Indianapolis

Fri 2/27

8:18 pm-8:13 am

1 stop11h 55m

$220

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 2/26

9:09 am-7:23 pm

1 stop10h 14m

Indianapolis

Sun 3/1

9:57 pm-8:13 am

2 stops34h 16m

$221

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 1/22

10:00 am-12:18 am

1 stop14h 18m

Indianapolis

Mon 1/26

6:55 am-2:42 pm

1 stop7h 47m

$222

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 1/22

4:01 pm-11:43 am

2 stops19h 42m

Indianapolis

Mon 1/26

7:33 pm-12:12 pm

1 stop16h 39m

$229

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 5/6

3:17 pm-10:38 pm

1 stop7h 21m

Indianapolis

Wed 5/20

6:15 am-7:37 pm

1 stop13h 22m

$252

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 1/22

10:00 am-9:43 am

3 stops23h 43m

Indianapolis

Mon 1/26

6:55 am-2:42 pm

1 stop7h 47m

$267

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 2/12

10:27 am-2:54 pm

1 stop4h 27m

Indianapolis

Thu 2/12

8:04 pm-11:55 pm

1 stop3h 51m

$271

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Indianapolis from

How to get the cheapest flight ticket from Myrtle Beach to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Indianapolis?

In general, August is the cheapest month to fly from Myrtle Beach to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $184. If you are unable to visit Indianapolis during the month of August, then departing from Myrtle Beach during the month June is also very affordable. Most momondo users find prices during this month for around $231.

What is the cheapest Myrtle Beach Intl to Indianapolis flight route?

Fly from Myrtle Beach Intl to Indianapolis for the best Myrtle Beach Intl - Indianapolis flight prices

What cabin class options are available on Myrtle Beach Intl to Indianapolis flights?

There is only 1 cabin class available to choose from on Myrtle Beach Intl to Indianapolis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Indianapolis flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Indianapolis.

How have Myrtle Beach to Indianapolis flight prices changed over time?

As of January 2026, prices for Myrtle Beach to Indianapolis flights are approximately 158% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Indianapolis (MYR to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Indianapolis

Fastest flight time

4h 47m

Direct flights

None
The fastest flight from Myrtle Beach to Indianapolis takes 4h 47m
There are no direct flights from Myrtle Beach to Indianapolis. There are no popular flight routes from Myrtle Beach to Indianapolis.
Search flight deals

  • How far is Myrtle Beach Intl to Indianapolis by plane?

    A flight from Myrtle Beach Intl to Indianapolis will travel around 581.0 mi. Flights usually cover this in 4h 47m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Indianapolis Airport?

    Prices for flights from Myrtle Beach Intl Airport to Indianapolis Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Indianapolis Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Indianapolis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents you'll need for your trip to Indianapolis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Indianapolis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Indianapolis?

  • What is the most popular airline from Myrtle Beach to Indianapolis?

Best airlines flying from Myrtle Beach to Indianapolis

Compare and see reviews for airlines that fly from Myrtle Beach to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $146Free CancellationRating
6.3
8,288 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $271Free CancellationRating
7.2
11,097 reviews
Search American Airlines flights
DeltaPriceFrom $286Free CancellationRating
7.9
8,026 reviews
Search Delta flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Plainfield
Anderson
Greenwood
Noblesville
Fishers
Carmel
Shelbyville
Franklin
West Lafayette
Seymour
Brownsburg
Crawfordsville
Speedway
Greenfield
Westfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Indianapolis?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Indianapolis from Myrtle Beach.

Can I find flights from Myrtle Beach to Indianapolis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Indianapolis from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Indianapolis?

Once all potential Myrtle Beach to Indianapolis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Myrtle Beach to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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