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Cheap flights from Myrtle Beach to Indianapolis from $187

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Indianapolis

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
9:05 am - 2:56 pmMYR  Myrtle Beach Intl-IND Indianapolis
5h 51m1 stop Charlotte Douglas
American Airlines Logo
7:26 am - 12:10 pmIND  Indianapolis-MYR Myrtle Beach Intl
4h 44m1 stop Washington, D.C. Reagan-National
$368American Airlines
Fri, Dec 25 - Tue, Jan 5
American Airlines Logo
11:52 am - 4:05 pmMYR  Myrtle Beach Intl-IND Indianapolis
4h 13m1 stop Washington, D.C. Reagan-National
American Airlines Logo
4:16 pm - 9:00 pmIND  Indianapolis-MYR Myrtle Beach Intl
4h 44m1 stop Charlotte Douglas
$373American Airlines
Thu, Dec 3 - Mon, Dec 7
American Airlines Logo
5:08 am - 9:30 amMYR  Myrtle Beach Intl-IND Indianapolis
4h 22m1 stop Charlotte Douglas
American Airlines Logo
11:14 am - 4:37 pmIND  Indianapolis-MYR Myrtle Beach Intl
5h 23m1 stop Charlotte Douglas
$373American Airlines
Thu, Dec 3 - Mon, Dec 7
American Airlines Logo
11:09 am - 4:16 pmMYR  Myrtle Beach Intl-IND Indianapolis
5h 07m1 stop Philadelphia
American Airlines Logo
7:26 am - 3:43 pmIND  Indianapolis-MYR Myrtle Beach Intl
8h 17m2 stops Washington, D.C. Reagan-National Charlotte Douglas
$373American Airlines
Fri, Dec 25 - Tue, Jan 5
Delta Logo
3:39 pm - 10:15 pmMYR  Myrtle Beach Intl-IND Indianapolis
6h 36m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:10 am - 10:39 amIND  Indianapolis-MYR Myrtle Beach Intl
4h 29m1 stop Detroit Metropolitan Wayne County
$380Delta
Wed, Dec 30 - Sat, Jan 2
Multiple Airlines Logo
2:46 pm - 10:01 amMYR  Myrtle Beach Intl-IND Indianapolis
19h 15m1 stop Orlando
Multiple Airlines Logo
6:15 pm - 8:45 amIND  Indianapolis-MYR Myrtle Beach Intl
14h 30m1 stop Orlando
$384Multiple Airlines
Sun, Nov 22 - Thu, Nov 26
United Airlines Logo
6:32 pm - 11:39 pmMYR  Myrtle Beach Intl-IND Indianapolis
5h 07m1 stop Newark
United Airlines Logo
12:00 pm - 5:34 pmIND  Indianapolis-MYR Myrtle Beach Intl
5h 34m1 stop Newark
$458United Airlines
Sat, Dec 5 - Wed, Dec 9
Southwest Logo
2:55 pm - 11:50 pmMYR  Myrtle Beach Intl-IND Indianapolis
8h 55m2 stops Baltimore/Washington Nashville Intl
Southwest Logo
5:20 am - 12:05 pmIND  Indianapolis-MYR Myrtle Beach Intl
6h 45m2 stops Baltimore/Washington Nashville Intl
$464Southwest
Wed, Dec 30 - Sat, Jan 2
Southwest Logo
7:15 pm - 12:45 amMYR  Myrtle Beach Intl-IND Indianapolis
5h 30m1 stop Baltimore/Washington
Southwest Logo
11:40 am - 6:30 pmIND  Indianapolis-MYR Myrtle Beach Intl
6h 50m1 stop Baltimore/Washington
$507Southwest
Tue, Nov 24 - Sat, Nov 28
Southwest Logo
10:35 am - 7:35 pmMYR  Myrtle Beach Intl-IND Indianapolis
9h 00m2 stops Nashville Intl Orlando
Southwest Logo
5:10 pm - 9:55 pmIND  Indianapolis-MYR Myrtle Beach Intl
4h 45m1 stop Baltimore/Washington
$512Southwest
Tue, Nov 24 - Sat, Nov 28

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United Airlines flights from Myrtle Beach to Indianapolis

Our best United Airlines deals on Myrtle Beach to Indianapolis flight tickets
United Airlines
Dec 5
MYR6:32 pmMyrtle Beach Intl
5h 07m
1 stop
IND11:39 pmIndianapolis
Dec 9
IND12:00 pmIndianapolis
5h 34m
1 stop
MYR5:34 pmMyrtle Beach Intl
$458
United Airlines
Dec 5
MYR6:32 pmMyrtle Beach Intl
5h 07m
1 stop
IND11:39 pmIndianapolis
Dec 9
IND12:00 pmIndianapolis
5h 34m
1 stop
MYR5:34 pmMyrtle Beach Intl
$515
United Airlines
Dec 5
MYR11:23 amMyrtle Beach Intl
12h 36m
2 stops
IND11:59 pmIndianapolis
Dec 9
IND12:00 pmIndianapolis
5h 34m
1 stop
MYR5:34 pmMyrtle Beach Intl
$518

American Airlines flights from Myrtle Beach to Indianapolis

Our best American Airlines deals on Myrtle Beach to Indianapolis flight tickets
American Airlines
Dec 23
MYR8:09 pmMyrtle Beach Intl
4h 22m
1 stop
IND12:31 amIndianapolis
Jan 5
IND12:02 pmIndianapolis
3h 41m
1 stop
MYR3:43 pmMyrtle Beach Intl
$274
American Airlines
Dec 23
MYR8:09 pmMyrtle Beach Intl
4h 22m
1 stop
IND12:31 amIndianapolis
Jan 5
IND6:00 amIndianapolis
6h 15m
2 stops
MYR12:15 pmMyrtle Beach Intl
$308
American Airlines
Dec 22
MYR8:09 pmMyrtle Beach Intl
4h 22m
1 stop
IND12:31 amIndianapolis
Jan 4
IND5:28 amIndianapolis
6h 47m
2 stops
MYR12:15 pmMyrtle Beach Intl
$337

momondo Fare Finder

 
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.

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Route

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Price

Cheapest round-trip

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Fri 12/25

9:05 am-2:56 pm

1 stop5h 51m

Indianapolis

Tue 1/5

7:26 am-12:10 pm

1 stop4h 44m

$368
Quickest round-trip

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Thu 12/3

11:52 am-4:05 pm

1 stop4h 13m

Indianapolis

Mon 12/7

4:16 pm-9:00 pm

1 stop4h 44m

$373

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Thu 12/3

5:08 am-9:30 am

1 stop4h 22m

Indianapolis

Mon 12/7

11:14 am-4:37 pm

1 stop5h 23m

$373

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Fri 12/25

11:09 am-4:16 pm

1 stop5h 07m

Indianapolis

Tue 1/5

7:26 am-3:43 pm

2 stops8h 17m

$373

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Wed 12/30

3:39 pm-10:15 pm

1 stop6h 36m

Indianapolis

Sat 1/2

6:10 am-10:39 am

1 stop4h 29m

$380

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Sun 11/22

2:46 pm-10:01 am

1 stop19h 15m

Indianapolis

Thu 11/26

6:15 pm-8:45 am

1 stop14h 30m

$384

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Sat 12/5

6:32 pm-11:39 pm

1 stop5h 07m

Indianapolis

Wed 12/9

12:00 pm-5:34 pm

1 stop5h 34m

$458

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Wed 12/30

2:55 pm-11:50 pm

2 stops8h 55m

Indianapolis

Sat 1/2

5:20 am-12:05 pm

2 stops6h 45m

$464

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Tue 11/24

7:15 pm-12:45 am

1 stop5h 30m

Indianapolis

Sat 11/28

11:40 am-6:30 pm

1 stop6h 50m

$507

Myrtle BeachIndianapolis

MYR Myrtle Beach Intl - IND Indianapolis

MYRIND

Myrtle Beach Intl

Tue 11/24

10:35 am-7:35 pm

2 stops9h 00m

Indianapolis

Sat 11/28

5:10 pm-9:55 pm

1 stop4h 45m

$512

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Indianapolis from

How to get the cheapest flight ticket from Myrtle Beach to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Indianapolis?

Prices are currently low for flights on this route.

Typical prices usually range from $334 to $446.
The lowest price recently found on this route was $271.

What is the cheapest month to fly to Indianapolis?

In general, January is the cheapest month to fly from Myrtle Beach to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you are unable to visit Indianapolis during the month of January, then departing from Myrtle Beach during the month October is also very affordable. Most momondo users find prices during this month for around $270.

What is the cheapest Myrtle Beach Intl to Indianapolis flight route?

Fly from Myrtle Beach Intl to Indianapolis for the best Myrtle Beach Intl - Indianapolis flight prices

What cabin class options are available on Myrtle Beach to Indianapolis flights?

There is only 1 cabin class available to choose from on Myrtle Beach to Indianapolis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Indianapolis flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Indianapolis.

How have Myrtle Beach to Indianapolis flight prices changed over time?

As of November 2026, prices for Myrtle Beach to Indianapolis flights are approximately 121% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Indianapolis (MYR to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Indianapolis

Best Price Found

$187

Fastest flight time

4h 38m

Direct flights

None
The best one-way flight to Indianapolis from Myrtle Beach in the past 72 hours is $187. The best round-trip flight deal from Myrtle Beach to Indianapolis found on momondo in the last 72 hours is $368.
The fastest flight from Myrtle Beach to Indianapolis takes 4h 38m
There are no direct flights from Myrtle Beach to Indianapolis. There are no popular flight routes from Myrtle Beach to Indianapolis.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Indianapolis

  • How far is Myrtle Beach Intl to Indianapolis by plane?

    A flight from Myrtle Beach Intl to Indianapolis will travel around 581.0 mi. Flights usually cover this in 4h 38m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Indianapolis Airport?

    Prices for flights from Myrtle Beach Intl Airport to Indianapolis Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Indianapolis Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Indianapolis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents you'll need for your trip to Indianapolis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Indianapolis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Indianapolis?

  • What is the most popular airline from Myrtle Beach to Indianapolis?

Best airlines flying from Myrtle Beach to Indianapolis

Compare and see reviews for airlines that fly from Myrtle Beach to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $246Free CancellationRating
8.0
4,219 reviews
Search Southwest flights
American AirlinesPriceFrom $270Free CancellationRating
7.0
12,227 reviews
Search American Airlines flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Greenwood
Anderson
Plainfield
Noblesville
Carmel
Fishers
West Lafayette
Speedway
Franklin
Westfield
Shelbyville
Crawfordsville
Brownsburg
Seymour
Greenfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Indianapolis?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Indianapolis from Myrtle Beach.

Can I find flights from Myrtle Beach to Indianapolis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Indianapolis from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Indianapolis?

Once all potential Myrtle Beach to Indianapolis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Myrtle Beach to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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