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Cheap flights from Myrtle Beach to Indianapolis from $81

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Indianapolis departing on 6/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
11:52 am - 11:57 pm
MYR
-
IND
12h 05m
1 stop
Spirit Airlines Logo
6:00 am - 10:55 am
IND
-
MYR
4h 55m
1 stop
$276Spirit Airlines
Fri, May 8 - Sun, May 10
Multiple Airlines Logo
4:15 pm - 11:22 am
MYR
-
IND
19h 07m
1 stop
Multiple Airlines Logo
6:40 pm - 7:33 pm
IND
-
MYR
24h 53m
1 stop
$277Multiple Airlines
Fri, May 15 - Mon, May 18
Multiple Airlines Logo
12:05 pm - 11:23 am
MYR
-
IND
23h 18m
2 stops
Multiple Airlines Logo
6:00 am - 8:52 am
IND
-
MYR
26h 52m
1 stop
$286Multiple Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
6:04 am - 9:41 am
MYR
-
IND
3h 37m
1 stop
American Airlines Logo
5:34 pm - 11:57 pm
IND
-
MYR
6h 23m
1 stop
$289American Airlines
Thu, Apr 9 - Mon, Apr 13
Spirit Airlines Logo
11:52 am - 11:59 pm
MYR
-
IND
12h 07m
1 stop
Spirit Airlines Logo
6:00 am - 7:04 pm
IND
-
MYR
13h 04m
1 stop
$291Spirit Airlines
Sat, May 2 - Sun, May 3
Spirit Airlines Logo
6:28 pm - 10:32 pm
MYR
-
IND
28h 04m
1 stop
Spirit Airlines Logo
5:45 am - 5:33 pm
IND
-
MYR
11h 48m
1 stop
$301Spirit Airlines
Tue, Mar 31 - Sat, Apr 4
Multiple Airlines Logo
4:15 pm - 11:22 am
MYR
-
IND
19h 07m
1 stop
Multiple Airlines Logo
12:14 pm - 8:44 am
IND
-
MYR
20h 30m
2 stops
$312Multiple Airlines
Fri, May 15 - Mon, May 18
Multiple Airlines Logo
11:28 am - 10:32 pm
MYR
-
IND
11h 04m
1 stop
Multiple Airlines Logo
5:45 am - 5:33 pm
IND
-
MYR
11h 48m
1 stop
$313Multiple Airlines
Wed, Apr 1 - Fri, Apr 3
Multiple Airlines Logo
4:40 pm - 11:17 am
MYR
-
IND
18h 37m
2 stops
Multiple Airlines Logo
1:56 pm - 11:29 pm
IND
-
MYR
9h 33m
1 stop
$323Multiple Airlines
Sat, May 2 - Sun, May 3
Multiple Airlines Logo
11:28 am - 10:32 pm
MYR
-
IND
11h 04m
1 stop
Multiple Airlines Logo
7:09 pm - 11:05 am
IND
-
MYR
15h 56m
1 stop
$328Multiple Airlines
Wed, Apr 1 - Sat, Apr 4

American Airlines flights from Myrtle Beach to Indianapolis

Our best American Airlines deals on Myrtle Beach to Indianapolis flight tickets
American Airlines
Apr 9
MYR6:04 amMyrtle Beach Intl
3h 37m
1 stop
IND9:41 amIndianapolis
Apr 13
IND5:34 pmIndianapolis
6h 23m
1 stop
MYR11:57 pmMyrtle Beach Intl
$289
American Airlines
May 21
MYR4:43 pmMyrtle Beach Intl
6h 01m
1 stop
IND10:44 pmIndianapolis
May 26
IND11:29 amIndianapolis
4h 29m
1 stop
MYR3:58 pmMyrtle Beach Intl
$338
American Airlines
Mar 29
MYR5:10 amMyrtle Beach Intl
4h 22m
1 stop
IND9:32 amIndianapolis
Apr 5
IND8:00 amIndianapolis
6h 27m
1 stop
MYR2:27 pmMyrtle Beach Intl
$437

Spirit Airlines flights from Myrtle Beach to Indianapolis

Our best Spirit Airlines deals on Myrtle Beach to Indianapolis flight tickets
Spirit Airlines
Mar 26
MYR9:49 pmMyrtle Beach Intl
25h 26m
1 stop
IND11:15 pmIndianapolis
Apr 1
IND5:45 amIndianapolis
11h 48m
1 stop
MYR5:33 pmMyrtle Beach Intl
$276
Spirit Airlines
Mar 27
MYR10:01 amMyrtle Beach Intl
13h 14m
1 stop
IND11:15 pmIndianapolis
Apr 1
IND5:45 amIndianapolis
11h 48m
1 stop
MYR5:33 pmMyrtle Beach Intl
$291
Spirit Airlines
Mar 31
MYR6:28 pmMyrtle Beach Intl
28h 04m
1 stop
IND10:32 pmIndianapolis
Apr 4
IND5:45 amIndianapolis
11h 48m
1 stop
MYR5:33 pmMyrtle Beach Intl
$301

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 5/8

11:52 am-11:57 pm

1 stop12h 05m

Indianapolis

Sun 5/10

6:00 am-10:55 am

1 stop4h 55m

$276

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 5/15

4:15 pm-11:22 am

1 stop19h 07m

Indianapolis

Mon 5/18

6:40 pm-7:33 pm

1 stop24h 53m

$277

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 4/9

12:05 pm-11:23 am

2 stops23h 18m

Indianapolis

Mon 4/13

6:00 am-8:52 am

1 stop26h 52m

$286
Quickest round-trip

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 4/9

6:04 am-9:41 am

1 stop3h 37m

Indianapolis

Mon 4/13

5:34 pm-11:57 pm

1 stop6h 23m

$289

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sat 5/2

11:52 am-11:59 pm

1 stop12h 07m

Indianapolis

Sun 5/3

6:00 am-7:04 pm

1 stop13h 04m

$291

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Tue 3/31

6:28 pm-10:32 pm

1 stop28h 04m

Indianapolis

Sat 4/4

5:45 am-5:33 pm

1 stop11h 48m

$301

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 5/15

4:15 pm-11:22 am

1 stop19h 07m

Indianapolis

Mon 5/18

12:14 pm-8:44 am

2 stops20h 30m

$312

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 4/1

11:28 am-10:32 pm

1 stop11h 04m

Indianapolis

Fri 4/3

5:45 am-5:33 pm

1 stop11h 48m

$313

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sat 5/2

4:40 pm-11:17 am

2 stops18h 37m

Indianapolis

Sun 5/3

1:56 pm-11:29 pm

1 stop9h 33m

$323

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 4/1

11:28 am-10:32 pm

1 stop11h 04m

Indianapolis

Sat 4/4

7:09 pm-11:05 am

1 stop15h 56m

$328

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Indianapolis from

How to get the cheapest flight ticket from Myrtle Beach to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest Myrtle Beach Intl to Indianapolis flight route?

Fly from Myrtle Beach Intl to Indianapolis for the best Myrtle Beach Intl - Indianapolis flight prices

What cabin class options are available on Myrtle Beach Intl to Indianapolis flights?

There is only 1 cabin class available to choose from on Myrtle Beach Intl to Indianapolis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Indianapolis flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Indianapolis.

How have Myrtle Beach to Indianapolis flight prices changed over time?

As of March 2026, prices for Myrtle Beach to Indianapolis flights are approximately 126% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Indianapolis (MYR to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Indianapolis

Fastest flight time

4h 38m

Direct flights

Sun

Airports in Indianapolis

1 airport
The fastest flight from Myrtle Beach to Indianapolis takes 4h 38m
Direct flights go from Myrtle Beach to Indianapolis on Sunday. The only airline offering direct flights is Allegiant Air.
There is 1 airport in Indianapolis. From Myrtle Beach there are direct flights to Indianapolis (IND).
Search flight deals

  • How far is Myrtle Beach Intl to Indianapolis by plane?

    A flight from Myrtle Beach Intl to Indianapolis will travel around 581.0 mi. Flights usually cover this in 4h 38m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Indianapolis Airport?

    Prices for flights from Myrtle Beach Intl Airport to Indianapolis Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Indianapolis Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Indianapolis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents you'll need for your trip to Indianapolis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Indianapolis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Indianapolis?

  • What is the most popular airline from Myrtle Beach to Indianapolis?

Best airlines flying from Myrtle Beach to Indianapolis

Compare and see reviews for airlines that fly from Myrtle Beach to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $83Free CancellationRating
6.3
8,523 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $271Free CancellationRating
7.1
11,468 reviews
Search American Airlines flights
DeltaPriceFrom $341Free CancellationRating
7.9
8,286 reviews
Search Delta flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Plainfield
Anderson
Greenwood
Noblesville
Carmel
Fishers
Shelbyville
Franklin
Seymour
West Lafayette
Speedway
Brownsburg
Crawfordsville
Westfield
Greenfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Indianapolis?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Indianapolis from Myrtle Beach.

Can I find flights from Myrtle Beach to Indianapolis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Indianapolis from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Indianapolis?

Once all potential Myrtle Beach to Indianapolis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Myrtle Beach to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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