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Cheap flights from Myrtle Beach to Indianapolis from $121

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Indianapolis departing on 12/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Spirit Airlines Logo
2:46 pm - 11:29 pmMYR-IND
8h 43m1 stop
Spirit Airlines Logo
5:05 am - 10:08 amIND-MYR
5h 03m1 stop
$174Spirit Airlines
Find Deal
jue., nov. 13 - dom., nov. 16
Spirit Airlines Logo
1:12 pm - 6:11 pmMYR-IND
4h 59m1 stop
Spirit Airlines Logo
5:05 am - 10:08 amIND-MYR
5h 03m1 stop
$192Spirit Airlines
Find Deal
jue., oct. 30 - dom., nov. 2
Spirit Airlines Logo
2:46 pm - 12:51 amMYR-IND
10h 05m1 stop
Spirit Airlines Logo
5:05 am - 10:08 amIND-MYR
5h 03m1 stop
$193Spirit Airlines
Find Deal
vie., nov. 14 - dom., nov. 16
Multiple Airlines Logo
6:18 pm - 10:50 amMYR-IND
40h 32m2 stops
Multiple Airlines Logo
1:28 pm - 2:58 pmIND-MYR
25h 30m1 stop
$263Multiple Airlines
Find Deal
sáb., dic. 6 - mar., dic. 16
American Airlines Logo
5:21 am - 11:24 amMYR-IND
6h 03m1 stop
American Airlines Logo
1:07 pm - 5:06 pmIND-MYR
3h 59m1 stop
$297American Airlines
Find Deal
sáb., oct. 25 - mié., oct. 29
American Airlines Logo
12:09 pm - 7:11 pmMYR-IND
7h 02m2 stops
American Airlines Logo
6:00 am - 10:32 amIND-MYR
4h 32m1 stop
$302American Airlines
Find Deal
mar., dic. 16 - jue., dic. 25
Southwest Logo
10:35 am - 4:55 pmMYR-IND
6h 20m1 stop
Southwest Logo
7:00 am - 5:00 pmIND-MYR
10h 00m2 stops
$347Southwest
Find Deal
dom., mar. 1 - mié., mar. 4
Southwest Logo
1:20 pm - 8:15 pmMYR-IND
6h 55m1 stop
Southwest Logo
5:05 am - 10:00 amIND-MYR
4h 55m1 stop
$360Southwest
Find Deal
vie., ene. 16 - lun., ene. 19
Delta Logo
6:45 pm - 11:57 pmMYR-IND
5h 12m1 stop
Delta Logo
6:05 am - 12:01 pmIND-MYR
5h 56m1 stop
$387Delta
Find Deal
mar., mar. 10 - mié., mar. 11
Delta Logo
6:00 am - 10:33 amMYR-IND
4h 33m1 stop
Delta Logo
6:05 am - 12:01 pmIND-MYR
5h 56m1 stop
$392Delta
Find Deal
mar., mar. 10 - mié., mar. 11

Spirit Airlines flights from Myrtle Beach to Indianapolis

Our best Spirit Airlines deals on Myrtle Beach to Indianapolis flight tickets
Spirit Airlines
Nov 13
MYR2:46 pmMyrtle Beach Intl
8h 43m
1 stop
IND11:29 pmIndianapolis
Nov 16
IND5:05 amIndianapolis
5h 03m
1 stop
MYR10:08 amMyrtle Beach Intl
$174
Find similar
Spirit Airlines
Oct 30
MYR1:12 pmMyrtle Beach Intl
4h 59m
1 stop
IND6:11 pmIndianapolis
Nov 2
IND5:05 amIndianapolis
5h 03m
1 stop
MYR10:08 amMyrtle Beach Intl
$192
Find similar
Spirit Airlines
Nov 14
MYR2:46 pmMyrtle Beach Intl
10h 05m
1 stop
IND12:51 amIndianapolis
Nov 16
IND5:05 amIndianapolis
5h 03m
1 stop
MYR10:08 amMyrtle Beach Intl
$193
Find similar

Delta flights from Myrtle Beach to Indianapolis

Our best Delta deals on Myrtle Beach to Indianapolis flight tickets
Delta
Mar 10
MYR6:45 pmMyrtle Beach Intl
5h 12m
1 stop
IND11:57 pmIndianapolis
Mar 11
IND6:05 amIndianapolis
5h 56m
1 stop
MYR12:01 pmMyrtle Beach Intl
$387
Find similar
Delta
Mar 10
MYR6:00 amMyrtle Beach Intl
4h 33m
1 stop
IND10:33 amIndianapolis
Mar 11
IND6:05 amIndianapolis
5h 56m
1 stop
MYR12:01 pmMyrtle Beach Intl
$392
Find similar
Delta
Oct 17
MYR6:00 amMyrtle Beach Intl
4h 33m
1 stop
IND10:33 amIndianapolis
Oct 19
IND6:30 amIndianapolis
4h 04m
1 stop
MYR10:34 amMyrtle Beach Intl
$487
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 7, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

jue. 11/13

2:46 pm-11:29 pm

1 stop8h 43m

Indianapolis

dom. 11/16

5:05 am-10:08 am

1 stop5h 03m

$174

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

jue. 10/30

1:12 pm-6:11 pm

1 stop4h 59m

Indianapolis

dom. 11/2

5:05 am-10:08 am

1 stop5h 03m

$192

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

vie. 11/14

2:46 pm-12:51 am

1 stop10h 05m

Indianapolis

dom. 11/16

5:05 am-10:08 am

1 stop5h 03m

$193

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

sáb. 12/6

6:18 pm-10:50 am

2 stops40h 32m

Indianapolis

mar. 12/16

1:28 pm-2:58 pm

1 stop25h 30m

$263

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

sáb. 10/25

5:21 am-11:24 am

1 stop6h 03m

Indianapolis

mié. 10/29

1:07 pm-5:06 pm

1 stop3h 59m

$297

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

mar. 12/16

12:09 pm-7:11 pm

2 stops7h 02m

Indianapolis

jue. 12/25

6:00 am-10:32 am

1 stop4h 32m

$302

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

dom. 3/1

10:35 am-4:55 pm

1 stop6h 20m

Indianapolis

mié. 3/4

7:00 am-5:00 pm

2 stops10h 00m

$347

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

vie. 1/16

1:20 pm-8:15 pm

1 stop6h 55m

Indianapolis

lun. 1/19

5:05 am-10:00 am

1 stop4h 55m

$360

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

mar. 3/10

6:45 pm-11:57 pm

1 stop5h 12m

Indianapolis

mié. 3/11

6:05 am-12:01 pm

1 stop5h 56m

$387

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

mar. 3/10

6:00 am-10:33 am

1 stop4h 33m

Indianapolis

mié. 3/11

6:05 am-12:01 pm

1 stop5h 56m

$392

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Indianapolis from

How to get the cheapest flight ticket from Myrtle Beach to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Indianapolis?

In general, August is the cheapest month to fly from Myrtle Beach to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $184. If you are unable to visit Indianapolis during the month of August, then departing from Myrtle Beach during the month June is also very affordable. Most momondo users find prices during this month for around $231.

What is the cheapest day to depart on your flight to Indianapolis?

Our data shows that Monday is the least expensive day to fly to Indianapolis. Tickets to fly out on this day can be as low as $238. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Indianapolis on Sunday is $480.

What is the cheapest Myrtle Beach Intl to Indianapolis flight route?

Fly from Myrtle Beach Intl to Indianapolis for the best Myrtle Beach Intl - Indianapolis flight prices

What cabin class options are available on Myrtle Beach Intl to Indianapolis flights?

There is only 1 cabin class available to choose from on Myrtle Beach Intl to Indianapolis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Indianapolis flights?

You could potentially save up to 5% on your flight if you consider stops on a Myrtle Beach to Indianapolis flight.

How have Myrtle Beach to Indianapolis flight prices changed over time?

As of October 2025, prices for Myrtle Beach to Indianapolis flights are approximately 5% cheaper when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Indianapolis (MYR to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Indianapolis

Direct flights

None
There are no direct flights from Myrtle Beach to Indianapolis. There are no popular flight routes from Myrtle Beach to Indianapolis.
Search flight deals

  • How far is Myrtle Beach Intl to Indianapolis by plane?

    A flight from Myrtle Beach Intl to Indianapolis will travel around 581.0 mi. Flights usually cover this in 3h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Indianapolis Airport?

    Prices for flights from Myrtle Beach Intl Airport to Indianapolis Airport refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Indianapolis Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Indianapolis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents you'll need for your trip to Indianapolis Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Indianapolis Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Indianapolis?

  • What is the most popular airline from Myrtle Beach to Indianapolis?

Best airlines flying from Myrtle Beach to Indianapolis

Compare and see reviews for airlines that fly from Myrtle Beach to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $149Free CancellationRating
6.3
8,080 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $271Free CancellationRating
7.2
11,041 reviews
Search American Airlines flights
DeltaPriceFrom $286Free CancellationRating
7.9
7,969 reviews
Search Delta flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Anderson
Plainfield
Greenwood
Noblesville
Fishers
Carmel
Shelbyville
West Lafayette
Seymour
Franklin
Brownsburg
Crawfordsville
Speedway
Greenfield
Westfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Indianapolis?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Indianapolis from Myrtle Beach.

Can I find flights from Myrtle Beach to Indianapolis with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Indianapolis from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Indianapolis?

Once all potential Myrtle Beach to Indianapolis flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Myrtle Beach to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
jue. 11/6
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