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Cheap flights from Missouri to Boston from $157

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Boston departing on 4/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:05 am - 11:22 pm
STL
-
PWM
15h 17m
1 stop
American Airlines Logo
7:07 am - 4:41 pm
PWM
-
STL
10h 34m
1 stop
$295American Airlines
Wed, May 13 - Tue, May 19
Delta Logo
4:20 pm - 12:43 am
STL
-
PWM
7h 23m
1 stop
Delta Logo
6:00 am - 12:20 pm
PWM
-
STL
7h 20m
1 stop
$299Delta
Tue, May 12 - Tue, May 19
American Airlines Logo
7:05 am - 11:27 pm
STL
-
PWM
15h 22m
1 stop
American Airlines Logo
7:07 am - 10:19 pm
PWM
-
STL
16h 12m
1 stop
$305American Airlines
Sat, Apr 11 - Tue, Apr 14
American Airlines Logo
5:51 am - 11:22 pm
STL
-
PWM
16h 31m
1 stop
American Airlines Logo
7:07 am - 2:03 pm
PWM
-
STL
7h 56m
1 stop
$307American Airlines
Thu, May 14 - Wed, May 20
Delta Logo
3:56 pm - 11:22 pm
SGF
-
PWM
6h 26m
1 stop
Delta Logo
5:23 am - 11:07 am
PWM
-
SGF
6h 44m
1 stop
$309Delta
Fri, Mar 27 - Fri, Apr 3
Delta Logo
3:06 pm - 11:12 pm
MCI
-
PWM
7h 06m
1 stop
Delta Logo
2:05 pm - 8:47 pm
PWM
-
MCI
7h 42m
1 stop
$313Delta
Tue, May 12 - Wed, May 20
United Airlines Logo
11:30 am - 5:32 pm
MCI
-
PWM
5h 02m
1 stop
United Airlines Logo
11:34 am - 6:15 pm
PWM
-
MCI
7h 41m
1 stop
$332United Airlines
Tue, Apr 28 - Sat, May 2
United Airlines Logo
8:00 am - 2:14 pm
COU
-
PWM
5h 14m
1 stop
United Airlines Logo
6:00 am - 10:55 am
PWM
-
COU
5h 55m
1 stop
$335United Airlines
Sat, May 2 - Thu, May 7
Southwest Logo
1:50 pm - 11:05 pm
MCI
-
PWM
8h 15m
2 stops
Southwest Logo
3:50 pm - 10:30 pm
PWM
-
MCI
7h 40m
2 stops
$356Southwest
Wed, Apr 1 - Tue, Apr 7
Multiple Airlines Logo
2:15 pm - 4:16 pm
MCI
-
PWM
49h 01m
2 stops
Multiple Airlines Logo
6:26 pm - 10:22 am
PWM
-
MCI
16h 56m
1 stop
$361Multiple Airlines
Thu, May 14 - Wed, May 20

Delta flights from Missouri to Portland, Maine

Our best Delta deals on Missouri to Portland, Maine flight tickets
Delta
May 12
STL9:30 amLambert-St Louis
6h 05m
1 stop
PWM4:35 pmPortland
May 20
PWM11:03 amPortland
5h 32m
1 stop
STL3:35 pmLambert-St Louis
$299
Delta
Mar 27
SGF3:56 pmSpringfield-Branson
6h 26m
1 stop
PWM11:22 pmPortland
Apr 3
PWM5:23 amPortland
6h 44m
1 stop
SGF11:07 amSpringfield-Branson
$309
Delta
May 12
MCI3:06 pmKansas City
7h 06m
1 stop
PWM11:12 pmPortland
May 20
PWM2:05 pmPortland
7h 42m
1 stop
MCI8:47 pmKansas City
$313

United Airlines flights from Missouri to Portland, Maine

Our best United Airlines deals on Missouri to Portland, Maine flight tickets
United Airlines
Apr 28
MCI11:30 amKansas City
5h 02m
1 stop
PWM5:32 pmPortland
May 2
PWM11:34 amPortland
7h 41m
1 stop
MCI6:15 pmKansas City
$332
United Airlines
May 2
COU8:00 amColumbia Regional
5h 14m
1 stop
PWM2:14 pmPortland
May 7
PWM6:00 amPortland
5h 55m
1 stop
COU10:55 amColumbia Regional
$335
United Airlines
Apr 1
MCI6:15 amKansas City
7h 22m
2 stops
PWM2:37 pmPortland
Apr 7
PWM6:04 amPortland
5h 23m
1 stop
MCI10:27 amKansas City
$337

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Portland, Maine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 28, 2026.
Use the filters below to find and compare flights from Missouri to Portland, Maine that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisPortland

STL - PWM

STLPWM

Lambert-St Louis

Wed 5/13

7:05 am-11:22 pm

1 stop15h 17m

Portland

Tue 5/19

7:07 am-4:41 pm

1 stop10h 34m

$295

St. LouisPortland

STL - PWM

STLPWM

Lambert-St Louis

Tue 5/12

4:20 pm-12:43 am

1 stop7h 23m

Portland

Tue 5/19

6:00 am-12:20 pm

1 stop7h 20m

$299

St. LouisPortland

STL - PWM

STLPWM

Lambert-St Louis

Sat 4/11

7:05 am-11:27 pm

1 stop15h 22m

Portland

Tue 4/14

7:07 am-10:19 pm

1 stop16h 12m

$305

St. LouisPortland

STL - PWM

STLPWM

Lambert-St Louis

Thu 5/14

5:51 am-11:22 pm

1 stop16h 31m

Portland

Wed 5/20

7:07 am-2:03 pm

1 stop7h 56m

$307

SpringfieldPortland

SGF - PWM

SGFPWM

Springfield-Branson

Fri 3/27

3:56 pm-11:22 pm

1 stop6h 26m

Portland

Fri 4/3

5:23 am-11:07 am

1 stop6h 44m

$309

Kansas CityPortland

MCI - PWM

MCIPWM

Kansas City

Tue 5/12

3:06 pm-11:12 pm

1 stop7h 06m

Portland

Wed 5/20

2:05 pm-8:47 pm

1 stop7h 42m

$313

Kansas CityPortland

MCI - PWM

MCIPWM

Kansas City

Tue 4/28

11:30 am-5:32 pm

1 stop5h 02m

Portland

Sat 5/2

11:34 am-6:15 pm

1 stop7h 41m

$332

ColumbiaPortland

COU - PWM

COUPWM

Columbia Regional

Sat 5/2

8:00 am-2:14 pm

1 stop5h 14m

Portland

Thu 5/7

6:00 am-10:55 am

1 stop5h 55m

$335

Kansas CityPortland

MCI - PWM

MCIPWM

Kansas City

Wed 4/1

1:50 pm-11:05 pm

2 stops8h 15m

Portland

Tue 4/7

3:50 pm-10:30 pm

2 stops7h 40m

$356

Kansas CityPortland

MCI - PWM

MCIPWM

Kansas City

Thu 5/14

2:15 pm-4:16 pm

2 stops49h 01m

Portland

Wed 5/20

6:26 pm-10:22 am

1 stop16h 56m

$361

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Missouri to Portland, Maine

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Portland, Maine?

The cheapest month to fly to Portland, Maine from Missouri is in March. Flight prices, which tend to average around $349, are often lower during this time because this is during the off-season. If you aren’t able to travel to Portland, Maine during the month of March, then flying in December is also cheap. Prices for this month can be found on momondo for an average of $386.

How far in advance should I book a flight to Portland, Maine?

You are more likely to see cheaper flights to Portland, Maine from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Portland, Maine for around $432 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Portland, Maine from Missouri for as low as $334 on momondo.

Cheap Missouri to Portland, Maine flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Portland, Maine

Fastest flight time

4h 15m

Direct flights

None
The fastest flight from Missouri to Portland, Maine takes 4h 15m
There are no direct flights from Missouri to Portland, Maine. There are no popular flight routes from Missouri to Portland, Maine.
Search flight deals

  • When did momondo last update prices for flights from Missouri to Portland Airport?

    Prices for flights from Missouri to Portland Airport are updated daily.

  • How many operators does momondo search for flights from Missouri to Portland Airport?

  • How old do you have to be to fly from Missouri to Portland Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Portland Airport.

  • What documentation or ID do you need to fly to Portland Airport?

    The travel and health documents required for your trip to Portland Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Portland Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Portland, Maine

Compare and see reviews for airlines that fly from Missouri to Portland, Maine with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $128Free CancellationRating
7.9
8,245 reviews
Search Delta flights
United AirlinesPriceFrom $212Free CancellationRating
7.4
9,363 reviews
Search United Airlines flights
American AirlinesPriceFrom $274Free CancellationRating
7.1
11,367 reviews
Search American Airlines flights
SouthwestPriceFrom $284Free CancellationRating
8.0
4,303 reviews
Search Southwest flights

Traveling to a place near Boston?

Book flights to Boston if you plan to visit one of these locations
North Conway
Boothbay Harbor
Jackson
Conway
Freeport
Lewiston
Brunswick
Bartlett
Gorham
Auburn
Windham
Intervale
Bath
Oxford
Georgetown
Falmouth
Tamworth

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Portland?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Portland from Missouri.

Can I find flights from Missouri to Portland with flexible booking policies on momondo?

Yes. All flights to Portland from Missouri on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Missouri to Portland?

Once you have performed a search for Missouri to Portland flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Missouri to Portland right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Portland, momondo offers a useful price alert feature which will track prices for flights to Portland from Missouri and alert you when they change.

An easier way to manage your Portland, Maine trip

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