Cheap flights from Missouri to Massachusetts from $108

In general, August is the cheapest month to fly from Missouri to Massachusetts. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $83. If you aren’t able to travel to Massachusetts during the month of August, then flying in April is also cheap. Prices for this month can be found on momondo for an average of $95.

According to our data, Tuesday is the cheapest day to fly to Massachusetts from Missouri. The lowest ticket price found for a Tuesday departure recently was $617. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Saturday is the most expensive day to depart from Missouri because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $857.

Our data shows that the cheapest Missouri to Massachusetts flights are usually those with departure times in the afternoon. Our users have found flights to Massachusetts in the afternoon for as low as $491. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $774 on average. Flights to Massachusetts from Missouri in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Lambert-St Louis to Boston Logan Intl for the best Missouri - Massachusetts flight prices

You are more likely to see cheaper flights to Massachusetts from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Massachusetts for around $470 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Massachusetts from Missouri for as low as $361 on momondo.

There are 4 cabin classes available to choose from on Missouri to Massachusetts flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Allegiant Air, Delta, and Southwest are the most popular carriers operating from Missouri to Massachusetts

American Airlines, Southwest and Delta are the top three most popular airlines that fly to Massachusetts from Missouri according to our data. American Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Massachusetts. Keep in mind that there are 5 different airlines that fly to Massachusetts on a routine basis, so you have a few additional options to choose from.

As of June 2026, there are 7 flights per day flying from Missouri to Massachusetts. The most common time of day flights depart is 9:00AM, with 61% of flights taking off at noon.

As of June 2026, there are 52 flights per week flying from Missouri to Massachusetts. The most common day of the week flights depart is Thu, with 29% of flights taking off on this day.