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Cheap flights from Missouri to Buffalo from $143

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Buffalo departing on 5/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Missouri to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:23 pm - 12:13 pm
STL
-
BUF
14h 50m
1 stop
Frontier Logo
12:07 pm - 6:50 am
BUF
-
STL
19h 43m
1 stop
$203Frontier
dv., abr. 24 - dg., abr. 26
Frontier Logo
8:23 pm - 12:12 pm
STL
-
BUF
14h 49m
1 stop
Frontier Logo
2:49 pm - 8:55 am
BUF
-
STL
19h 06m
1 stop
$225Frontier
dc., abr. 29 - dv., maig 8
Frontier Logo
8:41 am - 7:31 pm
STL
-
BUF
9h 50m
1 stop
Frontier Logo
4:45 pm - 11:58 pm
BUF
-
STL
8h 13m
1 stop
$235Frontier
dl., abr. 6 - dv., abr. 10
Frontier Logo
8:23 pm - 12:12 pm
STL
-
BUF
14h 49m
1 stop
Frontier Logo
2:49 pm - 12:21 am
BUF
-
STL
10h 32m
2 stops
$254Frontier
dc., abr. 29 - dv., maig 8
American Airlines Logo
5:21 pm - 11:54 pm
MCI
-
BUF
5h 33m
1 stop
American Airlines Logo
10:44 am - 4:38 pm
BUF
-
MCI
6h 54m
1 stop
$263American Airlines
dt., juny 2 - dc., juny 10
Delta Logo
7:00 am - 11:58 pm
MCI
-
BUF
15h 58m
1 stop
Delta Logo
7:40 pm - 9:27 am
BUF
-
MCI
14h 47m
1 stop
$267Delta
dl., ag. 10 - dc., ag. 19
Delta Logo
12:39 pm - 6:27 pm
MCI
-
BUF
4h 48m
1 stop
Delta Logo
12:14 pm - 8:56 pm
BUF
-
MCI
9h 42m
1 stop
$276Delta
dt., juny 9 - dc., juny 17
United Airlines Logo
6:30 am - 1:13 pm
STL
-
BUF
5h 43m
1 stop
United Airlines Logo
7:00 am - 10:45 am
BUF
-
STL
4h 45m
1 stop
$297United Airlines
ds., abr. 18 - ds., abr. 25
United Airlines Logo
8:21 am - 6:13 pm
STL
-
BUF
8h 52m
2 stops
United Airlines Logo
7:00 am - 10:45 am
BUF
-
STL
4h 45m
1 stop
$302United Airlines
ds., abr. 18 - ds., abr. 25
American Airlines Logo
6:00 am - 2:21 pm
COU
-
BUF
7h 21m
1 stop
American Airlines Logo
6:00 pm - 9:30 pm
BUF
-
COU
4h 30m
1 stop
$318American Airlines
dj., abr. 23 - ds., abr. 25

Delta flights from Missouri to Buffalo

Our best Delta deals on Missouri to Buffalo flight tickets
Delta
Aug 10
MCI7:00 amKansas City
15h 58m
1 stop
BUF11:58 pmBuffalo
Aug 19
BUF7:40 pmBuffalo
14h 47m
1 stop
MCI9:27 amKansas City
$267
Delta
Jun 9
MCI12:39 pmKansas City
4h 48m
1 stop
BUF6:27 pmBuffalo
Jun 17
BUF12:14 pmBuffalo
9h 42m
1 stop
MCI8:56 pmKansas City
$276
Delta
Aug 15
MCI5:26 pmKansas City
16h 49m
1 stop
BUF11:15 amBuffalo
Aug 21
BUF7:40 pmBuffalo
15h 22m
1 stop
MCI10:02 amKansas City
$305

Southwest flights from Missouri to Buffalo

Our best Southwest deals on Missouri to Buffalo flight tickets
Southwest
Apr 18
STL6:10 amLambert-St Louis
9h 25m
2 stops
BUF4:35 pmBuffalo
Apr 25
BUF6:00 amBuffalo
8h 35m
2 stops
STL1:35 pmLambert-St Louis
$307
Southwest
Aug 19
STL10:45 amLambert-St Louis
3h 30m
1 stop
BUF3:15 pmBuffalo
Aug 22
BUF5:45 amBuffalo
6h 05m
1 stop
STL10:50 amLambert-St Louis
$362
Southwest
Apr 18
MCI5:20 amKansas City
7h 55m
2 stops
BUF2:15 pmBuffalo
Apr 25
BUF12:30 pmBuffalo
8h 30m
2 stops
MCI8:00 pmKansas City
$367

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated març 24, 2026.
Use the filters below to find and compare flights from Missouri to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

dv. 4/24

8:23 pm-12:13 pm

1 stop14h 50m

Buffalo

dg. 4/26

12:07 pm-6:50 am

1 stop19h 43m

$203

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

dc. 4/29

8:23 pm-12:12 pm

1 stop14h 49m

Buffalo

dv. 5/8

2:49 pm-8:55 am

1 stop19h 06m

$225

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

dl. 4/6

8:41 am-7:31 pm

1 stop9h 50m

Buffalo

dv. 4/10

4:45 pm-11:58 pm

1 stop8h 13m

$235

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

dc. 4/29

8:23 pm-12:12 pm

1 stop14h 49m

Buffalo

dv. 5/8

2:49 pm-12:21 am

2 stops10h 32m

$254

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

dt. 6/2

5:21 pm-11:54 pm

1 stop5h 33m

Buffalo

dc. 6/10

10:44 am-4:38 pm

1 stop6h 54m

$263

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

dl. 8/10

7:00 am-11:58 pm

1 stop15h 58m

Buffalo

dc. 8/19

7:40 pm-9:27 am

1 stop14h 47m

$267

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

dt. 6/9

12:39 pm-6:27 pm

1 stop4h 48m

Buffalo

dc. 6/17

12:14 pm-8:56 pm

1 stop9h 42m

$276
Quickest round-trip

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

ds. 4/18

6:30 am-1:13 pm

1 stop5h 43m

Buffalo

ds. 4/25

7:00 am-10:45 am

1 stop4h 45m

$297

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

ds. 4/18

8:21 am-6:13 pm

2 stops8h 52m

Buffalo

ds. 4/25

7:00 am-10:45 am

1 stop4h 45m

$302

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

dj. 4/23

6:00 am-2:21 pm

1 stop7h 21m

Buffalo

ds. 4/25

6:00 pm-9:30 pm

1 stop4h 30m

$318

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from Missouri to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of July, then book flights to Buffalo from Missouri during September instead. Flights to Buffalo in September, while not as cheap as those in July, still average around $316.

Cheap Missouri to Buffalo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Buffalo

Fastest flight time

3h 40m

Direct flights

None
The fastest flight from Missouri to Buffalo takes 3h 40m
There are no direct flights from Missouri to Buffalo. There are no popular flight routes from Missouri to Buffalo.
Search flight deals

  • When did momondo last update prices for flights from Missouri to Buffalo Airport?

    Prices for flights from Missouri to Buffalo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Missouri to Buffalo Airport?

  • How old do you have to be to fly from Missouri to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Missouri to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents you'll need for your trip to Buffalo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Buffalo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Missouri to Buffalo

Compare and see reviews for airlines that fly from Missouri to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $167Free CancellationRating
7.4
9,469 reviews
Search United Airlines flights
American AirlinesPriceFrom $221Free CancellationRating
7.1
11,492 reviews
Search American Airlines flights
DeltaPriceFrom $233Free CancellationRating
7.9
8,320 reviews
Search Delta flights
SouthwestPriceFrom $296Free CancellationRating
8.0
4,329 reviews
Search Southwest flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Tonawanda
Grand Island
Orchard Park
Williamsville
Lockport
West Seneca
Bowmansville
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Buffalo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Missouri to Buffalo for you.

Can I find flights from Missouri to Buffalo with flexible booking policies on momondo?

Flights from Missouri to Buffalo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Missouri to Buffalo?

momondo helps you find the best flight between Missouri and Buffalo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Buffalo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Buffalo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
dj. 4/23
dj. 4/30
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