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Cheap flights from Missouri to Buffalo from $159

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Buffalo departing on 3/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Missouri to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:24 pm - 10:49 am
MCI
-
BUF
21h 25m
2 stops
Multiple Airlines Logo
8:16 pm - 11:53 pm
BUF
-
MCI
28h 37m
1 stop
$246Multiple Airlines
Tue, Mar 31 - Mon, Apr 13
Multiple Airlines Logo
8:40 pm - 11:05 am
MCI
-
BUF
13h 25m
2 stops
Multiple Airlines Logo
9:25 pm - 3:29 pm
BUF
-
MCI
19h 04m
1 stop
$254Multiple Airlines
Sat, Mar 7 - Mon, Mar 9
Frontier Logo
11:45 am - 12:05 pm
MCI
-
BUF
23h 20m
1 stop
Frontier Logo
11:59 am - 5:25 pm
BUF
-
MCI
6h 26m
1 stop
$255Frontier
Wed, Mar 11 - Mon, Mar 16
Multiple Airlines Logo
5:45 am - 10:49 am
MCI
-
BUF
28h 04m
1 stop
Multiple Airlines Logo
8:16 pm - 11:53 pm
BUF
-
MCI
28h 37m
1 stop
$262Multiple Airlines
Tue, Mar 31 - Mon, Apr 13
Frontier Logo
11:45 am - 12:05 pm
MCI
-
BUF
23h 20m
1 stop
Frontier Logo
12:45 pm - 5:25 pm
BUF
-
MCI
29h 40m
1 stop
$266Frontier
Wed, Mar 11 - Sun, Mar 15
American Airlines Logo
5:19 am - 10:50 am
SGF
-
BUF
4h 31m
1 stop
American Airlines Logo
6:00 am - 9:51 am
BUF
-
SGF
4h 51m
1 stop
$269American Airlines
Wed, Apr 22 - Wed, Apr 29
United Airlines Logo
3:23 pm - 8:43 pm
COU
-
BUF
4h 20m
1 stop
United Airlines Logo
5:50 pm - 9:58 pm
BUF
-
COU
5h 08m
1 stop
$328United Airlines
Tue, Apr 28 - Sat, May 2
United Airlines Logo
3:23 pm - 8:43 pm
COU
-
BUF
4h 20m
1 stop
United Airlines Logo
6:00 am - 2:32 pm
BUF
-
COU
9h 32m
2 stops
$334United Airlines
Tue, Apr 28 - Sat, May 2
Delta Logo
10:12 am - 5:37 pm
STL
-
BUF
6h 25m
1 stop
Delta Logo
7:38 pm - 11:58 pm
BUF
-
STL
5h 20m
1 stop
$342Delta
Wed, Mar 11 - Mon, Mar 16
American Airlines Logo
5:19 am - 10:50 am
SGF
-
BUF
4h 31m
1 stop
American Airlines Logo
7:25 am - 2:43 pm
BUF
-
SGF
8h 18m
2 stops
$380American Airlines
Wed, Apr 22 - Wed, Apr 29

American Airlines flights from Missouri to Buffalo

Our best American Airlines deals on Missouri to Buffalo flight tickets
American Airlines
Apr 22
SGF5:19 amSpringfield-Branson
4h 31m
1 stop
BUF10:50 amBuffalo
Apr 29
BUF6:00 amBuffalo
4h 51m
1 stop
SGF9:51 amSpringfield-Branson
$269
American Airlines
Mar 25
MCI6:00 amKansas City
8h 25m
2 stops
BUF3:25 pmBuffalo
Apr 1
BUF7:40 pmBuffalo
5h 19m
1 stop
MCI11:59 pmKansas City
$369
American Airlines
Apr 22
SGF5:19 amSpringfield-Branson
4h 31m
1 stop
BUF10:50 amBuffalo
Apr 29
BUF7:25 amBuffalo
8h 18m
2 stops
SGF2:43 pmSpringfield-Branson
$380

United Airlines flights from Missouri to Buffalo

Our best United Airlines deals on Missouri to Buffalo flight tickets
United Airlines
Apr 28
COU3:23 pmColumbia Regional
4h 20m
1 stop
BUF8:43 pmBuffalo
May 2
BUF5:50 pmBuffalo
5h 08m
1 stop
COU9:58 pmColumbia Regional
$328
United Airlines
Apr 28
COU3:23 pmColumbia Regional
4h 20m
1 stop
BUF8:43 pmBuffalo
May 2
BUF6:00 amBuffalo
9h 32m
2 stops
COU2:32 pmColumbia Regional
$334
United Airlines
Apr 28
COU11:30 amColumbia Regional
11h 20m
2 stops
BUF11:50 pmBuffalo
May 2
BUF6:00 amBuffalo
9h 32m
2 stops
COU2:32 pmColumbia Regional
$339

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Missouri to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Tue 3/31

12:24 pm-10:49 am

2 stops21h 25m

Buffalo

Mon 4/13

8:16 pm-11:53 pm

1 stop28h 37m

$246

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Sat 3/7

8:40 pm-11:05 am

2 stops13h 25m

Buffalo

Mon 3/9

9:25 pm-3:29 pm

1 stop19h 04m

$254

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Wed 3/11

11:45 am-12:05 pm

1 stop23h 20m

Buffalo

Mon 3/16

11:59 am-5:25 pm

1 stop6h 26m

$255

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Tue 3/31

5:45 am-10:49 am

1 stop28h 04m

Buffalo

Mon 4/13

8:16 pm-11:53 pm

1 stop28h 37m

$262

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Wed 3/11

11:45 am-12:05 pm

1 stop23h 20m

Buffalo

Sun 3/15

12:45 pm-5:25 pm

1 stop29h 40m

$266

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Wed 4/22

5:19 am-10:50 am

1 stop4h 31m

Buffalo

Wed 4/29

6:00 am-9:51 am

1 stop4h 51m

$269

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

Tue 4/28

3:23 pm-8:43 pm

1 stop4h 20m

Buffalo

Sat 5/2

5:50 pm-9:58 pm

1 stop5h 08m

$328

ColumbiaBuffalo

COU - BUF

COUBUF

Columbia Regional

Tue 4/28

3:23 pm-8:43 pm

1 stop4h 20m

Buffalo

Sat 5/2

6:00 am-2:32 pm

2 stops9h 32m

$334

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Wed 3/11

10:12 am-5:37 pm

1 stop6h 25m

Buffalo

Mon 3/16

7:38 pm-11:58 pm

1 stop5h 20m

$342

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Wed 4/22

5:19 am-10:50 am

1 stop4h 31m

Buffalo

Wed 4/29

7:25 am-2:43 pm

2 stops8h 18m

$380

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from Missouri to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of November, then book flights to Buffalo from Missouri during October instead. Flights to Buffalo in October, while not as cheap as those in November, still average around $344.

How far in advance should I book a flight to Buffalo?

You are more likely to see cheaper flights to Buffalo from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Buffalo for around $383 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Buffalo from Missouri for as low as $285 on momondo.

Cheap Missouri to Buffalo flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Buffalo

Fastest flight time

3h 50m

Direct flights

Fri

Airports in Buffalo

1 airport
The fastest flight from Missouri to Buffalo takes 3h 50m
Direct flights go from Missouri to Buffalo on Friday. There are no airlines offering direct flights.
There is 1 airport in Buffalo. From Missouri there are direct flights to Buffalo (BUF).
Search flight deals

  • When did momondo last update prices for flights from Missouri to Buffalo Airport?

    Prices for flights from Missouri to Buffalo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Missouri to Buffalo Airport?

  • How old do you have to be to fly from Missouri to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Missouri to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The travel and health documents you'll need for your trip to Buffalo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Buffalo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Missouri to Buffalo?

Best airlines flying from Missouri to Buffalo

Compare and see reviews for airlines that fly from Missouri to Buffalo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $143Free CancellationRating
7.9
8,144 reviews
Search Delta flights
United AirlinesPriceFrom $167Free CancellationRating
7.4
9,236 reviews
Search United Airlines flights
American AirlinesPriceFrom $221Free CancellationRating
7.2
11,222 reviews
Search American Airlines flights
SouthwestPriceFrom $296Free CancellationRating
8.0
4,274 reviews
Search Southwest flights

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Grand Island
Tonawanda
Williamsville
Orchard Park
Lockport
West Seneca
Bowmansville
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Buffalo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Missouri to Buffalo for you.

Can I find flights from Missouri to Buffalo with flexible booking policies on momondo?

Flights from Missouri to Buffalo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Missouri to Buffalo?

momondo helps you find the best flight between Missouri and Buffalo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Buffalo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Buffalo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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