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Cheap flights from Milwaukee to Florence from $309

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Milwaukee to Florence departing on 4/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Milwaukee to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:29 pm - 10:42 pm
MKE
-
FLO
4h 13m
1 stop
American Airlines Logo
4:02 pm - 9:57 pm
FLO
-
MKE
6h 55m
1 stop
$309American Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
6:00 am - 3:32 pm
MKE
-
FLO
8h 32m
2 stops
American Airlines Logo
4:02 pm - 9:57 pm
FLO
-
MKE
6h 55m
1 stop
$314American Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
5:06 am - 3:32 pm
MKE
-
FLO
9h 26m
2 stops
American Airlines Logo
4:02 pm - 10:00 pm
FLO
-
MKE
6h 58m
2 stops
$319American Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
6:37 pm - 11:57 pm
MKE
-
FLO
4h 20m
1 stop
American Airlines Logo
5:20 am - 11:30 am
FLO
-
MKE
7h 10m
1 stop
$413American Airlines
Mon, Apr 6 - Fri, Apr 10
American Airlines Logo
6:37 pm - 11:57 pm
MKE
-
FLO
4h 20m
1 stop
American Airlines Logo
5:20 am - 1:23 pm
FLO
-
MKE
9h 03m
2 stops
$418American Airlines
Mon, Apr 6 - Fri, Apr 10
American Airlines Logo
4:47 pm - 11:57 pm
MKE
-
FLO
6h 10m
2 stops
American Airlines Logo
4:16 pm - 11:40 pm
FLO
-
MKE
8h 24m
2 stops
$423American Airlines
Mon, Apr 6 - Fri, Apr 10
American Airlines Logo
11:13 am - 9:47 pm
MKE
-
FLO
9h 34m
2 stops
American Airlines Logo
4:16 pm - 11:29 pm
FLO
-
MKE
8h 13m
2 stops
$647American Airlines
Mon, Apr 20 - Mon, Apr 27
American Airlines Logo
11:13 am - 9:47 pm
MKE
-
FLO
9h 34m
2 stops
American Airlines Logo
5:20 am - 11:30 am
FLO
-
MKE
7h 10m
1 stop
$779American Airlines
Mon, Apr 20 - Mon, Apr 27
American Airlines Logo
6:41 pm - 3:32 pm
MKE
-
FLO
19h 51m
1 stop
American Airlines Logo
4:16 pm - 10:09 am
FLO
-
MKE
18h 53m
1 stop
$855American Airlines
Mon, Apr 20 - Mon, Apr 27

American Airlines flights from Milwaukee to Florence, South Carolina

Our best American Airlines deals on Milwaukee to Florence, South Carolina flight tickets
American Airlines
Apr 21
MKE5:29 pmMilwaukee-Mitchell
4h 13m
1 stop
FLO10:42 pmFlorence
Apr 28
FLO4:02 pmFlorence
6h 55m
1 stop
MKE9:57 pmMilwaukee-Mitchell
$309
American Airlines
Apr 21
MKE6:00 amMilwaukee-Mitchell
8h 32m
2 stops
FLO3:32 pmFlorence
Apr 28
FLO4:02 pmFlorence
6h 55m
1 stop
MKE9:57 pmMilwaukee-Mitchell
$314
American Airlines
Apr 21
MKE5:06 amMilwaukee-Mitchell
9h 26m
2 stops
FLO3:32 pmFlorence
Apr 28
FLO4:02 pmFlorence
6h 58m
2 stops
MKE10:00 pmMilwaukee-Mitchell
$319

momondo Fare Finder

 
Customize your flight search to find flights from Milwaukee to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Milwaukee to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Tue 4/21

5:29 pm-10:42 pm

1 stop4h 13m

Florence

Tue 4/28

4:02 pm-9:57 pm

1 stop6h 55m

$309

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Tue 4/21

6:00 am-3:32 pm

2 stops8h 32m

Florence

Tue 4/28

4:02 pm-9:57 pm

1 stop6h 55m

$314

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Tue 4/21

5:06 am-3:32 pm

2 stops9h 26m

Florence

Tue 4/28

4:02 pm-10:00 pm

2 stops6h 58m

$319

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Mon 4/6

6:37 pm-11:57 pm

1 stop4h 20m

Florence

Fri 4/10

5:20 am-11:30 am

1 stop7h 10m

$413

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Mon 4/6

6:37 pm-11:57 pm

1 stop4h 20m

Florence

Fri 4/10

5:20 am-1:23 pm

2 stops9h 03m

$418

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Mon 4/6

4:47 pm-11:57 pm

2 stops6h 10m

Florence

Fri 4/10

4:16 pm-11:40 pm

2 stops8h 24m

$423

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Mon 4/20

11:13 am-9:47 pm

2 stops9h 34m

Florence

Mon 4/27

4:16 pm-11:29 pm

2 stops8h 13m

$647

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Mon 4/20

11:13 am-9:47 pm

2 stops9h 34m

Florence

Mon 4/27

5:20 am-11:30 am

1 stop7h 10m

$779

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Mon 4/20

6:41 pm-3:32 pm

1 stop19h 51m

Florence

Mon 4/27

4:16 pm-10:09 am

1 stop18h 53m

$855

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Milwaukee to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, United Airlines and Frontier are the top three most popular airlines that fly to Florence, South Carolina from Milwaukee according to our data. American Airlines is the first choice among our users, with 58% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 6 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Milwaukee to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Milwaukee to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Milwaukee to Florence, South Carolina (MKE to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to Florence, South Carolina

Fastest flight time

4h 13m

Direct flights

None
The fastest flight from Milwaukee to Florence, South Carolina takes 4h 13m
There are no direct flights from Milwaukee to Florence, South Carolina. There are no popular flight routes from Milwaukee to Florence, South Carolina.
Search flight deals

  • How far is Milwaukee-Mitchell to Florence by plane?

    Milwaukee-Mitchell and Florence are 751.4 mi apart from one another. A reasonable flight in good conditions will take 4h 13m.

  • When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Florence Airport?

    Prices for flights from Milwaukee-Mitchell Airport to Florence Airport are updated daily.

  • How old do you have to be to fly from Milwaukee-Mitchell Airport to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Milwaukee-Mitchell Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to Florence?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Milwaukee to Florence. momondo saves you time and could save you money on your trip.

Can I find flights from Milwaukee to Florence with flexible booking policies on momondo?

All flight searches from Milwaukee to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Milwaukee to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Milwaukee to Florence.

I’m not ready to book a flight from Milwaukee to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Milwaukee to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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