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Cheap flights from Milwaukee to Florence from $325

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Milwaukee to Florence departing on 1/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Milwaukee to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
4:05 pm - 11:11 pm
MKE
-
FLO
6h 06m1 stop
American Airlines Logo
5:36 pm - 11:23 pm
FLO
-
MKE
6h 47m1 stop
$325American Airlines
Sat, Jan 10 - Wed, Jan 14
American Airlines Logo
4:05 pm - 11:11 pm
MKE
-
FLO
6h 06m1 stop
American Airlines Logo
6:15 am - 5:05 pm
FLO
-
MKE
11h 50m2 stops
$330American Airlines
Sat, Jan 10 - Wed, Jan 14
American Airlines Logo
6:00 am - 5:09 pm
MKE
-
FLO
10h 09m2 stops
American Airlines Logo
6:15 am - 5:05 pm
FLO
-
MKE
11h 50m2 stops
$335American Airlines
Sat, Jan 10 - Wed, Jan 14

American Airlines flights from Milwaukee to Florence, South Carolina

Our best American Airlines deals on Milwaukee to Florence, South Carolina flight tickets
American Airlines
Jan 10
MKE4:05 pmMilwaukee-Mitchell
6h 06m
1 stop
FLO11:11 pmFlorence
Jan 14
FLO5:36 pmFlorence
6h 47m
1 stop
MKE11:23 pmMilwaukee-Mitchell
$325
Find similar
American Airlines
Jan 10
MKE4:05 pmMilwaukee-Mitchell
6h 06m
1 stop
FLO11:11 pmFlorence
Jan 14
FLO6:15 amFlorence
11h 50m
2 stops
MKE5:05 pmMilwaukee-Mitchell
$330
Find similar
American Airlines
Jan 10
MKE6:00 amMilwaukee-Mitchell
10h 09m
2 stops
FLO5:09 pmFlorence
Jan 14
FLO6:15 amFlorence
11h 50m
2 stops
MKE5:05 pmMilwaukee-Mitchell
$335
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Milwaukee to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Milwaukee to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Sat 1/10

4:05 pm-11:11 pm

1 stop6h 06m

Florence

Wed 1/14

5:36 pm-11:23 pm

1 stop6h 47m

$325

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Sat 1/10

4:05 pm-11:11 pm

1 stop6h 06m

Florence

Wed 1/14

6:15 am-5:05 pm

2 stops11h 50m

$330

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Sat 1/10

6:00 am-5:09 pm

2 stops10h 09m

Florence

Wed 1/14

6:15 am-5:05 pm

2 stops11h 50m

$335

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Milwaukee to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the morning. momondo users have found flights departing from Milwaukee to Florence, South Carolina in the morning for as low as $360. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the afternoon is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $378 per ticket.

When to book flights from Milwaukee to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Milwaukee to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Milwaukee to Florence, South Carolina (MKE to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to Florence, South Carolina

Fastest flight time

6h 06m

Direct flights

None
The fastest flight from Milwaukee to Florence, South Carolina takes 6h 06m
There are no direct flights from Milwaukee to Florence, South Carolina. There are no popular flight routes from Milwaukee to Florence, South Carolina.
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  • How far is Milwaukee-Mitchell to Florence by plane?

    Milwaukee-Mitchell and Florence are 751.4 mi apart from one another. A reasonable flight in good conditions will take 6h 06m.

  • When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Florence Airport?

    Prices for flights from Milwaukee-Mitchell Airport to Florence Airport are updated daily.

  • How old do you have to be to fly from Milwaukee-Mitchell Airport to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Milwaukee-Mitchell Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to Florence?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Milwaukee to Florence. momondo saves you time and could save you money on your trip.

Can I find flights from Milwaukee to Florence with flexible booking policies on momondo?

All flight searches from Milwaukee to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Milwaukee to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Milwaukee to Florence.

I’m not ready to book a flight from Milwaukee to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Milwaukee to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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