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Cheap flights from Michigan to Florence from $345

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Michigan to Florence departing on 8/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Michigan to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:49 am - 2:56 pm
ORD
-
FLO
7h 07m
1 stop
American Airlines Logo
6:22 am - 12:15 pm
FLO
-
ORD
6h 53m
1 stop
$345American Airlines
Mon, Aug 10 - Wed, Aug 12
American Airlines Logo
7:30 am - 2:56 pm
ORD
-
FLO
6h 26m
1 stop
American Airlines Logo
3:22 pm - 7:46 pm
FLO
-
ORD
5h 24m
1 stop
$346American Airlines
Mon, Aug 24 - Mon, Aug 31
American Airlines Logo
5:49 pm - 10:59 pm
ORD
-
FLO
4h 10m
1 stop
American Airlines Logo
6:22 am - 12:15 pm
FLO
-
ORD
6h 53m
1 stop
$390American Airlines
Wed, Aug 5 - Wed, Aug 12
American Airlines Logo
5:32 am - 1:18 pm
FNT
-
FLO
7h 46m
2 stops
American Airlines Logo
6:34 am - 5:06 pm
FLO
-
FNT
10h 32m
2 stops
$393American Airlines
Tue, Sep 29 - Tue, Oct 6
American Airlines Logo
7:30 am - 2:12 pm
ORD
-
FLO
5h 42m
1 stop
American Airlines Logo
5:05 am - 9:05 am
FLO
-
ORD
5h 00m
1 stop
$413American Airlines
Sun, Aug 9 - Sun, Aug 16
American Airlines Logo
8:54 am - 2:56 pm
ORD
-
FLO
5h 02m
1 stop
American Airlines Logo
3:22 pm - 7:46 pm
FLO
-
ORD
5h 24m
1 stop
$444American Airlines
Thu, Aug 6 - Wed, Aug 12
American Airlines Logo
6:30 am - 2:10 pm
ORD
-
FLO
6h 40m
1 stop
American Airlines Logo
5:17 am - 9:02 am
FLO
-
ORD
4h 45m
1 stop
$458American Airlines
Sun, Jul 26 - Tue, Jul 28
American Airlines Logo
6:00 am - 2:56 pm
LAN
-
FLO
8h 56m
2 stops
American Airlines Logo
3:22 pm - 11:26 pm
FLO
-
LAN
8h 04m
2 stops
$491American Airlines
Fri, Aug 7 - Fri, Aug 14
American Airlines Logo
6:43 pm - 10:59 pm
DTW
-
FLO
4h 16m
1 stop
American Airlines Logo
3:22 pm - 10:30 pm
FLO
-
DTW
7h 08m
1 stop
$518American Airlines
Sat, Aug 8 - Fri, Aug 14
American Airlines Logo
1:30 pm - 12:03 am
DTW
-
FLO
10h 33m
2 stops
American Airlines Logo
5:15 am - 9:48 am
FLO
-
DTW
4h 33m
1 stop
$527American Airlines
Fri, Dec 11 - Wed, Dec 16

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American Airlines flights from Michigan to Florence, South Carolina

Our best American Airlines deals on Michigan to Florence, South Carolina flight tickets
American Airlines
Aug 10
ORD6:49 amChicago O'Hare Intl
7h 07m
1 stop
FLO2:56 pmFlorence
Aug 12
FLO6:22 amFlorence
6h 53m
1 stop
ORD12:15 pmChicago O'Hare Intl
$345
American Airlines
Aug 6
ORD7:30 amChicago O'Hare Intl
6h 26m
1 stop
FLO2:56 pmFlorence
Aug 12
FLO6:22 amFlorence
6h 53m
1 stop
ORD12:15 pmChicago O'Hare Intl
$346
American Airlines
Aug 5
ORD5:49 pmChicago O'Hare Intl
4h 10m
1 stop
FLO10:59 pmFlorence
Aug 12
FLO6:22 amFlorence
6h 53m
1 stop
ORD12:15 pmChicago O'Hare Intl
$390

momondo Fare Finder

 
Customize your flight search to find flights from Michigan to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 11, 2026.
Use the filters below to find and compare flights from Michigan to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Mon 8/10

6:49 am-2:56 pm

1 stop7h 07m

Florence

Wed 8/12

6:22 am-12:15 pm

1 stop6h 53m

$345

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Mon 8/24

7:30 am-2:56 pm

1 stop6h 26m

Florence

Mon 8/31

3:22 pm-7:46 pm

1 stop5h 24m

$346

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Wed 8/5

5:49 pm-10:59 pm

1 stop4h 10m

Florence

Wed 8/12

6:22 am-12:15 pm

1 stop6h 53m

$390

FlintFlorence

FNT - FLO

FNTFLO

Flint Bishop

Tue 9/29

5:32 am-1:18 pm

2 stops7h 46m

Florence

Tue 10/6

6:34 am-5:06 pm

2 stops10h 32m

$393

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Sun 8/9

7:30 am-2:12 pm

1 stop5h 42m

Florence

Sun 8/16

5:05 am-9:05 am

1 stop5h 00m

$413
Quickest round-trip

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Thu 8/6

8:54 am-2:56 pm

1 stop5h 02m

Florence

Wed 8/12

3:22 pm-7:46 pm

1 stop5h 24m

$444

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

Sun 7/26

6:30 am-2:10 pm

1 stop6h 40m

Florence

Tue 7/28

5:17 am-9:02 am

1 stop4h 45m

$458

LansingFlorence

LAN - FLO

LANFLO

Lansing Capital City

Fri 8/7

6:00 am-2:56 pm

2 stops8h 56m

Florence

Fri 8/14

3:22 pm-11:26 pm

2 stops8h 04m

$491

DetroitFlorence

DTW - FLO

DTWFLO

Detroit Metropolitan Wayne County

Sat 8/8

6:43 pm-10:59 pm

1 stop4h 16m

Florence

Fri 8/14

3:22 pm-10:30 pm

1 stop7h 08m

$518

DetroitFlorence

DTW - FLO

DTWFLO

Detroit Metropolitan Wayne County

Fri 12/11

1:30 pm-12:03 am

2 stops10h 33m

Florence

Wed 12/16

5:15 am-9:48 am

1 stop4h 33m

$527

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Michigan to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Michigan to Florence, South Carolina flights?

You could potentially save up to 34% on your flight if you consider stops on a Michigan to Florence, South Carolina flight.

Cheap Michigan to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Michigan to Florence, South Carolina

Fastest flight time

3h 39m

Direct flights

None
The fastest flight from Michigan to Florence, South Carolina takes 3h 39m
There are no direct flights from Michigan to Florence, South Carolina. There are no popular flight routes from Michigan to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Michigan to Florence, South Carolina

  • When did momondo last update prices for flights from Michigan to Florence Airport?

    Prices for flights from Michigan to Florence Airport are updated daily.

  • How old do you have to be to fly from Michigan to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Michigan to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Michigan to Florence?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Michigan to Florence for you.

Can I find flights from Michigan to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Michigan which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Michigan to Florence?

Once you have performed a search for Michigan to Florence flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Michigan to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Michigan to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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