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Cheap flights from Michigan to Florence from $335

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Michigan to Florence departing on 1/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Michigan to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:17 pm - 10:43 pm
DTW
-
FLO
4h 26m1 stop
American Airlines Logo
5:36 pm - 11:56 pm
FLO
-
DTW
6h 20m1 stop
$335American Airlines
wt., sty 6 - sob., sty 10
American Airlines Logo
8:00 am - 5:09 pm
DTW
-
FLO
9h 09m2 stops
American Airlines Logo
6:15 am - 12:11 pm
FLO
-
DTW
5h 56m1 stop
$340American Airlines
wt., sty 6 - sob., sty 10
American Airlines Logo
8:00 am - 5:09 pm
DTW
-
FLO
9h 09m2 stops
American Airlines Logo
6:15 am - 1:32 pm
FLO
-
DTW
7h 17m2 stops
$345American Airlines
wt., sty 6 - sob., sty 10
American Airlines Logo
10:10 am - 5:09 pm
ORD
-
FLO
5h 59m1 stop
American Airlines Logo
5:36 pm - 11:27 pm
FLO
-
ORD
6h 51m1 stop
$370American Airlines
pt., sty 16 - pon., sty 19
American Airlines Logo
3:21 pm - 10:43 pm
ORD
-
FLO
6h 22m1 stop
American Airlines Logo
6:15 am - 2:01 pm
FLO
-
ORD
8h 46m2 stops
$375American Airlines
pt., sty 16 - pon., sty 19
American Airlines Logo
7:00 am - 2:10 pm
ORD
-
FLO
6h 10m1 stop
American Airlines Logo
5:13 am - 8:49 am
FLO
-
ORD
4h 36m1 stop
$390American Airlines
wt., kwi 7 - ndz., kwi 12
American Airlines Logo
6:45 am - 2:10 pm
ORD
-
FLO
6h 25m2 stops
American Airlines Logo
5:13 am - 8:49 am
FLO
-
ORD
4h 36m1 stop
$395American Airlines
wt., kwi 7 - ndz., kwi 12
American Airlines Logo
6:48 pm - 10:43 pm
GRR
-
FLO
3h 55m1 stop
American Airlines Logo
5:36 pm - 11:56 pm
FLO
-
GRR
6h 20m1 stop
$481American Airlines
wt., sty 6 - sob., sty 10
American Airlines Logo
6:48 pm - 10:43 pm
GRR
-
FLO
3h 55m1 stop
American Airlines Logo
6:15 am - 3:27 pm
FLO
-
GRR
9h 12m2 stops
$486American Airlines
wt., sty 6 - sob., sty 10
American Airlines Logo
12:18 pm - 10:43 pm
GRR
-
FLO
10h 25m2 stops
American Airlines Logo
6:15 am - 2:36 pm
FLO
-
GRR
8h 21m2 stops
$491American Airlines
wt., sty 6 - sob., sty 10

American Airlines flights from Michigan to Florence, South Carolina

Our best American Airlines deals on Michigan to Florence, South Carolina flight tickets
American Airlines
Jan 6
DTW6:17 pmDetroit Metropolitan Wayne County
4h 26m
1 stop
FLO10:43 pmFlorence
Jan 10
FLO5:36 pmFlorence
6h 20m
1 stop
DTW11:56 pmDetroit Metropolitan Wayne County
$335
Find similar
American Airlines
Jan 6
DTW8:00 amDetroit Metropolitan Wayne County
9h 09m
2 stops
FLO5:09 pmFlorence
Jan 10
FLO6:15 amFlorence
5h 56m
1 stop
DTW12:11 pmDetroit Metropolitan Wayne County
$340
Find similar
American Airlines
Jan 6
DTW8:00 amDetroit Metropolitan Wayne County
9h 09m
2 stops
FLO5:09 pmFlorence
Jan 10
FLO6:15 amFlorence
7h 17m
2 stops
DTW1:32 pmDetroit Metropolitan Wayne County
$345
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Michigan to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated Grudzień 22, 2025.
Use the filters below to find and compare flights from Michigan to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitFlorence

DTW - FLO

DTWFLO

Detroit Metropolitan Wayne County

wt. 1/6

6:17 pm-10:43 pm

1 stop4h 26m

Florence

sob. 1/10

5:36 pm-11:56 pm

1 stop6h 20m

$335

DetroitFlorence

DTW - FLO

DTWFLO

Detroit Metropolitan Wayne County

wt. 1/6

8:00 am-5:09 pm

2 stops9h 09m

Florence

sob. 1/10

6:15 am-12:11 pm

1 stop5h 56m

$340

DetroitFlorence

DTW - FLO

DTWFLO

Detroit Metropolitan Wayne County

wt. 1/6

8:00 am-5:09 pm

2 stops9h 09m

Florence

sob. 1/10

6:15 am-1:32 pm

2 stops7h 17m

$345

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

pt. 1/16

10:10 am-5:09 pm

1 stop5h 59m

Florence

pon. 1/19

5:36 pm-11:27 pm

1 stop6h 51m

$370

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

pt. 1/16

3:21 pm-10:43 pm

1 stop6h 22m

Florence

pon. 1/19

6:15 am-2:01 pm

2 stops8h 46m

$375

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

wt. 4/7

7:00 am-2:10 pm

1 stop6h 10m

Florence

ndz. 4/12

5:13 am-8:49 am

1 stop4h 36m

$390

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

wt. 4/7

6:45 am-2:10 pm

2 stops6h 25m

Florence

ndz. 4/12

5:13 am-8:49 am

1 stop4h 36m

$395

Grand RapidsFlorence

GRR - FLO

GRRFLO

Grand Rapids Gerald R. Ford Intl

wt. 1/6

6:48 pm-10:43 pm

1 stop3h 55m

Florence

sob. 1/10

5:36 pm-11:56 pm

1 stop6h 20m

$481

Grand RapidsFlorence

GRR - FLO

GRRFLO

Grand Rapids Gerald R. Ford Intl

wt. 1/6

6:48 pm-10:43 pm

1 stop3h 55m

Florence

sob. 1/10

6:15 am-3:27 pm

2 stops9h 12m

$486

Grand RapidsFlorence

GRR - FLO

GRRFLO

Grand Rapids Gerald R. Ford Intl

wt. 1/6

12:18 pm-10:43 pm

2 stops10h 25m

Florence

sob. 1/10

6:15 am-2:36 pm

2 stops8h 21m

$491

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Michigan to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from Michigan is on a Thursday. momondo users have found tickets for Thursday departures for as low as $360. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Friday is the most expensive day to depart from Michigan because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $387.

Cheap Michigan to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Michigan to Florence, South Carolina

Fastest flight time

3h 55m

Direct flights

None
The fastest flight from Michigan to Florence, South Carolina takes 3h 55m
There are no direct flights from Michigan to Florence, South Carolina. There are no popular flight routes from Michigan to Florence, South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Michigan to Florence Airport?

    Prices for flights from Michigan to Florence Airport are updated daily.

  • How many operators does momondo search for flights from Michigan to Florence Airport?

  • How old do you have to be to fly from Michigan to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Michigan to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Michigan to Florence?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Michigan to Florence for you.

Can I find flights from Michigan to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Michigan which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Michigan to Florence?

Once you have performed a search for Michigan to Florence flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Michigan to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Michigan to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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