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Cheap flights from Medford to South Carolina from $329

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Medford to South Carolina departing on 1/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Medford to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 pm - 6:11 am
MFR
-
CLT
9h 11m1 stop
American Airlines Logo
7:45 am - 1:07 pm
CLT
-
MFR
8h 22m1 stop
$329American Airlines
Sun, Jan 11 - Sun, Jan 25
Delta Logo
5:20 pm - 9:18 am
MFR
-
CLT
12h 58m2 stops
Delta Logo
5:10 pm - 11:48 pm
CLT
-
MFR
9h 38m1 stop
$359Delta
Sun, Jan 11 - Sun, Jan 25
Delta Logo
5:20 pm - 9:18 am
MFR
-
CLT
12h 58m2 stops
Delta Logo
5:25 am - 12:25 pm
CLT
-
MFR
10h 00m2 stops
$364Delta
Sun, Jan 11 - Sun, Jan 25
United Airlines Logo
5:00 am - 11:48 pm
MFR
-
GSP
15h 48m2 stops
United Airlines Logo
4:15 pm - 9:02 pm
GSP
-
MFR
7h 47m1 stop
$410United Airlines
Sat, Jan 10 - Wed, Jan 14
United Airlines Logo
5:00 am - 11:48 pm
MFR
-
GSP
15h 48m2 stops
United Airlines Logo
10:00 am - 9:02 pm
GSP
-
MFR
14h 02m2 stops
$415United Airlines
Sat, Jan 10 - Wed, Jan 14
United Airlines Logo
6:00 am - 11:44 pm
MFR
-
CAE
14h 44m2 stops
United Airlines Logo
10:10 am - 9:02 pm
CAE
-
MFR
13h 52m2 stops
$427United Airlines
Wed, Jan 28 - Sat, Jan 31
United Airlines Logo
5:02 am - 9:21 pm
MFR
-
CLT
13h 19m2 stops
United Airlines Logo
4:25 pm - 9:18 pm
CLT
-
MFR
7h 53m1 stop
$434United Airlines
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
5:02 am - 9:21 pm
MFR
-
CLT
13h 19m2 stops
United Airlines Logo
11:23 am - 10:28 pm
CLT
-
MFR
14h 05m2 stops
$439United Airlines
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
5:00 am - 11:48 pm
MFR
-
GSP
15h 48m2 stops
United Airlines Logo
4:15 pm - 9:02 pm
GSP
-
MFR
7h 47m1 stop
$464United Airlines
Sat, Jan 10 - Wed, Jan 14
United Airlines Logo
5:00 am - 3:20 pm
MFR
-
GSP
7h 20m1 stop
United Airlines Logo
4:15 pm - 9:02 pm
GSP
-
MFR
7h 47m1 stop
$470United Airlines
Sat, Jan 10 - Wed, Jan 14

American Airlines flights from Medford to South Carolina

Our best American Airlines deals on Medford to South Carolina flight tickets
American Airlines
Jan 11
MFR6:00 pmMedford
9h 11m
1 stop
CLT6:11 amCharlotte Douglas
Jan 25
CLT7:45 amCharlotte Douglas
8h 22m
1 stop
MFR1:07 pmMedford
$329
Find similar
American Airlines
Dec 23
MFR5:20 amMedford
8h 55m
1 stop
CLT5:15 pmCharlotte Douglas
Dec 30
CLT1:10 pmCharlotte Douglas
10h 10m
1 stop
MFR8:20 pmMedford
$1,039
Find similar
American Airlines
Dec 23
MFR5:20 amMedford
8h 55m
1 stop
CLT5:15 pmCharlotte Douglas
Dec 30
CLT1:10 pmCharlotte Douglas
10h 10m
1 stop
MFR8:20 pmMedford
$1,086
Find similar

Delta flights from Medford to South Carolina

Our best Delta deals on Medford to South Carolina flight tickets
Delta
Jan 11
MFR5:20 pmMedford
12h 58m
2 stops
CLT9:18 amCharlotte Douglas
Jan 25
CLT5:10 pmCharlotte Douglas
9h 38m
1 stop
MFR11:48 pmMedford
$359
Find similar
Delta
Jan 11
MFR5:20 pmMedford
12h 58m
2 stops
CLT9:18 amCharlotte Douglas
Jan 25
CLT5:25 amCharlotte Douglas
10h 00m
2 stops
MFR12:25 pmMedford
$364
Find similar
Delta
Apr 20
MFR5:21 pmMedford
13h 05m
2 stops
CAE9:26 amColumbia Metropolitan
Apr 22
CAE1:20 pmColumbia Metropolitan
12h 53m
2 stops
MFR11:13 pmMedford
$715
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Medford to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Medford to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Sun 1/11

6:00 pm-6:11 am

1 stop9h 11m

Charlotte Douglas

Sun 1/25

7:45 am-1:07 pm

1 stop8h 22m

$329

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Sun 1/11

5:20 pm-9:18 am

2 stops12h 58m

Charlotte Douglas

Sun 1/25

5:10 pm-11:48 pm

1 stop9h 38m

$359

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Sun 1/11

5:20 pm-9:18 am

2 stops12h 58m

Charlotte Douglas

Sun 1/25

5:25 am-12:25 pm

2 stops10h 00m

$364

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 1/10

5:00 am-11:48 pm

2 stops15h 48m

Greenville

Wed 1/14

4:15 pm-9:02 pm

1 stop7h 47m

$410

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 1/10

5:00 am-11:48 pm

2 stops15h 48m

Greenville

Wed 1/14

10:00 am-9:02 pm

2 stops14h 02m

$415

MedfordColumbia

MFR - CAE

MFRCAE

Medford

Wed 1/28

6:00 am-11:44 pm

2 stops14h 44m

Columbia Metropolitan

Sat 1/31

10:10 am-9:02 pm

2 stops13h 52m

$427

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Sat 2/21

5:02 am-9:21 pm

2 stops13h 19m

Charlotte Douglas

Wed 2/25

4:25 pm-9:18 pm

1 stop7h 53m

$434

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Sat 2/21

5:02 am-9:21 pm

2 stops13h 19m

Charlotte Douglas

Wed 2/25

11:23 am-10:28 pm

2 stops14h 05m

$439

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 1/10

5:00 am-11:48 pm

2 stops15h 48m

Greenville

Wed 1/14

4:15 pm-9:02 pm

1 stop7h 47m

$464

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 1/10

5:00 am-3:20 pm

1 stop7h 20m

Greenville

Wed 1/14

4:15 pm-9:02 pm

1 stop7h 47m

$470

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Medford to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Saturday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $489. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $712.

Can stopping save me money on Medford to South Carolina flights?

You could potentially save up to 66% on your flight if you consider stops on a Medford to South Carolina flight.

Cheap Medford to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to South Carolina

Fastest flight time

7h 55m

Direct flights

None
The fastest flight from Medford to South Carolina takes 7h 55m
There are no direct flights from Medford to South Carolina. There are no popular flight routes from Medford to South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Medford Airport to South Carolina?

    Prices for flights from Medford Airport to South Carolina were last updated today.

  • How many operators does momondo search for flights from Medford Airport to South Carolina?

  • How old do you have to be to fly from Medford Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Medford Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Medford to South Carolina

Compare and see reviews for airlines that fly from Medford to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $234Free CancellationRating
7.4
9,094 reviews
Search United Airlines flights
DeltaPriceFrom $261Free CancellationRating
7.9
8,010 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Medford to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Medford to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Medford to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Medford on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Medford to South Carolina?

Once all potential Medford to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Medford to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Medford to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.

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