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Cheap flights from Medford to South Carolina from $314

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Medford to South Carolina departing on 9/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Medford to South Carolina

Cheap round-trip flights

United Airlines Logo
6:35 pm - 9:30 amMFR-CLT
11h 55m2 stops
United Airlines Logo
4:27 pm - 9:06 pmCLT-MFR
7h 39m1 stop
$314United Airlines
Find Deal
Tue, Sep 23 - Sat, Sep 27
United Airlines Logo
6:35 pm - 9:30 amMFR-CLT
11h 55m2 stops
United Airlines Logo
6:30 am - 1:11 pmCLT-MFR
9h 41m2 stops
$319United Airlines
Find Deal
Tue, Sep 23 - Sat, Sep 27
Delta Logo
5:15 am - 4:19 pmMFR-CLT
8h 04m1 stop
Delta Logo
5:30 pm - 10:37 pmCLT-MFR
8h 07m1 stop
$359Delta
Find Deal
Tue, Sep 23 - Sat, Sep 27
United Airlines Logo
2:13 pm - 8:51 amMFR-GSP
15h 38m3 stops
United Airlines Logo
4:29 pm - 9:06 pmGSP-MFR
7h 37m1 stop
$381United Airlines
Find Deal
Sat, Sep 27 - Sat, Oct 4
United Airlines Logo
2:13 pm - 8:51 amMFR-GSP
15h 38m3 stops
United Airlines Logo
9:35 am - 8:29 pmGSP-MFR
13h 54m2 stops
$386United Airlines
Find Deal
Sat, Sep 27 - Sat, Oct 4
Delta Logo
5:15 am - 4:19 pmMFR-CLT
8h 04m1 stop
Delta Logo
5:30 pm - 10:37 pmCLT-MFR
8h 07m1 stop
$389Delta
Find Deal
Wed, Sep 24 - Sat, Sep 27
Delta Logo
5:15 am - 4:19 pmMFR-CLT
8h 04m1 stop
Delta Logo
5:30 pm - 10:35 pmCLT-MFR
8h 05m1 stop
$393Delta
Find Deal
Wed, Oct 29 - Fri, Oct 31
United Airlines Logo
6:00 am - 11:46 pmMFR-GSP
14h 46m2 stops
United Airlines Logo
4:29 pm - 9:06 pmGSP-MFR
7h 37m1 stop
$395United Airlines
Find Deal
Sat, Sep 27 - Sat, Oct 4
Delta Logo
5:24 pm - 9:16 amMFR-CLT
12h 52m2 stops
Delta Logo
5:30 pm - 10:35 pmCLT-MFR
8h 05m1 stop
$398Delta
Find Deal
Wed, Oct 29 - Fri, Oct 31
Alaska Airlines Logo
7:44 pm - 11:21 amMFR-CLT
12h 37m2 stops
Alaska Airlines Logo
3:30 pm - 11:16 amCLT-MFR
22h 46m2 stops
$669Alaska Airlines
Find Deal
Fri, Oct 10 - Mon, Oct 13

United Airlines flights from Medford to South Carolina

Our best United Airlines deals on Medford to South Carolina flight tickets
United Airlines
Sep 23
MFR6:35 pmMedford
11h 55m
2 stops
CLT9:30 amCharlotte Douglas
Sep 27
CLT4:27 pmCharlotte Douglas
7h 39m
1 stop
MFR9:06 pmMedford
$314
Find similar
United Airlines
Sep 23
MFR6:35 pmMedford
11h 55m
2 stops
CLT9:30 amCharlotte Douglas
Sep 27
CLT6:30 amCharlotte Douglas
9h 41m
2 stops
MFR1:11 pmMedford
$319
Find similar
United Airlines
Sep 27
MFR2:13 pmMedford
15h 38m
3 stops
GSP8:51 amGreenville
Oct 4
GSP4:29 pmGreenville
7h 37m
1 stop
MFR9:06 pmMedford
$381
Find similar

Delta flights from Medford to South Carolina

Our best Delta deals on Medford to South Carolina flight tickets
Delta
Sep 23
MFR5:15 amMedford
8h 04m
1 stop
CLT4:19 pmCharlotte Douglas
Sep 27
CLT5:30 pmCharlotte Douglas
8h 07m
1 stop
MFR10:37 pmMedford
$359
Find similar
Delta
Sep 24
MFR5:15 amMedford
8h 04m
1 stop
CLT4:19 pmCharlotte Douglas
Sep 27
CLT5:30 pmCharlotte Douglas
8h 07m
1 stop
MFR10:37 pmMedford
$389
Find similar
Delta
Oct 29
MFR5:15 amMedford
8h 04m
1 stop
CLT4:19 pmCharlotte Douglas
Oct 31
CLT5:30 pmCharlotte Douglas
8h 05m
1 stop
MFR10:35 pmMedford
$393
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Medford to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 1, 2025.
Use the filters below to find and compare flights from Medford to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Tue 9/23

6:35 pm-9:30 am

2 stops11h 55m

Charlotte Douglas

Sat 9/27

4:27 pm-9:06 pm

1 stop7h 39m

$314

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Tue 9/23

6:35 pm-9:30 am

2 stops11h 55m

Charlotte Douglas

Sat 9/27

6:30 am-1:11 pm

2 stops9h 41m

$319

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Tue 9/23

5:15 am-4:19 pm

1 stop8h 04m

Charlotte Douglas

Sat 9/27

5:30 pm-10:37 pm

1 stop8h 07m

$359

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 9/27

2:13 pm-8:51 am

3 stops15h 38m

Greenville

Sat 10/4

4:29 pm-9:06 pm

1 stop7h 37m

$381

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 9/27

2:13 pm-8:51 am

3 stops15h 38m

Greenville

Sat 10/4

9:35 am-8:29 pm

2 stops13h 54m

$386

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Wed 9/24

5:15 am-4:19 pm

1 stop8h 04m

Charlotte Douglas

Sat 9/27

5:30 pm-10:37 pm

1 stop8h 07m

$389

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Wed 10/29

5:15 am-4:19 pm

1 stop8h 04m

Charlotte Douglas

Fri 10/31

5:30 pm-10:35 pm

1 stop8h 05m

$393

MedfordGreenville

MFR - GSP

MFRGSP

Medford

Sat 9/27

6:00 am-11:46 pm

2 stops14h 46m

Greenville

Sat 10/4

4:29 pm-9:06 pm

1 stop7h 37m

$395

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Wed 10/29

5:24 pm-9:16 am

2 stops12h 52m

Charlotte Douglas

Fri 10/31

5:30 pm-10:35 pm

1 stop8h 05m

$398

MedfordCharlotte

MFR - CLT

MFRCLT

Medford

Fri 10/10

7:44 pm-11:21 am

2 stops12h 37m

Charlotte Douglas

Mon 10/13

3:30 pm-11:16 am

2 stops22h 46m

$669

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to South Carolina from

How to get the cheapest flight ticket from Medford to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Saturday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $489. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $712.

Can stopping save me money on Medford to South Carolina flights?

You could potentially save up to 21% on your flight if you consider stops on a Medford to South Carolina flight.

Cheap Medford to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to South Carolina

Direct flights

None
There are no direct flights from Medford to South Carolina. There are no popular flight routes from Medford to South Carolina.
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  • When did momondo last update prices for flights from Medford Airport to South Carolina?

    Prices for flights from Medford Airport to South Carolina were last updated today.

  • How many operators does momondo search for flights from Medford Airport to South Carolina?

  • How old do you have to be to fly from Medford Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Medford Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Medford to South Carolina

Compare and see reviews for airlines that fly from Medford to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $254Free CancellationRating
7.4
8,936 reviews
Search United Airlines flights
DeltaPriceFrom $274Free CancellationRating
7.9
7,976 reviews
Search Delta flights
Alaska AirlinesPriceFrom $449Free CancellationRating
8.0
10,000 reviews
Search Alaska Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Medford to South Carolina?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Medford to South Carolina. momondo saves you time and could save you money on your trip.

Can I find flights from Medford to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Medford on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Medford to South Carolina?

Once all potential Medford to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Medford to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Medford to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.

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