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Cheap flights from Maryland to Florence from $179

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Maryland to Florence departing on 8/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Maryland to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
9:20 am - 2:10 pm
IAD
-
FLO
4h 50m
1 stop
American Airlines Logo
2:35 pm - 7:33 pm
FLO
-
IAD
4h 58m
1 stop
$269American Airlines
Tue, Jun 2 - Tue, Jun 9
American Airlines Logo
3:20 pm - 10:00 pm
DCA
-
FLO
6h 40m
1 stop
American Airlines Logo
2:35 pm - 6:22 pm
FLO
-
DCA
3h 47m
1 stop
$284American Airlines
Sat, May 23 - Wed, May 27
American Airlines Logo
9:20 am - 2:10 pm
IAD
-
FLO
4h 50m
1 stop
American Airlines Logo
5:05 am - 8:50 am
FLO
-
IAD
3h 45m
1 stop
$284American Airlines
Sat, Jun 6 - Fri, Jun 12
American Airlines Logo
9:51 am - 3:50 pm
DCA
-
FLO
5h 59m
1 stop
American Airlines Logo
5:05 am - 9:29 am
FLO
-
DCA
4h 24m
1 stop
$299American Airlines
Wed, May 20 - Sun, May 24
American Airlines Logo
9:19 am - 3:50 pm
IAD
-
FLO
6h 31m
1 stop
American Airlines Logo
5:05 am - 8:50 am
FLO
-
IAD
3h 45m
1 stop
$299American Airlines
Wed, May 20 - Sun, May 24
American Airlines Logo
6:49 am - 10:21 am
DCA
-
FLO
3h 32m
1 stop
American Airlines Logo
5:31 am - 9:00 am
FLO
-
DCA
3h 29m
1 stop
$328American Airlines
Thu, Sep 24 - Sun, Oct 4
American Airlines Logo
6:58 am - 10:21 am
IAD
-
FLO
3h 23m
1 stop
American Airlines Logo
5:31 am - 8:38 am
FLO
-
IAD
3h 07m
1 stop
$328American Airlines
Thu, Sep 24 - Sun, Oct 4
American Airlines Logo
10:06 am - 2:10 pm
BWI
-
FLO
4h 04m
1 stop
American Airlines Logo
5:05 am - 9:26 am
FLO
-
BWI
4h 21m
1 stop
$347American Airlines
Tue, Jun 2 - Tue, Jun 9
American Airlines Logo
5:26 pm - 10:00 pm
DCA
-
FLO
4h 34m
1 stop
American Airlines Logo
5:05 am - 9:29 am
FLO
-
DCA
4h 24m
1 stop
$354American Airlines
Sat, May 23 - Thu, May 28
American Airlines Logo
8:15 pm - 11:33 pm
BWI
-
FLO
3h 18m
1 stop
American Airlines Logo
5:09 am - 8:33 am
FLO
-
BWI
3h 24m
1 stop
$357American Airlines
Sat, Aug 1 - Thu, Aug 6

American Airlines flights from Maryland to Florence, South Carolina

Our best American Airlines deals on Maryland to Florence, South Carolina flight tickets
American Airlines
Jun 2
IAD9:20 amWashington, D.C. Dulles Intl
4h 50m
1 stop
FLO2:10 pmFlorence
Jun 9
FLO2:35 pmFlorence
4h 58m
1 stop
IAD7:33 pmWashington, D.C. Dulles Intl
$269
American Airlines
Jun 6
IAD9:20 amWashington, D.C. Dulles Intl
4h 50m
1 stop
FLO2:10 pmFlorence
Jun 12
FLO5:05 amFlorence
3h 45m
1 stop
IAD8:50 amWashington, D.C. Dulles Intl
$284
American Airlines
May 20
DCA9:51 amWashington, D.C. Reagan-National
5h 59m
1 stop
FLO3:50 pmFlorence
May 24
FLO5:05 amFlorence
4h 24m
1 stop
DCA9:29 amWashington, D.C. Reagan-National
$299

momondo Fare Finder

 
Customize your flight search to find flights from Maryland to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 8, 2026.
Use the filters below to find and compare flights from Maryland to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

Tue 6/2

9:20 am-2:10 pm

1 stop4h 50m

Florence

Tue 6/9

2:35 pm-7:33 pm

1 stop4h 58m

$269

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 5/23

3:20 pm-10:00 pm

1 stop6h 40m

Florence

Wed 5/27

2:35 pm-6:22 pm

1 stop3h 47m

$284

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

Sat 6/6

9:20 am-2:10 pm

1 stop4h 50m

Florence

Fri 6/12

5:05 am-8:50 am

1 stop3h 45m

$284

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Wed 5/20

9:51 am-3:50 pm

1 stop5h 59m

Florence

Sun 5/24

5:05 am-9:29 am

1 stop4h 24m

$299

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

Wed 5/20

9:19 am-3:50 pm

1 stop6h 31m

Florence

Sun 5/24

5:05 am-8:50 am

1 stop3h 45m

$299

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Thu 9/24

6:49 am-10:21 am

1 stop3h 32m

Florence

Sun 10/4

5:31 am-9:00 am

1 stop3h 29m

$328
Quickest round-trip

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

Thu 9/24

6:58 am-10:21 am

1 stop3h 23m

Florence

Sun 10/4

5:31 am-8:38 am

1 stop3h 07m

$328

BaltimoreFlorence

BWI - FLO

BWIFLO

Baltimore/Washington

Tue 6/2

10:06 am-2:10 pm

1 stop4h 04m

Florence

Tue 6/9

5:05 am-9:26 am

1 stop4h 21m

$347

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 5/23

5:26 pm-10:00 pm

1 stop4h 34m

Florence

Thu 5/28

5:05 am-9:29 am

1 stop4h 24m

$354

BaltimoreFlorence

BWI - FLO

BWIFLO

Baltimore/Washington

Sat 8/1

8:15 pm-11:33 pm

1 stop3h 18m

Florence

Thu 8/6

5:09 am-8:33 am

1 stop3h 24m

$357

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Maryland to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Maryland to Florence?

American Airlines is the most popular carrier operating from Maryland to Florence

What airlines fly to Florence, South Carolina?

Southwest, American Airlines and Frontier are the top three most popular airlines that fly to Florence, South Carolina from Maryland according to our data. Southwest is the first choice among our users, with 41% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 6 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Maryland to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Maryland to Florence, South Carolina

Fastest flight time

3h 23m

Direct flights

None
The fastest flight from Maryland to Florence, South Carolina takes 3h 23m
There are no direct flights from Maryland to Florence, South Carolina. There are no popular flight routes from Maryland to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Maryland to Florence, South Carolina

  • When did momondo last update prices for flights from Maryland to Florence Airport?

    Prices for flights from Maryland to Florence Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Maryland to Florence Airport?

  • How old do you have to be to fly from Maryland to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Maryland to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Maryland to Florence, South Carolina

Compare and see reviews for airlines that fly from Maryland to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $244Free CancellationRating
7.1
11,667 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington
Bennettsville
Lake City

Why use momondo?

Why should I use momondo to find a flight deal from Maryland to Florence?

It is quick and easy to find Maryland to Florence flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florence that suits you.

Can I find flights from Maryland to Florence with flexible booking policies on momondo?

Flights from Maryland to Florence with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Maryland to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Maryland.

I’m not ready to book a flight from Maryland to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Maryland to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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