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Cheap flights from Maryland to Florence from $257

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Maryland to Florence departing on 8/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Maryland to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:35 am - 2:10 pm
PHL
-
FLO
3h 35m
1 stop
American Airlines Logo
6:22 am - 10:56 am
FLO
-
PHL
4h 34m
1 stop
$463American Airlines
Tue, Aug 4 - Tue, Aug 11
American Airlines Logo
1:50 pm - 6:07 pm
PHL
-
FLO
4h 17m
1 stop
American Airlines Logo
11:11 am - 4:39 pm
FLO
-
PHL
5h 28m
1 stop
$511American Airlines
Sat, Nov 14 - Sun, Nov 22
American Airlines Logo
5:50 pm - 11:37 pm
DCA
-
FLO
5h 47m
1 stop
American Airlines Logo
6:22 am - 12:58 pm
FLO
-
DCA
6h 36m
1 stop
$531American Airlines
Tue, Aug 4 - Mon, Aug 10
American Airlines Logo
7:15 pm - 11:57 pm
IAD
-
FLO
4h 42m
1 stop
American Airlines Logo
5:15 am - 8:41 am
FLO
-
IAD
3h 26m
1 stop
$531American Airlines
Fri, Oct 30 - Tue, Nov 3
American Airlines Logo
8:16 am - 2:10 pm
BWI
-
FLO
5h 54m
1 stop
American Airlines Logo
6:22 am - 11:09 am
FLO
-
BWI
4h 47m
1 stop
$537American Airlines
Tue, Aug 4 - Mon, Aug 10
American Airlines Logo
6:14 pm - 10:58 pm
IAD
-
FLO
4h 44m
1 stop
American Airlines Logo
5:09 am - 8:44 am
FLO
-
IAD
3h 35m
1 stop
$553American Airlines
Sat, Sep 19 - Wed, Oct 7
American Airlines Logo
8:35 am - 2:56 pm
PHL
-
FLO
6h 21m
1 stop
American Airlines Logo
5:05 am - 11:21 am
FLO
-
PHL
6h 16m
1 stop
$559American Airlines
Fri, Aug 14 - Sun, Aug 16
American Airlines Logo
5:50 pm - 11:37 pm
DCA
-
FLO
5h 47m
1 stop
American Airlines Logo
6:22 am - 12:58 pm
FLO
-
DCA
6h 36m
1 stop
$562American Airlines
Tue, Aug 4 - Mon, Aug 10
American Airlines Logo
8:16 am - 2:10 pm
BWI
-
FLO
5h 54m
1 stop
American Airlines Logo
6:22 am - 11:09 am
FLO
-
BWI
4h 47m
1 stop
$565American Airlines
Tue, Aug 4 - Mon, Aug 10
American Airlines Logo
7:57 am - 1:18 pm
IAD
-
FLO
5h 21m
1 stop
American Airlines Logo
2:34 pm - 6:45 pm
FLO
-
IAD
4h 11m
1 stop
$579American Airlines
Mon, Sep 21 - Mon, Oct 5

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American Airlines flights from Maryland to Florence, South Carolina

Our best American Airlines deals on Maryland to Florence, South Carolina flight tickets
American Airlines
Aug 4
PHL10:35 amPhiladelphia
3h 35m
1 stop
FLO2:10 pmFlorence
Aug 11
FLO6:22 amFlorence
4h 34m
1 stop
PHL10:56 amPhiladelphia
$463
American Airlines
Sep 23
IAD6:15 pmWashington, D.C. Dulles Intl
4h 43m
1 stop
FLO10:58 pmFlorence
Oct 6
FLO3:19 pmFlorence
5h 27m
1 stop
IAD8:46 pmWashington, D.C. Dulles Intl
$483
American Airlines
Nov 14
PHL1:50 pmPhiladelphia
4h 17m
1 stop
FLO6:07 pmFlorence
Nov 22
FLO11:11 amFlorence
5h 28m
1 stop
PHL4:39 pmPhiladelphia
$511

momondo Fare Finder

 
Customize your flight search to find flights from Maryland to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 6, 2026.
Use the filters below to find and compare flights from Maryland to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 8/4

10:35 am-2:10 pm

1 stop3h 35m

Florence

Tue 8/11

6:22 am-10:56 am

1 stop4h 34m

$463

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 11/14

1:50 pm-6:07 pm

1 stop4h 17m

Florence

Sun 11/22

11:11 am-4:39 pm

1 stop5h 28m

$511

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Tue 8/4

5:50 pm-11:37 pm

1 stop5h 47m

Florence

Mon 8/10

6:22 am-12:58 pm

1 stop6h 36m

$531
Quickest round-trip

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

Fri 10/30

7:15 pm-11:57 pm

1 stop4h 42m

Florence

Tue 11/3

5:15 am-8:41 am

1 stop3h 26m

$531

BaltimoreFlorence

BWI - FLO

BWIFLO

Baltimore/Washington

Tue 8/4

8:16 am-2:10 pm

1 stop5h 54m

Florence

Mon 8/10

6:22 am-11:09 am

1 stop4h 47m

$537

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

Sat 9/19

6:14 pm-10:58 pm

1 stop4h 44m

Florence

Wed 10/7

5:09 am-8:44 am

1 stop3h 35m

$553

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Fri 8/14

8:35 am-2:56 pm

1 stop6h 21m

Florence

Sun 8/16

5:05 am-11:21 am

1 stop6h 16m

$559

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Tue 8/4

5:50 pm-11:37 pm

1 stop5h 47m

Florence

Mon 8/10

6:22 am-12:58 pm

1 stop6h 36m

$562

BaltimoreFlorence

BWI - FLO

BWIFLO

Baltimore/Washington

Tue 8/4

8:16 am-2:10 pm

1 stop5h 54m

Florence

Mon 8/10

6:22 am-11:09 am

1 stop4h 47m

$565

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

Mon 9/21

7:57 am-1:18 pm

1 stop5h 21m

Florence

Mon 10/5

2:34 pm-6:45 pm

1 stop4h 11m

$579

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Maryland to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Maryland to Florence?

American Airlines is the most popular carrier operating from Maryland to Florence

What airlines fly to Florence, South Carolina?

Southwest, American Airlines and Frontier are the top three most popular airlines that fly to Florence, South Carolina from Maryland according to our data. Southwest is the first choice among our users, with 41% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 5 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Maryland to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Maryland to Florence, South Carolina

Fastest flight time

3h 15m

Direct flights

None
The fastest flight from Maryland to Florence, South Carolina takes 3h 15m
There are no direct flights from Maryland to Florence, South Carolina. There are no popular flight routes from Maryland to Florence, South Carolina.
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Frequently asked questions about flying from Maryland to Florence, South Carolina

  • When did momondo last update prices for flights from Maryland to Florence Airport?

    Prices for flights from Maryland to Florence Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Maryland to Florence Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Maryland to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Maryland to Florence?

It is quick and easy to find Maryland to Florence flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florence that suits you.

Can I find flights from Maryland to Florence with flexible booking policies on momondo?

Flights from Maryland to Florence with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Maryland to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Maryland.

I’m not ready to book a flight from Maryland to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Maryland to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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