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Cheap flights from Manchester, New Hampshire to South Carolina from $40

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to South Carolina departing on 3/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Manchester, New Hampshire to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Breeze Airways Logo
9:59 am - 12:34 pm
MHT
-
CHS
2h 35mnonstop
Breeze Airways Logo
7:00 am - 9:19 am
CHS
-
MHT
2h 19mnonstop
$98Breeze Airways
Mon, Mar 2 - Fri, Mar 6
Breeze Airways Logo
9:59 am - 12:34 pm
MHT
-
CHS
2h 35mnonstop
Breeze Airways Logo
7:00 am - 9:19 am
CHS
-
MHT
2h 19mnonstop
$102Breeze Airways
Mon, Feb 16 - Fri, Feb 20
Breeze Airways Logo
3:13 pm - 5:38 pm
MHT
-
MYR
2h 25mnonstop
Breeze Airways Logo
12:23 pm - 2:33 pm
MYR
-
MHT
2h 10mnonstop
$108Breeze Airways
Fri, Feb 6 - Mon, Feb 9
Multiple Airlines Logo
6:09 pm - 7:58 am
MHT
-
CLT
13h 49m1 stop
Multiple Airlines Logo
2:46 pm - 10:43 am
CLT
-
MHT
19h 57m2 stops
$229Multiple Airlines
Wed, Feb 25 - Wed, Mar 4
Multiple Airlines Logo
6:09 pm - 7:58 am
MHT
-
CLT
13h 49m1 stop
Multiple Airlines Logo
2:46 pm - 5:29 pm
CLT
-
MHT
26h 43m1 stop
$241Multiple Airlines
Wed, Feb 25 - Tue, Mar 3
United Airlines Logo
2:33 pm - 7:23 pm
MHT
-
SAV
4h 50m1 stop
United Airlines Logo
9:50 am - 1:58 pm
SAV
-
MHT
4h 08m1 stop
$244United Airlines
Wed, Feb 18 - Wed, Feb 25
American Airlines Logo
4:07 pm - 8:50 pm
MHT
-
SAV
4h 43m1 stop
American Airlines Logo
6:25 am - 3:42 pm
SAV
-
MHT
9h 17m2 stops
$264American Airlines
Wed, Feb 18 - Wed, Feb 25
United Airlines Logo
2:17 pm - 7:25 pm
MHT
-
SAV
5h 08m1 stop
United Airlines Logo
2:13 pm - 6:51 pm
SAV
-
MHT
4h 38m1 stop
$265United Airlines
Tue, Jan 27 - Sat, Jan 31
American Airlines Logo
5:30 am - 10:54 am
MHT
-
CAE
5h 24m1 stop
American Airlines Logo
6:10 pm - 11:46 pm
CAE
-
MHT
5h 36m1 stop
$269American Airlines
Mon, Jan 19 - Wed, Feb 11
Southwest Logo
5:00 am - 6:00 pm
MHT
-
GSP
13h 00m2 stops
Southwest Logo
11:15 am - 10:05 pm
GSP
-
MHT
10h 50m2 stops
$339Southwest
Sun, Jan 25 - Wed, Jan 28

Southwest flights from Manchester, New Hampshire to South Carolina

Our best Southwest deals on Manchester, New Hampshire to South Carolina flight tickets
Southwest
Feb 20
MHT5:00 amManchester
10h 00m
2 stops
CHS3:00 pmCharleston
Feb 24
CHS7:55 amCharleston
6h 55m
1 stop
MHT2:50 pmManchester
$299
Find similar
Southwest
Jan 13
MHT5:55 amManchester
4h 25m
1 stop
CLT10:20 amCharlotte Douglas
Jan 17
CLT5:25 pmCharlotte Douglas
4h 40m
1 stop
MHT10:05 pmManchester
$323
Find similar
Southwest
Jan 13
MHT5:55 amManchester
4h 25m
1 stop
CLT10:20 amCharlotte Douglas
Jan 17
CLT1:05 pmCharlotte Douglas
9h 00m
2 stops
MHT10:05 pmManchester
$328
Find similar

United Airlines flights from Manchester, New Hampshire to South Carolina

Our best United Airlines deals on Manchester, New Hampshire to South Carolina flight tickets
United Airlines
Feb 18
MHT2:33 pmManchester
4h 50m
1 stop
SAV7:23 pmSavannah/Hilton Head
Feb 25
SAV9:50 amSavannah/Hilton Head
4h 08m
1 stop
MHT1:58 pmManchester
$244
Find similar
United Airlines
Feb 2
MHT2:17 pmManchester
4h 47m
1 stop
CHS7:04 pmCharleston
Feb 5
CHS2:58 pmCharleston
3h 53m
1 stop
MHT6:51 pmManchester
$247
Find similar
United Airlines
Feb 2
MHT2:17 pmManchester
9h 27m
2 stops
CHS11:44 pmCharleston
Feb 5
CHS2:58 pmCharleston
3h 53m
1 stop
MHT6:51 pmManchester
$252
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterCharleston

MHT - CHS

MHTCHS

Manchester

Mon 3/2

9:59 am-12:34 pm

Nonstop2h 35m

Charleston

Fri 3/6

7:00 am-9:19 am

Nonstop2h 19m

$98

ManchesterCharleston

MHT - CHS

MHTCHS

Manchester

Mon 2/16

9:59 am-12:34 pm

Nonstop2h 35m

Charleston

Fri 2/20

7:00 am-9:19 am

Nonstop2h 19m

$102

ManchesterMyrtle Beach

MHT - MYR

MHTMYR

Manchester

Fri 2/6

3:13 pm-5:38 pm

Nonstop2h 25m

Myrtle Beach Intl

Mon 2/9

12:23 pm-2:33 pm

Nonstop2h 10m

$108

ManchesterCharlotte

MHT - CLT

MHTCLT

Manchester

Wed 2/25

6:09 pm-7:58 am

1 stop13h 49m

Charlotte Douglas

Wed 3/4

2:46 pm-10:43 am

2 stops19h 57m

$229

ManchesterCharlotte

MHT - CLT

MHTCLT

Manchester

Wed 2/25

6:09 pm-7:58 am

1 stop13h 49m

Charlotte Douglas

Tue 3/3

2:46 pm-5:29 pm

1 stop26h 43m

$241

ManchesterSavannah

MHT - SAV

MHTSAV

Manchester

Wed 2/18

2:33 pm-7:23 pm

1 stop4h 50m

Savannah/Hilton Head

Wed 2/25

9:50 am-1:58 pm

1 stop4h 08m

$244

ManchesterSavannah

MHT - SAV

MHTSAV

Manchester

Wed 2/18

4:07 pm-8:50 pm

1 stop4h 43m

Savannah/Hilton Head

Wed 2/25

6:25 am-3:42 pm

2 stops9h 17m

$264

ManchesterSavannah

MHT - SAV

MHTSAV

Manchester

Tue 1/27

2:17 pm-7:25 pm

1 stop5h 08m

Savannah/Hilton Head

Sat 1/31

2:13 pm-6:51 pm

1 stop4h 38m

$265

ManchesterColumbia

MHT - CAE

MHTCAE

Manchester

Mon 1/19

5:30 am-10:54 am

1 stop5h 24m

Columbia Metropolitan

Wed 2/11

6:10 pm-11:46 pm

1 stop5h 36m

$269

ManchesterGreenville

MHT - GSP

MHTGSP

Manchester

Sun 1/25

5:00 am-6:00 pm

2 stops13h 00m

Greenville

Wed 1/28

11:15 am-10:05 pm

2 stops10h 50m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Manchester, New Hampshire to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Manchester, New Hampshire is in September. Flight prices, which tend to average around $101, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Manchester, New Hampshire during January instead. Flights to South Carolina in January, while not as cheap as those in September, still average around $126.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Monday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $131. The most expensive day to fly to South Carolina is Saturday, with ticket prices averaging around $231.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Manchester, New Hampshire to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $140. Try not to purchase tickets in the evening because they tend to be around $309. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Manchester to South Carolina flight route?

Fly from Manchester to Myrtle Beach Intl for the best Manchester - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Manchester, New Hampshire when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $185 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Manchester, New Hampshire for as low as $154 on momondo.

What cabin class options are available on Manchester to South Carolina flights?

There are 2 cabin classes available to choose from on Manchester to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Manchester, New Hampshire to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Manchester, New Hampshire to South Carolina.

Cheap Manchester, New Hampshire to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to South Carolina

Best Price Found

$49

Fastest flight time

2h 25m

Direct flights

Mon, Tue, Wed, Thu, Sat and Sun

Airports in South Carolina

57 airports
The best one-way flight to South Carolina from Manchester, New Hampshire in the past 72 hours is $49. The best round-trip flight deal from Manchester, New Hampshire to South Carolina found on momondo in the last 72 hours is $138.
The fastest flight from Manchester, New Hampshire to South Carolina takes 2h 25m
Direct flights go from Manchester, New Hampshire to South Carolina on Monday, Tuesday, Wednesday, Thursday, Saturday and Sunday. The only airline offering direct flights is Breeze Airways.
There are 57 airports in South Carolina. From Manchester, New Hampshire there are direct flights to Myrtle Beach Intl (MYR), Charlotte Douglas (CLT), Charleston (CHS).
Search flight deals

  • When did momondo last update prices for flights from Manchester Airport to South Carolina?

    Prices for flights from Manchester Airport to South Carolina were last updated today.

  • How many operators does momondo search for flights from Manchester Airport to South Carolina?

  • How old do you have to be to fly from Manchester Airport to South Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Manchester, New Hampshire to South Carolina?

Best airlines flying from Manchester, New Hampshire to South Carolina

Compare and see reviews for airlines that fly from Manchester, New Hampshire to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
Avelo AirlinesPriceFrom $58Free CancellationRating
7.5
85 reviews
Search Avelo Airlines flights
JetBluePriceFrom $63Free CancellationRating
7.2
2,895 reviews
Search JetBlue flights
Spirit AirlinesPriceFrom $80Free CancellationRating
6.3
8,190 reviews
Search Spirit Airlines flights
Breeze AirwaysPriceFrom $85Free CancellationRating
8.2
249 reviews
Search Breeze Airways flights
United AirlinesPriceFrom $168Free CancellationRating
7.4
9,100 reviews
Search United Airlines flights
American AirlinesPriceFrom $217Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights
SouthwestPriceFrom $220Free CancellationRating
8.0
4,254 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to South Carolina for you.

Can I find flights from Manchester to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Manchester to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Manchester to South Carolina?

Once all potential Manchester to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Manchester to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

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