What is the cheapest airline that flies from Manchester to South Carolina?

Southwest, Breeze Airways, and United Airlines are the most popular carriers operating from Manchester to South Carolina

How many flights depart from Manchester, New Hampshire to South Carolina on average per week?

The number of flights available between Manchester, New Hampshire and South Carolina is 2 per week as of September 2026. The most frequent departure day is Mon, with 50% of weekly flights leaving on this day.

What airlines fly to South Carolina?

JetBlue, American Airlines and Breeze Airways are the top three most popular airlines that fly to South Carolina from Manchester, New Hampshire according to our data. JetBlue is the first choice among our users, with 28% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 7 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Manchester Airport to South Carolina?

Prices for flights from Manchester Airport to South Carolina were last updated today.

How many operators does momondo search for flights from Manchester Airport to South Carolina?

The number of operators available for flights from Manchester Airport to South Carolina is 5 as of September 2026.

How old do you have to be to fly from Manchester Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$51 Cheap Flights from Manchester, New Hampshire to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Manchester, New Hampshire to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

12:18 pm - 3:02 pmMHT Manchester-CHS Charleston

2h 44mnonstop

9:18 am - 11:38 amCHS Charleston-MHT Manchester

2h 20mnonstop

$101Breeze Airways

Sat, Dec 12 - Wed, Dec 16

12:18 pm - 3:02 pmMHT Manchester-CHS Charleston

2h 44mnonstop

9:18 am - 11:38 amCHS Charleston-MHT Manchester

2h 20mnonstop

$103Breeze Airways

Sat, Dec 12 - Wed, Dec 16

12:18 pm - 3:02 pmMHT Manchester-CHS Charleston

2h 44mnonstop

3:42 pm - 11:44 amCHS Charleston-MHT Manchester

20h 02m2 stops Orlando Raleigh-Durham

$296Multiple Airlines

Sat, Nov 14 - Wed, Nov 18

12:18 pm - 3:02 pmMHT Manchester-CHS Charleston

2h 44mnonstop

3:42 pm - 11:44 amCHS Charleston-MHT Manchester

20h 02m2 stops Orlando Raleigh-Durham

$307Multiple Airlines

Wed, Nov 11 - Wed, Nov 18

7:15 pm - 11:47 pmMHT Manchester-MYR Myrtle Beach Intl

4h 32m1 stop Charlotte Douglas

4:03 pm - 9:44 pmMYR Myrtle Beach Intl-MHT Manchester

5h 41m1 stop Washington, D.C. Reagan-National

$325American Airlines

Wed, Oct 21 - Sat, Oct 24

7:15 pm - 11:47 pmMHT Manchester-MYR Myrtle Beach Intl

4h 32m1 stop Charlotte Douglas

5:00 am - 9:34 amMYR Myrtle Beach Intl-MHT Manchester

4h 34m1 stop Charlotte Douglas

$325American Airlines

Mon, Oct 19 - Mon, Oct 26

5:25 am - 9:45 amMHT Manchester-MYR Myrtle Beach Intl

4h 20m1 stop Baltimore/Washington

6:15 am - 12:00 pmMYR Myrtle Beach Intl-MHT Manchester

5h 45m1 stop Baltimore/Washington

$325Southwest

Mon, Oct 26 - Thu, Oct 29

1:00 pm - 7:30 pmMHT Manchester-GSP Greenville

6h 30m1 stop Baltimore/Washington

2:50 pm - 6:45 pmGSP Greenville-MHT Manchester

3h 55m1 stop Baltimore/Washington

$325Southwest

Sat, Dec 12 - Mon, Dec 14

9:25 am - 8:58 pmMHT Manchester-GSP Greenville

11h 33m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

7:43 pm - 11:59 pmGSP Greenville-MHT Manchester

4h 16m1 stop Washington, D.C. Dulles Intl

$330United Airlines

Sat, Oct 31 - Sat, Nov 7

9:25 am - 5:11 pmMHT Manchester-MYR Myrtle Beach Intl

7h 46m2 stops Washington, D.C. Dulles Intl Newark

11:27 am - 11:59 pmMYR Myrtle Beach Intl-MHT Manchester

12h 32m2 stops Newark Washington, D.C. Reagan-National

$335United Airlines

Sat, Nov 14 - Tue, Nov 17

Cheap last minute flights

Enter your travel dates to find the best prices.

12:18 pm - 3:02 pmMHT Manchester-CHS Charleston

2h 44mnonstop

9:18 am - 11:38 amCHS Charleston-MHT Manchester

2h 20mnonstop

$206Breeze Airways

Sat, Oct 3 - Sat, Oct 17

12:18 pm - 3:02 pmMHT Manchester-CHS Charleston

2h 44mnonstop

9:18 am - 11:38 amCHS Charleston-MHT Manchester

2h 20mnonstop

$237Breeze Airways

Sat, Oct 3 - Sat, Oct 10

5:35 am - 12:35 pmMHT Manchester-CHS Charleston

7h 00m1 stop Baltimore/Washington

8:05 pm - 11:55 pmCHS Charleston-MHT Manchester

3h 50m1 stop Baltimore/Washington

$467Southwest

Wed, Sep 30 - Thu, Oct 1

9:25 am - 3:00 pmMHT Manchester-CHS Charleston

5h 35m1 stop Washington, D.C. Dulles Intl

3:00 pm - 7:01 pmCHS Charleston-MHT Manchester

4h 01m1 stop Washington, D.C. Dulles Intl

$467United Airlines

Wed, Sep 30 - Sat, Oct 3

5:35 am - 12:35 pmMHT Manchester-CHS Charleston

7h 00m1 stop Baltimore/Washington

6:15 am - 4:05 pmCHS Charleston-MHT Manchester

9h 50m2 stops Nashville Intl Baltimore/Washington

$472Southwest

Wed, Sep 30 - Sat, Oct 3

9:25 am - 3:10 pmMHT Manchester-CHS Charleston

5h 45m1 stop Washington, D.C. Dulles Intl

8:00 am - 7:01 pmCHS Charleston-MHT Manchester

11h 01m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$472United Airlines

Sat, Oct 3 - Sat, Oct 10

12:18 pm - 3:02 pmMHT Manchester-CHS Charleston

2h 44mnonstop

3:00 pm - 11:44 amCHS Charleston-MHT Manchester

44h 44m2 stops Orlando Raleigh-Durham

$514Multiple Airlines

Wed, Sep 30 - Tue, Oct 13

12:18 pm - 1:57 pmMHT Manchester-MYR Myrtle Beach Intl

25h 39m3 stops Charleston Orlando Akron/Canton

12:24 pm - 2:34 pmMYR Myrtle Beach Intl-MHT Manchester

2h 10mnonstop

$537Multiple Airlines

Sat, Oct 3 - Fri, Nov 6

4:44 pm - 11:05 pmMHT Manchester-CHS Charleston

6h 21m1 stop Charlotte Douglas

4:34 pm - 10:56 pmCHS Charleston-MHT Manchester

6h 22m1 stop Charlotte Douglas

$569American Airlines

Sat, Oct 3 - Wed, Oct 7

7:05 am - 1:26 pmMHT Manchester-MYR Myrtle Beach Intl

6h 21m1 stop Charlotte Douglas

4:03 pm - 9:44 pmMYR Myrtle Beach Intl-MHT Manchester

5h 41m1 stop Washington, D.C. Reagan-National

$585American Airlines

Sat, Oct 3 - Sat, Oct 10

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Breeze Airways flights from Manchester, New Hampshire to South Carolina

Our best Breeze Airways deals on Manchester, New Hampshire to South Carolina flight tickets

Breeze Airways

Dec 12

MHT12:18 pmManchester

2h 44m

CHS3:02 pmCharleston

Dec 16

CHS9:18 amCharleston

2h 20m

MHT11:38 amManchester

$101

Breeze Airways

Dec 12

MHT12:18 pmManchester

2h 44m

CHS3:02 pmCharleston

Dec 16

CHS9:18 amCharleston

2h 20m

MHT11:38 amManchester

$103

Breeze Airways

Jan 9

MHT12:18 pmManchester

2h 44m

CHS3:02 pmCharleston

Jan 16

CHS9:18 amCharleston

2h 20m

MHT11:38 amManchester

$117

Southwest flights from Manchester, New Hampshire to South Carolina

Our best Southwest deals on Manchester, New Hampshire to South Carolina flight tickets

Southwest

Dec 12

MHT1:00 pmManchester

6h 30m

1 stop

GSP7:30 pmGreenville

Dec 14

GSP2:50 pmGreenville

3h 55m

1 stop

MHT6:45 pmManchester

$325

Southwest

Oct 26

MHT5:25 amManchester

4h 20m

1 stop

MYR9:45 amMyrtle Beach Intl

Oct 29

MYR10:25 amMyrtle Beach Intl

11h 30m

2 stops

MHT9:55 pmManchester

$330

Southwest

Dec 12

MHT7:45 amManchester

11h 45m

2 stops

GSP7:30 pmGreenville

Dec 14

GSP2:50 pmGreenville

3h 55m

1 stop

MHT6:45 pmManchester

$336

momondo Fare Finder

Use the filters below to find and compare flights from Manchester, New Hampshire to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

ManchesterCharleston

MHT Manchester - CHS Charleston

MHTCHS

Manchester

Sat 12/12

12:18 pm-3:02 pm

Nonstop2h 44m

Charleston

Wed 12/16

9:18 am-11:38 am

Nonstop2h 20m

$101

ManchesterCharleston

MHT Manchester - CHS Charleston

MHTCHS

Manchester

Sat 12/12

12:18 pm-3:02 pm

Nonstop2h 44m

Charleston

Wed 12/16

9:18 am-11:38 am

Nonstop2h 20m

$103

ManchesterCharleston

MHT Manchester - CHS Charleston

MHTCHS

Manchester

Sat 11/14

12:18 pm-3:02 pm

Nonstop2h 44m

Charleston

Wed 11/18

3:42 pm-11:44 am

2 stops20h 02m

$296

ManchesterCharleston

MHT Manchester - CHS Charleston

MHTCHS

Manchester

Wed 11/11

12:18 pm-3:02 pm

Nonstop2h 44m

Charleston

Wed 11/18

3:42 pm-11:44 am

2 stops20h 02m

$307

ManchesterMyrtle Beach

MHT Manchester - MYR Myrtle Beach Intl

MHTMYR

Manchester

Wed 10/21

7:15 pm-11:47 pm

1 stop4h 32m

Myrtle Beach Intl

Sat 10/24

4:03 pm-9:44 pm

1 stop5h 41m

$325

ManchesterMyrtle Beach

MHT Manchester - MYR Myrtle Beach Intl

MHTMYR

Manchester

Mon 10/19

7:15 pm-11:47 pm

1 stop4h 32m

Myrtle Beach Intl

Mon 10/26

5:00 am-9:34 am

1 stop4h 34m

$325

ManchesterMyrtle Beach

MHT Manchester - MYR Myrtle Beach Intl

MHTMYR

Manchester

Mon 10/26

5:25 am-9:45 am

1 stop4h 20m

Myrtle Beach Intl

Thu 10/29

6:15 am-12:00 pm

1 stop5h 45m

$325

ManchesterGreenville

MHT Manchester - GSP Greenville

MHTGSP

Manchester

Sat 12/12

1:00 pm-7:30 pm

1 stop6h 30m

Greenville

Mon 12/14

2:50 pm-6:45 pm

1 stop3h 55m

$325

ManchesterGreenville

MHT Manchester - GSP Greenville

MHTGSP

Manchester

Sat 10/31

9:25 am-8:58 pm

2 stops11h 33m

Greenville

Sat 11/7

7:43 pm-11:59 pm

1 stop4h 16m

$330

ManchesterMyrtle Beach

MHT Manchester - MYR Myrtle Beach Intl

MHTMYR

Manchester

Sat 11/14

9:25 am-5:11 pm

2 stops7h 46m

Myrtle Beach Intl

Tue 11/17

11:27 am-11:59 pm

2 stops12h 32m

$335

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Manchester, New Hampshire to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Manchester, New Hampshire is in February. Flight prices, which tend to average around $243, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to South Carolina from Manchester, New Hampshire during March instead. Flights to South Carolina in March, while not as cheap as those in February, still average around $264.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $160. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $233.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Manchester, New Hampshire to South Carolina flights are usually those with departure times at noon. Our users have found flights to South Carolina at noon for as low as $182. Try not to purchase tickets in the morning because they tend to be around $212. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Manchester to South Carolina flight route?

Fly from Manchester to Charleston for the best Manchester - South Carolina flight prices

How far in advance should I book a flight from Manchester, New Hampshire to South Carolina?

You are more likely to see cheaper flights to South Carolina from Manchester, New Hampshire when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $247 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Manchester, New Hampshire for as low as $176 on momondo.

What cabin class options are available on Manchester, New Hampshire to South Carolina flights?

There are 2 cabin classes available to choose from on Manchester, New Hampshire to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Manchester, New Hampshire to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Manchester, New Hampshire to South Carolina.

Cheap Manchester, New Hampshire to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to South Carolina

Best Price Found	$51
Fastest flight time	2h 18m
Direct flights	Tue, Thu, Sat and Sun
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Manchester, New Hampshire in the past 72 hours is $51. The best round-trip flight deal from Manchester, New Hampshire to South Carolina found on momondo in the last 72 hours is $101.

The fastest flight from Manchester, New Hampshire to South Carolina takes 2h 18m

Direct flights go from Manchester, New Hampshire to South Carolina on Tuesday, Thursday, Saturday and Sunday. The only airline offering direct flights is Breeze Airways.

There are 57 airports in South Carolina. From Manchester, New Hampshire there are direct flights to Myrtle Beach Intl (MYR), Charleston (CHS).

Search flight deals

Frequently asked questions about flying from Manchester, New Hampshire to South Carolina

When did momondo last update prices for flights from Manchester Airport to South Carolina?
Prices for flights from Manchester Airport to South Carolina were last updated today.
How many operators does momondo search for flights from Manchester Airport to South Carolina?
The number of operators available for flights from Manchester Airport to South Carolina is 5 as of September 2026.
How old do you have to be to fly from Manchester Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents you'll need for your trip to South Carolina may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South Carolina. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Manchester, New Hampshire to South Carolina?
Based on momondo bookings for flights between Manchester, New Hampshire and South Carolina, the leading plane model is Airbus A220-300, making up 61.28% of the total bookings. Other popular models include Boeing 737-800 Passenger/BBJ2 (winglets) with 9.33%, Airbus A320-100/200 with 7.94%, and Boeing 737 MAX 8 with 6.69%.

Best airlines flying from Manchester, New Hampshire to South Carolina

Compare and see reviews for airlines that fly from Manchester, New Hampshire to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Avelo Airlines	PriceFrom $58	Free Cancellation	Rating 7.5 85 reviews	Search Avelo Airlines flights
Breeze Airways	PriceFrom $98	Free Cancellation	Rating 8.2 323 reviews	Search Breeze Airways flights
United Airlines	PriceFrom $193	Free Cancellation	Rating 7.4 10,250 reviews	Search United Airlines flights
American Airlines	PriceFrom $246	Free Cancellation	Rating 7.0 12,098 reviews	Search American Airlines flights
Southwest	PriceFrom $286	Free Cancellation	Rating 8.0 4,201 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Manchester to South Carolina for you.

Can I find flights from Manchester to South Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Manchester to South Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Manchester to South Carolina?

Once all potential Manchester to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Manchester to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.