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Cheap flights from Manchester, New Hampshire to Knoxville from $165

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Knoxville departing on 8/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Manchester, New Hampshire to Knoxville

Cheap round-trip flights

United Airlines Logo
1:30 pm - 8:56 pmMHT-TYS
7h 26m1 stop
United Airlines Logo
5:45 am - 10:42 amTYS-MHT
4h 57m1 stop
$249United Airlines
Find Deal
Sat, Aug 30 - Thu, Sep 4
American Airlines Logo
10:30 am - 5:47 pmMHT-TYS
7h 17m1 stop
American Airlines Logo
6:13 am - 12:14 pmTYS-MHT
6h 01m1 stop
$254American Airlines
Find Deal
Wed, Aug 20 - Tue, Aug 26
American Airlines Logo
3:56 pm - 8:55 pmMHT-TYS
4h 59m1 stop
American Airlines Logo
7:55 am - 4:57 pmTYS-MHT
9h 02m2 stops
$259American Airlines
Find Deal
Wed, Aug 20 - Tue, Aug 26
American Airlines Logo
12:45 pm - 6:54 pmMHT-TYS
6h 09m2 stops
American Airlines Logo
12:03 pm - 9:13 pmTYS-MHT
9h 10m2 stops
$264American Airlines
Find Deal
Wed, Aug 20 - Tue, Aug 26
American Airlines Logo
6:00 am - 10:37 amMHT-TYS
4h 37m1 stop
American Airlines Logo
6:25 am - 11:38 amTYS-MHT
5h 13m1 stop
$301American Airlines
Find Deal
Tue, Sep 23 - Sat, Sep 27
American Airlines Logo
5:26 pm - 9:41 pmMHT-TYS
4h 15m1 stop
American Airlines Logo
8:23 am - 5:28 pmTYS-MHT
9h 05m2 stops
$306American Airlines
Find Deal
Tue, Sep 23 - Sat, Sep 27
American Airlines Logo
3:22 pm - 8:50 pmMHT-TYS
5h 28m1 stop
American Airlines Logo
3:56 pm - 10:24 pmTYS-MHT
6h 28m1 stop
$319American Airlines
Find Deal
Sat, Sep 27 - Wed, Oct 1
American Airlines Logo
3:56 pm - 8:55 pmMHT-TYS
4h 59m1 stop
American Airlines Logo
6:13 am - 4:57 pmTYS-MHT
10h 44m1 stop
$321American Airlines
Find Deal
Thu, Aug 28 - Mon, Sep 1
United Airlines Logo
9:40 am - 2:40 pmMHT-TYS
5h 00m1 stop
United Airlines Logo
5:45 am - 10:42 amTYS-MHT
4h 57m1 stop
$324United Airlines
Find Deal
Sat, Aug 23 - Sun, Aug 31
United Airlines Logo
9:40 am - 2:40 pmMHT-TYS
5h 00m1 stop
United Airlines Logo
7:00 am - 2:57 pmTYS-MHT
7h 57m2 stops
$329United Airlines
Find Deal
Sat, Aug 23 - Wed, Aug 27

United Airlines flights from Manchester, New Hampshire to Knoxville

Our best United Airlines deals on Manchester, New Hampshire to Knoxville flight tickets
United Airlines
Aug 30
MHT1:30 pmManchester
7h 26m
1 stop
TYS8:56 pmKnoxville McGhee Tyson
Sep 4
TYS5:45 amKnoxville McGhee Tyson
4h 57m
1 stop
MHT10:42 amManchester
$249
Find similar
United Airlines
Aug 23
MHT9:40 amManchester
5h 00m
1 stop
TYS2:40 pmKnoxville McGhee Tyson
Aug 31
TYS5:45 amKnoxville McGhee Tyson
4h 57m
1 stop
MHT10:42 amManchester
$324
Find similar
United Airlines
Aug 23
MHT9:40 amManchester
5h 00m
1 stop
TYS2:40 pmKnoxville McGhee Tyson
Aug 27
TYS7:00 amKnoxville McGhee Tyson
7h 57m
2 stops
MHT2:57 pmManchester
$329
Find similar

American Airlines flights from Manchester, New Hampshire to Knoxville

Our best American Airlines deals on Manchester, New Hampshire to Knoxville flight tickets
American Airlines
Aug 20
MHT10:30 amManchester
7h 17m
1 stop
TYS5:47 pmKnoxville McGhee Tyson
Aug 26
TYS6:13 amKnoxville McGhee Tyson
6h 01m
1 stop
MHT12:14 pmManchester
$254
Find similar
American Airlines
Aug 20
MHT3:56 pmManchester
4h 59m
1 stop
TYS8:55 pmKnoxville McGhee Tyson
Aug 26
TYS7:55 amKnoxville McGhee Tyson
9h 02m
2 stops
MHT4:57 pmManchester
$259
Find similar
American Airlines
Aug 20
MHT12:45 pmManchester
6h 09m
2 stops
TYS6:54 pmKnoxville McGhee Tyson
Aug 26
TYS12:03 pmKnoxville McGhee Tyson
9h 10m
2 stops
MHT9:13 pmManchester
$264
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sat 8/30

1:30 pm-8:56 pm

1 stop7h 26m

Knoxville McGhee Tyson

Thu 9/4

5:45 am-10:42 am

1 stop4h 57m

$249

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 8/20

10:30 am-5:47 pm

1 stop7h 17m

Knoxville McGhee Tyson

Tue 8/26

6:13 am-12:14 pm

1 stop6h 01m

$254

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 8/20

3:56 pm-8:55 pm

1 stop4h 59m

Knoxville McGhee Tyson

Tue 8/26

7:55 am-4:57 pm

2 stops9h 02m

$259

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 8/20

12:45 pm-6:54 pm

2 stops6h 09m

Knoxville McGhee Tyson

Tue 8/26

12:03 pm-9:13 pm

2 stops9h 10m

$264

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 9/23

6:00 am-10:37 am

1 stop4h 37m

Knoxville McGhee Tyson

Sat 9/27

6:25 am-11:38 am

1 stop5h 13m

$301

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 9/23

5:26 pm-9:41 pm

1 stop4h 15m

Knoxville McGhee Tyson

Sat 9/27

8:23 am-5:28 pm

2 stops9h 05m

$306

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sat 9/27

3:22 pm-8:50 pm

1 stop5h 28m

Knoxville McGhee Tyson

Wed 10/1

3:56 pm-10:24 pm

1 stop6h 28m

$319

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 8/28

3:56 pm-8:55 pm

1 stop4h 59m

Knoxville McGhee Tyson

Mon 9/1

6:13 am-4:57 pm

1 stop10h 44m

$321

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sat 8/23

9:40 am-2:40 pm

1 stop5h 00m

Knoxville McGhee Tyson

Sun 8/31

5:45 am-10:42 am

1 stop4h 57m

$324

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sat 8/23

9:40 am-2:40 pm

1 stop5h 00m

Knoxville McGhee Tyson

Wed 8/27

7:00 am-2:57 pm

2 stops7h 57m

$329

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Manchester, New Hampshire to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Manchester, New Hampshire and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Manchester, New Hampshire, with most prices found around $370. If you aren’t able to travel during the month of August, then book flights to Knoxville from Manchester, New Hampshire during June instead. Flights to Knoxville in June, while not as cheap as those in August, still average around $379.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Manchester, New Hampshire to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $111. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Manchester, New Hampshire to Knoxville for around $251.

What is the cheapest time of day to depart on your flight to Knoxville?

In the morning is the cheapest time of day to fly from Manchester, New Hampshire to Knoxville when you can find flight prices for as low as $189. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $604.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Manchester, New Hampshire when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $526 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Manchester, New Hampshire for as low as $282 on momondo.

When to book flights from Manchester, New Hampshire to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Knoxville (MHT to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Knoxville

Best Price Found

$165

Fastest flight time

4h 05m

Direct flights

None

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Manchester, New Hampshire in the past 72 hours is $165. The best round-trip flight deal from Manchester, New Hampshire to Knoxville found on momondo in the last 72 hours is $249.
The fastest flight from Manchester, New Hampshire to Knoxville takes 4h 05m
There are no direct flights from Manchester, New Hampshire to Knoxville. Popular non-direct route for this connection is Manchester Airport - Knoxville McGhee Tyson Airport.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Manchester to Knoxville McGhee Tyson by plane?

    A flight from Manchester to Knoxville McGhee Tyson will travel around 821.5 mi. In terms of flight time, this usually takes a little over 4h 05m.

  • When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester, New Hampshire to Knoxville?

Best airlines flying from Manchester, New Hampshire to Knoxville

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $248Free CancellationRating
7.4
8,917 reviews
Search United Airlines flights
American AirlinesPriceFrom $300Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Newport
Alcoa
Lenoir City
Oak Ridge
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Manchester.

Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Knoxville.

I’m not ready to book a flight from Manchester to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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