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Cheap flights from Manchester, New Hampshire to Knoxville from $181

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Knoxville departing on 10/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Manchester, New Hampshire to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:41 am - 10:50 amMHT-TYS
5h 09m1 stop
American Airlines Logo
6:00 am - 11:47 amTYS-MHT
5h 47m1 stop
$231American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
5:16 pm - 9:36 pmMHT-TYS
4h 20m1 stop
American Airlines Logo
1:37 pm - 10:19 pmTYS-MHT
8h 42m2 stops
$236American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
3:42 pm - 8:48 pmMHT-TYS
5h 06m1 stop
American Airlines Logo
4:22 pm - 11:34 pmTYS-MHT
7h 12m1 stop
$261American Airlines
Find Deal
Mon, Dec 15 - Thu, Dec 18
American Airlines Logo
5:41 am - 2:27 pmMHT-TYS
8h 46m2 stops
American Airlines Logo
4:22 pm - 11:34 pmTYS-MHT
7h 12m1 stop
$266American Airlines
Find Deal
Mon, Dec 15 - Thu, Dec 18
American Airlines Logo
5:41 am - 3:14 pmMHT-TYS
9h 33m2 stops
American Airlines Logo
4:12 pm - 11:34 pmTYS-MHT
7h 22m2 stops
$271American Airlines
Find Deal
Mon, Dec 15 - Thu, Dec 18
Southwest Logo
9:15 am - 6:10 pmMHT-TYS
8h 55m2 stops
Southwest Logo
8:05 am - 12:35 pmTYS-MHT
4h 30m1 stop
$362Southwest
Find Deal
Thu, Apr 16 - Mon, Apr 20
Southwest Logo
9:15 am - 6:10 pmMHT-TYS
8h 55m2 stops
Southwest Logo
8:05 am - 4:00 pmTYS-MHT
7h 55m2 stops
$367Southwest
Find Deal
Thu, Apr 16 - Mon, Apr 20
United Airlines Logo
9:30 am - 2:43 pmMHT-TYS
5h 13m1 stop
United Airlines Logo
7:20 pm - 11:44 pmTYS-MHT
4h 24m1 stop
$477United Airlines
Find Deal
Tue, Nov 4 - Tue, Nov 11
United Airlines Logo
9:30 am - 2:43 pmMHT-TYS
5h 13m1 stop
United Airlines Logo
1:52 pm - 11:44 pmTYS-MHT
9h 52m2 stops
$482United Airlines
Find Deal
Tue, Nov 4 - Sat, Nov 8
United Airlines Logo
9:30 am - 10:48 amMHT-TYS
25h 18m1 stop
United Airlines Logo
9:50 am - 1:47 pmTYS-MHT
3h 57m1 stop
$487United Airlines
Find Deal
Fri, Nov 7 - Mon, Nov 10

American Airlines flights from Manchester, New Hampshire to Knoxville

Our best American Airlines deals on Manchester, New Hampshire to Knoxville flight tickets
American Airlines
Dec 10
MHT5:41 amManchester
5h 09m
1 stop
TYS10:50 amKnoxville McGhee Tyson
Dec 13
TYS6:00 amKnoxville McGhee Tyson
5h 47m
1 stop
MHT11:47 amManchester
$231
Find similar
American Airlines
Dec 10
MHT5:16 pmManchester
4h 20m
1 stop
TYS9:36 pmKnoxville McGhee Tyson
Dec 13
TYS1:37 pmKnoxville McGhee Tyson
8h 42m
2 stops
MHT10:19 pmManchester
$236
Find similar
American Airlines
Dec 15
MHT3:42 pmManchester
5h 06m
1 stop
TYS8:48 pmKnoxville McGhee Tyson
Dec 18
TYS4:22 pmKnoxville McGhee Tyson
7h 12m
1 stop
MHT11:34 pmManchester
$261
Find similar

United Airlines flights from Manchester, New Hampshire to Knoxville

Our best United Airlines deals on Manchester, New Hampshire to Knoxville flight tickets
United Airlines
Nov 4
MHT9:30 amManchester
5h 13m
1 stop
TYS2:43 pmKnoxville McGhee Tyson
Nov 11
TYS7:20 pmKnoxville McGhee Tyson
4h 24m
1 stop
MHT11:44 pmManchester
$477
Find similar
United Airlines
Nov 4
MHT9:30 amManchester
5h 13m
1 stop
TYS2:43 pmKnoxville McGhee Tyson
Nov 8
TYS1:52 pmKnoxville McGhee Tyson
9h 52m
2 stops
MHT11:44 pmManchester
$482
Find similar
United Airlines
Nov 7
MHT9:30 amManchester
25h 18m
1 stop
TYS10:48 amKnoxville McGhee Tyson
Nov 10
TYS9:50 amKnoxville McGhee Tyson
3h 57m
1 stop
MHT1:47 pmManchester
$487
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Manchester, New Hampshire to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 12/10

5:41 am-10:50 am

1 stop5h 09m

Knoxville McGhee Tyson

Sat 12/13

6:00 am-11:47 am

1 stop5h 47m

$231

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 12/10

5:16 pm-9:36 pm

1 stop4h 20m

Knoxville McGhee Tyson

Sat 12/13

1:37 pm-10:19 pm

2 stops8h 42m

$236

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Mon 12/15

3:42 pm-8:48 pm

1 stop5h 06m

Knoxville McGhee Tyson

Thu 12/18

4:22 pm-11:34 pm

1 stop7h 12m

$261

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Mon 12/15

5:41 am-2:27 pm

2 stops8h 46m

Knoxville McGhee Tyson

Thu 12/18

4:22 pm-11:34 pm

1 stop7h 12m

$266

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Mon 12/15

5:41 am-3:14 pm

2 stops9h 33m

Knoxville McGhee Tyson

Thu 12/18

4:12 pm-11:34 pm

2 stops7h 22m

$271

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 4/16

9:15 am-6:10 pm

2 stops8h 55m

Knoxville McGhee Tyson

Mon 4/20

8:05 am-12:35 pm

1 stop4h 30m

$362

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 4/16

9:15 am-6:10 pm

2 stops8h 55m

Knoxville McGhee Tyson

Mon 4/20

8:05 am-4:00 pm

2 stops7h 55m

$367

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 11/4

9:30 am-2:43 pm

1 stop5h 13m

Knoxville McGhee Tyson

Tue 11/11

7:20 pm-11:44 pm

1 stop4h 24m

$477

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Tue 11/4

9:30 am-2:43 pm

1 stop5h 13m

Knoxville McGhee Tyson

Sat 11/8

1:52 pm-11:44 pm

2 stops9h 52m

$482

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Fri 11/7

9:30 am-10:48 am

1 stop25h 18m

Knoxville McGhee Tyson

Mon 11/10

9:50 am-1:47 pm

1 stop3h 57m

$487

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Manchester, New Hampshire to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Manchester, New Hampshire, with most prices found around $323. If you aren’t able to travel during the month of August, then book flights to Knoxville from Manchester, New Hampshire during February instead. Flights to Knoxville in February, while not as cheap as those in August, still average around $354.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Manchester, New Hampshire to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $127. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from Manchester, New Hampshire to Knoxville for around $225.

What is the cheapest time of day to depart on your flight to Knoxville?

In the morning is the cheapest time of day to fly from Manchester, New Hampshire to Knoxville when you can find flight prices for as low as $195. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $604.

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Manchester, New Hampshire when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $499 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Manchester, New Hampshire for as low as $292 on momondo.

When to book flights from Manchester, New Hampshire to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Knoxville (MHT to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Knoxville

Direct flights

None
There are no direct flights from Manchester, New Hampshire to Knoxville. There are no popular flight routes from Manchester, New Hampshire to Knoxville.
Search flight deals

  • How far is Manchester to Knoxville McGhee Tyson by plane?

    A flight from Manchester to Knoxville McGhee Tyson will travel around 821.5 mi. In terms of flight time, this usually takes a little over 4h 16m.

  • When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester, New Hampshire to Knoxville?

Best airlines flying from Manchester, New Hampshire to Knoxville

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $248Free CancellationRating
7.4
8,988 reviews
Search United Airlines flights
American AirlinesPriceFrom $248Free CancellationRating
7.2
11,029 reviews
Search American Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Manchester.

Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Knoxville.

I’m not ready to book a flight from Manchester to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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