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Cheap flights from Manchester, New Hampshire to Knoxville from $148

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Knoxville departing on 7/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Manchester, New Hampshire to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
2:42 pm - 8:07 pm
MHT
-
TYS
5h 25m
1 stop
American Airlines Logo
7:31 pm - 11:52 pm
TYS
-
MHT
4h 21m
1 stop
$298American Airlines
Thu, Aug 6 - Tue, Aug 11
Southwest Logo
3:05 pm - 7:50 pm
MHT
-
TYS
4h 45m
1 stop
Southwest Logo
8:50 am - 7:40 pm
TYS
-
MHT
10h 50m
1 stop
$300Southwest
Wed, Sep 23 - Sat, Sep 26
Southwest Logo
6:45 am - 2:40 pm
MHT
-
TYS
7h 55m
1 stop
Southwest Logo
1:00 pm - 9:50 pm
TYS
-
MHT
8h 50m
1 stop
$312Southwest
Sat, Sep 12 - Thu, Sep 17
Southwest Logo
5:45 am - 2:40 pm
MHT
-
TYS
8h 55m
2 stops
Southwest Logo
1:00 pm - 9:50 pm
TYS
-
MHT
8h 50m
1 stop
$317Southwest
Sat, Sep 12 - Thu, Sep 17
American Airlines Logo
6:00 am - 9:33 pm
MHT
-
TYS
15h 33m
1 stop
American Airlines Logo
6:10 pm - 10:51 pm
TYS
-
MHT
4h 41m
1 stop
$331American Airlines
Sat, Jul 25 - Tue, Jul 28
American Airlines Logo
7:05 am - 1:31 pm
MHT
-
TYS
6h 26m
1 stop
American Airlines Logo
10:57 am - 4:42 pm
TYS
-
MHT
5h 45m
1 stop
$336American Airlines
Wed, Sep 2 - Sun, Sep 6
American Airlines Logo
7:05 am - 1:31 pm
MHT
-
TYS
6h 26m
1 stop
American Airlines Logo
6:32 pm - 11:36 pm
TYS
-
MHT
5h 04m
1 stop
$339American Airlines
Fri, Aug 14 - Mon, Aug 17
Southwest Logo
5:40 am - 5:10 pm
MHT
-
TYS
11h 30m
2 stops
Southwest Logo
8:05 am - 2:20 pm
TYS
-
MHT
6h 15m
1 stop
$341Southwest
Fri, Sep 11 - Wed, Sep 16
Southwest Logo
7:45 am - 6:55 pm
MHT
-
TYS
11h 10m
2 stops
Southwest Logo
8:50 am - 7:40 pm
TYS
-
MHT
10h 50m
1 stop
$347Southwest
Wed, Sep 23 - Sat, Sep 26
United Airlines Logo
7:37 pm - 11:54 pm
MHT
-
TYS
4h 17m
1 stop
United Airlines Logo
7:00 am - 7:00 pm
TYS
-
MHT
12h 00m
2 stops
$348United Airlines
Thu, Aug 6 - Tue, Aug 11

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United Airlines flights from Manchester, New Hampshire to Knoxville

Our best United Airlines deals on Manchester, New Hampshire to Knoxville flight tickets
United Airlines
Aug 6
MHT7:37 pmManchester
4h 17m
1 stop
TYS11:54 pmKnoxville McGhee Tyson
Aug 11
TYS7:00 amKnoxville McGhee Tyson
12h 00m
2 stops
MHT7:00 pmManchester
$348
United Airlines
Sep 2
MHT9:25 amManchester
11h 28m
2 stops
TYS8:53 pmKnoxville McGhee Tyson
Sep 6
TYS9:45 amKnoxville McGhee Tyson
4h 23m
1 stop
MHT2:08 pmManchester
$358
United Airlines
Sep 2
MHT9:25 amManchester
11h 28m
2 stops
TYS8:53 pmKnoxville McGhee Tyson
Sep 6
TYS7:00 amKnoxville McGhee Tyson
12h 00m
2 stops
MHT7:00 pmManchester
$363

American Airlines flights from Manchester, New Hampshire to Knoxville

Our best American Airlines deals on Manchester, New Hampshire to Knoxville flight tickets
American Airlines
Aug 6
MHT2:42 pmManchester
5h 25m
1 stop
TYS8:07 pmKnoxville McGhee Tyson
Aug 11
TYS7:31 pmKnoxville McGhee Tyson
4h 21m
1 stop
MHT11:52 pmManchester
$298
American Airlines
Jul 25
MHT6:00 amManchester
15h 33m
1 stop
TYS9:33 pmKnoxville McGhee Tyson
Jul 28
TYS6:10 pmKnoxville McGhee Tyson
4h 41m
1 stop
MHT10:51 pmManchester
$331
American Airlines
Sep 2
MHT7:05 amManchester
6h 26m
1 stop
TYS1:31 pmKnoxville McGhee Tyson
Sep 6
TYS10:57 amKnoxville McGhee Tyson
5h 45m
1 stop
MHT4:42 pmManchester
$336

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 30, 2026.
Use the filters below to find and compare flights from Manchester, New Hampshire to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 8/6

2:42 pm-8:07 pm

1 stop5h 25m

Knoxville McGhee Tyson

Tue 8/11

7:31 pm-11:52 pm

1 stop4h 21m

$298

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 9/23

3:05 pm-7:50 pm

1 stop4h 45m

Knoxville McGhee Tyson

Sat 9/26

8:50 am-7:40 pm

1 stop10h 50m

$300

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sat 9/12

6:45 am-2:40 pm

1 stop7h 55m

Knoxville McGhee Tyson

Thu 9/17

1:00 pm-9:50 pm

1 stop8h 50m

$312

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sat 9/12

5:45 am-2:40 pm

2 stops8h 55m

Knoxville McGhee Tyson

Thu 9/17

1:00 pm-9:50 pm

1 stop8h 50m

$317

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Sat 7/25

6:00 am-9:33 pm

1 stop15h 33m

Knoxville McGhee Tyson

Tue 7/28

6:10 pm-10:51 pm

1 stop4h 41m

$331

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 9/2

7:05 am-1:31 pm

1 stop6h 26m

Knoxville McGhee Tyson

Sun 9/6

10:57 am-4:42 pm

1 stop5h 45m

$336

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Fri 8/14

7:05 am-1:31 pm

1 stop6h 26m

Knoxville McGhee Tyson

Mon 8/17

6:32 pm-11:36 pm

1 stop5h 04m

$339

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Fri 9/11

5:40 am-5:10 pm

2 stops11h 30m

Knoxville McGhee Tyson

Wed 9/16

8:05 am-2:20 pm

1 stop6h 15m

$341

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Wed 9/23

7:45 am-6:55 pm

2 stops11h 10m

Knoxville McGhee Tyson

Sat 9/26

8:50 am-7:40 pm

1 stop10h 50m

$347

ManchesterKnoxville

MHT - TYS

MHTTYS

Manchester

Thu 8/6

7:37 pm-11:54 pm

1 stop4h 17m

Knoxville McGhee Tyson

Tue 8/11

7:00 am-7:00 pm

2 stops12h 00m

$348

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Manchester, New Hampshire to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Manchester, New Hampshire and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Manchester, New Hampshire, with most prices found around $323. If you aren’t able to travel during the month of August, then book flights to Knoxville from Manchester, New Hampshire during January instead. Flights to Knoxville in January, while not as cheap as those in August, still average around $422.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Manchester, New Hampshire to Knoxville is on a Friday. Travelers who choose to depart for Knoxville on a Friday will often find tickets for as low as $192. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Manchester, New Hampshire to Knoxville for around $352.

How far in advance should I book a flight from Manchester, New Hampshire to Knoxville?

You are more likely to see cheaper flights to Knoxville from Manchester, New Hampshire when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $454 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Manchester, New Hampshire for as low as $352 on momondo.

Can stopping save me money on Manchester, New Hampshire to Knoxville flights?

You could potentially save up to 9% on your flight if you consider stops on a Manchester, New Hampshire to Knoxville flight.

When to book flights from Manchester, New Hampshire to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Knoxville (MHT to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Knoxville

Fastest flight time

4h 17m

Direct flights

None
The fastest flight from Manchester, New Hampshire to Knoxville takes 4h 17m
There are no direct flights from Manchester, New Hampshire to Knoxville. There are no popular flight routes from Manchester, New Hampshire to Knoxville.
Search flight deals

Frequently asked questions about flying from Manchester, New Hampshire to Knoxville

  • How far is Manchester to Knoxville McGhee Tyson by plane?

    A flight from Manchester to Knoxville McGhee Tyson will travel around 821.5 mi. In terms of flight time, this usually takes a little over 4h 17m.

  • When did momondo last update prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Manchester Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Manchester Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Manchester Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Manchester Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Manchester, New Hampshire to Knoxville?

Best airlines flying from Manchester, New Hampshire to Knoxville

Compare and see reviews for airlines that fly from Manchester, New Hampshire to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.1
11,762 reviews
Search American Airlines flights
United AirlinesPriceFrom $285Free CancellationRating
7.4
9,901 reviews
Search United Airlines flights
SouthwestPriceFrom $325Free CancellationRating
7.9
4,247 reviews
Search Southwest flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Murphy
Crossville
Oak Ridge
Kodak
Newport
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Manchester.

Can I find flights from Manchester to Knoxville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Knoxville from Manchester which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Manchester to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Manchester to Knoxville.

I’m not ready to book a flight from Manchester to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Manchester are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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