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Cheap flights from Maine to Knoxville from $45

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Maine to Knoxville departing on 5/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Maine to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
10:38 am - 1:01 pm
BOS
-
TYS
2h 23mnonstop
Allegiant Air Logo
7:30 am - 9:48 am
TYS
-
BOS
2h 18mnonstop
$140Allegiant Air
Thu, Jun 4 - Sun, Jun 7
Allegiant Air Logo
10:46 am - 10:18 pm
BOS
-
TYS
11h 32m
1 stop
Allegiant Air Logo
7:30 am - 9:40 am
TYS
-
BOS
2h 10mnonstop
$141Allegiant Air
Sat, May 30 - Sun, May 31
Allegiant Air Logo
9:06 am - 11:35 am
BOS
-
TYS
2h 29mnonstop
Allegiant Air Logo
6:00 am - 8:16 am
TYS
-
BOS
2h 16mnonstop
$145Allegiant Air
Sun, Apr 12 - Thu, Apr 16
Multiple Airlines Logo
5:45 am - 10:36 am
BOS
-
TYS
28h 51m
1 stop
Multiple Airlines Logo
6:00 am - 8:16 am
TYS
-
BOS
2h 16mnonstop
$150Multiple Airlines
Tue, Apr 14 - Sat, Apr 18
Multiple Airlines Logo
5:45 am - 10:36 am
BOS
-
TYS
28h 51m
1 stop
Multiple Airlines Logo
6:00 am - 8:16 am
TYS
-
BOS
2h 16mnonstop
$160Multiple Airlines
Tue, Apr 14 - Thu, Apr 16
American Airlines Logo
6:00 am - 1:11 pm
PWM
-
TYS
7h 11m
1 stop
American Airlines Logo
6:00 am - 10:07 am
TYS
-
PWM
4h 07m
1 stop
$311American Airlines
Wed, Apr 29 - Tue, May 5
American Airlines Logo
11:17 am - 7:45 pm
BGR
-
TYS
8h 28m
2 stops
American Airlines Logo
10:35 am - 4:35 pm
TYS
-
BGR
6h 00m
1 stop
$324American Airlines
Sat, Aug 22 - Sat, Aug 29
Delta Logo
6:02 am - 11:04 am
PWM
-
TYS
5h 02m
1 stop
Delta Logo
6:00 am - 10:23 am
TYS
-
PWM
4h 23m
1 stop
$325Delta
Wed, May 13 - Fri, May 15
Delta Logo
12:49 pm - 8:35 pm
BGR
-
TYS
7h 46m
1 stop
Delta Logo
5:30 pm - 11:31 pm
TYS
-
BGR
6h 01m
1 stop
$334Delta
Wed, Apr 15 - Mon, Apr 20
United Airlines Logo
11:09 am - 10:34 pm
PWM
-
TYS
11h 25m
2 stops
United Airlines Logo
7:00 am - 2:14 pm
TYS
-
PWM
7h 14m
1 stop
$344United Airlines
Sat, Apr 25 - Sat, May 2

Allegiant Air flights from Maine to Knoxville

Our best Allegiant Air deals on Maine to Knoxville flight tickets
Allegiant Air
Jun 4
BOS10:38 amBoston Logan Intl
2h 23m
TYS1:01 pmKnoxville McGhee Tyson
Jun 7
TYS7:30 amKnoxville McGhee Tyson
2h 18m
BOS9:48 amBoston Logan Intl
$140
Allegiant Air
May 30
BOS10:46 amBoston Logan Intl
11h 32m
1 stop
TYS10:18 pmKnoxville McGhee Tyson
May 31
TYS7:30 amKnoxville McGhee Tyson
2h 10m
BOS9:40 amBoston Logan Intl
$141
Allegiant Air
Apr 12
BOS9:06 amBoston Logan Intl
2h 29m
TYS11:35 amKnoxville McGhee Tyson
Apr 16
TYS6:00 amKnoxville McGhee Tyson
2h 16m
BOS8:16 amBoston Logan Intl
$145

Delta flights from Maine to Knoxville

Our best Delta deals on Maine to Knoxville flight tickets
Delta
May 13
PWM6:02 amPortland
5h 02m
1 stop
TYS11:04 amKnoxville McGhee Tyson
May 15
TYS6:00 amKnoxville McGhee Tyson
4h 23m
1 stop
PWM10:23 amPortland
$325
Delta
Apr 15
BGR12:49 pmBangor
7h 46m
1 stop
TYS8:35 pmKnoxville McGhee Tyson
Apr 20
TYS5:30 pmKnoxville McGhee Tyson
6h 01m
1 stop
BGR11:31 pmBangor
$334
Delta
Apr 29
PWM11:42 amPortland
5h 07m
1 stop
TYS4:49 pmKnoxville McGhee Tyson
May 5
TYS5:30 pmKnoxville McGhee Tyson
5h 54m
1 stop
PWM11:24 pmPortland
$339

momondo Fare Finder

 
Customize your flight search to find flights from Maine to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Maine to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 6/4

10:38 am-1:01 pm

Nonstop2h 23m

Knoxville McGhee Tyson

Sun 6/7

7:30 am-9:48 am

Nonstop2h 18m

$140

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Sat 5/30

10:46 am-10:18 pm

1 stop11h 32m

Knoxville McGhee Tyson

Sun 5/31

7:30 am-9:40 am

Nonstop2h 10m

$141

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Sun 4/12

9:06 am-11:35 am

Nonstop2h 29m

Knoxville McGhee Tyson

Thu 4/16

6:00 am-8:16 am

Nonstop2h 16m

$145

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Tue 4/14

5:45 am-10:36 am

1 stop28h 51m

Knoxville McGhee Tyson

Sat 4/18

6:00 am-8:16 am

Nonstop2h 16m

$150

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Tue 4/14

5:45 am-10:36 am

1 stop28h 51m

Knoxville McGhee Tyson

Thu 4/16

6:00 am-8:16 am

Nonstop2h 16m

$160

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Wed 4/29

6:00 am-1:11 pm

1 stop7h 11m

Knoxville McGhee Tyson

Tue 5/5

6:00 am-10:07 am

1 stop4h 07m

$311

BangorKnoxville

BGR - TYS

BGRTYS

Bangor

Sat 8/22

11:17 am-7:45 pm

2 stops8h 28m

Knoxville McGhee Tyson

Sat 8/29

10:35 am-4:35 pm

1 stop6h 00m

$324

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Wed 5/13

6:02 am-11:04 am

1 stop5h 02m

Knoxville McGhee Tyson

Fri 5/15

6:00 am-10:23 am

1 stop4h 23m

$325

BangorKnoxville

BGR - TYS

BGRTYS

Bangor

Wed 4/15

12:49 pm-8:35 pm

1 stop7h 46m

Knoxville McGhee Tyson

Mon 4/20

5:30 pm-11:31 pm

1 stop6h 01m

$334

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Sat 4/25

11:09 am-10:34 pm

2 stops11h 25m

Knoxville McGhee Tyson

Sat 5/2

7:00 am-2:14 pm

1 stop7h 14m

$344

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Maine to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Maine, with most prices found around $285. If you aren’t able to travel during the month of January, then book flights to Knoxville from Maine during August instead. Flights to Knoxville in August, while not as cheap as those in January, still average around $288.

Can stopping save me money on Maine to Knoxville flights?

You could potentially save up to 52% on your flight if you consider stops on a Maine to Knoxville flight.

Cheap Maine to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Maine to Knoxville

Fastest flight time

2h 22m

Direct flights

Mon, Wed, Fri and Sun

Airports in Knoxville

1 airport
The fastest flight from Maine to Knoxville takes 2h 22m
Direct flights go from Maine to Knoxville on Monday, Wednesday, Friday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Knoxville. From Maine there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

Frequently asked questions about flying from Maine to Knoxville

  • When did momondo last update prices for flights from Maine to Knoxville McGhee Tyson Airport?

    Prices for flights from Maine to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Maine to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Maine to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Maine to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Maine to Knoxville

Compare and see reviews for airlines that fly from Maine to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $258Free CancellationRating
7.1
11,544 reviews
Search American Airlines flights
DeltaPriceFrom $258Free CancellationRating
7.9
8,368 reviews
Search Delta flights
United AirlinesPriceFrom $278Free CancellationRating
7.4
9,529 reviews
Search United Airlines flights
SouthwestPriceFrom $293Free CancellationRating
8.0
4,335 reviews
Search Southwest flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Alcoa
Murphy
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Maine to Knoxville?

Finding the right flight to Knoxville from Maine is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Maine to Knoxville with flexible booking policies on momondo?

Flights from Maine to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Maine to Knoxville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Knoxville from Maine.

I’m not ready to book a flight from Maine to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Maine to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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