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Cheap flights from Maine to Florence from $359

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Maine to Florence departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Maine to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:15 pm - 5:21 pm
BOS
-
FLO
5h 06m
1 stop
American Airlines Logo
6:15 am - 1:03 pm
FLO
-
BOS
6h 48m
1 stop
$359American Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
4:10 pm - 11:08 pm
BOS
-
FLO
6h 58m
1 stop
American Airlines Logo
6:15 am - 2:44 pm
FLO
-
BOS
8h 29m
2 stops
$364American Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
6:52 pm - 11:57 pm
BOS
-
FLO
5h 05m
1 stop
American Airlines Logo
6:20 pm - 10:51 pm
FLO
-
BOS
4h 31m
1 stop
$369American Airlines
Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
10:00 am - 5:50 pm
BOS
-
FLO
7h 50m
2 stops
American Airlines Logo
6:20 pm - 10:51 pm
FLO
-
BOS
4h 31m
1 stop
$374American Airlines
Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
10:56 am - 5:50 pm
BOS
-
FLO
6h 54m
1 stop
American Airlines Logo
6:20 pm - 10:51 pm
FLO
-
BOS
4h 31m
1 stop
$419American Airlines
Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
3:49 pm - 11:57 pm
BOS
-
FLO
8h 08m
2 stops
American Airlines Logo
6:20 pm - 10:51 pm
FLO
-
BOS
4h 31m
1 stop
$424American Airlines
Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
10:59 am - 5:50 pm
BOS
-
FLO
6h 51m
2 stops
American Airlines Logo
6:20 pm - 11:59 pm
FLO
-
BOS
5h 39m
2 stops
$429American Airlines
Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
10:56 am - 5:50 pm
BOS
-
FLO
6h 54m
1 stop
American Airlines Logo
6:20 pm - 10:51 pm
FLO
-
BOS
4h 31m
1 stop
$439American Airlines
Wed, Mar 18 - Mon, Mar 23
American Airlines Logo
9:59 am - 5:50 pm
BOS
-
FLO
7h 51m
2 stops
American Airlines Logo
5:16 am - 11:36 am
FLO
-
BOS
6h 20m
1 stop
$444American Airlines
Wed, Mar 18 - Mon, Mar 23
American Airlines Logo
8:00 am - 5:50 pm
BOS
-
FLO
9h 50m
2 stops
American Airlines Logo
6:20 pm - 11:59 pm
FLO
-
BOS
5h 39m
2 stops
$449American Airlines
Thu, Mar 5 - Mon, Mar 9

American Airlines flights from Maine to Florence, South Carolina

Our best American Airlines deals on Maine to Florence, South Carolina flight tickets
American Airlines
Feb 25
BOS12:15 pmBoston Logan Intl
5h 06m
1 stop
FLO5:21 pmFlorence
Mar 4
FLO6:15 amFlorence
6h 48m
1 stop
BOS1:03 pmBoston Logan Intl
$359
American Airlines
Feb 25
BOS4:10 pmBoston Logan Intl
6h 58m
1 stop
FLO11:08 pmFlorence
Mar 4
FLO6:15 amFlorence
8h 29m
2 stops
BOS2:44 pmBoston Logan Intl
$364
American Airlines
Feb 11
BOS8:00 amBoston Logan Intl
9h 09m
2 stops
FLO5:09 pmFlorence
Feb 18
FLO6:15 amFlorence
7h 57m
2 stops
BOS2:12 pmBoston Logan Intl
$369

momondo Fare Finder

 
Customize your flight search to find flights from Maine to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Maine to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Wed 2/25

12:15 pm-5:21 pm

1 stop5h 06m

Florence

Wed 3/4

6:15 am-1:03 pm

1 stop6h 48m

$359

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Wed 2/25

4:10 pm-11:08 pm

1 stop6h 58m

Florence

Wed 3/4

6:15 am-2:44 pm

2 stops8h 29m

$364

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 3/5

6:52 pm-11:57 pm

1 stop5h 05m

Florence

Mon 3/9

6:20 pm-10:51 pm

1 stop4h 31m

$369

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 3/5

10:00 am-5:50 pm

2 stops7h 50m

Florence

Mon 3/9

6:20 pm-10:51 pm

1 stop4h 31m

$374

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 3/5

10:56 am-5:50 pm

1 stop6h 54m

Florence

Mon 3/9

6:20 pm-10:51 pm

1 stop4h 31m

$419

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 3/5

3:49 pm-11:57 pm

2 stops8h 08m

Florence

Mon 3/9

6:20 pm-10:51 pm

1 stop4h 31m

$424

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 3/5

10:59 am-5:50 pm

2 stops6h 51m

Florence

Mon 3/9

6:20 pm-11:59 pm

2 stops5h 39m

$429

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Wed 3/18

10:56 am-5:50 pm

1 stop6h 54m

Florence

Mon 3/23

6:20 pm-10:51 pm

1 stop4h 31m

$439

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Wed 3/18

9:59 am-5:50 pm

2 stops7h 51m

Florence

Mon 3/23

5:16 am-11:36 am

1 stop6h 20m

$444

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 3/5

8:00 am-5:50 pm

2 stops9h 50m

Florence

Mon 3/9

6:20 pm-11:59 pm

2 stops5h 39m

$449

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Maine to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Maine to Florence?

American Airlines is the most popular carrier operating from Maine to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Breeze Airways and Southwest are the top three most popular airlines that fly to Florence, South Carolina from Maine according to our data. American Airlines is the first choice among our users, with 61% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 4 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Maine to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Maine to Florence, South Carolina

Fastest flight time

5h 02m

Direct flights

None
The fastest flight from Maine to Florence, South Carolina takes 5h 02m
There are no direct flights from Maine to Florence, South Carolina. There are no popular flight routes from Maine to Florence, South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Maine to Florence Airport?

    Prices for flights from Maine to Florence Airport are updated daily.

  • How many operators does momondo search for flights from Maine to Florence Airport?

  • How old do you have to be to fly from Maine to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Maine to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Darlington
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Maine to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Maine.

Can I find flights from Maine to Florence with flexible booking policies on momondo?

Yes. All flights to Florence from Maine on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Maine to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Maine.

I’m not ready to book a flight from Maine to Florence right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florence, momondo offers a useful price alert feature which will track prices for flights to Florence from Maine and alert you when they change.

An easier way to manage your Florence, South Carolina trip

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