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Cheap flights from Maine to Florence from $281

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Maine to Florence departing on 7/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Maine to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:05 am - 2:10 pm
BOS
-
FLO
6h 05m
1 stop
American Airlines Logo
5:17 am - 9:19 am
FLO
-
BOS
4h 02m
1 stop
$379American Airlines
Tue, Jul 7 - Tue, Jul 14
American Airlines Logo
7:00 am - 2:10 pm
BOS
-
FLO
7h 10m
1 stop
American Airlines Logo
2:35 pm - 8:10 pm
FLO
-
BOS
5h 35m
1 stop
$409American Airlines
Sat, Jul 4 - Fri, Jul 10
American Airlines Logo
8:00 am - 2:10 pm
BOS
-
FLO
6h 10m
1 stop
American Airlines Logo
6:24 am - 12:43 pm
FLO
-
BOS
6h 19m
1 stop
$419American Airlines
Sun, Sep 13 - Sat, Sep 26
American Airlines Logo
5:45 pm - 10:59 pm
BOS
-
FLO
5h 14m
1 stop
American Airlines Logo
12:51 pm - 7:18 pm
FLO
-
BOS
6h 27m
1 stop
$425American Airlines
Mon, Aug 31 - Sat, Dec 19
American Airlines Logo
6:31 pm - 2:10 pm
BOS
-
FLO
19h 39m
2 stops
American Airlines Logo
5:17 am - 9:19 am
FLO
-
BOS
4h 02m
1 stop
$494American Airlines
Sat, Jul 4 - Fri, Jul 10
American Airlines Logo
4:47 pm - 10:00 pm
BOS
-
FLO
5h 13m
1 stop
American Airlines Logo
2:35 pm - 8:10 pm
FLO
-
BOS
5h 35m
1 stop
$499American Airlines
Thu, Jun 25 - Fri, Jul 3
American Airlines Logo
6:53 pm - 11:57 pm
BOS
-
FLO
5h 04m
1 stop
American Airlines Logo
6:24 am - 4:55 pm
FLO
-
BOS
10h 31m
2 stops
$506American Airlines
Sun, Sep 13 - Sat, Sep 26
American Airlines Logo
5:57 am - 10:26 am
BOS
-
FLO
4h 29m
1 stop
American Airlines Logo
11:07 am - 3:15 pm
FLO
-
BOS
4h 08m
1 stop
$534American Airlines
Fri, Oct 9 - Wed, Oct 14
American Airlines Logo
3:38 pm - 10:59 pm
BOS
-
FLO
7h 21m
1 stop
American Airlines Logo
12:51 pm - 10:50 pm
FLO
-
BOS
9h 59m
2 stops
$564American Airlines
Mon, Aug 31 - Sat, Dec 19
American Airlines Logo
2:04 pm - 11:37 pm
BOS
-
FLO
9h 33m
2 stops
American Airlines Logo
2:35 pm - 8:10 pm
FLO
-
BOS
5h 35m
1 stop
$572American Airlines
Tue, Jul 7 - Tue, Jul 14

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American Airlines flights from Maine to Florence, South Carolina

Our best American Airlines deals on Maine to Florence, South Carolina flight tickets
American Airlines
Jul 7
BOS8:05 amBoston Logan Intl
6h 05m
1 stop
FLO2:10 pmFlorence
Jul 14
FLO5:17 amFlorence
4h 02m
1 stop
BOS9:19 amBoston Logan Intl
$379
American Airlines
Jul 7
BOS6:55 pmBoston Logan Intl
4h 42m
1 stop
FLO11:37 pmFlorence
Jul 13
FLO2:35 pmFlorence
5h 35m
1 stop
BOS8:10 pmBoston Logan Intl
$409
American Airlines
Sep 13
BOS8:00 amBoston Logan Intl
6h 10m
1 stop
FLO2:10 pmFlorence
Sep 26
FLO6:24 amFlorence
6h 19m
1 stop
BOS12:43 pmBoston Logan Intl
$419

momondo Fare Finder

 
Customize your flight search to find flights from Maine to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from Maine to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Tue 7/7

8:05 am-2:10 pm

1 stop6h 05m

Florence

Tue 7/14

5:17 am-9:19 am

1 stop4h 02m

$379

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sat 7/4

7:00 am-2:10 pm

1 stop7h 10m

Florence

Fri 7/10

2:35 pm-8:10 pm

1 stop5h 35m

$409

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sun 9/13

8:00 am-2:10 pm

1 stop6h 10m

Florence

Sat 9/26

6:24 am-12:43 pm

1 stop6h 19m

$419

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Mon 8/31

5:45 pm-10:59 pm

1 stop5h 14m

Florence

Sat 12/19

12:51 pm-7:18 pm

1 stop6h 27m

$425

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sat 7/4

6:31 pm-2:10 pm

2 stops19h 39m

Florence

Fri 7/10

5:17 am-9:19 am

1 stop4h 02m

$494

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 6/25

4:47 pm-10:00 pm

1 stop5h 13m

Florence

Fri 7/3

2:35 pm-8:10 pm

1 stop5h 35m

$499

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sun 9/13

6:53 pm-11:57 pm

1 stop5h 04m

Florence

Sat 9/26

6:24 am-4:55 pm

2 stops10h 31m

$506
Quickest round-trip

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Fri 10/9

5:57 am-10:26 am

1 stop4h 29m

Florence

Wed 10/14

11:07 am-3:15 pm

1 stop4h 08m

$534

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Mon 8/31

3:38 pm-10:59 pm

1 stop7h 21m

Florence

Sat 12/19

12:51 pm-10:50 pm

2 stops9h 59m

$564

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Tue 7/7

2:04 pm-11:37 pm

2 stops9h 33m

Florence

Tue 7/14

2:35 pm-8:10 pm

1 stop5h 35m

$572

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
1
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See travel insights to Florence from

How to get the cheapest flight ticket from Maine to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Maine to Florence?

American Airlines is the most popular carrier operating from Maine to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Breeze Airways and Southwest are the top three most popular airlines that fly to Florence, South Carolina from Maine according to our data. American Airlines is the first choice among our users, with 69% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 5 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Maine to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Maine to Florence, South Carolina

Fastest flight time

4h 29m

Direct flights

None
The fastest flight from Maine to Florence, South Carolina takes 4h 29m
There are no direct flights from Maine to Florence, South Carolina. There are no popular flight routes from Maine to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Maine to Florence, South Carolina

  • When did momondo last update prices for flights from Maine to Florence Airport?

    Prices for flights from Maine to Florence Airport are updated daily.

  • How many operators does momondo search for flights from Maine to Florence Airport?

  • How old do you have to be to fly from Maine to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Maine to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Maine to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Maine.

Can I find flights from Maine to Florence with flexible booking policies on momondo?

Yes. All flights to Florence from Maine on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Maine to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Maine.

I’m not ready to book a flight from Maine to Florence right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Florence, momondo offers a useful price alert feature which will track prices for flights to Florence from Maine and alert you when they change.

An easier way to manage your Florence, South Carolina trip

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