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Cheap flights from Louisville to Panama City from $155

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama City departing on 8/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Louisville to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:12 pm - 10:40 pm
SDF
-
ECP
4h 28m
1 stop
American Airlines Logo
5:48 pm - 11:11 pm
ECP
-
SDF
4h 23m
1 stop
$309American Airlines
Thu, Aug 20 - Mon, Aug 24
American Airlines Logo
8:18 pm - 11:53 pm
SDF
-
ECP
4h 35m
1 stop
American Airlines Logo
5:41 pm - 11:38 pm
ECP
-
SDF
4h 57m
1 stop
$309American Airlines
Wed, Oct 28 - Mon, Nov 2
Delta Logo
6:00 am - 8:37 am
SDF
-
ECP
3h 37m
1 stop
Delta Logo
1:34 pm - 8:59 pm
ECP
-
SDF
6h 25m
1 stop
$309Delta
Thu, Nov 12 - Thu, Nov 12
Delta Logo
10:13 am - 12:49 pm
SDF
-
ECP
3h 36m
1 stop
Delta Logo
7:00 am - 11:56 am
ECP
-
SDF
3h 56m
1 stop
$309Delta
Tue, Nov 10 - Thu, Nov 12
Southwest Logo
3:20 pm - 7:00 pm
SDF
-
ECP
4h 40m
1 stop
Southwest Logo
10:40 am - 5:20 pm
ECP
-
SDF
5h 40m
1 stop
$309Southwest
Mon, Aug 31 - Sat, Sep 5
United Airlines Logo
10:13 am - 3:14 pm
SDF
-
ECP
6h 01m
1 stop
United Airlines Logo
6:20 am - 1:09 pm
ECP
-
SDF
5h 49m
1 stop
$309United Airlines
Sat, Oct 3 - Sat, Oct 10
United Airlines Logo
9:04 am - 1:03 pm
SDF
-
ECP
4h 59m
1 stop
United Airlines Logo
2:50 pm - 10:10 pm
ECP
-
SDF
6h 20m
1 stop
$309United Airlines
Mon, Oct 5 - Sat, Oct 10
Southwest Logo
7:55 am - 10:10 am
SDF
-
ECP
3h 15m
1 stop
Southwest Logo
1:30 pm - 10:00 pm
ECP
-
SDF
7h 30m
2 stops
$314Southwest
Sun, Sep 6 - Fri, Sep 11
Southwest Logo
8:20 am - 1:55 pm
SDF
-
ECP
6h 35m
1 stop
Southwest Logo
10:30 am - 5:30 pm
ECP
-
SDF
6h 00m
2 stops
$314Southwest
Sat, Sep 12 - Sat, Sep 19
American Airlines Logo
7:12 pm - 10:40 pm
SDF
-
ECP
4h 28m
1 stop
American Airlines Logo
5:48 pm - 11:11 pm
ECP
-
SDF
4h 23m
1 stop
$339American Airlines
Fri, Aug 21 - Mon, Aug 24

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Delta flights from Louisville to Panama City, Florida

Our best Delta deals on Louisville to Panama City, Florida flight tickets
Delta
Sep 9
SDF6:00 amLouisville Intl
3h 16m
1 stop
ECP8:16 amPanama City NW Florida Beaches
Sep 12
ECP7:35 amPanama City NW Florida Beaches
6h 23m
1 stop
SDF2:58 pmLouisville Intl
$313
Delta
Oct 30
SDF1:59 pmLouisville Intl
3h 38m
1 stop
ECP4:37 pmPanama City NW Florida Beaches
Nov 4
ECP6:00 amPanama City NW Florida Beaches
3h 21m
1 stop
SDF10:21 amLouisville Intl
$324
Delta
Oct 1
SDF7:55 pmLouisville Intl
4h 30m
1 stop
ECP11:25 pmPanama City NW Florida Beaches
Oct 5
ECP4:35 pmPanama City NW Florida Beaches
6h 24m
1 stop
SDF11:59 pmLouisville Intl
$339

Southwest flights from Louisville to Panama City, Florida

Our best Southwest deals on Louisville to Panama City, Florida flight tickets
Southwest
Aug 31
SDF6:45 amLouisville Intl
3h 40m
1 stop
ECP9:25 amPanama City NW Florida Beaches
Sep 5
ECP10:30 amPanama City NW Florida Beaches
6h 00m
2 stops
SDF5:30 pmLouisville Intl
$314
Southwest
Aug 31
SDF2:15 pmLouisville Intl
5h 45m
2 stops
ECP7:00 pmPanama City NW Florida Beaches
Sep 5
ECP11:45 amPanama City NW Florida Beaches
8h 40m
2 stops
SDF9:25 pmLouisville Intl
$319
Southwest
Sep 12
SDF8:20 amLouisville Intl
6h 35m
1 stop
ECP1:55 pmPanama City NW Florida Beaches
Sep 15
ECP4:20 pmPanama City NW Florida Beaches
3h 20m
1 stop
SDF8:40 pmLouisville Intl
$326

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from Louisville to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Thu 8/20

7:12 pm-10:40 pm

1 stop4h 28m

Panama City NW Florida Beaches

Mon 8/24

5:48 pm-11:11 pm

1 stop4h 23m

$309

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Wed 10/28

8:18 pm-11:53 pm

1 stop4h 35m

Panama City NW Florida Beaches

Mon 11/2

5:41 pm-11:38 pm

1 stop4h 57m

$309

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Thu 11/12

6:00 am-8:37 am

1 stop3h 37m

Panama City NW Florida Beaches

Thu 11/12

1:34 pm-8:59 pm

1 stop6h 25m

$309
Quickest round-trip

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Tue 11/10

10:13 am-12:49 pm

1 stop3h 36m

Panama City NW Florida Beaches

Thu 11/12

7:00 am-11:56 am

1 stop3h 56m

$309

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Mon 8/31

3:20 pm-7:00 pm

1 stop4h 40m

Panama City NW Florida Beaches

Sat 9/5

10:40 am-5:20 pm

1 stop5h 40m

$309

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sat 10/3

10:13 am-3:14 pm

1 stop6h 01m

Panama City NW Florida Beaches

Sat 10/10

6:20 am-1:09 pm

1 stop5h 49m

$309

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Mon 10/5

9:04 am-1:03 pm

1 stop4h 59m

Panama City NW Florida Beaches

Sat 10/10

2:50 pm-10:10 pm

1 stop6h 20m

$309

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sun 9/6

7:55 am-10:10 am

1 stop3h 15m

Panama City NW Florida Beaches

Fri 9/11

1:30 pm-10:00 pm

2 stops7h 30m

$314

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sat 9/12

8:20 am-1:55 pm

1 stop6h 35m

Panama City NW Florida Beaches

Sat 9/19

10:30 am-5:30 pm

2 stops6h 00m

$314

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Fri 8/21

7:12 pm-10:40 pm

1 stop4h 28m

Panama City NW Florida Beaches

Mon 8/24

5:48 pm-11:11 pm

1 stop4h 23m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Louisville to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and Panama City, Florida?

Prices are currently low for flights on this route.

Typical prices usually range from $321 to $480.
The lowest price recently found on this route was $309.

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Louisville is in November. Flight prices, which tend to average around $301, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Panama City, Florida, with average flight prices from Louisville averaging around $366.

How far in advance should I book a flight from Louisville to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $432 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Louisville for as low as $300 on momondo.

How have Louisville to Panama City, Florida flight prices changed over time?

As of August 2026, prices for Louisville to Panama City, Florida flights are approximately 13% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Panama City, Florida (SDF to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama City, Florida

Fastest flight time

3h 14m

Direct flights

None
The fastest flight from Louisville to Panama City, Florida takes 3h 14m
There are no direct flights from Louisville to Panama City, Florida. There are no popular flight routes from Louisville to Panama City, Florida.
Search flight deals

Frequently asked questions about flying from Louisville to Panama City, Florida

  • How far is Louisville Intl to Panama City NW Florida Beaches by plane?

    A flight from Louisville Intl to Panama City NW Florida Beaches will travel around 558.6 mi. Typically, this will take 3h 14m by plane in normal conditions.

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The necessary travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Louisville to Panama City, Florida?

Best airlines flying from Louisville to Panama City, Florida

Compare and see reviews for airlines that fly from Louisville to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $250Free CancellationRating
7.8
8,481 reviews
Search Delta flights
American AirlinesPriceFrom $306Free CancellationRating
7.1
11,848 reviews
Search American Airlines flights
SouthwestPriceFrom $325Free CancellationRating
8.0
4,222 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Louisville to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Louisville to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to Panama City?

Once you have performed a search for Louisville to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Panama City, Florida trip

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