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Cheap flights from Louisville to Panama City from $149

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama City departing on 10/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Louisville to Panama City

Cheap round-trip flights

These are some of the best round-trip flight deals from Louisville to Panama City that have been recently found on momondo from popular airlines, departing in the coming months.
United Airlines Logo
7:00 am - 1:06 pmSDF-ECP
7h 06m1 stop
United Airlines Logo
3:20 pm - 9:52 pmECP-SDF
5h 32m1 stop
$257United Airlines
Find Deal
Wed, May 28 - Wed, Jun 4
American Airlines Logo
8:56 am - 3:59 pmSDF-ECP
8h 03m2 stops
American Airlines Logo
2:29 pm - 9:53 pmECP-SDF
6h 24m1 stop
$262American Airlines
Find Deal
Wed, May 28 - Tue, Jun 3
American Airlines Logo
5:45 am - 11:55 amSDF-ECP
7h 10m2 stops
American Airlines Logo
10:22 am - 8:13 pmECP-SDF
8h 51m2 stops
$267American Airlines
Find Deal
Wed, May 28 - Wed, Jun 4
American Airlines Logo
8:11 pm - 11:49 pmSDF-ECP
4h 38m1 stop
American Airlines Logo
3:55 pm - 10:47 pmECP-SDF
5h 52m1 stop
$272American Airlines
Find Deal
Thu, Jun 12 - Tue, Jun 17
Southwest Logo
2:15 pm - 10:10 pmSDF-ECP
8h 55m2 stops
Southwest Logo
6:15 am - 5:05 pmECP-SDF
9h 50m2 stops
$287Southwest
Find Deal
Wed, Jul 23 - Mon, Jul 28
Southwest Logo
2:15 pm - 10:10 pmSDF-ECP
8h 55m2 stops
Southwest Logo
6:15 am - 3:20 pmECP-SDF
8h 05m1 stop
$288Southwest
Find Deal
Wed, Jul 23 - Mon, Jul 28
American Airlines Logo
2:03 pm - 6:51 pmSDF-ECP
5h 48m1 stop
American Airlines Logo
6:55 pm - 12:30 amECP-SDF
4h 35m1 stop
$294American Airlines
Find Deal
Wed, Jul 23 - Mon, Jul 28
Delta Logo
6:00 am - 8:16 amSDF-ECP
3h 16m1 stop
Delta Logo
10:54 am - 5:10 pmECP-SDF
5h 16m1 stop
$297Delta
Find Deal
Sun, Jun 1 - Thu, Jun 5
American Airlines Logo
8:11 pm - 11:49 pmSDF-ECP
4h 38m1 stop
American Airlines Logo
2:39 pm - 10:17 pmECP-SDF
6h 38m1 stop
$302American Airlines
Find Deal
Sat, Jun 28 - Thu, Jul 3
Delta Logo
5:55 pm - 11:04 pmSDF-ECP
6h 09m1 stop
Delta Logo
6:59 pm - 12:05 amECP-SDF
4h 06m1 stop
$312Delta
Find Deal
Thu, May 29 - Sun, Jun 1

United Airlines flights from Louisville to Panama City, Florida

Our best United Airlines deals on Louisville to Panama City, Florida flight tickets
United Airlines
May 28
SDF7:00 amLouisville Intl
7h 06m
1 stop
ECP1:06 pmPanama City NW Florida Beaches
Jun 4
ECP3:20 pmPanama City NW Florida Beaches
5h 32m
1 stop
SDF9:52 pmLouisville Intl
United Airlines
Jun 1
SDF3:38 pmLouisville Intl
7h 22m
1 stop
ECP10:00 pmPanama City NW Florida Beaches
Jun 5
ECP11:10 amPanama City NW Florida Beaches
7h 29m
1 stop
SDF7:39 pmLouisville Intl
United Airlines
Jul 23
SDF7:00 amLouisville Intl
10h 21m
2 stops
ECP4:21 pmPanama City NW Florida Beaches
Jul 28
ECP8:40 amPanama City NW Florida Beaches
13h 18m
2 stops
SDF10:58 pmLouisville Intl

Southwest flights from Louisville to Panama City, Florida

Our best Southwest deals on Louisville to Panama City, Florida flight tickets
Southwest
Jul 23
SDF2:15 pmLouisville Intl
8h 55m
2 stops
ECP10:10 pmPanama City NW Florida Beaches
Jul 28
ECP6:15 amPanama City NW Florida Beaches
9h 50m
2 stops
SDF5:05 pmLouisville Intl
Southwest
Jul 23
SDF2:15 pmLouisville Intl
8h 55m
2 stops
ECP10:10 pmPanama City NW Florida Beaches
Jul 28
ECP6:15 amPanama City NW Florida Beaches
8h 05m
1 stop
SDF3:20 pmLouisville Intl
Southwest
May 17
SDF6:15 amLouisville Intl
4h 50m
1 stop
ECP10:05 amPanama City NW Florida Beaches
May 21
ECP2:55 pmPanama City NW Florida Beaches
4h 45m
1 stop
SDF8:40 pmLouisville Intl

See travel insights to Panama City from

How to get the cheapest flight ticket from Louisville to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Louisville is in August. Flight prices, which tend to average around $282, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Panama City, Florida, with average flight prices from Louisville averaging around $336.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Wednesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $336. On the other hand, Tuesday is the most expensive day to depart from Louisville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $375.

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Louisville when booking 15 weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $377 when searching 15 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Louisville for as low as $290 on momondo.

How have Louisville to Panama City, Florida flight prices changed over time?

As of May 2025, prices for Louisville to Panama City, Florida flights are approximately 20% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Panama City, Florida (SDF to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama City, Florida

Best Price Found

$149

Fastest flight time

3h 16m

Direct flights

None

Airports in Panama City, Florida

1 airport
The best one-way flight to Panama City, Florida from Louisville in the past 72 hours is $149. The best round-trip flight deal from Louisville to Panama City, Florida found on momondo in the last 72 hours is $257.
The fastest flight from Louisville to Panama City, Florida takes 3h 16m
There are no direct flights from Louisville to Panama City, Florida. Popular non-direct route for this connection is Louisville Intl Airport - Panama City NW Florida Beaches Airport.
There is 1 airport near Panama City, Florida: Panama City NW Florida Beaches (ECP)

  • How far is Louisville Intl to Panama City NW Florida Beaches by plane?

    A flight from Louisville Intl to Panama City NW Florida Beaches will travel around 558.6 mi. Typically, this will take 3h 16m by plane in normal conditions.

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The necessary travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Louisville to Panama City, Florida?


Best airlines flying from Louisville to Panama City, Florida

Compare and see reviews for airlines that fly from Louisville to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $224Free CancellationRating
8.0
7,934 reviews
Search Delta flights
American AirlinesPriceFrom $233Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $296Free CancellationRating
8.0
4,293 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Mexico Beach
Seaside
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Louisville to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Louisville to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to Panama City?

Once you have performed a search for Louisville to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.


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