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Cheap flights from Louisville to Panama City from $160

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama City departing on 6/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Louisville to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 10:54 am
SDF
-
ECP
5h 54m
1 stop
Delta Logo
5:08 pm - 12:32 am
ECP
-
SDF
6h 24m
1 stop
$319Delta
Tue, Jun 16 - Tue, Jun 23
Southwest Logo
4:40 pm - 6:55 pm
SDF
-
ECP
3h 15m
1 stop
Southwest Logo
2:25 pm - 11:10 pm
ECP
-
SDF
7h 45m
2 stops
$324Southwest
Tue, Jun 2 - Tue, Jun 9
American Airlines Logo
7:11 am - 3:46 pm
SDF
-
ECP
9h 35m
2 stops
American Airlines Logo
11:00 am - 9:41 pm
ECP
-
SDF
9h 41m
2 stops
$329American Airlines
Tue, Jun 2 - Tue, Jun 9
Southwest Logo
3:30 pm - 8:25 pm
SDF
-
ECP
5h 55m
2 stops
Southwest Logo
7:40 am - 8:25 pm
ECP
-
SDF
11h 45m
2 stops
$335Southwest
Wed, Jun 3 - Wed, Jun 10
Southwest Logo
4:40 pm - 6:55 pm
SDF
-
ECP
3h 15m
1 stop
Southwest Logo
5:25 pm - 9:40 pm
ECP
-
SDF
3h 15m
1 stop
$339Southwest
Tue, Jun 2 - Tue, Jun 9
American Airlines Logo
8:08 pm - 11:40 pm
SDF
-
ECP
4h 32m
1 stop
American Airlines Logo
7:05 am - 5:45 pm
ECP
-
SDF
9h 40m
2 stops
$340American Airlines
Thu, Jun 4 - Tue, Jun 9
Southwest Logo
7:00 am - 9:30 am
SDF
-
ECP
3h 30m
1 stop
Southwest Logo
7:00 am - 8:25 pm
ECP
-
SDF
12h 25m
2 stops
$344Southwest
Tue, Jun 2 - Tue, Jun 9
Delta Logo
7:30 pm - 10:47 pm
SDF
-
ECP
4h 17m
1 stop
Delta Logo
7:05 pm - 12:02 am
ECP
-
SDF
3h 57m
1 stop
$345Delta
Wed, Oct 7 - Mon, Oct 12
Southwest Logo
3:30 pm - 8:25 pm
SDF
-
ECP
5h 55m
2 stops
Southwest Logo
7:00 am - 8:25 pm
ECP
-
SDF
12h 25m
2 stops
$349Southwest
Tue, Jun 2 - Tue, Jun 9
Delta Logo
5:47 pm - 10:51 pm
SDF
-
ECP
6h 04m
1 stop
Delta Logo
7:41 am - 2:42 pm
ECP
-
SDF
6h 01m
1 stop
$351Delta
Sat, May 30 - Sat, Jun 6

Delta flights from Louisville to Panama City, Florida

Our best Delta deals on Louisville to Panama City, Florida flight tickets
Delta
Jun 16
SDF6:00 amLouisville Intl
5h 54m
1 stop
ECP10:54 amPanama City NW Florida Beaches
Jun 23
ECP5:08 pmPanama City NW Florida Beaches
6h 24m
1 stop
SDF12:32 amLouisville Intl
$319
Delta
Oct 7
SDF7:30 pmLouisville Intl
4h 17m
1 stop
ECP10:47 pmPanama City NW Florida Beaches
Oct 12
ECP7:05 pmPanama City NW Florida Beaches
3h 57m
1 stop
SDF12:02 amLouisville Intl
$345
Delta
May 30
SDF5:47 pmLouisville Intl
6h 04m
1 stop
ECP10:51 pmPanama City NW Florida Beaches
Jun 6
ECP7:41 amPanama City NW Florida Beaches
6h 01m
1 stop
SDF2:42 pmLouisville Intl
$351

Southwest flights from Louisville to Panama City, Florida

Our best Southwest deals on Louisville to Panama City, Florida flight tickets
Southwest
Jun 2
SDF4:40 pmLouisville Intl
3h 15m
1 stop
ECP6:55 pmPanama City NW Florida Beaches
Jun 9
ECP2:25 pmPanama City NW Florida Beaches
7h 45m
2 stops
SDF11:10 pmLouisville Intl
$324
Southwest
Jun 3
SDF3:30 pmLouisville Intl
5h 55m
2 stops
ECP8:25 pmPanama City NW Florida Beaches
Jun 10
ECP7:40 amPanama City NW Florida Beaches
11h 45m
2 stops
SDF8:25 pmLouisville Intl
$335
Southwest
Jun 2
SDF4:40 pmLouisville Intl
3h 15m
1 stop
ECP6:55 pmPanama City NW Florida Beaches
Jun 9
ECP5:25 pmPanama City NW Florida Beaches
3h 15m
1 stop
SDF9:40 pmLouisville Intl
$339

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Louisville to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Tue 6/16

6:00 am-10:54 am

1 stop5h 54m

Panama City NW Florida Beaches

Tue 6/23

5:08 pm-12:32 am

1 stop6h 24m

$319

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Tue 6/2

4:40 pm-6:55 pm

1 stop3h 15m

Panama City NW Florida Beaches

Tue 6/9

2:25 pm-11:10 pm

2 stops7h 45m

$324

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Tue 6/2

7:11 am-3:46 pm

2 stops9h 35m

Panama City NW Florida Beaches

Tue 6/9

11:00 am-9:41 pm

2 stops9h 41m

$329

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Wed 6/3

3:30 pm-8:25 pm

2 stops5h 55m

Panama City NW Florida Beaches

Wed 6/10

7:40 am-8:25 pm

2 stops11h 45m

$335
Quickest round-trip

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Tue 6/2

4:40 pm-6:55 pm

1 stop3h 15m

Panama City NW Florida Beaches

Tue 6/9

5:25 pm-9:40 pm

1 stop3h 15m

$339

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Thu 6/4

8:08 pm-11:40 pm

1 stop4h 32m

Panama City NW Florida Beaches

Tue 6/9

7:05 am-5:45 pm

2 stops9h 40m

$340

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Tue 6/2

7:00 am-9:30 am

1 stop3h 30m

Panama City NW Florida Beaches

Tue 6/9

7:00 am-8:25 pm

2 stops12h 25m

$344

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Wed 10/7

7:30 pm-10:47 pm

1 stop4h 17m

Panama City NW Florida Beaches

Mon 10/12

7:05 pm-12:02 am

1 stop3h 57m

$345

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Tue 6/2

3:30 pm-8:25 pm

2 stops5h 55m

Panama City NW Florida Beaches

Tue 6/9

7:00 am-8:25 pm

2 stops12h 25m

$349

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

Sat 5/30

5:47 pm-10:51 pm

1 stop6h 04m

Panama City NW Florida Beaches

Sat 6/6

7:41 am-2:42 pm

1 stop6h 01m

$351

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Louisville to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and Panama City, Florida?

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Louisville is in August. Flight prices, which tend to average around $289, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Panama City, Florida, with average flight prices from Louisville averaging around $291.

How far in advance should I book a flight from Louisville to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $381 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Louisville for as low as $301 on momondo.

How have Louisville to Panama City, Florida flight prices changed over time?

As of May 2026, prices for Louisville to Panama City, Florida flights are approximately 12% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Panama City, Florida (SDF to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama City, Florida

Fastest flight time

3h 15m

Direct flights

None
The fastest flight from Louisville to Panama City, Florida takes 3h 15m
There are no direct flights from Louisville to Panama City, Florida. There are no popular flight routes from Louisville to Panama City, Florida.
Search flight deals

Frequently asked questions about flying from Louisville to Panama City, Florida

  • How far is Louisville Intl to Panama City NW Florida Beaches by plane?

    A flight from Louisville Intl to Panama City NW Florida Beaches will travel around 558.6 mi. Typically, this will take 3h 15m by plane in normal conditions.

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The necessary travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Louisville to Panama City, Florida?

Best airlines flying from Louisville to Panama City, Florida

Compare and see reviews for airlines that fly from Louisville to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $236Free CancellationRating
7.9
8,458 reviews
Search Delta flights
American AirlinesPriceFrom $256Free CancellationRating
7.1
11,668 reviews
Search American Airlines flights
SouthwestPriceFrom $318Free CancellationRating
7.9
4,305 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Louisville to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Louisville to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to Panama City?

Once you have performed a search for Louisville to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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