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Cheap flights from Louisville to Panama City from $224

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama City departing on 1/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:45 pm - 10:51 pm
SDF
-
ECP
6h 06m1 stop
Delta Logo
3:45 pm - 8:56 pm
ECP
-
SDF
4h 11m1 stop
$288Delta
sáb., ene. 17 - lun., ene. 26
Delta Logo
5:45 pm - 10:51 pm
SDF
-
ECP
6h 06m1 stop
Delta Logo
6:00 am - 11:37 am
ECP
-
SDF
4h 37m1 stop
$311Delta
sáb., ene. 17 - lun., ene. 19
American Airlines Logo
6:00 am - 11:33 am
SDF
-
ECP
6h 33m1 stop
American Airlines Logo
12:03 pm - 11:19 pm
ECP
-
SDF
10h 16m2 stops
$316American Airlines
dom., ene. 18 - sáb., ene. 24
United Airlines Logo
9:15 am - 4:12 pm
SDF
-
ECP
7h 57m1 stop
United Airlines Logo
6:30 am - 1:14 pm
ECP
-
SDF
5h 44m1 stop
$318United Airlines
mar., ene. 13 - jue., ene. 15
Delta Logo
5:35 am - 8:39 am
SDF
-
ECP
4h 04m1 stop
Delta Logo
3:45 pm - 8:56 pm
ECP
-
SDF
4h 11m1 stop
$321Delta
lun., ene. 19 - jue., ene. 29
Southwest Logo
11:05 am - 6:10 pm
SDF
-
ECP
8h 05m2 stops
Southwest Logo
12:35 pm - 9:25 pm
ECP
-
SDF
7h 50m2 stops
$323Southwest
mar., ene. 13 - jue., ene. 15
American Airlines Logo
8:06 am - 5:33 pm
SDF
-
ECP
10h 27m2 stops
American Airlines Logo
1:40 pm - 10:05 pm
ECP
-
SDF
7h 25m1 stop
$326American Airlines
dom., ene. 11 - sáb., ene. 17
American Airlines Logo
8:06 am - 5:33 pm
SDF
-
ECP
10h 27m2 stops
American Airlines Logo
12:03 pm - 10:05 pm
ECP
-
SDF
9h 02m2 stops
$331American Airlines
dom., ene. 11 - sáb., ene. 17
Delta Logo
6:00 am - 9:12 am
SDF
-
ECP
4h 12m1 stop
Delta Logo
7:20 am - 2:36 pm
ECP
-
SDF
6h 16m1 stop
$344Delta
vie., ene. 16 - mar., ene. 27
Southwest Logo
11:50 am - 6:10 pm
SDF
-
ECP
7h 20m1 stop
Southwest Logo
12:35 pm - 9:25 pm
ECP
-
SDF
7h 50m2 stops
$346Southwest
mar., ene. 20 - dom., ene. 25

United Airlines flights from Louisville to Panama City, Florida

Our best United Airlines deals on Louisville to Panama City, Florida flight tickets
United Airlines
Jan 15
SDF6:00 amLouisville Intl
7h 02m
1 stop
ECP12:02 pmPanama City NW Florida Beaches
Jan 21
ECP1:10 pmPanama City NW Florida Beaches
7h 49m
1 stop
SDF9:59 pmLouisville Intl
$298
Find similar
United Airlines
Jan 13
SDF9:15 amLouisville Intl
7h 57m
1 stop
ECP4:12 pmPanama City NW Florida Beaches
Jan 15
ECP6:30 amPanama City NW Florida Beaches
5h 44m
1 stop
SDF1:14 pmLouisville Intl
$318
Find similar
United Airlines
Jan 20
SDF9:15 amLouisville Intl
7h 57m
1 stop
ECP4:12 pmPanama City NW Florida Beaches
Jan 21
ECP6:30 amPanama City NW Florida Beaches
10h 07m
2 stops
SDF5:37 pmLouisville Intl
$349
Find similar

Southwest flights from Louisville to Panama City, Florida

Our best Southwest deals on Louisville to Panama City, Florida flight tickets
Southwest
Feb 3
SDF11:05 amLouisville Intl
8h 05m
2 stops
ECP6:10 pmPanama City NW Florida Beaches
Feb 24
ECP10:30 amPanama City NW Florida Beaches
10h 40m
2 stops
SDF10:10 pmLouisville Intl
$303
Find similar
Southwest
Jan 13
SDF11:05 amLouisville Intl
8h 05m
2 stops
ECP6:10 pmPanama City NW Florida Beaches
Jan 15
ECP12:35 pmPanama City NW Florida Beaches
7h 50m
2 stops
SDF9:25 pmLouisville Intl
$323
Find similar
Southwest
Jan 20
SDF11:50 amLouisville Intl
7h 20m
1 stop
ECP6:10 pmPanama City NW Florida Beaches
Jan 25
ECP12:35 pmPanama City NW Florida Beaches
7h 50m
2 stops
SDF9:25 pmLouisville Intl
$346
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 16, 2025.
Use the filters below to find and compare flights from Louisville to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

sáb. 1/17

5:45 pm-10:51 pm

1 stop6h 06m

Panama City NW Florida Beaches

lun. 1/26

3:45 pm-8:56 pm

1 stop4h 11m

$288

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

sáb. 1/17

5:45 pm-10:51 pm

1 stop6h 06m

Panama City NW Florida Beaches

lun. 1/19

6:00 am-11:37 am

1 stop4h 37m

$311

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

dom. 1/18

6:00 am-11:33 am

1 stop6h 33m

Panama City NW Florida Beaches

sáb. 1/24

12:03 pm-11:19 pm

2 stops10h 16m

$316

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

mar. 1/13

9:15 am-4:12 pm

1 stop7h 57m

Panama City NW Florida Beaches

jue. 1/15

6:30 am-1:14 pm

1 stop5h 44m

$318

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

lun. 1/19

5:35 am-8:39 am

1 stop4h 04m

Panama City NW Florida Beaches

jue. 1/29

3:45 pm-8:56 pm

1 stop4h 11m

$321

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

mar. 1/13

11:05 am-6:10 pm

2 stops8h 05m

Panama City NW Florida Beaches

jue. 1/15

12:35 pm-9:25 pm

2 stops7h 50m

$323

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

dom. 1/11

8:06 am-5:33 pm

2 stops10h 27m

Panama City NW Florida Beaches

sáb. 1/17

1:40 pm-10:05 pm

1 stop7h 25m

$326

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

dom. 1/11

8:06 am-5:33 pm

2 stops10h 27m

Panama City NW Florida Beaches

sáb. 1/17

12:03 pm-10:05 pm

2 stops9h 02m

$331

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

vie. 1/16

6:00 am-9:12 am

1 stop4h 12m

Panama City NW Florida Beaches

mar. 1/27

7:20 am-2:36 pm

1 stop6h 16m

$344

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

mar. 1/20

11:50 am-6:10 pm

1 stop7h 20m

Panama City NW Florida Beaches

dom. 1/25

12:35 pm-9:25 pm

2 stops7h 50m

$346

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Louisville to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Louisville is in August. Flight prices, which tend to average around $288, are often lower during this time because this is during the off-season. The month of October is another great option to travel to Panama City, Florida, with average flight prices from Louisville averaging around $310.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Wednesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $336. On the other hand, Tuesday is the most expensive day to depart from Louisville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $375.

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $364 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Louisville for as low as $284 on momondo.

How have Louisville to Panama City, Florida flight prices changed over time?

As of December 2025, prices for Louisville to Panama City, Florida flights are approximately 223% more expensive when compared to flights at the same time last year.

When to book flights from Louisville to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Panama City, Florida (SDF to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama City, Florida

Fastest flight time

3h 39m

Direct flights

None
The fastest flight from Louisville to Panama City, Florida takes 3h 39m
There are no direct flights from Louisville to Panama City, Florida. There are no popular flight routes from Louisville to Panama City, Florida.
Search flight deals

  • How far is Louisville Intl to Panama City NW Florida Beaches by plane?

    A flight from Louisville Intl to Panama City NW Florida Beaches will travel around 558.6 mi. Typically, this will take 3h 39m by plane in normal conditions.

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The necessary travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Louisville to Panama City, Florida?

Best airlines flying from Louisville to Panama City, Florida

Compare and see reviews for airlines that fly from Louisville to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $236Free CancellationRating
7.9
8,008 reviews
Search Delta flights
American AirlinesPriceFrom $256Free CancellationRating
7.2
11,049 reviews
Search American Airlines flights
SouthwestPriceFrom $338Free CancellationRating
7.9
4,250 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Louisville to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Louisville to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to Panama City?

Once you have performed a search for Louisville to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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