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Cheap flights from Louisville to Panama City from $114

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama City departing on 9/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Louisville to Panama City (SDF-ECP)

Cheap round-trip flights

Delta Logo
6:00 pm - 11:06 pmSDF-ECP
6h 06m1 stop
Delta Logo
4:46 pm - 10:46 pmECP-SDF
5h 00m1 stop
$227Delta
Find Deal
sáb., sep. 6 - jue., sep. 11
American Airlines Logo
10:50 am - 5:30 pmSDF-ECP
7h 40m2 stops
American Airlines Logo
5:30 am - 11:42 amECP-SDF
5h 12m1 stop
$232American Airlines
Find Deal
lun., ago. 25 - sáb., ago. 30
Delta Logo
7:10 am - 9:55 amSDF-ECP
3h 45m1 stop
Delta Logo
4:46 pm - 9:13 pmECP-SDF
3h 27m1 stop
$239Delta
Find Deal
dom., sep. 21 - lun., sep. 29
Delta Logo
7:10 am - 9:55 amSDF-ECP
3h 45m1 stop
Delta Logo
6:00 am - 10:00 amECP-SDF
3h 00m1 stop
$242Delta
Find Deal
vie., sep. 19 - mar., sep. 23
Delta Logo
6:00 am - 8:12 amSDF-ECP
3h 12m1 stop
Delta Logo
4:46 pm - 9:13 pmECP-SDF
3h 27m1 stop
$251Delta
Find Deal
dom., sep. 7 - vie., sep. 12
American Airlines Logo
10:49 am - 6:14 pmSDF-ECP
8h 25m2 stops
American Airlines Logo
6:32 am - 1:54 pmECP-SDF
6h 22m1 stop
$262American Airlines
Find Deal
dom., ago. 31 - sáb., sep. 6
United Airlines Logo
9:40 am - 2:24 pmSDF-ECP
5h 44m1 stop
United Airlines Logo
6:30 am - 10:57 pmECP-SDF
15h 27m2 stops
$302United Airlines
Find Deal
lun., sep. 8 - mar., sep. 9
Southwest Logo
11:50 am - 9:00 pmSDF-ECP
10h 10m1 stop
Southwest Logo
2:55 pm - 11:40 pmECP-SDF
7h 45m2 stops
$308Southwest
Find Deal
lun., sep. 29 - vie., oct. 3
Southwest Logo
11:50 am - 9:25 pmSDF-ECP
10h 35m2 stops
Southwest Logo
7:40 am - 3:15 pmECP-SDF
6h 35m1 stop
$314Southwest
Find Deal
jue., sep. 11 - mar., sep. 16
United Airlines Logo
9:40 am - 4:20 pmSDF-ECP
7h 40m1 stop
United Airlines Logo
6:30 am - 10:57 pmECP-SDF
15h 27m2 stops
$332United Airlines
Find Deal
vie., sep. 5 - mar., sep. 9

Delta flights from Louisville to Panama City, Florida

Our best Delta deals on Louisville to Panama City, Florida flight tickets
Delta
Sep 6
SDF6:00 pmLouisville Intl
6h 06m
1 stop
ECP11:06 pmPanama City NW Florida Beaches
Sep 11
ECP4:46 pmPanama City NW Florida Beaches
5h 00m
1 stop
SDF10:46 pmLouisville Intl
$227
Find similar
Delta
Sep 21
SDF7:10 amLouisville Intl
3h 45m
1 stop
ECP9:55 amPanama City NW Florida Beaches
Sep 29
ECP4:46 pmPanama City NW Florida Beaches
3h 27m
1 stop
SDF9:13 pmLouisville Intl
$239
Find similar
Delta
Sep 19
SDF7:10 amLouisville Intl
3h 45m
1 stop
ECP9:55 amPanama City NW Florida Beaches
Sep 23
ECP6:00 amPanama City NW Florida Beaches
3h 00m
1 stop
SDF10:00 amLouisville Intl
$242
Find similar

American Airlines flights from Louisville to Panama City, Florida

Our best American Airlines deals on Louisville to Panama City, Florida flight tickets
American Airlines
Aug 25
SDF10:50 amLouisville Intl
7h 40m
2 stops
ECP5:30 pmPanama City NW Florida Beaches
Aug 30
ECP5:30 amPanama City NW Florida Beaches
5h 12m
1 stop
SDF11:42 amLouisville Intl
$232
Find similar
American Airlines
Aug 31
SDF10:49 amLouisville Intl
8h 25m
2 stops
ECP6:14 pmPanama City NW Florida Beaches
Sep 6
ECP6:32 amPanama City NW Florida Beaches
6h 22m
1 stop
SDF1:54 pmLouisville Intl
$262
Find similar
American Airlines
Sep 11
SDF12:08 pmLouisville Intl
7h 21m
1 stop
ECP6:29 pmPanama City NW Florida Beaches
Sep 16
ECP3:53 pmPanama City NW Florida Beaches
6h 47m
1 stop
SDF11:40 pmLouisville Intl
$287
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated agosto 7, 2025.
Use the filters below to find and compare flights from Louisville to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

sáb. 9/6

6:00 pm-11:06 pm

1 stop6h 06m

Panama City NW Florida Beaches

jue. 9/11

4:46 pm-10:46 pm

1 stop5h 00m

$227

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

lun. 8/25

10:50 am-5:30 pm

2 stops7h 40m

Panama City NW Florida Beaches

sáb. 8/30

5:30 am-11:42 am

1 stop5h 12m

$232

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

dom. 9/21

7:10 am-9:55 am

1 stop3h 45m

Panama City NW Florida Beaches

lun. 9/29

4:46 pm-9:13 pm

1 stop3h 27m

$239

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

vie. 9/19

7:10 am-9:55 am

1 stop3h 45m

Panama City NW Florida Beaches

mar. 9/23

6:00 am-10:00 am

1 stop3h 00m

$242

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

dom. 9/7

6:00 am-8:12 am

1 stop3h 12m

Panama City NW Florida Beaches

vie. 9/12

4:46 pm-9:13 pm

1 stop3h 27m

$251

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

dom. 8/31

10:49 am-6:14 pm

2 stops8h 25m

Panama City NW Florida Beaches

sáb. 9/6

6:32 am-1:54 pm

1 stop6h 22m

$262

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

lun. 9/8

9:40 am-2:24 pm

1 stop5h 44m

Panama City NW Florida Beaches

mar. 9/9

6:30 am-10:57 pm

2 stops15h 27m

$302

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

lun. 9/29

11:50 am-9:00 pm

1 stop10h 10m

Panama City NW Florida Beaches

vie. 10/3

2:55 pm-11:40 pm

2 stops7h 45m

$308

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

jue. 9/11

11:50 am-9:25 pm

2 stops10h 35m

Panama City NW Florida Beaches

mar. 9/16

7:40 am-3:15 pm

1 stop6h 35m

$314

LouisvillePanama City

SDF - ECP

SDFECP

Louisville Intl

vie. 9/5

9:40 am-4:20 pm

1 stop7h 40m

Panama City NW Florida Beaches

mar. 9/9

6:30 am-10:57 pm

2 stops15h 27m

$332

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Louisville to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Louisville is in August. Flight prices, which tend to average around $298, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Panama City, Florida, with average flight prices from Louisville averaging around $322.

What is the cheapest day to depart on your flight to Panama City, Florida?

Our data shows that Wednesday is the least expensive day to fly to Panama City, Florida. Tickets to fly out on this day can be as low as $336. On the other hand, Tuesday is the most expensive day to depart from Louisville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $375.

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $370 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from Louisville for as low as $294 on momondo.

How have Louisville to Panama City, Florida flight prices changed over time?

As of August 2025, prices for Louisville to Panama City, Florida flights are approximately 37% cheaper when compared to flights at the same time last year.

When to book flights from Louisville to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Panama City, Florida (SDF to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama City, Florida

Best Price Found

$114

Fastest flight time

3h 12m

Direct flights

None

Airports in Panama City, Florida

1 airport
The best one-way flight to Panama City, Florida from Louisville in the past 72 hours is $114. The best round-trip flight deal from Louisville to Panama City, Florida found on momondo in the last 72 hours is $227.
The fastest flight from Louisville to Panama City, Florida takes 3h 12m
There are no direct flights from Louisville to Panama City, Florida. Popular non-direct route for this connection is Louisville Intl Airport - Panama City NW Florida Beaches Airport.
There is 1 airport near Panama City, Florida: Panama City NW Florida Beaches (ECP)
Search flight deals

  • How far is Louisville Intl to Panama City NW Florida Beaches by plane?

    A flight from Louisville Intl to Panama City NW Florida Beaches will travel around 558.6 mi. Typically, this will take 3h 12m by plane in normal conditions.

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The necessary travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Louisville to Panama City, Florida?

Best airlines flying from Louisville to Panama City, Florida

Compare and see reviews for airlines that fly from Louisville to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $235Free CancellationRating
8.0
7,985 reviews
Search Delta flights
American AirlinesPriceFrom $256Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $338Free CancellationRating
8.0
4,247 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Louisville to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Louisville to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to Panama City?

Once you have performed a search for Louisville to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Louisville to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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