Cheap flights from Louisville to Iowa from $146

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Iowa departing on 4/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Louisville to Iowa

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
10:39 am - 4:48 pm
SDF
-
DSM
7h 09m
1 stop
Delta Logo
6:15 am - 1:51 pm
DSM
-
SDF
6h 36m
1 stop
$287Delta
Tue, May 19 - Tue, May 26
Southwest Logo
8:55 am - 11:25 am
SDF
-
DSM
3h 30m
1 stop
Southwest Logo
3:15 pm - 8:35 pm
DSM
-
SDF
4h 20m
1 stop
$291Southwest
Tue, Apr 21 - Wed, Apr 22
Southwest Logo
8:55 am - 11:25 am
SDF
-
DSM
3h 30m
1 stop
Southwest Logo
5:30 am - 5:10 pm
DSM
-
SDF
10h 40m
2 stops
$296Southwest
Tue, Apr 21 - Wed, Apr 22
Multiple Airlines Logo
11:16 am - 10:42 pm
SDF
-
DSM
12h 26m
2 stops
Multiple Airlines Logo
8:30 am - 5:04 pm
DSM
-
SDF
7h 34m
1 stop
$297Multiple Airlines
Fri, Apr 24 - Sun, Apr 26
Delta Logo
2:34 pm - 8:36 pm
SDF
-
DSM
7h 02m
1 stop
Delta Logo
4:00 pm - 11:59 pm
DSM
-
SDF
6h 59m
1 stop
$299Delta
Tue, Jun 2 - Sat, Jun 6
United Airlines Logo
5:00 am - 9:58 am
SDF
-
MLI
5h 58m
1 stop
United Airlines Logo
7:34 pm - 11:59 pm
MLI
-
SDF
3h 25m
1 stop
$309United Airlines
Sat, Apr 25 - Mon, Apr 27
American Airlines Logo
7:01 pm - 10:14 pm
SDF
-
CID
4h 13m
1 stop
American Airlines Logo
6:35 am - 1:50 pm
CID
-
SDF
6h 15m
1 stop
$309American Airlines
Thu, Apr 30 - Sun, May 3
American Airlines Logo
6:31 am - 12:21 pm
SDF
-
MLI
6h 50m
2 stops
American Airlines Logo
3:48 pm - 11:11 pm
MLI
-
SDF
6h 23m
1 stop
$314American Airlines
Sat, Apr 25 - Mon, Apr 27
United Airlines Logo
9:07 am - 12:27 pm
SDF
-
MLI
4h 20m
1 stop
United Airlines Logo
7:34 pm - 11:59 pm
MLI
-
SDF
3h 25m
1 stop
$319United Airlines
Thu, Apr 16 - Mon, Apr 20
Multiple Airlines Logo
11:16 am - 10:42 pm
SDF
-
DSM
12h 26m
2 stops
Multiple Airlines Logo
8:30 am - 5:04 pm
DSM
-
SDF
7h 34m
1 stop
$328Multiple Airlines
Fri, Apr 24 - Sun, Apr 26

United Airlines flights from Louisville to Iowa

Our best United Airlines deals on Louisville to Iowa flight tickets
United Airlines
Apr 25
SDF5:00 amLouisville Intl
5h 58m
1 stop
MLI9:58 amMoline Quad-City
Apr 27
MLI7:34 pmMoline Quad-City
3h 25m
1 stop
SDF11:59 pmLouisville Intl
$309
United Airlines
Apr 16
SDF9:07 amLouisville Intl
4h 20m
1 stop
MLI12:27 pmMoline Quad-City
Apr 20
MLI7:34 pmMoline Quad-City
3h 25m
1 stop
SDF11:59 pmLouisville Intl
$319
United Airlines
May 1
SDF3:37 pmLouisville Intl
5h 52m
1 stop
OMA8:29 pmOmaha Eppley Airfield
May 2
OMA8:01 amOmaha Eppley Airfield
5h 06m
1 stop
SDF2:07 pmLouisville Intl
$327

Southwest flights from Louisville to Iowa

Our best Southwest deals on Louisville to Iowa flight tickets
Southwest
Apr 21
SDF8:55 amLouisville Intl
3h 30m
1 stop
DSM11:25 amDes Moines
Apr 22
DSM3:15 pmDes Moines
4h 20m
1 stop
SDF8:35 pmLouisville Intl
$291
Southwest
Apr 21
SDF8:55 amLouisville Intl
3h 30m
1 stop
DSM11:25 amDes Moines
Apr 22
DSM5:30 amDes Moines
10h 40m
2 stops
SDF5:10 pmLouisville Intl
$296
Southwest
Apr 20
SDF8:10 pmLouisville Intl
3h 55m
1 stop
DSM11:05 pmDes Moines
Apr 21
DSM6:55 amDes Moines
7h 55m
1 stop
SDF3:50 pmLouisville Intl
$301

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from Louisville to Iowa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Tue 5/19

10:39 am-4:48 pm

1 stop7h 09m

Des Moines

Tue 5/26

6:15 am-1:51 pm

1 stop6h 36m

$287

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Tue 4/21

8:55 am-11:25 am

1 stop3h 30m

Des Moines

Wed 4/22

3:15 pm-8:35 pm

1 stop4h 20m

$291

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Tue 4/21

8:55 am-11:25 am

1 stop3h 30m

Des Moines

Wed 4/22

5:30 am-5:10 pm

2 stops10h 40m

$296

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Fri 4/24

11:16 am-10:42 pm

2 stops12h 26m

Des Moines

Sun 4/26

8:30 am-5:04 pm

1 stop7h 34m

$297

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Tue 6/2

2:34 pm-8:36 pm

1 stop7h 02m

Des Moines

Sat 6/6

4:00 pm-11:59 pm

1 stop6h 59m

$299

LouisvilleMoline

SDF - MLI

SDFMLI

Louisville Intl

Sat 4/25

5:00 am-9:58 am

1 stop5h 58m

Moline Quad-City

Mon 4/27

7:34 pm-11:59 pm

1 stop3h 25m

$309

LouisvilleCedar Rapids

SDF - CID

SDFCID

Louisville Intl

Thu 4/30

7:01 pm-10:14 pm

1 stop4h 13m

Cedar Rapids

Sun 5/3

6:35 am-1:50 pm

1 stop6h 15m

$309

LouisvilleMoline

SDF - MLI

SDFMLI

Louisville Intl

Sat 4/25

6:31 am-12:21 pm

2 stops6h 50m

Moline Quad-City

Mon 4/27

3:48 pm-11:11 pm

1 stop6h 23m

$314
Quickest round-trip

LouisvilleMoline

SDF - MLI

SDFMLI

Louisville Intl

Thu 4/16

9:07 am-12:27 pm

1 stop4h 20m

Moline Quad-City

Mon 4/20

7:34 pm-11:59 pm

1 stop3h 25m

$319

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Fri 4/24

11:16 am-10:42 pm

2 stops12h 26m

Des Moines

Sun 4/26

8:30 am-5:04 pm

1 stop7h 34m

$328

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Iowa from

How to get the cheapest flight ticket from Louisville to Iowa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Louisville Intl to Iowa?

Southwest, American Airlines, and Delta are the most popular carriers operating from Louisville Intl to Iowa

What airlines fly to Iowa?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Iowa from Louisville according to our data. American Airlines is the first choice among our users, with 38% of people opting to fly with this airline when traveling to Iowa. Keep in mind that there are 3 different airlines that fly to Iowa on a routine basis, so you have a few additional options to choose from.

Cheap Louisville to Iowa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Iowa

Fastest flight time

3h 55m

Direct flights

None
The fastest flight from Louisville to Iowa takes 3h 55m
There are no direct flights from Louisville to Iowa. There are no popular flight routes from Louisville to Iowa.

Frequently asked questions about flying from Louisville to Iowa

  • When did momondo last update prices for flights from Louisville Intl Airport to Iowa?

    Prices for flights from Louisville Intl Airport to Iowa refresh daily.

  • How many operators does momondo search for flights from Louisville Intl Airport to Iowa?

  • How old do you have to be to fly from Louisville Intl Airport to Iowa?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Iowa.

  • What documentation or ID do you need to fly to Iowa?

    The travel and health documents you'll need for your trip to Iowa may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Iowa. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Louisville to Iowa

Compare and see reviews for airlines that fly from Louisville to Iowa with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $105Free CancellationRating
7.9
8,374 reviews
Search Delta flights
American AirlinesPriceFrom $158Free CancellationRating
7.1
11,551 reviews
Search American Airlines flights
United AirlinesPriceFrom $248Free CancellationRating
7.4
9,538 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Iowa?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Louisville to Iowa. momondo saves you time and could save you money on your trip.

Can I find flights from Louisville to Iowa with flexible booking policies on momondo?

Yes. All flights to Iowa from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to Iowa?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Iowa.

I’m not ready to book a flight from Louisville to Iowa right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Iowa, momondo offers a useful price alert feature which will track prices for flights to Iowa from Louisville and alert you when they change.

An easier way to manage your Iowa trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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1 adult
Sun 5/3
Sun 5/10

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