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Cheap flights from Knoxville to St. Louis from $175

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to St. Louis departing on 6/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Easily compare round-trip flights from Knoxville to St. Louis

Below you can see the best fares for your round-trip flight route over the next six months. All fares were found on momondo this week. Browse the quickest and cheapest flights from Knoxville to St. Louis by changing tabs
Delta
Aug 8
TYS5:35 amKnoxville McGhee Tyson
4h 17m
1 stop
STL8:52 amLambert-St Louis
Aug 11
STL7:15 pmLambert-St Louis
3h 42m
1 stop
TYS11:57 pmKnoxville McGhee Tyson
American Airlines
Jun 10
TYS5:05 pmKnoxville McGhee Tyson
5h 23m
1 stop
STL9:28 pmLambert-St Louis
Jun 11
STL5:38 pmLambert-St Louis
5h 20m
1 stop
TYS11:58 pmKnoxville McGhee Tyson
Delta
May 11
TYS2:53 pmKnoxville McGhee Tyson
4h 48m
1 stop
STL6:41 pmLambert-St Louis
May 14
STL6:00 amLambert-St Louis
3h 11m
1 stop
TYS10:11 amKnoxville McGhee Tyson
United Airlines
May 24
TYS3:00 pmKnoxville McGhee Tyson
25h 41m
1 stop
STL3:41 pmLambert-St Louis
May 31
STL11:38 amLambert-St Louis
11h 06m
2 stops
TYS11:44 pmKnoxville McGhee Tyson
American Airlines
Aug 8
TYS7:11 amKnoxville McGhee Tyson
3h 53m
1 stop
STL10:04 amLambert-St Louis
Aug 11
STL6:26 amLambert-St Louis
6h 45m
2 stops
TYS2:11 pmKnoxville McGhee Tyson
American Airlines
May 24
TYS5:58 pmKnoxville McGhee Tyson
6h 24m
1 stop
STL11:22 pmLambert-St Louis
May 31
STL5:04 amLambert-St Louis
4h 33m
1 stop
TYS10:37 amKnoxville McGhee Tyson

Find the cheapest one-way flights from Knoxville to St. Louis

If you're looking for one-way flights from Knoxville to St. Louis, view some of our deals below provided by American Airlines, Delta and Frontier
Frontier
Jun 7
TYS10:25 pmKnoxville McGhee Tyson
12h 05m
1 stop
STL9:30 amLambert-St Louis
United Airlines
May 15
TYS4:10 pmKnoxville McGhee Tyson
23h 13m
2 stops
STL2:23 pmLambert-St Louis
American Airlines
May 13
TYS7:01 amKnoxville McGhee Tyson
3h 52m
1 stop
STL9:53 amLambert-St Louis

Search last-minute flights to St. Louis from Knoxville

Find and compare round-trip flight prices for your last-minute flight from Knoxville to St. Louis
Delta
May 11
TYS2:53 pmKnoxville McGhee Tyson
4h 48m
1 stop
STL6:41 pmLambert-St Louis
May 14
STL6:00 amLambert-St Louis
3h 11m
1 stop
TYS10:11 amKnoxville McGhee Tyson
American Airlines
May 3
TYS5:15 pmKnoxville McGhee Tyson
5h 00m
1 stop
STL9:15 pmLambert-St Louis
May 4
STL4:42 pmLambert-St Louis
4h 05m
1 stop
TYS9:47 pmKnoxville McGhee Tyson
United Airlines
May 3
TYS7:00 amKnoxville McGhee Tyson
15h 09m
2 stops
STL9:09 pmLambert-St Louis
May 4
STL8:05 amLambert-St Louis
4h 17m
1 stop
TYS1:22 pmKnoxville McGhee Tyson
American Airlines
May 6
TYS5:19 amKnoxville McGhee Tyson
5h 34m
1 stop
STL9:53 amLambert-St Louis
May 9
STL5:04 amLambert-St Louis
6h 04m
1 stop
TYS12:08 pmKnoxville McGhee Tyson
United Airlines
May 6
TYS10:51 amKnoxville McGhee Tyson
5h 55m
1 stop
STL3:46 pmLambert-St Louis
May 9
STL10:10 amLambert-St Louis
8h 54m
2 stops
TYS8:04 pmKnoxville McGhee Tyson
United Airlines
May 6
TYS2:25 pmKnoxville McGhee Tyson
8h 30m
2 stops
STL9:55 pmLambert-St Louis
May 9
STL10:10 amLambert-St Louis
8h 54m
2 stops
TYS8:04 pmKnoxville McGhee Tyson

Best airlines flying from Knoxville to St. Louis

Compare and see reviews for airlines that fly from Knoxville to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $206Free CancellationRating
7.3
14,875 reviews
Search American Airlines flights
DeltaPriceFrom $228Free CancellationRating
8.0
10,951 reviews
Search Delta flights

American Airlines flights from Knoxville to St. Louis

Our best American Airlines deals on Knoxville to St. Louis flight tickets
American Airlines
May 3
TYS5:15 pmKnoxville McGhee Tyson
5h 00m
1 stop
STL9:15 pmLambert-St Louis
May 4
STL4:42 pmLambert-St Louis
4h 05m
1 stop
TYS9:47 pmKnoxville McGhee Tyson
American Airlines
Jun 10
TYS5:05 pmKnoxville McGhee Tyson
5h 23m
1 stop
STL9:28 pmLambert-St Louis
Jun 11
STL5:38 pmLambert-St Louis
5h 20m
1 stop
TYS11:58 pmKnoxville McGhee Tyson
American Airlines
Aug 8
TYS7:11 amKnoxville McGhee Tyson
3h 53m
1 stop
STL10:04 amLambert-St Louis
Aug 11
STL6:26 amLambert-St Louis
6h 45m
2 stops
TYS2:11 pmKnoxville McGhee Tyson

Delta flights from Knoxville to St. Louis

Our best Delta deals on Knoxville to St. Louis flight tickets
Delta
Aug 8
TYS5:35 amKnoxville McGhee Tyson
4h 17m
1 stop
STL8:52 amLambert-St Louis
Aug 11
STL7:15 pmLambert-St Louis
3h 42m
1 stop
TYS11:57 pmKnoxville McGhee Tyson
Delta
May 11
TYS2:53 pmKnoxville McGhee Tyson
4h 48m
1 stop
STL6:41 pmLambert-St Louis
May 14
STL6:00 amLambert-St Louis
3h 11m
1 stop
TYS10:11 amKnoxville McGhee Tyson

How to get the cheapest flight ticket from Knoxville to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly from Knoxville to St. Louis?

November. The cheapest time of year to fly to St. Louis from Knoxville is November. Most expensive is June

What is the cheapest day to depart Knoxville for St. Louis?

Wednesday. The cheapest day of the week is typically Wednesday. The most expensive is typically Monday

When is the cheapest time to fly from Knoxville to St. Louis?

At noon. Knoxville to St. Louis flights are approximately 35% more expensive in the morning than at noon

What is the cheapest airline that flies to St. Louis from Knoxville?

American Airlines. American Airlines and Delta are the most popular carriers operating from Knoxville to St. Louis

What is the cheapest Knoxville to St. Louis flight route?

Knoxville McGhee Tyson - Lambert-St Louis. Fly from Knoxville McGhee Tyson to Lambert-St Louis for the best Knoxville - St. Louis flight prices

How far in advance should you book Knoxville to St. Louis flights?

27 days before. The cheapest time to buy a flight from Knoxville to St. Louis is approximately 27 days to departure

Cheap Knoxville to St. Louis (TYS to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to St. Louis

Best Price Found

$175

Fastest flight time

3h 52m

Direct flights

None

Airports in St. Louis

1 airport
The best one-way flight to St. Louis from Knoxville in the past 72 hours is $175. The best round-trip flight deal from Knoxville to St. Louis found on momondo in the last 72 hours is $228.
The fastest flight from Knoxville to St. Louis takes 3h 52m
There are no direct flights from Knoxville to St. Louis. Popular non-direct route for this connection is Knoxville McGhee Tyson Airport - Lambert-St Louis Airport.
There is 1 airport near St. Louis: Lambert-St Louis (STL)

  • How far is Knoxville McGhee Tyson to Lambert-St Louis by plane?

    Lambert-St Louis is 390.7 mi away from Knoxville McGhee Tyson. By plane, this route typically takes 3h 53m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Lambert-St Louis Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Lambert-St Louis Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Lambert-St Louis Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.


Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to St. Louis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to St. Louis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to St. Louis with flexible booking policies on momondo?

Yes. All flights to St. Louis from Knoxville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Knoxville to St. Louis?

momondo provides multiple filters to help you find the best flight to St. Louis from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to St. Louis right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to St. Louis now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to St. Louis and let you know when they change.


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