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Cheap flights from Knoxville to Missouri from $117

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Missouri departing on 9/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Missouri

Cheap round-trip flights

Logo
1:22 pm - 10:53 pmTYS-MCI
10h 31m1 stop
Logo
6:00 am - 3:02 pmMCI-TYS
8h 02m1 stop
$212
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Fri, Aug 22 - Sun, Aug 24
Frontier Logo
8:40 pm - 9:06 amTYS-STL
13h 26m1 stop
Frontier Logo
7:55 pm - 7:45 pmSTL-TYS
22h 50m1 stop
$225Frontier
Find Deal
Thu, Sep 25 - Sun, Sep 28
Delta Logo
10:24 am - 4:05 pmTYS-STL
6h 41m1 stop
Delta Logo
6:01 am - 10:56 amSTL-TYS
3h 55m1 stop
$229Delta
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Thu, Sep 18 - Sun, Sep 21
American Airlines Logo
10:10 am - 1:51 pmTYS-STL
4h 41m1 stop
American Airlines Logo
5:15 am - 11:30 amSTL-TYS
5h 15m1 stop
$239American Airlines
Find Deal
Wed, Aug 13 - Sat, Aug 16
American Airlines Logo
5:20 pm - 9:10 pmTYS-STL
4h 50m1 stop
American Airlines Logo
7:23 am - 2:43 pmSTL-TYS
6h 20m1 stop
$249American Airlines
Find Deal
Fri, Sep 19 - Sun, Sep 21
Delta Logo
1:53 pm - 6:56 pmTYS-MCI
6h 03m1 stop
Delta Logo
5:45 am - 10:25 amMCI-TYS
3h 40m1 stop
$249Delta
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Wed, Sep 10 - Sat, Sep 13
United Airlines Logo
5:45 am - 2:39 pmTYS-SGF
9h 54m2 stops
United Airlines Logo
9:05 am - 6:09 pmSGF-TYS
8h 04m1 stop
$299United Airlines
Find Deal
Thu, Nov 27 - Sat, Dec 6
United Airlines Logo
4:40 pm - 11:30 pmTYS-MCI
7h 50m1 stop
United Airlines Logo
3:23 pm - 10:50 pmMCI-TYS
6h 27m1 stop
$319United Airlines
Find Deal
Fri, Sep 26 - Tue, Sep 30
Allegiant Air Logo
7:44 pm - 8:58 amTYS-SGF
14h 14m1 stop
Allegiant Air Logo
8:21 pm - 1:11 pmSGF-TYS
15h 50m1 stop
$419Allegiant Air
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Sun, Aug 10 - Mon, Aug 11
Allegiant Air Logo
6:58 pm - 8:48 amTYS-SGF
14h 50m1 stop
Allegiant Air Logo
8:21 pm - 10:14 amSGF-TYS
12h 53m1 stop
$470Allegiant Air
Find Deal
Sun, Nov 16 - Thu, Nov 20

Delta flights from Knoxville to Missouri

Our best Delta deals on Knoxville to Missouri flight tickets
Delta
Sep 18
TYS10:24 amKnoxville McGhee Tyson
6h 41m
1 stop
STL4:05 pmLambert-St Louis
Sep 21
STL6:01 amLambert-St Louis
3h 55m
1 stop
TYS10:56 amKnoxville McGhee Tyson
$229
Find similar
Delta
Sep 10
TYS1:53 pmKnoxville McGhee Tyson
6h 03m
1 stop
MCI6:56 pmKansas City
Sep 13
MCI5:45 amKansas City
3h 40m
1 stop
TYS10:25 amKnoxville McGhee Tyson
$249
Find similar
Delta
Dec 4
TYS5:30 amKnoxville McGhee Tyson
3h 39m
1 stop
STL8:09 amLambert-St Louis
Dec 7
STL6:00 amLambert-St Louis
4h 05m
1 stop
TYS11:05 amKnoxville McGhee Tyson
$254
Find similar

American Airlines flights from Knoxville to Missouri

Our best American Airlines deals on Knoxville to Missouri flight tickets
American Airlines
Aug 13
TYS10:10 amKnoxville McGhee Tyson
4h 41m
1 stop
STL1:51 pmLambert-St Louis
Aug 16
STL5:15 amLambert-St Louis
5h 15m
1 stop
TYS11:30 amKnoxville McGhee Tyson
$239
Find similar
American Airlines
Sep 19
TYS5:20 pmKnoxville McGhee Tyson
4h 50m
1 stop
STL9:10 pmLambert-St Louis
Sep 21
STL7:23 amLambert-St Louis
6h 20m
1 stop
TYS2:43 pmKnoxville McGhee Tyson
$249
Find similar
American Airlines
Aug 6
TYS12:20 pmKnoxville McGhee Tyson
7h 10m
1 stop
STL6:30 pmLambert-St Louis
Aug 15
STL5:15 amLambert-St Louis
7h 23m
1 stop
TYS1:38 pmKnoxville McGhee Tyson
$254
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Knoxville to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleKansas City

TYS - MCI

TYSMCI

Knoxville McGhee Tyson

Fri 8/22

1:22 pm-10:53 pm

1 stop10h 31m

Kansas City

Sun 8/24

6:00 am-3:02 pm

1 stop8h 02m

$212

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 9/25

8:40 pm-9:06 am

1 stop13h 26m

Lambert-St Louis

Sun 9/28

7:55 pm-7:45 pm

1 stop22h 50m

$225

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 9/18

10:24 am-4:05 pm

1 stop6h 41m

Lambert-St Louis

Sun 9/21

6:01 am-10:56 am

1 stop3h 55m

$229

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Wed 8/13

10:10 am-1:51 pm

1 stop4h 41m

Lambert-St Louis

Sat 8/16

5:15 am-11:30 am

1 stop5h 15m

$239

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Fri 9/19

5:20 pm-9:10 pm

1 stop4h 50m

Lambert-St Louis

Sun 9/21

7:23 am-2:43 pm

1 stop6h 20m

$249

KnoxvilleKansas City

TYS - MCI

TYSMCI

Knoxville McGhee Tyson

Wed 9/10

1:53 pm-6:56 pm

1 stop6h 03m

Kansas City

Sat 9/13

5:45 am-10:25 am

1 stop3h 40m

$249

KnoxvilleSpringfield

TYS - SGF

TYSSGF

Knoxville McGhee Tyson

Thu 11/27

5:45 am-2:39 pm

2 stops9h 54m

Springfield-Branson

Sat 12/6

9:05 am-6:09 pm

1 stop8h 04m

$299

KnoxvilleKansas City

TYS - MCI

TYSMCI

Knoxville McGhee Tyson

Fri 9/26

4:40 pm-11:30 pm

1 stop7h 50m

Kansas City

Tue 9/30

3:23 pm-10:50 pm

1 stop6h 27m

$319

KnoxvilleSpringfield

TYS - SGF

TYSSGF

Knoxville McGhee Tyson

Sun 8/10

7:44 pm-8:58 am

1 stop14h 14m

Springfield-Branson

Mon 8/11

8:21 pm-1:11 pm

1 stop15h 50m

$419

KnoxvilleSpringfield

TYS - SGF

TYSSGF

Knoxville McGhee Tyson

Sun 11/16

6:58 pm-8:48 am

1 stop14h 50m

Springfield-Branson

Thu 11/20

8:21 pm-10:14 am

1 stop12h 53m

$470

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Missouri from

How to get the cheapest flight ticket from Knoxville to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

In general, December is the cheapest month to fly from Knoxville to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $283. If you aren’t able to travel to Missouri during the month of December, then flying in April is also cheap. Prices for this month can be found on momondo for an average of $284.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Knoxville to Missouri is on a Wednesday when prices can be found for as low as $259. Flights from Knoxville to Missouri on a Monday will generally be more expensive and average around $539. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is at noon. momondo users have found flights departing from Knoxville to Missouri at noon for as low as $265. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the morning, with an average ticket price of $288. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Cheap Knoxville to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Missouri

Best Price Found

$117

Fastest flight time

3h 29m

Direct flights

None

Airports in Missouri

4 airports
The best one-way flight to Missouri from Knoxville in the past 72 hours is $117. The best round-trip flight deal from Knoxville to Missouri found on momondo in the last 72 hours is $212.
The fastest flight from Knoxville to Missouri takes 3h 29m
There are no direct flights from Knoxville to Missouri. Popular non-direct routes for this connection are Knoxville McGhee Tyson Airport - Kansas City Airport, Knoxville McGhee Tyson Airport - Lambert-St Louis Airport and Knoxville McGhee Tyson Airport - Springfield-Branson Airport.
There are 4 airports near Missouri: Kansas City (MCI), Springfield-Branson (SGF), Lambert-St Louis (STL), Joplin (JLN)
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  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Missouri?

    Prices for flights from Knoxville McGhee Tyson Airport to Missouri were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Missouri?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Missouri?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Missouri.

  • What documentation or ID do you need to fly to Missouri?

    The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Missouri

Compare and see reviews for airlines that fly from Knoxville to Missouri with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $198Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights
American AirlinesPriceFrom $198Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $228Free CancellationRating
8.0
7,981 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Missouri?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Missouri. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Missouri with flexible booking policies on momondo?

Yes. All flights to Missouri from Knoxville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Knoxville to Missouri?

momondo helps you find the best flight between Knoxville and Missouri by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Missouri right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Missouri, momondo offers a useful price alert feature which will track prices for flights to Missouri from Knoxville and alert you when they change.

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