What airlines fly to Iowa?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Iowa from Knoxville according to our data. American Airlines is the first choice among our users, with 64% of people opting to fly with this airline when traveling to Iowa. Keep in mind that there are 3 different airlines that fly to Iowa on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Iowa?

Allegiant Air, United Airlines, and Delta are the most popular carriers operating from Knoxville McGhee Tyson to Iowa

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Iowa?

Prices for flights from Knoxville McGhee Tyson Airport to Iowa are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Iowa?

There are 3 operators available for flights from Knoxville McGhee Tyson Airport to Iowa as of September 2026.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Iowa?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Iowa.

What documentation or ID do you need to fly to Iowa?

The travel and health documents required for your trip to Iowa can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Iowa. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$142 Cheap Flights from Knoxville to Iowa in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Iowa

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:06 pm - 9:31 pmTYS Knoxville McGhee Tyson-DSM Des Moines

8h 25m1 stop Sarasota Bradenton Intl

6:40 am - 8:38 pmDSM Des Moines-TYS Knoxville McGhee Tyson

36h 58m2 stops Philadelphia Orlando

$276Multiple Airlines

Thu, Oct 1 - Sun, Oct 4

10:00 am - 4:49 pmTYS Knoxville McGhee Tyson-OMA Omaha Eppley Airfield

7h 49m1 stop Charlotte Douglas

6:00 am - 2:05 pmOMA Omaha Eppley Airfield-TYS Knoxville McGhee Tyson

7h 05m1 stop Dallas/Fort Worth

$287American Airlines

Thu, Oct 29 - Tue, Nov 3

11:59 am - 7:28 pmTYS Knoxville McGhee Tyson-OMA Omaha Eppley Airfield

8h 29m1 stop Houston George Bush Intcntl

11:26 am - 4:59 pmOMA Omaha Eppley Airfield-TYS Knoxville McGhee Tyson

4h 33m1 stop Chicago O'Hare Intl

$287United Airlines

Thu, Oct 29 - Tue, Nov 3

8:47 am - 2:39 pmTYS Knoxville McGhee Tyson-OMA Omaha Eppley Airfield

6h 52m1 stop Atlanta Hartsfield-Jackson

8:00 am - 3:05 pmOMA Omaha Eppley Airfield-TYS Knoxville McGhee Tyson

6h 05m1 stop Atlanta Hartsfield-Jackson

$287Delta

Mon, Jan 11 - Tue, Jan 12

5:40 am - 9:43 amTYS Knoxville McGhee Tyson-OMA Omaha Eppley Airfield

5h 03m1 stop Atlanta Hartsfield-Jackson

10:40 am - 5:28 pmOMA Omaha Eppley Airfield-TYS Knoxville McGhee Tyson

5h 48m1 stop Atlanta Hartsfield-Jackson

$287Delta

Thu, Sep 24 - Thu, Oct 1

11:35 am - 3:38 pmTYS Knoxville McGhee Tyson-OMA Omaha Eppley Airfield

5h 03m1 stop Chicago O'Hare Intl

6:00 am - 2:05 pmOMA Omaha Eppley Airfield-TYS Knoxville McGhee Tyson

7h 05m1 stop Dallas/Fort Worth

$287American Airlines

Thu, Oct 29 - Tue, Nov 3

2:06 pm - 9:31 pmTYS Knoxville McGhee Tyson-DSM Des Moines

8h 25m1 stop Sarasota Bradenton Intl

6:40 am - 8:38 pmDSM Des Moines-TYS Knoxville McGhee Tyson

36h 58m2 stops Philadelphia Orlando

$291Multiple Airlines

Thu, Oct 1 - Sun, Oct 4

9:45 am - 5:43 pmTYS Knoxville McGhee Tyson-OMA Omaha Eppley Airfield

8h 58m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

11:26 am - 4:59 pmOMA Omaha Eppley Airfield-TYS Knoxville McGhee Tyson

4h 33m1 stop Chicago O'Hare Intl

$292United Airlines

Thu, Oct 29 - Tue, Nov 3

6:56 am - 10:56 amTYS Knoxville McGhee Tyson-OMA Omaha Eppley Airfield

5h 00m1 stop Charlotte Douglas

8:37 am - 4:48 pmOMA Omaha Eppley Airfield-TYS Knoxville McGhee Tyson

7h 11m2 stops Chicago O'Hare Intl Charlotte Douglas

$292American Airlines

Thu, Oct 29 - Tue, Nov 3

12:50 pm - 11:35 pmTYS Knoxville McGhee Tyson-OMA Omaha Eppley Airfield

11h 45m2 stops Orlando Chicago Midway

7:55 am - 7:45 pmOMA Omaha Eppley Airfield-TYS Knoxville McGhee Tyson

10h 50m2 stops Houston Hobby Nashville Intl

$318Southwest

Fri, Oct 30 - Tue, Nov 3

Cheap last minute flights

Enter your travel dates to find the best prices.

11:34 am - 4:05 pmTYS Knoxville McGhee Tyson-DSM Des Moines

29h 31m1 stop Tampa St. Petersburg

1:58 pm - 7:34 pmDSM Des Moines-TYS Knoxville McGhee Tyson

28h 36m1 stop Philadelphia

$432Allegiant Air

Thu, Sep 10 - Sun, Sep 13

5:38 pm - 2:14 pmTYS Knoxville McGhee Tyson-DSM Des Moines

21h 36m2 stops Orlando Sanford Intl Boston Logan Intl

1:58 pm - 7:34 pmDSM Des Moines-TYS Knoxville McGhee Tyson

28h 36m1 stop Philadelphia

$483Multiple Airlines

Thu, Sep 10 - Sun, Sep 13

6:00 pm - 11:04 pmTYS Knoxville McGhee Tyson-OMA Omaha Eppley Airfield

6h 04m1 stop Chicago O'Hare Intl

3:11 pm - 10:49 pmOMA Omaha Eppley Airfield-TYS Knoxville McGhee Tyson

6h 38m1 stop Chicago O'Hare Intl

$570United Airlines

Tue, Sep 8 - Thu, Sep 10

6:00 pm - 11:04 pmTYS Knoxville McGhee Tyson-OMA Omaha Eppley Airfield

6h 04m1 stop Chicago O'Hare Intl

6:00 am - 2:37 pmOMA Omaha Eppley Airfield-TYS Knoxville McGhee Tyson

7h 37m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$575United Airlines

Tue, Sep 8 - Thu, Sep 10

6:00 pm - 11:04 pmTYS Knoxville McGhee Tyson-OMA Omaha Eppley Airfield

6h 04m1 stop Chicago O'Hare Intl

3:11 pm - 10:49 pmOMA Omaha Eppley Airfield-TYS Knoxville McGhee Tyson

6h 38m1 stop Chicago O'Hare Intl

$635United Airlines

Tue, Sep 8 - Thu, Sep 10

1:53 pm - 5:57 pmTYS Knoxville McGhee Tyson-DSM Des Moines

5h 04m1 stop Chicago O'Hare Intl

1:35 pm - 10:44 pmDSM Des Moines-TYS Knoxville McGhee Tyson

8h 09m1 stop Denver Intl

$637United Airlines

Thu, Sep 10 - Sun, Sep 13

6:00 pm - 11:04 pmTYS Knoxville McGhee Tyson-OMA Omaha Eppley Airfield

6h 04m1 stop Chicago O'Hare Intl

6:00 am - 2:37 pmOMA Omaha Eppley Airfield-TYS Knoxville McGhee Tyson

7h 37m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$640United Airlines

Tue, Sep 8 - Thu, Sep 10

7:15 am - 4:19 pmTYS Knoxville McGhee Tyson-DSM Des Moines

10h 04m2 stops Houston George Bush Intcntl Denver Intl

3:22 pm - 10:49 pmDSM Des Moines-TYS Knoxville McGhee Tyson

6h 27m1 stop Chicago O'Hare Intl

$642United Airlines

Thu, Sep 10 - Sun, Sep 13

6:30 am - 10:17 amTYS Knoxville McGhee Tyson-DSM Des Moines

4h 47m1 stop Minneapolis St Paul

5:45 am - 11:23 amDSM Des Moines-TYS Knoxville McGhee Tyson

4h 38m1 stop Atlanta Hartsfield-Jackson

$977Delta

Thu, Sep 10 - Sun, Sep 13

5:40 am - 2:06 pmTYS Knoxville McGhee Tyson-DSM Des Moines

9h 26m2 stops Atlanta Hartsfield-Jackson Minneapolis St Paul

5:45 am - 11:23 amDSM Des Moines-TYS Knoxville McGhee Tyson

4h 38m1 stop Atlanta Hartsfield-Jackson

$1,540Delta

Thu, Sep 10 - Sun, Sep 13

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United Airlines flights from Knoxville to Iowa

Our best United Airlines deals on Knoxville to Iowa flight tickets

United Airlines

Sep 30

TYS6:00 amKnoxville McGhee Tyson

5h 31m

1 stop

DSM10:31 amDes Moines

Oct 7

DSM1:24 pmDes Moines

9h 35m

2 stops

TYS11:59 pmKnoxville McGhee Tyson

$313

United Airlines

Sep 18

TYS6:02 pmKnoxville McGhee Tyson

5h 33m

1 stop

MLI10:35 pmMoline Quad-City

Sep 22

MLI5:08 pmMoline Quad-City

6h 15m

1 stop

TYS12:23 amKnoxville McGhee Tyson

$349

United Airlines

Oct 28

TYS10:45 amKnoxville McGhee Tyson

4h 34m

1 stop

OMA2:19 pmOmaha Eppley Airfield

Oct 31

OMA1:02 pmOmaha Eppley Airfield

6h 52m

1 stop

TYS8:54 pmKnoxville McGhee Tyson

$367

Southwest flights from Knoxville to Iowa

Our best Southwest deals on Knoxville to Iowa flight tickets

Southwest

Jan 11

TYS7:00 amKnoxville McGhee Tyson

11h 15m

2 stops

OMA5:15 pmOmaha Eppley Airfield

Jan 12

OMA8:10 amOmaha Eppley Airfield

9h 30m

2 stops

TYS6:40 pmKnoxville McGhee Tyson

$324

Southwest

Sep 29

TYS3:00 pmKnoxville McGhee Tyson

7h 05m

1 stop

DSM9:05 pmDes Moines

Oct 5

DSM4:30 pmDes Moines

5h 15m

2 stops

TYS10:45 pmKnoxville McGhee Tyson

$348

Southwest

Sep 29

TYS12:45 pmKnoxville McGhee Tyson

10h 15m

2 stops

DSM10:00 pmDes Moines

Oct 5

DSM4:30 pmDes Moines

5h 15m

2 stops

TYS10:45 pmKnoxville McGhee Tyson

$353

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleDes Moines

TYS Knoxville McGhee Tyson - DSM Des Moines

TYSDSM

Knoxville McGhee Tyson

Thu 10/1

2:06 pm-9:31 pm

1 stop8h 25m

Des Moines

Sun 10/4

6:40 am-8:38 pm

2 stops36h 58m

$276

KnoxvilleOmaha

TYS Knoxville McGhee Tyson - OMA Omaha Eppley Airfield

TYSOMA

Knoxville McGhee Tyson

Thu 10/29

10:00 am-4:49 pm

1 stop7h 49m

Omaha Eppley Airfield

Tue 11/3

6:00 am-2:05 pm

1 stop7h 05m

$287

KnoxvilleOmaha

TYS Knoxville McGhee Tyson - OMA Omaha Eppley Airfield

TYSOMA

Knoxville McGhee Tyson

Thu 10/29

11:59 am-7:28 pm

1 stop8h 29m

Omaha Eppley Airfield

Tue 11/3

11:26 am-4:59 pm

1 stop4h 33m

$287

KnoxvilleOmaha

TYS Knoxville McGhee Tyson - OMA Omaha Eppley Airfield

TYSOMA

Knoxville McGhee Tyson

Mon 1/11

8:47 am-2:39 pm

1 stop6h 52m

Omaha Eppley Airfield

Tue 1/12

8:00 am-3:05 pm

1 stop6h 05m

$287

Quickest round-trip

KnoxvilleOmaha

TYS Knoxville McGhee Tyson - OMA Omaha Eppley Airfield

TYSOMA

Knoxville McGhee Tyson

Thu 9/24

5:40 am-9:43 am

1 stop5h 03m

Omaha Eppley Airfield

Thu 10/1

10:40 am-5:28 pm

1 stop5h 48m

$287

KnoxvilleOmaha

TYS Knoxville McGhee Tyson - OMA Omaha Eppley Airfield

TYSOMA

Knoxville McGhee Tyson

Thu 10/29

11:35 am-3:38 pm

1 stop5h 03m

Omaha Eppley Airfield

Tue 11/3

6:00 am-2:05 pm

1 stop7h 05m

$287

KnoxvilleDes Moines

TYS Knoxville McGhee Tyson - DSM Des Moines

TYSDSM

Knoxville McGhee Tyson

Thu 10/1

2:06 pm-9:31 pm

1 stop8h 25m

Des Moines

Sun 10/4

6:40 am-8:38 pm

2 stops36h 58m

$291

KnoxvilleOmaha

TYS Knoxville McGhee Tyson - OMA Omaha Eppley Airfield

TYSOMA

Knoxville McGhee Tyson

Thu 10/29

9:45 am-5:43 pm

2 stops8h 58m

Omaha Eppley Airfield

Tue 11/3

11:26 am-4:59 pm

1 stop4h 33m

$292

KnoxvilleOmaha

TYS Knoxville McGhee Tyson - OMA Omaha Eppley Airfield

TYSOMA

Knoxville McGhee Tyson

Thu 10/29

6:56 am-10:56 am

1 stop5h 00m

Omaha Eppley Airfield

Tue 11/3

8:37 am-4:48 pm

2 stops7h 11m

$292

KnoxvilleOmaha

TYS Knoxville McGhee Tyson - OMA Omaha Eppley Airfield

TYSOMA

Knoxville McGhee Tyson

Fri 10/30

12:50 pm-11:35 pm

2 stops11h 45m

Omaha Eppley Airfield

Tue 11/3

7:55 am-7:45 pm

2 stops10h 50m

$318

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Iowa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Iowa?

The month of December is another great option to travel to Iowa, with average flight prices from Knoxville averaging around $283.

Can stopping save me money on Knoxville to Iowa flights?

You could potentially save up to 22% on your flight if you consider stops on a Knoxville to Iowa flight.

Cheap Knoxville to Iowa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Iowa

Best Price Found	$142
Fastest flight time	4h 19m
Direct flights	None

The best one-way flight to Iowa from Knoxville in the past 72 hours is $142. The best round-trip flight deal from Knoxville to Iowa found on momondo in the last 72 hours is $276.

The fastest flight from Knoxville to Iowa takes 4h 19m

There are no direct flights from Knoxville to Iowa. There are no popular flight routes from Knoxville to Iowa.

Search flight deals

Frequently asked questions about flying from Knoxville to Iowa

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Iowa?
Prices for flights from Knoxville McGhee Tyson Airport to Iowa are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Iowa?
There are 3 operators available for flights from Knoxville McGhee Tyson Airport to Iowa as of September 2026.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Iowa?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Iowa.
What documentation or ID do you need to fly to Iowa?
The travel and health documents required for your trip to Iowa can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Iowa. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Iowa

Compare and see reviews for airlines that fly from Knoxville to Iowa with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $226	Free Cancellation	Rating 7.1 12,039 reviews		Search American Airlines flights
United Airlines	PriceFrom $284	Free Cancellation	Rating 7.4 10,173 reviews		Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Iowa?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Iowa. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Iowa with flexible booking policies on momondo?

Flights from Knoxville to Iowa with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Iowa?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Iowa.

I’m not ready to book a flight from Knoxville to Iowa right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Iowa flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.