What airlines fly to Iowa?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Iowa from Knoxville according to our data. American Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to Iowa. Keep in mind that there are 3 different airlines that fly to Iowa on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Iowa?

Allegiant Air, Delta, and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Iowa

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Iowa?

Prices for flights from Knoxville McGhee Tyson Airport to Iowa are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Iowa?

There are 3 operators available for flights from Knoxville McGhee Tyson Airport to Iowa as of June 2026.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Iowa?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Iowa.

What documentation or ID do you need to fly to Iowa?

The travel and health documents required for your trip to Iowa can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Iowa. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$153 Cheap Flights from Knoxville to Iowa in 2026

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Knoxville to Iowa

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:35 am - 10:02 pm

TYS

DSM

14h 27m

1 stop

5:12 pm - 10:24 pm

DSM

TYS

28h 12m

1 stop

$243Allegiant Air

Fri, Aug 7 - Sun, Aug 9

3:38 pm - 9:27 pm

TYS

DSM

6h 49m

1 stop

3:52 pm - 11:19 pm

DSM

TYS

6h 27m

1 stop

$245Allegiant Air

Thu, Jul 30 - Fri, Jul 31

8:32 pm - 7:30 pm

TYS

OMA

23h 58m

1 stop

8:15 pm - 7:24 pm

OMA

TYS

22h 09m

1 stop

$270Frontier

Wed, Jul 1 - Tue, Jul 7

8:19 pm - 7:15 pm

TYS

OMA

23h 56m

1 stop

8:15 pm - 7:24 pm

OMA

TYS

22h 09m

1 stop

$271Frontier

Wed, Aug 5 - Tue, Aug 11

7:15 am - 1:25 pm

TYS

OMA

7h 10m

1 stop

5:25 am - 11:10 am

OMA

TYS

4h 45m

1 stop

$307Delta

Tue, Jun 30 - Tue, Jul 7

6:00 am - 10:04 am

TYS

MLI

5h 04m

1 stop

2:31 pm - 8:48 pm

MLI

TYS

5h 17m

1 stop

$329United Airlines

Thu, Jul 2 - Sun, Jul 5

5:40 am - 10:16 am

TYS

MLI

5h 36m

1 stop

5:17 pm - 12:02 am

MLI

TYS

5h 45m

1 stop

$339Delta

Wed, Jun 17 - Sat, Jun 20

7:15 am - 10:41 am

TYS

MLI

4h 26m

1 stop

6:00 am - 3:49 pm

MLI

TYS

8h 49m

2 stops

$344American Airlines

Wed, Jun 17 - Sat, Jun 20

6:07 pm - 12:11 am

TYS

MLI

7h 04m

2 stops

6:00 am - 3:49 pm

MLI

TYS

8h 49m

2 stops

$349American Airlines

Wed, Jun 17 - Sat, Jun 20

7:00 am - 9:54 am

TYS

MLI

3h 54m

1 stop

1:15 pm - 8:53 pm

MLI

TYS

6h 38m

1 stop

$389United Airlines

Sat, Aug 15 - Wed, Aug 19

Frontier flights from Knoxville to Iowa

Our best Frontier deals on Knoxville to Iowa flight tickets

Frontier

Jul 29

TYS8:19 pmKnoxville McGhee Tyson

23h 56m

1 stop

OMA7:15 pmOmaha Eppley Airfield

Aug 4

OMA8:15 pmOmaha Eppley Airfield

22h 09m

1 stop

TYS7:24 pmKnoxville McGhee Tyson

$270

Frontier

Aug 5

TYS8:19 pmKnoxville McGhee Tyson

23h 56m

1 stop

OMA7:15 pmOmaha Eppley Airfield

Aug 11

OMA8:15 pmOmaha Eppley Airfield

22h 09m

1 stop

TYS7:24 pmKnoxville McGhee Tyson

$271

Frontier

Jul 17

TYS8:19 pmKnoxville McGhee Tyson

23h 56m

1 stop

OMA7:15 pmOmaha Eppley Airfield

Jul 21

OMA8:15 pmOmaha Eppley Airfield

22h 09m

1 stop

TYS7:24 pmKnoxville McGhee Tyson

$326

Delta flights from Knoxville to Iowa

Our best Delta deals on Knoxville to Iowa flight tickets

Delta

Jun 17

TYS5:40 amKnoxville McGhee Tyson

5h 36m

1 stop

MLI10:16 amMoline Quad-City

Jun 20

MLI5:17 pmMoline Quad-City

5h 45m

1 stop

TYS12:02 amKnoxville McGhee Tyson

$339

Delta

Jun 25

TYS7:46 pmKnoxville McGhee Tyson

5h 04m

1 stop

OMA11:50 pmOmaha Eppley Airfield

Jun 30

OMA6:25 amOmaha Eppley Airfield

7h 31m

1 stop

TYS2:56 pmKnoxville McGhee Tyson

$352

Delta

Jul 30

TYS7:15 amKnoxville McGhee Tyson

7h 07m

1 stop

OMA1:22 pmOmaha Eppley Airfield

Aug 4

OMA10:26 amOmaha Eppley Airfield

6h 16m

1 stop

TYS5:42 pmKnoxville McGhee Tyson

$357

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Fri 8/7

8:35 am-10:02 pm

1 stop14h 27m

Des Moines

Sun 8/9

5:12 pm-10:24 pm

1 stop28h 12m

$243

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Thu 7/30

3:38 pm-9:27 pm

1 stop6h 49m

Des Moines

Fri 7/31

3:52 pm-11:19 pm

1 stop6h 27m

$245

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Wed 7/1

8:32 pm-7:30 pm

1 stop23h 58m

Omaha Eppley Airfield

Tue 7/7

8:15 pm-7:24 pm

1 stop22h 09m

$270

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Wed 8/5

8:19 pm-7:15 pm

1 stop23h 56m

Omaha Eppley Airfield

Tue 8/11

8:15 pm-7:24 pm

1 stop22h 09m

$271

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Tue 6/30

7:15 am-1:25 pm

1 stop7h 10m

Omaha Eppley Airfield

Tue 7/7

5:25 am-11:10 am

1 stop4h 45m

$307

Quickest round-trip

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Thu 7/2

6:00 am-10:04 am

1 stop5h 04m

Moline Quad-City

Sun 7/5

2:31 pm-8:48 pm

1 stop5h 17m

$329

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Wed 6/17

5:40 am-10:16 am

1 stop5h 36m

Moline Quad-City

Sat 6/20

5:17 pm-12:02 am

1 stop5h 45m

$339

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Wed 6/17

7:15 am-10:41 am

1 stop4h 26m

Moline Quad-City

Sat 6/20

6:00 am-3:49 pm

2 stops8h 49m

$344

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Wed 6/17

6:07 pm-12:11 am

2 stops7h 04m

Moline Quad-City

Sat 6/20

6:00 am-3:49 pm

2 stops8h 49m

$349

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Sat 8/15

7:00 am-9:54 am

1 stop3h 54m

Moline Quad-City

Wed 8/19

1:15 pm-8:53 pm

1 stop6h 38m

$389

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Iowa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Iowa?

The month of November is another great option to travel to Iowa, with average flight prices from Knoxville averaging around $203.

Can stopping save me money on Knoxville to Iowa flights?

You could potentially save up to 48% on your flight if you consider stops on a Knoxville to Iowa flight.

Cheap Knoxville to Iowa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Iowa

Fastest flight time	3h 54m
Direct flights	None

The fastest flight from Knoxville to Iowa takes 3h 54m

There are no direct flights from Knoxville to Iowa. There are no popular flight routes from Knoxville to Iowa.

Search flight deals

Frequently asked questions about flying from Knoxville to Iowa

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Iowa?
Prices for flights from Knoxville McGhee Tyson Airport to Iowa are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Iowa?
There are 3 operators available for flights from Knoxville McGhee Tyson Airport to Iowa as of June 2026.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Iowa?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Iowa.
What documentation or ID do you need to fly to Iowa?
The travel and health documents required for your trip to Iowa can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Iowa. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Iowa

Compare and see reviews for airlines that fly from Knoxville to Iowa with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $226	Free Cancellation	Rating 7.1 11,649 reviews	Search American Airlines flights
Delta	PriceFrom $248	Free Cancellation	Rating 7.9 8,396 reviews	Search Delta flights
United Airlines	PriceFrom $341	Free Cancellation	Rating 7.4 9,777 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Iowa?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Iowa. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Iowa with flexible booking policies on momondo?

Flights from Knoxville to Iowa with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Iowa?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Iowa.

I’m not ready to book a flight from Knoxville to Iowa right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Iowa flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.