What airlines fly to Iowa?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Iowa from Knoxville according to our data. American Airlines is the first choice among our users, with 58% of people opting to fly with this airline when traveling to Iowa. Keep in mind that there are 3 different airlines that fly to Iowa on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Iowa?

Frontier, Allegiant Air, and Southwest are the most popular carriers operating from Knoxville McGhee Tyson to Iowa

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Iowa?

Prices for flights from Knoxville McGhee Tyson Airport to Iowa are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Iowa?

There are 3 operators available for flights from Knoxville McGhee Tyson Airport to Iowa as of April 2026.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Iowa?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Iowa.

What documentation or ID do you need to fly to Iowa?

The travel and health documents required for your trip to Iowa can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Iowa. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$121 Cheap Flights from Knoxville to Iowa in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Iowa

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:20 pm - 9:17 am

TYS

OMA

19h 57m

1 stop

8:19 pm - 1:59 pm

OMA

TYS

16h 40m

1 stop

$237Multiple Airlines

Wed, May 20 - Sat, May 23

3:40 pm - 10:06 pm

TYS

DSM

7h 26m

1 stop

2:59 pm - 2:58 pm

DSM

TYS

22h 59m

1 stop

$246Allegiant Air

Thu, Apr 30 - Mon, May 4

4:31 pm - 9:31 am

TYS

OMA

18h 00m

1 stop

6:01 pm - 9:40 am

OMA

TYS

14h 39m

1 stop

$268Allegiant Air

Thu, May 7 - Mon, May 11

12:50 pm - 8:45 pm

TYS

OMA

8h 55m

1 stop

6:10 am - 5:10 pm

OMA

TYS

10h 00m

1 stop

$300Southwest

Tue, May 19 - Wed, May 20

12:50 pm - 8:45 pm

TYS

OMA

8h 55m

1 stop

5:30 am - 5:10 pm

OMA

TYS

10h 40m

2 stops

$301Southwest

Tue, May 19 - Wed, May 20

8:48 pm - 11:54 pm

TYS

MLI

4h 06m

1 stop

4:24 pm - 9:58 pm

MLI

TYS

4h 34m

1 stop

$310American Airlines

Tue, May 19 - Tue, May 26

5:00 am - 11:43 am

TYS

OMA

7h 43m

2 stops

5:07 pm - 11:55 pm

OMA

TYS

5h 48m

1 stop

$316American Airlines

Thu, May 7 - Mon, May 11

5:40 am - 10:20 am

TYS

MLI

5h 40m

1 stop

5:17 pm - 12:01 am

MLI

TYS

5h 44m

1 stop

$329Delta

Tue, May 26 - Tue, Jun 2

5:40 am - 10:20 am

TYS

MLI

5h 40m

1 stop

5:17 pm - 12:01 am

MLI

TYS

5h 44m

1 stop

$334Delta

Tue, May 26 - Tue, Jun 2

5:45 am - 6:10 pm

TYS

LSE

13h 25m

2 stops

7:20 pm - 2:27 pm

LSE

TYS

18h 07m

2 stops

$677United Airlines

Tue, Jun 23 - Fri, Jun 26

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Allegiant Air flights from Knoxville to Iowa

Our best Allegiant Air deals on Knoxville to Iowa flight tickets

Allegiant Air

Apr 30

TYS3:40 pmKnoxville McGhee Tyson

7h 26m

1 stop

DSM10:06 pmDes Moines

May 4

DSM2:59 pmDes Moines

22h 59m

1 stop

TYS2:58 pmKnoxville McGhee Tyson

$246

Allegiant Air

May 7

TYS4:31 pmKnoxville McGhee Tyson

18h 00m

1 stop

OMA9:31 amOmaha Eppley Airfield

May 11

OMA6:01 pmOmaha Eppley Airfield

14h 39m

1 stop

TYS9:40 amKnoxville McGhee Tyson

$268

Allegiant Air

Jun 1

TYS1:36 pmKnoxville McGhee Tyson

10h 48m

1 stop

DSM11:24 pmDes Moines

Jun 4

DSM5:02 pmDes Moines

27h 48m

1 stop

TYS9:50 pmKnoxville McGhee Tyson

$272

Southwest flights from Knoxville to Iowa

Our best Southwest deals on Knoxville to Iowa flight tickets

Southwest

May 19

TYS12:50 pmKnoxville McGhee Tyson

8h 55m

1 stop

OMA8:45 pmOmaha Eppley Airfield

May 20

OMA6:10 amOmaha Eppley Airfield

10h 00m

1 stop

TYS5:10 pmKnoxville McGhee Tyson

$300

Southwest

May 19

TYS12:50 pmKnoxville McGhee Tyson

8h 55m

1 stop

OMA8:45 pmOmaha Eppley Airfield

May 20

OMA5:30 amOmaha Eppley Airfield

10h 40m

2 stops

TYS5:10 pmKnoxville McGhee Tyson

$301

Southwest

May 19

TYS7:05 amKnoxville McGhee Tyson

9h 35m

2 stops

OMA3:40 pmOmaha Eppley Airfield

May 20

OMA5:30 amOmaha Eppley Airfield

10h 40m

2 stops

TYS5:10 pmKnoxville McGhee Tyson

$306

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Wed 5/20

2:20 pm-9:17 am

1 stop19h 57m

Omaha Eppley Airfield

Sat 5/23

8:19 pm-1:59 pm

1 stop16h 40m

$237

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Thu 4/30

3:40 pm-10:06 pm

1 stop7h 26m

Des Moines

Mon 5/4

2:59 pm-2:58 pm

1 stop22h 59m

$246

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Thu 5/7

4:31 pm-9:31 am

1 stop18h 00m

Omaha Eppley Airfield

Mon 5/11

6:01 pm-9:40 am

1 stop14h 39m

$268

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Tue 5/19

12:50 pm-8:45 pm

1 stop8h 55m

Omaha Eppley Airfield

Wed 5/20

6:10 am-5:10 pm

1 stop10h 00m

$300

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Tue 5/19

12:50 pm-8:45 pm

1 stop8h 55m

Omaha Eppley Airfield

Wed 5/20

5:30 am-5:10 pm

2 stops10h 40m

$301

Quickest round-trip

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Tue 5/19

8:48 pm-11:54 pm

1 stop4h 06m

Moline Quad-City

Tue 5/26

4:24 pm-9:58 pm

1 stop4h 34m

$310

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Thu 5/7

5:00 am-11:43 am

2 stops7h 43m

Omaha Eppley Airfield

Mon 5/11

5:07 pm-11:55 pm

1 stop5h 48m

$316

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Tue 5/26

5:40 am-10:20 am

1 stop5h 40m

Moline Quad-City

Tue 6/2

5:17 pm-12:01 am

1 stop5h 44m

$329

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Tue 5/26

5:40 am-10:20 am

1 stop5h 40m

Moline Quad-City

Tue 6/2

5:17 pm-12:01 am

1 stop5h 44m

$334

KnoxvilleLa Crosse

TYS - LSE

TYSLSE

Knoxville McGhee Tyson

Tue 6/23

5:45 am-6:10 pm

2 stops13h 25m

La Crosse

Fri 6/26

7:20 pm-2:27 pm

2 stops18h 07m

$677

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Iowa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Knoxville to Iowa flights?

You could potentially save up to 48% on your flight if you consider stops on a Knoxville to Iowa flight.

Cheap Knoxville to Iowa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Iowa

Fastest flight time	4h 06m
Direct flights	None

The fastest flight from Knoxville to Iowa takes 4h 06m

There are no direct flights from Knoxville to Iowa. There are no popular flight routes from Knoxville to Iowa.

Search flight deals

Frequently asked questions about flying from Knoxville to Iowa

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Iowa?
Prices for flights from Knoxville McGhee Tyson Airport to Iowa are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Iowa?
There are 3 operators available for flights from Knoxville McGhee Tyson Airport to Iowa as of April 2026.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Iowa?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Iowa.
What documentation or ID do you need to fly to Iowa?
The travel and health documents required for your trip to Iowa can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Iowa. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Iowa

Compare and see reviews for airlines that fly from Knoxville to Iowa with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $223	Free Cancellation	Rating 7.4 9,607 reviews	Search United Airlines flights
American Airlines	PriceFrom $226	Free Cancellation	Rating 7.1 11,625 reviews	Search American Airlines flights
Delta	PriceFrom $248	Free Cancellation	Rating 7.9 8,422 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Iowa?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Iowa. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Iowa with flexible booking policies on momondo?

Flights from Knoxville to Iowa with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Iowa?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Iowa.

I’m not ready to book a flight from Knoxville to Iowa right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Iowa flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.