What airlines fly to Iowa?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Iowa from Knoxville according to our data. American Airlines is the first choice among our users, with 62% of people opting to fly with this airline when traveling to Iowa. Keep in mind that there are 3 different airlines that fly to Iowa on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Iowa?

United Airlines, Southwest, and American Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Iowa

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Iowa?

Prices for flights from Knoxville McGhee Tyson Airport to Iowa are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Iowa?

There are 3 operators available for flights from Knoxville McGhee Tyson Airport to Iowa as of March 2026.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Iowa?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Iowa.

What documentation or ID do you need to fly to Iowa?

The travel and health documents required for your trip to Iowa can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Iowa. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$88 Cheap Flights from Knoxville to Iowa in 2026

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Find the cheapest flights from Knoxville to Iowa

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:00 am - 9:58 am

TYS

MLI

3h 58m

1 stop

3:20 pm - 10:34 pm

MLI

TYS

6h 14m

1 stop

$289United Airlines

Thu, Apr 23 - Sun, Apr 26

5:00 am - 12:21 pm

TYS

MLI

8h 21m

2 stops

12:51 pm - 8:18 pm

MLI

TYS

6h 27m

1 stop

$294American Airlines

Thu, Apr 23 - Sun, Apr 26

3:46 pm - 10:31 pm

TYS

DSM

7h 45m

1 stop

4:25 pm - 6:21 pm

DSM

TYS

24h 56m

1 stop

$298Allegiant Air

Thu, May 28 - Tue, Jun 2

7:07 am - 10:42 am

TYS

MLI

4h 35m

1 stop

6:00 am - 10:59 am

MLI

TYS

3h 59m

1 stop

$299American Airlines

Thu, May 28 - Thu, Jun 4

2:06 pm - 12:33 pm

TYS

DSM

23h 27m

1 stop

7:51 pm - 10:53 pm

DSM

TYS

26h 02m

1 stop

$309Allegiant Air

Mon, Mar 16 - Fri, Mar 20

7:00 am - 10:30 am

TYS

DSM

4h 30m

1 stop

5:30 am - 3:06 pm

DSM

TYS

8h 36m

1 stop

$310United Airlines

Fri, Mar 27 - Tue, Mar 31

10:03 pm - 4:19 pm

TYS

MLI

19h 16m

1 stop

4:25 pm - 10:16 pm

MLI

TYS

28h 51m

1 stop

$310Allegiant Air

Fri, May 22 - Wed, Jun 3

3:45 pm - 8:25 pm

TYS

OMA

5h 40m

1 stop

1:55 pm - 8:05 pm

OMA

TYS

5h 10m

1 stop

$327Southwest

Fri, Mar 27 - Tue, Mar 31

3:45 pm - 8:25 pm

TYS

OMA

5h 40m

1 stop

10:35 am - 9:10 pm

OMA

TYS

9h 35m

2 stops

$332Southwest

Fri, Mar 27 - Tue, Mar 31

7:10 am - 10:48 am

TYS

DSM

4h 38m

1 stop

10:28 am - 4:43 pm

DSM

TYS

5h 15m

1 stop

$349Delta

Fri, Apr 3 - Sun, Apr 5

Southwest flights from Knoxville to Iowa

Our best Southwest deals on Knoxville to Iowa flight tickets

Southwest

Mar 27

TYS3:45 pmKnoxville McGhee Tyson

5h 40m

1 stop

OMA8:25 pmOmaha Eppley Airfield

Mar 31

OMA1:55 pmOmaha Eppley Airfield

5h 10m

1 stop

TYS8:05 pmKnoxville McGhee Tyson

$327

Southwest

Mar 27

TYS3:45 pmKnoxville McGhee Tyson

5h 40m

1 stop

OMA8:25 pmOmaha Eppley Airfield

Mar 31

OMA10:35 amOmaha Eppley Airfield

9h 35m

2 stops

TYS9:10 pmKnoxville McGhee Tyson

$332

Southwest

Aug 19

TYS1:55 pmKnoxville McGhee Tyson

6h 25m

1 stop

OMA7:20 pmOmaha Eppley Airfield

Aug 22

OMA8:10 amOmaha Eppley Airfield

10h 10m

2 stops

TYS7:20 pmKnoxville McGhee Tyson

$342

Allegiant Air flights from Knoxville to Iowa

Our best Allegiant Air deals on Knoxville to Iowa flight tickets

Allegiant Air

May 28

TYS3:46 pmKnoxville McGhee Tyson

7h 45m

1 stop

DSM10:31 pmDes Moines

Jun 2

DSM4:25 pmDes Moines

24h 56m

1 stop

TYS6:21 pmKnoxville McGhee Tyson

$298

Allegiant Air

Mar 16

TYS2:06 pmKnoxville McGhee Tyson

23h 27m

1 stop

DSM12:33 pmDes Moines

Mar 20

DSM7:51 pmDes Moines

26h 02m

1 stop

TYS10:53 pmKnoxville McGhee Tyson

$309

Allegiant Air

May 22

TYS10:03 pmKnoxville McGhee Tyson

19h 16m

1 stop

MLI4:19 pmMoline Quad-City

Jun 3

MLI4:25 pmMoline Quad-City

28h 51m

1 stop

TYS10:16 pmKnoxville McGhee Tyson

$310

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Thu 4/23

7:00 am-9:58 am

1 stop3h 58m

Moline Quad-City

Sun 4/26

3:20 pm-10:34 pm

1 stop6h 14m

$289

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Thu 4/23

5:00 am-12:21 pm

2 stops8h 21m

Moline Quad-City

Sun 4/26

12:51 pm-8:18 pm

1 stop6h 27m

$294

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Thu 5/28

3:46 pm-10:31 pm

1 stop7h 45m

Des Moines

Tue 6/2

4:25 pm-6:21 pm

1 stop24h 56m

$298

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Thu 5/28

7:07 am-10:42 am

1 stop4h 35m

Moline Quad-City

Thu 6/4

6:00 am-10:59 am

1 stop3h 59m

$299

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Mon 3/16

2:06 pm-12:33 pm

1 stop23h 27m

Des Moines

Fri 3/20

7:51 pm-10:53 pm

1 stop26h 02m

$309

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Fri 3/27

7:00 am-10:30 am

1 stop4h 30m

Des Moines

Tue 3/31

5:30 am-3:06 pm

1 stop8h 36m

$310

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

Fri 5/22

10:03 pm-4:19 pm

1 stop19h 16m

Moline Quad-City

Wed 6/3

4:25 pm-10:16 pm

1 stop28h 51m

$310

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Fri 3/27

3:45 pm-8:25 pm

1 stop5h 40m

Omaha Eppley Airfield

Tue 3/31

1:55 pm-8:05 pm

1 stop5h 10m

$327

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

Fri 3/27

3:45 pm-8:25 pm

1 stop5h 40m

Omaha Eppley Airfield

Tue 3/31

10:35 am-9:10 pm

2 stops9h 35m

$332

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Fri 4/3

7:10 am-10:48 am

1 stop4h 38m

Des Moines

Sun 4/5

10:28 am-4:43 pm

1 stop5h 15m

$349

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Iowa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Knoxville to Iowa flights?

You could potentially save up to 48% on your flight if you consider stops on a Knoxville to Iowa flight.

Cheap Knoxville to Iowa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Iowa

Fastest flight time	3h 58m
Direct flights	None

The fastest flight from Knoxville to Iowa takes 3h 58m

There are no direct flights from Knoxville to Iowa. There are no popular flight routes from Knoxville to Iowa.

Search flight deals

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Iowa?
Prices for flights from Knoxville McGhee Tyson Airport to Iowa are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Iowa?
There are 3 operators available for flights from Knoxville McGhee Tyson Airport to Iowa as of March 2026.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Iowa?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Iowa.
What documentation or ID do you need to fly to Iowa?
The travel and health documents required for your trip to Iowa can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Iowa. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Iowa

Compare and see reviews for airlines that fly from Knoxville to Iowa with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $223	Free Cancellation	Rating 7.4 9,389 reviews	Search United Airlines flights
Delta	PriceFrom $232	Free Cancellation	Rating 7.9 8,248 reviews	Search Delta flights
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 11,381 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Iowa?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Iowa. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Iowa with flexible booking policies on momondo?

Flights from Knoxville to Iowa with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to Iowa?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Iowa.

I’m not ready to book a flight from Knoxville to Iowa right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Iowa flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.