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Cheap flights from Islip, New York to Greenville from $182

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Islip, New York to Greenville departing on 8/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Islip, New York to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
4:40 pm - 8:15 pm
ISP
-
GSP
3h 35m
1 stop
Southwest Logo
1:50 pm - 10:40 pm
GSP
-
ISP
8h 50m
1 stop
$366Southwest
Tue, Jun 30 - Tue, Jul 7
Southwest Logo
5:50 pm - 9:40 pm
ISP
-
GSP
3h 50m
1 stop
Southwest Logo
1:55 pm - 11:40 pm
GSP
-
ISP
9h 45m
1 stop
$392Southwest
Fri, Jul 17 - Fri, Jul 24
Southwest Logo
5:50 pm - 9:40 pm
ISP
-
GSP
3h 50m
1 stop
Southwest Logo
8:30 am - 2:30 pm
GSP
-
ISP
6h 00m
1 stop
$397Southwest
Fri, Jul 17 - Mon, Jul 20
Southwest Logo
5:50 pm - 9:40 pm
ISP
-
GSP
3h 50m
1 stop
Southwest Logo
8:25 am - 10:40 pm
GSP
-
ISP
14h 15m
2 stops
$398Southwest
Mon, Jul 20 - Wed, Jul 22
Southwest Logo
4:40 pm - 8:15 pm
ISP
-
GSP
3h 35m
1 stop
Southwest Logo
1:50 pm - 10:40 pm
GSP
-
ISP
8h 50m
1 stop
$402Southwest
Tue, Jun 30 - Tue, Jul 7
Southwest Logo
12:30 pm - 10:55 pm
ISP
-
GSP
10h 25m
2 stops
Southwest Logo
1:55 pm - 11:40 pm
GSP
-
ISP
9h 45m
1 stop
$403Southwest
Fri, Jul 17 - Fri, Jul 24
Southwest Logo
3:05 pm - 10:55 pm
ISP
-
GSP
7h 50m
2 stops
Southwest Logo
12:55 pm - 11:40 pm
GSP
-
ISP
10h 45m
2 stops
$413Southwest
Fri, Jul 17 - Mon, Jul 20
Southwest Logo
12:30 pm - 10:55 pm
ISP
-
GSP
10h 25m
2 stops
Southwest Logo
1:55 pm - 11:45 pm
GSP
-
ISP
9h 50m
2 stops
$423Southwest
Fri, Jul 17 - Fri, Jul 24
Multiple Airlines Logo
5:50 pm - 9:46 am
ISP
-
GSP
15h 56m
2 stops
Multiple Airlines Logo
8:28 pm - 3:56 pm
GSP
-
ISP
19h 28m
1 stop
$430Multiple Airlines
Thu, Jun 11 - Mon, Jun 15
Southwest Logo
5:50 pm - 9:40 pm
ISP
-
GSP
3h 50m
1 stop
Southwest Logo
7:55 am - 11:45 am
GSP
-
ISP
3h 50m
1 stop
$437Southwest
Fri, Jul 24 - Sun, Jul 26

Southwest flights from Islip, New York to Greenville

Our best Southwest deals on Islip, New York to Greenville flight tickets
Southwest
Jun 30
ISP4:40 pmIslip Long Island
3h 35m
1 stop
GSP8:15 pmGreenville
Jul 7
GSP1:50 pmGreenville
8h 50m
1 stop
ISP10:40 pmIslip Long Island
$366
Southwest
Jul 17
ISP5:50 pmIslip Long Island
3h 50m
1 stop
GSP9:40 pmGreenville
Jul 24
GSP1:55 pmGreenville
9h 45m
1 stop
ISP11:40 pmIslip Long Island
$392
Southwest
Jul 17
ISP5:50 pmIslip Long Island
3h 50m
1 stop
GSP9:40 pmGreenville
Jul 20
GSP8:30 amGreenville
6h 00m
1 stop
ISP2:30 pmIslip Long Island
$397

Breeze Airways flights from Islip, New York to Greenville

Our best Breeze Airways deals on Islip, New York to Greenville flight tickets
Breeze Airways
Jun 25
ISP5:50 pmIslip Long Island
15h 56m
2 stops
GSP9:46 amGreenville
Jun 29
GSP10:26 amGreenville
27h 02m
2 stops
ISP1:28 pmIslip Long Island
$799
Breeze Airways
Jun 25
ISP5:50 pmIslip Long Island
15h 56m
2 stops
GSP9:46 amGreenville
Jun 29
GSP10:26 amGreenville
27h 02m
2 stops
ISP1:28 pmIslip Long Island
$809
Breeze Airways
Jun 25
ISP5:50 pmIslip Long Island
15h 56m
2 stops
GSP9:46 amGreenville
Jun 29
GSP10:26 amGreenville
27h 02m
2 stops
ISP1:28 pmIslip Long Island
$829

momondo Fare Finder

 
Customize your flight search to find flights from Islip, New York to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 30, 2026.
Use the filters below to find and compare flights from Islip, New York to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Tue 6/30

4:40 pm-8:15 pm

1 stop3h 35m

Greenville

Tue 7/7

1:50 pm-10:40 pm

1 stop8h 50m

$366

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Fri 7/17

5:50 pm-9:40 pm

1 stop3h 50m

Greenville

Fri 7/24

1:55 pm-11:40 pm

1 stop9h 45m

$392

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Fri 7/17

5:50 pm-9:40 pm

1 stop3h 50m

Greenville

Mon 7/20

8:30 am-2:30 pm

1 stop6h 00m

$397

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Mon 7/20

5:50 pm-9:40 pm

1 stop3h 50m

Greenville

Wed 7/22

8:25 am-10:40 pm

2 stops14h 15m

$398

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Tue 6/30

4:40 pm-8:15 pm

1 stop3h 35m

Greenville

Tue 7/7

1:50 pm-10:40 pm

1 stop8h 50m

$402

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Fri 7/17

12:30 pm-10:55 pm

2 stops10h 25m

Greenville

Fri 7/24

1:55 pm-11:40 pm

1 stop9h 45m

$403

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Fri 7/17

3:05 pm-10:55 pm

2 stops7h 50m

Greenville

Mon 7/20

12:55 pm-11:40 pm

2 stops10h 45m

$413

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Fri 7/17

12:30 pm-10:55 pm

2 stops10h 25m

Greenville

Fri 7/24

1:55 pm-11:45 pm

2 stops9h 50m

$423

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Thu 6/11

5:50 pm-9:46 am

2 stops15h 56m

Greenville

Mon 6/15

8:28 pm-3:56 pm

1 stop19h 28m

$430
Quickest round-trip

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

Fri 7/24

5:50 pm-9:40 pm

1 stop3h 50m

Greenville

Sun 7/26

7:55 am-11:45 am

1 stop3h 50m

$437

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
1
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See travel insights to Greenville from

How to get the cheapest flight ticket from Islip, New York to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Islip, New York and Greenville?

What is the cheapest month to fly to Greenville?

The month of March is another great option to travel to Greenville, with average flight prices from Islip, New York averaging around $353.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from Islip, New York. The lowest ticket price found for a Wednesday departure recently was $305. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $445. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is at noon. Flights from Islip, New York to Greenville during this time can be as low as $318. Flights to Greenville are more costly in the morning, with an average ticket price of $337. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Islip, New York to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Islip, New York to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Islip, New York to Greenville (ISP to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Islip, New York to Greenville

Fastest flight time

3h 35m

Direct flights

None
The fastest flight from Islip, New York to Greenville takes 3h 35m
There are no direct flights from Islip, New York to Greenville. There are no popular flight routes from Islip, New York to Greenville.
Search flight deals

Frequently asked questions about flying from Islip, New York to Greenville

  • How far is Islip Long Island to Greenville by plane?

    There are 644.2 mi between Islip Long Island and Greenville. Typically, this will take 3h 35m by plane in normal conditions.

  • When did momondo last update prices for flights from Islip Long Island Airport to Greenville Airport?

    Prices for flights from Islip Long Island Airport to Greenville Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Islip Long Island Airport to Greenville Airport?

  • How old do you have to be to fly from Islip Long Island Airport to Greenville Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Islip Long Island Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Islip, New York to Greenville?

Best airlines flying from Islip, New York to Greenville

Compare and see reviews for airlines that fly from Islip, New York to Greenville with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $256Free CancellationRating
8.0
4,262 reviews
Search Southwest flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Islip to Greenville?

Finding the right flight to Greenville from Islip is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Greenville quick and easy, saving you time and money.

Can I find flights from Islip to Greenville with flexible booking policies on momondo?

All flight searches from Islip to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Islip to Greenville?

Once all potential Islip to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Islip to Greenville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Greenville from Islip. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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