What airlines fly to Greenville?

American Airlines, Spirit Airlines and United Airlines are the top three most popular airlines that fly to Greenville from Islip, New York according to our data. American Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 8 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Islip Long Island Airport to Greenville Airport?

Prices for flights from Islip Long Island Airport to Greenville Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Islip Long Island Airport to Greenville Airport?

The number of operators available for flights from Islip Long Island Airport to Greenville Airport is 1 as of December 2025.

How old do you have to be to fly from Islip Long Island Airport to Greenville Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Islip Long Island Airport to Greenville Airport.

What documentation or ID do you need to fly to Greenville Airport?

The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$241 Cheap Flights from Islip to Greenville in 2025/26

1 adult

0 bags

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Find the cheapest flights from Islip, New York to Greenville

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:40 pm - 3:59 pm

ISP

GSP

19h 19m1 stop

4:43 pm - 8:09 pm

GSP

ISP

27h 26m2 stops

$241Multiple Airlines

dim., janv. 11 - jeu., janv. 15

8:40 pm - 3:59 pm

ISP

GSP

19h 19m1 stop

9:48 am - 5:52 pm

GSP

ISP

32h 04m2 stops

$253Multiple Airlines

dim., janv. 11 - ven., janv. 16

8:40 pm - 3:59 pm

ISP

GSP

19h 19m1 stop

4:07 pm - 5:52 pm

GSP

ISP

25h 45m1 stop

$281Multiple Airlines

dim., janv. 11 - ven., janv. 16

7:35 pm - 9:07 pm

ISP

GSP

25h 32m1 stop

4:43 pm - 8:09 pm

GSP

ISP

27h 26m2 stops

$286Multiple Airlines

sam., janv. 10 - jeu., janv. 15

7:35 pm - 9:07 pm

ISP

GSP

25h 32m1 stop

9:48 am - 5:52 pm

GSP

ISP

32h 04m2 stops

$298Multiple Airlines

sam., janv. 10 - ven., janv. 16

8:33 am - 7:38 pm

ISP

GSP

11h 05m1 stop

5:13 pm - 2:39 pm

GSP

ISP

21h 26m2 stops

$303Multiple Airlines

ven., févr. 27 - dim., mars 1

7:35 pm - 9:07 pm

ISP

GSP

25h 32m1 stop

4:07 pm - 5:52 pm

GSP

ISP

25h 45m1 stop

$325Multiple Airlines

sam., janv. 10 - ven., janv. 16

5:35 pm - 9:45 pm

ISP

GSP

4h 10m1 stop

10:05 am - 4:15 pm

GSP

ISP

6h 10m1 stop

$330Southwest

ven., févr. 20 - mar., févr. 24

5:35 am - 10:10 am

ISP

GSP

4h 35m1 stop

11:15 am - 9:55 pm

GSP

ISP

10h 40m2 stops

$335Southwest

ven., févr. 20 - mar., févr. 24

11:55 am - 9:45 pm

ISP

GSP

9h 50m2 stops

11:15 am - 9:55 pm

GSP

ISP

10h 40m2 stops

$340Southwest

ven., févr. 20 - mar., févr. 24

Southwest flights from Islip, New York to Greenville

Our best Southwest deals on Islip, New York to Greenville flight tickets

Southwest

Feb 20

ISP5:35 pmIslip Long Island

4h 10m

1 stop

GSP9:45 pmGreenville

Feb 24

GSP10:05 amGreenville

6h 10m

1 stop

ISP4:15 pmIslip Long Island

$330

Find similar

Southwest

Feb 20

ISP5:35 amIslip Long Island

4h 35m

1 stop

GSP10:10 amGreenville

Feb 24

GSP11:15 amGreenville

10h 40m

2 stops

ISP9:55 pmIslip Long Island

$335

Find similar

Southwest

Feb 20

ISP11:55 amIslip Long Island

9h 50m

2 stops

GSP9:45 pmGreenville

Feb 24

GSP11:15 amGreenville

10h 40m

2 stops

ISP9:55 pmIslip Long Island

$340

Find similar

Breeze Airways flights from Islip, New York to Greenville

Our best Breeze Airways deals on Islip, New York to Greenville flight tickets

Breeze Airways

Jan 10

ISP7:35 pmIslip Long Island

25h 32m

1 stop

GSP9:07 pmGreenville

Jan 15

GSP4:55 pmGreenville

25h 45m

1 stop

ISP6:40 pmIslip Long Island

$370

Find similar

Breeze Airways

Dec 24

ISP5:54 pmIslip Long Island

14h 59m

1 stop

GSP8:53 amGreenville

Dec 25

GSP2:06 pmGreenville

28h 22m

1 stop

ISP6:28 pmIslip Long Island

$505

Find similar

Breeze Airways

Jan 1

ISP11:40 amIslip Long Island

9h 34m

2 stops

GSP9:14 pmGreenville

Jan 5

GSP9:46 pmGreenville

37h 24m

2 stops

ISP11:10 amIslip Long Island

$641

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Islip, New York to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

dim. 1/11

8:40 pm-3:59 pm

1 stop19h 19m

Greenville

jeu. 1/15

4:43 pm-8:09 pm

2 stops27h 26m

$241

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

dim. 1/11

8:40 pm-3:59 pm

1 stop19h 19m

Greenville

ven. 1/16

9:48 am-5:52 pm

2 stops32h 04m

$253

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

dim. 1/11

8:40 pm-3:59 pm

1 stop19h 19m

Greenville

ven. 1/16

4:07 pm-5:52 pm

1 stop25h 45m

$281

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

sam. 1/10

7:35 pm-9:07 pm

1 stop25h 32m

Greenville

jeu. 1/15

4:43 pm-8:09 pm

2 stops27h 26m

$286

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

sam. 1/10

7:35 pm-9:07 pm

1 stop25h 32m

Greenville

ven. 1/16

9:48 am-5:52 pm

2 stops32h 04m

$298

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

ven. 2/27

8:33 am-7:38 pm

1 stop11h 05m

Greenville

dim. 3/1

5:13 pm-2:39 pm

2 stops21h 26m

$303

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

sam. 1/10

7:35 pm-9:07 pm

1 stop25h 32m

Greenville

ven. 1/16

4:07 pm-5:52 pm

1 stop25h 45m

$325

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

ven. 2/20

5:35 pm-9:45 pm

1 stop4h 10m

Greenville

mar. 2/24

10:05 am-4:15 pm

1 stop6h 10m

$330

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

ven. 2/20

5:35 am-10:10 am

1 stop4h 35m

Greenville

mar. 2/24

11:15 am-9:55 pm

2 stops10h 40m

$335

IslipGreenville

ISP - GSP

ISPGSP

Islip Long Island

ven. 2/20

11:55 am-9:45 pm

2 stops9h 50m

Greenville

mar. 2/24

11:15 am-9:55 pm

2 stops10h 40m

$340

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Islip, New York to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Greenville?

According to our data, Saturday is the cheapest day to fly to Greenville from Islip, New York. The lowest ticket price found for a Saturday departure recently was $280. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $335. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the evening. Flights from Islip, New York to Greenville during this time can be as low as $294. Flights to Greenville are more costly in the afternoon, with an average ticket price of $301. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Islip, New York to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Islip, New York to Greenville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Islip, New York to Greenville (ISP to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Islip, New York to Greenville

Fastest flight time	4h 05m
Direct flights	None

The fastest flight from Islip, New York to Greenville takes 4h 05m

There are no direct flights from Islip, New York to Greenville. There are no popular flight routes from Islip, New York to Greenville.

Search flight deals

How far is Islip Long Island to Greenville by plane?
There are 644.2 mi between Islip Long Island and Greenville. Typically, this will take 4h 05m by plane in normal conditions.
When did momondo last update prices for flights from Islip Long Island Airport to Greenville Airport?
Prices for flights from Islip Long Island Airport to Greenville Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Islip Long Island Airport to Greenville Airport?
The number of operators available for flights from Islip Long Island Airport to Greenville Airport is 1 as of December 2025.
How old do you have to be to fly from Islip Long Island Airport to Greenville Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Islip Long Island Airport to Greenville Airport.
What documentation or ID do you need to fly to Greenville Airport?
The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Islip, New York to Greenville?
Based on momondo bookings for flights between Islip, New York and Greenville, the leading airline is Southwest, making up 100% of the total bookings.

Best airlines flying from Islip, New York to Greenville

Compare and see reviews for airlines that fly from Islip, New York to Greenville with momondo

Airline	Rating	Free Cancellation	Price
Southwest	PriceFrom $218	Free Cancellation	Rating 7.9 4,250 reviews		Search Southwest flights

Anderson

Simpsonville

Greenwood

Seneca

Greer

Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Islip to Greenville?

Finding the right flight to Greenville from Islip is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Greenville quick and easy, saving you time and money.

Can I find flights from Islip to Greenville with flexible booking policies on momondo?

All flight searches from Islip to Greenville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Islip to Greenville?

Once all potential Islip to Greenville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Islip to Greenville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Greenville from Islip. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.