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Cheap flights from Iowa to Missouri from $49

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Missouri departing on 10/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Iowa to Missouri

Cheap round-trip flights

Southwest Logo
8:25 am - 9:35 amDSM-STL
1h 10mnonstop
Southwest Logo
8:25 pm - 9:35 pmSTL-DSM
1h 10mnonstop
$134Southwest
Find Deal
Fri, Oct 31 - Mon, Nov 3
Frontier Logo
8:51 pm - 9:07 amOMA-STL
12h 16m1 stop
Frontier Logo
7:45 pm - 8:06 pmSTL-OMA
24h 21m1 stop
$136Frontier
Find Deal
Fri, Oct 31 - Sun, Nov 2
American Airlines Logo
7:30 am - 1:44 pmDSM-STL
6h 14m1 stop
American Airlines Logo
8:49 am - 3:03 pmSTL-DSM
6h 14m1 stop
$159American Airlines
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Sat, Oct 11 - Sat, Oct 18
Delta Logo
5:15 pm - 11:40 pmDSM-STL
6h 25m1 stop
Delta Logo
6:30 am - 10:22 amSTL-DSM
3h 52m1 stop
$177Delta
Find Deal
Tue, Mar 3 - Wed, Mar 4
Delta Logo
10:55 am - 8:39 pmDSM-STL
9h 44m2 stops
Delta Logo
6:30 am - 10:22 amSTL-DSM
3h 52m1 stop
$182Delta
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Tue, Mar 3 - Wed, Mar 4
United Airlines Logo
6:30 am - 10:49 amDSM-STL
4h 19m1 stop
United Airlines Logo
5:00 am - 10:32 amSTL-DSM
5h 32m1 stop
$219United Airlines
Find Deal
Thu, Oct 16 - Thu, Oct 23
American Airlines Logo
3:38 pm - 7:10 pmALO-STL
3h 32m1 stop
American Airlines Logo
8:05 pm - 11:38 pmSTL-ALO
3h 33m1 stop
$229American Airlines
Find Deal
Thu, Oct 2 - Mon, Oct 6
United Airlines Logo
6:30 am - 10:49 amDSM-STL
4h 19m1 stop
United Airlines Logo
6:30 am - 10:30 amSTL-DSM
4h 00m1 stop
$243United Airlines
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Thu, Oct 23 - Sun, Oct 26
Multiple Airlines Logo
1:10 pm - 12:40 amOMA-MCI
11h 30m1 stop
Multiple Airlines Logo
8:28 pm - 8:06 pmMCI-OMA
23h 38m1 stop
$251Multiple Airlines
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Mon, Nov 10 - Thu, Nov 13
Multiple Airlines Logo
7:38 pm - 5:55 pmOMA-MCI
22h 17m2 stops
Multiple Airlines Logo
8:38 pm - 8:04 pmMCI-OMA
23h 26m1 stop
$253Multiple Airlines
Find Deal
Fri, Oct 10 - Thu, Oct 16

United Airlines flights from Iowa to Missouri

Our best United Airlines deals on Iowa to Missouri flight tickets
United Airlines
Oct 16
DSM6:30 amDes Moines
4h 19m
1 stop
STL10:49 amLambert-St Louis
Oct 23
STL5:00 amLambert-St Louis
5h 32m
1 stop
DSM10:32 amDes Moines
$219
Find similar
United Airlines
Oct 23
DSM6:30 amDes Moines
4h 19m
1 stop
STL10:49 amLambert-St Louis
Oct 26
STL6:30 amLambert-St Louis
4h 00m
1 stop
DSM10:30 amDes Moines
$243
Find similar
United Airlines
Oct 22
DSM11:31 amDes Moines
4h 13m
1 stop
STL3:44 pmLambert-St Louis
Oct 26
STL6:30 amLambert-St Louis
4h 00m
1 stop
DSM10:30 amDes Moines
$244
Find similar

Southwest flights from Iowa to Missouri

Our best Southwest deals on Iowa to Missouri flight tickets
Southwest
Oct 31
DSM8:25 amDes Moines
1h 10m
STL9:35 amLambert-St Louis
Nov 3
STL8:25 pmLambert-St Louis
1h 10m
DSM9:35 pmDes Moines
$134
Find similar
Southwest
Oct 31
DSM6:25 amDes Moines
8h 20m
1 stop
STL2:45 pmLambert-St Louis
Nov 3
STL8:25 pmLambert-St Louis
1h 10m
DSM9:35 pmDes Moines
$150
Find similar
Southwest
Oct 28
DSM6:20 amDes Moines
1h 10m
STL7:30 amLambert-St Louis
Oct 30
STL9:50 amLambert-St Louis
1h 10m
DSM11:00 amDes Moines
$157
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 10/31

8:25 am-9:35 am

Nonstop1h 10m

Lambert-St Louis

Mon 11/3

8:25 pm-9:35 pm

Nonstop1h 10m

$134

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Fri 10/31

8:51 pm-9:07 am

1 stop12h 16m

Lambert-St Louis

Sun 11/2

7:45 pm-8:06 pm

1 stop24h 21m

$136

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Sat 10/11

7:30 am-1:44 pm

1 stop6h 14m

Lambert-St Louis

Sat 10/18

8:49 am-3:03 pm

1 stop6h 14m

$159

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 3/3

5:15 pm-11:40 pm

1 stop6h 25m

Lambert-St Louis

Wed 3/4

6:30 am-10:22 am

1 stop3h 52m

$177

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 3/3

10:55 am-8:39 pm

2 stops9h 44m

Lambert-St Louis

Wed 3/4

6:30 am-10:22 am

1 stop3h 52m

$182

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 10/16

6:30 am-10:49 am

1 stop4h 19m

Lambert-St Louis

Thu 10/23

5:00 am-10:32 am

1 stop5h 32m

$219

WaterlooSt. Louis

ALO - STL

ALOSTL

Waterloo

Thu 10/2

3:38 pm-7:10 pm

1 stop3h 32m

Lambert-St Louis

Mon 10/6

8:05 pm-11:38 pm

1 stop3h 33m

$229

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 10/23

6:30 am-10:49 am

1 stop4h 19m

Lambert-St Louis

Sun 10/26

6:30 am-10:30 am

1 stop4h 00m

$243

OmahaKansas City

OMA - MCI

OMAMCI

Omaha Eppley Airfield

Mon 11/10

1:10 pm-12:40 am

1 stop11h 30m

Kansas City

Thu 11/13

8:28 pm-8:06 pm

1 stop23h 38m

$251

OmahaKansas City

OMA - MCI

OMAMCI

Omaha Eppley Airfield

Fri 10/10

7:38 pm-5:55 pm

2 stops22h 17m

Kansas City

Thu 10/16

8:38 pm-8:04 pm

1 stop23h 26m

$253

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Missouri from

How to get the cheapest flight ticket from Iowa to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

In general, August is the cheapest month to fly from Iowa to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $225. If you aren’t able to travel to Missouri during the month of August, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $233.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Iowa to Missouri is on a Tuesday when prices can be found for as low as $377. Flights from Iowa to Missouri on a Saturday will generally be more expensive and average around $431. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is in the afternoon. momondo users have found flights departing from Iowa to Missouri in the afternoon for as low as $399. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the morning, with an average ticket price of $411. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Iowa to Missouri flight route?

Fly from Burlington to Lambert-St Louis for the best Iowa - Missouri flight prices

What cabin class options are available on Iowa to Missouri flights?

There is only 1 cabin class available to choose from on Iowa to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Iowa to Missouri flights?

No. A direct flight is the cheapest option for a flight between Iowa to Missouri.

Cheap Iowa to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Missouri

Best Price Found

$159

Fastest flight time

1h 05m

Direct flights

Every day

Airports in Missouri

1 airport
The best one-way flight to Missouri from Iowa in the past 72 hours is $159. The best round-trip flight deal from Iowa to Missouri found on momondo in the last 72 hours is $105.
The fastest flight from Iowa to Missouri takes 1h 05m
Direct flights go from Iowa to Missouri every day.
There is 1 airport near Missouri: Lambert-St Louis (STL)
Search flight deals

  • When did momondo last update prices for flights from Iowa to Missouri?

    Prices for flights from Iowa to Missouri are updated daily.

  • How many operators does momondo search for flights from Iowa to Missouri?

  • How old do you have to be to fly from Iowa to Missouri?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Missouri.

  • What documentation or ID do you need to fly to Missouri?

    The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Iowa to Missouri?

Best airlines flying from Iowa to Missouri

Compare and see reviews for airlines that fly from Iowa to Missouri with momondo
Airline
Rating
Free Cancellation
Price
Southern / MokulelePriceFrom $61Free CancellationRating
6.3
25 reviews
Search Southern / Mokulele flights
SouthwestPriceFrom $97Free CancellationRating
8.0
4,242 reviews
Search Southwest flights
American AirlinesPriceFrom $218Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $218Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Missouri?

Finding the right flight to Missouri from Iowa is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Missouri quick and easy, saving you time and money.

Can I find flights from Iowa to Missouri with flexible booking policies on momondo?

Yes. All flights to Missouri from Iowa on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Iowa to Missouri?

Once all potential Iowa to Missouri flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Iowa to Missouri right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Missouri from Iowa. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Missouri trip

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