What airlines fly to Missouri?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Missouri from Iowa according to our data. United Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 3 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

How long is the flight from Iowa to Missouri?

The flight from Iowa to Missouri depends on which airports you’re departing and arriving from and whether or not you have a layover. If you fly from Des Moines (a popular airport in Iowa) to St. Louis (the most popular airport in Missouri), then the flight time is 3h 25m on average. If you fly from Waterloo (another popular airport in Iowa) to St. Louis, then the average flight time is 3h 39m.

What is the cheapest airline that flies from Iowa to Missouri?

Delta, Southwest, and American Airlines are the most popular carriers operating from Iowa to Missouri

When did momondo last update prices for flights from Iowa to Missouri?

Prices for flights from Iowa to Missouri are updated daily.

How many operators does momondo search for flights from Iowa to Missouri?

As of November 2026, there are 3 operators available to choose from for flights from Iowa to Missouri.

How old do you have to be to fly from Iowa to Missouri?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Missouri.

What documentation or ID do you need to fly to Missouri?

The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$139 Cheap Flights from Iowa to Missouri in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Iowa to Missouri

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:35 pm - 10:57 amDSM Des Moines-STL Lambert-St Louis

14h 22m1 stop Denver Intl

7:54 pm - 7:42 pmSTL Lambert-St Louis-DSM Des Moines

23h 48m1 stop Denver Intl

$234Frontier

Thu, Dec 3 - Wed, Dec 9

9:31 am - 4:34 pmDSM Des Moines-STL Lambert-St Louis

7h 03m1 stop Chicago O'Hare Intl

5:02 am - 8:53 amSTL Lambert-St Louis-DSM Des Moines

3h 51m1 stop Chicago O'Hare Intl

$237American Airlines

Thu, Nov 26 - Thu, Dec 3

1:30 pm - 4:55 pmDSM Des Moines-STL Lambert-St Louis

3h 25m1 stop Chicago Midway

2:20 pm - 10:05 pmSTL Lambert-St Louis-DSM Des Moines

7h 45m2 stops Atlanta Hartsfield-Jackson Chicago Midway

$242Southwest

Thu, Nov 26 - Thu, Dec 3

3:30 pm - 10:00 pmDSM Des Moines-STL Lambert-St Louis

6h 30m1 stop Chicago Midway

11:55 am - 10:05 pmSTL Lambert-St Louis-DSM Des Moines

10h 10m2 stops Dallas Love Field Chicago Midway

$242Southwest

Thu, Dec 3 - Wed, Dec 9

8:00 am - 12:13 pmDSM Des Moines-STL Lambert-St Louis

4h 13m1 stop Chicago O'Hare Intl

6:45 pm - 11:14 pmSTL Lambert-St Louis-DSM Des Moines

4h 29m1 stop Chicago O'Hare Intl

$287United Airlines

Fri, Jan 8 - Sat, Jan 9

8:00 am - 12:10 pmDSM Des Moines-STL Lambert-St Louis

4h 10m1 stop Chicago O'Hare Intl

6:50 pm - 10:59 pmSTL Lambert-St Louis-DSM Des Moines

4h 09m1 stop Chicago O'Hare Intl

$302United Airlines

Fri, Nov 20 - Sun, Nov 22

6:15 am - 9:52 amCID Cedar Rapids-MCI Kansas City

3h 37m1 stop Minneapolis St Paul

6:00 am - 10:20 amMCI Kansas City-CID Cedar Rapids

4h 20m1 stop Minneapolis St Paul

$309Delta

Tue, Nov 24 - Sat, Nov 28

5:30 pm - 11:18 pmCID Cedar Rapids-STL Lambert-St Louis

5h 48m1 stop Minneapolis St Paul

6:30 am - 10:13 amSTL Lambert-St Louis-CID Cedar Rapids

3h 43m1 stop Minneapolis St Paul

$309Delta

Fri, Mar 26 - Sun, Mar 28

8:28 pm - 12:24 amCID Cedar Rapids-MCI Kansas City

3h 56m1 stop Chicago O'Hare Intl

7:20 pm - 12:16 amMCI Kansas City-CID Cedar Rapids

4h 56m1 stop Chicago O'Hare Intl

$309American Airlines

Fri, Nov 27 - Fri, Dec 4

6:29 pm - 12:36 amCID Cedar Rapids-MCI Kansas City

6h 07m1 stop Chicago O'Hare Intl

5:17 am - 11:29 amMCI Kansas City-CID Cedar Rapids

6h 12m1 stop Chicago O'Hare Intl

$309American Airlines

Fri, Dec 4 - Sun, Dec 6

Cheap last minute flights

Enter your travel dates to find the best prices.

1:58 pm - 6:17 pmDSM Des Moines-STL Lambert-St Louis

4h 19m1 stop Chicago O'Hare Intl

5:00 am - 8:46 amSTL Lambert-St Louis-DSM Des Moines

3h 46m1 stop Chicago O'Hare Intl

$539American Airlines

Tue, Nov 3 - Thu, Nov 5

7:26 pm - 11:59 pmDSM Des Moines-STL Lambert-St Louis

4h 33m1 stop Chicago O'Hare Intl

8:15 pm - 12:26 amSTL Lambert-St Louis-DSM Des Moines

4h 11m1 stop Chicago O'Hare Intl

$539American Airlines

Fri, Nov 6 - Sun, Nov 8

9:55 am - 3:43 pmDSM Des Moines-STL Lambert-St Louis

5h 48m1 stop Chicago O'Hare Intl

10:53 am - 5:28 pmSTL Lambert-St Louis-DSM Des Moines

6h 35m1 stop Chicago O'Hare Intl

$539United Airlines

Tue, Nov 3 - Thu, Nov 5

5:25 am - 10:05 amDSM Des Moines-STL Lambert-St Louis

4h 40m1 stop Chicago Midway

7:15 pm - 11:05 pmSTL Lambert-St Louis-DSM Des Moines

3h 50m1 stop Chicago Midway

$539Southwest

Fri, Nov 6 - Sun, Nov 8

6:00 am - 4:00 pmDSM Des Moines-STL Lambert-St Louis

10h 00m2 stops Chicago Midway Nashville Intl

6:10 am - 1:10 pmSTL Lambert-St Louis-DSM Des Moines

7h 00m1 stop Denver Intl

$544Southwest

Tue, Nov 3 - Thu, Nov 5

1:58 pm - 6:17 pmDSM Des Moines-STL Lambert-St Louis

4h 19m1 stop Chicago O'Hare Intl

8:15 pm - 12:26 amSTL Lambert-St Louis-DSM Des Moines

4h 11m1 stop Chicago O'Hare Intl

$722American Airlines

Tue, Nov 3 - Thu, Nov 5

6:00 am - 10:32 amSUX Sioux City Sioux Gateway-STL Lambert-St Louis

4h 32m1 stop Chicago O'Hare Intl

4:39 pm - 11:43 pmSTL Lambert-St Louis-SUX Sioux City Sioux Gateway

7h 04m1 stop Denver Intl

$797United Airlines

Tue, Nov 3 - Thu, Nov 5

6:55 am - 3:37 pmDSM Des Moines-STL Lambert-St Louis

8h 42m2 stops Minneapolis St Paul Detroit Metropolitan Wayne County

6:00 am - 10:42 amSTL Lambert-St Louis-DSM Des Moines

4h 42m1 stop Atlanta Hartsfield-Jackson

$844Delta

Tue, Nov 3 - Thu, Nov 5

6:45 pm - 11:24 pmDSM Des Moines-STL Lambert-St Louis

4h 39m1 stop Chicago O'Hare Intl

1:00 pm - 9:55 pmSTL Lambert-St Louis-DSM Des Moines

8h 55m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$937United Airlines

Fri, Nov 6 - Sun, Nov 8

6:55 am - 3:37 pmDSM Des Moines-STL Lambert-St Louis

8h 42m2 stops Minneapolis St Paul Detroit Metropolitan Wayne County

10:35 am - 7:11 pmSTL Lambert-St Louis-DSM Des Moines

8h 36m2 stops Detroit Metropolitan Wayne County Minneapolis St Paul

$1,389Delta

Fri, Nov 6 - Sun, Nov 8

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Delta flights from Iowa to Missouri

Our best Delta deals on Iowa to Missouri flight tickets

Delta

Nov 23

DSM6:45 amDes Moines

5h 36m

1 stop

STL12:21 pmLambert-St Louis

Nov 28

STL6:13 amLambert-St Louis

4h 06m

1 stop

DSM10:19 amDes Moines

$336

Delta

Nov 23

DSM11:00 amDes Moines

6h 41m

2 stops

STL5:41 pmLambert-St Louis

Nov 28

STL6:13 amLambert-St Louis

4h 06m

1 stop

DSM10:19 amDes Moines

$490

Delta

Nov 22

DSM6:45 amDes Moines

6h 38m

2 stops

STL1:23 pmLambert-St Louis

Nov 29

STL6:13 amLambert-St Louis

4h 06m

1 stop

DSM10:19 amDes Moines

$539

American Airlines flights from Iowa to Missouri

Our best American Airlines deals on Iowa to Missouri flight tickets

American Airlines

Nov 26

DSM9:31 amDes Moines

7h 03m

1 stop

STL4:34 pmLambert-St Louis

Dec 3

STL5:02 amLambert-St Louis

3h 51m

1 stop

DSM8:53 amDes Moines

$237

American Airlines

Nov 19

CID5:00 amCedar Rapids

5h 16m

1 stop

STL10:16 amLambert-St Louis

Nov 22

STL6:00 amLambert-St Louis

4h 23m

1 stop

CID10:23 amCedar Rapids

$309

American Airlines

Nov 29

CID8:28 pmCedar Rapids

3h 56m

1 stop

MCI12:24 amKansas City

Dec 6

MCI5:17 amKansas City

5h 07m

1 stop

CID10:24 amCedar Rapids

$319

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSt. Louis

DSM Des Moines - STL Lambert-St Louis

DSMSTL

Des Moines

Thu 12/3

8:35 pm-10:57 am

1 stop14h 22m

Lambert-St Louis

Wed 12/9

7:54 pm-7:42 pm

1 stop23h 48m

$234

Des MoinesSt. Louis

DSM Des Moines - STL Lambert-St Louis

DSMSTL

Des Moines

Thu 11/26

9:31 am-4:34 pm

1 stop7h 03m

Lambert-St Louis

Thu 12/3

5:02 am-8:53 am

1 stop3h 51m

$237

Des MoinesSt. Louis

DSM Des Moines - STL Lambert-St Louis

DSMSTL

Des Moines

Thu 11/26

1:30 pm-4:55 pm

1 stop3h 25m

Lambert-St Louis

Thu 12/3

2:20 pm-10:05 pm

2 stops7h 45m

$242

Des MoinesSt. Louis

DSM Des Moines - STL Lambert-St Louis

DSMSTL

Des Moines

Thu 12/3

3:30 pm-10:00 pm

1 stop6h 30m

Lambert-St Louis

Wed 12/9

11:55 am-10:05 pm

2 stops10h 10m

$242

Des MoinesSt. Louis

DSM Des Moines - STL Lambert-St Louis

DSMSTL

Des Moines

Fri 1/8

8:00 am-12:13 pm

1 stop4h 13m

Lambert-St Louis

Sat 1/9

6:45 pm-11:14 pm

1 stop4h 29m

$287

Des MoinesSt. Louis

DSM Des Moines - STL Lambert-St Louis

DSMSTL

Des Moines

Fri 11/20

8:00 am-12:10 pm

1 stop4h 10m

Lambert-St Louis

Sun 11/22

6:50 pm-10:59 pm

1 stop4h 09m

$302

Quickest round-trip

Cedar RapidsKansas City

CID Cedar Rapids - MCI Kansas City

CIDMCI

Cedar Rapids

Tue 11/24

6:15 am-9:52 am

1 stop3h 37m

Kansas City

Sat 11/28

6:00 am-10:20 am

1 stop4h 20m

$309

Cedar RapidsSt. Louis

CID Cedar Rapids - STL Lambert-St Louis

CIDSTL

Cedar Rapids

Fri 3/26

5:30 pm-11:18 pm

1 stop5h 48m

Lambert-St Louis

Sun 3/28

6:30 am-10:13 am

1 stop3h 43m

$309

Cedar RapidsKansas City

CID Cedar Rapids - MCI Kansas City

CIDMCI

Cedar Rapids

Fri 11/27

8:28 pm-12:24 am

1 stop3h 56m

Kansas City

Fri 12/4

7:20 pm-12:16 am

1 stop4h 56m

$309

Cedar RapidsKansas City

CID Cedar Rapids - MCI Kansas City

CIDMCI

Cedar Rapids

Fri 12/4

6:29 pm-12:36 am

1 stop6h 07m

Kansas City

Sun 12/6

5:17 am-11:29 am

1 stop6h 12m

$309

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Iowa to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Missouri?

In general, July is the cheapest month to fly from Iowa to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you aren’t able to travel to Missouri during the month of July, then flying in May is also cheap. Prices for this month can be found on momondo for an average of $116.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Iowa to Missouri is on a Wednesday when prices can be found for as low as $364. Flights from Iowa to Missouri on a Friday will generally be more expensive and average around $486. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Missouri?

According to our data, the cheapest time of day to fly to Missouri is in the afternoon. momondo users have found flights departing from Iowa to Missouri in the afternoon for as low as $413. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the morning, with an average ticket price of $425. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Iowa to Missouri flight route?

Fly from Des Moines to Lambert-St Louis for the best Iowa - Missouri flight prices

What cabin class options are available on Iowa to Missouri flights?

There is only 1 cabin class available to choose from on Iowa to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Iowa to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Missouri

Best Price Found	$139
Fastest flight time	1h 10m
Direct flights	None

The best one-way flight to Missouri from Iowa in the past 72 hours is $139. The best round-trip flight deal from Iowa to Missouri found on momondo in the last 72 hours is $234.

The fastest flight from Iowa to Missouri takes 1h 10m

There are no direct flights from Iowa to Missouri. Popular non-direct route for this connection is Des Moines Airport - Lambert-St Louis Airport.

Search flight deals

Frequently asked questions about flying from Iowa to Missouri

When did momondo last update prices for flights from Iowa to Missouri?
Prices for flights from Iowa to Missouri are updated daily.
How many operators does momondo search for flights from Iowa to Missouri?
As of November 2026, there are 3 operators available to choose from for flights from Iowa to Missouri.
How old do you have to be to fly from Iowa to Missouri?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Missouri.
What documentation or ID do you need to fly to Missouri?
The travel and health documents required for your trip to Missouri can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Missouri. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Iowa to Missouri?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Iowa to Missouri is Airbus A319 (23.08% of total bookings). The next most popular plane models are Airbus A320-100/200 (21.15%), Airbus A320neo (13.46%), and Boeing 737-800 (9.62%).

Best airlines flying from Iowa to Missouri

Compare and see reviews for airlines that fly from Iowa to Missouri with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $158	Free Cancellation	Rating 7.0 12,213 reviews	Search American Airlines flights
Delta	PriceFrom $180	Free Cancellation	Rating 7.8 8,696 reviews	Search Delta flights
United Airlines	PriceFrom $244	Free Cancellation	Rating 7.3 10,462 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Missouri?

Finding the right flight to Missouri from Iowa is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Missouri quick and easy, saving you time and money.

Can I find flights from Iowa to Missouri with flexible booking policies on momondo?

Yes. All flights to Missouri from Iowa on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Iowa to Missouri?

Once all potential Iowa to Missouri flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Iowa to Missouri right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Missouri from Iowa. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.