What is the cheapest airline that flies from Iowa to Mississippi?

Delta, American Airlines, and Frontier are the most popular carriers operating from Iowa to Mississippi

When did momondo last update prices for flights from Iowa to Mississippi?

Prices for flights from Iowa to Mississippi are updated daily.

How many operators does momondo search for flights from Iowa to Mississippi?

As of February 2026, there are 4 operators available to choose from for flights from Iowa to Mississippi.

How old do you have to be to fly from Iowa to Mississippi?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Mississippi.

What documentation or ID do you need to fly to Mississippi?

The travel and health documents required for your trip to Mississippi can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mississippi. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$139 Cheap Flights from Iowa to Mississippi in 2026

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Find the cheapest flights from Iowa to Mississippi

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 12:41 pm

MLI

MEM

6h 41m

1 stop

10:37 am - 4:32 pm

MEM

MLI

5h 55m

1 stop

$249Delta

Tue, Mar 31 - Mon, Apr 6

10:02 am - 2:39 pm

DSM

MEM

4h 37m

1 stop

2:16 pm - 7:26 pm

MEM

DSM

5h 10m

1 stop

$251United Airlines

Sat, May 9 - Sat, May 16

2:02 pm - 10:53 pm

MLI

MEM

8h 51m

2 stops

7:23 pm - 11:37 pm

MEM

MLI

4h 14m

1 stop

$254American Airlines

Tue, Mar 31 - Mon, Apr 6

6:30 am - 10:59 am

MLI

MEM

4h 29m

1 stop

7:30 am - 2:12 pm

MEM

MLI

6h 42m

1 stop

$259United Airlines

Sat, Mar 7 - Tue, Mar 10

7:09 pm - 12:03 am

MLI

MEM

4h 54m

1 stop

8:23 am - 6:35 pm

MEM

MLI

10h 12m

2 stops

$264American Airlines

Sat, Mar 7 - Tue, Mar 10

5:20 pm - 11:28 pm

DSM

MOB

6h 08m

1 stop

6:15 am - 10:48 am

MOB

DSM

4h 33m

1 stop

$269Delta

Wed, Apr 1 - Wed, Apr 8

7:00 am - 7:17 pm

DSM

MEM

36h 17m

2 stops

2:53 pm - 7:16 pm

MEM

DSM

28h 23m

1 stop

$270Multiple Airlines

Sun, Mar 8 - Thu, Mar 12

8:30 am - 4:45 pm

DSM

MEM

32h 15m

2 stops

2:53 pm - 7:16 pm

MEM

DSM

28h 23m

1 stop

$276Multiple Airlines

Thu, Mar 19 - Thu, Mar 26

6:40 am - 2:00 pm

DSM

MEM

7h 20m

2 stops

5:25 am - 8:55 pm

MEM

DSM

15h 30m

2 stops

$310Southwest

Sat, May 9 - Sat, May 16

5:15 am - 2:00 pm

OMA

MEM

8h 45m

2 stops

5:25 am - 1:25 pm

MEM

OMA

8h 00m

2 stops

$331Southwest

Sat, Apr 11 - Sat, Apr 18

American Airlines flights from Iowa to Mississippi

Our best American Airlines deals on Iowa to Mississippi flight tickets

American Airlines

Mar 31

MLI2:02 pmMoline Quad-City

8h 51m

2 stops

MEM10:53 pmMemphis

Apr 6

MEM7:23 pmMemphis

4h 14m

1 stop

MLI11:37 pmMoline Quad-City

$254

American Airlines

Mar 7

MLI7:09 pmMoline Quad-City

4h 54m

1 stop

MEM12:03 amMemphis

Mar 10

MEM8:23 amMemphis

10h 12m

2 stops

MLI6:35 pmMoline Quad-City

$264

American Airlines

Mar 7

MLI2:02 pmMoline Quad-City

9h 49m

2 stops

MEM11:51 pmMemphis

Mar 10

MEM8:23 amMemphis

10h 12m

2 stops

MLI6:35 pmMoline Quad-City

$269

United Airlines flights from Iowa to Mississippi

Our best United Airlines deals on Iowa to Mississippi flight tickets

United Airlines

May 9

DSM10:02 amDes Moines

4h 37m

1 stop

MEM2:39 pmMemphis

May 16

MEM2:16 pmMemphis

5h 10m

1 stop

DSM7:26 pmDes Moines

$251

United Airlines

Mar 7

MLI6:30 amMoline Quad-City

4h 29m

1 stop

MEM10:59 amMemphis

Mar 10

MEM7:30 amMemphis

6h 42m

1 stop

MLI2:12 pmMoline Quad-City

$259

United Airlines

Mar 31

MLI8:30 amMoline Quad-City

6h 09m

1 stop

MEM2:39 pmMemphis

Apr 6

MEM6:37 pmMemphis

5h 20m

1 stop

MLI11:57 pmMoline Quad-City

$273

Fly from

Fly to

Route

Depart

Return

Price

MolineMemphis

MLI - MEM

MLIMEM

Moline Quad-City

Tue 3/31

6:00 am-12:41 pm

1 stop6h 41m

Memphis

Mon 4/6

10:37 am-4:32 pm

1 stop5h 55m

$249

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 5/9

10:02 am-2:39 pm

1 stop4h 37m

Memphis

Sat 5/16

2:16 pm-7:26 pm

1 stop5h 10m

$251

MolineMemphis

MLI - MEM

MLIMEM

Moline Quad-City

Tue 3/31

2:02 pm-10:53 pm

2 stops8h 51m

Memphis

Mon 4/6

7:23 pm-11:37 pm

1 stop4h 14m

$254

MolineMemphis

MLI - MEM

MLIMEM

Moline Quad-City

Sat 3/7

6:30 am-10:59 am

1 stop4h 29m

Memphis

Tue 3/10

7:30 am-2:12 pm

1 stop6h 42m

$259

MolineMemphis

MLI - MEM

MLIMEM

Moline Quad-City

Sat 3/7

7:09 pm-12:03 am

1 stop4h 54m

Memphis

Tue 3/10

8:23 am-6:35 pm

2 stops10h 12m

$264

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Wed 4/1

5:20 pm-11:28 pm

1 stop6h 08m

Mobile

Wed 4/8

6:15 am-10:48 am

1 stop4h 33m

$269

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sun 3/8

7:00 am-7:17 pm

2 stops36h 17m

Memphis

Thu 3/12

2:53 pm-7:16 pm

1 stop28h 23m

$270

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Thu 3/19

8:30 am-4:45 pm

2 stops32h 15m

Memphis

Thu 3/26

2:53 pm-7:16 pm

1 stop28h 23m

$276

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 5/9

6:40 am-2:00 pm

2 stops7h 20m

Memphis

Sat 5/16

5:25 am-8:55 pm

2 stops15h 30m

$310

OmahaMemphis

OMA - MEM

OMAMEM

Omaha Eppley Airfield

Sat 4/11

5:15 am-2:00 pm

2 stops8h 45m

Memphis

Sat 4/18

5:25 am-1:25 pm

2 stops8h 00m

$331

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Iowa to Mississippi

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Iowa to Mississippi flights?

You could potentially save up to 11% on your flight if you consider stops on a Iowa to Mississippi flight.

Cheap Iowa to Mississippi flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Mississippi

Fastest flight time	4h 21m
Direct flights	None

The fastest flight from Iowa to Mississippi takes 4h 21m

There are no direct flights from Iowa to Mississippi. There are no popular flight routes from Iowa to Mississippi.

Search flight deals

When did momondo last update prices for flights from Iowa to Mississippi?
Prices for flights from Iowa to Mississippi are updated daily.
How many operators does momondo search for flights from Iowa to Mississippi?
As of February 2026, there are 4 operators available to choose from for flights from Iowa to Mississippi.
How old do you have to be to fly from Iowa to Mississippi?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Mississippi.
What documentation or ID do you need to fly to Mississippi?
The travel and health documents required for your trip to Mississippi can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mississippi. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Iowa to Mississippi

Compare and see reviews for airlines that fly from Iowa to Mississippi with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 11,340 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Mississippi?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Iowa to Mississippi. momondo saves you time and could save you money on your trip.

Can I find flights from Iowa to Mississippi with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Iowa to Mississippi flights to just show those with flexible booking policies.

How can momondo help me find flights from Iowa to Mississippi?

Once you have performed a search for Iowa to Mississippi flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Iowa to Mississippi right now. Can momondo alert me if prices change?

Price alerts on flights to Mississippi from Iowa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.