What is the cheapest airline that flies from Iowa to Mississippi?

American Airlines, Delta, and United Airlines are the most popular carriers operating from Iowa to Mississippi

When did momondo last update prices for flights from Iowa to Mississippi?

Prices for flights from Iowa to Mississippi are updated daily.

How many operators does momondo search for flights from Iowa to Mississippi?

As of September 2025, there are 4 operators available to choose from for flights from Iowa to Mississippi.

How old do you have to be to fly from Iowa to Mississippi?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Mississippi.

What documentation or ID do you need to fly to Mississippi?

The travel and health documents required for your trip to Mississippi can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mississippi. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$140 Cheap Flights from Iowa to Mississippi in 2025/26

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Find the cheapest flights from Iowa to Mississippi

Round-trip

One-way

Last minute

Cheap round-trip flights

2:25 pm - 5:27 pmDSM-MEM

27h 02m1 stop

8:10 pm - 1:52 pmMEM-DSM

17h 42m1 stop

$185Frontier

Find Deal

Sun, Oct 5 - Thu, Oct 9

5:15 pm - 10:48 pmDSM-MOB

5h 33m1 stop

3:45 pm - 10:30 pmMOB-DSM

6h 45m1 stop

$249Delta

Find Deal

Sat, Oct 18 - Tue, Oct 21

11:38 am - 5:51 pmOMA-MOB

6h 13m1 stop

6:27 pm - 12:37 amMOB-OMA

6h 10m1 stop

$249American Airlines

Find Deal

Sat, Oct 18 - Sat, Oct 25

5:55 pm - 11:08 pmCID-GPT

5h 13m1 stop

4:54 pm - 11:59 pmGPT-CID

7h 05m1 stop

$249American Airlines

Find Deal

Sat, Nov 15 - Sat, Nov 22

6:15 am - 2:50 pmDSM-MEM

8h 35m2 stops

3:00 pm - 9:35 pmMEM-DSM

6h 35m2 stops

$304Southwest

Find Deal

Mon, Nov 17 - Thu, Nov 20

6:30 am - 6:08 pmDSM-MEM

11h 38m2 stops

8:10 pm - 1:52 pmMEM-DSM

17h 42m1 stop

$311Multiple Airlines

Find Deal

Sun, Oct 5 - Thu, Oct 9

8:59 pm - 5:58 pmOMA-MEM

20h 59m2 stops

8:10 pm - 8:04 pmMEM-OMA

23h 54m1 stop

$312Multiple Airlines

Find Deal

Sat, Oct 18 - Sun, Oct 19

3:25 pm - 9:48 pmDSM-MEM

6h 23m1 stop

9:00 am - 2:11 pmMEM-DSM

5h 11m1 stop

$327United Airlines

Find Deal

Fri, Oct 24 - Sun, Oct 26

8:30 am - 6:56 pmMLI-MOB

10h 26m2 stops

1:01 pm - 8:58 pmMOB-MLI

7h 57m2 stops

$329United Airlines

Find Deal

Sat, Feb 21 - Wed, Feb 25

6:50 pm - 11:25 pmOMA-MEM

4h 35m1 stop

2:20 pm - 11:05 pmMEM-OMA

8h 45m2 stops

$388Southwest

Find Deal

Thu, Nov 6 - Mon, Nov 10

Southwest flights from Iowa to Mississippi

Our best Southwest deals on Iowa to Mississippi flight tickets

Southwest

Nov 17

DSM6:15 amDes Moines

8h 35m

2 stops

MEM2:50 pmMemphis

Nov 20

MEM3:00 pmMemphis

6h 35m

2 stops

DSM9:35 pmDes Moines

$304

Find similar

Southwest

Nov 6

OMA6:50 pmOmaha Eppley Airfield

4h 35m

1 stop

MEM11:25 pmMemphis

Nov 10

MEM2:20 pmMemphis

8h 45m

2 stops

OMA11:05 pmOmaha Eppley Airfield

$388

Find similar

Southwest

Nov 26

OMA7:55 pmOmaha Eppley Airfield

4h 10m

1 stop

MEM12:05 amMemphis

Nov 29

MEM5:00 amMemphis

6h 25m

1 stop

OMA11:25 amOmaha Eppley Airfield

$403

Find similar

United Airlines flights from Iowa to Mississippi

Our best United Airlines deals on Iowa to Mississippi flight tickets

United Airlines

Oct 24

DSM3:25 pmDes Moines

6h 23m

1 stop

MEM9:48 pmMemphis

Oct 26

MEM9:00 amMemphis

5h 11m

1 stop

DSM2:11 pmDes Moines

$327

Find similar

United Airlines

Feb 21

MLI8:30 amMoline Quad-City

10h 26m

2 stops

MOB6:56 pmMobile

Feb 25

MOB1:01 pmMobile

7h 57m

2 stops

MLI8:58 pmMoline Quad-City

$329

Find similar

United Airlines

Oct 17

OMA3:17 pmOmaha Eppley Airfield

6h 31m

1 stop

MEM9:48 pmMemphis

Oct 20

MEM10:57 amMemphis

6h 37m

1 stop

OMA5:34 pmOmaha Eppley Airfield

$342

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sun 10/5

2:25 pm-5:27 pm

1 stop27h 02m

Memphis

Thu 10/9

8:10 pm-1:52 pm

1 stop17h 42m

$185

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sat 10/18

5:15 pm-10:48 pm

1 stop5h 33m

Mobile

Tue 10/21

3:45 pm-10:30 pm

1 stop6h 45m

$249

OmahaMobile

OMA - MOB

OMAMOB

Omaha Eppley Airfield

Sat 10/18

11:38 am-5:51 pm

1 stop6h 13m

Mobile

Sat 10/25

6:27 pm-12:37 am

1 stop6h 10m

$249

Cedar RapidsGulfport

CID - GPT

CIDGPT

Cedar Rapids

Sat 11/15

5:55 pm-11:08 pm

1 stop5h 13m

Gulfport Biloxi Regional

Sat 11/22

4:54 pm-11:59 pm

1 stop7h 05m

$249

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Mon 11/17

6:15 am-2:50 pm

2 stops8h 35m

Memphis

Thu 11/20

3:00 pm-9:35 pm

2 stops6h 35m

$304

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sun 10/5

6:30 am-6:08 pm

2 stops11h 38m

Memphis

Thu 10/9

8:10 pm-1:52 pm

1 stop17h 42m

$311

OmahaMemphis

OMA - MEM

OMAMEM

Omaha Eppley Airfield

Sat 10/18

8:59 pm-5:58 pm

2 stops20h 59m

Memphis

Sun 10/19

8:10 pm-8:04 pm

1 stop23h 54m

$312

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 10/24

3:25 pm-9:48 pm

1 stop6h 23m

Memphis

Sun 10/26

9:00 am-2:11 pm

1 stop5h 11m

$327

MolineMobile

MLI - MOB

MLIMOB

Moline Quad-City

Sat 2/21

8:30 am-6:56 pm

2 stops10h 26m

Mobile

Wed 2/25

1:01 pm-8:58 pm

2 stops7h 57m

$329

OmahaMemphis

OMA - MEM

OMAMEM

Omaha Eppley Airfield

Thu 11/6

6:50 pm-11:25 pm

1 stop4h 35m

Memphis

Mon 11/10

2:20 pm-11:05 pm

2 stops8h 45m

$388

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Iowa to Mississippi

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Mississippi?

The cheapest day to depart from Iowa to Mississippi is on a Saturday. Travelers who choose to depart for Mississippi on a Saturday will often find tickets for as low as $296. Flights from Iowa to Mississippi on a Wednesday will generally be more expensive and average around $508. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Mississippi?

According to our data, the cheapest time of day to fly to Mississippi is in the afternoon. momondo users have found flights departing from Iowa to Mississippi in the afternoon for as low as $296. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. At noon is when there is more demand to fly to Mississippi, so prices are often more expensive at around $560 per ticket.

Can stopping save me money on Iowa to Mississippi flights?

You could potentially save up to 15% on your flight if you consider stops on a Iowa to Mississippi flight.

Cheap Iowa to Mississippi flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Mississippi

Direct flights	None

There are no direct flights from Iowa to Mississippi. There are no popular flight routes from Iowa to Mississippi.

Search flight deals

When did momondo last update prices for flights from Iowa to Mississippi?
Prices for flights from Iowa to Mississippi are updated daily.
How many operators does momondo search for flights from Iowa to Mississippi?
As of September 2025, there are 4 operators available to choose from for flights from Iowa to Mississippi.
How old do you have to be to fly from Iowa to Mississippi?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Iowa to Mississippi.
What documentation or ID do you need to fly to Mississippi?
The travel and health documents required for your trip to Mississippi can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Mississippi. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Iowa to Mississippi

Compare and see reviews for airlines that fly from Iowa to Mississippi with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.2 10,000 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Mississippi?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Iowa to Mississippi. momondo saves you time and could save you money on your trip.

Can I find flights from Iowa to Mississippi with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Iowa to Mississippi flights to just show those with flexible booking policies.

How can momondo help me find flights from Iowa to Mississippi?

Once you have performed a search for Iowa to Mississippi flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Iowa to Mississippi right now. Can momondo alert me if prices change?

Price alerts on flights to Mississippi from Iowa are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.