Cheap flights from Indianapolis to San Francisco Bay Area from $138

In general, September is the cheapest month to fly from Indianapolis to San Francisco Bay Area. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $336. If you aren’t able to travel to San Francisco Bay Area during the month of September, then flying in May is also cheap. Prices for this month can be found on momondo for an average of $359.

On average, the least expensive day to fly to San Francisco Bay Area from Indianapolis is on a Friday. momondo users have found tickets for Friday departures for as low as $457. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Monday is the most expensive day to depart from Indianapolis because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $765.

Our most recent data shows that the best time of day to fly to San Francisco Bay Area is in the morning. Flights from Indianapolis to San Francisco Bay Area during this time can be as low as $510. In contrast, the most expensive time of day to depart to San Francisco Bay Area is in the evening when prices are around $1,026.

Fly from Indianapolis to San Francisco for the best Indianapolis - San Francisco Bay Area flight prices

You are more likely to see cheaper flights to San Francisco Bay Area from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco Bay Area for around $382 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco Bay Area from Indianapolis for as low as $293 on momondo.

There are 4 cabin classes available to choose from on Indianapolis to San Francisco Bay Area flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier, Delta, and Southwest are the most popular carriers operating from Indianapolis to San Francisco Bay Area

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to San Francisco Bay Area from Indianapolis according to our data. United Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to San Francisco Bay Area. Keep in mind that there are 7 different airlines that fly to San Francisco Bay Area on a routine basis, so you have a few additional options to choose from.

As of April 2026, 4 flights take off from Indianapolis and land in San Francisco Bay Area each day. The most common flight departure time for this route is 7:00PM, with 55% of daily flights taking off in the evening.

As of April 2026, there are 28 flights per week flying from Indianapolis to San Francisco Bay Area. The most common day of the week flights depart is Sun, with 25% of flights taking off on this day.