How many flights depart from Indiana to South Carolina on average per day?

85 flights are operational daily from Indiana to South Carolina as of July 2025. The most popular departure time for this route is 5:00PM, with 80% of flights per day taking off in the afternoon.

What is the cheapest airline that flies from Indiana to South Carolina?

Frontier, Spirit Airlines, and Allegiant Air are the most popular carriers operating from Indiana to South Carolina

How many flights depart from Indiana to South Carolina on average per week?

As of July 2025, 598 flights take off from Indiana and land in South Carolina each week. The most common flight departure day for this route is Thu, with 21% of weekly flights taking off on this day.

What airlines fly to South Carolina?

American Airlines, Delta and Allegiant Air are the top three most popular airlines that fly to South Carolina from Indiana according to our data. American Airlines is the first choice among our users, with 54% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 6 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How long is the flight from Indiana to South Carolina?

Flight times vary depending on what airport in Indiana you fly out of and what airport in South Carolina you fly into. For example, flying from Indianapolis to Charleston takes 1h 44m on average. On the other hand, flying from Evansville to Charleston takes 3h 24m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

When did momondo last update prices for flights from Indiana to South Carolina?

Prices for flights from Indiana to South Carolina are updated daily.

How many operators does momondo search for flights from Indiana to South Carolina?

As of July 2025, there are 8 operators available to choose from for flights from Indiana to South Carolina.

How old do you have to be to fly from Indiana to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indiana to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$35 Cheap Flights from Indiana to South Carolina in 2025

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Indiana to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

1:08 pm - 4:16 pmORD-CLT

2h 08mnonstop

8:49 pm - 10:07 pmCLT-ORD

2h 18mnonstop

$59Frontier

Find Deal

jue., oct. 23 - lun., oct. 27

10:15 am - 11:47 amCVG-MYR

1h 32mnonstop

6:19 pm - 8:00 pmMYR-CVG

1h 41mnonstop

$68Allegiant Air

Find Deal

sáb., ago. 23 - sáb., ago. 30

10:12 am - 1:13 pmORD-MYR

2h 01mnonstop

2:18 pm - 3:43 pmMYR-ORD

2h 25mnonstop

$98Spirit Airlines

Find Deal

jue., ago. 28 - dom., ago. 31

9:51 am - 1:04 pmORD-CLT

2h 13mnonstop

4:17 pm - 5:30 pmCLT-ORD

2h 13mnonstop

$134American Airlines

Find Deal

sáb., sep. 6 - sáb., sep. 6

10:12 am - 1:13 pmORD-MYR

2h 01mnonstop

2:40 pm - 11:59 pmMYR-ORD

10h 19m1 stop

$135Spirit Airlines

Find Deal

dom., ago. 24 - mar., ago. 26

5:00 am - 8:02 amORD-CLT

2h 02mnonstop

9:25 am - 10:42 amCLT-ORD

2h 17mnonstop

$138American Airlines

Find Deal

jue., nov. 6 - jue., nov. 6

6:16 pm - 9:37 pmORD-CLT

2h 21mnonstop

6:40 am - 8:00 amCLT-ORD

2h 20mnonstop

$141United Airlines

Find Deal

vie., ago. 29 - mar., sep. 2

7:10 am - 10:26 amORD-CLT

2h 16mnonstop

6:40 am - 8:00 amCLT-ORD

2h 20mnonstop

$143United Airlines

Find Deal

jue., ago. 28 - lun., sep. 1

6:46 pm - 11:49 pmCVG-MYR

5h 03m1 stop

2:20 pm - 8:01 pmMYR-CVG

5h 41m1 stop

$197Delta

Find Deal

jue., ago. 21 - lun., ago. 25

6:00 am - 1:02 pmMDW-CLT

6h 02m1 stop

5:30 am - 9:40 amCLT-MDW

5h 10m1 stop

$197Delta

Find Deal

vie., sep. 12 - dom., sep. 14

Frontier flights from Indiana to South Carolina

Our best Frontier deals on Indiana to South Carolina flight tickets

Frontier

Oct 23

ORD1:08 pmChicago O'Hare Intl

2h 08m

CLT4:16 pmCharlotte Douglas

Oct 27

CLT8:49 pmCharlotte Douglas

2h 18m

ORD10:07 pmChicago O'Hare Intl

$59

Find similar

Frontier

Oct 17

ORD1:08 pmChicago O'Hare Intl

2h 08m

CLT4:16 pmCharlotte Douglas

Oct 20

CLT8:49 pmCharlotte Douglas

2h 18m

ORD10:07 pmChicago O'Hare Intl

$74

Find similar

Frontier

Oct 9

ORD1:08 pmChicago O'Hare Intl

2h 08m

CLT4:16 pmCharlotte Douglas

Oct 12

CLT8:49 pmCharlotte Douglas

2h 18m

ORD10:07 pmChicago O'Hare Intl

$99

Find similar

Southwest flights from Indiana to South Carolina

Our best Southwest deals on Indiana to South Carolina flight tickets

Southwest

Oct 14

MDW6:00 pmChicago Midway

1h 50m

CLT8:50 pmCharlotte Douglas

Oct 18

CLT6:30 amCharlotte Douglas

1h 55m

MDW7:25 amChicago Midway

$139

Find similar

Southwest

Sep 6

MDW5:35 pmChicago Midway

1h 55m

CLT8:30 pmCharlotte Douglas

Sep 7

CLT6:00 amCharlotte Douglas

1h 55m

MDW6:55 amChicago Midway

$141

Find similar

Southwest

Sep 12

MDW6:45 pmChicago Midway

1h 55m

CLT9:40 pmCharlotte Douglas

Sep 14

CLT6:00 amCharlotte Douglas

1h 55m

MDW6:55 amChicago Midway

$143

Find similar

Fly from

Fly to

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

jue. 10/23

1:08 pm-4:16 pm

Nonstop2h 08m

Charlotte Douglas

lun. 10/27

8:49 pm-10:07 pm

Nonstop2h 18m

$59

CincinnatiMyrtle Beach

CVG - MYR

CVGMYR

Cincinnati Cinci./N. Kentucky

sáb. 8/23

10:15 am-11:47 am

Nonstop1h 32m

Myrtle Beach Intl

sáb. 8/30

6:19 pm-8:00 pm

Nonstop1h 41m

$68

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

jue. 8/28

10:12 am-1:13 pm

Nonstop2h 01m

Myrtle Beach Intl

dom. 8/31

2:18 pm-3:43 pm

Nonstop2h 25m

$98

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

sáb. 9/6

9:51 am-1:04 pm

Nonstop2h 13m

Charlotte Douglas

sáb. 9/6

4:17 pm-5:30 pm

Nonstop2h 13m

$134

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

dom. 8/24

10:12 am-1:13 pm

Nonstop2h 01m

Myrtle Beach Intl

mar. 8/26

2:40 pm-11:59 pm

1 stop10h 19m

$135

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

jue. 11/6

5:00 am-8:02 am

Nonstop2h 02m

Charlotte Douglas

jue. 11/6

9:25 am-10:42 am

Nonstop2h 17m

$138

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

vie. 8/29

6:16 pm-9:37 pm

Nonstop2h 21m

Charlotte Douglas

mar. 9/2

6:40 am-8:00 am

Nonstop2h 20m

$141

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

jue. 8/28

7:10 am-10:26 am

Nonstop2h 16m

Charlotte Douglas

lun. 9/1

6:40 am-8:00 am

Nonstop2h 20m

$143

CincinnatiMyrtle Beach

CVG - MYR

CVGMYR

Cincinnati Cinci./N. Kentucky

jue. 8/21

6:46 pm-11:49 pm

1 stop5h 03m

Myrtle Beach Intl

lun. 8/25

2:20 pm-8:01 pm

1 stop5h 41m

$197

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

vie. 9/12

6:00 am-1:02 pm

1 stop6h 02m

Charlotte Douglas

dom. 9/14

5:30 am-9:40 am

1 stop5h 10m

$197

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indiana to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Indiana is in June. Flight prices, which tend to average around $165, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of June, then book flights to South Carolina from Indiana during July instead. Flights to South Carolina in July, while not as cheap as those in June, still average around $199.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $45. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $372.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Indiana to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $138. Try not to purchase tickets in the evening because they tend to be around $326. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Indiana to South Carolina flight route?

Fly from Indianapolis to Myrtle Beach Intl for the best Indiana - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Indiana when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $317 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Indiana for as low as $201 on momondo.

What cabin class options are available on Indiana to South Carolina flights?

There are 1 cabin classes available to choose from on Indiana to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Indiana to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Indiana to South Carolina.

Cheap Indiana to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to South Carolina

Best Price Found	$35
Fastest flight time	1h 29m
Direct flights	Every day
Airports in South Carolina	4 airports

The best one-way flight to South Carolina from Indiana in the past 72 hours is $35. The best round-trip flight deal from Indiana to South Carolina found on momondo in the last 72 hours is $59.

The fastest flight from Indiana to South Carolina takes 1h 29m

Direct flights go from Indiana to South Carolina every day.

There are 4 airports near South Carolina: Greenville (GSP), Myrtle Beach Intl (MYR), Charlotte Douglas (CLT), Charleston (CHS)

Search flight deals

When did momondo last update prices for flights from Indiana to South Carolina?
Prices for flights from Indiana to South Carolina are updated daily.
How many operators does momondo search for flights from Indiana to South Carolina?
As of July 2025, there are 8 operators available to choose from for flights from Indiana to South Carolina.
How old do you have to be to fly from Indiana to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indiana to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Indiana to South Carolina?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Indiana to South Carolina is Airbus A320-100/200 (88.48% of total bookings). The next most popular plane models are Airbus A319 (2.12%), Airbus A321neo (1.52%), and Boeing 737-800 (1.21%).

Best airlines flying from Indiana to South Carolina

Compare and see reviews for airlines that fly from Indiana to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $76	Free Cancellation	Rating 7.2 702 reviews	Search Allegiant Air flights
Spirit Airlines	PriceFrom $134	Free Cancellation	Rating 6.3 8,049 reviews	Search Spirit Airlines flights
Delta	PriceFrom $197	Free Cancellation	Rating 8.0 7,981 reviews	Search Delta flights
American Airlines	PriceFrom $198	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
United Airlines	PriceFrom $198	Free Cancellation	Rating 7.4 8,900 reviews	Search United Airlines flights
Southwest	PriceFrom $247	Free Cancellation	Rating 8.0 4,246 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Indiana to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Indiana to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Indiana to South Carolina with flexible booking policies on momondo?

Flights from Indiana to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Indiana to South Carolina?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Indiana to South Carolina.

I’m not ready to book a flight from Indiana to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Indiana and alert you when they change.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

mar. 8/5

mar. 8/12

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Flights to New Yorkfrom $39

Flights to Los Angelesfrom $37

Flights to Miamifrom $58

Flights to Chicagofrom $59

Flights to Orlandofrom $54

Flights to Las Vegasfrom $35

Flights to San Franciscofrom $49

Flights to Washington, D.C.from $49

Flights to Bostonfrom $77

Flights to Atlantafrom $29

Flights to Dallasfrom $55

Flights to Seattlefrom $93

Cheap flights from Indiana to South Carolina from $35

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indiana to South Carolina departing on 10/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Indiana to South Carolina

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

Frontier flights from Indiana to South Carolina

Our best Frontier deals on Indiana to South Carolina flight tickets

Southwest flights from Indiana to South Carolina

Our best Southwest deals on Indiana to South Carolina flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Indiana to South Carolina that are best for you.

See travel insights to South Carolina from

How to get the cheapest flight ticket from Indiana to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $45. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $372.

What is the cheapest time of day to depart on your flight to South Carolina?

What is the cheapest Indiana to South Carolina flight route?

Fly from Indianapolis to Myrtle Beach Intl for the best Indiana - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

What cabin class options are available on Indiana to South Carolina flights?

There are 1 cabin classes available to choose from on Indiana to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Indiana to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Indiana to South Carolina.

What is the cheapest airline that flies from Indiana to South Carolina?

Frontier, Spirit Airlines, and Allegiant Air are the most popular carriers operating from Indiana to South Carolina

What airlines fly to South Carolina?

How many flights depart from Indiana to South Carolina on average per day?

85 flights are operational daily from Indiana to South Carolina as of July 2025. The most popular departure time for this route is 5:00PM, with 80% of flights per day taking off in the afternoon.

How many flights depart from Indiana to South Carolina on average per week?

As of July 2025, 598 flights take off from Indiana and land in South Carolina each week. The most common flight departure day for this route is Thu, with 21% of weekly flights taking off on this day.

How long is the flight from Indiana to South Carolina?

Cheap Indiana to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to South Carolina

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

When did momondo last update prices for flights from Indiana to South Carolina?

How many operators does momondo search for flights from Indiana to South Carolina?

How old do you have to be to fly from Indiana to South Carolina?

What documentation or ID do you need to fly to South Carolina?

What is the most popular plane model from Indiana to South Carolina?

Best airlines flying from Indiana to South Carolina

Compare and see reviews for airlines that fly from Indiana to South Carolina with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Indiana to South Carolina?

Can I find flights from Indiana to South Carolina with flexible booking policies on momondo?

How can momondo help me find flights from Indiana to South Carolina?

I’m not ready to book a flight from Indiana to South Carolina right now. Can momondo alert me if prices change?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo