What is the cheapest airline that flies from Indiana to South Carolina?

Allegiant Air, Spirit Airlines, and Frontier are the most popular carriers operating from Indiana to South Carolina

How many flights depart from Indiana to South Carolina on average per week?

As of December 2025, 573 flights take off from Indiana and land in South Carolina each week. The most common flight departure day for this route is Sun, with 20% of weekly flights taking off on this day.

What airlines fly to South Carolina?

American Airlines, Delta and Allegiant Air are the top three most popular airlines that fly to South Carolina from Indiana according to our data. American Airlines is the first choice among our users, with 51% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 6 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How long is the flight from Indiana to South Carolina?

Flight times vary depending on what airport in Indiana you fly out of and what airport in South Carolina you fly into. For example, flying from Indianapolis to Charleston takes 3h 43m on average. On the other hand, flying from Fort Wayne to Charleston takes 3h 59m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

When did momondo last update prices for flights from Indiana to South Carolina?

Prices for flights from Indiana to South Carolina are updated daily.

How many operators does momondo search for flights from Indiana to South Carolina?

As of December 2025, there are 8 operators available to choose from for flights from Indiana to South Carolina.

How old do you have to be to fly from Indiana to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indiana to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$30 Cheap Flights from Indiana to South Carolina in 2025/26

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Find the cheapest flights from Indiana to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:19 pm - 7:25 pm

ORD

CLT

2h 06mnonstop

8:20 pm - 9:42 pm

CLT

ORD

2h 22mnonstop

$63Frontier

Thu, Feb 5 - Mon, Feb 9

11:53 am - 3:00 pm

ORD

CLT

2h 07mnonstop

3:45 pm - 5:07 pm

CLT

ORD

2h 22mnonstop

$66Frontier

Thu, Jan 8 - Mon, Jan 12

7:31 pm - 9:08 pm

CVG

SAV

1h 37mnonstop

4:50 pm - 6:41 pm

SAV

CVG

1h 51mnonstop

$78Allegiant Air

Thu, Jan 8 - Sun, Jan 25

7:31 pm - 9:08 pm

CVG

SAV

1h 37mnonstop

4:50 pm - 6:41 pm

SAV

CVG

1h 51mnonstop

$103Allegiant Air

Thu, Jan 22 - Sun, Jan 25

1:55 pm - 4:52 pm

ORD

GSP

1h 57mnonstop

10:51 am - 12:10 pm

GSP

ORD

2h 19mnonstop

$202United Airlines

Wed, Jan 14 - Sun, Jan 18

2:06 pm - 5:01 pm

ORD

GSP

1h 55mnonstop

10:00 am - 2:25 pm

GSP

ORD

5h 25m1 stop

$205United Airlines

Thu, Jan 1 - Wed, Jan 14

5:30 am - 11:58 am

ORD

GSP

5h 28m1 stop

11:30 am - 6:28 pm

GSP

ORD

7h 58m1 stop

$215Delta

Thu, Jan 1 - Wed, Jan 14

11:25 am - 4:53 pm

ORD

GSP

4h 28m1 stop

6:50 am - 10:07 am

GSP

ORD

4h 17m1 stop

$216Delta

Sat, Jan 17 - Sun, Jan 18

5:50 pm - 11:41 pm

ORD

SAV

4h 51m1 stop

3:45 pm - 5:22 pm

SAV

ORD

2h 37mnonstop

$292American Airlines

Sat, Jan 17 - Sun, Jan 18

1:35 pm - 6:40 pm

ORD

SAV

4h 05m1 stop

3:45 pm - 5:22 pm

SAV

ORD

2h 37mnonstop

$293American Airlines

Sat, Jan 17 - Sun, Jan 18

Frontier flights from Indiana to South Carolina

Our best Frontier deals on Indiana to South Carolina flight tickets

Frontier

Feb 5

ORD4:19 pmChicago O'Hare Intl

2h 06m

CLT7:25 pmCharlotte Douglas

Feb 9

CLT8:20 pmCharlotte Douglas

2h 22m

ORD9:42 pmChicago O'Hare Intl

$63

Find similar

Frontier

Jan 8

ORD11:53 amChicago O'Hare Intl

2h 07m

CLT3:00 pmCharlotte Douglas

Jan 12

CLT3:45 pmCharlotte Douglas

2h 22m

ORD5:07 pmChicago O'Hare Intl

$66

Find similar

Frontier

Jan 8

ORD11:53 amChicago O'Hare Intl

2h 07m

CLT3:00 pmCharlotte Douglas

Jan 12

CLT3:45 pmCharlotte Douglas

2h 22m

ORD5:07 pmChicago O'Hare Intl

$67

Find similar

Spirit Airlines flights from Indiana to South Carolina

Our best Spirit Airlines deals on Indiana to South Carolina flight tickets

Spirit Airlines

Jan 9

ORD5:15 amChicago O'Hare Intl

12h 33m

1 stop

CLT6:48 pmCharlotte Douglas

Jan 15

CLT1:24 pmCharlotte Douglas

8h 39m

1 stop

ORD9:03 pmChicago O'Hare Intl

$132

Find similar

Spirit Airlines

Jan 6

ORD7:30 amChicago O'Hare Intl

9h 38m

1 stop

MYR6:08 pmMyrtle Beach Intl

Jan 17

MYR10:00 amMyrtle Beach Intl

13h 42m

1 stop

ORD10:42 pmChicago O'Hare Intl

$170

Find similar

Spirit Airlines

Jan 20

ORD5:53 pmChicago O'Hare Intl

19h 49m

1 stop

MYR2:42 pmMyrtle Beach Intl

Jan 21

MYR9:59 pmMyrtle Beach Intl

12h 13m

1 stop

ORD9:12 amChicago O'Hare Intl

$171

Find similar

Fly from

Fly to

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 2/5

4:19 pm-7:25 pm

Nonstop2h 06m

Charlotte Douglas

Mon 2/9

8:20 pm-9:42 pm

Nonstop2h 22m

$63

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 1/8

11:53 am-3:00 pm

Nonstop2h 07m

Charlotte Douglas

Mon 1/12

3:45 pm-5:07 pm

Nonstop2h 22m

$66

CincinnatiSavannah

CVG - SAV

CVGSAV

Cincinnati Cinci./N. Kentucky

Thu 1/8

7:31 pm-9:08 pm

Nonstop1h 37m

Savannah/Hilton Head

Sun 1/25

4:50 pm-6:41 pm

Nonstop1h 51m

$78

CincinnatiSavannah

CVG - SAV

CVGSAV

Cincinnati Cinci./N. Kentucky

Thu 1/22

7:31 pm-9:08 pm

Nonstop1h 37m

Savannah/Hilton Head

Sun 1/25

4:50 pm-6:41 pm

Nonstop1h 51m

$103

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 1/14

1:55 pm-4:52 pm

Nonstop1h 57m

Greenville

Sun 1/18

10:51 am-12:10 pm

Nonstop2h 19m

$202

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 1/1

2:06 pm-5:01 pm

Nonstop1h 55m

Greenville

Wed 1/14

10:00 am-2:25 pm

1 stop5h 25m

$205

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 1/1

5:30 am-11:58 am

1 stop5h 28m

Greenville

Wed 1/14

11:30 am-6:28 pm

1 stop7h 58m

$215

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 1/17

11:25 am-4:53 pm

1 stop4h 28m

Greenville

Sun 1/18

6:50 am-10:07 am

1 stop4h 17m

$216

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

Sat 1/17

5:50 pm-11:41 pm

1 stop4h 51m

Savannah/Hilton Head

Sun 1/18

3:45 pm-5:22 pm

Nonstop2h 37m

$292

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

Sat 1/17

1:35 pm-6:40 pm

1 stop4h 05m

Savannah/Hilton Head

Sun 1/18

3:45 pm-5:22 pm

Nonstop2h 37m

$293

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indiana to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Indiana is in June. Flight prices, which tend to average around $164, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of June, then book flights to South Carolina from Indiana during July instead. Flights to South Carolina in July, while not as cheap as those in June, still average around $224.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $45. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $372.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Indiana to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $141. Try not to purchase tickets in the evening because they tend to be around $326. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Indiana to South Carolina flight route?

Fly from Indianapolis to Charleston for the best Indiana - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Indiana when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $320 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Indiana for as low as $152 on momondo.

What cabin class options are available on Indiana to South Carolina flights?

There is only 1 cabin class available to choose from on Indiana to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Indiana to South Carolina flights?

You could potentially save up to 1% on your flight if you consider stops on a Indiana to South Carolina flight.

Cheap Indiana to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to South Carolina

Best Price Found	$194
Fastest flight time	1h 27m
Direct flights	Mon, Wed, Thu, Fri, Sat and Sun
Airports in South Carolina	57 airports

The best flight deal from Indiana to South Carolina found on momondo in the last 72 hours is $194

The fastest flight from Indiana to South Carolina takes 1h 27m

Direct flights go from Indiana to South Carolina on Monday, Wednesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.

There are 57 airports in South Carolina. From Indiana there are direct flights to Greenville (GSP), Myrtle Beach Intl (MYR), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT).

Search flight deals

When did momondo last update prices for flights from Indiana to South Carolina?
Prices for flights from Indiana to South Carolina are updated daily.
How many operators does momondo search for flights from Indiana to South Carolina?
As of December 2025, there are 8 operators available to choose from for flights from Indiana to South Carolina.
How old do you have to be to fly from Indiana to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indiana to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Indiana to South Carolina?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Indiana to South Carolina is Airbus A320-100/200 (54.55% of total bookings). The next most popular plane models are Airbus A319 (27.27%), Boeing 737 MAX 8 (4.55%), and Embraer 175 (Enhanced Winglets) (4.55%).

Best airlines flying from Indiana to South Carolina

Compare and see reviews for airlines that fly from Indiana to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $76	Free Cancellation	Rating 7.2 700 reviews	Search Allegiant Air flights
Spirit Airlines	PriceFrom $128	Free Cancellation	Rating 6.3 8,185 reviews	Search Spirit Airlines flights
American Airlines	PriceFrom $166	Free Cancellation	Rating 7.2 11,052 reviews	Search American Airlines flights
Delta	PriceFrom $196	Free Cancellation	Rating 7.9 8,008 reviews	Search Delta flights
United Airlines	PriceFrom $198	Free Cancellation	Rating 7.4 9,092 reviews	Search United Airlines flights
Southwest	PriceFrom $247	Free Cancellation	Rating 7.9 4,250 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Indiana to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Indiana to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Indiana to South Carolina with flexible booking policies on momondo?

Flights from Indiana to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Indiana to South Carolina?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Indiana to South Carolina.

I’m not ready to book a flight from Indiana to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Indiana and alert you when they change.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Find better results for your trip to South Carolina

Popular cities in South Carolina

Flights to New Yorkfrom $34

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Flights to Orlandofrom $48

Flights to San Franciscofrom $55

Flights to Las Vegasfrom $48

Flights to Washington, D.C.from $57

Flights to Bostonfrom $52

Flights to Atlantafrom $48

Flights to Dallasfrom $56

Flights to Seattlefrom $58

Cheap flights from Indiana to South Carolina from $30

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indiana to South Carolina departing on 2/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Indiana to South Carolina

Cheap round-trip flights

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Cheap last minute flights

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Frontier flights from Indiana to South Carolina

Our best Frontier deals on Indiana to South Carolina flight tickets

Spirit Airlines flights from Indiana to South Carolina

Our best Spirit Airlines deals on Indiana to South Carolina flight tickets

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Use the filters below to find and compare flights from Indiana to South Carolina that are best for you.

See travel insights to South Carolina from

How to get the cheapest flight ticket from Indiana to South Carolina

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $45. The most expensive day to fly to South Carolina is Sunday, with ticket prices averaging around $372.

What is the cheapest time of day to depart on your flight to South Carolina?

What is the cheapest Indiana to South Carolina flight route?

Fly from Indianapolis to Charleston for the best Indiana - South Carolina flight prices

How far in advance should I book a flight to South Carolina?

What cabin class options are available on Indiana to South Carolina flights?

There is only 1 cabin class available to choose from on Indiana to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Indiana to South Carolina flights?

You could potentially save up to 1% on your flight if you consider stops on a Indiana to South Carolina flight.

What is the cheapest airline that flies from Indiana to South Carolina?

Allegiant Air, Spirit Airlines, and Frontier are the most popular carriers operating from Indiana to South Carolina

What airlines fly to South Carolina?

How many flights depart from Indiana to South Carolina on average per week?

As of December 2025, 573 flights take off from Indiana and land in South Carolina each week. The most common flight departure day for this route is Sun, with 20% of weekly flights taking off on this day.

How long is the flight from Indiana to South Carolina?

Cheap Indiana to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to South Carolina

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

When did momondo last update prices for flights from Indiana to South Carolina?

How many operators does momondo search for flights from Indiana to South Carolina?

How old do you have to be to fly from Indiana to South Carolina?

What documentation or ID do you need to fly to South Carolina?

What is the most popular plane model from Indiana to South Carolina?

Best airlines flying from Indiana to South Carolina

Compare and see reviews for airlines that fly from Indiana to South Carolina with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Indiana to South Carolina?

Can I find flights from Indiana to South Carolina with flexible booking policies on momondo?

How can momondo help me find flights from Indiana to South Carolina?

I’m not ready to book a flight from Indiana to South Carolina right now. Can momondo alert me if prices change?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo