How many flights depart from Indiana to South Carolina on average per week?

As of June 2026, 800 flights take off from Indiana and land in South Carolina each week. The most common flight departure day for this route is Mon, with 18% of weekly flights taking off on this day.

How long is the flight from Indiana to South Carolina?

Flight times vary depending on what airport in Indiana you fly out of and what airport in South Carolina you fly into. For example, flying from Indianapolis to Charleston takes 1h 48m on average. On the other hand, flying from South Bend to Charleston takes 3h 35m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

How many flights depart from Indiana to South Carolina on average per day?

114 flights are operational daily from Indiana to South Carolina as of June 2026. The most popular departure time for this route is 4:00PM, with 100% of flights per day taking off in the afternoon.

What is the cheapest airline that flies from Indiana to South Carolina?

United Airlines, Delta, and Southwest are the most popular carriers operating from Indiana to South Carolina

What airlines fly to South Carolina?

American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to South Carolina from Indiana according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 5 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Indiana to South Carolina?

Prices for flights from Indiana to South Carolina are updated daily.

How many operators does momondo search for flights from Indiana to South Carolina?

As of June 2026, there are 8 operators available to choose from for flights from Indiana to South Carolina.

How old do you have to be to fly from Indiana to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indiana to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$72 Cheap Flights from Indiana to South Carolina in 2026

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Find the cheapest flights from Indiana to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:09 am - 9:07 pm

CVG

CLT

10h 58m

2 stops

6:41 pm - 12:07 pm

CLT

CVG

17h 26m

1 stop

$185Multiple Airlines

Fri, Jul 17 - Wed, Jul 22

10:09 am - 9:07 pm

CVG

CLT

10h 58m

2 stops

6:41 pm - 12:07 pm

CLT

CVG

17h 26m

1 stop

$195Multiple Airlines

Fri, Jul 17 - Wed, Jul 22

8:55 am - 7:30 pm

MDW

CLT

9h 35m

2 stops

6:35 pm - 7:35 pm

CLT

MDW

2h 00mnonstop

$229Southwest

Sat, Jul 4 - Wed, Aug 19

11:45 am - 7:20 pm

MDW

CLT

6h 35m

2 stops

8:30 am - 4:50 pm

CLT

MDW

9h 20m

2 stops

$234Southwest

Sat, Sep 19 - Tue, Sep 22

8:26 am - 1:53 pm

ORD

CLT

4h 27m

1 stop

4:18 pm - 5:38 pm

CLT

ORD

2h 20mnonstop

$241American Airlines

Sat, Sep 26 - Sat, Sep 26

4:30 pm - 11:57 pm

MDW

CLT

6h 27m

1 stop

1:09 pm - 6:33 pm

CLT

MDW

6h 24m

1 stop

$246Delta

Sat, Sep 12 - Mon, Sep 14

3:31 pm - 11:30 pm

ORD

MYR

6h 59m

1 stop

2:18 pm - 6:49 pm

MYR

ORD

5h 31m

1 stop

$254Delta

Tue, Aug 11 - Mon, Aug 17

5:05 am - 11:24 am

ORD

MYR

5h 19m

1 stop

12:04 pm - 1:37 pm

MYR

ORD

2h 33mnonstop

$258American Airlines

Sat, Aug 22 - Tue, Aug 25

11:00 am - 2:19 pm

ORD

MYR

2h 19mnonstop

3:15 pm - 4:49 pm

MYR

ORD

2h 34mnonstop

$261United Airlines

Wed, Jul 8 - Tue, Jul 14

6:55 am - 9:55 am

ORD

GSP

2h 00mnonstop

5:43 pm - 7:00 pm

GSP

ORD

2h 17mnonstop

$262United Airlines

Wed, Jul 1 - Sat, Jul 4

Frontier flights from Indiana to South Carolina

Our best Frontier deals on Indiana to South Carolina flight tickets

Frontier

Jun 30

CVG9:30 pmCincinnati Cinci./N. Kentucky

19h 10m

1 stop

CLT4:40 pmCharlotte Douglas

Jul 7

CLT12:24 pmCharlotte Douglas

24h 34m

1 stop

CVG12:58 pmCincinnati Cinci./N. Kentucky

$230

Frontier

Jul 1

ORD4:59 pmChicago O'Hare Intl

22h 31m

1 stop

CLT4:30 pmCharlotte Douglas

Jul 8

CLT8:28 pmCharlotte Douglas

27h 59m

1 stop

ORD11:27 pmChicago O'Hare Intl

$231

Frontier

Jul 1

ORD4:59 pmChicago O'Hare Intl

17h 35m

1 stop

CLT11:34 amCharlotte Douglas

Jul 8

CLT5:57 pmCharlotte Douglas

7h 52m

1 stop

ORD12:49 amChicago O'Hare Intl

$232

Delta flights from Indiana to South Carolina

Our best Delta deals on Indiana to South Carolina flight tickets

Delta

Sep 12

MDW4:30 pmChicago Midway

6h 27m

1 stop

CLT11:57 pmCharlotte Douglas

Sep 14

CLT1:09 pmCharlotte Douglas

6h 24m

1 stop

MDW6:33 pmChicago Midway

$246

Delta

Aug 11

ORD3:31 pmChicago O'Hare Intl

6h 59m

1 stop

MYR11:30 pmMyrtle Beach Intl

Aug 17

MYR2:18 pmMyrtle Beach Intl

5h 31m

1 stop

ORD6:49 pmChicago O'Hare Intl

$254

Delta

Jun 17

MDW6:00 amChicago Midway

6h 35m

1 stop

CLT1:35 pmCharlotte Douglas

Aug 19

CLT9:49 amCharlotte Douglas

3h 50m

1 stop

MDW12:39 pmChicago Midway

$263

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CincinnatiCharlotte

CVG - CLT

CVGCLT

Cincinnati Cinci./N. Kentucky

Fri 7/17

10:09 am-9:07 pm

2 stops10h 58m

Charlotte Douglas

Wed 7/22

6:41 pm-12:07 pm

1 stop17h 26m

$185

CincinnatiCharlotte

CVG - CLT

CVGCLT

Cincinnati Cinci./N. Kentucky

Fri 7/17

10:09 am-9:07 pm

2 stops10h 58m

Charlotte Douglas

Wed 7/22

6:41 pm-12:07 pm

1 stop17h 26m

$195

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 7/4

8:55 am-7:30 pm

2 stops9h 35m

Charlotte Douglas

Wed 8/19

6:35 pm-7:35 pm

Nonstop2h 00m

$229

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 9/19

11:45 am-7:20 pm

2 stops6h 35m

Charlotte Douglas

Tue 9/22

8:30 am-4:50 pm

2 stops9h 20m

$234

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 9/26

8:26 am-1:53 pm

1 stop4h 27m

Charlotte Douglas

Sat 9/26

4:18 pm-5:38 pm

Nonstop2h 20m

$241

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 9/12

4:30 pm-11:57 pm

1 stop6h 27m

Charlotte Douglas

Mon 9/14

1:09 pm-6:33 pm

1 stop6h 24m

$246

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Tue 8/11

3:31 pm-11:30 pm

1 stop6h 59m

Myrtle Beach Intl

Mon 8/17

2:18 pm-6:49 pm

1 stop5h 31m

$254

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Sat 8/22

5:05 am-11:24 am

1 stop5h 19m

Myrtle Beach Intl

Tue 8/25

12:04 pm-1:37 pm

Nonstop2h 33m

$258

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Wed 7/8

11:00 am-2:19 pm

Nonstop2h 19m

Myrtle Beach Intl

Tue 7/14

3:15 pm-4:49 pm

Nonstop2h 34m

$261

Quickest round-trip

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 7/1

6:55 am-9:55 am

Nonstop2h 00m

Greenville

Sat 7/4

5:43 pm-7:00 pm

Nonstop2h 17m

$262

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indiana to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Indiana is in August. Flight prices, which tend to average around $41, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to South Carolina from Indiana during July instead. Flights to South Carolina in July, while not as cheap as those in August, still average around $48.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Wednesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $45. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $148.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Indiana to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $118. Try not to purchase tickets in the afternoon because they tend to be around $137. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Indiana to South Carolina flight route?

Fly from Indianapolis to Myrtle Beach Intl for the best Indiana - South Carolina flight prices

How far in advance should I book a flight from Indiana to South Carolina?

You are more likely to see cheaper flights to South Carolina from Indiana when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $320 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Indiana for as low as $188 on momondo.

What cabin class options are available on Indiana to South Carolina flights?

There is only 1 cabin class available to choose from on Indiana to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Indiana to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Indiana to South Carolina.

Cheap Indiana to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to South Carolina

Best Price Found	$49
Fastest flight time	1h 17m
Direct flights	Every day
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Indiana in the past 72 hours is $49. The best round-trip flight deal from Indiana to South Carolina found on momondo in the last 72 hours is $90.

The fastest flight from Indiana to South Carolina takes 1h 17m

Direct flights go from Indiana to South Carolina every day.

There are 57 airports in South Carolina. From Indiana there are direct flights to Greenville (GSP), Myrtle Beach Intl (MYR), Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Indiana to South Carolina

When did momondo last update prices for flights from Indiana to South Carolina?
Prices for flights from Indiana to South Carolina are updated daily.
How many operators does momondo search for flights from Indiana to South Carolina?
As of June 2026, there are 8 operators available to choose from for flights from Indiana to South Carolina.
How old do you have to be to fly from Indiana to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indiana to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Indiana to South Carolina?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Indiana to South Carolina is Airbus A320-100/200 (96.10% of total bookings). The next most popular plane models are Boeing 737 MAX 8 (1.46%), Airbus A319 (0.98%), and Embraer 175 (Enhanced Winglets) (0.49%).

Best airlines flying from Indiana to South Carolina

Compare and see reviews for airlines that fly from Indiana to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $50	Free Cancellation	Rating 7.3 707 reviews	Search Allegiant Air flights
Delta	PriceFrom $151	Free Cancellation	Rating 7.9 8,400 reviews	Search Delta flights
American Airlines	PriceFrom $166	Free Cancellation	Rating 7.1 11,644 reviews	Search American Airlines flights
United Airlines	PriceFrom $198	Free Cancellation	Rating 7.4 9,775 reviews	Search United Airlines flights
Southwest	PriceFrom $253	Free Cancellation	Rating 8.0 4,260 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Indiana to South Carolina?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Indiana to South Carolina. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Indiana to South Carolina with flexible booking policies on momondo?

Flights from Indiana to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Indiana to South Carolina?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Indiana to South Carolina.

I’m not ready to book a flight from Indiana to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Indiana and alert you when they change.

An easier way to manage your South Carolina trip

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Popular cities in South Carolina

Flights to New Yorkfrom $64

Flights to Los Angelesfrom $77

Flights to Orlandofrom $58

Flights to Miamifrom $78

Flights to Chicagofrom $68

Flights to San Franciscofrom $66

Flights to Las Vegasfrom $66

Flights to Washington, D.C.from $50

Flights to Bostonfrom $66

Flights to Atlantafrom $81

Flights to Fort Lauderdalefrom $58

Flights to Dallasfrom $56

Cheap flights from Indiana to South Carolina from $84

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indiana to South Carolina departing on 8/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Frontier flights from Indiana to South Carolina

Our best Frontier deals on Indiana to South Carolina flight tickets

Delta flights from Indiana to South Carolina

Our best Delta deals on Indiana to South Carolina flight tickets

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See travel insights to South Carolina from

How to get the cheapest flight ticket from Indiana to South Carolina

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

What is the cheapest time of day to depart on your flight to South Carolina?

What is the cheapest Indiana to South Carolina flight route?

How far in advance should I book a flight from Indiana to South Carolina?

What cabin class options are available on Indiana to South Carolina flights?

Can stopping save me money on Indiana to South Carolina flights?

What is the cheapest airline that flies from Indiana to South Carolina?

What airlines fly to South Carolina?

How many flights depart from Indiana to South Carolina on average per day?

How many flights depart from Indiana to South Carolina on average per week?

How long is the flight from Indiana to South Carolina?

Cheap Indiana to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to South Carolina

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

Frequently asked questions about flying from Indiana to South Carolina

Best airlines flying from Indiana to South Carolina

Compare and see reviews for airlines that fly from Indiana to South Carolina with momondo

Why use momondo?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo

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According to popular flight searches on momondo this year

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