Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Illinois to Des Moines from $102

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Illinois to Des Moines departing on 4/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Illinois to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
3:55 pm - 10:10 pm
STL
-
DSM
6h 15m
1 stop
Southwest Logo
6:30 pm - 11:10 pm
DSM
-
STL
4h 40m
1 stop
$213Southwest
Tue, Apr 14 - Tue, Apr 21
Southwest Logo
5:35 am - 11:25 am
STL
-
DSM
5h 50m
1 stop
Southwest Logo
6:55 am - 1:00 pm
DSM
-
STL
6h 05m
2 stops
$218Southwest
Tue, Apr 14 - Tue, Apr 21
Southwest Logo
1:15 pm - 10:10 pm
STL
-
DSM
8h 55m
2 stops
Southwest Logo
5:30 am - 3:15 pm
DSM
-
STL
9h 45m
2 stops
$223Southwest
Tue, Apr 14 - Tue, Apr 21
Multiple Airlines Logo
1:27 pm - 4:00 pm
ORD
-
DSM
26h 33m
1 stop
Multiple Airlines Logo
2:36 pm - 11:55 pm
DSM
-
ORD
9h 19m
1 stop
$251Multiple Airlines
Wed, Apr 22 - Sun, May 3
Multiple Airlines Logo
12:00 pm - 10:06 pm
ORD
-
DSM
10h 06m
1 stop
Multiple Airlines Logo
8:14 pm - 2:07 pm
DSM
-
ORD
41h 53m
2 stops
$253Multiple Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
10:29 pm - 11:49 pm
ORD
-
DSM
1h 20mnonstop
American Airlines Logo
8:56 am - 10:36 am
DSM
-
ORD
1h 40mnonstop
$280American Airlines
Tue, Apr 21 - Thu, Apr 30
Delta Logo
9:29 am - 3:41 pm
MDW
-
DSM
6h 12m
1 stop
Delta Logo
6:10 am - 12:43 pm
DSM
-
MDW
6h 33m
1 stop
$289Delta
Wed, Apr 15 - Wed, Apr 22
Delta Logo
9:29 am - 3:41 pm
MDW
-
DSM
6h 12m
1 stop
Delta Logo
6:10 am - 12:43 pm
DSM
-
MDW
6h 33m
1 stop
$300Delta
Tue, Apr 21 - Thu, Apr 30
United Airlines Logo
5:35 pm - 9:32 pm
PIA
-
DSM
3h 57m
1 stop
United Airlines Logo
1:10 pm - 6:53 pm
DSM
-
PIA
5h 43m
1 stop
$309United Airlines
Fri, Apr 3 - Tue, Apr 7
United Airlines Logo
5:35 pm - 9:32 pm
PIA
-
DSM
3h 57m
1 stop
United Airlines Logo
1:10 pm - 6:53 pm
DSM
-
PIA
5h 43m
1 stop
$369United Airlines
Sat, Apr 11 - Wed, Apr 15

United Airlines flights from Illinois to Des Moines

Our best United Airlines deals on Illinois to Des Moines flight tickets
United Airlines
Apr 18
ORD9:40 pmChicago O'Hare Intl
1h 37m
DSM11:17 pmDes Moines
Apr 21
DSM3:21 pmDes Moines
1h 32m
ORD4:53 pmChicago O'Hare Intl
$280
United Airlines
Apr 3
PIA5:35 pmGreater Peoria
3h 57m
1 stop
DSM9:32 pmDes Moines
Apr 7
DSM1:10 pmDes Moines
5h 43m
1 stop
PIA6:53 pmGreater Peoria
$309
United Airlines
May 29
ORD2:15 pmChicago O'Hare Intl
1h 33m
DSM3:48 pmDes Moines
May 31
DSM11:18 amDes Moines
1h 40m
ORD12:58 pmChicago O'Hare Intl
$329

Delta flights from Illinois to Des Moines

Our best Delta deals on Illinois to Des Moines flight tickets
Delta
Apr 15
MDW9:29 amChicago Midway
6h 12m
1 stop
DSM3:41 pmDes Moines
Apr 22
DSM6:10 amDes Moines
6h 33m
1 stop
MDW12:43 pmChicago Midway
$289
Delta
Apr 21
MDW9:29 amChicago Midway
6h 12m
1 stop
DSM3:41 pmDes Moines
Apr 30
DSM6:10 amDes Moines
6h 33m
1 stop
MDW12:43 pmChicago Midway
$300
Delta
Apr 13
ORD1:36 pmChicago O'Hare Intl
7h 03m
1 stop
DSM8:39 pmDes Moines
Apr 16
DSM6:10 amDes Moines
4h 09m
1 stop
ORD10:19 amChicago O'Hare Intl
$311

momondo Fare Finder

 
Customize your flight search to find flights from Illinois to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Illinois to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 4/14

3:55 pm-10:10 pm

1 stop6h 15m

Des Moines

Tue 4/21

6:30 pm-11:10 pm

1 stop4h 40m

$213

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 4/14

5:35 am-11:25 am

1 stop5h 50m

Des Moines

Tue 4/21

6:55 am-1:00 pm

2 stops6h 05m

$218

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 4/14

1:15 pm-10:10 pm

2 stops8h 55m

Des Moines

Tue 4/21

5:30 am-3:15 pm

2 stops9h 45m

$223

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Wed 4/22

1:27 pm-4:00 pm

1 stop26h 33m

Des Moines

Sun 5/3

2:36 pm-11:55 pm

1 stop9h 19m

$251

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 4/9

12:00 pm-10:06 pm

1 stop10h 06m

Des Moines

Mon 4/13

8:14 pm-2:07 pm

2 stops41h 53m

$253
Quickest round-trip

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Tue 4/21

10:29 pm-11:49 pm

Nonstop1h 20m

Des Moines

Thu 4/30

8:56 am-10:36 am

Nonstop1h 40m

$280

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 4/15

9:29 am-3:41 pm

1 stop6h 12m

Des Moines

Wed 4/22

6:10 am-12:43 pm

1 stop6h 33m

$289

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Tue 4/21

9:29 am-3:41 pm

1 stop6h 12m

Des Moines

Thu 4/30

6:10 am-12:43 pm

1 stop6h 33m

$300

PeoriaDes Moines

PIA - DSM

PIADSM

Greater Peoria

Fri 4/3

5:35 pm-9:32 pm

1 stop3h 57m

Des Moines

Tue 4/7

1:10 pm-6:53 pm

1 stop5h 43m

$309

PeoriaDes Moines

PIA - DSM

PIADSM

Greater Peoria

Sat 4/11

5:35 pm-9:32 pm

1 stop3h 57m

Des Moines

Wed 4/15

1:10 pm-6:53 pm

1 stop5h 43m

$369

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from Illinois to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in July, then October is your next best option. Flight prices from Illinois to Des Moines during October average around $224.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Illinois to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $224. Flights from Illinois to Des Moines on a Tuesday will generally be more expensive and average around $427. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Illinois to Des Moines at noon for as low as $249. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $318. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Illinois to Des Moines flight route?

Fly from Chicago O'Hare Intl to Des Moines for the best Illinois - Des Moines flight prices

What cabin class options are available on Illinois to Des Moines flights?

There are 4 cabin classes available to choose from on Illinois to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Illinois to Des Moines flights?

You could potentially save up to 13% on your flight if you consider stops on a Illinois to Des Moines flight.

Cheap Illinois to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Illinois to Des Moines

Best Price Found

$138

Fastest flight time

1h 20m

Direct flights

Every day

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Illinois in the past 72 hours is $138. The best round-trip flight deal from Illinois to Des Moines found on momondo in the last 72 hours is $237.
The fastest flight from Illinois to Des Moines takes 1h 20m
Direct flights go from Illinois to Des Moines every day.
There is 1 airport in Des Moines. From Illinois there are direct flights to Des Moines (DSM).
Search flight deals

  • When did momondo last update prices for flights from Illinois to Des Moines Airport?

    Prices for flights from Illinois to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Illinois to Des Moines Airport?

  • How old do you have to be to fly from Illinois to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Illinois to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Illinois to Des Moines?

Best airlines flying from Illinois to Des Moines

Compare and see reviews for airlines that fly from Illinois to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $189Free CancellationRating
7.1
11,489 reviews
Search American Airlines flights
United AirlinesPriceFrom $189Free CancellationRating
7.4
9,460 reviews
Search United Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Illinois to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Illinois to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Illinois to Des Moines with flexible booking policies on momondo?

Flights from Illinois to Des Moines with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Illinois to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Illinois. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Illinois to Des Moines right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Des Moines from Illinois. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 4/22
Wed 4/29
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States