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Cheap flights from Illinois to Des Moines from $80

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Illinois to Des Moines departing on 9/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Illinois to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
6:00 pm - 7:30 pmMDW  Chicago Midway-DSM Des Moines
1h 30mnonstop
Southwest Logo
5:40 am - 7:00 amDSM  Des Moines-MDW Chicago Midway
1h 20mnonstop
$206Southwest
Sat, Sep 5 - Mon, Sep 7
Southwest Logo
8:50 pm - 10:15 pmMDW  Chicago Midway-DSM Des Moines
1h 25mnonstop
Southwest Logo
5:40 am - 7:00 amDSM  Des Moines-MDW Chicago Midway
1h 20mnonstop
$206Southwest
Fri, Sep 11 - Mon, Sep 14
Southwest Logo
10:05 am - 11:25 amMDW  Chicago Midway-DSM Des Moines
1h 20mnonstop
Southwest Logo
5:40 am - 7:00 amDSM  Des Moines-MDW Chicago Midway
1h 20mnonstop
$206Southwest
Fri, Sep 11 - Mon, Sep 14
United Airlines Logo
9:00 am - 10:30 amORD  Chicago O'Hare Intl-DSM Des Moines
1h 30mnonstop
United Airlines Logo
1:26 pm - 3:00 pmDSM  Des Moines-ORD Chicago O'Hare Intl
1h 34mnonstop
$215United Airlines
Thu, Sep 24 - Sat, Sep 26
United Airlines Logo
4:00 pm - 5:28 pmORD  Chicago O'Hare Intl-DSM Des Moines
1h 28mnonstop
United Airlines Logo
11:32 am - 1:15 pmDSM  Des Moines-ORD Chicago O'Hare Intl
1h 43mnonstop
$215United Airlines
Tue, Sep 8 - Thu, Sep 10
American Airlines Logo
6:59 am - 8:39 amORD  Chicago O'Hare Intl-DSM Des Moines
1h 40mnonstop
American Airlines Logo
2:29 pm - 4:15 pmDSM  Des Moines-ORD Chicago O'Hare Intl
1h 46mnonstop
$215American Airlines
Mon, Sep 28 - Wed, Sep 30
American Airlines Logo
10:45 pm - 12:20 amORD  Chicago O'Hare Intl-DSM Des Moines
1h 35mnonstop
American Airlines Logo
5:56 pm - 7:59 pmDSM  Des Moines-ORD Chicago O'Hare Intl
2h 03mnonstop
$215American Airlines
Mon, Sep 7 - Thu, Sep 10
United Airlines Logo
8:00 pm - 9:28 pmORD  Chicago O'Hare Intl-DSM Des Moines
1h 28mnonstop
United Airlines Logo
11:32 am - 1:15 pmDSM  Des Moines-ORD Chicago O'Hare Intl
1h 43mnonstop
$215United Airlines
Mon, Sep 21 - Wed, Sep 23
Multiple Airlines Logo
7:25 am - 7:57 pmORD  Chicago O'Hare Intl-DSM Des Moines
12h 32m1 stop Philadelphia
Multiple Airlines Logo
1:58 pm - 1:30 pmDSM  Des Moines-ORD Chicago O'Hare Intl
23h 32m1 stop Philadelphia
$219Multiple Airlines
Thu, Sep 17 - Sun, Sep 20
Multiple Airlines Logo
7:25 am - 7:57 pmORD  Chicago O'Hare Intl-DSM Des Moines
12h 32m1 stop Philadelphia
Multiple Airlines Logo
11:29 am - 12:23 amDSM  Des Moines-ORD Chicago O'Hare Intl
12h 54m1 stop Denver Intl
$228Multiple Airlines
Thu, Sep 10 - Thu, Sep 17

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Frontier flights from Illinois to Des Moines

Our best Frontier deals on Illinois to Des Moines flight tickets
Frontier
Sep 11
ORD6:30 amChicago O'Hare Intl
13h 03m
1 stop
DSM7:33 pmDes Moines
Sep 14
DSM8:30 pmDes Moines
27h 53m
1 stop
ORD12:23 amChicago O'Hare Intl
$252
Frontier
Sep 10
ORD2:46 pmChicago O'Hare Intl
28h 47m
2 stops
DSM7:33 pmDes Moines
Sep 17
DSM11:29 amDes Moines
12h 54m
1 stop
ORD12:23 amChicago O'Hare Intl
$262
Frontier
Sep 14
ORD6:30 amChicago O'Hare Intl
13h 03m
1 stop
DSM7:33 pmDes Moines
Sep 21
DSM8:30 pmDes Moines
27h 53m
1 stop
ORD12:23 amChicago O'Hare Intl
$279

American Airlines flights from Illinois to Des Moines

Our best American Airlines deals on Illinois to Des Moines flight tickets
American Airlines
Sep 3
ORD10:45 pmChicago O'Hare Intl
1h 35m
DSM12:20 amDes Moines
Sep 7
DSM7:49 pmDes Moines
1h 48m
ORD9:37 pmChicago O'Hare Intl
$216
American Airlines
Sep 26
ORD6:59 amChicago O'Hare Intl
1h 40m
DSM8:39 amDes Moines
Oct 3
DSM2:44 pmDes Moines
1h 46m
ORD4:30 pmChicago O'Hare Intl
$217
American Airlines
Sep 5
ORD11:54 amChicago O'Hare Intl
1h 31m
DSM1:25 pmDes Moines
Sep 6
DSM6:10 amDes Moines
1h 50m
ORD8:00 amChicago O'Hare Intl
$226

momondo Fare Finder

 
Customize your flight search to find flights from Illinois to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Illinois to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoDes Moines

MDW Chicago Midway - DSM Des Moines

MDWDSM

Chicago Midway

Sat 9/5

6:00 pm-7:30 pm

Nonstop1h 30m

Des Moines

Mon 9/7

5:40 am-7:00 am

Nonstop1h 20m

$206

ChicagoDes Moines

MDW Chicago Midway - DSM Des Moines

MDWDSM

Chicago Midway

Fri 9/11

8:50 pm-10:15 pm

Nonstop1h 25m

Des Moines

Mon 9/14

5:40 am-7:00 am

Nonstop1h 20m

$206
Quickest round-trip

ChicagoDes Moines

MDW Chicago Midway - DSM Des Moines

MDWDSM

Chicago Midway

Fri 9/11

10:05 am-11:25 am

Nonstop1h 20m

Des Moines

Mon 9/14

5:40 am-7:00 am

Nonstop1h 20m

$206

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Thu 9/24

9:00 am-10:30 am

Nonstop1h 30m

Des Moines

Sat 9/26

1:26 pm-3:00 pm

Nonstop1h 34m

$215

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Tue 9/8

4:00 pm-5:28 pm

Nonstop1h 28m

Des Moines

Thu 9/10

11:32 am-1:15 pm

Nonstop1h 43m

$215

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Mon 9/28

6:59 am-8:39 am

Nonstop1h 40m

Des Moines

Wed 9/30

2:29 pm-4:15 pm

Nonstop1h 46m

$215

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Mon 9/7

10:45 pm-12:20 am

Nonstop1h 35m

Des Moines

Thu 9/10

5:56 pm-7:59 pm

Nonstop2h 03m

$215

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Mon 9/21

8:00 pm-9:28 pm

Nonstop1h 28m

Des Moines

Wed 9/23

11:32 am-1:15 pm

Nonstop1h 43m

$215

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Thu 9/17

7:25 am-7:57 pm

1 stop12h 32m

Des Moines

Sun 9/20

1:58 pm-1:30 pm

1 stop23h 32m

$219

ChicagoDes Moines

ORD Chicago O'Hare Intl - DSM Des Moines

ORDDSM

Chicago O'Hare Intl

Thu 9/10

7:25 am-7:57 pm

1 stop12h 32m

Des Moines

Thu 9/17

11:29 am-12:23 am

1 stop12h 54m

$228

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Illinois to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in October, then September is your next best option. Flight prices from Illinois to Des Moines during September average around $273.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Illinois to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $279. Flights from Illinois to Des Moines on a Tuesday will generally be more expensive and average around $470. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Illinois to Des Moines at noon for as low as $224. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $461. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Illinois to Des Moines flight route?

Fly from Chicago Midway to Des Moines for the best Illinois - Des Moines flight prices

What cabin class options are available on Illinois to Des Moines flights?

There are 4 cabin classes available to choose from on Illinois to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Illinois to Des Moines flights?

You could potentially save up to 22% on your flight if you consider stops on a Illinois to Des Moines flight.

Cheap Illinois to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Illinois to Des Moines

Best Price Found

$135

Fastest flight time

1h 11m

Direct flights

Every day

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Illinois in the past 72 hours is $135. The best round-trip flight deal from Illinois to Des Moines found on momondo in the last 72 hours is $273.
The fastest flight from Illinois to Des Moines takes 1h 11m
Direct flights go from Illinois to Des Moines every day.
There is 1 airport in Des Moines. From Illinois there are direct flights to Des Moines (DSM).
Search flight deals

Frequently asked questions about flying from Illinois to Des Moines

  • When did momondo last update prices for flights from Illinois to Des Moines Airport?

    Prices for flights from Illinois to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Illinois to Des Moines Airport?

  • How old do you have to be to fly from Illinois to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Illinois to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Illinois to Des Moines?

Best airlines flying from Illinois to Des Moines

Compare and see reviews for airlines that fly from Illinois to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $189Free CancellationRating
7.1
11,913 reviews
Search American Airlines flights
United AirlinesPriceFrom $189Free CancellationRating
7.4
10,111 reviews
Search United Airlines flights
SouthwestPriceFrom $209Free CancellationRating
8.0
4,218 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Urbandale
Newton
Osceola
Johnston
Boone
Oskaloosa
Norwalk
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Illinois to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Illinois to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Illinois to Des Moines with flexible booking policies on momondo?

Flights from Illinois to Des Moines with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Illinois to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Illinois. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Illinois to Des Moines right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Des Moines from Illinois. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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