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Cheap flights from Harrisburg to Key West from $265

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Harrisburg to Key West departing on 9/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Harrisburg to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
5:54 pm - 3:02 pmMDT  Harrisburg-EYW Key West
21h 08m1 stop Tampa St. Petersburg
Allegiant Air Logo
6:21 pm - 10:54 amEYW  Key West-MDT Harrisburg
16h 33m1 stop Orlando Sanford Intl
$322Allegiant Air
Fri, Aug 21 - Sun, Aug 30
Delta Logo
3:00 pm - 8:00 pmMDT  Harrisburg-EYW Key West
5h 00m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:19 pm - 11:40 pmEYW  Key West-MDT Harrisburg
5h 21m1 stop Atlanta Hartsfield-Jackson
$323Delta
Wed, Sep 16 - Tue, Sep 22
American Airlines Logo
6:15 am - 1:45 pmMDT  Harrisburg-EYW Key West
7h 30m1 stop Philadelphia
American Airlines Logo
6:27 pm - 11:25 pmEYW  Key West-MDT Harrisburg
4h 58m1 stop Charlotte Douglas
$323American Airlines
Wed, Sep 2 - Wed, Sep 9
Delta Logo
6:00 am - 10:48 amMDT  Harrisburg-EYW Key West
4h 48m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:02 pm - 11:50 pmEYW  Key West-MDT Harrisburg
5h 48m1 stop Atlanta Hartsfield-Jackson
$323Delta
Sat, Dec 12 - Tue, Dec 15
Multiple Airlines Logo
5:54 pm - 12:34 pmMDT  Harrisburg-EYW Key West
18h 40m1 stop Tampa St. Petersburg
Multiple Airlines Logo
6:21 pm - 10:54 amEYW  Key West-MDT Harrisburg
16h 33m1 stop Orlando Sanford Intl
$332Multiple Airlines
Mon, Aug 24 - Sun, Aug 30
Multiple Airlines Logo
5:54 pm - 12:34 pmMDT  Harrisburg-EYW Key West
18h 40m1 stop Tampa St. Petersburg
Multiple Airlines Logo
6:21 pm - 10:54 amEYW  Key West-MDT Harrisburg
16h 33m1 stop Orlando Sanford Intl
$335Multiple Airlines
Mon, Aug 24 - Sun, Aug 30
Multiple Airlines Logo
5:54 pm - 3:02 pmMDT  Harrisburg-EYW Key West
21h 08m1 stop Tampa St. Petersburg
Multiple Airlines Logo
7:53 pm - 5:26 pmEYW  Key West-MDT Harrisburg
21h 33m1 stop Tampa
$335Multiple Airlines
Fri, Aug 21 - Sun, Aug 30
Delta Logo
12:27 pm - 8:01 pmMDT  Harrisburg-EYW Key West
7h 34m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:02 pm - 11:50 pmEYW  Key West-MDT Harrisburg
5h 48m1 stop Atlanta Hartsfield-Jackson
$351Delta
Sat, Nov 7 - Wed, Nov 11
American Airlines Logo
5:45 am - 2:04 pmMDT  Harrisburg-EYW Key West
8h 19m1 stop Philadelphia
American Airlines Logo
1:47 pm - 11:25 pmEYW  Key West-MDT Harrisburg
9h 38m2 stops Miami Charlotte Douglas
$402American Airlines
Wed, Sep 16 - Tue, Sep 22
American Airlines Logo
3:46 pm - 11:07 pmMDT  Harrisburg-EYW Key West
7h 21m2 stops Charlotte Douglas Miami
American Airlines Logo
4:53 pm - 10:09 pmEYW  Key West-MDT Harrisburg
5h 16m1 stop Charlotte Douglas
$402American Airlines
Sat, Dec 12 - Tue, Dec 15

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American Airlines flights from Harrisburg to Key West

Our best American Airlines deals on Harrisburg to Key West flight tickets
American Airlines
Sep 2
MDT6:15 amHarrisburg
7h 30m
1 stop
EYW1:45 pmKey West
Sep 9
EYW6:27 pmKey West
4h 58m
1 stop
MDT11:25 pmHarrisburg
$323
American Airlines
Sep 2
MDT11:00 amHarrisburg
8h 39m
2 stops
EYW7:39 pmKey West
Sep 9
EYW6:27 pmKey West
4h 58m
1 stop
MDT11:25 pmHarrisburg
$402
American Airlines
Dec 4
MDT3:46 pmHarrisburg
5h 59m
1 stop
EYW9:45 pmKey West
Dec 8
EYW4:53 pmKey West
7h 25m
1 stop
MDT12:18 amHarrisburg
$410

Delta flights from Harrisburg to Key West

Our best Delta deals on Harrisburg to Key West flight tickets
Delta
Nov 7
MDT12:27 pmHarrisburg
7h 34m
1 stop
EYW8:01 pmKey West
Nov 11
EYW6:02 pmKey West
5h 48m
1 stop
MDT11:50 pmHarrisburg
$351
Delta
Nov 7
MDT12:27 pmHarrisburg
7h 34m
1 stop
EYW8:01 pmKey West
Nov 11
EYW6:02 pmKey West
5h 48m
1 stop
MDT11:50 pmHarrisburg
$370
Delta
Jan 26
MDT6:00 amHarrisburg
4h 58m
1 stop
EYW10:58 amKey West
Feb 24
EYW6:00 pmKey West
5h 38m
1 stop
MDT11:38 pmHarrisburg
$379

momondo Fare Finder

 
Customize your flight search to find flights from Harrisburg to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Harrisburg to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgKey West

MDT Harrisburg - EYW Key West

MDTEYW

Harrisburg

Fri 8/21

5:54 pm-3:02 pm

1 stop21h 08m

Key West

Sun 8/30

6:21 pm-10:54 am

1 stop16h 33m

$322
Quickest round-trip

HarrisburgKey West

MDT Harrisburg - EYW Key West

MDTEYW

Harrisburg

Wed 9/16

3:00 pm-8:00 pm

1 stop5h 00m

Key West

Tue 9/22

6:19 pm-11:40 pm

1 stop5h 21m

$323

HarrisburgKey West

MDT Harrisburg - EYW Key West

MDTEYW

Harrisburg

Wed 9/2

6:15 am-1:45 pm

1 stop7h 30m

Key West

Wed 9/9

6:27 pm-11:25 pm

1 stop4h 58m

$323

HarrisburgKey West

MDT Harrisburg - EYW Key West

MDTEYW

Harrisburg

Sat 12/12

6:00 am-10:48 am

1 stop4h 48m

Key West

Tue 12/15

6:02 pm-11:50 pm

1 stop5h 48m

$323

HarrisburgKey West

MDT Harrisburg - EYW Key West

MDTEYW

Harrisburg

Mon 8/24

5:54 pm-12:34 pm

1 stop18h 40m

Key West

Sun 8/30

6:21 pm-10:54 am

1 stop16h 33m

$332

HarrisburgKey West

MDT Harrisburg - EYW Key West

MDTEYW

Harrisburg

Mon 8/24

5:54 pm-12:34 pm

1 stop18h 40m

Key West

Sun 8/30

6:21 pm-10:54 am

1 stop16h 33m

$335

HarrisburgKey West

MDT Harrisburg - EYW Key West

MDTEYW

Harrisburg

Fri 8/21

5:54 pm-3:02 pm

1 stop21h 08m

Key West

Sun 8/30

7:53 pm-5:26 pm

1 stop21h 33m

$335

HarrisburgKey West

MDT Harrisburg - EYW Key West

MDTEYW

Harrisburg

Sat 11/7

12:27 pm-8:01 pm

1 stop7h 34m

Key West

Wed 11/11

6:02 pm-11:50 pm

1 stop5h 48m

$351

HarrisburgKey West

MDT Harrisburg - EYW Key West

MDTEYW

Harrisburg

Wed 9/16

5:45 am-2:04 pm

1 stop8h 19m

Key West

Tue 9/22

1:47 pm-11:25 pm

2 stops9h 38m

$402

HarrisburgKey West

MDT Harrisburg - EYW Key West

MDTEYW

Harrisburg

Sat 12/12

3:46 pm-11:07 pm

2 stops7h 21m

Key West

Tue 12/15

4:53 pm-10:09 pm

1 stop5h 16m

$402

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Harrisburg to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, October is the cheapest month to fly from Harrisburg to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $278. If you are unable to visit Key West during the month of October, then departing from Harrisburg during the month September is also very affordable. Most momondo users find prices during this month for around $345.

When to book flights from Harrisburg to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Harrisburg to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Harrisburg to Key West (MDT to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to Key West

Fastest flight time

4h 48m

Direct flights

None
The fastest flight from Harrisburg to Key West takes 4h 48m
There are no direct flights from Harrisburg to Key West. There are no popular flight routes from Harrisburg to Key West.
Search flight deals

Frequently asked questions about flying from Harrisburg to Key West

  • How far is Harrisburg to Key West by plane?

    Key West is 1122.0 mi away from Harrisburg. By plane, this route typically takes 4h 48m.

  • When did momondo last update prices for flights from Harrisburg Airport to Key West Airport?

    Prices for flights from Harrisburg Airport to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Harrisburg Airport to Key West Airport?

  • How old do you have to be to fly from Harrisburg Airport to Key West Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents required for your trip to Key West Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Key West Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Harrisburg to Key West?

Best airlines flying from Harrisburg to Key West

Compare and see reviews for airlines that fly from Harrisburg to Key West with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,864 reviews
Search American Airlines flights
DeltaPriceFrom $312Free CancellationRating
7.8
8,491 reviews
Search Delta flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to Key West?

Finding the right flight to Key West from Harrisburg is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Key West quick and easy, saving you time and money.

Can I find flights from Harrisburg to Key West with flexible booking policies on momondo?

Flights from Harrisburg to Key West with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Harrisburg to Key West?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Harrisburg to Key West.

I’m not ready to book a flight from Harrisburg to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Harrisburg are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Key West trip

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